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Results for "

glands

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Androgen Receptor (3) Antibiotic (1) Apoptosis (4) Autophagy (4) Bacterial (1) Beta-secretase (1) Biochemical Assay Reagents (3) Calcium Channel (1) CaSR (3) CGRP Receptor (1) Chloride Channel (1) Cholinesterase (ChE) (2) CRFR (2) DNA-PK (2) Endogenous Metabolite (13) Estrogen Receptor/ERR (1) GnRH Receptor (1) mAChR (10) MCHR1 (GPR24) (2) Melanocortin Receptor (4) Melatonin Receptor (4) Mineralocorticoid Receptor (1) Mitophagy (4) nAChR (1) Proton Pump (1) Raf (2) Thyroid Hormone Receptor (2)
By Research Areas:	Cancer (17) Cardiovascular Disease (7) Endocrinology (24) Infection (2) Inflammation/Immunology (8) Metabolic Disease (12) Neurological Disease (23)

By Targets:

Adrenergic Receptor (2)

Androgen Receptor (3)

Antibiotic (1)

Apoptosis (4)

Autophagy (4)

Bacterial (1)

Beta-secretase (1)

Biochemical Assay Reagents (3)

Calcium Channel (1)

CaSR (3)

CGRP Receptor (1)

Chloride Channel (1)

Cholinesterase (ChE) (2)

CRFR (2)

DNA-PK (2)

Endogenous Metabolite (13)

Estrogen Receptor/ERR (1)

GnRH Receptor (1)

mAChR (10)

MCHR1 (GPR24) (2)

Melanocortin Receptor (4)

Melatonin Receptor (4)

Mineralocorticoid Receptor (1)

Mitophagy (4)

nAChR (1)

Proton Pump (1)

Raf (2)

Thyroid Hormone Receptor (2)

By Research Areas:

Cancer (17)

Cardiovascular Disease (7)

Endocrinology (24)

Infection (2)

Inflammation/Immunology (8)

Metabolic Disease (12)

Neurological Disease (23)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-90010

Tolterodine tartrate Kabi-2234; PNU-200583E	mAChR	Neurological Disease
Tolterodine Tartrate (Kabi-2234; PNU-200583E) is a potent muscarinic receptor antagonist and shows selectivity for the urinary bladder over salivary glands in vivo.

HY-100414

Soraprazan 1 Publications Verification BYK61359	Proton Pump	Metabolic Disease
Soraprazan (BYK61359) is a selective, reversible K-competitive inhibitor of the H,K-ATPase (K_i=6.4 nM), with an IC₅₀ of 0.19 μM in gastric glands. Soraprazan binds to the H,K-ATPase with a Kd of 28.27 nM. Soraprazan shows immediate inhibition of acid secretion and is more than 2000-fold selective for H,K-ATPase over Na,K- and Ca-ATPases .

HY-W143531

Perfluorohexyloctane NOV03; SHR8058	Others	Inflammation/Immunology
Perfluorohexyloctane (NOV03), a semifluorinated alkane, reduces tear film instability in Meibomian gland dysfunction and evaporative dry eye disease. Perfluorohexyloctane is a long-term tamponade agent. Perfluorohexyloctane increases tear film breakup time and lipid layer thickness .

HY-148147

Metamizol Methamizole	Others	Cardiovascular Disease
Metamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity .

HY-P3567

(p-Iodo-Phe7)-ACTH (4-10)	Melanocortin Receptor	Neurological Disease
(p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats .

HY-A0234

Stepronin Prostenoglycine; TTPG; Tiase	Others	Endocrinology
Stepronin (Prostenoglycine) is an orally active expectorant (inhalation administration is preferable to oral administration). Stepronin inhibits airway secretion in vitro by reducing Cl ^- secretion from epithelial cells and mucus glycoprotein secretion from submucosal glands .

HY-113440

5-Methoxytryptophol

Endogenous Metabolite Neurological Disease

5-Methoxytryptophol is a natural indole present in the pineal gland.

5-Methoxytryptophol	Endogenous Metabolite	Neurological Disease
5-Methoxytryptophol is a natural indole present in the pineal gland.

