glucan

By Targets:	Antibiotic (6) Apoptosis (1) Bacterial (5) Biochemical Assay Reagents (2) Endogenous Metabolite (6) Fungal (9) Isotope-Labeled Compounds (2) Phospholipase (1) Reactive Oxygen Species (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (8) Infection (11) Inflammation/Immunology (2) Metabolic Disease (7)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W145521

β-1,3-Glucan β glucan	Biochemical Assay Reagents	Others
β-1,3-Glucan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-134816

D-Glucan

Biochemical Assay Reagents Others

D-Glucan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
HY-134655

D75-4590

Fungal Infection Inflammation/Immunology

D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity .

D-Glucan	Biochemical Assay Reagents	Others
D-Glucan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

D75-4590	Fungal	Infection Inflammation/Immunology
D75-4590, a pyridobenzimidazole derivative and a *β-1,6-glucan* synthesis inhibitor, possesses antifungal activity .

HY-139413

β-D-Glucan	Toll-like Receptor (TLR)	Cancer
β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery . β-d-glucan is an enteric delivery vehicle for probiotics .

HY-147295

Odetiglucan BTH 1677; Imprime PGG	Others	Inflammation/Immunology Cancer
Odetiglucan, a novel beta glucan, is a potent immunostimulant. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response .

HY-149330

HA5	Bacterial	Infection
HA5 inhibits Streptococcus mutans biofilm with an IC₅₀ value of 6.42 μM, without affecting its growth. HA5 also inhibits Streptococcus mutans glucan production and eDNA levels .

HY-N8537

Enfumafungin	Fungal	Infection
Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis .

HY-145348

MK-5204

Others Infection

MK-5204 is an orally active β-1,3-glucan synthesis inhibitor.

MK-5204	Others	Infection
MK-5204 is an orally active β-1,3-glucan synthesis inhibitor.

HY-119109

Laminaran	Others	Cancer
Laminaran is an *β-1-3-glucan* and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities . Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .

HY-16321

Micafungin sodium Maximum Cited Publications 12 Publications Verification FK 463 sodium	Fungal Antibiotic	Infection Cancer
Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.

HY-P3004

Endo-1,3-β-glucanase Lyticase	Endogenous Metabolite	Others
Endo-1,3-β-glucanase specifically hydrolyzes β-1,3-glycosidic bonds randomly along the β-glucan chain, and the final product is mainly glucan oligosaccharide. Endo-1,3-β-glucanase is produced by a variety of fungi, is often used in biochemical studies .

HY-17579

Micafungin

FK463
Fungal Antibiotic Infection Cancer

Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.

Micafungin FK463	Fungal Antibiotic	Infection Cancer
Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.

HY-W050145

Levoglucosan 1,6-Anhydro-β-D-glucopyranose; 1,6-Anhydro-β-D-glucose	Endogenous Metabolite	Metabolic Disease
Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-E70013

Lichenase, Microorganism endo-1,3:1,4-β-D-glucanase	Endogenous Metabolite	Metabolic Disease
Lichenase, Microorganism (endo-1,3:1,4-β-D-Glucanase) is a specific, endo-(1-3),(1-4)-β-D-glucan 4-glucanohydrolase. Lichenase, Microorganism solubilizes β-glucans from cereal grains and gives gluco-oligosaccharides (GOS). Lichenase, Microorganism can be used in the degradation of polysaccharides in the cell walls .

HY-N6653

Lentinan 2 Publications Verification	Others	Cancer
Lentinan is purified β-glucan from Shiitake mushrooms. Lentinan has been approved as a biological response modifier for gastric cancer in Japan .

HY-17006A

Caspofungin MK-0991; L-743872	Antibiotic Fungal Bacterial	Infection
Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-17006

Caspofungin diacetate 3 Publications Verification MK-0991 diacetate; L-743872 diacetate	Fungal Antibiotic Bacterial	Infection Cancer
Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-W050145S

Levoglucosan-d7 1,6-Anhydro-β-D-glucopyranose-d₇; 1,6-Anhydro-β-D-glucose-d₇	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Levoglucosan-d₇ is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[1][2].

HY-W050145S2

Levoglucosan-13C6 1,6-Anhydro-β-D-glucopyranose-¹³C₆; 1,6-Anhydro-β-D-glucose-¹³C₆	Endogenous Metabolite	Metabolic Disease
Levoglucosan- ¹³C₆ is the ¹³C labeled Levoglucosan[1]. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[2].

HY-17006R

Caspofungin diacetate (Standard) MK-0991 diacetate (Standard); L-743872 diacetate (Standard)	Fungal Antibiotic Bacterial	Infection Cancer
Caspofungin (diacetate) (Standard) is the analytical standard of Caspofungin (diacetate). This product is intended for research and analytical applications. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-17006S

Caspofungin-d4 acetate MK-0991-d₄ acetate; L-743872-d₄ acetate	Fungal Bacterial Antibiotic
Caspofungin-d₄ (acetate) is the deuterium labeled Caspofungin diacetate[1]. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[2][3].

