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Results for "

endonuclease

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endonuclease (5) AP-1 (1) Apoptosis (2) Autophagy (2) CMV (2) DNA/RNA Synthesis (8) Endogenous Metabolite (1) FLAP (7) HIF/HIF Prolyl-Hydroxylase (1) Influenza Virus (33) IRE1 (1) Isotope-Labeled Compounds (2) MDM-2/p53 (1) NF-κB (1) Parasite (3) Reactive Oxygen Species (1) Topoisomerase (1) VEGFR (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (1) Infection (34) Inflammation/Immunology (2) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

MCE Kits

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Endonuclease

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-143776

Cap-dependent endonuclease-IN-22

Influenza Virus Infection

Cap-dependent endonuclease-IN-22 is a potent cap-dependent endonuclease (CEN) inhibitor .

*Cap-dependent endonuclease-IN-22*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-22 is a potent cap-dependent endonuclease (CEN) inhibitor .

HY-132894

*Cap-dependent endonuclease-IN-1*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-1 is an orally active cap-dependent endonuclease inhibitor with high potency. Cap-dependent endonuclease-IN-1 can be used for the research of influenza .

HY-143762

*Cap-dependent endonuclease-IN-12*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-12 (EXP-35) is a potent Cap-dependent endonuclease inhibitor with low cytotoxicity. Cap-dependent endonuclease-IN-12 shows inhibitory activity against H1N1 .

HY-143770

*Cap-dependent endonuclease-IN-16*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-16 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-16 is a pyridone polycyclic derivative. Cap-dependent endonuclease-IN-16 has the potential for the research of influenza (extracted from patent CN112778330A, compound 15A) .

HY-143749

*Cap-dependent endonuclease-IN-6*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-6 (compound 13) is a cap-dependent endonuclease (CEN) inhibitor. Cap-dependent endonuclease-IN-6 shows inhibition against influenza virus (EC₅₀=38.21 nM) .

HY-143775

*Cap-dependent endonuclease-IN-20*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-20 is a *cap-dependent endonuclease* (CEN)** inhibitor. Cap-dependent endonuclease-IN-20 shows antiviral activity against influenza virus A/Hanfang/359/95 (H3N2) with IC₅₀ of 4.82 μM (CN112940009A; DSC801) .

HY-143771

*Cap-dependent endonuclease-IN-17*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-17 is a *cap-dependent endonuclease* (CEN)** inhibitor. Cap-dependent endonuclease-IN-17 shows antiviral activity against influenza virus A/Hanfang/359/95 (H3N2) with IC₅₀ of 1.29 μM (CN112898346A; DSC701) .

HY-143768

*Cap-dependent endonuclease-IN-14*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-14 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-14 inhibits the replication of influenza virus. Cap-dependent endonuclease-IN-14 has the potential for the research of viral infections caused by influenza viruses (extracted from patent CN113620948A, compound 1-c) .

HY-143769

*Cap-dependent endonuclease-IN-15*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-15 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-15 inhibits the replication of influenza virus. Cap-dependent endonuclease-IN-15 has the potential for the research of viral infections caused by influenza viruses (extracted from patent CN113226327A, compound c-1) .

HY-144066

*Cap-dependent endonuclease-IN-21*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-21 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-21 inhibits the replication of influenza virus. ap-dependent endonuclease-IN-21 has the potential for the research of influenza virus infection (influenza A) (extracted from patent WO2021233302A1, compound 8B or 8A) .

HY-144067

*Cap-dependent endonuclease-IN-23*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-23 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-23 inhibits the replication of influenza virus. ap-dependent endonuclease-IN-23 has the potential for the research of influenza virus infection (influenza A) (extracted from patent WO2021233302A1, compound 8A or 8B) .

HY-143781

*Cap-dependent endonuclease-IN-26*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-26 is a *cap-dependent endonuclease* (CEN) inhibitor with an IC₅₀** of 286 nM. Cap-dependent endonuclease-IN-26 shows antiviral activity against many influenza A and B strains .

HY-144065

*Cap-dependent endonuclease-IN-19*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-19 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-19 is a spirocyclic pyridone derivative. Cap-dependent endonuclease-IN-19 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent CN111410661A, compound 1) .

HY-143766

*Cap-dependent endonuclease-IN-13*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-13 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-13 has the potential for the research of influenza virus infection (only influenza A) (extracted from patent WO2021180147A1, compound I-1) .

HY-146271

*pUL89 Endonuclease-IN-2*	CMV	Infection
pUL89 Endonuclease-IN-2 (Compound 15k) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC₅₀ of 3.0 μM. Antiviral activities .