HY-133962

Cholesteryl erucate	Biochemical Assay Reagents	Others
Cholesteryl erucate is a cholesterol ester. It has been used as a standard for the quantification of cholesteryl esters in human meibomian gland secretions.

HY-P1581

Ceratotoxin A

Bacterial Infection

Ceratotoxin A, a 29-residue peptide isolated from the accessory gland secretion fluid, with strong anti-bacterial activity.

Ceratotoxin A	Bacterial	Infection
Ceratotoxin A, a 29-residue peptide isolated from the accessory gland secretion fluid, with strong anti-bacterial activity.

HY-A0024

Tolterodine (R)-(+)-Tolterodine; (+)-Tolterodine; (R)-Tolterodine; PNU-200583	mAChR	Neurological Disease
Tolterodine(PNU-200583) is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo.

HY-107916

Thyrotropin TSH; Pretiron	Others	Metabolic Disease Endocrinology
Thyrotropin (TSH) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid .

HY-106373

Adrenocorticotropic hormone ACTH; Adrenocorticotrophic hormone	Androgen Receptor	Endocrinology
Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production .

HY-B0282

Acetylcholine chloride 5+ Cited Publications ACh chloride	nAChR Calcium Channel Endogenous Metabolite	Neurological Disease Cancer
Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) . Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro .

HY-106373A

Adrenocorticotropic hormone TFA ACTH TFA; Adrenocorticotrophic hormone TFA	Androgen Receptor	Metabolic Disease
Adrenocorticotropic hormone (ACTH) TFA is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production .

HY-136474

Amidephrine (±)-Amidephrine	Adrenergic Receptor	Endocrinology
Amidephrine is a selective agonist of alpha 1-adrenoceptor. Amidephrine inhibits inhibits monopulse field contraction of the vas deferens epithelium and prostate gland .

HY-107953

Chorionic gonadotrophin hCG; Chorionic gonadotropic hormone	Endogenous Metabolite	Endocrinology
Chorionic gonadotrophin (hCG) is a gonadotropin that can be isolated from the anterior pituitary gland. Chorionic gonadotrophin has potential applications in ovarian and follicular development .

HY-125611

Fluorogestone acetate	GnRH Receptor	Endocrinology
Fluorogestone acetate is a progesterone compound. Fluorogestone acetate inhibits ovulation and synchronizes the estrous cycle in cattle by inhibiting the release of luteinizing hormone (LH) from the pituitary gland .

HY-134400

Follicle-stimulating hormone	Others	Endocrinology
Follicle-stimulating hormone is a heterodimer glycoprotein expressed by gonadotropin in the anterior pituitary gland. Follicle-stimulating hormone affects the fertility and reproductive efficiency of animals .

HY-113414S

Deoxycorticosterone-d8	Endogenous Metabolite	Others
Deoxycorticosterone-d₈ is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor[1][2].

HY-W739521

N-Desethyloxybutynin hydrochloride	mAChR	Others
N-Desethyloxybutynin hydrochloride is an active metabolite of Oxybutynin. N-Desethyloxybutynin hydrochloride binds to mAChRs in isolated? human bladder and human parotid gland with pK_i values of 8.2 and 8.7, respectively .

HY-113414R

Deoxycorticosterone (Standard)	Endogenous Metabolite	Others
Deoxycorticosterone (Standard) is the analytical standard of Deoxycorticosterone. This product is intended for research and analytical applications. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor.

HY-109551

Lutropin	Others	Endocrinology
Lutropin is a heterodimeric glycoprotein, a hormone produced by gonadotropic cells in the anterior pituitary gland, also known as luteinizing hormone and lutrophin. Lutropin stimulates follicular development, and can be used for researching infertility .

HY-17613

Evocalcet 1 Publications Verification KHK7580	CaSR	Metabolic Disease
Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .

HY-106608

Glutaurine Litoralon	Thyroid Hormone Receptor	Neurological Disease
Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia .

HY-N7842

17-Methylstearic acid 17-Methylstearic acid; 17-Methyloctadecanoic acid	Biochemical Assay Reagents	Others
17-Methylstearic acid is a methyl-branched fatty acid that has been found in mouse meibomian glands, C. cornucopioides mushrooms, and Phytobacter species. It is also found in the aerial parts of C. ladanifer, where its concentration varies seasonally.

