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gallate

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By Targets:	Apoptosis (3) Autophagy (3) Bacterial (3) COX (4) Endogenous Metabolite (4) Ferroptosis (1) HIV (1) HSV (1) Isotope-Labeled Compounds (1) Mitochondrial Metabolism (1) MMP (1) Notch (1) Oxidative Phosphorylation (1) Parasite (1) Reactive Oxygen Species (1) Telomerase (1) Virus Protease (2)
By Research Areas:	Cancer (14) Cardiovascular Disease (1) Infection (4) Inflammation/Immunology (5) Metabolic Disease (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-124082

Dodecyl gallate Lauryl gallate	Others	Infection
Dodecyl gallate (Lauryl gallate) has been widely used as an antioxidant in food manufacturing, as well as in the pharmaceutical and cosmetic industries. Dodecyl gallate also is active against a highly relevant animal virus such as African swine fever virus (ASFV) .

HY-N0002

(-)-Epicatechin gallate 4 Publications Verification Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate	COX Autophagy Virus Protease	Cancer
(-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC₅₀ of 7.5 μM.

HY-N0356

(-)-Catechin gallate 1 Publications Verification (-)-Catechin 3-gallate; (-)-Catechin 3-O-gallate	COX	Cancer
(-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes.

HY-N8129

Rhaponticin 6′′-O-gallate	Others	Others
Rhaponticin 6′′-O-gallate is a stilbene glucoside gallate that can be found in rhizome of Rheum undulatum L. Rhaponticin 6′′-O-gallate* inhibits nitric oxide production in lipopolysaccharide-activated macrophages .*

HY-N0002R

*(-)-Epicatechin gallate* (Standard)** Epicatechin gallate(Standard); ECG(Standard); (-)-Epicatechin 3-O-gallate (Standard)	COX Autophagy Virus Protease	Cancer
(-)-Epicatechin gallate (Standard) is the analytical standard of (-)-Epicatechin gallate. This product is intended for research and analytical applications. (-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC₅₀ of 7.5 μM.

HY-N0245

Theaflavin-3-gallate	Others	Cancer
Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner .

HY-N0244

Theaflavin-3'-gallate	Others	Cancer
Theaflavin-3'-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3'-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3'-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner .

HY-N8082

Stearyl gallate	HSV	Infection
Stearyl gallate is an alkyl gallate with a long alkyl chain (carbon number of 18). Stearyl gallate has an antioxidant activity, and a weak antiviral activity against HSV-1 .

HY-N0524

Propyl gallate 1 Publications Verification	Others	Others
Propyl gallate is a common food antioxidant. Propyl gallate can inhibit the production of acrolein, glyoxal and methylglyoxal .

HY-N0522

(-)-Gallocatechin gallate 2 Publications Verification (-)-Gallocatechol gallate	Others	Cancer
(-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities.

HY-13653R

*(-)-Epigallocatechin Gallate* (Standard)** Maximum Cited Publications 29 Publications Verification EGCG(Standard); Epigallocatechol gallate (Standard)	Endogenous Metabolite Apoptosis	Inflammation/Immunology Cancer
(-)-Epigallocatechin Gallate (Standard) is the analytical standard of (-)-Epigallocatechin Gallate. This product is intended for research and analytical applications. (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .

HY-13653

(-)-Epigallocatechin Gallate Maximum Cited Publications 29 Publications Verification EGCG; Epigallocatechol gallate	Endogenous Metabolite Apoptosis	Inflammation/Immunology Cancer
(-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .

HY-N8125

Rhaponticin 2′′-O-gallate

Others Inflammation/Immunology

Rhaponticin 2''-O-gallate, as a stilbene glucoside gallate, inhibits NO production .

Rhaponticin 2′′-O-gallate	Others	Inflammation/Immunology
Rhaponticin 2''-O-gallate, as a stilbene glucoside gallate, inhibits NO production .

HY-13653S

*(+/-)-Epigallocatechin Gallate-13C3*	Oxidative Phosphorylation Autophagy Reactive Oxygen Species HIV Ferroptosis Mitochondrial Metabolism Endogenous Metabolite	Cancer
(+/-)-Epigallocatechin Gallate- ¹³C₃ is the ¹³C-labeled (-)-Epigallocatechin Gallate. (-)-Epigallocatechin Gallate is a tea flavonoid with potent antioxidant, antiinflammatory, and anticarcinogenic properties. (-)-Epigallocatechin Gallate is reported to inhibit EGFR signaling and thereby exert anticancer effects[1]. (-)-Epigallocatechin Gallate (EGCG) is a glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) inhibitor. Epigallocatechin-3-gallate induces oxidative phosphorylation (OXPHOS) by activating cytochrome c oxidase.

