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Results for "

folic

" in MCE Product Catalog:

34

Inhibitors & Agonists

7

Natural
Products

12

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas
  • HY-16637A
    Folic acid sodium

    Vitamin B9 sodium; Vitamin M sodium

    Endogenous Metabolite DNA/RNA Synthesis Neurological Disease
    Folic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the treatment of megaloblastic and macrocytic anemias due to folic deficiency.
  • HY-16637
    Folic acid

    Vitamin B9; Vitamin M

    DNA/RNA Synthesis Endogenous Metabolite Cancer Neurological Disease
    Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the treatment of megaloblastic and macrocytic anemias due to folic deficiency.
  • HY-16637S
    Folic acid-d2

    Vitamin B9-d2; Vitamin M-d2

    DNA/RNA Synthesis Endogenous Metabolite Cancer
    Folic Acid-d2 is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
  • HY-16637S1
    Folic acid-d4

    Vitamin B9-d4; Vitamin M-d4

    DNA/RNA Synthesis Endogenous Metabolite Cancer
    Folic acid-d4 (Vitamin B9-d4) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
  • HY-132070
    FA-PEG5-Mal

    folic acid-PEG5-Mal

    PROTAC Linkers Cancer
    FA-PEG5-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • HY-14518
    Aminopterin

    4-Aminofolic acid; APGA

    Antifolate Cancer Inflammation/Immunology
    Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia.
  • HY-16637S2
    (Rac)-Folic acid-13C5,15N

    (Rac)-Vitamin B9-13C5,15N; (Rac)-Vitamin M-13C5,15N

    DNA/RNA Synthesis Endogenous Metabolite Cancer
    Folic acid-13C5,15N is the 13C-labeled and 15N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
  • HY-B0946
    Sulfamonomethoxine

    Bacterial Antibiotic Infection
    Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
  • HY-B0946S
    Sulfamonomethoxine-d4

    Bacterial Infection
    Sulfamonomethoxine-d4 is a deuterium labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
  • HY-113267
    Dihydrofolic acid

    Endogenous Metabolite Metabolic Disease
    Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid.
  • HY-129398
    Formiminoglutamic acid

    Endogenous Metabolite Metabolic Disease
    Formiminoglutamic acid, an endogenous metabolite, could be an index of folic-acid deficiency.
  • HY-108251
    Methotrexate metabolite

    DAMPA

    Antifolate Drug Metabolite Inflammation/Immunology
    Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent.
  • HY-113267S
    Dihydrofolic acid-d4

    Endogenous Metabolite Metabolic Disease
    Dihydrofolic acid-d4 is the deuterium labeled Dihydrofolic acid. Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid.
  • HY-17556
    Folinic acid

    leucovorin

    Antifolate Endogenous Metabolite Cancer
    Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity.
  • HY-18062
    Pyrimethamine

    Pirimecidan; Pirimetamin; RP 4753

    Antifolate Parasite Infection
    Pyrimethamine(RP4753) is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR).
  • HY-17556B
    Folinic acid calcium hydrate

    Leucovorin calcium hydrate

    Antifolate Endogenous Metabolite Cancer
    Folinic acid (Leucovorin) calcium hydrate is a biological folic acid and is generally administered along with Methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity.
  • HY-13664
    Folinic acid calcium

    Leucovorin calcium; Calcium folinate

    Antifolate Endogenous Metabolite Cancer
    Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity.
  • HY-14781
    Levomefolic acid

    5-MTHF

    Endogenous Metabolite Reactive Oxygen Species Cancer
    Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions.
  • HY-B0080
    Folinic acid calcium salt pentahydrate

    Leucovorin calcium salt pentahydrate

    Antifolate Cancer
    Folinic acid calcium salt pentahydrate (Leucovorin calcium salt pentahydrate) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity.
  • HY-B0946S1
    Sulfamonomethoxine-d3

    Bacterial Antibiotic Infection
    Sulfamonomethoxine-d3 is the deuterium labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
  • HY-114306
    EC0489

    Antifolate Cancer
    EC0489, a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor. Small molecule-drug conjugate (SMDC).
  • HY-18062S
    Pyrimethamine-d3

    Antifolate Parasite Infection
    Pyrimethamine-d3 (Pirimecidan-d3) is the deuterium labeled Pyrimethamine. Pyrimethamine is a medication used for protozoal infections; interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase (DHFR).
  • HY-B0946S2
    Sulfamonomethoxine-13C6

    Bacterial Antibiotic Infection
    Sulfamonomethoxine-13C6 is the 13C6 labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
  • HY-130569
    7-Hydroxymethotrexate

    Drug Metabolite Cancer Inflammation/Immunology
    7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
  • HY-133624
    1,1,3-Tribromoacetone

    Others Cancer
    1,1,3-Tribromoacetone is an impurity of Methotrexate (HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
  • HY-108251S
    Methotrexate metabolite-d3

    DAMPA-d3

    Antifolate Drug Metabolite Inflammation/Immunology
    Methotrexate metabolite-d3 (DAMPA-d3) is the deuterium labeled Methotrexate metabolite. Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent.
  • HY-113046
    5-Methyltetrahydrofolic acid

    5-Methyl THF

    Endogenous Metabolite Metabolic Disease
    5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.
  • HY-14519
    Methotrexate

    Amethopterin; CL14377; WR19039

    Antifolate DNA/RNA Synthesis ADC Cytotoxin Apoptosis Cancer Inflammation/Immunology
    Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).
  • HY-14519D
    Methotrexate monohydrate

    Amethopterin monohydrate; CL14377 monohydrate; WR19039 monohydrate

    Antifolate DNA/RNA Synthesis ADC Cytotoxin Apoptosis Cancer Inflammation/Immunology
    Methotrexate (Amethopterin) monohydrate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate monohydrate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).
  • HY-14519A
    Methotrexate disodium

    Amethopterin disodium; CL14377 disodium; WR19039 disodium

    Antifolate DNA/RNA Synthesis ADC Cytotoxin Apoptosis Cancer Inflammation/Immunology
    Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).
  • HY-130569S
    7-Hydroxymethotrexate-d3 sodium

    Drug Metabolite Cancer Inflammation/Immunology
    7-Hydroxymethotrexate-d3 (sodium) is deuterium labeled 7-Hydroxymethotrexate. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.
  • HY-W440890
    DSPE-PEG-Folate (MW 5000)

    Others Cancer
    DSPE-PEG-Folate (MW 5000) is a PEG derivative containing folic acid. DSPE-PEG-Folate (MW 5000) has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate (MW 5000) form micelles/lipid bilayer and can be used to targeted drug delivery system research.
  • HY-14519S
    Methotrexate-d3

    Antifolate DNA/RNA Synthesis ADC Cytotoxin Apoptosis Cancer Inflammation/Immunology
    Methotrexate-d3 (Amethopterin-d3) is the deuterium labeled Methotrexate. Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).
  • HY-113046S
    5-Methyltetrahydrofolic acid-13C5

    5-Methyl THF-13C5

    Endogenous Metabolite Metabolic Disease
    5-Methyltetrahydrofolic acid-13C5 is the 13C-labeled 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.