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Results for "

fluorescent

" in MCE Product Catalog:

By Targets:	Adenosine Receptor (1) Adrenergic Receptor (2) Aldehyde Dehydrogenase (ALDH) (1) Amyloid-β (10) Angiotensin-converting Enzyme (ACE) (2) Antibiotic (3) Apoptosis (4) Arp2/3 Complex (1) Autophagy (3) Bacterial (13) Bcl-2 Family (1) Btk (1) c-Myc (1) Calcium Channel (1) Cannabinoid Receptor (2) Caspase (5) Cathepsin (1) Cholinesterase (ChE) (3) Complement System (1) Cytochrome P450 (2) DNA Stain (34) DNA/RNA Synthesis (6) Endogenous Metabolite (2) ERK (1) Estrogen Receptor/ERR (1) Ferroptosis (1) Fungal (2) G-quadruplex (2) GABA Receptor (1) Glucosidase (1) GPR55 (1) HDAC (2) HIF/HIF Prolyl-Hydroxylase (3) HIV (1) HSP (3) HSV (1) Huntingtin (1) IKK (1) Influenza Virus (2) Integrin (2) JAK (1) Keap1-Nrf2 (1) Leukotriene Receptor (1) mAChR (1) Macrophage migration inhibitory factor (MIF) (1) MAGL (1) Microtubule/Tubulin (3) Mitochondrial Metabolism (2) MMP (3) Monoamine Oxidase (1) Monoamine Transporter (2) Myosin (1) Na+/K+ ATPase (1) nAChR (1) Neuropeptide Y Receptor (1) NF-κB (1) p38 MAPK (1) Parasite (4) Phosphatase (2) Phospholipase (2) PKC (1) Potassium Channel (1) PROTAC Linkers (2) Proteasome (3) Raf (1) Reactive Oxygen Species (30) ROS Kinase (1) SARS-CoV (1) Ser/Thr Protease (1) Smo (1) Sodium Channel (1) Topoisomerase (2)
By Research Areas:	Cancer (100) Cardiovascular Disease (7) Infection (22) Inflammation/Immunology (28) Metabolic Disease (24) Neurological Disease (54)

By Targets:

Adenosine Receptor (1)

Adrenergic Receptor (2)

Aldehyde Dehydrogenase (ALDH) (1)

Amyloid-β (10)

Angiotensin-converting Enzyme (ACE) (2)

Antibiotic (3)

Apoptosis (4)

Arp2/3 Complex (1)

Autophagy (3)

Bacterial (13)

Bcl-2 Family (1)

Btk (1)

c-Myc (1)

Calcium Channel (1)

Cannabinoid Receptor (2)

Caspase (5)

Cathepsin (1)

Cholinesterase (ChE) (3)

Complement System (1)

Cytochrome P450 (2)

DNA Stain (34)

DNA/RNA Synthesis (6)

Endogenous Metabolite (2)

ERK (1)

Estrogen Receptor/ERR (1)

Ferroptosis (1)

Fungal (2)

G-quadruplex (2)

GABA Receptor (1)

Glucosidase (1)

GPR55 (1)

HDAC (2)

HIF/HIF Prolyl-Hydroxylase (3)

HIV (1)

HSP (3)

HSV (1)

Huntingtin (1)

IKK (1)

Influenza Virus (2)

Integrin (2)

JAK (1)

Keap1-Nrf2 (1)

Leukotriene Receptor (1)

mAChR (1)

Macrophage migration inhibitory factor (MIF) (1)

MAGL (1)

Microtubule/Tubulin (3)

Mitochondrial Metabolism (2)

MMP (3)

Monoamine Oxidase (1)

Monoamine Transporter (2)

Myosin (1)

Na+/K+ ATPase (1)

nAChR (1)

Neuropeptide Y Receptor (1)

NF-κB (1)

p38 MAPK (1)

Parasite (4)

Phosphatase (2)

Phospholipase (2)

PKC (1)

Potassium Channel (1)

PROTAC Linkers (2)

Proteasome (3)

Raf (1)

Reactive Oxygen Species (30)

ROS Kinase (1)

SARS-CoV (1)

Ser/Thr Protease (1)

Smo (1)

Sodium Channel (1)

Topoisomerase (2)

By Research Areas:

Cancer (100)

Cardiovascular Disease (7)

Infection (22)

Inflammation/Immunology (28)

Metabolic Disease (24)

Neurological Disease (54)

282

Inhibitors & Agonists

770

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas

HY-D1499

Fluorescent red 610
Others Others

Fluorescent red 610 is a fluorescent dye with an excitation peak at 590 nm and an emission peak at 610 nm.
HY-D1495

Fluorescent red NIR 880
DY 880
Others Others

Fluorescent red NIR 880 is a fluorescent dye.

Fluorescent red 610	Others	Others
Fluorescent red 610 is a fluorescent dye with an excitation peak at 590 nm and an emission peak at 610 nm.

Fluorescent red NIR 880 DY 880	Others	Others
Fluorescent red NIR 880 is a fluorescent dye.

HY-136247

Cyanine 5 Tyramide Tyramide-Cy5	DNA Stain Others	Others
Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.

HY-136248

Cyanine 3 Tyramide Tyramide-Cy3	DNA Stain Others	Others
Cyanine 3 Tyramide (Tyramide-Cy3), an orange fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.

HY-P3474

Mca-PLGL-Dpa-AR-NH2
MMP Cancer

Mca-PLGL-Dpa-AR-NH2 is a fluorescent peptide MMP substrate.

Mca-PLGL-Dpa-AR-NH2	MMP	Cancer
Mca-PLGL-Dpa-AR-NH2 is a fluorescent peptide MMP substrate.

HY-147889

BBR-BODIPY	Apoptosis Caspase Bcl-2 Family	Others
BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins.

HY-D1567

Cy7.5 NHS ester	Others	Others
Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study.

HY-D1151

HKOH-1
Reactive Oxygen Species Others

HKOH-1 is a highly sensitive and selective fluorescent probe for detecting endogenous hydroxyl radicals.

HKOH-1	Reactive Oxygen Species	Others
HKOH-1 is a highly sensitive and selective fluorescent probe for detecting endogenous hydroxyl radicals.

HY-D0208

Fluorescein sodium Uranine sodium	Others	Cancer
Fluorescein (Uranine) sodium is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) sodium is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes.

HY-D1681

Rhod-590 AM Ester
Others Others

Rhod-590 AM Ester is a fluorescent dye. Rhod-590 AM Ester can be used as a fluorescent indicator for calcium determination.

Rhod-590 AM Ester	Others	Others
Rhod-590 AM Ester is a fluorescent dye. Rhod-590 AM Ester can be used as a fluorescent indicator for calcium determination.

HY-137834

Gly-Pro-AMC hydrobromide	Others	Others
Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity.

HY-D1610

BODIPY FL C5	Others	Others
BODIPY FL C₅ is a *green fluorescent* fatty acid*. BODIPY FL C₅ can be used as a precursor for the synthesis of various fluorescent* phospholipids. BODIPY FL C₅ is relatively insensitive to the environment and fluoresces in both water-soluble and lipid environments.

HY-D1485

3,3'-Diethylthiacyanine iodide	Bacterial	Others
3,3'-Diethylthiacyanine iodide is a cyanine fluorescent dye. 3,3'-Diethylthiacyanine iodide manifestes a pronounced affinity for bacterial cells.

HY-D1685

BZiPAR
Others Others

BZiPAR is a fluorescent probe. BZiPAR also is a substrate of trypsin that becomes fluorescent after cleavage by the protease.
HY-147177

Bodipy 8-chloromethane
Others Others

BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe.
HY-W040143

2',7'-Dichlorofluorescein
Reactive Oxygen Species Cancer

2',7'-Dichlorofluorescein acts as a fluorescent probe (Ex=496 nm and Em=525 nm) for reactive oxygen species (ROS) measurement.
HY-134321

8-Azido-cAMP
Others Others

8-Azido-cAMP is a fluorescent cAMP analog, acting as the model target of detecting cAMP.

BZiPAR	Others	Others
BZiPAR is a fluorescent probe. BZiPAR also is a substrate of trypsin that becomes fluorescent after cleavage by the protease.

Bodipy 8-chloromethane	Others	Others
BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe.

2',7'-Dichlorofluorescein	Reactive Oxygen Species	Cancer
2',7'-Dichlorofluorescein acts as a fluorescent probe (Ex=496 nm and Em=525 nm) for reactive oxygen species (ROS) measurement.

8-Azido-cAMP	Others	Others
8-Azido-cAMP is a fluorescent cAMP analog, acting as the model target of detecting cAMP.

HY-D1608

BODIPY FL Thapsigargin	Calcium Channel Others	Others
BODIPY FL Thapsigargin is a potent green fluorescent dye. BODIPY FL Thapsigargin inhibits intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum. BODIPY FL Thapsigargin used for investigation of thapsigargin binding sites in live cells.

HY-131016

IHR-Cy3
Smo Cancer

IHR-Cy3 is a potent fluorescent Smo antagonist with an IC₅₀ of 100 nM.
HY-104056

Fura Red
Others Others

Fura Red is a Ca²⁺-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca²⁺].

IHR-Cy3	Smo	Cancer
IHR-Cy3 is a potent fluorescent Smo antagonist with an IC₅₀ of 100 nM.

Fura Red	Others	Others
Fura Red is a Ca²⁺-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca²⁺].

HY-D1055

MitoSOX Red	Reactive Oxygen Species Mitochondrial Metabolism	Cancer
MitoSOX red, a fluorescent dye, specifically targets mitochondrial ROS. MitoSOX red can be used to observed the distribution of mitochondrial ROS.

HY-D1090

JOE	DNA Stain Others	Others
JOE is a fluorescent dye and can be used as a fluorescent label in DNA sequencing, PCR, and LCR amplifications. JOE possesses an absorbance of 525 nm and an emission of 550 nm.

HY-130015

HKSOX-1 (5/6-mixture)	Reactive Oxygen Species	Others
HKSOX-1 is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 exhibits excellent selectivity and sensitivity towards superoxide anion radical.

HY-129887

Fluorescein diphosphate tetraammonium	Others	Others
Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product.

HY-145800

GFP150 TFA
Others Others

GFP150 TFA is a green fluorescent protein used for labeling proteins.
HY-D1668

Biotin-11-dCTP
Others Others

Biotin-11-dCTP is a fluorescent dye for DNA labeling.

GFP150 TFA	Others	Others
GFP150 TFA is a green fluorescent protein used for labeling proteins.

Biotin-11-dCTP	Others	Others
Biotin-11-dCTP is a fluorescent dye for DNA labeling.

HY-103373

PE154	Cholinesterase (ChE)	Neurological Disease
PE154 (Compound 13) is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC₅₀s=280 pM and 16 nM, respectively). PE154 can label β-amyloid plaques in histochemical analysis.

HY-126829

Coumarin-SAHA
HDAC Cancer

Coumarin-SAHA is a fluorescent probe for determining the binding affinities (k_d) and the dissociation off-rates (k_off) of the HDAC8-inhibitor complexes.

Coumarin-SAHA	HDAC	Cancer
Coumarin-SAHA is a fluorescent probe for determining the binding affinities (k_d) and the dissociation off-rates (k_off) of the HDAC8-inhibitor complexes.

HY-W012642A

2-Aminopurine dihydrochloride	DNA Stain Others	Others
2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence.

HY-N2893

Cepharanone B
Aristolactam B II
Others Others

Cepharanone B is a fluorescent component isolated from the callus tissue of stephania cephaiuntha.

Cepharanone B Aristolactam B II	Others	Others
Cepharanone B is a fluorescent component isolated from the callus tissue of stephania cephaiuntha.

HY-P2550

β-Amyloid (1-40), FAM-labeled	Amyloid-β Others	Neurological Disease
β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λ_ex= 492 nm and λ_em= 518 nm).

HY-W277900

2-Methoxy-2,4-diphenylfuran-3-one	MMP	Cancer Inflammation/Immunology
2-Methoxy-2,4-diphenylfuran-3-one is a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and MMP-9 by zymography.

HY-147178

C-6 NBD-dihydro-Ceramide
Others Others

C-6 NBD-dihydro-Ceramide is a membrane-permeable ceramides. C-6 NBD-dihydro-Ceramide is a biologically active fluorescent analog of short chain.

C-6 NBD-dihydro-Ceramide	Others	Others
C-6 NBD-dihydro-Ceramide is a membrane-permeable ceramides. C-6 NBD-dihydro-Ceramide is a biologically active fluorescent analog of short chain.

HY-130017

HKSOX-1r (5/6-mixture)	Reactive Oxygen Species Others	Others
HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical.

HY-D1532

DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS	Others Parasite	Others
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite.

HY-110128

Sulfidefluor 7-AM
SF7-AM
Others Others

Sulfidefluor 7-AM is a stable hydrogen sulphide (H₂S) fluorescent probe.
HY-76981

5-Hydroxy-1-tetralone
Others Others

5-hydroxy-1-tetralone can be used as a fluorescent labeling reagent for the determination of glycosphingolipid from biological samples.

Sulfidefluor 7-AM SF7-AM	Others	Others
Sulfidefluor 7-AM is a stable hydrogen sulphide (H₂S) fluorescent probe.

5-Hydroxy-1-tetralone	Others	Others
5-hydroxy-1-tetralone can be used as a fluorescent labeling reagent for the determination of glycosphingolipid from biological samples.

HY-D1707

FDGlcU	Others	Others
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm).

HY-117468

Lissamine rhodamine B	Others	Others
Lissamine rhodamine B is a red-fluorescent dye, it is a derivative of rhodamine. Lissamine rhodamine B can be used as a fluorescent probe to develop competitive aptamer fluorescence anisotropy/polarization (FA/FP) assays.

HY-20803

2,3-Dihydroxyquinoxaline
Others Others

2,3-Dihydroxyquinoxaline is a fluorescent reagent. 2,3-Dihydroxyquinoxaline can be used for the determination of trace Pb(II) in vinegar.

2,3-Dihydroxyquinoxaline	Others	Others
2,3-Dihydroxyquinoxaline is a fluorescent reagent. 2,3-Dihydroxyquinoxaline can be used for the determination of trace Pb(II) in vinegar.

HY-D1460

Fluorescein Di-β-D-Glucuronide	Bacterial	Infection
Fluorescein Di-β-D-Glucuronide, a fluorescent probe, can be utilized to non-invasively image the intestinal bacterial β-glucuronidase activity in nude mice. Fluorescein Di-β-D-Glucuronide-based imaging reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, which would facilitate pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies.

HY-D1342

Coumberol
Others Cancer

Coumberol is a fluorescent substrate of AKR1C3 protein. Coumberol can be used for the research of AKR1C3.
HY-145882

BOD-NH-NP
Others Others

BOD-NH-NP is an activatable fluorescent probe for imaging endogenous nitric oxide via the eNOS enzymatic pathway.

Coumberol	Others	Cancer
Coumberol is a fluorescent substrate of AKR1C3 protein. Coumberol can be used for the research of AKR1C3.

BOD-NH-NP	Others	Others
BOD-NH-NP is an activatable fluorescent probe for imaging endogenous nitric oxide via the eNOS enzymatic pathway.

HY-151801

DIBA-Cy5	mAChR	Others
DIBA-Cy5 is a fluorescent DIBA antagonist made up be DIBA-alkyne binding Cyanine5 fluorophores (Cy5) and polyethylene glycol (PEG) biomolecules. DIBA-Cy5 can serve as a fluorescent ligand, suitable for probe attachment through click chemistry. DIBA-Cy5 exerts a high binding affinity to type-2 mAChR (M2R) with the K_d value of 1.80 nM, can directly stain M2R receptors in the sinoatrial node of a mouse heart.

HY-D1663

APTAB
Others Others

APTAB is a fluorescent cationic membrane probe. APTAB locates the anthracene-labeled molecules incorporated into model membranes by fluorescence quenching.

APTAB	Others	Others
APTAB is a fluorescent cationic membrane probe. APTAB locates the anthracene-labeled molecules incorporated into model membranes by fluorescence quenching.

HY-129811

Bis-ANS dipotassium	Microtubule/Tubulin	Neurological Disease
Bis-ANS dipotassium is a fluorescent probe of hydrophobic protein. Bis-ANS binds to tubulin with a K_d of 2 μM. Bis-ANS dipotassium is a potent biphasic modulator of protein liquid-liquid phase separation (LLPS). Bis-ANS dipotassium promotes LLPS at low concentrations but suppresses LLPS at high concentrations.

HY-135009

2-Di-1-ASP	G-quadruplex	Others
2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA.

HY-D0941

5-Carboxytetramethylrhodamine	Others	Others
5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm.

HY-D1441

Zinquin AM ester
Others Others

Zinquin AM ester is an AM ester form of Zinquin. Zinquin, a fluorescent dye, is a commonly used sensor for cellular Zn²⁺ status.

HY-D0115

7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester	DNA Stain Others	Others
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids.

HY-D1636

5-Nitro BAPTA	Others	Others
5-Nitro BAPTA is a calcium chelator, combinded with 2-Me-substituted TM ( as a fluorescent moiety), can be used to form a red fluorescent probe (CaTM-2 AM), for imaging of cytoplasmic Ca²⁺ in cultured living cells. 5-Nitro BAPTA is a building block used in the synthesis of Ca²⁺ specific chelators, Ca²⁺ buffers, and fluorescent Ca²⁺ indicators.

HY-W140203

2-(2′-Hydroxyphenyl)benzimidazole	Others	Others
2-(2′-Hydroxyphenyl)benzimidazole is some of the most extensively studied excited state intramolecular proton transfer (ESIPT) molecules exhibiting normal and tautomer emissions. 2-(2′-Hydroxyphenyl)benzimidazole has been applied as a fluorescent probe in various systems.

HY-109153

Nerindocianine	Others	Others
Nerindocianine is a fluorescent diagnostic contrast agent. Nerindocianine is highly hydrophilic and is primarily metabolized by the kidneys, allowing for a non-invasive intraoperative ureteral imaging.

HY-D1373

HBC	Others	Others
HBC is a green fluorescent protein (GFP) fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is used to detect RNA localization.

HY-147232

N-Acryloyl-1-pyrenebutylamine	Others	Others
N-Acryloyl-1-pyrenebutylamine is a potent fluorescent derivatization agent. N-Acryloyl-1-pyrenebutylamine combines with an alkyl-acrylamide side-chain to give fluorescence function on the polymer..

HY-141577

C12-NBD Sphinganine	Others	Others
C12-NBD Sphinganine is a fluorescent ceramidase substrate. C12-NBD Sphinganine can be used for the measurement of alkaline and neutral ceramidase activity from a variety of sources.

HY-137042

Cyanine5 alkyne Alkyne-Cy5	Mitochondrial Metabolism	Cancer
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC).

HY-W091541

4-Hydroxy-1H-indole-3-carbaldehyde 4-Hydroxyindole-3-carboxaldehyde	Others	Others
4-Hydroxy-1H-indole-3-carbaldehyde is a plant metabolite found in Capparis spinosa L.. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe.

HY-146343

BMI-Glu	Others	Cancer Inflammation/Immunology
BMI-Glu is a selective γ-glutamyl transpeptidase (GGT) fluorescent probe with a K_m of 69.63 µM. BMI-Glu has high sensitivity, good water solubility and biocompatibility.

HY-W003112

4-Fluororesorcinol
Others Others

4-Fluororesorcinol is a precursor used in the preparation of fluorescent dyes or indicators such as fluorescein, coumarin and resorcinol analogues.

HY-D1072

DiOC5(3) 3,3′-Dipentyloxacarbocyanine iodide	Others	Others
DiOC5(3) is the membrane potential (MP)-modifying fluorochrome. DiOC5(3) is an anti-LSC compound available for diagnostic imaging. DiOC5(3) has the advantage of being a single fluorescent chemical.

HY-D1674

Sulforhodamine G
Others Others

Sulforhodamine G is a fluorescent stain with broad dynamic ranges. Sulforhodamine G can be used for the research of protein stains.

HY-139646

KMG-104	Others	Neurological Disease
KMG-104 is a highly selective fluorescent Mg²⁺ probe. KMG-104 has been used widely and revealed Mg²⁺ mobilization in cytoplasm in various types of cells.

HY-D1609

BODIPY FL Verapamil hydrochloride	Others	Others
BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1.

HY-N6716

Filipin complex	Fungal Antibiotic	Infection
Filipin complex is a potent broad spectrum 28-membered ring pentaene macrolide antifungal antibiotic. Filipin complex is also a highly fluorescent polyene. Filipin complex specifically binds free cholesterol and is well established as a histochemical marker for the detection of unesterified cellular cholesterol. Filipin complex consists of four analogues (Filipins I-IV), with Filipin III (HY-N6718) comprising the bulk (>70%) of the complex.

HY-D1462

CellTracker Blue CMAC	Others	Others
CellTracker Blue CMAC is a fluorescent dye , whose chloromethyl group can form a covalent bond with cell proteins. CellTracker Blue CMAC providing a stable attachment permitting long-term cell tracking.

HY-147652

G-quadruplex DNA fluorescence probe 1	DNA Stain Others	Others
G-quadruplex DNA fluorescence probe 1 (Compound E1) is a selective G-quadruplex DNA targeting fluorescent probe. G-quadruplex DNA fluorescence probe 1 can pass through membrane and enter living cells with low cytotoxicity.

HY-D1697

OGDA
Others Infection

OGDA is a green fluorescent D-amino acid. OGDA is suitable for labeling peptidoglycan in Gram-positive and Gram-negative bacteria.

HY-D1597

Cyanine3.5 azide chloride	Others	Others
Cyanine3.5 azide chloride, an analog of Cyanine3.5 azide, is a potent green fluorescent dye. Cyanine3.5 azide chloride uses click chemistry to tag the ethylidene group. (λ_ex=591 nm, λ_em=604 nm).

HY-D1604

BODIPY FL Ethylamine	Others	Others
BODIPY FL Ethylamine is a fluorescent dye that reversibly reacts with aldehyde/ketone to yield a Schiff base. BODIPY FL Ethylamine can be reduced to form a stable amine derviative using sodium borohydride or sodium cyanoborohydride.

HY-W030319

Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate	Others	Others
Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, a natural coumarins derivative, is exploited for the synthesis of the switchable fluorescent substrates to be used in bacterial enzyme detection.

HY-D1677

5(6)-Carboxynaphthofluorescein	Others	Others
5(6)-Carboxynaphthofluorescein is a pH-dependent fluorophore. 5(6)-Carboxynaphthofluorescein shows good sensitivity in an alkaline pH range and it can be exploited in the construction of fiber-optic pH sensors. 5(6)-Carboxynaphthofluorescein can be used as a fluorescent pH indicator (Ex/Em=593/668 nm).

HY-113862

PHOME	Others	Others
PHOME is a fluorogenic substrate for sEH. sEH can hydrolyze the epoxy ring in the PHOME substrate. PHOME can be used for fluorescent epoxide hydrolase assay (extracted from patent CN113402447A).

HY-D0163

Methyl Green	DNA Stain Others	Others
Methyl Green is a potent fluorescent dye. Methyl Green is a DNA stains of cells and electrophoretic gels. Methyl Green can be used as a stain for direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm.

HY-147532

CB2R probe 1	Cannabinoid Receptor	Cancer
CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an K_i of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells.

HY-W110898

Nile blue chloride	Others	Others
Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics.

HY-D1694

LysoTracker Yellow HCK 123	Others	Others
LysoTracker Yellow HCK 123 is a potent yellow membrane-permeable fluorescent probe. LysoTracker Yellow HCK 123 is a weakly basic amine that selectively accumulates in cellular compartments with low luminal pH. (λ_ex=465 nm, λ_em=535 nm).

HY-D0950A

Methyl Green zinc chloride	DNA Stain Others	Others
Methyl Green zinc chloride is a potent fluorescent dye. Methyl Green zinc chloride is a DNA stains of cells and electrophoretic gels. Methyl Green zinc chloride can be used as direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm.

HY-D0050

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester	Others	Others
5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester (cDCFDASE) is a fluorescent probe. 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester can be used to evaluate the intracellular pH (pH_in) of living cells at a medium pH (pH_ex).

HY-145843

c-Myc inhibitor 5	c-Myc	Cancer
c-Myc inhibitor 5 (DA3) is a fluorescent, long chain-bridged bispurine that selectively targets the c-MYC G-quadruplex (K_D of 16 μM). c-Myc inhibitor 5 shows inhibition on c-MYC expression rather than other G4-driven oncogenes.

HY-139014

N-ε-propargyloxycarbonyl-L-lysine H-L-Lys(Poc)-OH	Others	Cancer
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals.

HY-133821

N-Methylmesoporphyrin IX	G-quadruplex	Neurological Disease
N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies.

HY-D1637

5-Nitro BAPTA tetramethyl ester	Others	Others
5-Nitro BAPTA tetramethyl ester is a calcium chelator. 5-Nitro BAPTA tetramethyl ester involves in the two-photon probe synthesis, and is used for real-time imaging of intracellular calcium ions, calcium waves monitoring at a depth of 100-300 μm in liver tissues for 1100-4000 s. 5-Nitro BAPTA tetramethyl ester, together with fluorescent compound 2-Me-substituted TM, can be used to form a red fluorescent probe (CaTM-2 AM).

HY-131026

Janelia Fluor® 635, SE JF635, SE; JF635, NHS	Others	Others
Janelia Fluor® 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-123633

4-Methylumbelliferyl β-D-Glucopyranoside	Glucosidase Others	Others
4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity. 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.

HY-124473

Naphthofluorescein Naphthafluorescein	HIF/HIF Prolyl-Hydroxylase	Cancer
Naphthofluorescein inhibits the interaction between HIF-1 and Mint3. Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo. Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging.

HY-136214

R-BC154 acetate	Integrin	Cancer Inflammation/Immunology
R-BC154 acetate is a selective fluorescent α₉β₁ integrin antagonist. R-BC154 acetate acts as a useful high affinity, activation dependent integrin probe, which can be used to investigate α9β1 and α4β1 integrin binding activity.

HY-D1425

DCVJ 9-(2,2-Dicyanovinyl)julolidine	Others	Others
DCVJ (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. DCVJ also binds to phospholipid bilayers and increases its fluorescence intensity. DCVJ can detect the kinetic process of degranulation of mast cells.

HY-100512

Benzenepentacarboxylic Acid
Pentacarboxybenzene
Reactive Oxygen Species Others Others

Benzenepentacarboxylic acid (BA), a novel fluorescent probeas to detect and scavenge HO-.

HY-119437

FLTX1	Estrogen Receptor/ERR	Cancer
FLTX1 is a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus.

HY-D1528

MTSEA-Fluorescein
Sodium Channel Neurological Disease

MTSEA-Fluorescein is a fluorescent probe that can be used for ion channel research.

HY-100575

Acriflavine Acriflavinium chloride 3,6-Acridinediamine mix	HIF/HIF Prolyl-Hydroxylase	Cancer Infection
Acriflavine is a fluorescent dye for labeling high molecular weight RNA. It is also a topical antiseptic.

HY-142521

BLT2 probe 1	Leukotriene Receptor	Metabolic Disease
BLT2 probe 1 (compound 13) is a fluorescent probe based on the synthetic BLT2 agonist CAY10583. BLT2 is a promising target for diabetic wound healing and gastrointestinal lesions. BLT2 probe 1 is suitable to investigate the pharmacology of BLT2 receptor ligands in a variety of assay systems.

HY-101879

Acridine Orange hydrochloride	DNA Stain Parasite	Others
Acridine Orange hydrochloride is a cell-permeable fluorescent dye that binds to nucleic acids, resulting in an altered spectral emission.

HY-123533

Resorufin
NSC 12097
Reactive Oxygen Species Others

Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte.

HY-123533A

Resorufin sodium salt NSC 12097 sodium salt	Reactive Oxygen Species	Others
Resorufin sodium salt (NSC 12097 sodium salt) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte.

HY-111391

Resazurin sodium Diazoresorcinol sodium	Bacterial	Others
Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.

HY-D0149

4-(Trifluoromethyl)umbelliferone
Cytochrome P450 Others

4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes.

HY-112636

Astrophloxine	Amyloid-β Others	Others
Astrophloxine is a fluorescent imaging probe capable of targeting antiparallel dimers. Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal fluid samples of Alzheimer's disease (AD) mice.

HY-D0021

Ethidium bromide EtBr; Homidium bromide	DNA Stain Others	Others
Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

HY-15943

6-TAMRA 6-Carboxytetramethylrhodamine	DNA Stain Others	Others
6-TAMRA has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry.

HY-D0814

DAPI dihydrochloride 4',6-Diamidino-2-phenylindole dihydrochloride	DNA Stain Others	Others
DAPI dihydrochloride (4',6-diamidino-2-phenylindole) is a fluorescent stain by binding in the minor grove of A-T rich sequences of DNA.

HY-D1086

6-Carboxy-X-rhodamine, succinimidyl ester 6-ROX, SE	DNA Stain Others	Others
6-Carboxy-X-rhodamine, succinimidyl ester (6-ROX, SE) is a fluorescent dye for oligonucleotide labeling and automated DNA sequencing.

HY-101859

NucPE1 Nuclear Peroxy Emerald 1	Reactive Oxygen Species	Others
NucPE1 (Nuclear Peroxy Emerald 1) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.

HY-D1159

HKOH-1r
Reactive Oxygen Species Others Others

HKOH-1r is a highly sensitive and selective fluorescent probe which is used for detecting endogenous hydroxyl radicals in living cells.
HY-102055

JAK2 JH2 Tracer
JAK Others

JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a K_d of value 0.2 μM.

HY-131007

FFN270 hydrochloride	Adrenergic Receptor	Metabolic Disease
FFN270 hydrochloride, a fluorescent tracer of norepinephrine, is a fluorescent substrate of the norepinephrine and vesicular monoamine transporters. FFN270 hydrochloride exhibits two resolved absorption/excitation maxima depending on solvent pH (FFN270 ex: 320 nm or 365 nm, em: 475 nm) and can function as ratiometric fluorescent pH-sensors.

HY-D1376A

Sulfo-Cyanine5.5 amine	Others	Others
Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling.

HY-D1494

FSB	Amyloid-β	Neurological Disease
FSB is a fluorescent dye that can be used to detect filamentous tau and to label human amyloid lesions with high sensitivity and specificity (excitation: 390 nm, emission: 520 nm).

HY-D1606

BODIPY FL prazosin	Adrenergic Receptor	Metabolic Disease
BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with K_i values of 14.5, 43.3 nM for α1a-AR and α1b-AR, respectively. BODIPY FL prazosin also is a fluorescent ligand with the excitation and emission wavelengths are 485 and 535 nm, respectively. BODIPY FL prazosin can be used for study the differences in the subcellular localization of α1-adrenoceptor subtypes.

HY-D1521

N-(NBD-Aminolauroyl)safingol
Others Others

N-(NBD-Aminolauroyl)safingol is a fluorescent group.
HY-139816

BTNPO
Others Neurological Disease

BTNPO is a unimolecular two-photon fluorescent probe.