HY-P2857

Amyloglucosidase, Aspergillus niger Amyloglucosidase; 1,4-α-D-glucan glucohydrolase; Exo-1,4-α-glucosidase	Others	Metabolic Disease
Amyloglucosidase, Aspergillus niger is an enzyme derived from many sources including plants, animals and microorganisms, can be use for industrial production. Amyloglucosidase can be widely used for starch saccharification, brewing and distilling industry .

HY-P2840

Dextranase, Trichoderma reesei	Endogenous Metabolite	Metabolic Disease
Dextranase, Trichoderma reesei, glucan hydrolase, is often used in biochemical research. Dextranase can catalyze the hydrolysis of α-(1,6)-glucosidic bonds in dextran, and has a wide range of applications, such as food processing, sugar modification, agent preparation, and medicine for enhancing the activity of endocarditis antibiotics wait .

HY-17006AS

Caspofungin-d4 MK-0991-d₄; L-743872-d₄	Isotope-Labeled Compounds	Infection
Caspofungin-d₄ (MK-0991-d₄; L-743872-d₄) is a deuterium labeled Caspofungin (HY-17006A). Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .

HY-P3906

Melittin free acid	Fungal Apoptosis Phospholipase Reactive Oxygen Species	Infection
Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .

Cat. No.	Product Name	Type

HY-W145521

β-1,3-Glucan

β glucan
Biochemical Assay Reagents

β-1,3-Glucan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
HY-134816

D-Glucan

Biochemical Assay Reagents

D-Glucan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

β-1,3-Glucan β glucan	Biochemical Assay Reagents
β-1,3-Glucan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

D-Glucan	Biochemical Assay Reagents
D-Glucan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-139413

β-D-Glucan	Biochemical Assay Reagents
β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery . β-d-glucan is an enteric delivery vehicle for probiotics .

HY-P3004

Endo-1,3-β-glucanase Lyticase	Biochemical Assay Reagents
Endo-1,3-β-glucanase specifically hydrolyzes β-1,3-glycosidic bonds randomly along the β-glucan chain, and the final product is mainly glucan oligosaccharide. Endo-1,3-β-glucanase is produced by a variety of fungi, is often used in biochemical studies .

HY-N8279

β-1,3-1,4-Glucanase Endo-β-1,3-1,4-glucanase	Biochemical Assay Reagents
β-1,3-1,4-Glucanase catalyzes the hydrolysis ofβ-glucan into low molecular weight glucose polymers, thus reducing the hydrophilicity and viscosity of chyme and eliminating the anti-nutritional negative effect. β-1,3-1,4-glucanase can improve feed intake, enhance animal production, regulate cecal microbiota and increase feed conversion ratio .

Cat. No.	Product Name	Target	Research Area

HY-P3004

Endo-1,3-β-glucanase Lyticase	Endogenous Metabolite	Others
Endo-1,3-β-glucanase specifically hydrolyzes β-1,3-glycosidic bonds randomly along the β-glucan chain, and the final product is mainly glucan oligosaccharide. Endo-1,3-β-glucanase is produced by a variety of fungi, is often used in biochemical studies .

HY-P3906

Melittin free acid	Fungal Apoptosis Phospholipase Reactive Oxygen Species	Infection
Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8537

Enfumafungin	Infection Triterpenes Structural Classification Microorganisms Classification of Application Fields Terpenoids Source classification Disease Research Fields	Fungal
Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis .

HY-119109

Laminaran	Structural Classification Polysaccharides other families Microorganisms Classification of Application Fields Source classification Plants Disease Research Fields Saccharides Cancer	Others
Laminaran is an *β-1-3-glucan* and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities . Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .

HY-W050145

Levoglucosan 1,6-Anhydro-β-D-glucopyranose; 1,6-Anhydro-β-D-glucose	Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-N6653

Lentinan 2 Publications Verification	Structural Classification Polysaccharides Classification of Application Fields Agaricaceae Source classification Lentinus edodes (Berk. ) Sing Plants Disease Research Fields Saccharides Cancer	Others
Lentinan is purified β-glucan from Shiitake mushrooms. Lentinan has been approved as a biological response modifier for gastric cancer in Japan .

HY-P2857

Amyloglucosidase, Aspergillus niger Amyloglucosidase; 1,4-α-D-glucan glucohydrolase; Exo-1,4-α-glucosidase	Structural Classification Natural Products Microorganisms Classification of Application Fields Animals Source classification Metabolic Disease Disease Research Fields	Others
Amyloglucosidase, Aspergillus niger is an enzyme derived from many sources including plants, animals and microorganisms, can be use for industrial production. Amyloglucosidase can be widely used for starch saccharification, brewing and distilling industry .