HY-14752

Ronacaleret SB 751689	CaSR	Metabolic Disease Endocrinology
Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret (SB 751689) is used for the study of postmenopausal osteoporosis .

HY-15104

Ronacaleret hydrochloride SB 751689A	CaSR	Metabolic Disease Endocrinology
Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis .

HY-P4848

Dermcidin-1L (human)	Antibiotic	Infection
Dermcidin-1L (human) is an antibiotic peptide secreted by sweat glands. Dermcidin-1L (human) has antimicrobial activity. Dermcidin-1L (human) can be used for the research of inflammatory skin disorders .

HY-P3219

N-Acetyloxytocin	Endogenous Metabolite	Endocrinology
N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat .

HY-113414

Deoxycorticosterone 2 Publications Verification	Endogenous Metabolite Mineralocorticoid Receptor	Others Inflammation/Immunology
Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor (rtMR) transcription with EC₅₀ of 0.16 nM . Deoxycorticosterone could acts as an immune stimulator in fish .

HY-P4413

(Des-Glu5)-ACTH (1-24) (human, bovine, rat)	Androgen Receptor	Endocrinology
(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P4456

(Des-His6)-ACTH (1-24) (human, bovine, rat)	Adrenergic Receptor	Endocrinology
(Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P1298

Sauvagine	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Sauvagine, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine is effective at releasing ACTH from rat pituitary cells. Sauvagine possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands .

HY-103302

SUN B8155	CGRP Receptor	Endocrinology
SUN B8155, a non-peptide agonist of calcitonin (CT) receptor, selectively mimics the biological actions of calcitonin. Calcitonin, a 32-amino acid peptide hormone secreted mainly from the thyroid gland, plays an important role in maintaining bone homeostasis .

HY-106608A

Glutaurine TFA Litoralon TFA	Thyroid Hormone Receptor	Neurological Disease
Glutaurine (Litoralon) TFA containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine (Litoralon) TFA, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine (Litoralon) TFA can be used for the research of antiepileptic and anti-amnesia .

HY-90010R

Tolterodine tartrate (Standard) Kabi-2234 (Standard); PNU-200583E (Standard)	mAChR	Neurological Disease
Tolterodine (tartrate) (Standard) is the analytical standard of Tolterodine (tartrate). This product is intended for research and analytical applications. Tolterodine Tartrate (Kabi-2234; PNU-200583E) is a potent muscarinic receptor antagonist and shows selectivity for the urinary bladder over salivary glands in vivo.

HY-P1298A

Sauvagine TFA	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Sauvagine TFA, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine TFA is effective at releasing ACTH from rat pituitary cells. Sauvagine TFA possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands .

HY-101329

Anthracene-9-carboxylic acid 9-Anthracenecarboxylic acid
Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca ²⁺-activated Cl ^- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells .

HY-W013215

Adrenic Acid cis-7,10,13,16-Docosatetraenoic acid	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a naturally polyunsaturated fatty acid in the adrenal gland, brain, kidney, and vasculature. Adrenic Acid can regulate the vascular tone in arteries of the adrenal cortex. Adrenic Acid also is an inflammation enhancer in non-alcoholic fatty liver disease .

HY-76772

Cevimeline hydrochloride hemihydrate SNI-2011; AF102B hydrochloride hemihydrate	mAChR	Neurological Disease Cancer
Cevimeline hydrochloride hemihydrate (SNI-2011) is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. Cevimeline hydrochloride hemihydrate stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia . Cevimeline hydrochloride hemihydrate can cross the blood-brain barrier (BBB) .

HY-70020B

Cevimeline hydrochloride AF102B hydrochloride	mAChR	Neurological Disease
Cevimeline hydrochloride (AF102B hydrochloride) is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. Cevimeline hydrochloride stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia . Cevimeline hydrochloride can cross the blood-brain barrier (BBB) .

HY-70020

Cevimeline AF102B	mAChR	Neurological Disease
Cevimeline (AF-102B) is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. Cevimeline stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia . Cevimeline can cross the blood-brain barrier (BBB) .

HY-109013

Sofpironium bromide BBI 4000	mAChR	Neurological Disease
Sofpironium bromide (BBI 4000) is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). Sofpironium bromide reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site. Sofpironium bromide also has a high afnity for the M1, M2, M4 and M5 subtypes .