HY-B1422

9-Aminoacridine Aminacrine	HIV Bacterial	Cancer Infection
9-Aminoacridine (Aminacrine) is a highly fluorescent dye used as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator. 9-Aminoacridine is an effective antibacterial agent with caries-disclosing features.

HY-144603

Neuropeptide Y Y1 receptor antagonist 1	Neuropeptide Y Receptor	Neurological Disease
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, is a potent antagonist of neuropeptide Y Y¹ receptor (Y¹R), with a K_i of 0.19 nM.

HY-D1493

FIM-1	PKC	Others
FIM-1 is a fluorescent PKC (protein kinase C) probe that can be used for mitochondrial staining. FIM-1 inhibits PKC and acts as ATP-competitive catalytic site inhibitor.

HY-133705

Geldanamycin-FITC	HSP	Others
Geldanamycin-FITC, a Geldanamycin fluorescent probe, can be used in a fluorescence polarization assay for HSP90 inhibitors. Geldanamycin-FITC also can be used for detection of cell surface HSP90.

HY-D1116

MitoMark Red I	Others	Others
MitoMark Red I is a fluorescent mitochondrial marker. MitoMark Red I is a red fluorescent dye which accumulates in mitochondria in viable cells and has an excitation wavelength of 578 nm and emission of 599 nm.

HY-15559A

Hoechst 33342 trihydrochloride bisBenzimide H 33342 trihydrochloride; HOE 33342 trihydrochloride	Autophagy	Others
Hoechst 33342 trihydrochloride is a membrane permeant blue fluorescent DNA stain.

HY-P1003

Ac-DEVD-AMC
Caspase Cancer

Ac-DEVD-AMC is the Caspase-3 fluorescent substrate.

HY-145493

C12 NBD Galactosylceramide	Others	Others
C12 NBD galactosylceramide, fluorescent dye, is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide can be used for the research of imaging.

HY-D0079

Dihydroethidium Hydroethidine; PD-MY 003	Reactive Oxygen Species	Others
Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red (Ex/Em=518/616 nm).

HY-D1523

Z-Arg-Arg-4MβNA triacetate	Cathepsin	Others
Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λ_ex = 355 nm, λ_em = 430 nm).

HY-126793

2′,7′-Dichlorofluorescein diacetate DCFH2-DA	Reactive Oxygen Species Others	Others
2′,7′-Dichlorofluorescein diacetate (DCFH-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon.

HY-151536

meso-Benzothiazole-BODIPY 505/515
Others Neurological Disease

meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probe
HY-15560

Hoechst 34580
HOE 34580
Amyloid-β Neurological Disease

Hoechst 34580 is a cell-permeable fluorescent dye for staining DNA and nuclei.
HY-D1021

AA-dUTP sodium salt
Aminoallyl-dUTP sodium salt
DNA/RNA Synthesis Others

AA-dUTP sodium salt is a fluorescent dye which can be used to stain cDNA.

HY-D1022A

Biotin-16-dUTP trisodium Biotin-16-deoxyuridine-5'-triphosphate trisodium	DNA Stain Others	Others
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications.

HY-15560B

Hoechst 34580 tetrahydrochloride HOE 34580 tetrahydrochloride	Amyloid-β	Neurological Disease
Hoechst 34580 tetrahydrochloride is a cell-permeable fluorescent dye for staining DNA and nuclei.

HY-15622

meta-iodoHoechst 33258
DNA Stain Others Cancer

Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.
HY-15629

HOE 32020
DNA Stain Others Others

HOE 32020 is a Hoechst stain, which is a blue fluorescent dyes used to stain DNA.
HY-Y1309

1-Naphthol
Furro ER; NSC 9586; Nako TRB
Endogenous Metabolite Others

1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe.

HY-W356116

C6 NBD Ceramide	Others	Others
C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism.

HY-W402148

10-Methyl-9-(phenoxycarbonyl)acridinium (fluorosulfonate)	ROS Kinase	Others
10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate, a phenyl ester of acridinium esters, is a fluorescent dye that produces chemiluminescent under neutral conditions. 10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate can be used for the measurement of hydrogen peroxide.

HY-D1156A

HKSOX-1m (5/6-mixture) (hydrobromide)	Reactive Oxygen Species Others	Others
HKSOX-1m (5/6-mixture) hydrobromide is a O₂^•− fluorescent probe for mitochondria-targeting, exhibiting excellent selectivity and sensitivity toward O₂^•− over a broad range of pH, strong oxidants, and abundant reductants found in cells.

HY-15625

Hoechst 33258 analog 3
DNA Stain Others Others

Hoechst 33258 analog 3 are part of a family of blue fluorescent dyes used to stain DNA.
HY-100335

PCI-33380
Btk Others

PCI-33380 is an irreversible and selective Bruton's Tyrosine Kinase (BTK) inhibitor (fluorescent probe).
HY-18675

IQ-R
Others Others

IQ-R is a novel hypoxia-sensitive fluorescent probe, consisting of an indolequinone unit and a rhodol fluorophore.
HY-123495

CRANAD-28
Others Neurological Disease

CRANAD-28 is a robust fluorescent compound for visualization of amyloid beta plaques.
HY-15624

Hoechst 33258 analog 2
DNA Stain Cancer

Hoechst 33258 analog 2 are part of a family of blue fluorescent dyes used to stain DNA.
HY-D1395

RH-EDA
Reactive Oxygen Species Others Others

RH-EDA is a rhodamine-based turn-on fluorescent probe for detecting hydroxyl radicals in living systems.

HY-D0055

3-Cyano-7-ethoxycoumarin	Cytochrome P450	Others
3-Cyano-7-ethoxycoumarin is a fluorogenic cytochrome P-450 substrate that generates blue fluorescent product upon enzyme cleavage Target: Cytochrome P450 3-Cyano-7-ethoxycoumarin is a fluorescent probe useful in microsomal dealkylase studies.

HY-141667

MBD 7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole	Others	Others
MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule.

HY-W042853

N-(2-Hydroxyethyl)-2-phenylacetamide
Others Others

N-(2-Hydroxyethyl)-2-phenylacetamide is a fluorescent dye.
HY-D1253

TP-TRFS
Others Neurological Disease

TP-TRFS is a highly selective and the first two-photon fluorescent probe of thioredoxin reductase (TrxR).
HY-119395B

Kynuramine dihydrochloride
Monoamine Oxidase Metabolic Disease

Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase.
HY-D1399

Kdn probe-1
Others Others

Kdn probe-1 is a fluorescent Kdn probe and reveals the localization of AfS in vesicles at the cell surface.

HY-16045

Hexaminolevulinate hydrochloride Hexyl 5-aminolevulinate hydrochloride; P-1206; 5-Aminolevulinic acid hexyl ester hydrochloride	Others	Cancer
Hexaminolevulinate hydrochloride is a fluorescent agent, and can be used with a light test to check for bladder cancer.

HY-D1584

C12 NBD Sphingomyelin	Phospholipase	Others
C12 NBD sphingomyelin is an active derivative of sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm).

HY-130913

5-FAM-Alkyne
Phosphatase Others

5-FAM-Alkyne is a high selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP).
HY-128919

Ac-Lys-AMC
HDAC Others

Ac-Lys-AMC (Hexanamide), also termed MAL, is a fluorescent substrate for histone deacetylase HDACs.

HY-W011664

1,3-Diphenylisobenzofuran DPBF	Reactive Oxygen Species	Others
1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe which possesses a highly specific reactivity towards singlet oxygen (¹O₂) forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran can detect the generation of reactive oxygen species (ROS).

HY-D1156

HKSOX-1m (5/6-mixture)	Reactive Oxygen Species Others	Others
HKSOX-1m (5/6-mixture) is a O₂^•− fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O₂^•− over a broad range of pH, strong oxidants, and abundant reductants found in cells.

HY-W012642

2-Aminopurine	DNA Stain Others	Others
2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics.

HY-D0113

7-Hydroxy-4-methyl-2(1H)-quinolone	Reactive Oxygen Species Others	Others
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage.

HY-W441022

DSPE-Rhodamine
Others Others

DSPE-Rhodamine is a Rhodamine B labeled phophalipid DSPE. DSPE-Rhodamine can be used for the preparation of fluorescent labeling liposomes.
HY-D1481

6,7-Diaminoquinoxaline-2,3-dione dihydrochloride
Others Others

6,7-Diaminoquinoxaline-2,3-dione dihydrochloride is a fluorescent dye that reacts with aldehydes.
HY-D0832

CY5-N3
Sulfo-Cyanine5-azide
DNA Stain Others Others

CY5-N3 is a Cy5-azide, which is a fluorescent dye.
HY-P1093

Ac-LEHD-AFC
Caspase Others

Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase.
HY-119287

TSQ
Others Others

TSQ is a fluorescent sensor for cellular zinc, can image zinc proteins (λ_max~470 nm).

HY-103336

Tocrifluor 1117 T1117	GPR55 Cannabinoid Receptor	Cardiovascular Disease
Tocrifluor 1117 (T1117), a fluorescent form of the cannabinoid CB1 receptor antagonist AM251 (HY-15443), is a selective fluorescent GPR55 ligand. Tocrifluor 1117 is a potent tool for identifying the cellular location of cannabinoid receptors (including GPR55 in living tissues) (Ex/Em=543/590 nm).

HY-15628

Hoechst 33258 analog 5
DNA Stain Others Others

Hoechst 33258 analog 5 is a analog of Hoechst stains, which are part of a family of blue fluorescent dyes used to stain DNA.

HY-139101

Guanosine 5'-triphosphate-5'-adenosine GpppA	Endogenous Metabolite DNA/RNA Synthesis	Others
Guanosine 5'-triphosphate-5'-adenosine, the 5′ cap analog, is a fluorescent substrate analog.

HY-D1157

HKPerox-2	Reactive Oxygen Species	Others
HKPerox-2 is an excellently selective and sensitive green fluorescent probe toward H₂O₂ over 30-fold other tested ROS/RNS in chemical and biological systems. HKPerox-2 is a O-methyl rhodol derivative and specifically recognize H₂O₂ based on a tandem payne/dakin reaction.

HY-W247098

Dihydrorhodamine 6G DHR 6G	Reactive Oxygen Species	Cancer
Dihydrorhodamine 6G (DHR 6G) is the reduced form of Rhodamine 6G, which is used as fluorescent mitochondrial dye. It is nonfluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 6G that accumulates in mitochondrial membranes. Dihydrorhodamine 6G is useful for detecting reactive oxygen species (ROS) including superoxide.

HY-23926

PYBG
Others Others

PYBG acts as a versatile precursor to be facilely conjugated with various fluorescent dyes through ‘Click chemistry’ and Sonogashira coupling reactions.
HY-133884

ICG-amine
Others Cancer

ICG amine, as a near-infrared fluorescent probe, binds to amino acid residues without condensing agents. ICG is a tricarbocyanine dye.
HY-D0043

5(6)-ROX
5(6)-Carboxy-X-rhodamine
DNA Stain Others Others

5(6)-ROX is a nucleic acid fluorescent label which can be used as a reference dye for real-time polymerase chain reaction.

HY-D1301

BODIPY 581/591 C11	Ferroptosis	Cancer Metabolic Disease Inflammation/Immunology
C11-BODIPY581/591 is a fluorescent ratio-probe of lipid oxidation. C11-BODIPY581/591 is often used for indexing lipid peroxidation and antioxidant efficacy in model membrane systems and living cells. C11-BODIPY581/591 is applied in the quantitation of ferroptosis.

HY-143218

TPE-MI Tetraphenylethene maleimide	Huntingtin Parasite	Neurological Disease
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells. TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin treatment of the malaria parasitesPlasmodium falciparum .

HY-D0129

8-Methoxypyrene-1,3,6-trisulfonate trisodium
MPTS
Others Others

8-Methoxypyrene-1,3,6-trisulfonate trisodium (MPTS) is a highly water-soluble superpolar fluorescent probe.

HY-P1459

Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)	Bacterial	Infection
Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.

HY-D1569

CellTracker Orange CMRA Dye	Others	Others
CellTracker Orange CMRA Dye is a fluorescent dye. CellTracker Orange CMRA Dye can be used for cell imaging and monitoring the movement and location of cells.

HY-D0971

Pyronin Y Pyronine G; C.I. 45005	DNA Stain Others	Others
Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells.

HY-W140535

Tetrasodium,4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II))	Others	Others
Tetrasodium,4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II)) is a luminescent indicator dye.

HY-100857

PrPSc-IN-1	Others	Neurological Disease
PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrP^Sc, inhibits its accumulation, with an IC₅₀ of 1.6 μM. Anti-prion activity.

HY-115640

TRFS-green	Others	Others
TRFS-green is a highly selective off−on fluorescent probe for imaging thioredoxin reductase (TrxR) in living cells. TRFS-green has the maximum absorbance at around 373 nm.

HY-D1576

C6 NBD L-threo-dihydroceramide	Others	Others
C6 NBD L-threo-dihydroceramide is a dihydro-ceramide isomer labeled with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD), can be used to detect ceramide.

HY-W142117

H-Asp(AMC)-OH
Others Others

H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM.
HY-D1400

HBTP-H2S chloride
Others Others

HBTP-H2S (chloride) is a NIR fluorescent probe for in situ bioimaging of endogenous H2S in rice roots under Al ³⁺ and flooding stresses.
HY-W248594

IR 813 tosylate
Others Others

IR 813 tosylate is a near-infrared (NIR) fluorescent dye (λ_ex=815 nm, λ_em=840 nm) and can be used for visualizing regional lymph nodes in mice.

HY-103240

Methoxy-X04	Amyloid-β	Others
Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques.

HY-P1853

Abz-FR-K(Dnp)-P-OH	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Abz-FR-K(Dnp)-P-OH is an angiotensin I-converting enzyme (ACE) substrate and an internally quenched fluorogenic substrate for real time fluorescent assay.

HY-120870

para-Nitroblebbistatin	Myosin	Metabolic Disease
para-Nitroblebbistatin is a non-cytotoxic, photostable, fluorescent and specific Myosin II inhibitor, usd in the study of the specific role of myosin II in physiological, developmental, and cell biological studies.

HY-108715A

RT-AM	Others	Neurological Disease
RT-AM is a pro-drug real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.

HY-D1398

LtIA-F	nAChR	Neurological Disease
LtIA-F, a novel fluorescent analogue of LtIA, provides a wealth of pharmacological tools to explore the structure–function relationship, distribution, and ligand binding domain of the α3β2 nAChR subtype.

HY-111945

Cys modifier 1	Others	Others
Cys modifier 1 (compound 7) is a cysteine-selective protein modifier for protein bioconjugation. A fluorescent carbonylacrylic derivative bearing nitrobenzofurazan (λ_ex=465nm and λ_em539 nm)_[1].

HY-13615A

EC-17 disodium salt	Others	Cancer
EC-17 (disodium salt) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The peak excitation and emission wavelengths of EC-17 are 470/520 nm.

HY-D0039

3-Cyanoumbelliferone	Macrophage migration inhibitory factor (MIF) Others	Others
3-Cyanoumbelliferone is a coumarin derivative, acting as molecular probe and fluorescent dye. 3-Cyanoumbelliferone is also a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a K_i of 2.9 μM.

HY-D1117

NADA-green NADA hydrochloride	Others	Infection
NADA-green is a fluorescent D-amino acid probe. NADA-green is efficiently incorporated into the peptidoglycan of diverse bacterial species peptidoglycan biosynthesis. NADA-green allows probing of bacterial growth with minimal perturbation.

HY-46317

DMT-5Me-dC(Bz)-CE Phosphoramidite	DNA Stain Others	Others
DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding.

HY-D0895

3,4,5,6-Tetrabromophenolsulfonephthalein
Others Others

3,4,5,6-Tetrabromophenolsulfonephthalein is a stain for cell biology.

HY-123533S

Resorufin-d6 NSC 12097-d6	Reactive Oxygen Species	Others
Resorufin-d6 (NSC 12097-d6) is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte.

HY-103242

CRANAD-2	Amyloid-β	Neurological Disease
CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a K_d of 38 nM.

HY-131006

FFN200 dihydrochloride	Monoamine Transporter	Neurological Disease
FFN200 dihydrochloride, a fluorescent substrate of VMAT2, selectively trace monoamine exocytosis in both neuronal cell culture and brain tissue. The fluorescence excitation and emission maxima of FFN200 are determined to be 352 and 451 nm, respectively.

HY-D1246

Ethidium monoazide bromide	DNA Stain	Others
Ethidium monoazide bromide is a DNA intercalating fluorescent dye that enters bacteria with damaged membranes. Ethidium monoazide bromide can be covalently linked to DNA by photoactivation. Ethidium monoazide bromide stains only dead cells.

HY-D0049

6-TAMRA-SE 6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester	DNA Stain Others	Others
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing.

HY-102034

Complement factor D-IN-1	Complement System	Inflammation/Immunology
Complement factor D-IN-1 is a potent and selective small-molecule reversible factor d inhibitor, with IC₅₀s of 0.006 and 0.05 μM in FD Thioesterolytic Fluorescent Assay and a MAC Deposition Assay, respectively.

HY-D0054

9-(2-Carboxy-2-cyanovinyl)julolidine	Others	Inflammation/Immunology
9-(2-Carboxy-2-cyanovinyl)julolidine is a fluorescent molecular rotor. 9-(2-Carboxy-2-cyanovinyl)julolidine can be used to bind to IgG and Fab, and preparing antibodies.

HY-P2267

LDV
Integrin Others

LDV, a tripeptide, is a non-fluorescent analog of LDV-FITC. LDV is a α4β1 integrin (VLA-4) ligand, and binds α4β1 integrin in leukemia cells.

HY-121271

Kadsurin	Others	Inflammation/Immunology
Kadsurin, a natural compound from the stems of Kadsura heteroclita (Schizandraceae), results in significant decreases of CCL₄- induced lipid-peroxidation products, such as thiobarbituric acid reactive substances (TBA-RS), conjugated dienes and fluorescent products in the liver of mice.

HY-131008

Fluorescein tyramide	Others	Others
Fluorescein tyramide is a green *fluorescent* reagent (λ_abs: 494 nm; λ_em: 517 nm). Fluorescein tyramide is widely used for tyramide signal amplification (TSA) with a low-abundance in IHC, ICC, in situ hybridization (FISH) and flow cytometry (FCM) applications.

HY-D1443

BSB (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene	Amyloid-β	Others
BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease.

HY-N0188

Esculin	p38 MAPK	Inflammation/Immunology Cancer
Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway.

HY-D1510

4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside	Others	Others
4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety.

HY-D0952

Acridine Orange base	Others Parasite	Others
Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays.

HY-118581

Coralyne chloride	Topoisomerase	Cancer
Coralyne chloride is a protoberberine alkaloid with potent anti-cancer activities. Coralyne chloride acts as a potent topoisomerase I poison and induces Top I mediated DNA cleavage. Coralyne chloride can be used for preparing coralyne derivatives as DNA binding fluorescent probes.

HY-W278706

N-[4-(2-Benzimidazolyl)phenyl]maleimide	Others	Others
N-[4-(2-Benzimidazolyl)phenyl]maleimide is a potent fluorescent probe with excitation maximum of 315 nm and emission maximum of 360 nm. N-[4-(2-Benzimidazolyl)phenyl]maleimide can be used for fluorometry of thiol compounds.

HY-114227

Hexidium iodide	DNA Stain Others	Inflammation/Immunology
Hexidium iodide, a fluorescent nucleic binding acid stain (excitation/emission ~ 518/600 nm), permeants to mammalian cells and selectively stains almost all gram-positive bacteria. Hexidium iodide can bind to the DNA of all bacteria after permeabilization by EDTA.

HY-D1333

BDP 630/650 alkyne	Others	Others
DP 630/650 alkyne is a red fluorescent dye with λ_excitation of 630 nM and λ_emission of 650 nM. The terminal alkyne group can be conjugated with various azides by copper catalyzed Click chemistry. BDP 630/650 alkyne can be used for fluorescence polarization assays.

HY-151109

IR-990	Others	Others
IR-990 is an activatable *NIR-II fluorescent* probe** with an acceptor-π-acceptor (A-π-A) skeleton for real-time detection of H₂O₂ in vivo. IR-990 is a powerful diagnosis of drug-induced liver injury (DILI).

HY-131045

HADA hydrochloride HCC-Amino-D-alanine hydrochloride	Bacterial	Infection
HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λ_em~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation.

HY-D1020

7-Aminoactinomycin D 7-AAD	DNA/RNA Synthesis Bacterial DNA Stain Antibiotic	Cancer Infection
7-Aminoactinomycin D (7-AAD) a fluorescent DNA stain, is a potent RNA polymerase inhibitor. 7-Aminoactinomycin D selectively binds to GC regions of the DNA. 7-Aminoactinomycin D also has antibacterial effects.

HY-128676

N-ε-propargyloxycarbonyl-L-lysine hydrochloride H-L-Lys(Poc)-OH hydrochloride	Others	Cancer
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals.

HY-111661

6,7-Dimethyl-8-ribityllumazine	Others	Others
6,7-Dimethyl-8-ribityllumazine is a direct biosynthetic precursor of Riboflavin (RBF; HY-B0456). 6,7-Dimethyl-8-ribityllumazine is a noncovalently bound fluorophore of Lumazine protein (LumP), which is a fluorescent accessory protein.

HY-134564

Fluorescein octadecyl ester	Others	Others
Fluorescein octadecyl ester is a lipophilic fluorescent reagent is immobilized in a plasticized PVC membrane. Fluorescein octadecyl ester can reversibly recognize alcohol molecules and can be used to determine the concentration of ethanol in alcoholic drinks. Fluorescein octadecyl ester can be used as acceptor to make optrode membrane for the determination of picric acid.

HY-126823

Phen Green SK diacetate PGSK diacetate	Others	Others
Phen green SK (PGSK) diacetate is a fluorescent heavy metal indicator that reacts with a variety of metal ions, including Fe2+, Cd2+, Co2+, Ni2+, Zn2+. PGSK diacetate displays excitation/emission maxima of 507/532 nm, respectively, and fluorescence is quenched upon interaction with metal ions

HY-D0031

8-Aminopyrene-1,3,6-trisulfonic acid trisodium APTS	Others	Others
8-Aminopyrene-1,3,6-trisulfonic acid trisodium is a water-soluble anionic fluorescent dye. The fluorescence intensity of 8-Aminopyrene-1,3,6-trisulfonic acid trisodium remains nearly constant over a pH range from 4 to 10.

HY-147738

SQM-NBD	Others	Others
SQM-NBD is a potent and selectiveAIE fluorescent probe. SQM-NBD exhibits excellent sensitivity to Cys and Hcy with the LOD of 54 nM and 72 nM, respectively.SQM-NBD has good cell permeability and low cytotoxicity. SQM-NBD has the potential for Cys/Hcy identification under physiological and pathological conditions.

HY-D1710

Anti-α-Tubulin Antibody, AF555 conjugate	Microtubule/Tubulin	Others
Anti-α-Tubulin Antibody, AF555 conjugate is a conjugate of mouse anti-α-tubulin monoclonal antibody and the red fluorescent dye Alexa Fluor 555. Anti-α-Tubulin Antibody, AF555 conjugate can be used for the detection of tubulin (Ex/Em: 554/567 nm).

HY-D1341

Coumberone	Others	Cancer
Coumberone is a metabolic fluorogenic probe, and isoform-selective substrate for all AKR1C isoforms. Coumberone can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone can be used for the research of AKR1C.

HY-118135

4-Methylumbelliferyl-α-D-galactopyranoside 4MU-α-Gal	Others	Others
4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA.

HY-120972

Pentafluorobenzenesulfonyl fluorescein	Others	Others
Pentafluorobenzenesulfonyl fluorescein is a H₂O₂-selective sensor that can be used to detect H₂O₂ levels in cells. Pentafluorobenzenesulfonyl fluorescein is normally non-fluorescent but fluoresces upon perhydrolysis of the sulfonyl linkage by H₂O₂.

HY-147541

A2A/A3 AR antagonist-1	Adenosine Receptor	Inflammation/Immunology
A2A/A3 AR antagonist-1 (compound 23) is a dual A_2A/A₃ adenosine receptor (AR) fluorescent ligand, with K_is of 90 nM and 31.8 nM for hA_2A AR and hA₃ AR, respectively.

HY-D0142

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium	Others	Others
Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO₂ release.

HY-D1078

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate	Reactive Oxygen Species	Others
5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a cell permeant fluorescent indicator. 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate can be used to assess reactive oxygen species (ROS) generation within human neuronal-glial (HNG) cells in primary co-culture

HY-133535

PA Janelia Fluor® 646, SE PA-JF646-NHS	Others	Others
PA Janelia Fluor® 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag^® and SNAP-tag^®. PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λ_{Excitation/emission}~650/664 nm). Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-N2011

Octyl gallate n-Octyl gallate; Stabilizer GA 8	Bacterial HSV Influenza Virus Reactive Oxygen Species	Infection
Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity. Octyl gallate (Progallin O) shows selective and sensitive fluorescent property. Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus.

HY-131010

Flutax-2 (5/6-mixture)	Microtubule/Tubulin	Cancer
Flutax-2 (5/6-mixture) is an active fluorescent derivative of Taxol. Flutax-2 (5/6-mixture) binds to polymerized α,β-tubulin dimers. Flutax-2 (5/6-mixture) is able to stabilize microtubules of intact T. gallinae and T. foetus trophozoites^[1].

HY-149028

Mem-C1C18	Others	Others
Mem-C1C18 is a polarity-sensitive fluorescent probe with excellent plasma membrane anchoring, high brightness and a sensitive response to environmental polarity by altering the fluorescence lifetime. Mem-C1C18 can be used to quantify changes in the polarity of the plasma membrane during iron death.

HY-W088075

Acriflavine hydrochloride Acriflavinium chloride hydrochloride	HIF/HIF Prolyl-Hydroxylase Bacterial SARS-CoV	Cancer Infection
Acriflavine hydrochloride (Acriflavinium chloride hydrochloride) is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine hydrochloride is an antiseptic. Acriflavine hydrochloride is a potent HIF-1 inhibitor, with antitumor activity. Acriflavine hydrochloride has antimicrobial and antiviral activities. Acriflavine hydrochloride is a potent papain-like protease (PL^pro) inhibitor, which inhibits SARS-CoV-2

HY-147181

1,3-Di-(2-pyrenyl)propane	Others	Others
1,3-Di-(2-pyrenyl)propane is a fluorescent indicator. 1,3-Di-(2-pyrenyl)propane can be used in fluidity of bacterial membrane lipids monitored by intramolecular excimerization. 1,3-Di-(2-pyrenyl)propane shows temperature dependence of fluorescence lifetime distributions.

HY-D0128

4-Methylherniarin 7-Methoxy-4-methylcoumarin	Bacterial	Infection
4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC₅₀ values of 11.76 μg/ml and 13.47 μg/ml.

HY-120659

Gly-Gly-AMC
Others Others

Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus.

HY-115980

Anticancer agent 39	Apoptosis	Cancer
Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC₅₀ value of 0.39 μM.

HY-103465

FFN511	Monoamine Transporter	Others
FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2). FFN511 inhibits serotonin binding to VMA T2-containing membranes with an IC₅₀ of 1 µM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices.

HY-118411

5-Ethynyl-2'-deoxyuridine	PROTAC Linkers	Cancer
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation. 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-130851

HS-27	HSP	Cancer
HS-27, a fluorescently-tethered Hsp90 inhibitor, assays surface Hsp90 expression on intact tissue specimens. HS-27 is made up of the core elements of SNX-5422, an Hsp90 inhibitor, tethered via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC), that binds to ectopically expressed Hsp90. HS-27 has potential use in a see-and-treat paradigm in breast cancer.

HY-151728

Trisulfo-Cy3-Alkyne	Others	Others
Trisulfo-Cy3-Alkyne is a water soluble cyanine linker containing an alkyne group, which enables Click Chemistry to attach trisulfo-Cy3 to various azide-bearing molecules. Trisulfo-Cyanine3 is a fluorophore which is compatible with a wide range of fluorescent scanners, imagers, microscopes, etc. It is a bright and photostable dye and can be easily detected in gels by naked eye in low amounts (nmol). Reagent grade, for research use only.

HY-116141

7-Hydroxycoumarinyl arachidonate 7-HCA; Umbelliferyl Arachidonate; 7-HC-arachidonate	Phospholipase MAGL	Others
7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC; HY-N0573). Release of 7-HC can be measured using a fluorometer.

HY-D1551

10-(4-(Bis(2-hydroxyethyl)amino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide	Others	Others
10-(4-(Bis(2-hydroxyethyl)amino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide, a BODIPY derivative, is a fluorescent indicator for detecting Pb²⁺ (Ex=504 nM, Em=510 nM).

HY-146578

Keap1-Nrf2-IN-8	Keap1-Nrf2	Inflammation/Immunology
Keap1-Nrf2-IN-8 (compound 12d) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein−protein interaction) inhibitor with IC₅₀s of 64.5 nM and 14.2 nM for FP and TR-FRET assays, respectively. Keap1-Nrf2-IN-8 significantly increases the mRNA levels of Nrf2 downstream genes, GSTM3, HMOX2 and NQO1.

HY-138097

α-NETA	Aldehyde Dehydrogenase (ALDH) Cholinesterase (ChE) Apoptosis	Cancer
α-NETA is a potent and noncompetitive choline acetyltransferase (ChA) inhibitor with an IC₅₀ of 9 μM. α-NETA is a potent ALDH1A1 (IC₅₀=0.04 µM) and chemokine-like receptor-1 (CMKLR1) antagonist. α-NETA weakly inhibits cholinesterase (ChE; IC₅₀=84 µM) and acetylcholinesterase (AChE; IC₅₀=300 µM). α-NETA has anti-cancer activity.

HY-D1027

Dansylcadaverine Monodansyl cadaverine	Autophagy	Others
Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands.

HY-112803

GNE-371	DNA/RNA Synthesis	Cancer
GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like, with an IC₅₀ of 10 nM for TAF1(2).

HY-D1435

Oxonol VI	Na+/K+ ATPase	Neurological Disease
Oxonol VI acts as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is suitable for detecting changes of membrane potential associated with the activity of the (Na⁺ + K⁺)-ATPase in reconstituted vesicles.

HY-D1689

Rf470DL
Bacterial Infection

Rf470DL is a rotor-fluorogenic D-amino acid (RfDAA). Rf470DL can be used for labeling bacteria (Ex=470 nm, Em=640 nm).

HY-D1704

Bodipy TMR-X muscimol	GABA Receptor	Neurological Disease
Bodipy TMR-X muscimol is a Bodipy labeled Muscimol (HY-N2313) (Ex=543 nm, Em=572 nm). Muscimol is a GABAA agonist. Bodipy TMR-X muscimol can be used for imaging the spread of reversible brain inactivations.

HY-P1986

Z-DEVD-AFC	Caspase	Cancer
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity.

HY-138200

Cy5 maleimide Cyanine5 maleimide	DNA Stain Others	Others
Cy5 maleimide is a highly sensitive fluorescence dye, which can be used for labeling protein, antibody, nucleic acid molecule and so on.