HY-146270

*pUL89 Endonuclease-IN-1*	CMV	Infection
pUL89 Endonuclease-IN-1 (Compound 13d) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC₅₀ value of 0.88 μM and has antiviral activitiy .

HY-144068

*Cap-dependent endonuclease-IN-25*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-25 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-25 is a macrocyclic pyridotriazine derivative. Cap-dependent endonuclease-IN-25 has the potential for the research of viral infections caused by viruses belonging to the Orthomyxoviridae family (extracted from patent WO2020075080A1, compound 4) .

HY-143747

*Cap-dependent endonuclease-IN-5*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-5 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-5 inhibits influenza virus well, and/or has lower cytotoxicity, better in vivo pharmacokinetic properties and in vivo pharmacodynamic properties (extracted from patent WO2020078401A1, compound 13-1) .

HY-143752

*Cap-dependent endonuclease-IN-8*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-8 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-8 inhibits replication of orthomyxoviruses (including influenza A, influenza B and influenza C) (extracted from patent CN111410661A, compound I-196) .

HY-143744

*Cap-dependent endonuclease-IN-3*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-3 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-3 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-3 has the potential for the research of influenza A and influenza B infection (extracted from patent WO2019141179A1, compound VI-1) .

HY-143743

*Cap-dependent endonuclease-IN-2*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-2 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-2 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent WO2019052565A1, compound 28) .

HY-143755

*Cap-dependent endonuclease-IN-9*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-9 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-9 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-9 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent CN112521386A, compound VI-1) .

HY-143750

*Cap-dependent endonuclease-IN-7*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-7 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-7 Inhibits the synthesis of viral mRNA and eventually inhibits virus proliferation. Cap-dependent endonuclease-IN-7 has the potential for the research of viral infections (including influenza A, influenza B and influenza C) (extracted from patent WO2020177715A1, compound 5)

HY-143757

*Cap-dependent endonuclease-IN-10*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-10 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-10 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo pharmacokinetic and in vivo pharmacodynamic properties, and better hepatic microsomal stability. Cap-dependent endonuclease-IN-10 has the potential for the research of viral infections (including influenza A, influenza B and influenza C) (extracted from patent WO2021129799A1, compound 1-1) .

HY-163147

*PAN endonuclease-IN-1*	Influenza Virus	Infection
PAN endonuclease-IN-1 (Compound 23) is a potent PAN endonuclease inhibitor, with K_d values of 277 μM, 384 μM and 328 μM for WT, I38T and E23K PA_N endonucleases, respectively. The RNA-dependent RNA polymerase acidic N-terminal (PAN) endonuclease, a critical component of influenza viral replication machinery, is an antiviral target .

HY-162242

*Cap-dependent endonuclease-IN-27*	Influenza Virus	Infection
Cap-dependent endonuclease-IN-27 (Compound 8) is an orally active potent cap-dependent endonuclease (CEN) inhibitor. Cap-dependent endonuclease-IN-27, an antiviral agent, shows activity against influenza B virus. Cap-dependent endonuclease-IN-27 has inhibitory activity against IFV A/WSN/33 (H1N1) polymerase (EC₅₀ = 12.26 nM) .

HY-136485

FEN1-IN-4

FLAP Cancer

FEN1-IN-4 (Compound 2) is a human flap endonuclease-1 (hFEN1) inhibitor .

FEN1-IN-4	FLAP	Cancer
FEN1-IN-4 (Compound 2) is a human flap endonuclease-1 (hFEN1) inhibitor .

HY-122695

FEN1-IN-2 1 Publications Verification	FLAP	Cancer
FEN1-IN-2 (compound 20) is a *flap endonuclease* 1 (FEN1) inhibitor, with IC50** values of 3 nM and 226 nM for FEN1 and XPG, respectively .

HY-136484

FEN1-IN-3

FLAP Cancer

FEN1-IN-3 (Compound 4) is a human flap endonuclease-1 (hFEN1) inhibitor. FEN1-IN-3 stabilizes hFEN1 with an EC₅₀ of 6.8 μM .

FEN1-IN-3	FLAP	Cancer
FEN1-IN-3 (Compound 4) is a human flap endonuclease-1 (hFEN1) inhibitor. FEN1-IN-3 stabilizes hFEN1 with an EC₅₀ of 6.8 μM .