HY-P1525

Melanin Concentrating Hormone, salmon MCH (salmon)	MCHR1 (GPR24)	Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology
Melanin Concentrating Hormone, salmon is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.

HY-B0075S

Melatonin-d4 N-Acetyl-5-methoxytryptamine-d₄	Melatonin Receptor Autophagy Mitophagy Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Melatonin-d₄ is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4].

HY-157528

CJ28	Endogenous Metabolite	Cancer
CJ28 is a cortisol biosynthesis inhibitor that significantly inhibits basal and stimulated cortisol production in human adrenal carcinoma cell lines. CJ28 exhibits inhibitory effects by reducing steroidogenesis and de novo cholesterol biosynthesis .

HY-W780790

(Z,Z)-3,13-Octadecadienyl acetate	Others	Others
(Z,Z)-3,13-Octadecadienyl acetate is a compound that can be isolated from the pheromone gland extracts of female S. bicingulata moths. (Z,Z)-3,13-Octadecadienyl acetate is essential for attraction of male S. bicingulata moths. (Z,Z)-3,13-Octadecadienyl acetate can be used as bait to trap male moths .

HY-P1525A

Melanin Concentrating Hormone, salmon TFA MCH (salmon) (TFA)	MCHR1 (GPR24)	Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology
Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.

HY-32067

Aceclidine Quinuclidin-3-yl acetate	mAChR	Neurological Disease
Aceclidine (Quinuclidin-3-yl acetate) is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC₅₀: 40 μM). Aceclidine is a cycloplegic agent, a surfactant, a tonicity adjustor and optionally a viscosity enhancer and an antioxidant. Aceclidine has the potential for the research of disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia .

HY-32067A

Aceclidine hydrochloride Quinuclidin-3-yl acetate hydrochloride	mAChR	Neurological Disease
Aceclidine (Quinuclidin-3-yl acetate) hydrochloride is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC₅₀: 40 μM). Aceclidine hydrochloride is a cycloplegic agent, a surfactant, a tonicity adjustor and optionally a viscosity enhancer and an antioxidant. Aceclidine hydrochloride has the potential for the research of disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia .

Cat. No.	Product Name	Type

HY-B2192

Amylase	Biochemical Assay Reagents
Amylase is an enzyme produced by pancreas and salivary glands, catalyzing the hydrolysis of starch into sugars. Amylase are broadly classified into α, β, and γ subtypes .

HY-107903

Thyroglobulin Thyroglobulin from bovine	Native Proteins
Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle .

HY-E70001

Recombinant Human Luteinizing Hormone	Biochemical Assay Reagents
Recombinant Human Luteinizing Hormone is a recombinant form of Luteinizing hormone (human) (HY-P2293). Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .

HY-133962

Cholesteryl erucate	Biochemical Assay Reagents
Cholesteryl erucate is a cholesterol ester. It has been used as a standard for the quantification of cholesteryl esters in human meibomian gland secretions.

HY-N7842

17-Methylstearic acid 17-Methylstearic acid; 17-Methyloctadecanoic acid	Biochemical Assay Reagents
17-Methylstearic acid is a methyl-branched fatty acid that has been found in mouse meibomian glands, C. cornucopioides mushrooms, and Phytobacter species. It is also found in the aerial parts of C. ladanifer, where its concentration varies seasonally.

HY-W127485

cis-9,10-Methyleneoctadecanoic Acid

DIHYDROSTERCULIC ACID

Biochemical Assay Reagents

cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and in the digestive glands of P. globosa. It is a component of the cell membrane of Staphylococcus aureus, and levels were reduced after treatment with carvacrol. cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells. It also activates protein kinase C (PKC) in a calcium-dependent manner.

Cat. No.	Product Name	Target	Research Area

HY-P2293

Luteinizing hormone (human)	Peptides	Endocrinology
Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .

HY-P0060

Tetracosactide Tetracosactrin; ACTH(1–24)	Peptides	Cancer
Tetracosactide (Tetracosactrin) is an analogue of adrenocorticotrophic hormone (ACTH), Tetracosactide can stimulate the release of corticosteroids such as cortisol from the adrenal gland. Tetracosactide is currently used for the research of ulcerative colitis and Crohn's disease, juvenile/adult rheumatoid arthritis and osteoarthrosis .