HY-110251A

DFHBI-2T
DNA Stain Others Others

DFHBI-2T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=500 nm/523 nm). DFHBI-2T is used to image RNA in live cells.
HY-W013275

MCLA hydrochloride
Reactive Oxygen Species Others Others

MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.

HY-130768

N-(Azido-PEG3)-N-Fluorescein-PEG3-acid	PROTAC Linkers	Cancer
N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker which contains azide, fluorescein and carboxylic acid moieties.

HY-D1706

AMCA-6-dUTP
DNA Stain Others

AMCA-6-dUTP can be used for enzymatic labeling of DNA/cDNA.

HY-D0720

Lucigenin NSC-151912; L-6868	Reactive Oxygen Species	Others
Lucigenin(L-6868; NSC-151912) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.

HY-110251

DFHBI-1T	DNA Stain Others	Others
DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells.

HY-P1169

Ac-IETD-AFC
Caspase Others

Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B.

HY-D1676

Thymolphthalein monophosphate disodium hydrate	Phosphatase	Others
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum.

HY-D0226

Quinizarin 1,4-Dihydroxyanthraquinone	DNA/RNA Synthesis Fungal	Cancer Infection
Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (K_d=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth.

HY-D1543

Pyronin B	DNA Stain Others	Infection
Pyronin B is an organic cationic dye used for the staining of bacteria, mycobacteria and ribonucleic acids. Pyronin B is also used as a small hydrophobic (SH) protein channel inhibitor.

HY-P2270

Phalloidin-TRITC	Arp2/3 Complex	Others
Phalloidin-TRITC is a TRITC labeled, red fluorescence probe for F-actin. Phalloidin, bound to actin filaments, reacts covalently with amino acids Glu-llT, Met-ll9, and Met355, which are very close to the nucleotide binding site.

HY-D0162

Malachite green oxalate	IKK NF-κB Apoptosis	Cancer
Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green oxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green oxalate exhibits antitumor activity in vitro and in vivo.

HY-123051

Ac-WLA-AMC
Proteasome Inflammation/Immunology

Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate.

HY-B0883

Proflavine hemisulfate Proflavin hemisulfate; 3,6-Diaminoacridine hemisulfate	Bacterial Potassium Channel Autophagy	Infection
Proflavine hemisulfate, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent. Proflavine hemisulfate behaves as a pore blocker for K_ir3.2. Proflavine hemisulfate is a potential lead compound for K_ir3.2-associated neurological diseases.

HY-111263

NIAD-4	Amyloid-β	Neurological Disease
NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (K_i) of 10 nM.

HY-D1653

BDP 581/591 NHS ester	Reactive Oxygen Species Others	Others
BDP 581/591 NHS ester is a a borondipyrromethene dye (Ex=585 nm, Em=594 nm) that has relatively long fluorescence lifetime and two photon excitation cross section. BDP 581/591 NHS ester can be used for fluorescence polarization analysis and also reacts with reactive oxygen species (ROS) and alter fluorescence. BDP 581/591 NHS ester is also an NHS ester derivative that can be used to bind primary and secondary amine groups of proteins, peptides and other molecules.

HY-D1571

CellTracker Blue CMF2HC Dye	DNA Stain Others	Others
CellTracker Blue CMF2HC Dye is a blue dye, can be used in two-channel nuclei acid sequencing, with blue and purple excitation light (450-460 nm/400-405nm or 415-450 nm/480-525nm). CellTracker Blue CMF2HC Dye can be used to rapid determination of antibiotic sensitivity of microorganisms.

HY-114491

Rineterkib	ERK Raf	Cancer
Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF.

HY-D1684

DCDAPH	Amyloid-β	Neurological Disease
DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid (Aβ) plaques (λ_ex/λ_em=597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates (K_i=37 nM, K_d=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo.

HY-118159

Diphenyl-1-pyrenylphosphine DPPP	Reactive Oxygen Species Others	Others
Diphenyl-1-pyrenylphosphine (DPPP) is a fluoregenic peroxide reactive probe. Diphenyl-1-pyrenylphosphine exhibits a unique phototriggered aggregation-induced emission (AIE)/aggregation-induced quenching (ACQ) transition with a remarkable third-order nonlinear optical signal change.

HY-D0940

H2DCFDA DCFH-DA; 2',7'-Dichlorodihydrofluorescein diacetate	Reactive Oxygen Species	Others
H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm).

HY-111330

Hydroxyphenyl Fluorescein HPF	Reactive Oxygen Species	Others
Hydroxyphenyl fluorescein (HPF) is the reagent that can directly detect highly reactive oxygen species (hROS). Hydroxyphenyl fluorescein selectively and dose-dependently reacts with hROS, such as the hydroxyl radical and peroxynitrite, which exhibit strong fluorescence.

HY-P1004

Luciferase	Reactive Oxygen Species	Cancer
Luciferase from Vibrio fischeri has also been used in a study to investigate the sensitivity of dark mutants of various strains of luminescent bacteria to reactive oxygen species.

HY-18743

Coelenterazine	Reactive Oxygen Species	Cancer
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite.

HY-P3484

Dnp-PLGLWA-DArg-NH2 TFA	MMP	Cancer
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm).

HY-N2306

Aclacinomycin A Aclarubicin	Topoisomerase DNA/RNA Synthesis Proteasome Antibiotic	Cancer
Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis.

HY-D1705

Ac-ANW-AMC
Proteasome Inflammation/Immunology

Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm).
HY-116583

Resorufin butyrate
Cholinesterase (ChE) Metabolic Disease

Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm).
HY-D0027

7-Amino-4-methylcoumarin
Coumarin 120; AMC
Ser/Thr Protease Others

7-amino-4-methylcoumarin (Coumarin 120) has been used as a fluorogenic probe for many serine proteases.

HY-D0214

Rose Bengal sodium	Influenza Virus	Others
Rose Bengal sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities.

HY-122878

HS-131	HSP	Cancer
HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers.

HY-D0147

Resorufin pentyl ether Pentoxyresorufin	Bacterial	Infection
Resorufin pentyl ether (Pentoxyresorufin) is a Resazurin (HY-111391) analogue. Resorufin pentyl ether can function as a substrate probe to characterize and differentiate between a variety of inducers of cytochromes P-450. Resorufin pentyl ether has bactericidal activity against N. gonorrhoeae.

HY-P2536

Mca-Ala-Pro-Lys(Dnp)-OH	Angiotensin-converting Enzyme (ACE)	Others
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung.

Cat. No.	Product Name	Type

HY-D0367

Fluorescent Brightener 28
Fluorescent Dyes/Probes

Fluorescent Brightener 28 is a visible light emitting diode (LED)-light sensitive photoinitiator for free radical photopolymerizations.

HY-D1500

Fluorescent NIR 885	Fluorescent Dyes/Probes
Fluorescent NIR 885 is a cyanine near-infrared-absorbing dye. Fluorescent NIR 885 can be used as a photoprotective agent (extracted from patent WO2014006589 compound 1-35).

HY-D1496

Fluorescent Red Mega 485 NHS-ester
Fluorescent Dyes/Probes

Fluorescent Red Mega 485 NHS-ester is an amine conjugating fluorescent biolabel that can be used to label proteins.

HY-D1497

Fluorescent Red Mega 480	Fluorescent Dyes/Probes
Fluorescent Red Mega 480 is a dye that is specifically designed for multicolor techniques. Fluorescent Red Mega 480 is characterized by an extremely large stoke′s shift between excitation and emission maxima.

HY-136247

Cyanine 5 Tyramide Tyramide-Cy5	Fluorescent Dyes/Probes
Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.

HY-W040681

7-Dimethylaminocoumarin-4-acetic acid
Fluorescent Dyes/Probes

7-Dimethylaminocoumarin-4-acetic acid is a fluorescent probe.

HY-D1699

PFB-FDG	Fluorescent Dyes/Probes
PFB-FDG is a non-fluorescent galactosidase substrate that can be hydrolysed to green fluorescent PFB-F (Ex=485 nm, Em=535 nm). PFB-FDG can be used for the determination of β-galactosidase activity.

HY-137845

4-Methylumbelliferyl β-D-galactopyranoside	Fluorescent Dyes/Probes
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer.

HY-136248

Cyanine 3 Tyramide Tyramide-Cy3	Fluorescent Dyes/Probes
Cyanine 3 Tyramide (Tyramide-Cy3), an orange fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.

HY-126831

SBFI-AM
Fluorescent Dyes/Probes

SBFI-AM is a Na⁺ selective fluorescent indicator. SBFI-AM shows selectivity for Na⁺ over K⁺.

HY-D0023

Pyranine HPTS; Solvent Green 7	Fluorescent Dyes/Probes
Pyranine (HPTS; Solvent Green 7) is a pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu⁺ ion(λex=450 nm, λem=510 nm).

HY-126561

Green CMFDA CMFDA	Fluorescent Dyes/Probes
Green CMFDA (CMFDA) is a cell-permeable fluorescent probe that can be used a cell tracer. Green CMFDA can be cleaved by non-specific esterases common to living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope.

HY-P3474

Mca-PLGL-Dpa-AR-NH2
Fluorescent Dyes/Probes

Mca-PLGL-Dpa-AR-NH2 is a fluorescent peptide MMP substrate.
HY-D1628

Calcium Green BAPTA-2 AM
Fluorescent Dyes/Probes

Calcium Green BAPTA-2 AM is a fluorescent calcium indicator.
HY-151701

DiSulfo-Cy5 alkyne
Fluorescent Dyes/Probes

DiSulfo-Cy5 alkyne is a fluorescent dye can be used as a click chemistry reagent.

HY-D1570

BODIPY FL C12	Fluorescent Dyes/Probes
BODIPY FL C12 is a green fluorescent dye, fluorescent fatty acid dye. BODIPY FL C12 reacts with primary amines on biomolecules and can be used as a protein marker. BODIPY FL C12 can be used as a fluorescent probe that monitor fatty acyls.

HY-D1297

ER-Tracker Green
Fluorescent Dyes/Probes

ER-Tracker Green is a fluorescent dye that specific for endoplasmic reticulum.
HY-D1518

NerveGreen C1
Fluorescent Dyes/Probes

NerveGreen C1 is a fluorescent dye (Ex=500 nm, Em=615 nm).
HY-D1555

Cyanine7 DBCO
Cy7 DBCO
Fluorescent Dyes/Probes

Cyanine7 DBCO is a water-soluble NIR fluorescent dye with cycloalkyne moiety.
HY-129096

IDT307
Chromogenic Substrates

IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+).

HY-W088089

ICG-carboxylic acid	Fluorescent Dyes/Probes
ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue.

HY-D1695

LYCBX
Fluorescent Dyes/Probes

LYCBX is a neuronal tracer, a fluorescent biotin derivative of Lucifer Yellow.
HY-D0114

3-Carboxy-7-Hydroxycoumarin
Fluorescent Dyes/Probes

3-Carboxy-7-Hydroxycoumarin is a UV-light excitable fluorescent dye.
HY-D1572

Carbostyril 165
Fluorescent Dyes/Probes

Carbostyril 165 is an electronically neutral fluorescent dye (Ex: 351/364 nm, Em: >400 nm).

HY-D1698

PED6	Fluorescent Dyes/Probes
PED6 is a PLA₂ substrate fluorescent probe (EX/EM=488/530 nm) that is a BODIFY-labeled fluorescent phosphatidylethanolamine analogue. PED6 can be used for detection of phospholipase A₂.

HY-D1617

BODIPY 500/510 C1, C12	Fluorescent Dyes/Probes
BODIPY 500/510 C1, C12 is a fluorescent dye which is a fluorescent fatty acid analog. BODIPY 500/510 C1, C12 can be used as a fluorescent probe for fatty acid uptaken. BODIPY 500/510 C1, C12 can be used for the research of lipid transport.

HY-147889

BBR-BODIPY	Fluorescent Dyes/Probes
BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins.

HY-W099490

Bis[3,4,6-trichloro-2-(pentyloxycarbonyl)phenyl] oxalate	Fluorescent Dyes/Probes
Bis[3,4,6-trichloro-2-(pentyloxycarbonyl)phenyl] oxalate is a fluorescent dye that can be used for generation of chemiluminescence.

HY-D1696

MitoTracker Orange CMTMRos	Fluorescent Dyes/Probes
MitoTracker Orange CMTMRos is a fluorescent dye that labels mitochondria within live cells utilizing the mitochondrial membrane potential (Ex/Em: 551/576 nm).

HY-D1069

DBCO-Cy3 DBCO-Sulfo-Cy3	Fluorescent Dyes/Probes
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) *orange fluorescent* dye** with excitation maximum 555 nm and emission maximum of 580 nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations.

HY-D1436

PBFI
Fluorescent Dyes/Probes

PBFI is the fluorescent indicator that is widely used for the determination of intracellular concentrations of K⁺.
HY-D1151

HKOH-1
Fluorescent Dyes/Probes

HKOH-1 is a highly sensitive and selective fluorescent probe for detecting endogenous hydroxyl radicals.

HY-137100

Cy 5 hydrazide Cyanine5 hydrazide	Fluorescent Dyes/Probes
Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins.

HY-D1112

TFAX 546,SE triethylammonium	Fluorescent Dyes/Probes
TFAX 546,SE triethylammonium, an amine reactive yellow fluorescent dye, can forms bright and photostable conjugates with proteins and antibodies.

HY-W351339

BAPTA-TMFM
Fluorescent Dyes/Probes

BAPTA-TMFM is a fluorescent chelating indicator used to study the role of cytosolic free calcium.
HY-D1437

RH 237
Fluorescent Dyes/Probes

RH 237 is a voltage-sensitive fluorescent dye. RH 237 can be used for imaging neuron cells.
HY-D1550

10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515
Fluorescent Dyes/Probes

10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515 is a fluorescent dye for Cu²⁺ ion.

HY-D1537

Dibenzocyclooctyne-Cy5.5 DBCO-Cy5.5; Cyanine5.5 DBCO	Fluorescent Dyes/Probes
Dibenzocyclooctyne-Cy5.5 (DBCO-Cy5.5) is a fluorescent dye. Dibenzocyclooctyne-Cy5.5 can be used to syntheses calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging.

HY-135414B

Cyanine5 NHS ester iodide
Fluorescent Dyes/Probes

Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides.

HY-D0718

Nile Red Nile Blue A oxazone; Phenoxazone 9	Fluorescent Dyes/Probes
Nile Red (Nile Blue A oxazone) is a selective and hydrophobic fluorescent stain for intracellular lipid droplets and neutral lipids. Nile Red is intensely fluorescent in all organic solvents and the fluorescence colors range from golden yellow to deep red.

HY-141576

C6-NBD Sphinganine
Fluorescent Dyes/Probes

C6-NBD Sphinganine is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid.
HY-141575

C12-NBD-ceramide
Fluorescent Dyes/Probes

C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays.

HY-135239

Fura-FF pentapotassium	Fluorescent Dyes/Probes
Fura-FF pentapotassium is a low-affinity fluorescent dye for calcium (Ex/Em: 365/514 nm in the absence of calcium; 339/507 nm in the presence of a high calcium concentration).

HY-113870

6-NBDG	Fluorescent Dyes/Probes
6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques.

HY-D1614

BODIPY 493/503 methyl bromide
Fluorescent Dyes/Probes

BODIPY 493/503 methyl bromide, a green fluorescent dye, is a cell permeable and long-term staining agent (Ex=521 nm, Em=538 nm).
HY-D1269

Rhodamine-N3 chloride
Fluorescent Dyes/Probes

Rhodamine-N3 chloride is an azide-rhodamine fluorescent dye that can be used to label biomolecules containing alkyne groups.
HY-135414

Cyanine5 NHS ester chloride
Fluorescent Dyes/Probes

Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides.

HY-W020798

1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine	Fluorescent Dyes/Probes
1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine is a fluorescent probe with a polar phosphatidylethanolamine head group for the determination of surface lipid oxidation in lipoproteins and plasma.

HY-D0121

INDO 1	Fluorescent Dyes/Probes
INDO 1 is a fluorescent Ca²⁺ indicator, binds specifically to Ca²⁺ while emitting fluorescence, the maximum emission wavelength shifts from 485 nm before binding to 410 nm.

HY-D1485

3,3'-Diethylthiacyanine iodide	Fluorescent Dyes/Probes
3,3'-Diethylthiacyanine iodide is a cyanine fluorescent dye. 3,3'-Diethylthiacyanine iodide manifestes a pronounced affinity for bacterial cells.

HY-D0085

DiSC3(5)
Fluorescent Dyes/Probes

DiSC3(5) is a fluorescent probe often used as a tracer dye to assess the mitochondrial membrane potential.
HY-W269179

4-Bromomethyl-6,7-dimethoxycoumarin
Fluorescent Dyes/Probes

4-Bromomethyl-6,7-dimethoxycoumarin is a fluorescent label for carboxylic acids in chromatographic detection.

HY-D0121A

INDO 1 pentapotassium	Fluorescent Dyes/Probes
INDO 1 pentapotassium is a fluorescent Ca²⁺ indicator, binds specifically to Ca²⁺ while emitting fluorescence, the maximum emission wavelength shifts from 485 nm before binding to 410 nm.

HY-D1577

C6 NBD Lactosylceramide	Fluorescent Dyes/Probes
C6 NBD Lactosylceramide is a derivative of lactosylceramides, and can be used in lactosylceramide synthase assay as a fluorescent acceptor substrate. C6 NBD Lactosylceramide can also be used in cancer research.

HY-D1076

DiIC16(3)	Fluorescent Dyes/Probes
DiIC16(3) is the lipid-mimetic dialkylindocarbocyanine (DiI) derivative. DiIC16(3) is a lipophilic red-orange fluorescent. DiIC16(3) is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. DiIC16(3) preferentially enters late endosomes/lysosomes.

HY-D0075

DHPDS disodium salt	Fluorescent Dyes/Probes
DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver.

HY-W039519

7-Methoxycoumarin-3-carboxylic acid	Fluorescent Dyes/Probes
7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide.

HY-D1573

C6 NBD Phytoceramide
Fluorescent Dyes/Probes

C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS).

HY-D1593

BODIPY TMR-X alkyne	Fluorescent Dyes/Probes
BODIPY TMR-X alkyne, an orange-fluorescent dye, is an alkyne modified BODIPY TMR-X. BODIPY TMR-X alkyne can react with azides by the copper-catalyzed click reaction. BODIPY TMR-X alkyne is not sensitive to pH.

HY-D0068

DEAC, SE 7-Diethylaminocoumarin-3-carboxylic acid, SE	Fluorescent Dyes/Probes
DEAC, SE (7-Diethylaminocoumarin-3-carboxylic acid, SE) is an excellent blue fluorescent building block for labeling amine-containing biomolecules.

HY-W127707

Fluo-8 AM
Fluorescent Dyes/Probes

Fluo-8 AM is a calcium fluorescent probe that can be loaded into protoplasts to detect calcium in the flesh tissue cells of Malus domestica.

HY-D1526

N-(4-Anilino-1-naphthyl)maleimide	Fluorescent Dyes/Probes
N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λ_ex=355 nm, λ_em=448 nm.

HY-P2065

Ac-VEID-AMC
Fluorescent Dyes/Probes

Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm).

HY-D0036

Br-Mmc 4-Bromomethyl-7-methoxycoumarin	Fluorescent Dyes/Probes
Br-Mmc (4-Bromomethyl-7-methoxycoumarin) is often used as fluorescent label for the determination of compounds possessing a carboxylic group. Br-Mmc is used for the determination fatty acids by TLC or HPLC.

HY-P3791

N-Succinyl-Ile-Ile-Trp-AMC
Fluorescent Dyes/Probes

N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY).
HY-D1041

ICG-OSu
ICG NHS ester
Fluorescent Dyes/Probes

ICG-OSu (ICG NHS ester), a near-infrared fluorescent agent, is amine-reactive and has been widely used to design in vivo imaging probes.
HY-W040143

2',7'-Dichlorofluorescein
Fluorescent Dyes/Probes

2',7'-Dichlorofluorescein acts as a fluorescent probe (Ex=496 nm and Em=525 nm) for reactive oxygen species (ROS) measurement.

HY-D0110A

Fura-2 pentapotassium	Fluorescent Dyes/Probes
Fura-2 pentapotassium is a scaled fluorescent dye that can be used for intracellular calcium imaging with the K_d value of 140 nM. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca²⁺ level.

HY-D1533

RhoNox-1	Fluorescent Dyes/Probes
RhoNox-1 is a fluorescent dye. RhoNox-1 shows a high selection of Fe(II) ions that can be used as fluorescent probes for specific label labile ferrous iron [Fe(II)]. RhoNox-1 can be used to identify the level of the intracellular labile iron pool.

HY-D1451

PKH 26	Fluorescent Dyes/Probes
PKH 26 is a lipophilic membrane dye and widely used to determine cell proliferation in heterogeneous cells by flow cytometry. It is a red‐fluorescent dye (Ex/Em=551/567nm).

HY-43520

BODIPY-FL	Fluorescent Dyes/Probes
BODIPY-FL is a potent fluorescent dye. BODIPY-FL can be used to label probe or primer for fluorescent quenching-based quantitative detection of specific DNA/RNA.BODIPY-FL-labeled monoterpenoid can be used to examine the features of a broad spectrum of Gram-positive and Gram-negative bacteria and pathogenic fungi as well.

HY-D1594

BODIPY TR Cadaverine	Fluorescent Dyes/Probes
BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A.

HY-D1608

BODIPY FL Thapsigargin	Fluorescent Dyes/Probes
BODIPY FL Thapsigargin is a potent green fluorescent dye. BODIPY FL Thapsigargin inhibits intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum. BODIPY FL Thapsigargin used for investigation of thapsigargin binding sites in live cells.

HY-W351340

4-(Benzyloxy)-2-nitrophenol
Fluorescent Dyes/Probes

4-(Benzyloxy)-2-nitrophenol is a synthetic building block that can be used in the synthesis of fluorescent ion indicators.
HY-D1055

MitoSOX Red
Fluorescent Dyes/Probes

MitoSOX red, a fluorescent dye, specifically targets mitochondrial ROS. MitoSOX red can be used to observed the distribution of mitochondrial ROS.

HY-130015

HKSOX-1 (5/6-mixture)	Fluorescent Dyes/Probes
HKSOX-1 is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 exhibits excellent selectivity and sensitivity towards superoxide anion radical.

HY-D1428

Di-4-ANEPPDHQ
Fluorescent Dyes/Probes

Di-4-ANEPPDHQ, a fluorescent probe for the visualisation of membrane microdomains in living Arabidopsis thaliana cells.

HY-151753

Trisulfo-Cy5.5-Alkyne	Fluorescent Dyes/Probes
Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.

HY-110211

BODIPY TMR-X SE	Protein Labeling
BODIPY TMR-X SE is a potent fluorescent dye. BODIPY TMR-X SE can be used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, orange fluorescent light. (λ_ex=544 nm, λ_em=570 nm).

HY-103373

PE154	Fluorescent Dyes/Probes
PE154 (Compound 13) is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC₅₀s=280 pM and 16 nM, respectively). PE154 can label β-amyloid plaques in histochemical analysis.

HY-110212

BODIPY TR-X BODIPY TR-X NHS Ester	Protein Labeling
BODIPY TR-X (BODIPY TR-X NHS Ester) is a potent fluorescent dye. BODIPY TR-X can be used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, red fluorescent light. (λ_ex=545 nm, λ_em=560 nm).

HY-D1266

RB-OPD NO-red	Fluorescent Dyes/Probes
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm).

HY-D1678

5(6)-Carboxynaphthofluorescein diacetate	Fluorescent Dyes/Probes
5(6)-Carboxynaphthofluorescein diacetate is a fluorescent substrate for esterase assays that can be cleaved by intracellular esterases, producing red fluorescence to measure enzyme activity (Ex = 590 nm; Em = 645 nm).

HY-124197

Coumarin hydrazine
Fluorescent Dyes/Probes

Coumarin hydrazine is a fluorescent chemical probe (λ_ex=420–450/λ_em=468 nm) to label cellular protein- and lipid-bound carbonyls.

HY-D0159

ZnAF-1F	Fluorescent Dyes/Probes
ZnAF-1F is a potent fluorophore for with an K_d value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn²⁺ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm.

HY-137296

Lumogallion	Fluorescent Dyes/Probes
Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm.

HY-W012642A

2-Aminopurine dihydrochloride	Fluorescent Dyes/Probes
2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence.

HY-D1299

meso-CF3-BODIPY 2 CF3-substituted Tetramethyl BODIPY	Fluorescent Dyes/Probes
meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λ_abs) of 553 nm and emission wavelength (λ_em) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy.

HY-W411215

1,4-Diacetoxy-2,3-dicyanobenzene	Fluorescent Dyes/Probes
1,4-Diacetoxy-2,3-dicyanobenzene is a cell-permeable fluorescent probe. 1,4-Diacetoxy-2,3-dicyanobenzene crosses the cell membrane and is cleaved by cytosolic esterases to the fluorescent pH indicator 2,3-dicyano-hydroquinone (DCH). 1,4-Diacetoxy-2,3-dicyanobenzene can be used to monitor intracellular pH.

HY-D1391

PbS/CdS QDs
PbS/CdSe QD
Quantum Dots

PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window.

HY-W074143

Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride	Fluorescent Dyes/Probes
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride is an oxygen-sensitive fluorescent indicator widely used as a probe for luminescence detection and quantitative oxygen determination.

HY-D0122

6-Iodoacetamidofluorescein	Fluorescent Dyes/Probes
6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins.

HY-101887

Calcein Blue	Fluorescent Dyes/Probes
Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator.

HY-D1068

Cy5-DBCO DBCO-Sulfo-Cy5	Fluorescent Dyes/Probes
Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR) *red fluorescent* dye** with λ_abs and λ_em of  646 nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background.

HY-D1265

EtS-DMAB HClO-green	Fluorescent Dyes/Probes
EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells.

HY-D1319

Cyanine5 carboxylic acid chloride Cy5 acid chloride	Fluorescent Dyes/Probes
Cyanine5 carboxylic acid chloride (Cy5 acid chloride) is a fluorescent dye containing a non-activated carboxylic acid (Ex=646 nm, Em=662 nm). Cyanine5 carboxylic acid chloride is an non-reactive dye that can be used in control samples.

HY-131498

MOCAc-PLGL(Dpa)AR	Fluorescent Dyes/Probes
MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2) and MMP-7. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues.

HY-D1517

FM 2-10	Fluorescent Dyes/Probes
FM 2-10 is a fluorescent dye. FM 2-10 is a less hydrophobic version of FM 1-43 (HY-D1434). FM 2-10 can be used for identifying actively firing neurons and investigating the mechanisms of activity-dependent vesicle cycling.

HY-D1595

BODIPY FL Cholesterol	Fluorescent Dyes/Probes
BODIPY FL Cholesterol is a green fluorescent, lipophilic probe. BODIPY FL Cholesterol can be used for the research of lipid transport processes and lipid-protein interactions.

HY-D1257

Msr-Ratio Msr-green	Fluorescent Dyes/Probes
Msr-Ratio (Msr-green) is a ratiometric fluorescent probe of methionine sulfoxide reductase (λex=375 nm, λem=550 nm). Msr-Ratio is used for monitoring the enzyme activity in vitro and in live cells.

HY-130022

HKPerox-1	Fluorescent Dyes/Probes
HKPerox-1 is a yellow-emitting fluorescent probe with excellent selectivity and sensitivity toward H₂O₂. HKPerox-1 can be used for molecular imaging of endogenous H₂O₂ in living cells.

HY-W277900

2-Methoxy-2,4-diphenylfuran-3-one	Fluorescent Dyes/Probes
2-Methoxy-2,4-diphenylfuran-3-one is a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and MMP-9 by zymography.

HY-D1527

N-(3-Fluoranthenyl)maleimide	Fluorescent Dyes/Probes
N-(3-Fluoranthyl)maleimide is a thiol fluorescent probe with a lifetime of 20 nsec. N-(3-Fluoranthyl)maleimide has a maximum excitation wavelength of 370 nm and can be used to study the time-dependent processes of biopolymers.

HY-130017

HKSOX-1r (5/6-mixture)	Fluorescent Dyes/Probes
HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical.

HY-D1532

DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS	Fluorescent Dyes/Probes
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite.

HY-136957

Fluorescein-6-isothiocyanate	Fluorescent Dyes/Probes
Fluorescein-6-isothiocyanate is a fluorescent isomeric haptenic probes with K_ds of 8.74, 2.72 and 1.88 for N-Acetyl-L-Lysine, normal mouse IgG and 4-4-20, respectively.

HY-D1254

Trx-red NBL-SS perchlorate	Fluorescent Dyes/Probes
Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm).

HY-D1565

Cy7.5 maleimide
Fluorescent Dyes/Probes

Cy7.5 maleimide is a near infrared fluorescent (NIRF) dye that can be used in labeling protein sulfhydryl (-SH) groups and in vivo imaging.

HY-15938

5-FAM SE	Fluorescent Dyes/Probes
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates.

HY-D1067

NIR dye-1	Fluorescent Dyes/Probes
NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group.

HY-D1656

BDP 581/591 carboxylic acid	Fluorescent Dyes/Probes
BDP 581/591 carboxylic acid is a fluorescent dye (Ex=585 nm, Em=594 nm). BDP 581/591 carboxylic acid has a free carboxylic acid group, which can be catalyzed by a catalyst (such as EDC or HATU) to react with primary amines to form stable amide bonds. BDP 581/591 carboxylic acid is highly photostable and can be used for ROS detection.

HY-D0968B

Cy 3 (Non-Sulfonated) (triethylamine)

Cyanine3 triethylamine

Fluorescent Dyes/Probes

Cy 3 Non-Sulfonated (Cyanine3) triethylamine is a cyanine (Cy) dye, and a fluorescent label with green channel for protein and nucleic acid. Cy 3 Non-Sulfonated triethylamine is a fluorescent photoproduct of Cyanine5 via photoconversion upon photoexcitation. Cy 3 Non-Sulfonated triethylamine can be used to high-density single-particle tracking in a living cell without using UV illumination and cell-toxic additives (Ex=470 nm; Em=515 nm and 565 nm nm).

HY-W089353

8-Phenyl-BODIPY 505/515	Fluorescent Dyes/Probes
8-Phenyl-BODIPY 505/515, a phenyl-substituted BODIPY derivative, is a fluorophore, 8-Phenyl-BODIPY 505/515 can be used as fluorescent probe.

HY-D1237

BODIPY 505/515	Fluorescent Dyes/Probes
BODIPY 505/515, a lipophilic bright green fluorescent dye was tested for lipid detection in the microalga Tetraselmis subcordiformis. BODIPY 505/515 displays excitation/emission maxima of 505/515 nm, respectively, and has been used for live and fixed cell applications.

HY-D1106

Py-BODIPY-NHS ester	Fluorescent Dyes/Probes
Py-BODIPY-NHS ester is a cell-permeable and fluorescent energy transfer probe. Py-BODIPY-NHS ester tracer yields strong cellular engagement and proves to be optimal for MET kinase. The live-cell energy transfer technique can perform a broad-coverage, quantitative analysis of intracellular kinase target engagement.