HY-N10581

Flutimide	Influenza Virus	Infection
Flutimide is a novel *endonuclease* inhibitor of influenza virus. Flutimide selectively inhibits endonuclease with an IC₅₀ value of 3 μM. Flutimide shows antiviral activity in cell culture. Flutimide can be used for the research of acute contagious respiratory disease, such as influenza .

HY-W014622

CRT0044876	DNA/RNA Synthesis	Cancer
CRT0044876 is a potent and selective *apurinic/apyrimidinic endonuclease* 1 (APE1) inhibitor (IC₅₀*=~3 μM). CRT0044876 inhibits the AP endonuclease*, 3′-phosphodiesterase and 3′-phosphatase activities of APE1, and is a specific inhibitor of the exonuclease III family of enzymes to which APE1 belongs. CRT0044876 potentiates the cytotoxicity of several DNA base-targeting compounds .

HY-P2963

Nuclease P1	Endogenous Metabolite	Others
Nuclease P1 is a single-stranded specific endonuclease, it hydrolyzes nucleic acids into 5'-mononucleotides and cleaves the single-stranded region of a double-stranded nucleic acid. Nuclease P1 is one of the most well-known single stranded specific nucleases in the field of molecular biology, it is widely used in the pharmaceutical and food industries .

HY-152078

Influenza virus-IN-6	Influenza Virus	Infection
Influenza virus-IN-6 (Compound 35) is a potent influenza N-terminal domain of the polymerase acidic protein subunit (PA_N) endonuclease inhibitor with an IC₅₀ of 0.20 μM .

HY-116770

PFM01	Endonuclease	Cancer
PFM01, N-alkylated Mirin derivative, is a MRE11 endonuclease inhibitor. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR) .

HY-143492

Influenza virus-IN-1	Influenza Virus	Inflammation/Immunology
Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC₅₀ of 2.46 µM and CC₅₀ of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PA_N endonuclease with EC₅₀ of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities .

HY-143493

Influenza virus-IN-2	Influenza Virus	Inflammation/Immunology
Influenza virus-IN-2 (compound 19) is a potent influenza virus inhibitor with an EC₅₀ of 2.58 µM and CC₅₀ of 150.85 µM. Influenza virus-IN-2 shows a concentration dependent inhibition activity for PA_N endonuclease with EC₅₀ of 489.39 nM. Influenza virus-IN-2 shows shows anti-influenza A virus activities .

HY-B2098

Lucanthone

Autophagy Parasite Cancer

Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1).
HY-B2098A

Lucanthone hydrochloride

Autophagy Parasite Cancer

Lucanthone hydrochloride is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1).

Lucanthone	Autophagy Parasite	Cancer
Lucanthone is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1).

Lucanthone hydrochloride	Autophagy Parasite	Cancer
Lucanthone hydrochloride is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1).

HY-109025A

Baloxavir 15+ Cited Publications Baloxavir acid; S-033447	Influenza Virus	Infection
Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective *cap-dependent endonuclease* (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses**. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity .

HY-153790

FEN1-IN-5

FLAP Cancer

FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC₅₀=12 nM), involving in DNA repair .

FEN1-IN-5	FLAP	Cancer
FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap *endonuclease-1* (FEN1, IC₅₀=12 nM), involving in DNA repair .

HY-153791

FEN1-IN-6	FLAP	Cancer
FEN1-IN-6 (compound 9) is a potent inhibitor of Flap *endonuclease-1* (FEN1, IC₅₀=10 nM), involving in mammalian cells to repair DNA damage. FEN1-IN-6 also targets to related endonuclease, xeroderma pigmentosum G (XPG) with an IC₅₀ value of 23 nM .

HY-W751835

Baloxavir-d4 15+ Cited Publications Baloxavir acid-d₄; S-033447-d₄	Isotope-Labeled Compounds	Others
Baloxavir-d₄ (Baloxavir acid-d₄; S-033447-d₄) is the deuterium-labeled Baloxavir (HY-109025A). Baloxavir-d₄ (Baloxavir-d₄ acid), derived from the proagent Baloxavir-d₄ marboxil, is a first-in-class, potent and selective *cap-dependent endonuclease* (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses**. Baloxavir-d₄ inhibits viral RNA transcription and replication and has potently antiviral activity .

HY-153792

FEN1-IN-7	FLAP	Cancer
FEN1-IN-7 (compound 16) is a selective inhibitor of Flap *endonuclease-1* (FEN1, IC₅₀=18 nM), involving in mammalian cells to repair DNA damage. FEN1-IN-7 also targets to related endonuclease, xeroderma pigmentosum G (XPG) with an IC₅₀ value of 3.04 μM. FEN1-IN-7 increases the cellular sensitivity of cancer cells to potent DNA alkylating agents or methylating agents .