HY-N0356S

*(+/-)-Catechin Gallate-13C3*	Isotope-Labeled Compounds COX	Cancer
(+/-)-Catechin Gallate- ¹³C₃ is the ¹³C-labeled (-)-Catechin gallate. (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes.

HY-N2011

Octyl gallate n-Octyl gallate; Stabilizer GA 8
Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity . Octyl gallate (Progallin O) shows selective and sensitive fluorescent property . Octyl gallate shows a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV) and poliovirus .

HY-N0525

Ethyl gallate

1 Publications Verification

Bacterial Metabolic Disease Cancer

Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide.

Ethyl gallate 1 Publications Verification	Bacterial	Metabolic Disease Cancer
Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide.

HY-N8589

(-)-Epiafzelechin-3-O-gallate	Others	Others
(-)-Epiafzelechin-3-O-gallate is a natural product that can be isolated from the water extract of Pu-erh tea. (-)-Epiafzelechin-3-O-gallate shows antioxidant activity .

HY-N2010

Methyl gallate 1 Publications Verification Gallincin; NSC 363001
Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities.

HY-N4298

Epitheaflagallin 3-O-gallate	MMP	Metabolic Disease Inflammation/Immunology
Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts .

HY-N9790

Procyanidin B2 3,3'-di-O-gallate	Notch	Others
Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway .

HY-135652

Hexyl gallate Hexyl 3,4,5-trihydroxybenzoate	Bacterial Parasite	Infection
Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR . Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC₅₀ of 0.11 mM .

HY-N8592

4-O-Galloylquinic acid

Others Others

4-O-Galloylquinic acid is a quinic acid gallate that can be isolated from Quercus stenophylla .

4-O-Galloylquinic acid	Others	Others
4-O-Galloylquinic acid is a quinic acid gallate that can be isolated from Quercus stenophylla .

HY-N2228

(-)-Epigallocatechin-3-(3''-O-methyl) gallate (-)-EGCG-3''-O-ME
(-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product that can be isolated from the tea leaf, with strong antioxidative activity. (-)-Epigallocatechin-3-(3''-O-methyl) gallate has a strong cytotoxic activity for rat cancer cells .

HY-N6263

EGCG Octaacetate 1 Publications Verification AcEGCG; Peracetylated (-)-epigallocatechin-3-gallate	Bacterial	Infection Cardiovascular Disease Cancer
EGCG Octaacetate (AcEGCG) is a proagent of Green tea epigallocatechin-3-gallate (EGCG). EGCG Octaacetate decreases the proinflammatory mediator levels by down-regulating of PI3K/Akt/NFκB phosphorylation and p65 acetylation. EGCG Octaacetate reduces colitis-driven colon cancer in mice. EGCG octaacetate is the potential antibacterial compound for gram-positive bacteria (GPB) and gram-negative bacteria (GNB) .

HY-120145

MST-312 Telomerase Inhibitor IX	Telomerase	Cancer
MST-312 is a telomerase inhibitor. MST-312 is a chemically modified derivative of green tea epigallocatechin gallate (EGCG). MST-312 can be used for the research of cancer, such as multiple myeloma (MM) .

HY-150526

EGCG-4″-sulfate	Endogenous Metabolite Apoptosis	Inflammation/Immunology Cancer
EGCG-4″-sulfate is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate sulfate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. EGCG-4″-sulfate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0002

(-)-Epicatechin gallate 4 Publications Verification Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate	Flavonoids Microorganisms Classification of Application Fields Flavanols Source classification Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae	COX Autophagy Virus Protease
(-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC₅₀ of 7.5 μM.

HY-N0356

(-)-Catechin gallate 1 Publications Verification (-)-Catechin 3-gallate; (-)-Catechin 3-O-gallate	Flavonoids Classification of Application Fields Flavanols Source classification Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae	COX
(-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes.

HY-N0245

Theaflavin-3-gallate	Flavonoids Classification of Application Fields Flavanols Source classification Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae	Others
Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner .

HY-N8129

Rhaponticin 6′′-O-gallate	Stilbenes Classification of Application Fields Polygonaceae Source classification Other Diseases Rheum rhabarbarum Linnaeus Phenols Polyphenols Plants Disease Research Fields	Others
Rhaponticin 6′′-O-gallate is a stilbene glucoside gallate that can be found in rhizome of Rheum undulatum L. Rhaponticin 6′′-O-gallate* inhibits nitric oxide production in lipopolysaccharide-activated macrophages .*

HY-N0002R

*(-)-Epicatechin gallate* (Standard)** Epicatechin gallate(Standard); ECG(Standard); (-)-Epicatechin 3-O-gallate (Standard)	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae	COX Autophagy Virus Protease
(-)-Epicatechin gallate (Standard) is the analytical standard of (-)-Epicatechin gallate. This product is intended for research and analytical applications. (-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 (COX-1) with an IC₅₀ of 7.5 μM.