HY-151775

BDP TR azide	Fluorescent Dyes/Probes
BDP TR azide is a click chemistry reagent containing an azide group that can react with alkynes, DBCO and BCN. BDP TR azide is also a fluorescent dye that can be used in fluorescence polarization assays and microscopy.

HY-131029

Janelia Fluor® 646, Maleimide JF646, Maleimide	Fluorescent Dyes/Probes
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-W040209

2-(Naphthalen-1-yl)-5-phenyloxazole α-NPO	Fluorescent Dyes/Probes
2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye. 2-(Naphthalen-1-yl)-5-phenyloxazole has a nitrogen atom in its structure that can interfere with the nitrogen content from the amination step.

HY-D1460

Fluorescein Di-β-D-Glucuronide

Fluorescent Dyes/Probes

Fluorescein Di-β-D-Glucuronide, a fluorescent probe, can be utilized to non-invasively image the intestinal bacterial β-glucuronidase activity in nude mice. Fluorescein Di-β-D-Glucuronide-based imaging reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, which would facilitate pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies.

HY-D1256

Msr-blue	Fluorescent Dyes/Probes
Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm).

HY-W345102

4-Methylumbelliferyl β-cellotrioside
Chromogenic Substrates

4-Methylumbelliferyl β-cellotrioside, a chromogenic substrate for β-glycosidases, is a cellulose fluorescent derivative.

HY-151801

DIBA-Cy5

Fluorescent Dyes/Probes

DIBA-Cy5 is a fluorescent DIBA antagonist made up be DIBA-alkyne binding Cyanine5 fluorophores (Cy5) and polyethylene glycol (PEG) biomolecules. DIBA-Cy5 can serve as a fluorescent ligand, suitable for probe attachment through click chemistry. DIBA-Cy5 exerts a high binding affinity to type-2 mAChR (M2R) with the K_d value of 1.80 nM, can directly stain M2R receptors in the sinoatrial node of a mouse heart.

HY-D1506

Fl-DIBO	Dyes
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference.

HY-145385

Coelenteramide	Fluorescent Dyes/Probes
Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca²⁺, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent.

HY-129811

Bis-ANS dipotassium	Fluorescent Dyes/Probes
Bis-ANS dipotassium is a fluorescent probe of hydrophobic protein. Bis-ANS binds to tubulin with a K_d of 2 μM. Bis-ANS dipotassium is a potent biphasic modulator of protein liquid-liquid phase separation (LLPS). Bis-ANS dipotassium promotes LLPS at low concentrations but suppresses LLPS at high concentrations.

HY-D1574

C6 NBD Sphingomyelin	Fluorescent Dyes/Probes
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane.

HY-D1324

Cyanine5.5 hydrazide dichloride	Fluorescent Dyes/Probes
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λ_ex=684 nm, λ_em=710 nm).

HY-D1378

C-Laurdan	Fluorescent Dyes/Probes
C-Laurdan is a fluorescent probe for imaging lipid rafts with environmentally sensitive fluorescence. C-Laurdan exhibits strong photostability under two-photon excitation and can be used for single and two-photon fluorescence imaging to detect lipid membrane properties such as membrane lateral organisation, various membrane-associated processes, etc.

HY-135009

2-Di-1-ASP	Fluorescent Dyes/Probes
2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA.

HY-151776

Cy3 methyltetrazine TZ-Cy3	Fluorescent Dyes/Probes
Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a *tetrazine-modified fluorescent* probe** that can be used to analyze protein phosphorylation in solution and living cells.

HY-131028

Janelia Fluor® 646 TFA JF646 TFA	Fluorescent Dyes/Probes
Janelia Fluor® 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1459

BODIPY 665/676
Fluorescent Dyes/Probes

BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation.

HY-D1327

Cyanine3 azide chloride	Fluorescent Dyes/Probes
Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λ_ex=684 nm, λ_em=710 nm)^[1].

HY-D1515

FM1-84 Neurodye GH1-84	Fluorescent Dyes/Probes
FM1-84 (Neurodye GH1-84) is a fluorescent dye. FM1-84 has lipophilic and facilitates association with membranes, resulting in an increase in fluorescence intensity (λ_ex=510 nm, λ_em=625 nm). FM1-84 can be used for synaptic vesicle recycling in neurons research.

HY-W011618

N-(9-Acridinyl)maleimide	Fluorescent Dyes/Probes
N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione.

HY-D0133

NBD-X acid	Fluorescent Dyes/Probes
NBD-X acid is a fluorescent probe for the study of fatty acids and sterols. NBD-X acid provides better yields for labelling biopolymers compared to NBD chloride and fluoride. The fluorescence spectrum of the NBD derivative is highly sensitive to the environment and the fluorescence intensity is significantly reduced in aqueous solutions.

HY-151757

Trisulfo-Cy5-Alkyne	Fluorescent Dyes/Probes
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye.

HY-D1602

BODIPY FL-DHPE	Fluorescent Dyes/Probes
BODIPY FL DHPE is a green-fluorescent phospholipid probe. BODIPY FL DHPE labels lipid 1,2-dihexadecanoyl-sn-glycero-phosphoethanolamine (DHPE), labeled liposomes can be internalized by membrane fusion. BODIPY FL DHPE can be used for investigations of membrane surface and membrane fusion. (λ_ex=505 nm, λ_em=511 nm).

HY-D1372

Cyanine3 amine hydrochloride	Fluorescent Dyes/Probes
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λ_ex=555 nm, λ_em=570 nm).

HY-D1432

FITC-C6-DEVD-FMK	Fluorescent Dyes/Probes
FITC-C6-DEVD-FMK, a fluorescently labeled caspase-3 inhibitor, can be used for detection of active caspase-3 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-3 in living cells. Z-DEVD-FMK is a specific caspase-3 inhibitor.

HY-D1433

FITC-C6-LEHD-FMK	Fluorescent Dyes/Probes
FITC-C6-LEHD-FMK, a fluorescently labeled caspase-9 inhibitor, can be used for detection of active caspase-9 in mammalian cells undergoing apoptosis. FITC-C6-DEVD-FMK provides a convenient means for sensitive detection of activated caspase-9 in living cells. Z-LEHD-FMK is a specific caspase-9 inhibitor.

HY-D1690

sBADA	Fluorescent Dyes/Probes
sBADA is a potent green fluorescent dye. sBADA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA is used to label peptidoglycans in bacterial cell walls in situ. (λ_ex=490 nm, λ_em=510 nm).

HY-D1092

DiBAC4(5)	Fluorescent Dyes/Probes
DiBaC4(5) is a fluorescent voltage-sensitive dye that can be used to monitor the transmembrane potentials when Papain-dissociated retinal cells from adult zebrafish were exposed to GABAergic ligands. DiBaC4(5) is a potential-sensitive fluorescence dye.

HY-151544

PNE-Lyso	Fluorescent Dyes/Probes
PNE-Lyso is a activatable fluorescent probe. PNE-Lyso can be used to detect intracellular pH and hexosaminidases with two kinds of fluorescence signals. PNE-Lyso can be used to distinguish apoptosis from necrosis through visualizing lysosome morphology. PNE-Lyso is capable of investigating the drug-induced cell death process.

HY-103466

FM4-64	Fluorescent Dyes/Probes
FM4-64, a membrane-selective red fluorescent dye, belongs to the FM family of styrylpyridinium dyes. FM4-64 is widely used to study endocytosis and exocytosis, vesicle trafficking and organelle organization in living animal.

HY-114352

BODIPY FL-X	Fluorescent Dyes/Probes
BODIPY FL-X is a green-fluorescent dye. BODIPY FL-X has the succinimidyl ester covalently coupled to proteins. BODIPY FL-X has high fluorescence quantum yield and is relatively insensitive to pH change. (λ_ex=504 nm, λ_em=510 nm).

HY-D0115

7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester	Fluorescent Dyes/Probes
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids.

HY-D1607

BODIPY FL SSE	Protein Labeling
BODIPY FL SSE is a potent fluorescent dye. BODIPY FL SSE is used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY FL SSE can reactive with primary amines on biomolecules to emit green fluorescence. (λ_ex=502 nm, λ_em=511 nm).

HY-114353

BDP FL azide	Fluorescent Dyes/Probes
BDP FL azide is a BDP dye connector containing an azide group capable of Click Chemistry. The green fluorophore is representative of the borodipyrromethane class of fluorescent dyes and has a high quantum yield in aqueous environments, high stability to photobleaching and is compatible with FAM fluorescence measurement instruments.

HY-D1603

BODIPY FL-EDA	Fluorescent Dyes/Probes
BODIPY FL-EDA is a fluorescent dye. BODIPY FL-EDA is an aliphatic-amine analog, and it can be coupled with aldehydes and ketones. BODIPY FL-EDA can be used for the detection of modified and normal deoxynucleotides and to determine DNA damage and genomic DNA methylation.

HY-D1596

Cyanine 3.5 chloride Cy3.5 NHS ester chloride; Cy 3.5 chloride	Fluorescent Dyes/Probes
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm).

HY-137042

Cyanine5 alkyne Alkyne-Cy5	Fluorescent Dyes/Probes
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC).

HY-118155

9-Amino-6-chloro-2-methoxyacridine	Fluorescent Dyes/Probes
9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H⁺/solute antiport system.

HY-D0165

Naphthoresorcinol 1,3-Dihydroxynaphthalene	Fluorescent Dyes/Probes
Naphthoresorcinol (1,3-Dihydroxynaphthalene) is a fluorescent dye (λ_ex=330 nm, λ_em=380 nm) that can react with the NPPD (a tracer) and concentrated HCl and develop a red color. Naphthoresorcinol could be used as a background electrolyte (BGE) to determine the carbohydrates.

HY-131027

Janelia Fluor® 646, Azide JF646, Azide	Fluorescent Dyes/Probes
Janelia Fluor® 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor® 646, Azide can be used for live-cell imaging experiments. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-130027

HKOCl-4 BXY2142	Fluorescent Dyes/Probes
HKOCl-4 (BXY2142) is a rhodol-based *yellow fluorescent* probe for the detection of hypochlorous acid** with excellent sensitivity and selectivity. HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. E_x: 530 nm; E_m 557 nm.

HY-N6716

Filipin complex

Fluorescent Dyes/Probes

Filipin complex is a potent broad spectrum 28-membered ring pentaene macrolide antifungal antibiotic. Filipin complex is also a highly fluorescent polyene. Filipin complex specifically binds free cholesterol and is well established as a histochemical marker for the detection of unesterified cellular cholesterol. Filipin complex consists of four analogues (Filipins I-IV), with Filipin III (HY-N6718) comprising the bulk (>70%) of the complex.

HY-114351

BODIPY FL hydrazide	Fluorescent Dyes/Probes
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λ_ex=495 nm, λ_em=516 nm).

HY-148073

MeO-Succ-Arg-Pro-Tyr-AMC	Chromogenic Substrates
MeO-Succ-Arg-Pro-Tyr-AMC is an analogue of 7-amido-4-methylcoumarin (HY-D0027). MeO-Succ-Arg-Pro-Tyr-AMC is a sensitive fluorescent substrate chymotrypsin-like protease. (λ_ex=341 nm, λ_em=441 nm).

HY-D0969

3,3'-Dioctadecyloxacarbocyanine perchlorate DiO; DiOC18(3)	Fluorescent Dyes/Probes
3,3′-Dioctadecyloxacarbocyanine perchlorate is a green fluorescent lipophilic tracer, which is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes.

HY-D1394

AgAuSe QDs AgAuSe	Quantum Dots
AgAuSe QDs (AgAuSe) is a near infrared (NIR) fluorescent quantum dots (QDs), with a bright emission from 820 to 1170 nm. AgAuSe QDs can be used for the research in biomedical imaging and NIR devices.

HY-D1581

BODIPY 505/515-8-C3-COOH	Fluorescent Dyes/Probes
BODIPY 505/515-8-C3-COOH is a green fluorescing derivative, as a fluorescent dye for imaging lipid droplets in nannochloropsis. BODIPY 505/515-8-C3-COOH can be used for the research of flow cytometric high-throughput screening and cell sorting.

HY-118562

Dansylamide
Fluorescent Dyes/Probes

Dansyl amide is a fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group.
HY-D1508

2-(Pyren-1-ylaminocarbonyl)ethyl methanethiosulfonate
Fluorescent Dyes/Probes

2-(Pyren-1-ylaminocarbonyl)ethyl methanethiosulfonate is a fluorescent.

HY-D1074

DiOC3(3) 3,3'-Dipropyloxacarbocyanine iodide	Fluorescent Dyes/Probes
DiOC3(3) (3,3'-Dipropyloxacarbocyanine iodide) is a green fluorescent lipophilic dye with cell membrane permeability. DiOC3(3) can be used to stain cell membranes and other lipid-soluble biological structures.

HY-D1274A

Sulfo-cyanine3 azide sodium	Fluorescent Dyes/Probes
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents.

HY-D0163

Methyl Green	DNA Stain
Methyl Green is a potent fluorescent dye. Methyl Green is a DNA stains of cells and electrophoretic gels. Methyl Green can be used as a stain for direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm.

HY-D0950A

Methyl Green zinc chloride	DNA Stain
Methyl Green zinc chloride is a potent fluorescent dye. Methyl Green zinc chloride is a DNA stains of cells and electrophoretic gels. Methyl Green zinc chloride can be used as direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm.

HY-D1065

NIR-H2O2	Fluorescent Dyes/Probes
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H₂O₂ with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H₂O₂ in living cells and mice.

HY-D1320

Cyanine5 azide chloride	Dyes
Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λ_ex=646 nm, λ_em=662 nm).

HY-D1321

Cyanine5 amine hydrochloride Lumiprobe Cy 5 amine	Dyes
Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λ_ex=646 nm, λ_em=662 nm).

HY-141511

Coppersensor 1

Fluorescent Dyes/Probes

Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu⁺ with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu⁺) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases.

HY-U00440

FHZ
Fluorescent Dyes/Probes

FHZ is a fluorescent probe.

HY-D1539

Cyanine 5.5 azide CY 5.5 azide; Lumiprobe CY 5.5 azide	DNA Stain
Cyanine 5.5 azide (CY 5.5 azide) is a potent fluorescent dye. Cyanine 5.5 azide can label DNA. Cyanine 5.5 azide can be used for NIR live organism imaging. (λ_ex=684 nm, λ_em=710 nm).

HY-130533

ReAsH-EDT2	Protein Labeling
ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λ_ex=530 nm, λ_em=592 nm).

HY-D1591

BODIPY R6G methyl ester

Fluorescent Dyes/Probes

BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic therapy, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis.

HY-D1599

Rhodamine 6G hydrazide R6GH	Fluorescent Dyes/Probes
Rhodamine 6G hydrazide (R6GH) is a fluorescent dye. Rhodamine 6G hydrazide can be used in selective colorimetric and fluorescent sensing.

HY-133821

N-Methylmesoporphyrin IX

Fluorescent Dyes/Probes

N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies.

HY-D1556

DOPE-CF	Fluorescent Dyes/Probes
DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids.

HY-D1503

Glut-Phe-AMC
Fluorescent Dyes/Probes

Glut-Phe-AMC is a fluorescent dye.
HY-116215

2-NBDG
Fluorescent Dyes/Probes

2-NBDG, a fluorescent D-glucose analog, is a fluorescent indicator for monitoring glucose uptake into living cells. Ex: 467 nm; Em 542 nm.

HY-120993

1,N6-Ethenoadenosine 5'-monophosphate sodium

1,N6-Etheno-AMP sodium; 1,N6-ε-AMP sodium

Fluorescent Dyes/Probes

1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm.

HY-N7131

Coumarin 6	Fluorescent Dyes/Probes
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems.

HY-W321446

Dansyl ethylenediamine	Fluorescent Dyes/Probes
Dansyl ethylenediamine is a fluorescent probe. Dansyl ethylenediamine can be used for synthesis of protein-imprinted polymers which is capable of specific transduction of protein binding events into fluorescent signal change.

HY-D1445

LysoSensor PDMPO	Fluorescent Dyes/Probes
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes (Abs=329 nm; Em=440 nm).

HY-D0104

Fluorescein-O-acetate
Fluorescent Dyes/Probes

Fluorescein-O-acetate is a fluorescent reagent.
HY-101876

Rhodamine 800
Fluorescent Dyes/Probes

Rhodamine 800 is a near-infrared fluorescent dye.

HY-110250

DFHBI	Fluorescent Dyes/Probes
DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells.

HY-D1176

Calcium Green 1AM	Fluorescent Dyes/Probes
Calcium Green 1AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Calcium Green 1AM is converted to the fluorescent calcium indicator by intracellular esterases.

HY-D1513

O-Methyl-O-(N-butylfluorescein)phosphate
Fluorescent Dyes/Probes

O-Methyl-O-(N-butylfluorescein)phosphate is a fluorescent dye.
HY-110210

BODIPY-FL NHS ester
BODIPY FL,SE
Fluorescent Dyes/Probes

BODIPY-FL NHS ester is a bright, green fluorescent dye.
HY-D1548

1-(Azidomethyl)pyrene
Fluorescent Dyes/Probes

1-(Azidomethyl)pyrene is a fluorescent dye.
HY-D1029

Biotin-11-dUTP
Fluorescent Dyes/Probes

Biotin-11-dUTP is a fluorescent substitute for dTTP.
HY-100512

Benzenepentacarboxylic Acid
Pentacarboxybenzene
Fluorescent Dyes/Probes

Benzenepentacarboxylic acid (BA), a novel fluorescent probeas to detect and scavenge HO-.
HY-D1512

Oxonol 595
Fluorescent Dyes/Probes

Oxonol 595 is a voltage-sensitive fluorescent dye.

HY-D0083

DiI DiIC18(3)	Fluorescent Dyes/Probes
DiI (DiIC18(3)) is a lipophilic carbocyanine fluorescent dye for membrane labeling. DiI has an absorption maximum at 549 nm and an emission maximum 565 nm. DiI is mildly fluorescent in aqueous suspension, but becomes bright when bound to cell membrane.

HY-D0074

Prodan	Fluorescent Dyes/Probes
Prodan, a solvatochromic fluorophore, has been used as a microenvironment-sensitive membrane reporter. Based on the chemistry of Prodan, fluorescent nucleosides are designed and synthesized.The fluorescent nucleosides sensitively varied the Stokes shift values depending on the orientational polarizability of the solvent.

HY-118540

Resazurin

Diazoresorcinol

Fluorescent Dyes/Probes

Resazurin (Diazoresorcinol) is a water-soluble, non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal).

HY-135636

Ponatinib Acid
Fluorescent Dyes/Probes

Ponatinib Acid, an analogue of Ponatinib, is usually used as a labeled chemical or fluorescent probe.
HY-D1029A

Biotin-11-dUTP trisodium
Fluorescent Dyes/Probes

Biotin-11-dUTP trisodium is a fluorescent substitute for dTTP.
HY-D1514

NIR-641 N-succinimidyl ester
Fluorescent Dyes/Probes

NIR-641 N-succinimidyl ester is a fluorescent dye.
HY-135638

Imatinib Acid
Fluorescent Dyes/Probes

Imatinib Acid, an analogue of Imatinib, is usually used as a labeled chemical or fluorescent probe.
HY-135637

Nilotinib Acid
Fluorescent Dyes/Probes

Nilotinib Acid, an analogue of Nilotinib, is usually used as a labeled chemical or fluorescent probe.
HY-D0815

Propidium Iodide
PI
Fluorescent Dyes/Probes

Propidium Iodide is a red-fluorescent dye that can be used to stain cells.
HY-D0972

Thioflavine S
Thioflavin S; Direct Yellow 7
Fluorescent Dyes/Probes

Thioflavine S is a fluorescent histochemical marker of dense core senile plaques.

HY-D0251

Fluorescein Uranine	Fluorescent Dyes/Probes
Fluorescein (Uranine) is widely used as a fluorescent tracer in medicinal and biological applications and tumor infected tissues tracer. Fluorescein (Uranine) is a representative green fluorophore that has been widely used as a scaffold of practically useful green fluorescent probes.

HY-100041

Bromobimane
Monobromobimane
Fluorescent Dyes/Probes

Bromobimane is essentially nonfluorescent and converts into fluorescent products when reacts with small thiols.
HY-135639

Alkyne-probe 1
Fluorescent Dyes/Probes

Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe.
HY-135640

TAMRA-probe 1
Fluorescent Dyes/Probes

TAMRA-probe 1 is a commonly used fluorescent probe for labeling.
HY-101937B

L-ANAP hydrochloride
Fluorescent Dyes/Probes

L-ANAP hydrochloride is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa).
HY-D1519

Naphthalene-1,2-dicarbaldehyde
Fluorescent Dyes/Probes

Naphthalene-1,2-dicarbaldehyde is a fluorescent dye.
HY-101888

Cresyl Violet acetate
Fluorescent Dyes/Probes

Cresyl Violet acetate is a red fluorescent stain, which can be used to stain neurons.
HY-101937

L-ANAP
Fluorescent Dyes/Probes

L-ANAP is a genetically encodable and polarity-sensitive fluorescent unnatural amino acid (Uaa).
HY-D0041

Calcein-AM
Calcein acetoxymethyl ester
Fluorescent Dyes/Probes

Calcein-AM is cell-permeable fluorescent dye used to determine the cell viability.

HY-101878

Texas Red Sulforhodamine 101; SR101	Fluorescent Dyes/Probes
Texas Red (Sulforhodamine 101) is an amphoteric rhodamine *red fluorescent* dye** (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as a cell type-selective fluorescent marker of astrocytes both in vivo and in slice preparations.

HY-D1528

MTSEA-Fluorescein
Fluorescent Dyes/Probes

MTSEA-Fluorescein is a fluorescent probe that can be used for ion channel research.

HY-100575

Acriflavine Acriflavinium chloride 3,6-Acridinediamine mix	Fluorescent Dyes/Probes
Acriflavine is a fluorescent dye for labeling high molecular weight RNA. It is also a topical antiseptic.

HY-W019823

4-MUNANA
Fluorescent Dyes/Probes

4-MUNANA is a fluorescent substrate used for neuraminidase activity assay.
HY-101937A

(±)-ANAP
Fluorescent Dyes/Probes

(±)-ANAP is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
HY-101937C

(±)-ANAP hydrochloride
Fluorescent Dyes/Probes

(±)-ANAP hydrochloride is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
HY-101889

Cresyl Violet perchlorate
Oxazine 9 perchlorate
Fluorescent Dyes/Probes

Cresyl Violet perchlorate is a red fluorescent stain, which can be used to stain neurons.
HY-D1473

2-(2-Benzoxazolyl)phenyl benzoate
Fluorescent Dyes/Probes

2-(2-Benzoxazolyl)phenyl benzoate is a photoactivated fluorescent dye.

HY-D0785

NBD-F 4-Fluoro-7-nitrobenzofurazan	Fluorescent Dyes/Probes
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent which is developed for amino acid analysis. NBD-F reacts with primary or secondary amines to produce a fluorescent product and used for analysis of amino acids and low molecular weight amines.

HY-D1401

OG 488, acid
Fluorescent Dyes/Probes

OG 488, acid, a fluorescent pH indicator, has many applications in biochemistry and neurosciences.
HY-D0982

Zinquin
Fluorescent Dyes/Probes

Zinquin is a fluorescent sensor and used to observe reactive Zn²⁺. λex\em = 364/385 nm.
HY-D0035

MPAC-Br
Fluorescent Dyes/Probes

MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC.
HY-D1531

4-Methyl-2-phenylchromenylium tetrafluoroborate
Fluorescent Dyes/Probes

4-Methyl-2-phenylchromenylium tetrafluoroborate is a fluorescent dye.
HY-101883

BCECF-AM
Fluorescent Dyes/Probes

BCECF-AM is a cell membrane permeable compound widely used as a fluorescent indicator for intracellular pH.
HY-D0986

TMA-DPH
Fluorescent Dyes/Probes

TMA-DPH is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm).
HY-D0076

4,5-Diaminofluorescein
DAF-2
Fluorescent Dyes/Probes

4,5-Diaminofluorescein is a fluorescent detector for nitric oxide (NO) in cells and tissues.

HY-Y0016

Rhodamine B Basic Violet 10; Brilliant Pink B; Rhodamine O; Tetraethylrhodamine	Fluorescent Dyes/Probes
Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and drugs.

HY-D0993

Acridine Orange 10-Nonyl Bromide
Nonylacridine orange
Fluorescent Dyes/Probes

Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λ_ex: 489 nm, λ_em: 525 nm).
HY-D0989

Rhod-2 AM
Fluorescent Dyes/Probes

Rhod-2 AM is a fluorescent, mitochondrial probe (λ_ex=552 nm, λ_em=581 nm).
HY-147171

2,7-Bis(alloxycarbonylamino)-9-chloroacridine
Fluorescent Dyes/Probes

2,7-Bis(alloxycarbonylamino)-9-chloroacridine can be used as a fluorescent label.

HY-101879

Acridine Orange hydrochloride	Fluorescent Dyes/Probes
Acridine Orange hydrochloride is a cell-permeable fluorescent dye that binds to nucleic acids, resulting in an altered spectral emission.

HY-W127843

Mag-Indo-1 tetrapotassium salt
Fluorescent Dyes/Probes

Mag-Indo-1 tetrapotassium salt is a cell impermeable fluorescent probe for Mg²⁺ detection.
HY-D1489

Ethyl eosin
Fluorescent Dyes/Probes

Ethyl eosin is a fluorescent dye with an absorption peak at 527 nm and an absorption shoulder at 487 nm.

HY-120959

DAUDA	Fluorescent Dyes/Probes
DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1].

HY-D1623

Cyanine3 carboxylic acid chloride	Fluorescent Dyes/Probes
Cyanine3 carboxylic acid chloride is a non-toxic red fluorescent dye with good solubility in organic solvents. Cyanine3 carboxylic acid chloride can be used as a non-reactive fluorophore for experimental control and calibration. Cyanine3 carboxylic acid chloride can also be synthesized with targeted drugs as fluorescent probes for rapid detection of drug reactions.

HY-123533

Resorufin
NSC 12097
Fluorescent Dyes/Probes

Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte.

HY-123533A

Resorufin sodium salt NSC 12097 sodium salt	Fluorescent Dyes/Probes
Resorufin sodium salt (NSC 12097 sodium salt) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte.

HY-W013967

1,6-Diphenylhexa-1,3,5-triene
Fluorescent Dyes/Probes

1,6-Diphenylhexa-1,3,5-triene is a fluorescent probe.
HY-D1502

FURA-PE3/AM
Fluorescent Dyes/Probes

FURA-PE3/AM is a leak-resistant fluorescent calcium indicator dye.
HY-D1048

DiR
Cy7 DiC18
Fluorescent Dyes/Probes

DiR (Cy7 DiC18) is a lipophilic, near-infrared fluorescent cyanine dye used for staining membranes.
HY-D1586

Cyanine5 Boc-hydrazide chloride
Fluorescent Dyes/Probes

Cyanine5 Boc-hydrazide (chloride) is a cyanine5-labeled and Boc-protected hydrazide fluorescent dye.
HY-D0984

TMRM
Fluorescent Dyes/Probes

TMRM is a cell-permeant cationic lipophilic red fluorescent dye (λ_ex=530 nm, λ_em=592 nm).
HY-D1524

N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid
Fluorescent Dyes/Probes

N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid is a fluorescent reagent.
HY-D1483

3,3-Dibutylthiacarbocyanine iodide
Fluorescent Dyes/Probes

3,3-Dibutylthiacarbocyanine iodide is a fluorescent dye with an excitation of 559 nm and an emission 604 nm.
HY-D1470

BADAN
Fluorescent Dyes/Probes

BADAN (6-Bromoacetyl-2-dimethylaminonaphthalene) is a polarity-sensitive fluorescent probe.
HY-101892

DiBAC4(3)
Fluorescent Dyes/Probes

DiBAC4(3) is a voltage-sensitive fluorescent dye (λ_ex=490 nm, λ_em=505 nm).
HY-D0078

DCIA
Fluorescent Dyes/Probes

DCIA is a fluorescent dye. DCIA contains a coumarin fluorophore and conjugates specifically with free cysteines in the protein.
HY-D1471

10-(3-Sulfopropyl)acridinium Betaine
Fluorescent Dyes/Probes

10-(3-Sulfopropyl)acridinium Betaine is a fluorescent dye with high durability (>3 months).
HY-W216621

Pinacyanol iodide
Fluorescent Dyes/Probes

Pinacyanol iodide is a fluorescent cyanine dye. Pinacyanol iodide exhibits ultrafast excited state isomerization.

HY-137896

4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium	Fluorescent Dyes/Probes
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium is a fluorescent dye. 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium can be used to demonstrate retrograde axonal transport to label secondary antibodies and as a fluorescent whole cell stain.

HY-D1482

Sulfo-Cy5-tetrazine	Fluorescent Dyes/Probes
Cy5 Tetrazine is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Its absorption and emission spactra are almost identical to those of Alexa Fluor 647, CF 647 Dye, or any other Cyanine5 based fluorescent dyes.

HY-110393

CLR1501
Fluorescent Dyes/Probes

CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound.
HY-D1423

Dibromobimane
Fluorescent Dyes/Probes

Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides.
HY-126172

9-Anthryldiazomethane
Fluorescent Dyes/Probes

9-Anthryldiazomethane is a fluorescent labeling reagent, which can be used for detecting fatty acids and derivatives.
HY-D0789

ANTS
Fluorescent Dyes/Probes

ANTS is a fluorescent dye. ANTS and DPX are encapsulated in liposomes can be an effective approach for measuring membrane leakage.

HY-D1044

Rhodamine 101 chloride Rhodamine 640 (chloride)	Fluorescent Dyes/Probes
Rhodamine 101 chloride (Rhodamine 640 chloride) is a bright fluorescent dye with excitation and emission maxima of 565 and 595 nm, respectively.

HY-D0081A

5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin
Fluorescent Dyes/Probes

5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin is a fluorescent indicator for NO.
HY-101897

Fura-2 AM
Fura-2 Acetoxymethyl ester
Fluorescent Dyes/Probes

Fura-2 AM is a high affinity, intracellular, UV light-excitable and ratiometric fluorescent Ca²⁺ indicator.
HY-D0135

12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid
Fluorescent Dyes/Probes

12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid is an amine-reactive fluorescent dye.

HY-111391

Resazurin sodium Diazoresorcinol sodium	Fluorescent Dyes/Probes
Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.