HY-112684

RO-7

Influenza Virus Infection

RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses.

RO-7	Influenza Virus	Infection
RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses.

HY-B1099

Hycanthone 2 Publications Verification	DNA/RNA Synthesis Topoisomerase Parasite	Infection
Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits *apurinic endonuclease-1 (APE1)* by direct protein binding with a K_D of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent .

HY-19357

E3330 2 Publications Verification APX-3330	DNA/RNA Synthesis NF-κB AP-1 HIF/HIF Prolyl-Hydroxylase VEGFR Reactive Oxygen Species	Cardiovascular Disease Neurological Disease Cancer
E3330 (APX-3330) is a direct, orally active and selective inhibitor of *Ape-1 (apurinic/apyrimidinic endonuclease* 1)/Ref-1 (redox factor-1) redox. E3330 is able to impair tumor growth and blocks the activity of NF-κB, AP-1, and HIF-1α** in pancreatic cancer. E3330 shows anticancer activities .

HY-145758

FEN1-IN-SC13

1 Publications Verification

Endonuclease Cancer

FEN1-IN-SC13 is a potent DNA fragmentation endonuclease 1 (FEN1) inhibitor (CN106692155A, SC13) .
HY-148078

PFM03

Endonuclease Others

PFM03 is a MRE11 Endonuclease inhibitor. PFM03 regulates DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) .

HY-153570

Influenza virus-IN-7	Influenza Virus	Infection
Influenza virus-IN-7 (Example 16) is an orally active cap-dependent endonuclease inhibitor that can be used for the research of influenza viral infectious diseases .

HY-109025

Baloxavir marboxil 5 Publications Verification S-033188; RG 6152	Influenza Virus	Infection
Baloxavir marboxil (S-033188) is a selective inhibitor of influenza cap-dependent *endonuclease. Baloxavir marboxil, a potent antiviral agent, shows activity against influenza A* and B virus .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N10581

Flutimide	Microorganisms	Influenza Virus
Flutimide is a novel *endonuclease* inhibitor of influenza virus. Flutimide selectively inhibits endonuclease with an IC₅₀ value of 3 μM. Flutimide shows antiviral activity in cell culture. Flutimide can be used for the research of acute contagious respiratory disease, such as influenza .

Species:	Human (3)
Tag:	His (5) Tag Free (2) Myc (1)
Source:	Sf9 insect cells (1) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source

HY-P74734

	NEIL1 Protein, Human (His) endonuclease 8-like 1; endonuclease VIII-like 1; FPG1; NEH1; NEIL1	Human	E. coli
	NEIL1 is a critical base excision repair enzyme that recognizes and eliminates damaged bases and preferentially selects oxidized pyrimidines such as thymine glycol, Fapy, and 5-hydroxyuracil. Although NEIL1 has limited activity toward 8-oxoguanine, it has excellent AP lyase activity and introduces nicking by eliminating β-δ. NEIL1 Protein, Human (His) is the recombinant human-derived NEIL1 protein, expressed by E. coli , with C-His labeled tag. The total length of NEIL1 Protein, Human (His) is 390 a.a., with molecular weight of ~45 kDa.

HY-P70348

	*Flap endonuclease* 1/FEN-1 Protein, Human** rHuFlap endonuclease 1/FEN-1; Flap endonuclease 1; FEN-1; DNase IV; Flap Structure-Specific endonuclease 1; Maturation Factor 1; MF1; hFEN-1; FEN1; RAD2	Human	E. coli
	Flap endonuclease 1 (FEN-1) is a structure-specific nuclease crucial for DNA replication and repair. In replication, it cleaves 5'-overhanging flaps, guiding DNA polymerase and creating a nick for ligation. FEN-1 is integral to the long patch base excision repair pathway, preventing genomic instability. It exhibits 5'-3' exonuclease and RNase H activities, playing roles in rDNA and mitochondrial DNA replication and repair. Flap endonuclease 1/FEN-1 Protein, Human is the recombinant human-derived Flap endonuclease 1/FEN-1 protein, expressed by E. coli , with tag free. The total length of Flap endonuclease 1/FEN-1 Protein, Human is 380 a.a., with molecular weight of ~44.5 kDa.