HY-N0244

Theaflavin-3'-gallate	Structural Classification Flavonoids Classification of Application Fields Flavanols Source classification Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae	Others
Theaflavin-3'-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3'-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3'-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner .

HY-N0524

Propyl gallate 1 Publications Verification	Classification of Application Fields Paeonia lactiflora Pall. Source classification Other Diseases Phenols Polyphenols Plants Paeoniaceae Disease Research Fields	Others
Propyl gallate is a common food antioxidant. Propyl gallate can inhibit the production of acrolein, glyoxal and methylglyoxal .

HY-N0522

(-)-Gallocatechin gallate 2 Publications Verification (-)-Gallocatechol gallate	Flavonoids Classification of Application Fields Flavanols Source classification Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae	Others
(-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities.

HY-13653R

*(-)-Epigallocatechin Gallate* (Standard)** Maximum Cited Publications 29 Publications Verification EGCG(Standard); Epigallocatechol gallate (Standard)	Structural Classification Flavonoids other families Classification of Application Fields Anti-aging Source classification Phenols Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
(-)-Epigallocatechin Gallate (Standard) is the analytical standard of (-)-Epigallocatechin Gallate. This product is intended for research and analytical applications. (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .

HY-13653

(-)-Epigallocatechin Gallate Maximum Cited Publications 29 Publications Verification EGCG; Epigallocatechol gallate	Structural Classification Classification of Application Fields Anti-aging Source classification Plants Endogenous metabolite Flavonoids other families Flavonones Phenols Polyphenols Inflammation/Immunology Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
(-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .

HY-N8125

Rhaponticin 2′′-O-gallate	Stilbenes Classification of Application Fields Polygonaceae Source classification Rheum officinale Baill. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Others
Rhaponticin 2''-O-gallate, as a stilbene glucoside gallate, inhibits NO production .

HY-N0525

Ethyl gallate 1 Publications Verification	Classification of Application Fields Paeonia lactiflora Pall. Source classification Phenols Polyphenols Plants Paeoniaceae Disease Research Fields Cancer	Bacterial
Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide.

HY-N8589

(-)-Epiafzelechin-3-O-gallate	Structural Classification Source classification Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Theaceae	Others
(-)-Epiafzelechin-3-O-gallate is a natural product that can be isolated from the water extract of Pu-erh tea. (-)-Epiafzelechin-3-O-gallate shows antioxidant activity .

HY-N4298

Epitheaflagallin 3-O-gallate	Classification of Application Fields Source classification Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Inflammation/Immunology Theaceae	MMP
Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts .

HY-N9790

Procyanidin B2 3,3'-di-O-gallate	Structural Classification Source classification Vitis vinifera cv. Zalema Phenols Polyphenols Plants Vitaceae	Notch
Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway .

HY-N8592

4-O-Galloylquinic acid	Structural Classification Ketones, Aldehydes, Acids Alchornea trewioides (Benth.) Muell. Arg. Source classification Phenols Polyphenols Euphorbiaceae Plants	Others
4-O-Galloylquinic acid is a quinic acid gallate that can be isolated from Quercus stenophylla .

HY-150526

EGCG-4″-sulfate	Structural Classification Flavonoids Classification of Application Fields Flavanols Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
EGCG-4″-sulfate is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate sulfate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. EGCG-4″-sulfate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .

Cat. No.	Product Name	Chemical Structure

HY-13653S

(+/-)-Epigallocatechin Gallate-13C3

(+/-)-Epigallocatechin Gallate- ¹³C₃ is the ¹³C-labeled (-)-Epigallocatechin Gallate. (-)-Epigallocatechin Gallate is a tea flavonoid with potent antioxidant, antiinflammatory, and anticarcinogenic properties. (-)-Epigallocatechin Gallate is reported to inhibit EGFR signaling and thereby exert anticancer effects[1]. (-)-Epigallocatechin Gallate (EGCG) is a glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) inhibitor. Epigallocatechin-3-gallate induces oxidative phosphorylation (OXPHOS) by activating cytochrome c oxidase.

HY-N0356S

*(+/-)-Catechin Gallate-13C3*
(+/-)-Catechin Gallate- ¹³C₃ is the ¹³C-labeled (-)-Catechin gallate. (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes.

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gallate

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Isotope-Labeled Compounds

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