HY-135634

GNF-2-PEG-acid
Fluorescent Dyes/Probes

GNF-2-PEG-acid, an analogue of GNF-2, is usually used as a labeled chemical or fluorescent probe.
HY-101898

Indo-1 AM
Indo-1 Acetoxymethyl ester
Fluorescent Dyes/Probes

Indo-1 AM is a fluorescent Ca²⁺ indicator (λ_ex=340 nm, λ_em=405/485 nm).
HY-D0984A

TMRM Perchlorate
T668
Fluorescent Dyes/Probes

TMRM Perchlorate is a cell-permeant cationic lipophilic red fluorescent dye (λ_ex=530 nm, λ_em=592 nm).
HY-D1564

Cy7.5 hydrazide
Fluorescent Dyes/Probes

Cy7.5 hydrazide is a fluorophore Cy7.5-labeled hydrazide fluorescent dye.
HY-W271064

1-Methylpyrene
Fluorescent Dyes/Probes

1-Methylpyrene is a fluorescent probe and is also a carcinogen in rodents (λ_ex = 346 nm; λ_em = 378 nm).
HY-D0149

4-(Trifluoromethyl)umbelliferone
Fluorescent Dyes/Probes

4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes.
HY-101894

Dihydrorhodamine 123
DHR 123
Fluorescent Dyes/Probes

Dihydrorhodamine 123 (DHR 123) is a fluorescent probe (λ_ex=488 nm, λ_em=525 nm).
HY-D1089

6-JOE, SE
Fluorescent Dyes/Probes

6-JOE, SE is an amine-reactive fluorescent probe and is suitable for postsynthetic labeling of amino-modified oligonucleotides.
HY-D0816

Rhodamine 123
RH-123; R-22420
Fluorescent Dyes/Probes

Rhodamine 123 (RH-123; R-22420) is a fluorescent dye (λ_ex=503 nm, λ_em=527 nm).
HY-135835

6-FAM-PEG3-Azide
Fluorescent Dyes/Probes

6-FAM-PEG3-Azide is a fluorescent dye that can be used to label oligonucleotide.
HY-D1522

N,N'-Bis[2-(acetamido)ethyl]-N,N'-dimethyl rhodamine
Fluorescent Dyes/Probes

N,N'-Bis[2-(acetamido)ethyl]-N,N'-dimethyl rhodamine is a fluorescent reagent.

HY-D1387

Naloxone fluorescein acetate	Fluorescent Dyes/Probes
Naloxone fluorescein acetate is the fluorescent-derivative of Naloxone. Naloxone is an opioid antagonist. Naloxone is the antidote for reversing the effects of an opioid overdose.

HY-D0715

Fluorescamine
Ro 20-7234
Protein Labeling

Fluorescamine( Ro 20-7234) is a spiro compound that is not fluorescent itself, but reacts with primary amines to form highly fluorescent products.

HY-D0098

Fluorescein-5-maleimide N-(5-Fluoresceinyl)maleimide	Fluorescent Dyes/Probes
Fluorescein-5-maleimide is a fluorescent thiol-reactive dye used to conjugate fluorescein to proteins (excitation: 494 nm, emission: 519 nm).

HY-D0021

Ethidium bromide EtBr; Homidium bromide	Fluorescent Dyes/Probes
Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

HY-U00451

ATP-Red 1	Fluorescent Dyes/Probes
ATP-Red 1 is a multisite-binding switchable fluorescent probe, and can selectively and rapidly responds to intracellular concentrations of ATP in living cells.

HY-D0090

MQAE	Fluorescent Dyes/Probes
MQAE is a fluorescent indicator that is quenched via collision with chloride, and is more sensitive and selective than ³⁶Cl and microelectrode-based methods for chloride measurement in cells.

HY-15943

6-TAMRA 6-Carboxytetramethylrhodamine	Fluorescent Dyes/Probes
6-TAMRA has been a widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry.

HY-D0069

CPM
Fluorescent Dyes/Probes

CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye. The excitation/emission maxima is 384/470 nm.
HY-108715

Real Thiol
Fluorescent Dyes/Probes

Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
HY-D0091

7-Ethoxy-4-trifluoromethylcoumarin
Fluorescent Dyes/Probes

7-Ethoxy-4-trifluoromethylcoumarin is a fluorescent substrate of various enzymes of the cytochrome P450 superfamily
HY-101899

Monochlorobimane
Chlorobimane
Fluorescent Dyes/Probes

Monochlorobimane (Chlorobimane) is a fluorescent dye (λ_ex=380 nm, λ_em=470 nm) to measure glutathione (GSH) in cellular assays.
HY-D1085

AMCA-X SE
Fluorescent Dyes/Probes

AMCA-X SE is a fluorescent molecules compounded for the tagging of biomolecules with a maximum absorption of 354 nm and a maximum emission of 442 nm.
HY-D1613

BODIPY FL C5-HPC
Fluorescent Dyes/Probes

BODIPY FL C5-HPC is a lipophilic green fluorescent dye (Ex/Em: 500/510 nm).
HY-D1051

Cy3-N3
Fluorescent Dyes/Probes

Cy3-N3 is a Cy3-azide fluorescent dye used to label for protein and nucleic acid.
HY-D1469

5-Carboxyrhodamine 6G succinimidyl ester
R6G-SE
Fluorescent Dyes/Probes

5-Carboxyrhodamine 6G succinimidyl ester (R6G-SE) is an amine reactive fluorescent dye.
HY-D1158

HKOCl-4m
Fluorescent Dyes/Probes

HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl).
HY-D1109

5(6)-SFX ,SE
Fluorescent Dyes/Probes

5(6)-SFX ,SE (Compound SFX-SE) is a fluorescent dye for labeling primary amines and nascent proteins.

HY-D0786

3-Morpholinobenzanthrone	Fluorescent Dyes/Probes
3-Morpholinobenzanthrone is a fluorescent membrane probe, possessing higher dipole moment values in the excited-state than in the ground-state.

HY-D0814

DAPI dihydrochloride 4',6-Diamidino-2-phenylindole dihydrochloride	Fluorescent Dyes/Probes
DAPI dihydrochloride (4',6-diamidino-2-phenylindole) is a fluorescent stain by binding in the minor grove of A-T rich sequences of DNA.

HY-130025

HKOCl-3
Fluorescent Dyes/Probes

HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid. E_x: 490 nm; E_m 527 nm.

HY-D0099

Fluorescein-5-thiosemicarbazide	Fluorescent Dyes/Probes
Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives.

HY-D1086

6-Carboxy-X-rhodamine, succinimidyl ester 6-ROX, SE	Fluorescent Dyes/Probes
6-Carboxy-X-rhodamine, succinimidyl ester (6-ROX, SE) is a fluorescent dye for oligonucleotide labeling and automated DNA sequencing.

HY-139579

Pafolacianine
OTL 38
Fluorescent Dyes/Probes

Pafolacianine (OTL 38) is a fluorescent marker made of near-infrared dye used in detecting ovarian cancer lesions during surgical procedures.
HY-D1458

Peroxyfluor 1
Fluorescent Dyes/Probes

Peroxyfluor 1 is a cell-permeable probe for H₂O₂. Peroxyfluor 1 represents a first-generation, green-fluorescent probe.
HY-D0933

Auramine O
Fluorescent Dyes/Probes

Auramine O is a yellow fluorescent dye and can be used to stain acid-fast bacteria. Auramine O is toxic and resistant in the environment.
HY-135635

ABL-001-Amide-PEG3-acid
Fluorescent Dyes/Probes

ABL-001-Amide-PEG3-acid, an analogue of ABL-001, is usually used as a labeled chemical or fluorescent probe.
HY-D1612

BODIPY Fl C5-Ceramide
Fluorescent Dyes/Probes

BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye, which can visualise individual cells.

HY-101859

NucPE1 Nuclear Peroxy Emerald 1	Fluorescent Dyes/Probes
NucPE1 (Nuclear Peroxy Emerald 1) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.

HY-124171

Zinquin ethyl ester	Fluorescent Dyes/Probes
Zinquin ethyl ester is a zinc ion-specific fluorophore. Zinquin ethyl ester is a lipophilic, zinc-sensitive, fluorescent derivative of Zinquin that is able to penetrate cell membranes.

HY-D1611

BODIPY FL-C5 NHS Ester	Fluorescent Dyes/Probes
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers.

HY-D1159

HKOH-1r
Fluorescent Dyes/Probes

HKOH-1r is a highly sensitive and selective fluorescent probe which is used for detecting endogenous hydroxyl radicals in living cells.

HY-D1598

Sulfo-CY3 tetrazine potassium	Fluorescent Dyes/Probes
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates.

HY-15937

5(6)-FAM SE 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester; 5(6)-Carboxyfluorescein succinimidyl ester mixed isomers	Fluorescent Dyes/Probes
5(6)-FAM SE is an amine-reactive green fluorescent dye widely used for labeling proteins or other molecules that contain a primary or secondary aliphatic amine.

HY-102055

JAK2 JH2 Tracer
Fluorescent Dyes/Probes

JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a K_d of value 0.2 μM.

HY-D1255

Sel-green	Fluorescent Dyes/Probes
Sel-green, a selective selenol fluorescent probe, is applied to quantify the Sec content in the selenoenzyme thioredoxin reductase and image endogenous Sec in live HepG2 cells.

HY-112498

Cy3 NHS ester Cyanine3 NHS ester	Fluorescent Dyes/Probes
Cy3 NHS ester (Cyanine3 NHS ester) is a yellow emitting fluorescent dye for labeling amino-groups in biomolecules. Used to label soluble proteins, peptides, and oligonucleotides/DNA.

HY-D1516

NerveGreen C3	Fluorescent Dyes/Probes
NerveGreen C3 is a cationic styrene based fluorescent dye. NerveGreen C3 can be used to track synaptic activity at neuromuscular junctions or synapses.

HY-D0040

Calcein Fluorexon	Fluorescent Dyes/Probes
Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium.

HY-D0981

7-Amino-4-(trifluoromethyl)coumarin Coumarin 151; AFC	Fluorescent Dyes/Probes
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.

HY-D1644

Bella Fluor 350 Phalloidin	Fluorescent Dyes/Probes
Bella Fluor 350 Phalloidin is a blue-fluorescent dye. Bella Fluor 350 Phalloidin shows a high affinity for F-actin and can be used for cytoskeletal protein imaging.

HY-101882

BCECF 2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein	Fluorescent Dyes/Probes
BCECF is a pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0–8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.

HY-D1580

C12 NBD Lactosylceramide	Fluorescent Dyes/Probes
C12 NBD Lactosylceramide is a derivative of Lactosylceramide labeled with a C12 NBD fluorescent group. C12 NBD Lactosylceramide can be used to identify Lactosylceramides.

HY-D1475

SIR-6-COOH
Fluorescent Dyes/Probes

SIR-6-COOH is a fluorescent dye. SIR-6-COOH can be used for staining proteins in live-cell STED imaging
HY-D1535

IR 813 perchlorate
Fluorescent Dyes/Probes

IR 813 perchlorate is a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm) and can be used for visualizing regional lymph nodes in mice.

HY-136277

DFHO	Fluorescent Dyes/Probes
DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a K_d value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells.

HY-D1494

FSB	Fluorescent Dyes/Probes
FSB is a fluorescent dye that can be used to detect filamentous tau and to label human amyloid lesions with high sensitivity and specificity (excitation: 390 nm, emission: 520 nm).

HY-D0830

Calcein tetraethyl ester Fluorexon tetraethyl ester	Fluorescent Dyes/Probes
Calcein tetraethyl ester is a fluorescent dye, is used in biology as it can be transported through the cellular membrane into live cells, which makes it useful for testing of cell viability and for short-term labeling of cells.

HY-D1558

1,3,5,7-Tetramethyl-2,6-diiodo-C3-SE-BODIPYs
Fluorescent Dyes/Probes

1,3,5,7-Tetramethyl-2,6-diiodo-C3-SE-BODIPYs is a fluorescent dye, and a BODIPY derivative.

HY-125623

MitoPerOx	Fluorescent Dyes/Probes
MitoPerOx is a fluorescent ratio-probe of lipid peroxidation. MitoPerOx can be taken up very rapidly into mitochondria within cells, thereby responding to changes in mitochondrial lipid peroxidation.

HY-D1440

Rhodamine B, tetramethyl-, isothiocyanate	Fluorescent Dyes/Probes
Rhodamine B, tetramethyl-, isothiocyanate (Tetramethylrhodamine B isothiocyante) is a fluorescent dye. Rhodamine B, tetramethyl-, isothiocyanate has a strong two-photon absorption at about 830 nm.

HY-D1606

BODIPY FL prazosin	Fluorescent Dyes/Probes
BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with K_i values of 14.5, 43.3 nM for α1a-AR and α1b-AR, respectively. BODIPY FL prazosin also is a fluorescent ligand with the excitation and emission wavelengths are 485 and 535 nm, respectively. BODIPY FL prazosin can be used for study the differences in the subcellular localization of α1-adrenoceptor subtypes.

HY-D0127

Merocyanin 540	Fluorescent Dyes/Probes
Merocyanin 540 is a fluorescent membrane probe that selectively stains the membranes of a wide variety of electrically excitable cells, but not those of nonexcitable cells (Ex/Em: 540/580 nm).

HY-103684

RT-NH2 Real Thiol-NH2	Fluorescent Dyes/Probes
RT-NH2 is a RealThiol prototype without the carboxylic acid groups. RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus, which is a hallmark of protein binding for fluorescent probe.

HY-D1638

Biocytin Lucifer Yellow potassium	Fluorescent Dyes/Probes
Biocytin Lucifer Yellow potassium is a water soluble fluorescent dye. Biocytin Lucifer Yellow potassium exhibits strong fluorescence from 450 to 650 nm, and can be used for tracing retinal neurons.

HY-145746

Sulfo-Cy5 azide
Fluorescent Dyes/Probes

Sulfo-Cy5 azide is a fluorescent dye and nontargeted contrast agent. Sulfo-Cy5 azide has been used to label and image RNA.
HY-D1457

DND-189
Fluorescent Dyes/Probes

DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles.

HY-D0080

Laurdan	Fluorescent Dyes/Probes
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase.

HY-D0140

Chromoionophore I ETH 5294	Fluorescent Dyes/Probes
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble.

HY-D1683

NBD-PE	Fluorescent Dyes/Probes
NBD-PE is an effective *lipid fluorescent* probe** (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology.

HY-D0048

5-TAMRA-SE 5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester	Fluorescent Dyes/Probes
5-TAMRA-SE is an amine-reactive fluorescent agent, its conjugates yield bright, pH-insensitive orange-red fluorescence (approximate excitation/emission maxima ~546/579) with good photostability.

HY-W247131

DASPEI	Fluorescent Dyes/Probes
DASPEI is a fluorescent dye. DASPEI is a styryl dye that stains mitochondria of live cells. DASPEI has a large fluorescence Stokes shift and is taken up relatively slowly as a function of membrane potential.

HY-D1488

Ethyl benzo[6,7]-4-oxo-4H-quinolizine-3-carboxlate
Fluorescent Dyes/Probes

Ethyl benzo[6,7]-4-oxo-4H-quinolizine-3-carboxlate (Compound 3) is a Mg²⁺ selective fluorescent indicator.

HY-128536

KMG-104AM	Fluorescent Dyes/Probes
KMG-104AM, a selective fluorescein-derived magnesium fluorescent membrane-permeable probe, successfully incorporates into PC12 cells and is used to Intracellular 3D Mg²⁺ Imaging .

HY-D1529

4-Methylumbelliferyl phosphate (2-amino-2-methyl-1,3-propanediol)	Fluorescent Dyes/Probes
4-Methylumbelliferyl phosphate (2-amino-2-methyl-1,3-propanediol) is a fluorescent substrate, can be used as substrate buffer of enzyme assay.

HY-D1498

Mag-Fluo-4 AM
Fluorescent Dyes/Probes

Mag-Fluo-4 AM is a fluorescent dye. Mag-Fluo-4 AM can be used to measure changes in free [Ca²⁺] within the endoplasmic reticulum (ER).

HY-B1422

9-Aminoacridine Aminacrine	Fluorescent Dyes/Probes
9-Aminoacridine (Aminacrine) is a highly fluorescent dye used as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator. 9-Aminoacridine is an effective antibacterial agent with caries-disclosing features.

HY-144603

Neuropeptide Y Y1 receptor antagonist 1	Fluorescent Dyes/Probes
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, is a potent antagonist of neuropeptide Y Y¹ receptor (Y¹R), with a K_i of 0.19 nM.

HY-D1493

FIM-1	Fluorescent Dyes/Probes
FIM-1 is a fluorescent PKC (protein kinase C) probe that can be used for mitochondrial staining. FIM-1 inhibits PKC and acts as ATP-competitive catalytic site inhibitor.

HY-15944

5(6)-TAMRA 5(6)-Carboxytetramethylrhodamine	Fluorescent Dyes/Probes
5(6)-TAMRA contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm.

HY-135056

MitoTracker Green FM	Fluorescent Dyes/Probes
MitoTracker Green FM is a green-fluorescent dye that can selectively accumulate in the mitochondrial matrix. MitoTracker Green FM covalently binds to mitochondrial proteins by reacting with free thiol groups of cysteine residues.

HY-D1592

BODIPY TMR C5-maleimide	Fluorescent Dyes/Probes
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides.

HY-W027544

MCA	Fluorescent Dyes/Probes
MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities.

HY-D1028

DiD perchlorate	Fluorescent Dyes/Probes
DiD perchlorate is a far-red fluorescent lipophilic cyanine dye. DiD perchlorate can rapidly and stably integrate into the phospholipid cell membrane. DiD perchlorate is used to cells tracking.

HY-137928

H-Ala-4MβNA hydrochloride
Fluorescent Dyes/Probes

H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M.
HY-P3475

Mca-VDQMDGW-K(Dnp)-NH2
Fluorescent Dyes/Probes

Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity.

HY-D1094

Carboxy-SNARF 1 (5/6-mixture) SNARF 1	Fluorescent Dyes/Probes
Carboxy-SNARF 1 (5/6-mixture) (SNARF 1) is a fluorescent probe that is sensitive to pH. Carboxy-SNARF 1 (5/6-mixture) can be used for measurement of intracellular pH.

HY-D0722

5(6)-CFDA 5-(6)-Carboxyfluorescein diacetate; CFDA	Fluorescent Dyes/Probes
5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) is a cell-permeant, amine-reactive green fluorescent probe used to stain cells for analysis in applications. (λ_ex: 492 nm; λ_em: 517 nm).

HY-133705

Geldanamycin-FITC	Fluorescent Dyes/Probes
Geldanamycin-FITC, a Geldanamycin fluorescent probe, can be used in a fluorescence polarization assay for HSP90 inhibitors. Geldanamycin-FITC also can be used for detection of cell surface HSP90.

HY-121030

DACM N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide	Fluorescent Dyes/Probes
DACM (N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide) is a thiol-directed fluorescent dye (Ex=396 nm, Em=468 nm).

HY-110213

BODIPY 630/650X	Fluorescent Dyes/Probes
BODIPY 630/650X is a fluorescent conjugate of the adenosine receptor ligand N-ethylcarboxamido-adenosine (NECA). BODIPY 630/650X displays excitation/emission maxima of 630/650 nm, respectively.

HY-103470

K114	Fluorescent Dyes/Probes
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC₅₀ of 20-30 nM. K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).

HY-D0924

Cy5.5 Sulfo-Cyanine5.5	Fluorescent Dyes/Probes
Cy5.5 (Sulfo-Cyanine5.5) is a near-infrared fluorescent dye (Ex=673 nm, Em=707 nm) used to label biological molecules, such as peptides, proteins, and oligonucleotides.

HY-151708

CalFluor 488 Azide	Fluorescent Dyes/Probes
CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes.

HY-D1161

True Blue NCI 240899	Fluorescent Dyes/Probes
True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival.

HY-15559A

Hoechst 33342 trihydrochloride
bisBenzimide H 33342 trihydrochloride; HOE 33342 trihydrochloride
DNA Stain

Hoechst 33342 trihydrochloride is a membrane permeant blue fluorescent DNA stain.
HY-P1003

Ac-DEVD-AMC
Chromogenic Substrates

Ac-DEVD-AMC is the Caspase-3 fluorescent substrate.

HY-D1642

Bella Fluor 594 Phalloidin	Fluorescent Dyes/Probes
Bella Fluor 594 Phalloidin is a photostable red-fluorescent probe with a high affinity for F-actin (Excitation/Emission=581/609 nm). Bella Fluor 594 Phalloidin can be used in cytoskeletal protein imaging.

HY-D1579

C12 NBD Globotriaosylceramide	Fluorescent Dyes/Probes
C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside.

HY-128692

Lucifer Yellow CH dilithium salt	Fluorescent Dyes/Probes
Lucifer Yellow CH dilithium salt is a highly fluorescent dye that is useful in marking nerve cells. Lucifer Yellow CH dilithium salt is assumed to be nontoxic, and it is membrane impermeable and highly dissociated at physiological pH values.

HY-D0079

Dihydroethidium Hydroethidine; PD-MY 003	Fluorescent Dyes/Probes
Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red (Ex/Em=518/616 nm).

HY-D1523

Z-Arg-Arg-4MβNA triacetate	Fluorescent Dyes/Probes
Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λ_ex = 355 nm, λ_em = 430 nm).

HY-66022

5-FAM 5-Carboxyfluorescein	Fluorescent Dyes/Probes
5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm.

HY-126793

2′,7′-Dichlorofluorescein diacetate DCFH2-DA	Fluorescent Dyes/Probes
2′,7′-Dichlorofluorescein diacetate (DCFH-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon.

HY-D1093

Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture)	Fluorescent Dyes/Probes
Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe that is sensitive to pH. Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) can be used for measurement of intracellular pH.

HY-D1691

BODIPY-581/591 NHS ester	Fluorescent Dyes/Probes
BODIPY-581/591 NHS ester is a bright, red fluorescent dye (excitation: 581 nm; emission: 591 nm). BODIPY-581/591 NHS ester shows unique hydrophobic properties for staining lipids, membranes, and other lipophilic compounds.

HY-125746

BODIPY-Cholesterol	Fluorescent Dyes/Probes
BODIPY-cholesterol is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 480/508 nm).

HY-D1249

Calcein (mixture of isomers)	Fluorescent Dyes/Probes
Calcein mixture of isomers is a calcium-dependent fluorescent molecule. Calcein mixture of isomers can be used to study bone metabolism (in vivo) and to stain depressed areas (in vitro). Calcein mixture of isomers can also be used for fluorometry and EDTA titration of calcium.

HY-D0097

7-Fluorobenzofurazan-4-sulfonic acid ammonium	Fluorescent Dyes/Probes
7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label. 7-Fluorobenzofurazan-4-sulfonic acid ammonium can be used for detecting dissolved thiol-disulfide (e.g., Cys, GSH).

HY-15560

Hoechst 34580
HOE 34580
DNA Stain

Hoechst 34580 is a cell-permeable fluorescent dye for staining DNA and nuclei.
HY-15621A

DMA trihydrochloride
DNA Stain

DMA trihydrochloride is a fluorescent compound (λ_ex=340 nm, λ_em=478 nm).

HY-D1630

4-Di-10-ASP	Fluorescent Dyes/Probes
4-Di-10-ASP is a fluorescent lipophilic tracer (Excitation 485 nm; Emission 620 nm). 4-Di-10-ASP can be used to stain phospholipid membranes in a specific manner.

HY-W090090

BODIPY 493/503 Pyrromethene 546; BDP 493/503 lipid stain	Fluorescent Dyes/Probes
BODIPY 493/503 (Pyrromethene 546) is a fluorescent neutral lipid dye (Ex/Em: 493/503 nm). BODIPY 493/503 can facilitate quantification of neutral lipid content by flow cytometry and observation of lipid droplets (LDs) by microscopy.

HY-D0060

4-Di-2-ASP	Fluorescent Dyes/Probes
4-Di-2-ASP, a styryl pyridinium fluorescent dye, is a vital mitochondrial marker. 4-Di-2-ASP shows reliable and specific labelling of pulmonary NEBs (neuroepithelial bodies).

HY-D1022A

Biotin-16-dUTP trisodium Biotin-16-deoxyuridine-5'-triphosphate trisodium	Fluorescent Dyes/Probes
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications.

HY-D1022

Biotin-16-dUTP Biotin-16-deoxyuridine-5'-triphosphate	Fluorescent Dyes/Probes
Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications.

HY-D0721

6-CFDA 6-Carboxyfluorescein diacetate	Fluorescent Dyes/Probes
6-CFDA (6-Carboxyfluorescein diacetate) is a fluorescent probe that can be used in flow cytometry and fluorescence microscopy. 6-CFDA also can be applied in intravital multiphoton microscopy to research hepatobiliary metabolism in animals.

HY-D1111

TFAX 568, SE	Fluorescent Dyes/Probes
TFAX 568, SE is an orange fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 568, SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG).

HY-D1648

8-(2,4,6-Trimethylphenyl)-BODIPY	Fluorescent Dyes/Probes
8-(2,4,6-Trimethylphenyl)-BODIPY is a highly fluorescent dye, can be used as photosensitizer or synthesize other BODIPY-based photosensitizer (λ_abs=502 nm, λ_em^max=516 nm).^{(*abs: main absorption maxima)}

HY-15562

HOE 32021
DNA Stain

Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.
HY-15563

HOE 33187
DNA Stain

Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.

HY-15558A

Hoechst 33258 trihydrochloride bisBenzimide H 33258 trihydrochloride; H 33258 trihydrochloride	DNA Stain
Hoechst 33258 trihydrochloride is a fluorescent dyes, which can be used as a cell dye for DNA.

HY-15560B

Hoechst 34580 tetrahydrochloride
HOE 34580 tetrahydrochloride
DNA Stain

Hoechst 34580 tetrahydrochloride is a cell-permeable fluorescent dye for staining DNA and nuclei.
HY-15622

meta-iodoHoechst 33258
DNA Stain

Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.
HY-D0968

Cy 3 Non-Sulfonated
Cyanine3
Protein Labeling

Cy 3 Non-Sulfonated (Cyanine3) is a fluorescent label for protein and nucleic acid.
HY-15558

Hoechst 33258
bisBenzimide H 33258; H 33258
DNA Stain

Hoechst 33258 is a fluorescent dye that emits blue fluorescence when bound to dsDNA.

HY-D1264

PMQA Zn-green	Fluorescent Dyes/Probes
PMQA (Zn-green), an 8-aminoquinoline-based ratiometric fluorescent sensor, demonstrates the Zn²⁺-induced redshift of emission (85 nm). PMQA (Zn-green) is a cell membrane-permeable probe and suitable for imaging Zn²⁺ in living cells.

HY-D1605

BODIPY FL L-Cystine	Fluorescent Dyes/Probes
BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λ_ex=504 nm, λ_em=511 nm).

HY-W356117

C6 NBD Glucosylceramide	Fluorescent Dyes/Probes
C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity.

HY-D0938

CFDA-SE 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester	Fluorescent Dyes/Probes
CFDA-SE (5(6)-Carboxyfluorescein diacetate succinimidyl ester) is an intracellular fluorescent dye which can track proliferating cells. Covalently bound CFDA-SE is divided equally between daughter cells, allowing discrimination of successive rounds of cell division.

HY-15626

ortho-iodoHoechst 33258
DNA Stain

ortho-iodoHoechst 33258 is part of a family of blue fluorescent dyes used to stain DNA.
HY-15629

HOE 32020
DNA Stain

HOE 32020 is a Hoechst stain, which is a blue fluorescent dyes used to stain DNA.
HY-15632

para-iodoHoechst 33258
DNA Stain

para-iodoHoechst 33258 is part of a family of blue fluorescent dyes used to stain DNA.

HY-W013435

1,2-Diaminoanthraquinone	Fluorescent Dyes/Probes
1,2-Diaminoanthraquinone is a sensitivity, specificity and nontoxic nitric oxide (NO) fluorescent probe. 1,2-Diaminoanthraquinone can be used to detect NO productions in live cell and animals with a maximum of absorption at about 540 nm and a detection limit of 5 μM for NO.

HY-117695

AQC 6-Aminoquinolyl-N-hydroxysccinimidyl carbamate	Fluorescent Dyes/Probes
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels.

HY-D1110

TFAX 594,SE	Fluorescent Dyes/Probes
TFAX 594,SE is a red fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 594,SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG).

HY-W402148

10-Methyl-9-(phenoxycarbonyl)acridinium (fluorosulfonate)	Fluorescent Dyes/Probes
10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate, a phenyl ester of acridinium esters, is a fluorescent dye that produces chemiluminescent under neutral conditions. 10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate can be used for the measurement of hydrogen peroxide.

HY-D1156A

HKSOX-1m (5/6-mixture) (hydrobromide)	Fluorescent Dyes/Probes
HKSOX-1m (5/6-mixture) hydrobromide is a O₂^•− fluorescent probe for mitochondria-targeting, exhibiting excellent selectivity and sensitivity toward O₂^•− over a broad range of pH, strong oxidants, and abundant reductants found in cells.

HY-D1113

TFAX 488,TFP	Fluorescent Dyes/Probes
TFAX 488,TFP is a green fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 488,TFP yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG, streptavidin).

HY-15625

Hoechst 33258 analog 3
DNA Stain

Hoechst 33258 analog 3 are part of a family of blue fluorescent dyes used to stain DNA.
HY-15561

HOE-S 785026
meta-Hoechst
DNA Stain

HOE-S 785026 is a blue fluorescent dyes, which can be used as a cell dye for DNA.
HY-15561B

HOE-S 785026 trihydrochloride
meta-Hoechst trihydrochloride
DNA Stain

HOE-S 785026 trihydrochloride is a blue fluorescent dyes, which can be used as a cell dye for DNA.
HY-15624

Hoechst 33258 analog 2
DNA Stain

Hoechst 33258 analog 2 are part of a family of blue fluorescent dyes used to stain DNA.

HY-D0055

3-Cyano-7-ethoxycoumarin	Chromogenic Substrates
3-Cyano-7-ethoxycoumarin is a fluorogenic cytochrome P-450 substrate that generates blue fluorescent product upon enzyme cleavage Target: Cytochrome P450 3-Cyano-7-ethoxycoumarin is a fluorescent probe useful in microsomal dealkylase studies.

HY-D1701

Mag-Fura-2 AM	Fluorescent Dyes/Probes
Mag-fura-2 AM is a membrane osmotic fluorescent indicator of intracellular magnesium. Mag-fura-2 AM can enter cells by incubation and is hydrolyzed to Mag-fura-2 by cellular esterases. (λ_ex=340 nm, λ_em=510 nm).

HY-114354

BODIPY FL alkyne BOD FL alkyne	Fluorescent Dyes/Probes
BODIPY FL alkyne (BOD FL alkyne) is a green-fluorescent dye (Ex=503 nm; Em=512 nm), a bright and photostable fluorophore which emits in fluorescein (FAM) channel. BODIPY FL alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.

HY-D0152

Tetramethylrhodamine-6-maleimide	Fluorescent Dyes/Probes
Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time.

HY-D1633

4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate	Fluorescent Dyes/Probes
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase.

HY-D1702

Mag-Fura-2 tetrapotassium	Fluorescent Dyes/Probes
Mag-Fura-2 tetrapotassium is a UV excitable rational fluorescent Mg²⁺/Ca²⁺ indicator (Ex=334-360 nm, Em=510 nm). Mag-Fura-2 tetrapotassium can be used for the determination of Mg²⁺ and Ca²⁺ concentrations.

HY-D1633A

4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium	Fluorescent Dyes/Probes
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase.

