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dermatophytes

" in MedChemExpress (MCE) Product Catalog:

23

Inhibitors & Agonists

1

Fluorescent Dye

1

Biochemical Assay Reagents

4

Natural
Products

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16246

    Fungal Infection
    Haloprogin is a potent antifungal agent. Haloprogin has activity against dermatophytes, Candida spp and a limited number of Gram-positive bacteria .
    Haloprogin
  • HY-108012

    Fungal Infection
    ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research .
    ME1111
  • HY-B0348

    Piritetrate; M-732

    Fungal Infection
    Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation .
    Liranaftate
  • HY-162296

    Fungal Infection
    Antibacterial agent 188 (compound 2d) is an antibacterial agent that inhibits dermatophyte activity .
    Antibacterial agent 188
  • HY-N3041

    Agoniadin; NSC 609065

    Fungal Infection Cancer
    Plumieride is an antifungal agent. Plumieride has strong fungitoxicity against some dermatophytes. Plumieride has little cytotoxic activity against the P388 leukaemia cell line with an IC50 of 85 μg/mL .
    Plumieride
  • HY-B0518A

    Fungal Antibiotic Infection
    Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
    Naftifine hydrochloride
  • HY-114518

    KP363

    Fungal Infection
    Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as  tinea pedis,  tinea cruris, tinea versicolor .
    Butenafine
  • HY-17583

    Fungal Apoptosis Antibiotic Endogenous Metabolite Infection Cancer
    Griseofulvin(Gris-PEG; Grifulvin) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal drug.
    Griseofulvin
  • HY-136767

    Fungal Antibiotic Infection
    Cladosporin is a fungal metabolite produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin completely inhibits growth of severa dermatophytes on agar medium at a concentration of 75 μg/mL .
    Cladosporin
  • HY-19584

    Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .
    Variotin
  • HY-17583S

    Isotope-Labeled Compounds Fungal Apoptosis Antibiotic Endogenous Metabolite Infection Cancer
    Griseofulvin-d3 is the deuterium labeled Griseofulvin. Griseofulvin (Gris-PEG) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal agent[1][2].
    Griseofulvin-d3
  • HY-10445

    Azoline; R126638

    Fungal Infection
    Pramiconazole is a broad-spectrum antifungal agent with oral activity. Pramiconazole has a good affinity for 14α-demethylase. Pramiconazole can be used in the study of fungal infections in the local skin, hair, nails, oral cavity, and genital mucosa .
    Pramiconazole
  • HY-B0319

    UK-20349

    Fungal Antibiotic Infection
    Tioconazole (UK-20349) is an antifungal imidazole derivative with broad spectrum activity. Tioconazole has inhibitory active aginst several dermatophytes and several yeasts with MIC50s <3.12 mg/L and <9 mg/L, respectively .
    Tioconazole
  • HY-B0518AS

    Fungal Antibiotic Infection
    Naftifine-d3 (hydrochloride) is the deuterium labeled Naftifine hydrochloride. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition[1].
    Naftifine-d3 hydrochloride
  • HY-N2472

    Castanogenin

    Bacterial Infection
    Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes . Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE .
    Medicagenic acid
  • HY-17643

    VT-1161

    Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .
    Oteseconazole
  • HY-B0450S

    HOE296b-d11

    Fungal Bacterial Ferroptosis Autophagy Infection Cancer
    Ciclopirox-d11 is the deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].
    Ciclopirox-d11
  • HY-B0450S1

    Isotope-Labeled Compounds Fungal Bacterial Ferroptosis Autophagy Infection Cancer
    Ciclopirox-d11 (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].
    Ciclopirox-d11 sodium
  • HY-15660
    Efinaconazole
    1 Publications Verification

    KP-103

    Fungal Infection
    Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively . Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species .
    Efinaconazole
  • HY-B0450
    Ciclopirox
    4 Publications Verification

    HOE296b

    Fungal Bacterial Ferroptosis Autophagy Infection Inflammation/Immunology Cancer
    Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox also has anticancer and anti-inflammatory effect .
    Ciclopirox
  • HY-B0450A
    Ciclopirox olamine
    4 Publications Verification

    Ciclopirox ethanolamine; HOE 296

    Fungal Bacterial Ferroptosis Infection Cancer
    Ciclopirox olamine (Ciclopirox ethanolamine) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox olamine also has anticancer and anti-inflammatory effect .
    Ciclopirox olamine
  • HY-15660S

    KP-103-d4

    Isotope-Labeled Compounds Fungal Infection
    Efinaconazole-d4 is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively[1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species[1].
    Efinaconazole-d4
  • HY-B0450AG

    Ciclopirox ethanolamine; HOE 296

    Bacterial Fungal Ferroptosis Infection
    Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .
    Ciclopirox olamine

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