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Results for "

glycoprotein-IIb

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

4

Peptides

1

Inhibitory Antibodies

1

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10309
    Sibrafiban

    RO 48-3657

    		 Integrin Cardiovascular Disease
    Sibrafiban (RO 48-3657) is the orally active, nonpeptide, double-proagent of Ro 44-3888 and a selective glycoprotein IIb/IIIa receptor antagonist. Sibrafiban inhibits platelet aggregation .
    Sibrafiban
  • HY-B0686
    Eptifibatide
    5 Publications Verification

    		 Integrin Cardiovascular Disease
    Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
    Eptifibatide
  • HY-P0074
    GPRP
    1 Publications Verification

    Gly-Pro-Arg-Pro; Pefa 6003

    		 Integrin Cardiovascular Disease
    GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .
    GPRP
  • HY-101720
    Fradafiban

    BIBU-52

    		 Integrin Cardiovascular Disease
    Fradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.
    Fradafiban
  • HY-B0686A
    Eptifibatide monoacetate

    		Integrin Cardiovascular Disease
    Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
    Eptifibatide monoacetate
  • HY-101720A
    Fradafiban hydrochloride

    BIBU-52 hydrochloride

    		 Integrin Cardiovascular Disease
    Fradafiban (BIBU-52) hydrochloride is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.
    Fradafiban hydrochloride
  • HY-P0074A
    GPRP acetate
    1 Publications Verification

    Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate

    		 Integrin Cardiovascular Disease
    GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .
    GPRP acetate
  • HY-P9934
    Abciximab

    C7E3

    		 Integrin Cardiovascular Disease
    Abciximab (C7E3), a chimeric mouse/human monoclonal antibody, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .
    Abciximab
  • HY-U00235
    SR121566A

    		Integrin Inflammation/Immunology
    SR121566A is a novel non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC50s of 46±7.5, 56±6 and 42±3 nM, respectively.
    SR121566A
  • HY-146332
    Collagen-IN-1

    		Others Cardiovascular Disease
    Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research .
    Collagen-IN-1

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