HY-D1541

Sulfo-Cyanine5.5 alkyne	Fluorescent Dyes/Probes
Sulfo-Cyanine5.5 alkyne, a near-infrared (NIR) fluorescent dye, is an alkyne modified Sulfo-Cyanine5.5 (Ex=67 8nm, Em=694 nm). Sulfo-Cyanine5.5 alkyne can react with azides for Click Chemistry labeling.

HY-110257

BDY FL-X, SE	Fluorescent Dyes/Probes
BODIPY FL-X,SE is a fluorescent green dye for the labeling of amine, shows a high fluorescence quantum yield and is relatively insensitive to pH change. BODIPY FL-X,SE can be used as an alternative for FAM, Cy2 or FITC. λ_abs: 504 nm; λ_em:510 nm.

HY-D0154

6-TRITC Tetramethylrhodamine-6-isothiocyanate	Fluorescent Dyes/Probes
Tetramethylrhodamine-6-isothiocyanate is a potent fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as an probe for haptenated proteins/peptides for the research of contact allergy. Tetramethylrhodamine-6-isothiocyanate can be used as a tracer for the confocal imaging in living cells.

HY-D1114

TFAX 488,SE dilithium	Fluorescent Dyes/Probes
TFAX 488,SE dilithium is a green fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 488,SE dilithium yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG, streptavidin).

HY-D1476

4-(2-Carboxyphenyl)-7-diethylamino-2-(7-diethylamino-2-oxochroman-3-yl)-chromylium perchlorate	Fluorescent Dyes/Probes
4-(2-Carboxyphenyl)-7-diethylamino-2-(7-diethylamino-2-oxochroman-3-yl)-chromylium perchlorate is a carboxyl functionalized organic fluorescent dye (λ_ex~650 nm, λ_em~690 nm).

HY-151756

diSulfo-Cy3 alkyne	Fluorescent Dyes/Probes
diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an azide group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase.

HY-W094758A

4-Di-1-ASP	Fluorescent Dyes/Probes
4-Di-1-ASP is a styryl dye used to stain glioma cells in living brain tissue for analysis of cell structure, viability, proliferation and endocytosis, cytokinesis and phagocytosis, as well as for observation of mitochondrial structures in living cells. 4-Di-1-ASP fluoresces green when imaged microscopically (λ_ex /λ_em = 475/606 nm) .

HY-W337618

7-Aminocoumarin	Fluorescent Dyes/Probes
7-Aminocoumarin is a pH-insensitive blue fluorophore. 7-Aminocoumarin is widely used as laser dyes in the blue-green region. 7-Aminocoumarin can be used to tag recombinant proteins on the cell surface and inside living cells through PRIME (probe incorporation mediated by enzymes). 7-Aminocoumarin can be visualized in acidic organelles such as endosomes.

HY-D1631

Calcium Green-5N AM	Fluorescent Dyes/Probes
Calcium Green-5N AM is a novel Ca²⁺-sensitive fluorescent probe. Calcium Green-5N AM shows enhancement in fluorescence intensity on binding Ca²⁺, and can monitor free Ca²⁺ in neurons.

HY-D0943

Nuclear Fast Red Helio Fast Rubine BBL	Fluorescent Dyes/Probes
Nuclear Fast Red, an anthraquinone dye, is commonly used in conjunction with an excess of aluminum ions as a red nuclear counterstain. Nuclear fast red has been used as a histochemical and colorimetric reagent for calcium. Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine.

HY-D0025

7-Amino-4-methylcoumarin-3-acetic acid	Fluorescent Dyes/Probes
7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm).

HY-D1700

Mag-indo-1/AM	Fluorescent Dyes/Probes
Mag-indo-1/AM is a cell-permeable fluorescent indicator for Mg²⁺ and also for Ca²⁺ (Ex=340-390 nm, Em=410-490 nm). Mag-indo-1/AM can be used to determine intracellular Mg²⁺ and Ca²⁺ concentrations.

HY-117401

5-Dodecanoylaminofluorescein	Fluorescent Dyes/Probes
5-Dodecanoylaminofluorescein, a lipophilic fluorescent probe, is a free-fatty-acid conjugate of fluorescein. 5-Dodecanoylaminofluorescein has been used in membrane fluidity studies and the determination of critical micelle concentration of detergents. 5-Dodecanoylaminofluorescein can be also used to synthesize hydrophobic nanospheres for drug delivery.

HY-D1486

4,4-Difluoro-8-(4'-iodophenyl)-1,7-bis-(1'-napthyl)-4-bora-3alpha,4alpha-diaza-s-indacene	Fluorescent Dyes/Probes
4,4-Difluoro-8-(4'-iodophenyl)-1,7-bis-(1'-napthyl)-4-bora-3alpha,4alpha-diaza-s-indacene is a fluorescent dye for DNA sequencing.

HY-126839

C12FDG 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside	Fluorescent Dyes/Probes
C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than FDG (HY-101895) for beta-galactosidase activity determinations in animal cells.

HY-D1296

Green DND-26	Fluorescent Dyes/Probes
Green DND-26 is used to mark acidic lysosomes to determine the cellular distribution. Green DND-26 is a fluorescent dye that stains acidic compartments in live cells and has been shown to selectively accumulate in lamellar bodies in alveolar type II (AT2) cells in the lung.

HY-D1584

C12 NBD Sphingomyelin	Fluorescent Dyes/Probes
C12 NBD sphingomyelin is an active derivative of sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm).

HY-W011664

1,3-Diphenylisobenzofuran DPBF	Fluorescent Dyes/Probes
1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe which possesses a highly specific reactivity towards singlet oxygen (¹O₂) forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran can detect the generation of reactive oxygen species (ROS).

HY-D1275

CAY10731	Fluorescent Dyes/Probes
CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H₂S). CAY10731 is used to monitor exo- and endogenous H₂S in both cancer and normal cells. CAY10731 is applied for imaging of H₂S in living tissues at variable depths and in nematodes.

HY-130735

Janelia Fluor® 646, SE JF646, SE; JF646, NHS	Fluorescent Dyes/Probes
Janelia Fluor® 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1156

HKSOX-1m (5/6-mixture)	Fluorescent Dyes/Probes
HKSOX-1m (5/6-mixture) is a O₂^•− fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O₂^•− over a broad range of pH, strong oxidants, and abundant reductants found in cells.

HY-W012642

2-Aminopurine	Fluorescent Dyes/Probes
2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics.

HY-150978

DDAO-C6	Fluorescent Dyes/Probes
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm).

HY-D0113

7-Hydroxy-4-methyl-2(1H)-quinolone	Fluorescent Dyes/Probes
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage.

HY-D0042

NBD-Cl
NBD chloride
Dyes

NBD-Cl is a nonfluorescent reagent which becomes highly fluorescent after reaction with thiol or amino groups.
HY-D0832

CY5-N3
Sulfo-Cyanine5-azide
Protein Labeling

CY5-N3 is a Cy5-azide, which is a fluorescent dye.
HY-P1093

Ac-LEHD-AFC
Chromogenic Substrates

Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase.

HY-D1393

Pb:Ag2Se QDs Pb:Ag2Se	Quantum Dots
Pb:Ag2Se QDs (Pb:Ag2Se) is an effective biological probe in the second near-infrared window (NIR-II) that can be used in bioimaging with high tissue penetration depth and high spatiotemporal resolution.

HY-D0102

4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole ABD-F	Fluorescent Dyes/Probes
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent for the sensitive and specific detection of thiols. 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole has low fluorescence background, and good stability of fluorophor.

HY-131020

Janelia Fluor® 525, SE JF525, SE; JF525, NHS	Fluorescent Dyes/Probes
Janelia Fluor® 525, SE (JF525, SE) is a yellow fluorescent dye (Ex = 525 nm; Em = 549 nm). Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-15940

5(6)-Carboxyfluorescein 5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers	Fluorescent Dyes/Probes
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo.

HY-133876

4-Di-16-ASP DiA	Fluorescent Dyes/Probes
4-Di-16-ASP is a green fluorescent membrane dye. 4-Di-16-ASP is a lipophilic aminostyryl probe with a broad emission spectrum (can be detected with green, orange or even red filters). It is commonly used for neuronal membrane tracing (it diffuses faster than DiO).

HY-D1625

Cy5 DBCO chloride	Fluorescent Dyes/Probes
Cy5 DBCO chloride is an azide reaction probe and the addition of DBCO molecules allows the imaging of azide-labelled biomolecules by a copper-free “Click Chemistry” reaction.

HY-D1582

C12 NBD Phytoceramide
Chromogenic Substrates

C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity.

HY-D0974

Sulforhodamine B sodium salt Acid Red 52; Kiton Red 620	Dyes
Sulforhodamine B sodium salt is a fluorescent dye with uses spanning from laser-induced fluorescence (LIF) to the quantification of cellular proteins of cultured cells.

HY-D0053

6-ROX
6-Carboxy-X-rhodamine
Oligonucleotide Labeling

6-ROX is a fluorescent oligonucleotide marker, acts as an acceptor molecule coupled to 5-FAM as the donor in FRET imaging.
HY-15628

Hoechst 33258 analog 5
DNA Stain

Hoechst 33258 analog 5 is a analog of Hoechst stains, which are part of a family of blue fluorescent dyes used to stain DNA.

HY-D1259

NEP VDP-green (NEP)	Fluorescent Dyes/Probes
NEP (VDP-green (NEP)) is a turn-on fluorescent probe based on the intramolecular charge transfer (ICT) mechanism for sensing vicinal dithiol-containing proteins (VDPs). NEP exhibits high selectivity toward VDPs in live cells and in vivo and displays a strong green fluorescence signal (λ_ex/λ_em=430/535 nm). NEP has the potential for parkinsonism.

HY-D1157

HKPerox-2	Fluorescent Dyes/Probes
HKPerox-2 is an excellently selective and sensitive green fluorescent probe toward H₂O₂ over 30-fold other tested ROS/RNS in chemical and biological systems. HKPerox-2 is a O-methyl rhodol derivative and specifically recognize H₂O₂ based on a tandem payne/dakin reaction.

HY-D1682

NFQ1	Fluorescent Dyes/Probes
NFQ1 is a *non-fluorescent* quencher** (absorption wavelength: 474 nm), and is used for a new type of One Sample Fluorescence Resonance Energy Transfer (OS-FRET) method. OS-FRET enable measurement of unquenched donor emission in the same sample. NFQ1 shows broad absorption spectrum ensuring its utility as a dark acceptor for many donors.

HY-D0822

CY3
Sulfo-Cyanine3
Protein Labeling

Cy3 (Sulfo-Cyanine3) is an orange-fluorescent label for protein and nucleic acid (λ_ex=554, λ_em=568).
HY-133527

OG 488, SE
Oregon green 488 succinimidyl ester
Dyes

OG 488, SE (Oregon green 488 succinimidyl ester), a fluorescent pH indicator, has many applications in biochemistry and neurosciences.
HY-D0043

5(6)-ROX
5(6)-Carboxy-X-rhodamine
Oligonucleotide Labeling

5(6)-ROX is a nucleic acid fluorescent label which can be used as a reference dye for real-time polymerase chain reaction.

HY-138659

Janelia Fluor® 646, Tetrazine JF646, Tetrazine	Fluorescent Dyes/Probes
Janelia Fluor® 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1301

BODIPY 581/591 C11	Fluorescent Dyes/Probes
C11-BODIPY581/591 is a fluorescent ratio-probe of lipid oxidation. C11-BODIPY581/591 is often used for indexing lipid peroxidation and antioxidant efficacy in model membrane systems and living cells. C11-BODIPY581/591 is applied in the quantitation of ferroptosis.

HY-D1671

TRITC-DHPE	Fluorescent Dyes/Probes
TRITC-DHPE is a rhodamine-labeled glycerophosphate ethanolamine lipid, with head groups marked with bright red fluorescent TRITC dye (λEx/λEm=514/580 nm). TRITC-DHPE can be used for membrane fusion assay to trace lipid processing in intracellular phagocytosis. TRITC-DHPE can serves as an energy transfer receptor for NBD, BODIPY and fluorescein lipid probes.

HY-131024

Janelia Fluor® 549, Tetrazine JF549, Tetrazine	Fluorescent Dyes/Probes
Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-114879

DDAO	Fluorescent Dyes/Probes
DDAO is a promising near-infrared (NIR) *red fluorescent* probe** with tunable excitation wavelength (600-650 nm) and long emission wavelength (λem = 656 nm). DDAO can de desiged for detection of the activities of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterases.

HY-147114

3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin	Fluorescent Dyes/Probes
3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is a DNA uptake tracer, a pteridine-based fluorescent guanosine analogue. 3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is widely used in studies of DNA binding and dynamics, with an absorbance maximum at 350 nm and an emission maximum at 430 nm.

HY-131022

Janelia Fluor® 549 TFA JF549 TFA	Fluorescent Dyes/Probes
Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131021

Janelia Fluor® 549, Azide JF549, Azide	Fluorescent Dyes/Probes
Janelia Fluor® 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1547

1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylurea	Fluorescent Dyes/Probes
1-(3',6'-Bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)-3-phenylurea (compound 1a) can be used as a fast-responsive fluorescent gold ion probe for detection of gold ions in water and synthetic products.

HY-130736

Janelia Fluor® 549, SE JF549, SE; JF549, NHS	Fluorescent Dyes/Probes
Janelia Fluor® 549, SE (JF549, SE) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-15631

Hoechst 33258 analog 6
DNA Stain

Hoechst 33258 analog 6 is a anglog of Hoechst stains(Hoechst 33258), which are part of a family of blue fluorescent dyes used to stain DNA.

HY-D0017

Dansyl chloride DNSCl	Protein Labeling
Dansyl chloride is a reagent that reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green-fluorescent sulfonamide adducts.

HY-143218

TPE-MI

Tetraphenylethene maleimide

Fluorescent Dyes/Probes

TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells. TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin treatment of the malaria parasitesPlasmodium falciparum .

HY-133520

HBC620	Fluorescent Dyes/Probes
HBC620 is a HBC analog. HBC is nonfluorescent in solution, but emits strong fluorescence upon forming tight complex with Pepper RNA aptamer. HBC-Pepper complex can be used to visualize RNA dynamics in live cells.

HY-D0153

Tetramethylrhodamine-5-isothiocyanate	Fluorescent Dyes/Probes
Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles.

HY-D0059

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride DIB-Cl	Fluorescent Dyes/Probes
4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) is a fluorescent labeling reagent. 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride can be used for labeling amines and successfully being applied to determine stimulant amines by HPLC.

HY-131023

Janelia Fluor® 549, Maleimide TFA JF549, Maleimide TFA	Fluorescent Dyes/Probes
Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1578

C12FDGlcU	Fluorescent Dyes/Probes
C12FDGlcU is a lipophilic analog of fluorescein di-β-D-glucuronic acid. C12FDGlcU can be useful for the detection of β-glucuronidase (GUS) gene expression. C12FDGlcU can enter the cells and then be cleaved by β-glucuronidase, generating the yellow-colored, green-fluorescent fluorescein (Abs/Em of the reaction product: 495/518 nm).

HY-D0016

5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride CTC	Fluorescent Dyes/Probes
5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride (CTC) is a redox-sensitive red fluorescent dye. 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride can be used for detecting metabolic activity in microorganisms. The emission maximum of 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride is 602 nm.

HY-D1258

AC-green VDP-green	Fluorescent Dyes/Probes
AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λ_ex/λ_em=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes.

HY-D1687

Flubi-2	Fluorescent Dyes/Probes
Flubi-2 is a fluorescein-biotin based pH-ratio dye (Ex=480 nm, Em= 520-560 nm) with a pK value of 6.7. Flubi-2 is a hydrolysis product of Flubida-2 (non-fluorescent, membrane permeable). Flubi-2 can be used for pH determination of organelles of the secretory pathway (such as golgi apparatus and endoplasmic reticulum) in living cells.

HY-P3749

Mca-(ala7,lys(dnp)9)-bradykinin	Fluorescent Dyes/Probes
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage.

HY-D0971

Pyronin Y Pyronine G; C.I. 45005	Fluorescent Dyes/Probes
Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells.

HY-D1540

Cyanine5.5 amine Cy 5.5 amine; Lumiprobe Cy 5.5 amine	Fluorescent Dyes/Probes
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy.

HY-103240

Methoxy-X04
Dyes

Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques.

HY-W273413

4-Hydrazino-7-nitro-benzofurazan hydrazine adduct NBD-H	Fluorescent Dyes/Probes
4-Hydrazino-7-nitro-benzofurazan hydrazine adduct (NBD-H) is an indicator, which can embed in a soft, hydrophobic polymer matrix. 4-Hydrazino-7-nitro-benzofurazan hydrazine adduct forms highly fluorescent products with aldehydes via hydrazone formation. 4-Hydrazino-7-nitro-benzofurazan hydrazine adduct can be used for fluorogenic labelling of carbonylcompounds.

HY-15534

JC-1 CBIC2	Fluorescent Dyes/Probes
JC-1 (CBIC2) is a fluorescent lipophilic carbocyanine dye used to measure mitochondrial membrane potential. JC-1 forms complexes known as J-aggregates at high ΔΨm. Aggregates of JC-1 emit an orange-red fluorescence (Ex/Em=585/590 nm). While in cells with low ΔΨm, JC-1 remains in the monomeric form. JC-1 monomers emit a green fluorescence (Ex/Em=510/527 nm).

HY-128868

FITC-Dextran (MW 10000)

Fluorescent Dyes/Probes

FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption.

HY-D1585

BODIPY TR methyl ester

Fluorescent Dyes/Probes

BODIPY TR methyl ester is a lipophilic GFP Counterstain. BODIPY TR methyl ester dye readily permeates cell membranes and localizes in endomembranous organelles but not localize strongly in plasma membranes. BODIPY TR methyl ester is an excellent red fluorescent vital dye (Ex=568 nm, Em=625 nm), can be used to reveal the location and shapes of cell nuclei, the shapes of cells within embryonic tissues, as well as the bound aries of organ-forming tissues within the whole embryo.

HY-128868A

FITC-Dextran (MW 4000)

Fluorescent Dyes/Probes

FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption.

HY-W127715

Lucifer Yellow CH dipotassium

Fluorescent Dyes/Probes

Lucifer Yellow CH dipotassium is a highly fluorescent dye. Lucifer Yellow CH dipotassium can be viewed both in living tissue and after fixation and embedding. Lucifer Yellow CH dipotassium can be used for marking cells. Lucifer Yellow CH dipotassium spreads rapidly throughout an injected cell. Lucifer Yellow CH dipotassium has a great intrinsic tendency to spread from cell to cell (Ex/Em=430/540 nm).

HY-D0711

Indocyanine green Foxgreen; IC Green; Cardiogreen	Chromogenic Assays
Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography.

HY-D1066

NIR-Thiol dinitrobenzenesulfonate	Fluorescent Dyes/Probes
NIR-Thiol dinitrobenzenesulfonate has both absorption and emission in the NIR region. NIR-Thiol dinitrobenzenesulfonate responds to thiol with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-Thiol dinitrobenzenesulfonate is capable of imaging endogenously produced thiol in living cells and mice.

HY-D1323

Cyanine5.5 maleimide chloride Cy5.5 maleimide chloride	Dyes
Cyanine5.5 maleimide (Cy5.5 maleimide) chloride is a potent fluorescent dye. Cyanine5.5 maleimide can be used as a protein stain.

HY-138658

Janelia Fluor® 526, SE

JF526, SE; JF526, NHS

Fluorescent Dyes/Probes

Janelia Fluor® 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-131030

Janelia Fluor® 669, SE

JF669, SE; JF669, NHS

Fluorescent Dyes/Probes

Janelia Fluor® 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669−HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm). Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1632

4-MU-α-GlcNS sodium

Fluorescent Dyes/Probes

4-MU-α-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-α-GlcNH₂. 4-MU-α-GlcNH₂ can liberate 4-methylumbelliferone (4-MU, fluorescent product) via α-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-α-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches.

HY-131131

5-CFDA-AM

Fluorescent Dyes/Probes

5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell.

HY-D0717

DAF-FM DA Diaminofluorescein-FM diacetate	Chromogenic Assays
DAF-FM DA is a reagent to detect and quantify low concentrations of nitric oxide (NO); DAF-FM fluorescence can be detected by any instrument that can detect fluorescein, including flow cytometers, microscopes, fluorescent microplate readers and fluorometers.

HY-D1246

Ethidium monoazide bromide	DNA Stain
Ethidium monoazide bromide is a DNA intercalating fluorescent dye that enters bacteria with damaged membranes. Ethidium monoazide bromide can be covalently linked to DNA by photoactivation. Ethidium monoazide bromide stains only dead cells.

HY-131025

Janelia Fluor® 585, SE

JF585, SE; JF585, NHS

Fluorescent Dyes/Probes

Janelia Fluor® 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor® 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D0049

6-TAMRA-SE 6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester	Oligonucleotide Labeling
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing.

HY-D1583

Cyanine5 DBCO

DBCO-Cy5; Cyanine5 dibenzocyclooctyne

Fluorescent Dyes/Probes

Cyanine5 DBCO (DBCO-Cy5) is a water-soluble, low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm).

HY-D0952

Acridine Orange base

Fluorescent Dyes/Probes

Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays.

HY-D0988

R-Phycoerythrin	Dyes
R-Phycoerythrin is a phycobiliproteins could be isolated from Heterosiphonia japonica. R-Phycoerythrin is a potent fluorescent probe contains four chromophore-carrying subunits that exhibits extremely bright red-orange fluorescence. (λex=496 nm, λem=578 nm).

HY-D1020

7-Aminoactinomycin D 7-AAD	DNA Stain
7-Aminoactinomycin D (7-AAD) a fluorescent DNA stain, is a potent RNA polymerase inhibitor. 7-Aminoactinomycin D selectively binds to GC regions of the DNA. 7-Aminoactinomycin D also has antibacterial effects.

HY-D1325

Cyanine5.5 alkyne chloride	Dyes
Cyanine5.5 alkyne chloride, a near-infrared (NIR) fluorescent dye, is an alkyne modified Cyanine5.5 (Ex=680 nm, Em=710 nm). Cyanine5.5 alkyne chloride can react with azides for Click Chemistry labeling.

HY-P3110

Ac-DNLD-AMC	Dyes
Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity.

HY-D1670

Z-Gly-Pro-AMC	Chromogenic Substrates
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-amido-4-methylcoumarin (HY-D0027). (λ_ex=380 nm, λ_em=465 nm).

HY-D1575

C6 NBD Galactosylceramide	Dyes
C6 NBD galactosylceramide is an active derivative of galactosylceramide that is tagged with fluorescent C6 nitrobenzoxadiazole (C6 NBD). C6 NBD galactosylceramide can be used as a substrate for neutral β-glycosylceramidase (GCase) to study intracellular localization and metabolism of galactosylceramide (Ex=nm, Em=525).

HY-D1600

Sulfo-Cyanine5.5 maleimide potassium	Dyes
Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers.

HY-D1308

Sulfo-Cyanine5.5 azide tripotassium	Dyes
Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling.

HY-131010

Flutax-2 (5/6-mixture)	Dyes
Flutax-2 (5/6-mixture) is an active fluorescent derivative of Taxol. Flutax-2 (5/6-mixture) binds to polymerized α,β-tubulin dimers. Flutax-2 (5/6-mixture) is able to stabilize microtubules of intact T. gallinae and T. foetus trophozoites^[1].

HY-D1509

Phenazine ethosulfate	Dyes
Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid.

HY-133521

HBC599	Dyes
HBC599 is a HBC analog. HBC is nonfluorescent in solution, but emits strong fluorescence upon forming tight complex with Pepper RNA aptamer. HBC-Pepper complex can be used to visualize RNA dynamics in live cells.

HY-133536

PA Janelia Fluor® 549, SE PA-JF549-NHS	Dyes
PA Janelia Fluor® 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549,SE (JF549,NHS). JF549,SE (JF549,NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1030

Fluorescein Biotin	Fluorescent Dyes/Probes
Fluorescein Biotin is used as an alternative to radioactive biotin for detecting and quantitating biotin-binding sites by either fluorescence or absorbance; the the fluorescence or absorbance of Fluorescein Biotin is quenched, upon binding to avidin or streptavidin.

HY-D1646

BDP TR methyltetrazine
Fluorescent Dyes/Probes

BDP TR methyltetrazine is a BDP dye linker containing a methyltetrazine group.

HY-D1027

Dansylcadaverine Monodansyl cadaverine	Fluorescent Dyes/Probes
Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands.

HY-137844

L-Leucine-7-amido-4-methylcoumarin hydrochloride Leu-AMC hydrochloride	Fluorescent Dyes/Probes
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro.

HY-B1533A

Anazolene trisodium
Fluorescent Dyes/Probes

Anazolene trisodium is an anionic dye, a textile azo dye with a maximum absorption wavelength of λ_max = 571 nm.
HY-136937

PYBG-TMR
Fluorescent Dyes/Probes

PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells.

HY-112803

GNE-371	Fluorescent Dyes/Probes
GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like, with an IC₅₀ of 10 nM for TAF1(2).

HY-D1260

FM-red PSH-red	Fluorescent Dyes/Probes
FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx).

HY-D1659

BDP 581/591 alkyne
Fluorescent Dyes/Probes

BDP 581/591 alkyne is a moderately hydrophobic borondipyrromethene fluorophore.

HY-D1639

5,5'-Dibromo BAPTA tetrapotassium	Fluorescent Dyes/Probes
5,5'-Dibromo BAPTA tetrapotassium is a calcium chelator, can be formulated into a buffer with a defined calcium ion concentration. 5,5'-Dibromo BAPTA tetrapotassium can control the concentration of calcium ions inside and outside the cell and can be used in studies of calcium physiological activity.

HY-D1622

Cyanine3 DBCO hexafluorophosphate Cy3-DBCO hexafluorophosphate	Fluorescent Dyes/Probes
Cyanine3 DBCO (Cy3-DBCO) hexafluorophosphate is a azide reactive probe, for imaging azide-labeled biomolecules via a copper-free "click-through" reaction.

HY-D1345

SiR-COOH
Fluorescent Dyes/Probes

SiR-COOH could be used to follow the intracellular location of the model therapeutic drug in GFP cells (Abs, 645 nm; Em, 676 nm).
HY-W040230

Acrylodan
Fluorescent Dyes/Probes

Acrylodan, reacted with thiols, is sensitive to the local environmental dipolarity and dynamics within the binding pocket surrounding Cys³⁴.

HY-114350

BDP FL maleimide	Fluorescent Dyes/Probes
BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy.

HY-D1619

Cyanine3 hydrazide dichloride	Fluorescent Dyes/Probes
Cyanine3 hydrazide dichloride is a carbonyl reactive dye. Cyanine3 hydrazide dichloride allows the labelling of various carbonyl-containing molecules such as antibodies and other glycoproteins after oxidation by periodate, proteins or reducing sugars after oxidative stress or deamination.

HY-D1435

Oxonol VI	Fluorescent Dyes/Probes
Oxonol VI acts as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is suitable for detecting changes of membrane potential associated with the activity of the (Na⁺ + K⁺)-ATPase in reconstituted vesicles.

HY-D1434

FM1-43	Fluorescent Dyes/Probes
FM1-43, a styryl dye used to study endocytosis and exocytosis, behaves as a permeant blocker of the hair-cell mechanotransducer channel. FM1-43 also reduces the ototoxic effects of the aminoglycoside antibiotic neomycin sulfate.

HY-D1621

3-NBD-C12 Cholesterol	Fluorescent Dyes/Probes
C-12 NBD cholesterol is a cholesterol derivative with a hydrophilic fluorophore tag (NBD: Ex=465 nm, Em=535 nm). C-12 NBD cholesterol can be used to study the utilization and metabolism of cholesterol.

HY-135641

Biotin-probe 1
Fluorescent Dyes/Probes

Biotin-probe 1 is a non-radiolabeled probe. Biotin-labeled probes can be applied to in situ hybridization.

HY-D1536

Glycine cresol red	Fluorescent Dyes/Probes
Glycine cresol red is a complexometric indicator. Glycine cresol red forms coloured complexes with Al³⁺, Ga³⁺ and In³⁺ ions in aqueous solutions. Glycine cresol red can been used for the spectrophotometric determination of inorganic ions. Glycine cresol red can be used as a stain in neurohistology.

HY-W154295

Purple-β-D-Gal	Fluorescent Dyes/Probes
Purple-β-D-Gal is a chromogenic β-galactosidase substrate. Intracellular enzymatic hydrolysis of Purple-β-D-Gal generates free indoxyl molecules, which undergo in situ oxidation and subsequent dimerization to produce chromogenic, water-insoluble, indigo precipitates. Purple-β-D-Gal can be used for the detection of β-galactosidase activity.

HY-151751

BDP TMR alkyne	Fluorescent Dyes/Probes
BDP TMR alkyne is an alkyne-containing click chemistry reagent that can click chemistry with azides. BDP TMR alkyne has the fluorophore BDP and can be used for oligonucleotide labeling and amino acid sequencing.

HY-D1689

Rf470DL
Fluorescent Dyes/Probes

Rf470DL is a rotor-fluorogenic D-amino acid (RfDAA). Rf470DL can be used for labeling bacteria (Ex=470 nm, Em=640 nm).

HY-D1704

Bodipy TMR-X muscimol	Fluorescent Dyes/Probes
Bodipy TMR-X muscimol is a Bodipy labeled Muscimol (HY-N2313) (Ex=543 nm, Em=572 nm). Muscimol is a GABAA agonist. Bodipy TMR-X muscimol can be used for imaging the spread of reversible brain inactivations.

HY-133852

FD-1080
Fluorescent Dyes/Probes

FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging.

HY-D1416

HMBR	Fluorescent Dyes/Probes
HMBR, an analog bearing an additional methyl group on the aromatic ring, is nonfluorescent by itself, but it fluoresces yellow light upon blue-light excitation when bound to Y-FAST. HMBR is nontoxic for zebrafish embryos. cell-permeant.

HY-D1045A

Dabcyl acid sodium DABCYL sodium; Para-methyl red sodium	Fluorescent Dyes/Probes
Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions.

HY-P3362

Ac-IETD-AMC	Fluorescent Dyes/Probes
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity.

HY-W414380

Bdp tr nhs ester

Fluorescent Dyes/Probes

Bdp tr nhs ester is a chemiluminescent coupling compound with a long excited state lifetime for immunoassays and is suitable for microscopy and fluorescence polarization analysis applications. NHS ester can react specifically and efficiently with the side chains of primary amines such as lysine residues or amino silane coated surfaces under neutral or weakly basic conditions to form covalent bonds.

HY-111382

Diphenylterazine DTZ	Fluorescent Dyes/Probes
Diphenylterazine (DTZ) is a bioluminescence agent. Diphenylterazine alone yielded very little background, leading to excellent signal-to-background ratios.

HY-D1477

5(6)-Carboxyfluorescein diisobutyrate	Fluorescent Dyes/Probes
5(6)-Carboxyfluorescein diisobutyrate is a protected 5(6)-carboxyfluorescein. 5(6)-carboxyfluorescein is a fluorescence pH indicator.