Species:	Human (2) Rhesus Macaque (2) Mouse (1)
Tag:	His (3) Tag Free (1) Fc (3)
Source:	HEK293 (5) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P76722

	AMY2A Protein, Human (HEK293, His) Pancreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase	Human	HEK293
	AMY2A is a hydrolytic enzyme secreted by the pancreas that can hydrolyze α- 1,4-glycosidic bond, belonging to α- Members of the amylase family. AMY2A plays an important role in digesting dietary starch, and inhibiting AMY2A can lead to a decrease in postprandial blood glucose levels. Therefore, by regulating α- Amylase activity to control blood sugar level has therapeutic significance for diabetes, obesity and other diseases. AMY2A Protein, Human (HEK293, His) is the recombinant human-derived AMY2A protein, expressed by HEK293 , with C-His labeled tag. The total length of AMY2A Protein, Human (HEK293, His) is 496 a.a., with molecular weight of 53-58 kDa.

HY-P702148

Alpha amylase Protein, Bacillus licheniformis

amyS; Alpha-amylase; 1; 4-alpha-D-glucan glucanohydrolase; BLA
Others E. coli
HY-P702149

Alpha amylase Protein, Bacillus licheniformis (His)

amyS; Alpha-amylase; 1; 4-alpha-D-glucan glucanohydrolase; BLA
Others E. coli

HY-P76723

	AMY2A Protein, Rhesus Macaque (HEK293, Fc) Pancreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase	Rhesus Macaque	HEK293
	AMY2B is a hydrolytic enzyme secreted by the pancreas that can hydrolyze α- 1,4-glycosidic bond, belonging to α- Members of the amylase family. AMY2B plays an important role in digesting dietary starch, and inhibiting AMY2B can lead to a decrease in postprandial blood sugar levels. Therefore, by regulating α- Amylase activity to control blood sugar level has therapeutic significance for diabetes, obesity and other diseases. AMY2A Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived AMY2A protein, expressed by HEK293 , with C-hFc labeled tag. The total length of AMY2A Protein, Rhesus Macaque (HEK293, Fc) is 511 a.a., with molecular weight of ~82.8 KDa.

HY-P76724

	AMY2A Protein, Rhesus Macaque (HEK293, His) Pancreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase	Rhesus Macaque	HEK293
	AMY2B is a hydrolytic enzyme secreted by the pancreas that can hydrolyze α- 1,4-glycosidic bond, belonging to α- Members of the amylase family. AMY2B plays an important role in digesting dietary starch, and inhibiting AMY2B can lead to a decrease in postprandial blood sugar levels. Therefore, by regulating α- Amylase activity to control blood sugar level has therapeutic significance for diabetes, obesity and other diseases. AMY2A Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived AMY2A protein, expressed by HEK293 , with C-His labeled tag. The total length of AMY2A Protein, Rhesus Macaque (HEK293, His) is 511 a.a., with molecular weight of ~57.2 KDa.

HY-P700694

	Dectin-1/CLEC7A Protein, Mouse (HEK293, Fc) Beta-glucan receptor; DC-associated C-type lectin 1; Dectin-1; Dectin1; CD369; BGR; CLECSF12; DECTIN1; CANDF4	Mouse	HEK293
	Dectin-1/CLEC7A acts as a lectin and specifically recognizes β-1,3-linked and β-1,6-linked glucans in bacterial and fungal cell walls. Dectin-1/CLEC7A is critical for Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting SYK through its immunoreceptor tyrosine-based activation motif (ITAM), thereby activating NF-kappa-B. Dectin-1/CLEC7A Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with N-hFc labeled tag. The total length of Dectin-1/CLEC7A Protein, Mouse (HEK293, Fc) is 174 a.a., with molecular weight of 50-65 kDa.

HY-P70101

	Dectin-1/CLEC7A Protein, Human (HEK293, Fc) 1 Publications Verification rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; DECTIN1CANDF4	Human	HEK293
	The Dectin-1/CLEC7A protein is a lectin and pattern recognition receptor that targets β-1,3- and β-1,6-linked glucans in bacterial and fungal cell walls. It triggers Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting splenic tyrosine kinase (SYK) and activating the CARD domain-BCL10-MALT1 (CBM) signalosome. Dectin-1/CLEC7A Protein, Human (HEK293, Fc) is the recombinant human-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with N-hFc labeled tag. The total length of Dectin-1/CLEC7A Protein, Human (HEK293, Fc) is 182 a.a., with molecular weight of 50-65 kDa.

Cat. No.	Product Name	Chemical Structure

HY-W050145S

Levoglucosan-d7
Levoglucosan-d₇ is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[1][2].

HY-W050145S2

Levoglucosan-13C6
Levoglucosan- ¹³C₆ is the ¹³C labeled Levoglucosan[1]. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[2].

HY-17006S

Caspofungin-d4 acetate
Caspofungin-d₄ (acetate) is the deuterium labeled Caspofungin diacetate[1]. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[2][3].

HY-17006AS

Caspofungin-d4
Caspofungin-d₄ (MK-0991-d₄; L-743872-d₄) is a deuterium labeled Caspofungin (HY-17006A). Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .


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