HY-P700010

	*Flap endonuclease* 1/FEN-1 Protein, Human (His, Myc)** rHuFlap endonuclease 1/FEN-1; Flap endonuclease 1; FEN-1; DNase IV; Flap Structure-Specific endonuclease 1; Maturation Factor 1; MF1; hFEN-1; FEN1; RAD2	Human	E. coli
	Flap endonuclease 1 (FEN-1) is a structure-specific nuclease crucial for DNA replication and repair. In replication, it cleaves 5'-overhanging flaps, guiding DNA polymerase and creating a nick for ligation. FEN-1 is integral to the long patch base excision repair pathway, preventing genomic instability. It exhibits 5'-3' exonuclease and RNase H activities, playing roles in rDNA and mitochondrial DNA replication and repair. Flap endonuclease 1/FEN-1 Protein, Human (His, Myc) is the recombinant human-derived Flap endonuclease 1/FEN-1 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag. The total length of Flap endonuclease 1/FEN-1 Protein, Human (His, Myc) is 380 a.a., with molecular weight of ~50.0 kDa.

HY-P77727

	CRISPR-Cas9 Protein, S. pyogenes (His) CRISPR-associated endonuclease Cas9/Csn1; cas9; SpCas9; SpyCas9	Others	E. coli
	The CRISPR-Cas9 protein is part of an immune system that defends against genetic elements. It processes RNA and aids in cleaving DNA targets. Protein and guide RNAs are necessary for its function. The protein recognizes specific sequences to distinguish self from nonself and provides immunity against matching genetic elements. CRISPR-Cas9 Protein, S. pyogenes (His) is the recombinant CRISPR-Cas9 protein, expressed by E. coli , with His tagged. The total length of CRISPR-Cas9 Protein, S. pyogenes (His) is 1367 a.a., with molecular weight of ~163 kDa.

HY-P701235

	CRISPR-Cas9 Protein, S. pyogenes (NLS) CRISPR-associated endonuclease Cas9/Csn1; cas9; SpCas9; SpyCas9	Others	E. coli
	The CRISPR-Cas9 protein is part of an immune system that defends against genetic elements. It processes RNA and aids in cleaving DNA targets. Protein and guide RNAs are necessary for its function. The protein recognizes specific sequences to distinguish self from nonself and provides immunity against matching genetic elements. CRISPR-Cas9 Protein, S. pyogenes (NLS) is the recombinant CRISPR-Cas9 protein, expressed by E. coli , with tag free. The total length of CRISPR-Cas9 Protein, S. pyogenes (NLS) is 1368 a.a., with molecular weight of ~160 kDa.

HY-P77728

	GMP-CRISPR-Cas9 Protein, S. pyogenes (His) CRISPR-associated endonuclease Cas9/Csn1; cas9; SpCas9; SpyCas9	Others	E. coli
	The CRISPR-Cas9 protein is part of an immune system that defends against genetic elements. It processes RNA and aids in cleaving DNA targets. Protein and guide RNAs are necessary for its function. The protein recognizes specific sequences to distinguish self from nonself and provides immunity against matching genetic elements. GMP-CRISPR-Cas9 Protein, S. pyogenes (His) is the recombinant GMP-CRISPR-Cas9 protein, expressed by E. coli , with His labeled tag. The total length of GMP-CRISPR-Cas9 Protein, S. pyogenes (His) is 1367 a.a., with molecular weight of ~163 kDa.

HY-P75328

	CRISPR-Cas9 Protein, Streptococcus pyogenes M1 (sf9, His) Cas9; CRISPR; CRISPR-associated endonuclease Cas9/Csn1; SpyCas9	Others	Sf9 insect cells
	The CRISPR-Cas9 protein is part of an immune system that defends against genetic elements. It processes RNA and aids in cleaving DNA targets. Protein and guide RNAs are necessary for its function. The protein recognizes specific sequences to distinguish self from nonself and provides immunity against matching genetic elements. CRISPR-Cas9 Protein, Streptococcus pyogenes M1 (sf9, His) is the recombinant CRISPR-Cas9 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of CRISPR-Cas9 Protein, Streptococcus pyogenes M1 (sf9, His) is 1368 a.a., with molecular weight of ~163 kDa.

Cat. No.	Product Name	Chemical Structure

HY-W751835

Baloxavir-d4

15+ Cited Publications

Baloxavir-d₄ (Baloxavir acid-d₄; S-033447-d₄) is the deuterium-labeled Baloxavir (HY-109025A). Baloxavir-d₄ (Baloxavir-d₄ acid), derived from the proagent Baloxavir-d₄ marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir-d₄ inhibits viral RNA transcription and replication and has potently antiviral activity .

HY-109025AS

Baloxavir-d5
Baloxavir-d₅ is deuterium labeled Baloxavir. Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity[1][2].

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