HY-D1669

Biotin-11-UTP	Fluorescent Dyes/Probes
Biotin-11-UTP is a Biotin-labeled uridine triphosphate (UTP), containing 11 atoms in the linker between biotin and UTP. Biotin-11-UTP can biotinylate transcribed RNA in vitro and has been widely used as labeling RNA probe.

HY-111956

D-Ala-Lys-AMCA	Fluorescent Dyes/Probes
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis.

HY-D1553

BODIPY-C12	Fluorescent Dyes/Probes
BODIPY-C12 is a boron-dipyrromethene derivative containing a lipophilic tail (excitation 490 nm). BODIPY-C12 is a hydrophobic molecular and sensitivity to the surrounding environment and can be used for quantify viscosity.

HY-P1986

Z-DEVD-AFC	Fluorescent Dyes/Probes
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity.

HY-D1348

BDP R6G alkyne	Fluorescent Dyes/Probes
BDP R6G alkyne is an alkyne modified BDP R6G. BDP R6G is a bright and photostable dye (BDP R6G: Ex=530 nm, Em=545 nm). BDP R6G alkyne can be used for labeling using Click chemistry.

HY-D0825

CY7 Sulfo-Cyanine7	Fluorescent Dyes/Probes
Cy7 (Sulfo-Cyanine7) is a fluorescence labeling agent (Ex=750 nm, Em=773 nm). Cyanine dyes are used to label proteins, antibodies, peptides, and oligonucleotides.

HY-D1693

FBBBE	Fluorescent Dyes/Probes
FBBBE is used to detect the production of H₂O₂ by cells. FBBBE can be triggered by intracellular H₂O₂ and converted to fluorescein, resulting in an increase in intracellular fluorescence (Ex=4480 nm, Em=512 nm).

HY-138200

Cy5 maleimide Cyanine5 maleimide	Fluorescent Dyes/Probes
Cy5 maleimide is a highly sensitive fluorescence dye, which can be used for labeling protein, antibody, nucleic acid molecule and so on.

HY-110251A

DFHBI-2T
Fluorescent Dyes/Probes

DFHBI-2T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=500 nm/523 nm). DFHBI-2T is used to image RNA in live cells.

HY-D0156

ZnAF-1	Fluorescent Dyes/Probes
ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry.

HY-W013275

MCLA hydrochloride
Fluorescent Dyes/Probes

MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.

HY-138760

SEluc-2	Fluorescent Dyes/Probes
SEluc-2 is a small-molecule probe based on the firefly luciferin. SEluc-2, a bioluminescent probe for the sensitive and selective detection of thiols in living cells.

HY-D1667

BDP 558/568 hydrazide	Fluorescent Dyes/Probes
BDP 558/568 hydrazide is a carbonyl reactive hydrazide derivative of BDP 558/568 (BDP 558/568: Ex=558 nm, Em=568 nm). BDP 558/568 hydrazide can be used for the labeling of aldehydes or ketones.

HY-D0219A

Thymol Blue sodium	Fluorescent Dyes/Probes
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6.

HY-D1344

BDP 630/650 azide	Fluorescent Dyes/Probes
BDP 630/650 azide is a bright and photostable dye azide (BDP 630/650: Ex=630 nm, Em=650 nm). BDP 630/650 azide can be used for labeling using Click chemistry.

HY-D1566

Sulfo-Cy7.5 maleimide	Fluorescent Dyes/Probes
Sulfo-Cy7.5 maleimide is a cyanine dye. Sulfo-Cy7.5 maleimide is a near infrared fluorophore with absorption and emission ranges around 800 nm. Sulfo-Cy7.5 maleimide is highly hydrophilic. Sulfo-Cy7.5 maleimide can be used for the labeling of SH groups of proteins and peptides. Sulfo-Cyanine7.5 can be used for selective glucose recognition researchsup>[1].

HY-151644

Fluorescein hydrazide	Fluorescent Dyes/Probes
Fluorescein hydrazide is a colorimetric probe formed by the reaction of dihydrazine adipate with fluorescein isothiocyanate. Fluorescein hydrazide can be used to label aldehyde and ketone groups.

HY-151713

Sulfo-Cy3-Methyltetrazine	Fluorescent Dyes/Probes
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene.

HY-D1402

5MP-Fluorescein	Fluorescent Dyes/Probes
5MP-Fluorescein (compound 3e) is a fluorescein dye base on 5-Methylene pyrrolone (5MP).5-Methylene pyrrolones are highly thiol-specific and tracelessly removable bioconjugation tools.

HY-D1330

BDP R6G azide	Fluorescent Dyes/Probes
BDP R6G azide is an anlong of BDP dye. BDP R6G azide is available that are tuned to match excitation and emission channels of classical xanthene and cyanine dyes. BDP R6G azide can be used in copper-catalyzed Click chemistry reactions with alkynes, DBCO and BCN. (λ_ex=530 nm, λ_em=548 nm).

HY-P2208

Z-IETD-AFC
Fluorescent Dyes/Probes

Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity.

HY-15922A

Luminol sodium salt	Fluorescent Dyes/Probes
Luminol sodium salt is a chemical that exhibits chemiluminescence with pK_a values of 6.74 and 15.1. Luminol sodium salt exhibits chemiluminescence (CL) at 425 nm λ_max. Luminol sodium salt is commonly used in forensics as a diagnostic tool for the detection of blood stains.

HY-D1363

BDP R6G maleimide	Fluorescent Dyes/Probes
BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds.

HY-D0985A

TMRE
Tetramethylrhodamine ethyl ester perchlorate
Fluorescent Dyes/Probes

TMRE is a mitochondria specific dye (λ_ex=550 nm, λ_em=575 nm).

HY-D0802

Biotin NHS Biotin-NHS; Biotin N-hydroxysuccinimide ester; NHS-Biotin	Fluorescent Dyes/Probes
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.

HY-D1662

BDP 558/568 NHS ester BODIPY 558/568SE	Fluorescent Dyes/Probes
BDP 558/568 NHS ester is a borondipyrromethene fluorophore with emission in the yellow part of the spectrum. BDP 558/568 NHS ester is an amine reactive NHS ester, and the absorption and emission spectra of BDP 558/568 NHS ester are similar with TAMRA, BDP TMR, Cyanine3, and sulfo-Cyanine3.

HY-111956B

D-Ala-Lys-AMCA hydrochloride	Fluorescent Dyes/Probes
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis.

HY-D0082

7-Diethylamino-4-methylcoumarin
Fluorescent Dyes/Probes

7-Diethylamino-4-methylcoumarin is a laser dye.

HY-15942

5-TAMRA	Fluorescent Dyes/Probes
5-TAMRA (5-Carboxytetramethylrhodamine), SE and its conjugates yield bright, pH-insensitive orange-red fluorescence (approximate excitation/emission maxima ~546/579) with good photostability.

HY-D1368

BDP FL amine hydrochloride	Fluorescent Dyes/Probes
BDP FL amine hydrochloride is a borondipyrromethene dye with good water solubility. BDP FL amine hydrochloride can be read on the FAM channel.

HY-D0056

5-Carboxyfluorescein diacetate N-succinimidyl ester	Fluorescent Dyes/Probes
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell permeable dye (Ex=492 nm, Em=517 nm). 5-Carboxyfluorescein diacetate N-succinimidyl ester can label cells by covalently binding to intracellular molecules. 5-Carboxyfluorescein diacetate N-succinimidyl ester is used to track lymphocyte migration and proliferation.

HY-D1424

Coelenterazine hcp	Fluorescent Dyes/Probes
Coelenterazine hcp is a Coelenterazine analogue. Coelenterazine hcp shows high sensitivity to Ca²⁺. Coelenterazine hcp is suited for monitoring intracellular Ca²⁺.

HY-D1688

Flubida-2	Fluorescent Dyes/Probes
Flubida-2 is a cell permeable dye which can be hydrolyzed to Fubi-2 by endoesterases in cells (after hydrolysis, Ex=492 nm, Em=517 nm). Flubida-2 can be used to detect pH at a specific site in a cell organelle by directing the probe to where avidin fusion proteins are located.

HY-151755

Sulfo-Cy3-Tetrazine	Fluorescent Dyes/Probes
Sulfo-Cy3-Tetrazine is a click chemistry reagent containing an tetrazine group. Sulfo-Cy3-Tetrazine is water soluble cyanine fluorescence dye, which is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefin.

HY-D0903

1,8-Diazafluoren-9-one
DFO
Fluorescent Dyes/Probes

1,8-Diazafluoren-9-one (DFO) is a chemical that is used to find fingerprints on porous surfaces.
HY-D0807

5-IAF
5-Iodoacetamidofluorescein
Fluorescent Dyes/Probes

5-IAF is an idoacetamide derivate of fluoresceine.

HY-130768

N-(Azido-PEG3)-N-Fluorescein-PEG3-acid	Fluorescent Dyes/Probes
N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker which contains azide, fluorescein and carboxylic acid moieties.

HY-D1706

AMCA-6-dUTP
Fluorescent Dyes/Probes

AMCA-6-dUTP can be used for enzymatic labeling of DNA/cDNA.
HY-59021

2-(4-Biphenylyl)-5-phenyl-1,3,4-oxadiazole
Fluorescent Dyes/Probes

2-(4-Biphenylyl)-5-phenyl-1,3,4-oxadiazole is a laser dyes with high photoluminescence (PL) quantum efficiency.
HY-D0211

Phenolphthalein
Fluorescent Dyes/Probes

Phenolphthalein is a widely applied but toxic indicator dye.

HY-111956A

D-Ala-Lys-AMCA TFA	Fluorescent Dyes/Probes
D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis.

HY-135414A

Cyanine5 NHS ester bromide	Fluorescent Dyes/Probes
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues.

HY-101900

Nile Blue A sulfate Nile blue sulfate	Fluorescent Dyes/Probes
Nile Blue A (Nile blue sulfate) is used to differentiate melanins and lipofuscins. It is also useful for staining fats and preparation of an amperometric glucose sensor.

HY-D1655

BDP 581/591 DBCO	Fluorescent Dyes/Probes
BDP 581/591 DBCO is a borondipyrromethene dye with a conjugated olefin system (Ex=585 nm, Em=594 nm). BDP 581/591 DBCO can be used as a conventional fluorophore or for the detection of ROS (after oxidation, fluorescence moves to the green part of the spectrum).

HY-101880

ADHP
10-Acetyl-3,7-dihydroxyphenoxazine
Fluorescent Dyes/Probes

ADHP is a fluorogenic peroxidase substrate (λ_ex=530 nm, λ_em=590 nm).
HY-D1080

EDANS
1,5-EDANS
Fluorescent Dyes/Probes

EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET).

HY-135367

pyCTZ Pyridyl CTZ	Fluorescent Dyes/Probes
pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing.

HY-101893

Dihydrofluorescein diacetate	Fluorescent Dyes/Probes
Dihydrofluorescein diacetate is a fluorimetric probe mainly used for oxidative stress measurements, in both cell-free systems and cellular models.

HY-W127705

Quinacrine mustard dihydrochloride	Fluorescent Dyes/Probes
Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes.

HY-D1148

HKGreen-4I	Fluorescent Dyes/Probes
HKGreen-4I is a diarylamine-based fluorogenic probe extracted from patent US9651528B2, compound 7. HKGreen-4I is used for detection of peroxynitrite (ONOO^-).

HY-W073524

DFAME

Fluorescent Dyes/Probes

DFAME is a red fluorophore (Ex=508 nm, Em=641 nm). Beetroot and Corn are dimeric fluorogenic RNA aptamers that can bind to DFAME to form Beetroot-DFAME (K_d=460nM) and Corn-DFAME (K_d= 3600nM). Beetroot-DFAME (Kd=460nM) and Corn-DFAME can be used to form RNA assemblies in living cells. Creating RNA assemblies can be used for the study of RNA Nanostructures. DNA/RNA Nanostructures would be useful in cell and gene therapy (CGT) research.

HY-D1043

1,4-Dichloro 6-carboxytetramethylrhodamine
Fluorescent Dyes/Probes

1,4-Dichloro 6-carboxytetramethylrhodamine is a fluorescence labeling agent (Ex=541 nm, Em=568 nm).

HY-D0720

Lucigenin NSC-151912; L-6868	Fluorescent Dyes/Probes
Lucigenin(L-6868; NSC-151912) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.

HY-110251

DFHBI-1T	Fluorescent Dyes/Probes
DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells.

HY-P1169

Ac-IETD-AFC
Fluorescent Dyes/Probes

Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B.

HY-D1649

BDP R6G amine	Fluorescent Dyes/Probes
BDP R6G amine is a fluorophore based on borondipyrromethene scaffold. BDP R6G amine is a BDP linker containing an amine group. BDP R6G amine is a terminal alkyne for copper-catalyzed Click chemistry. (λ_ex=530 nm, λ_em=548 nm).

HY-D1676

Thymolphthalein monophosphate disodium hydrate	Fluorescent Dyes/Probes
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum.

HY-D1629

Calcium Orange AM	Fluorescent Dyes/Probes
Calcium Orange AM is an intracellular calcium reporter. Specific fluorescence can be detected when free calcium binds to Calcium Orange AM (Ex/Em=549/576 nm). Calcium Orange AM does not enter the vacuoles and does not compartmentalize into acidic vesicles.

HY-D0983

Trypan red
C.I. 22850
Fluorescent Dyes/Probes

Trypan red is a vital stain.

HY-D0226

Quinizarin 1,4-Dihydroxyanthraquinone	Fluorescent Dyes/Probes
Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (K_d=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth.

HY-D1118

BODIPY 576/589
Fluorescent Dyes/Probes

BODIPY 576/589 is a long wavelength biological labeled dye.
HY-D0936

SPQ
Fluorescent Dyes/Probes

SPQ is being used to examine and measure membrane chloride transport mechanisms.

HY-D1169

BDP R6G carboxylic acid	Fluorescent Dyes/Probes
BDP R6G carboxylic acid is a borondipyrromethene dye (Excitation: 530 nM; Emission: 548 nM). BDP R6G carboxylic acid terminal carboxylic acid can react with primary amine groups in the presence of activators to form a stable amide bond, for subsequent labeling reactions like Steglich esterification.

HY-D1588

BODIPY-X-Alkyne	Fluorescent Dyes/Probes
BODIPY-X-Alkyne is an alkyne-modified BODIPY derivative (Ex=526 nm, Em=540 nm). BODIPY-X-Alkyne can react with azides via a copper-catalyzed click reaction.

HY-W297715

7-Acetoxy-4-bromomethylcoumarin
Fluorescent Dyes/Probes

7-Acetoxy-4-bromomethylcoumarin acts as a fluorescence label for fatty acids.

HY-151537

Gol-NTR	Fluorescent Dyes/Probes
Gol-NTR is a Golgi-targetable probe with high selectivity and sensitivity. Gol-NTR is Nitroreductase (NTR)-activated and has visualization acute lung injury (ALI) and repair function. Gol-NTR can be used for the research for monitoring and assessing treatment response of sepsis-induced ALI.

HY-D1543

Pyronin B	Fluorescent Dyes/Probes
Pyronin B is an organic cationic dye used for the staining of bacteria, mycobacteria and ribonucleic acids. Pyronin B is also used as a small hydrophobic (SH) protein channel inhibitor.

HY-D1250

Mito-TRFS
Fluorescent Dyes/Probes

Mito-TRFS, the first off-on probe, is used to image the mitochondrial thioredoxin reductase (TrxR2) in live cells.
HY-136865

MeOSuc-AAPV-AMC
Fluorescent Dyes/Probes

MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (K_m: 362 μM, Ex=380 nm, Em=460 nm).
HY-D0022A

6-Aminofluorescein
6-AF
Fluorescent Dyes/Probes

6-Aminofluorescein (6-AF) is a new fluorescence marker.

HY-D1650

BDP 630/650 carboxylic acid	Fluorescent Dyes/Probes
BDP 630/650 carboxylic acid is a bright far-red fluorophore based on a borondipyrromethene scaffold. BDP 630/650 carboxylic acid is a BDP linker containing carboxylic acid. BDP 630/650 carboxylic acid can react with primary amine groups to form a stable amide bond. (λ_ex=630 nm, λ_em=650 nm).

HY-D1562

CytoTrace Red CMTPX
Fluorescent Dyes/Probes

CytoTrace Red CMTPX is a cell permeable long-term cell tracer (Ex=577 nm, Em=602 nm).

HY-D1050

DNP-X, SE 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester	Fluorescent Dyes/Probes
DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester), the DNP-X acid modified by succinimidyl ester, is an amine-reactive building block for developing a probe, which can be recognized by anti-DNP antibodies. DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.

HY-W127769

Rose-β-D-Gal	Fluorescent Dyes/Probes
Rose-β-D-Gal is a flurescent dye, is also a β-galactosidase substrate. Rose-β-D-Gal creates a pink/magenta color after the reaction and has been used for detection of β-gal activity.

HY-143285

AMC-GlcNAc

Fluorescent Dyes/Probes

AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate.

HY-D1053

CY7-N3
Sulfo-Cyanine7-N3
Fluorescent Dyes/Probes

CY7-N3 (Sulfo-Cyanine7-N3) is a water-soluble NIR dye azide for Click Chemistry.

HY-136936

PYBG-BODIPY	Fluorescent Dyes/Probes
PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells.

HY-W127716

Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2	Fluorescent Dyes/Probes
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs).

HY-P2270

Phalloidin-TRITC	Fluorescent Dyes/Probes
Phalloidin-TRITC is a TRITC labeled, red fluorescence probe for F-actin. Phalloidin, bound to actin filaments, reacts covalently with amino acids Glu-llT, Met-ll9, and Met355, which are very close to the nucleotide binding site.

HY-D1052

Cy7-YNE
Fluorescent Dyes/Probes

Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides.

HY-D1442

SBFI tetraammonium	Fluorescent Dyes/Probes
SBFI (tetraammonium), the tetraammonium salt of SBFI, is a sodium fluorescence indicator. SBFI (tetraammonium) is sodium-sensitive dye. The excitation wavelength is set 333 nm, and the emission wavelength is 539 nm for SBFI.

HY-134435

Z-Arg-AMC hydrochloride	Fluorescent Dyes/Probes
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm).

HY-D0029

5(6)-Aminofluorescein 5(6)-AFM; Fluoresceinamine mixed isomers	Fluorescent Dyes/Probes
5(6)-Aminofluorescein (5(6)-AFM) is a a precursor for synthesis of 5(6)-FITC (HY-15941). 5(6)-FITC is an amine-reactive derivative of fluorescein dye.

HY-D0162

Malachite green oxalate	Fluorescent Dyes/Probes
Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green oxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green oxalate exhibits antitumor activity in vitro and in vivo.

HY-W103047

1-Pyrenebutyric acid	Fluorescent Dyes/Probes
1-Pyrenebutyric acid is a fluorescence probe that can be used in fluorescence determination of DNA. 1-Pyrenebutyric acid can be used as a linker for biomolecules to form a self-assembled monolayer on grapheme.

HY-D1620

H2TPTBP
Fluorescent Dyes/Probes

H2TPTBP is a small molecule ion indicator.

HY-D1627

CellTracker CM-DiI CM-DiI	Fluorescent Dyes/Probes
CellTracker CM-DiI (CM-DiI) is a lipophilic fluorochrome that can be used for tracking the migration of lymphocytes. CellTracker CM-DiI is feasible to detect labeled cells in histological sections (excitation 553 nm; emission 570 nm).

HY-123051

Ac-WLA-AMC
Fluorescent Dyes/Probes

Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate.

HY-150979

Gd-NMC-3	Fluorescent Dyes/Probes
Gd-NMC-3 is a near-infrared fluorescence/magnetic resonance (NIRF/MR) bimodal imaging probe. Gd-NMC-3 shows high resolution and sensitivity in tumor imaging with good biocompatibility, indicating huge application potential.

HY-W324458

MCA succinimidyl ester	Fluorescent Dyes/Probes
MCA succinimidyl ester is a derivative of MCA (HY-W027544). MCA succinimidyl ester has succinimidyl ester can react selectively with amines. MCA succinimidyl ester can be used as peptide substrate for fluorescence resonance energy transfer.

HY-134566

NBD-X, SE
Fluorescent Dyes/Probes

NBD-X, SE, the acceptor fluorophore, can be used to create environment sensitive bioconjugates.
HY-101891

Di-8-ANEPPS
Fluorescent Dyes/Probes

Di-8-ANEPPS is a naphthylstyryl voltage-sensitive dye, shifting both their fluorescence excitation and emission spectra upon changes in V_m .

HY-D0716

Fluo-3AM Fluo-3-pentaacetoxymethyl ester	Fluorescent Dyes/Probes
Fluo-3AM(Fluo-3-pentaacetoxymethyl ester) is a calcium indicator that exhibit an increase in fluorescence upon binding Ca2+; used to image the spatial dynamics of Ca2+ signaling, in flow cytometry experiments involving photoactivation of caged chelators, second messengers, and neurotransmitters, and for cell-based pharmacological screening.

HY-D0853A

DiAzKs hydrochloride H-L-Photo-lysine hydrochloride	Fluorescent Dyes/Probes
DiAzKs (H-L-Photo-lysine) hydrochloride is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs hydrochloride can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs hydrochloride acts as a UV light-activated photo-crosslinking probe.

HY-118320

Alizarine Yellow R Mordant orange 1	Fluorescent Dyes/Probes
Alizarine Yellow R (Mordant orange 1), a salicylic acid derivative, is a azo dye. Alizarine Yellow R is mostly used as a pH indicator, as a biological stain in chemical examinations and also in dyeing industries.

HY-B0883

Proflavine hemisulfate Proflavin hemisulfate; 3,6-Diaminoacridine hemisulfate	Fluorescent Dyes/Probes
Proflavine hemisulfate, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent. Proflavine hemisulfate behaves as a pore blocker for K_ir3.2. Proflavine hemisulfate is a potential lead compound for K_ir3.2-associated neurological diseases.

HY-151710

Sulfo-Cy3 Azide	Fluorescent Dyes/Probes
Sulfo-Cy3 Azide is a water-soluble fluorogenic dye containing an azide group, which enables Click Chemistry. Sulfo-Cy3 Azide can be used for the labeling of sensitive molecules such as proteins.

HY-B1025

Digoxigenin Lanadigenin	Fluorescent Dyes/Probes
Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes.

HY-W040291

7-Hydroxy-4-methylcoumarin-3-acetic acid, SE	Fluorescent Dyes/Probes
7-Hydroxy-4-methylcoumarin-3-acetic acid, SE is a fluorophore that can be used for labeling peptides at the N-terminal.

HY-D1712

Phalloidin-Biotin
Fluorescent Dyes/Probes

Phalloidin-Biotin is a biotinized Phalloidin (HY-P0028). Phalloidin-Biotin can be used to label F-actin.
HY-D1346

610CP
Fluorescent Dyes/Probes

610CP, a carbopyronine derivative, could be used to label actin filaments. The absorption λ_max and fluor λ_max values are 609 nM and 634 nM, respectively.

HY-D0073

2,3-Diaminonaphthalene	Fluorescent Dyes/Probes
2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium detection and also used for the fluorometric determination of nitrite.

HY-D1081

6-DTAF hydrochloride
Fluorescent Dyes/Probes

6-DTAF hydrochloride is a fluorescein that can be used to label peptides and nucleotides.

HY-151690

FAM hydrazide, 6-isomer	Fluorescent Dyes/Probes
FAM hydrazide, 6-isomer is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer can be used for the labeling of carbonyl compounds, aldehydes, and ketones.

HY-W320397

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan	Fluorescent Dyes/Probes
4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.

HY-151712

Sulfo-Cy5-Methyltetrazine	Fluorescent Dyes/Probes
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

HY-D0921

Heptamethine cyanine dye-1
ADS 815EI
Fluorescent Dyes/Probes

Heptamethine cyanine dye-1 is a near-infrared cyanine dye for fluorescence imaging in biological systems.

HY-D0167

NHS-5(6)Carboxyrhodamine	Fluorescent Dyes/Probes
NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions.

HY-130013

HKYellow-AM (6/12-mixture)	Fluorescent Dyes/Probes
HKYellow-AM (6/12-mixture) is a fluorogenic probe extracted from patent EP2809666B1, compound 14, which can be used for sensitive and specific detection of peroxynitrite.

HY-D1461

Fluorescein Di-β-D-Glucopyranoside	Fluorescent Dyes/Probes
Fluorescein Di-β-D-Glucopyranoside is a specific β-glucocerebrosidase substrate that can be used for the intralysosomal β-galactosidase.

HY-101901

Oxazine 1 perchlorate
Fluorescent Dyes/Probes

Oxazine 1 perchlorate is a symmetric cationic dye (λ_ex=653 nm, λ_em=666 nm).

HY-D1262

BODIPY-TS Thiol-green 2	Fluorescent Dyes/Probes
BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reaction to thiols. Ex: 490 nM; Em: 515 nM.

HY-D1463

Nile Blue Methacrylamide	Fluorescent Dyes/Probes
Nile Blue Methacrylamide is a Nile Blue-based nanosized pH densor that can be used for simultaneous far-red and near-infrared live bioimaging.

HY-111263

NIAD-4	Fluorescent Dyes/Probes
NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (K_i) of 10 nM.

HY-D1653

BDP 581/591 NHS ester

Fluorescent Dyes/Probes

BDP 581/591 NHS ester is a a borondipyrromethene dye (Ex=585 nm, Em=594 nm) that has relatively long fluorescence lifetime and two photon excitation cross section. BDP 581/591 NHS ester can be used for fluorescence polarization analysis and also reacts with reactive oxygen species (ROS) and alter fluorescence. BDP 581/591 NHS ester is also an NHS ester derivative that can be used to bind primary and secondary amine groups of proteins, peptides and other molecules.

HY-D1544

Uniblue A sodium
Fluorescent Dyes/Probes

Uniblue A sodium is a reactive protein stain that can be used in the covalent pre-gel staining of the protein (Ex=594 nM).

HY-D1571

CellTracker Blue CMF2HC Dye	Fluorescent Dyes/Probes
CellTracker Blue CMF2HC Dye is a blue dye, can be used in two-channel nuclei acid sequencing, with blue and purple excitation light (450-460 nm/400-405nm or 415-450 nm/480-525nm). CellTracker Blue CMF2HC Dye can be used to rapid determination of antibiotic sensitivity of microorganisms.

HY-W127703

Octadecyl Rhodamine B chloride	Fluorescent Dyes/Probes
Octadecyl Rhodamine B chloride is a cationic amphiphile that can be used for staining cell membranes. Octadecyl Rhodamine B chloride can be used in numerous studies including electronic energy transfer in organized molecular assemblies, membrane structure, and distances of closest approach between protein domains and membranes.

HY-114491

Rineterkib

Fluorescent Dyes/Probes

Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF.

HY-D1049

DNP-X acid 6-((2,4-Dinitrophenyl)amino)hexanoic acid	Fluorescent Dyes/Probes
DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid), an amine-reactive building block for developing a probe, can be recognized by anti-DNP antibodies. DNP-X acid is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.

HY-D1684

DCDAPH	Fluorescent Dyes/Probes
DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid (Aβ) plaques (λ_ex/λ_em=597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates (K_i=37 nM, K_d=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo.

HY-66020

6-FITC
6-Fluorescein Isothiocyanate
Fluorescent Dyes/Probes

6-FITC (6-Fluorescein Isothiocyanate) is a derivative of fluorescein used in wide-ranging applications including flow cytometry.
HY-D0032

DAF-2DA
5,6-Diaminofluorescein diacetat
Fluorescent Dyes/Probes

DAF-2DA (5,6-Diaminofluorescein diacetat) is most widely probe for NO measurement.
HY-D1587

8-Phenyl-2,6-diethyl-BODIPY 505/515
Fluorescent Dyes/Probes

8-Phenyl-2,6-diethyl-BODIPY 505/515 is a derivative of BODIPY 505/515 (Ex=525 nm，Em=544 nm).

HY-D1546

Biotin-C2-maleimide	Fluorescent Dyes/Probes
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule.

HY-D0022

5-Aminofluorescein 5-AF	Fluorescent Dyes/Probes
5-Aminofluorescein (5-AF) is a fluorescence marker, covalently bound to human serum albumin. The excitation wavelength is 490 nm and the emission wavelength is 515 nm.

HY-101902

Quin-2AM
Quin-2 acetoxymethyl ester
Fluorescent Dyes/Probes

Quin-2AM is a fluorecent Ca²⁺ chelator, with high affinity for calcium.

HY-W248115

Pyrromethene 597	Fluorescent Dyes/Probes
Pyrromethene 597 is a BODIPY laser dye. Pyrromethene 597 displays wide tuning range of lasing wavelengths and high photostability. Pyrromethene 597 can be used as a thermal probe.

HY-101896

Fluo-4 AM
Fluorescent Dyes/Probes

Fluo-4 AM is a cell-permeable Ca²⁺ indicator.

HY-D0819A

CY5-SE triethylamine salt Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt	Fluorescent Dyes/Probes
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm).

HY-15935C

X-Gluc sodium	Fluorescent Dyes/Probes
X-Gluc sodium is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system).

HY-D0824

CY7-SE Sulfo-Cyanine7 Succinimidyl Ester	Fluorescent Dyes/Probes
CY7-SE (Sulfo-Cyanine7 Succinimidyl Ester) is a fluorescence labeling agent (Ex=700-770 nm, Em=790 nm). Cyanine dyes are used to label proteins, antibodies, peptides, and oligonucleotides.

HY-D1418

CP-BP-SFAC
Fluorescent Dyes/Probes

CP-BP-SFAC is a luminogenic molecule. CP-BP-SFAC exhibits strong sky-blue delayed fluorescence in neat films.

HY-D1654

BDP 581/591 maleimide	Fluorescent Dyes/Probes
BDP 581/591 maleimide is a linker of the BDP 581/591 dye. It has a long fluorescence lifetime and can be used for fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5, for the labeling of sulfhydryl groups of proteins and peptides.

HY-D0112

7-Hydroxycoumarin-4-acetic acid	Fluorescent Dyes/Probes
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λ_max=326 nm).

HY-D0569

Disperse Blue 148
C.I. Disperse Blue 148; C.I. 11124
Fluorescent Dyes/Probes

Disperse Blue 148 is the best high-temperature trichromatic blue azo dye.

HY-D0893

NSP-SA-NHS	Fluorescent Dyes/Probes
NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A with NSP-SA-NHS-labeled has been developed.

HY-D1261

Naph-EA-mal Thiol-green 1	Fluorescent Dyes/Probes
Naph-EA-mal (Thiol-green 1) is a rapid detect and ultrafast turn-on thiol fluorescence probe for protein labeling and bioimaging. Naph-EA-mal (Thiol-green 1) can be used to detect thiols in living cells, label the protein thiols, quantify the concentration of total thiols in cell lysate, and determine the reversible protein thiols oxidation in fixed cells. Ex: 488 nM; Em: 540 nM.