HY-P0060A

Tetracosactide acetate Tetracosactrin acetate; ACTH(1–24) acetate	Peptides	Endocrinology
Tetracosactide acetate is a synthetic peptide stimulating the release of corticosteroids such as cortisol from the adrenal gland. Tetracosactide acetate is currently used for the research of ulcerative colitis and Crohn's disease, juvenile/adult rheumatoid arthritis and osteoarthrosis .

HY-P1581

Ceratotoxin A

Bacterial Infection

Ceratotoxin A, a 29-residue peptide isolated from the accessory gland secretion fluid, with strong anti-bacterial activity.

HY-P3567

(p-Iodo-Phe7)-ACTH (4-10)	Melanocortin Receptor	Neurological Disease
(p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats .

HY-P0070

Thymus peptide C	Peptides	Inflammation/Immunology
Thymus peptide C is a hormonal agent derived from the thymus glands of young calves, which works as a substitute for the physiological functions of the thymus.

HY-P4703

Hydrin 1′

Peptides Others

Hydrin 1′ is found in the neurohypophysis of Xenopus. Hydrin 1′ possesses a considerable steroid-releasing activity in Xenopus adrenal gland in vitro .

HY-106373

Adrenocorticotropic hormone ACTH; Adrenocorticotrophic hormone	Androgen Receptor	Endocrinology
Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production .

HY-106373A

Adrenocorticotropic hormone TFA ACTH TFA; Adrenocorticotrophic hormone TFA	Androgen Receptor	Metabolic Disease
Adrenocorticotropic hormone (ACTH) TFA is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production .

HY-P3050

Helospectin II	Peptides	Cardiovascular Disease
Helospectin II is a neuropeptide of the vasoactive intestinal peptide (VIP) family. Helospectin II has vasodilatory and antihypertensive activities, and decreases blood pressure. Helospectin II is originally isolated from the salivary gland venom of the lizard Heloderma suspectum .

HY-P3053

Helospectin I	Peptides	Cardiovascular Disease
Helospectin I is a neuropeptide of the vasoactive intestinal peptide (VIP) family. Helospectin I has vasodilatory and antihypertensive activities, and decreases blood pressure. Helospectin I is originally isolated from the salivary gland venom of the lizard Heloderma suspectum .

HY-P4848

Dermcidin-1L (human)	Antibiotic	Infection
Dermcidin-1L (human) is an antibiotic peptide secreted by sweat glands. Dermcidin-1L (human) has antimicrobial activity. Dermcidin-1L (human) can be used for the research of inflammatory skin disorders .

HY-P3219

N-Acetyloxytocin	Endogenous Metabolite	Endocrinology
N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat .

HY-P4413

(Des-Glu5)-ACTH (1-24) (human, bovine, rat)	Androgen Receptor	Endocrinology
(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P4456

(Des-His6)-ACTH (1-24) (human, bovine, rat)	Adrenergic Receptor	Endocrinology
(Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P1298

Sauvagine	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Sauvagine, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine is effective at releasing ACTH from rat pituitary cells. Sauvagine possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands .

HY-P1298A

Sauvagine TFA	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Sauvagine TFA, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine TFA is effective at releasing ACTH from rat pituitary cells. Sauvagine TFA possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands .

HY-P1525

Melanin Concentrating Hormone, salmon MCH (salmon)	MCHR1 (GPR24)	Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology
Melanin Concentrating Hormone, salmon is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.

HY-P1525A

Melanin Concentrating Hormone, salmon TFA MCH (salmon) (TFA)	MCHR1 (GPR24)	Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology
Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) is a 19-amino-acid neuropeptide initially identified in the pituitary gland of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-concentrating hormone is a ligand for an orphan G protein-coupled receptor (SLC-1/GPR24) and MCHR2.

HY-P0097A

Nonapeptide-1 acetate salt 2 Publications Verification Melanostatine-5 acetate salt	Melanocortin Receptor	Metabolic Disease Endocrinology Cancer
Nonapeptide-1 (Melanostatine-5) acetate salt, a peptide hormone, is a selective antagonist of MC1R (K_i: 40 nM). Nonapeptide-1 acetate salt is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC₅₀: 2.5 nM and 11 nM, respectively). Nonapeptide-1 acetate salt inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .

HY-P0097

Nonapeptide-1 Melanostatine-5	Melanocortin Receptor	Metabolic Disease Endocrinology Cancer
Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (K_i: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC₅₀: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .

HY-P5189A

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113440

5-Methoxytryptophol	Alkaloids Structural Classification Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Indole Alkaloids	Endogenous Metabolite
5-Methoxytryptophol is a natural indole present in the pineal gland.

HY-B0282

Acetylcholine chloride 5+ Cited Publications ACh chloride	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	nAChR Calcium Channel Endogenous Metabolite
Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) . Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro .

HY-B2192

Amylase	Structural Classification Natural Products other families Microorganisms Classification of Application Fields Animals Source classification Metabolic Disease Plants Disease Research Fields	Others
Amylase is an enzyme produced by pancreas and salivary glands, catalyzing the hydrolysis of starch into sugars. Amylase are broadly classified into α, β, and γ subtypes .

HY-107953

Chorionic gonadotrophin hCG; Chorionic gonadotropic hormone	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
Chorionic gonadotrophin (hCG) is a gonadotropin that can be isolated from the anterior pituitary gland. Chorionic gonadotrophin has potential applications in ovarian and follicular development .

HY-113414R

Deoxycorticosterone (Standard)	Structural Classification Classification of Application Fields Source classification Other Diseases Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Deoxycorticosterone (Standard) is the analytical standard of Deoxycorticosterone. This product is intended for research and analytical applications. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor.

HY-113414

Deoxycorticosterone 2 Publications Verification	Structural Classification Classification of Application Fields Source classification Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite Mineralocorticoid Receptor
Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor (rtMR) transcription with EC₅₀ of 0.16 nM . Deoxycorticosterone could acts as an immune stimulator in fish .

HY-W013215

Adrenic Acid cis-7,10,13,16-Docosatetraenoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a naturally polyunsaturated fatty acid in the adrenal gland, brain, kidney, and vasculature. Adrenic Acid can regulate the vascular tone in arteries of the adrenal cortex. Adrenic Acid also is an inflammation enhancer in non-alcoholic fatty liver disease .

HY-157528

CJ28	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
CJ28 is a cortisol biosynthesis inhibitor that significantly inhibits basal and stimulated cortisol production in human adrenal carcinoma cell lines. CJ28 exhibits inhibitory effects by reducing steroidogenesis and de novo cholesterol biosynthesis .

HY-N0702

Tenuifolin	Triterpenes Structural Classification Terpenoids Source classification Polygalaceae Plants Polygala tenuifolia Willd.	Beta-secretase Cholinesterase (ChE)
Tenuifolin is effective and has a protective action. Tenuifolin inhibits β-secretase decreases Aβ protein secretion, suppresses Aβ25-35 secretion, and subsequently caspase-3 and caspase-9 become active. Tenuifolin's ability to lower AChE activity, increase at the same time, increase the ability of the upper glands, and improve the ability to read and remember. Research on tenuifolin's potential for use in urinary disease (AD).

HY-B0075

Melatonin Maximum Cited Publications 76 Publications Verification N-Acetyl-5-methoxytryptamine	Structural Classification Natural Products Neurological Disease Classification of Application Fields Other disease Anti-aging Source classification Endogenous metabolite Microorganisms Disease markers Inflammation/Immunology Disease Research Fields Cancer	Melatonin Receptor Autophagy Mitophagy Endogenous Metabolite Apoptosis
Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .

Cat. No.	Product Name	Chemical Structure

HY-B0075S

Melatonin-d4
Melatonin-d₄ is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4].

HY-B0075S2

Melatonin-d7

Melatonin-d₇ is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5].

HY-B0075S1

Melatonin-d3

Melatonin-d₃ is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5].

HY-113414S

Deoxycorticosterone-d8
Deoxycorticosterone-d₈ is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor[1][2].

HY-101329S

Anthracene-9-carboxylic acid-d9
Anthracene-9-carboxylic acid-d₉ is the deuterium labeled Anthracene-9-carboxylic acid[1]. Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells[2].

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