HY-118159

Diphenyl-1-pyrenylphosphine DPPP	Fluorescent Dyes/Probes
Diphenyl-1-pyrenylphosphine (DPPP) is a fluoregenic peroxide reactive probe. Diphenyl-1-pyrenylphosphine exhibits a unique phototriggered aggregation-induced emission (AIE)/aggregation-induced quenching (ACQ) transition with a remarkable third-order nonlinear optical signal change.

HY-D0026

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester	Fluorescent Dyes/Probes
7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester is a bioReagent, suitable for fluorescence, can be used for amine-reactive labeling.

HY-W008292

Carbostyril 124
Fluorescent Dyes/Probes

Carbostyril 124 is a sensitising chromophore. Carbostyril 124 is a reasonably effective organic sensitizer for a proximate bound terbium ion.

HY-D1251

TRFS-red	Fluorescent Dyes/Probes
TRFS-red, a red fluorescence emission off-on probe, is selective for thioredoxin reductase (TrxR). TRFS-red exhibits high response rate and sensitivity. TRFS-red can be used for imaging live cells.

HY-D1268

Seph-PAO
Fluorescent Dyes/Probes

Seph-PAO is the modified PAO attached a sepharose fluorophore and is used to detect the thioredoxin reductase (TrxR).
HY-P1005

Ac-DEVD-AFC
Fluorescent Dyes/Probes

Ac-DEVD-AFC is a fluorogenic substrate (λ_ex=400 nm, λ_em=530 nm).

HY-151662

4-Azido-2,3,5,6-tetrafluorobenzoic Acid N3-TFBA	Fluorescent Dyes/Probes
4-Azido-2,3,5,6-tetrafluorobenzoic Acid (N3-TFBA) is a click chemistry reagent containing an azide group. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid is a complex with FAM-labeled DNA probe. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid can be used as versatile photoaffinity labeling agents to probe biological receptors.

HY-151615

DCI-Br-3	Fluorescent Dyes/Probes
DCI-Br-3 is a rapid, highly sensitive, and selective probe to monitor thiols in the epileptic brain. (λ_ex=537 nm, λ_em=675 nm).DCI-Br-3 can effectively cross the blood-brain barrier (BBB).

HY-121608

Lumiflavin
Lumiflavine
Fluorescent Dyes/Probes

Lumiflavin (Lumiflavine), a riboflavine analog, can be used to detect riboflavine uptake.

HY-D1362

BDP 630/650 maleimide	Fluorescent Dyes/Probes
BDP 630/650 maleimide is a fluorophore which can be read on the Cyanine5 channel. BDP 630/650 maleimide is useful for fluorescence lifetime related measurements because of the long life time of the excited state.

HY-D0141

12-(1-Pyrenyl)dodecanoic acid
Fluorescent Dyes/Probes

12-(1-Pyrenyl)dodecanoic acid is a fluorescence probe.

HY-D1657

BDP 581/591 azide	Fluorescent Dyes/Probes
BDP 581/591 azide is an azide derivative of BDP 581/591. BDP 581/591 is a universal, photostable fluorophore. BDP 581/591 azide can be used for the conjugation with both small molecules and biomolecules to construct tracers for fluorescence polarization assays and microscopy probes.

HY-D1054

Cy2 (iodine) Cyanine2 (iodine)	Fluorescent Dyes/Probes
Cy2 is a cyanine dye used for labeling amino-groups in peptides, proteins, and oligonucleotides, with λ excitation of 488 nm and λ emission of 520 nm.

HY-D1601

N-Aminofluorescein	Fluorescent Dyes/Probes
N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu²⁺. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu²⁺ in biological systems with λex/em=495/516 nm.

HY-P1002

Suc-Leu-Leu-Val-Tyr-AMC
Fluorescent Dyes/Probes

Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate.

HY-D0819

CY5-SE

Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester

Fluorescent Dyes/Probes

Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.

HY-U00452

PL553
Fluorescent Dyes/Probes

PL553 is a specific and high-affinity fluorigenic substrate of Leukotriene A4 hydrolase, with a λ_max of 210 nm and λ_em of 410 nm.

HY-D1666

BDP 558/568 azide	Fluorescent Dyes/Probes
BDP 558/568 azide is an azide modified BDP 558/568 (BDP 558/568: Ex=558 nm, Em=568 nm). BDP 558/568 azide can be used in the labeling of click chemistry.

HY-D1168

Oil Red O	Fluorescent Dyes/Probes
Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses.

HY-D0940

H2DCFDA DCFH-DA; 2',7'-Dichlorodihydrofluorescein diacetate	Fluorescent Dyes/Probes
H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm).

HY-W010947

4-Methylumbelliferyl palmitate

Fluorescent Dyes/Probes

4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions.

HY-W179417

Methacrolein-2,4-dinitrophenylhydrazone
Fluorescent Dyes/Probes

Methacrolein-2,4-dinitrophenylhydrazone is a small molecule azo and nitro dye.

HY-D0259

Erythrosine B Erythrosin extra bluish	Fluorescent Dyes/Probes
Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models.

HY-D1353

LipidGreen 2	Fluorescent Dyes/Probes
LipidGreen 2 is a second generation small molecule probe for lipid imaging. LipidGreen 2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish.

HY-D1641

5,5'-Dimethyl BAPTA tetrapotassium	Fluorescent Dyes/Probes
5,5'-Dimethyl BAPTA tetrapotassium is a water-soluble, extracellular membrane metal chelator with relative selectivity for calcium ions.

HY-D1082

5-DTAF	Fluorescent Dyes/Probes
5-DTAF is a isomeric fluorescein derivative that directly react with polysaccharides and other alcohols in aqueous solution at pH ＞ 9. The maximum of the 5-DTAF emission profile is at a wavelength of 518 nm after excitation at 488 nm.

HY-111330

Hydroxyphenyl Fluorescein HPF	Fluorescent Dyes/Probes
Hydroxyphenyl fluorescein (HPF) is the reagent that can directly detect highly reactive oxygen species (hROS). Hydroxyphenyl fluorescein selectively and dose-dependently reacts with hROS, such as the hydroxyl radical and peroxynitrite, which exhibit strong fluorescence.

HY-P1004

Luciferase	Fluorescent Dyes/Probes
Luciferase from Vibrio fischeri has also been used in a study to investigate the sensitivity of dark mutants of various strains of luminescent bacteria to reactive oxygen species.

HY-D1708

RuBP-4S
Fluorescent Dyes/Probes

RuBP-4S is a luminescent ruthenium complex.

HY-18743

Coelenterazine

Fluorescent Dyes/Probes

Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite.

HY-15941

5(6)-FITC Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers	Fluorescent Dyes/Probes
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of fluorescein dye that has wide-ranging applications as a label for antibodies and other probes, for use in fluorescence microscopy, flow cytometry and immunofluorescence-based assays such as Western blotting and ELISA.

HY-133522

HBC525	Fluorescent Dyes/Probes
HBC525 is a HBC-like fluorophore and a fluorogenic RNA aptamer (K_d=3.8 nM). HBC525 can be directly used as fusion tags for the imaging and tracking of cellular RNAs of interest. Fluorogenic RNA aptamers have also been used to construct various interesting dynamic RNA nanodevices for cellular target detection and imaging.

HY-D1664

BDP 558/568 alkyne	Fluorescent Dyes/Probes
BDP 558/568 alkyne is a borondipyrromethene dye. BDP 558/568 alkyne possesses high quantum yield. BDP 558/568 alkyne is a terminal alkyne for copper-catalyzed Click chemistry. (λ_ex=558 nm, λ_em=568 nm).

HY-W337201

5-Bromo-4-chloro-3-indolyl β-D-cellobioside
Fluorescent Dyes/Probes

5-Bromo-4-chloro-3-indolyl β-D-cellobioside is a chromogenic compound used to detect cellobiohydrolases.

HY-D0233

Leucocrystal violet	Fluorescent Dyes/Probes
Leucocrystal violet is a triphenylmethane dye which can be used to detect antimony in environmental and biological samples using spectrophotometric techniques.

HY-D0047

5-CFDA 5-Carboxyfluorescein diacetate	Fluorescent Dyes/Probes
5-CFDA(5-Carboxyfluorescein diacetate) is membrane-permeant and can be loaded into cells via incubation; hydrolyzed by intracellular esterases to 5-carboxyfluorescein; used for labeling human intervertebral disk cells in vitro for fluorescence microscopy.

HY-P3484

Dnp-PLGLWA-DArg-NH2 TFA	Fluorescent Dyes/Probes
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm).

HY-D1557

Cyanine5.5 tetrazine	Fluorescent Dyes/Probes
Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications.

HY-114958

RH 421
Fluorescent Dyes/Probes

RH 421 is a voltage-sensitive styryl dye that can penetrate through the lipid bilayers. RH 421 is a chromogenic substrate for β-galactosidase.

HY-D1426

Di-12-ANEPPQ	Fluorescent Dyes/Probes
Di-12-ANEPPQ is a fast-responding membrane potential dye. Di-12-ANEPPQ, the lipophilic dye, shows cell-specific loading and Golgi-like staining patterns with minimal background fluorescence in the slices of neocortex and hippocampus.

HY-D1626

DiSC18(3)
3,3'-Dioctadecylthiacarbocyanine perchlorate
Fluorescent Dyes/Probes

DiSC18(3) is a lipophilic carbocyanine dye for membrane labelling.

HY-N2306

Aclacinomycin A Aclarubicin	Fluorescent Dyes/Probes
Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis.

HY-D0150

Thiazole Orange	Fluorescent Dyes/Probes
Thiazole orange is an unsymmetrical cyanine dye which can be conjugated to oligonucleotides (ONs) to create fluorogenic hybridisation probes. Thiazole orange can be used for reticulocyte analysis.

HY-151711

Sulfo-Cy5.5 Azide	Fluorescent Dyes/Probes
Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides.

HY-D1705

Ac-ANW-AMC
Fluorescent Dyes/Probes

Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm).

HY-D1661

BDP 564/570 NHS ester	Fluorescent Dyes/Probes
BDP 564/570 NHS ester is a lypophilic orange fluorescein dye, can be used for the labeling of amine containing biomolecules, including amine-modified oligonucleotides.

HY-116583

Resorufin butyrate
Fluorescent Dyes/Probes

Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm).

HY-D1427

Di-2-ANEPEQ	Fluorescent Dyes/Probes
Di-2-ANEPEQ is a voltage sensitive membrane potential fluorescence dye. Di-2-ANEPEQ can be used for the evaluation of voltage-sensitive fluorescence dyes for monitoring neuronal activity in the embryonic central nervous system.

HY-D1042

1,4-Dichloro 5-carboxytetramethylrhodamine
Fluorescent Dyes/Probes

1,4-Dichloro 5-carboxytetramethylrhodamine is a fluorescence labeling agent (Ex=541 nm, Em=568 nm).
HY-D0801

Calmagite
Fluorescent Dyes/Probes

Calmagite is a complexometric indicator which can be used to detect calcium and magnesium in various samples.

HY-D1525

N-(7-Nitrobenzofurazan-4-yl)phallacidin	Fluorescent Dyes/Probes
N-(7-Nitrobenzofurazan-4-yl)phallacidin is a fluorochrome. N-(7-Nitrobenzofurazan-4-yl)phallacidin can be used visualizing probe for actin.

HY-W020030

4-Amino-3,6-disulfonaphthalic anhydride dipotassium
Fluorescent Dyes/Probes

4-Amino-3,6-disulfonaphthalic anhydride dipotassium is a Lucifer dye.

HY-D1658

BDP 581/591 amine hydrochloride	Fluorescent Dyes/Probes
BDP 581/591 amine hydrochloride is a BODIPY dye linker. BDP 581/591 is a universal, photostable fluorophore. The addition of the amine group allows for the compound to react with carboxylic acids, activated NHS esters and other carbonyl groups.

HY-D1665

BDP 558/568 amine	Fluorescent Dyes/Probes
BDP 558/568 amine is an amine derivative of BDP 558/568. BDP 558/568 is a borondipyrromethene dye with yellow/orange emission. BDP 558/568 amine can be conjugated by means of reactions with various electrophiles.

HY-D0027

7-Amino-4-methylcoumarin
Coumarin 120; AMC
Fluorescent Dyes/Probes

7-amino-4-methylcoumarin (Coumarin 120) has been used as a fluorogenic probe for many serine proteases.

HY-151750

Pyrene phosphoramidite dU	Fluorescent Dyes/Probes
Pyrene phosphoramidite Du is a click chemistry reagent containing pyrene groups. The pyrene group in Pyrene phosphoramidite Du can be inserted into DNA with strong blue fluorescence.

HY-D1091

DiSBAC2(3)
Fluorescent Dyes/Probes

DiSBAC2(3) is an anionic membrane-potential-sensitive dye. DiSBAC2(3) is a plasma membrane potential indicator.

HY-137103

BTC-AM	Fluorescent Dyes/Probes
BTC-AM is a low affinity calcium indicator. BTC-AM has substantial calcium-independent fluorescence at all excitation wavelengths. BTC-AM is readily loaded into neurons and is rapidly hydrolysed.

HY-D1045

Dabcyl acid
DABCYL; Para-methyl red
Fluorescent Dyes/Probes

Dabcyl acid (Dabcyl) is the original dark fluorescence quencher.
HY-103594

2-Aminoacridone
Fluorescent Dyes/Probes

2-Aminoacridone is a widely used fluorophore (λ_exc=428 nm, λ_em=525 nm).

HY-D0214

Rose Bengal sodium	Fluorescent Dyes/Probes
Rose Bengal sodium, a synthetic fluorescein derivative, and is a crimson-coloured dye with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, and can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities.

HY-D1672

TMR Biocytin	Fluorescent Dyes/Probes
TMR Biocytin is a polar tracer used in the research of cell-cell and cell-liposome fusions, as well as membrane permeability and cellular uptake during pinocytosis. TMR Biocytin can be detected using streptavidin, and is an effective neuronal tracer in live tissue (Ex=544 nm, Em=571 nm).

HY-D1624

3,3'-Diheptylthiacarbocyanine iodide
Fluorescent Dyes/Probes

3,3′-Diheptylthiacarbocyanine iodide is a cyanine dye for measuring membrane potential. (λ_ex=562 nm, λ_em=575 nm).

HY-122878

HS-131	Fluorescent Dyes/Probes
HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers.

HY-15922

Luminol Diogenes reagent	Fluorescent Dyes/Probes
Luminol is a chemical that exhibits chemiluminescence with pK_a values of 6.74 and 15.1. Luminol exhibits chemiluminescence (CL) at 425 nm λ_max. Luminol is commonly used in forensics as a diagnostic tool for the detection of blood stains.

HY-D0147

Resorufin pentyl ether Pentoxyresorufin	Fluorescent Dyes/Probes
Resorufin pentyl ether (Pentoxyresorufin) is a Resazurin (HY-111391) analogue. Resorufin pentyl ether can function as a substrate probe to characterize and differentiate between a variety of inducers of cytochromes P-450. Resorufin pentyl ether has bactericidal activity against N. gonorrhoeae.

HY-P1004A

Luciferase, firefly
Fluorescent Dyes/Probes

Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles.

HY-D0084

3,3'-Dihexyloxacarbocyanine iodide DiOC6(3) iodide	Fluorescent Dyes/Probes
3,3'-Dihexyloxacarbocyanine iodide is a carbocyanine dye which can be used to monitor changes in mitochondrial membrane potential.

HY-D1560

FG 488 DHPE	Fluorescent Dyes/Probes
FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm. FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well.

HY-P2536

Mca-Ala-Pro-Lys(Dnp)-OH	Fluorescent Dyes/Probes
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung.

HY-66019

FITC Fluorescein 5-isothiocyanate	Fluorescent Dyes/Probes
FITC (Fluorescein 5-isothiocyanate) is a fluorescence probe for the labeling of amines. FITC is a pH- and Cu²⁺-sensitive fluorescence dye.

HY-114907

4',5'-Dibromofluorescein Eosinic acid; Solvent Red 72	Fluorescent Dyes/Probes
4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis.

HY-D0817

Rhodamine 110 Rhodamine 110 chloride; RH110	Fluorescent Dyes/Probes
Rhodamine 110 is a sensitive and selective substrate for assaying proteinases in solution or inside living cells. The excitation wavelength is 498 nm and the emission wavelength is 521 nm.

HY-D1073

DiOC7(3) 3,3'-Diheptyloxacarbocyanine iodide	Fluorescent Dyes/Probes
DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities.

HY-147170

(1,1'-Dipyrenyl)dimethyl ether	Fluorescent Dyes/Probes
(1,1'-Dipyrenyl)dimethyl ether exhibits intramolecular excimer fluorescence in competition with fluorescence from the locally excited pyrene chromophore. (1,1'-Dipyrenyl)dimethyl ether is soluble in synthetic phospholipid membranes.

HY-D1429

ER-Tracker Blue-White DPX	Fluorescent Dyes/Probes
ER-Tracker Blue-White DPX is a photostable probe used to selectively label the endoplasmic reticulum for fluorescence microscopy imaging.

HY-D0309

Rhodamine 6G Basic Red 1	Fluorescent Dyes/Probes
Rhodamine 6G is a rhodamine analog useful in Pgp efflux assays. It can be used in characterizing the kinetics of MRP1- mediated efflux, and as a laser dye and potential mitochondrial probe.

HY-W324406

1,2-Diamino-3,4-ethylenedioxybenzene
Fluorescent Dyes/Probes

1,2-Diamino-3,4-ethylenedioxybenzene is a carbonyl-reactive fluorometric labeling agent.

HY-D1046

Dabcyl acid, SE Dabcyl, SE	Fluorescent Dyes/Probes
Dabcyl acid, SE is the amino-reactive form of Dabcyl acid (DABCYL), and widely used to prepare a variety of FRET-based probes that contain DABCYL.

HY-D0853

DiAzKs H-L-Photo-lysine	Fluorescent Dyes/Probes
DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe.

HY-D1252

Fast-TRFS
Fluorescent Dyes/Probes

Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells.

HY-151774

TAMRA hydrazide (6-isomer)	Fluorescent Dyes/Probes
TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes.

HY-D0071

N-4-(5,6-Dimethoxy-N-phthalimidinyl)phenylmaleimide
Fluorescent Dyes/Probes

N-4-(5,6-Dimethoxy-N-phthalimidinyl)phenylmaleimide is a fluorescence reagent for labeling thiol.

HY-D1530

4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide	Fluorescent Dyes/Probes
4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide is a fluorogenic substrate for detecting α-N-acetylglucosaminidase.

HY-D0824A

CY7-SE triethylamine Sulfo-Cyanine7 Succinimidyl Ester triethylamine	Fluorescent Dyes/Probes
CY7-SE triethylamine (Sulfo-Cyanine7 Succinimidyl Ester triethylamine) is a fluorescence labeling agent (Ex=700-770 nm, Em=790 nm). Cyanine dyes are used to label proteins, antibodies, peptides, and oligonucleotides.

HY-W345148

2-Naphthylamine-6,8-disulfonic acid potassium	Dyes Fluorescent Dyes/Probes
2-Naphthylamine-6,8-disulfonic acid potassium is chemical that can be used for preparing dyestuff, medicine, agricultural chemicals etc.

HY-W354821

4-Methylumbelliferyl Decanoate 4-MUD	Chromogenic Substrates Fluorescent Dyes/Probes
4-Methyl-2-oxo-2H-1-benzopyran-7-yl decanoate is a fluorogenic substrate used to follow the hydrolytic activity of carboxylesterases.

HY-W357142

3-Acetylumbelliferyl β-D-Glucopyranoside	Chromogenic Substrates Fluorescent Dyes/Probes
3-Acetylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase and can be used as a positive control substrates for β-D-glucosidase.

Cat. No.	Product Name	Type

HY-143702

Fluorescent DOTAP
LNPs for Drug Delivery

Fluorescent DOTAP, a cationic lipid, can be used for the research of nucleic acid and protein delivery.
HY-D1021

AA-dUTP sodium salt
Aminoallyl-dUTP sodium salt
Biochemical Assay Reagents

AA-dUTP sodium salt is a fluorescent dye which can be used to stain cDNA.
HY-139101

Guanosine 5'-triphosphate-5'-adenosine
GpppA
Gene Sequencing and Synthesis

Guanosine 5'-triphosphate-5'-adenosine, the 5′ cap analog, is a fluorescent substrate analog.

HY-126944

2-Aminobenzanilide 2-Amino-N-phenylbenzamide	Biochemical Assay Reagents
2-Aminobenzamide is a neutral and stable compound used as fluorescent tag, numerously in Glycan analysis. 2-aminobenzamide acts as the starting material for several important reactions like Bargellini reaction as an competent ambident nucleophile. Specifically 2-aminobenzamide and its derivatives are used in the blood coagulation cascade.

Cat. No.	Product Name	Target	Research Area

HY-P2528

*Enhanced Green Fluorescent* Protein (EGFP) (200-208)**	Peptides	Others
Enhanced Green Fluorescent Protein (EGFP) (200-208) is a marker gene product derived from the jellyfish Aequorea Victoria. Enhanced Green Fluorescent Protein (EGFP) (200-208) is a common reporter protein and is easy to detect.

HY-P3474

Mca-PLGL-Dpa-AR-NH2
MMP Cancer

Mca-PLGL-Dpa-AR-NH2 is a fluorescent peptide MMP substrate.
HY-P2065

Ac-VEID-AMC
Peptides Others

Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm).
HY-P3791

N-Succinyl-Ile-Ile-Trp-AMC
Peptides Others

N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY).

HY-P2550

β-Amyloid (1-40), FAM-labeled	Amyloid-β Peptides	Neurological Disease
β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λ_ex= 492 nm and λ_em= 518 nm).

HY-D1532

DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS	Peptides Parasite	Others
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite.

HY-P2615

Ac-VDVAD-AFC	Peptides	Cancer
Ac-VDVAD-AFC is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer.

HY-P3475

Mca-VDQMDGW-K(Dnp)-NH2
Peptides Others

Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity.
HY-P1003

Ac-DEVD-AMC
Caspase Cancer

Ac-DEVD-AMC is the Caspase-3 fluorescent substrate.

HY-P3749

Mca-(ala7,lys(dnp)9)-bradykinin	Peptides	Others
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage.

HY-P1459

Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)	Bacterial	Infection
Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.

HY-P1853

Abz-FR-K(Dnp)-P-OH	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Abz-FR-K(Dnp)-P-OH is an angiotensin I-converting enzyme (ACE) substrate and an internally quenched fluorogenic substrate for real time fluorescent assay.

HY-P2267

LDV
Integrin Others

LDV, a tripeptide, is a non-fluorescent analog of LDV-FITC. LDV is a α4β1 integrin (VLA-4) ligand, and binds α4β1 integrin in leukemia cells.

HY-P3432

DfTat	Peptides	Others
DfTat is a fluorescently labeled dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection.

HY-P3110

Ac-DNLD-AMC	Peptides	Others
Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity.

HY-P1883

Bacterial Sortase Substrate III, Abz/DNP	Peptides	Infection
Bacterial Sortase Substrate III, Abz/DNP is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.

HY-P1883A

Bacterial Sortase Substrate III, Abz/DNP TFA	Peptides	Infection
Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.

HY-P3362

Ac-IETD-AMC
Peptides Others

Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity.

HY-P1986

Z-DEVD-AFC	Caspase	Cancer
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity.

HY-P2208

Z-IETD-AFC
Peptides Cancer

Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity.

HY-111956B

D-Ala-Lys-AMCA hydrochloride	Peptides	Cancer
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis.

HY-P1169

Ac-IETD-AFC
Caspase Others

Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B.
HY-136865

MeOSuc-AAPV-AMC
Peptides Others

MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (K_m: 362 μM, Ex=380 nm, Em=460 nm).

HY-P2270

Phalloidin-TRITC	Arp2/3 Complex	Others
Phalloidin-TRITC is a TRITC labeled, red fluorescence probe for F-actin. Phalloidin, bound to actin filaments, reacts covalently with amino acids Glu-llT, Met-ll9, and Met355, which are very close to the nucleotide binding site.

HY-P1005

Ac-DEVD-AFC
Peptides Cancer

Ac-DEVD-AFC is a fluorogenic substrate (λ_ex=400 nm, λ_em=530 nm).
HY-P1002

Suc-Leu-Leu-Val-Tyr-AMC
Peptides Others

Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic substrate.

HY-P1004

Luciferase	Reactive Oxygen Species	Cancer
Luciferase from Vibrio fischeri has also been used in a study to investigate the sensitivity of dark mutants of various strains of luminescent bacteria to reactive oxygen species.

HY-P3484

Dnp-PLGLWA-DArg-NH2 TFA	MMP	Cancer
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm).

HY-P1004A

Luciferase, firefly
Peptides Others

Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles.

HY-P2536

Mca-Ala-Pro-Lys(Dnp)-OH	Angiotensin-converting Enzyme (ACE)	Others
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung.

Cat. No.	Product Name

HY-K1042

AntiFade Mounting Medium
MCE AntiFade Mounting Medium can slow the fluorescence quenching of various common fluorescent dyes with simple operation and good anti-fluorescence quenching effect.

HY-K0901

AMCA Phalloidin

AMCA Phalloidin is Phalloidin conjugated to the fluorescent dye AMCA. Phalloidin binds F-actins with high selectivity while AMCA provides stable and bright blue fluorescence.

HY-K0902

Fluorescein Phalloidin
Fluorescein Phalloidin is Phalloidin conjugated to the fluorescent dye Fluorescein. Phalloidin binds F-actins with high selectivity while Fluorescein provides stable and bright green fluorescence.

HY-K0903

Rhodamine Phalloidin
Rhodamine Phalloidin is Phalloidin conjugated to the fluorescent dye Tetramethylrhodamine. Phalloidin binds F-actins with high selectivity while Rhodamine provides stable and bright orange fluorescence.

Cat. No.	Product Name	Target	Category

HY-N2893

Cepharanone B Aristolactam B II	Others	Alkaloids Indole Alkaloids Plants Menispermaceae Stephania cepharantha Hay. Classification of Application Fields Disease Research Fields Other Diseases
Cepharanone B is a fluorescent component isolated from the callus tissue of stephania cephaiuntha.

HY-76981

5-Hydroxy-1-tetralone	Others	Structural Classification Phenols Monophenols Ketones, Aldehydes, Acids Endogenous metabolite Classification of Application Fields Disease Research Fields Other Diseases
5-hydroxy-1-tetralone can be used as a fluorescent labeling reagent for the determination of glycosphingolipid from biological samples.

HY-W091541

4-Hydroxy-1H-indole-3-carbaldehyde 4-Hydroxyindole-3-carboxaldehyde	Others	Structural Classification Alkaloids Indole Alkaloids Phenols Monophenols Plants Capparidaceae Capparis spinosa L. Classification of Application Fields Disease Research Fields Other Diseases
4-Hydroxy-1H-indole-3-carbaldehyde is a plant metabolite found in Capparis spinosa L.. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe.

HY-N6716

Filipin complex	Fungal Antibiotic	Structural Classification Antibiotics Other Antibiotics Source Classification Microorganisms Other Diseases Disease Research Fields Classification of Application Fields
Filipin complex is a potent broad spectrum 28-membered ring pentaene macrolide antifungal antibiotic. Filipin complex is also a highly fluorescent polyene. Filipin complex specifically binds free cholesterol and is well established as a histochemical marker for the detection of unesterified cellular cholesterol. Filipin complex consists of four analogues (Filipins I-IV), with Filipin III (HY-N6718) comprising the bulk (>70%) of the complex.

HY-N7131

Coumarin 6	Others	Structural Classification Alkaloids Indole Alkaloids Plants Umbelliferae Ferula fukanensis K. M. Shen Classification of Application Fields Disease Research Fields Other Diseases
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems.

HY-Y1309

1-Naphthol Furro ER; NSC 9586; Nako TRB	Endogenous Metabolite	Structural Classification Phenols Monophenols Endogenous metabolite Classification of Application Fields Disease Research Fields Other Diseases
1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe.

HY-121271

Kadsurin	Others	Structural Classification Phenylpropanoids Lignans Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Classification of Application Fields Disease Research Fields Inflammation/Immunology
Kadsurin, a natural compound from the stems of Kadsura heteroclita (Schizandraceae), results in significant decreases of CCL₄- induced lipid-peroxidation products, such as thiobarbituric acid reactive substances (TBA-RS), conjugated dienes and fluorescent products in the liver of mice.

HY-N0188

Esculin	p38 MAPK	Structural Classification Phenylpropanoids Coumarins Phenols Monophenols Plants other families Classification of Application Fields Disease Research Fields Cancer
Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway.

HY-N2011

Octyl gallate n-Octyl gallate; Stabilizer GA 8	Bacterial HSV Influenza Virus Reactive Oxygen Species	Structural Classification Phenols Polyphenols Paeoniaceae Source Classification Paeonia lactiflora Pall. Plants Infection Disease Research Fields Classification of Application Fields
Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity. Octyl gallate (Progallin O) shows selective and sensitive fluorescent property. Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus.

HY-D0226

Quinizarin 1,4-Dihydroxyanthraquinone	DNA/RNA Synthesis Fungal	Structural Classification Quinones Anthraquinones Phenols Polyphenols Plants Solanaceae Rhizophora mucronata Lam Classification of Application Fields Disease Research Fields Infection
Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (K_d=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth.

HY-B1025

Digoxigenin Lanadigenin	Others	Structural Classification Steroids Scrophulariaceae Source Classification Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Inflammation/Immunology Disease Research Fields Classification of Application Fields
Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes.

HY-P1004

Luciferase	Reactive Oxygen Species	Structural Classification Natural Products Microorganisms Classification of Application Fields Disease Research Fields Cancer
Luciferase from Vibrio fischeri has also been used in a study to investigate the sensitivity of dark mutants of various strains of luminescent bacteria to reactive oxygen species.

HY-18743

Coelenterazine	Reactive Oxygen Species	Structural Classification Alkaloids Other Alkaloids Monophenols Phenols Polyphenols Source Classification Animals Disease Research Fields Cancer Classification of Application Fields
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite.

HY-N2306

Aclacinomycin A Aclarubicin	Topoisomerase DNA/RNA Synthesis Proteasome Antibiotic	Quinones Anthraquinones Structural Classification Microorganisms
Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis.

Cat. No.	Product Name	Species	Source

HY-P71461

GFP Protein, Aequorea victoria (His)
GFPGreen fluorescent protein
Mouse E. coli

Cat. No.	Product Name

HY-D0021S

Ethidium-d5 bromide
Ethidium-d5 bromide is the deuterium labeled Ethidium bromide. Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

HY-123533S

Resorufin-d6

Resorufin-d6 (NSC 12097-d6) is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte.

HY-111661S

6,7-Dimethyl-8-ribityllumazine-d6
6,7-Dimethyl-8-ribityllumazine-d6 is the deuterium labeled 6,7-Dimethyl-8-ribityllumazine. 6,7-Dimethyl-8-ribityllumazine is a direct biosynthetic precursor of Riboflavin (RBF; HY-B0456). 6,7-Dimethyl-8-ribityllumazine is a noncovalently bound fluorophore of Lumazine protein (LumP), which is a fluorescent accessory protein.

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