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hair

" in MedChemExpress (MCE) Product Catalog:

42

Inhibitors & Agonists

1

Fluorescent Dye

4

Biochemical Assay Reagents

13

Peptides

7

Natural
Products

1

Recombinant Proteins

4

Isotope-Labeled Compounds

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18673
    PROTO-1

    		Others Others
    PROTO-1 is a hair cell protector and can be used in studies of ototoxicity-induced hair cell death .
    PROTO-1
  • HY-10561
    RU 58841

    PSK-3841; HMR-3841

    		 Androgen Receptor Endocrinology
    RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 has a dramatic effect on hair regrowth .
    RU 58841
  • HY-139783
    3-Campholenyl-2-butanol

    		Apoptosis Others
    3-Campholenyl-2-butanol, a synthetic sandalwood odorant, is a selective olfactory receptor OR2AT4 agonist. 3-Campholenyl-2-butanol prolongs human hair growth ex vivo by decreasing apoptosis and increasing production of the anagen-prolonging growth factor IGF-1 in the outer root sheath (ORS) .
    3-Campholenyl-2-butanol
  • HY-P5258
    Oligopeptide-41

    		EGFR Metabolic Disease
    Oligopeptide-41 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .
    Oligopeptide-41
  • HY-129677
    ORC-13661 hydrochloride

    		Others Others
    ORC-13661 hydrochloride is a hair cell protector. ORC-13661 hydrochloride protects sensory hair cells from aminoglycoside and Cisplatin (HY-17394) ototoxicity. ORC-13661 hydrochloride is a reversibly mechanoelectrical transducer (MET) channel permeant blocker .
    ORC-13661 hydrochloride
  • HY-N0322A
    Cholesterol (Water Soluble)
    Maximum Cited Publications
    20 Publications Verification

    		 Liposome Others
    Cholesterol Water Soluble can be used for the research of the effects of cholesterol on the potassium currents in inner hair cells (IHCs). Cholesterol is an integral component of the cell membrane and regulates the activity of ion channels in the lipid bilayer .
    Cholesterol (Water Soluble)
  • HY-W108953
    Myristoyl tetrapeptide-12

    		TGF-beta/Smad Metabolic Disease
    Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the linking of SMAD3 with DNA. Myristoyl tetrapeptide-12 is capable of stimulating hair growth, especially at the level of eyelashes .
    Myristoyl tetrapeptide-12
  • HY-50856S
    Deuruxolitinib

    CTP-543; Ruxolitinib d8; Deuterated Ruxolitinib

    		 JAK Inflammation/Immunology
    Deuruxolitinib, a deuterated Ruxolitinib (HY-50856), modulates the activity of JAK1/JAK2. Deuruxolitinib can be used for the research hair loss disorders (from patent WO2017192905A1, compound I) .
    Deuruxolitinib
  • HY-149296
    JAK1-IN-12

    		JAK Inflammation/Immunology
    JAK1-IN-12 is a selective inhibitor of JAK1, with IC50 of 0.0246 μM. And IC50s of 0.423 μM, 0.410 μM and 1.12 μM for JAK2, JAK3 and TYK2. JAK1-IN-12 promotes hair growth in mice. JAK1-IN-12 can be used for research of immune and inflammatory diseases .
    JAK1-IN-12
  • HY-116198
    15-PGDH-IN-2

    		15-PGDH Metabolic Disease
    15-PGDH-IN-2 (Compound 2) is a 15-PGDH inhibitor with an IC50 value of 0.274 nM. 15-PGDH-IN-2 can be used in research on hair loss, bone formation, gastric ulcer healing, and dermal wound healing .
    15-PGDH-IN-2
  • HY-N0036
    Costunolide
    4 Publications Verification

    (+)-Costunolide; Costus lactone

    		 Apoptosis Endogenous Metabolite Cancer
    Costunolide ((+)-Costunolide) is a naturally occurring sesquiterpene lactone, with antioxidative, anti-inflammatory, antiallergic, bone remodeling, neuroprotective, hair growth promoting, anticancer, and antidiabetic properties. Costunolide can induce cell cycle arrest and apoptosis on breast cancer cells .
    Costunolide
  • HY-109102
    Setafrastat

    TS-133

    		 Others Others
    Setafrastat (Compound 40) is a hair growth stimulator .
    Setafrastat
  • HY-W009081
    Tricosanoic acid

    		Endogenous Metabolite Metabolic Disease
    Tricosanoic acid is a long-chain fatty acid and shown to be a hair growth stimulant.
    Tricosanoic acid
  • HY-P5247
    Palmitoyl tetrapeptide-20

    PTP20

    		 Melanocortin Receptor Metabolic Disease Inflammation/Immunology
    Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide that is an agonist for α-MSH. Palmitoyl tetrapeptide-20 can protect follicular melanocytes and activate melanogenesis by enhancing catalase expression .
    Palmitoyl tetrapeptide-20
  • HY-135057
    Lauroylamide propylbetaine

    Lauramidopropyl betaine

    		 Others Others
    Lauroylamide propylbetaine (Lauramidopropyl betaine) is a liquid detergent for cosmetic and hair compositions to enhance viscosity and has good biodegradability .
    Lauroylamide propylbetaine
  • HY-P5253
    Octapeptide-2

    		Reactive Oxygen Species Metabolic Disease
    Octapeptide-2 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .
    Octapeptide-2
  • HY-B0744
    Eflornithine
    5+ Cited Publications

    DFMO; MDL71782; RMI71782; α-difluoromethylornithine

    		 Parasite Infection Cancer
    Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
    Eflornithine
  • HY-B0744A
    Eflornithine hydrochloride

    DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride

    		 Parasite Infection Cancer
    Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
    Eflornithine hydrochloride
  • HY-B0744B
    Eflornithine hydrochloride hydrate
    5+ Cited Publications

    DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate

    		 Parasite Cancer
    Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .
    Eflornithine hydrochloride hydrate
  • HY-B1445
    Minoxidil sulfate

    Minoxidil sulfate, a potent and ATP-sensitive K + channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo .
    Minoxidil sulfate
  • HY-N7229
    Rabdosin B

    		DNA/RNA Synthesis Cancer
    Rabdosin B is an ent-kaurene diterpenoid with anticancer effects. Rabdosin B induces DNA damage in cells, and inhibits lettuce root hair development of seedlings .
    Rabdosin B
  • HY-B1024
    DL-Panthenol

    DL-Pantothenol; DL-Pantothenyl alcohol

    		 Biochemical Assay Reagents Others
    DL-Panthenol (DL-Pantothenol) is an alcohol derivative of pantothenyl acid. DL-Panthenol exerts eyelash protection effect. DL-Panthenol is widely used in the Skin and hair conditioner research .
    DL-Panthenol
  • HY-137680
    GP4G

    Diguanoside tetraphosphate

    		 Endogenous Metabolite Others
    GP4G (Diguanoside tetraphosphate) is a symmetrical bis-diphospho nucleoside that can be isolated from the cysts of Artemia salina. GP4G is an epithelial cell and hair growth regulator .
    GP4G
  • HY-B0704S
    Azelaic acid-d14

    Nonanedioic acid-d14

    		 Endogenous Metabolite Others
    Azelaic acid-d14 is the deuterium labeled Azelaic acid[1]. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid;component of a number of hair and skin conditioners[2][3].
    Azelaic acid-d14
  • HY-160547
    PROTAC AR Degrader-5

    		Androgen Receptor Metabolic Disease
    PROTAC AR Degrader-5 (compound A46) is a potent AR PROTAC Degrader with an IC50 value of 49 nM. PROTAC AR Degrader-5 inhibits sebaceous plaque and induces hair regeneration .
    PROTAC AR Degrader-5
  • HY-N2086
    Ethyl palmitate
    1 Publications Verification

    Ethyl hexadecanoate

    		 Others Others
    Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent .
    Ethyl palmitate
  • HY-10445
    Pramiconazole

    Azoline; R126638

    		 Fungal Infection
    Pramiconazole is a broad-spectrum antifungal agent with oral activity. Pramiconazole has a good affinity for 14α-demethylase. Pramiconazole can be used in the study of fungal infections in the local skin, hair, nails, oral cavity, and genital mucosa .
    Pramiconazole
  • HY-B0112
    Minoxidil
    5 Publications Verification

    U10858

    		 Potassium Channel Endogenous Metabolite Cardiovascular Disease Cancer
    Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM .
    Minoxidil
  • HY-W127338
    Butyl Palmitate

    		Biochemical Assay Reagents Others
    Butyl Palmitate is an ester compound commonly used as a conditioning, emollient or fragrance in a variety of cosmetic and personal care products. In addition, it can be used as a solvent or lubricant in various industrial applications. Its unique chemical properties make it an important ingredient in a variety of commercial products, including perfumes, lotions and hair care products.
    Butyl Palmitate
  • HY-N2086S
    Ethyl palmitate-d31

    Ethyl hexadecanoate-d31

    		 Isotope-Labeled Compounds
    Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent[1].
    Ethyl palmitate-d31
  • HY-W250580
    Dimethicone

    		Biochemical Assay Reagents Others
    Dimethicone is an orally active biochemical assay reagents consisting of a fully methylated linear siloxane polymer whose ends are blocked by trimethylsiloxane units. Dimethicone can lubricate hair and physically block the respiratory system of lice to remove lice. Dimethicone has potential applications in cosmetics and daily cleaning products .
    Dimethicone
  • HY-18237
    KX1-004

    		Src Others
    KX1-004 is a potent and non-ATP competitive Src-PTK inhibitor with an IC50 of 40 μM. KX1-004 protects the cochlea from hazardous noise and prevents noise-induced hearing loss (NIHL) .
    KX1-004
  • HY-118978
    PF-00277343

    		Thyroid Hormone Receptor Endocrinology
    PF-00277343 is a selective and skin-penetrable THR-β (Ki: 0.51 nM for THR-β, 8.0 nM for THR-α) agonist. PF-00277343 is effective against androgenetic alopecia in animal models .
    PF-00277343
  • HY-125283
    IM176OUT05

    		Mitochondrial Metabolism Metabolic Disease
    IM176OUT05 is a high solubility biguanide. IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC50 of 3.2 μM .
    IM176OUT05
  • HY-23196S
    Minoxidil-d10

    		Potassium Channel
    Minoxidil-d10 (U10858-d10) is the deuterium labeled Minoxidil. Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3].
    Minoxidil-d10
  • HY-W250194
    Luviquat FC 550

    		Biochemical Assay Reagents Others
    Luviquat FC 550 is a cationic polymer commonly used in a variety of personal care and cosmetics. It is a viscous liquid containing quaternary ammonium groups which give it a positive charge. Luviquat FC 550 has a variety of properties suitable for these applications including its ability to provide conditioning, antistatic and film-forming properties to hair and skin. In addition, it is used as a binder in oral care products and as a flocculant in industrial water treatment.
    Luviquat FC 550
  • HY-P0100
    AHK

    		Reactive Oxygen Species Inflammation/Immunology
    AHK is a bioactive peptide with antioxidant effect and has been reported used as a cosmetic ingredient .
    AHK
  • HY-160410
    Ceramide 3B

    		Others Neurological Disease Inflammation/Immunology
    Ceramide 3B is a ceramide 3 lipid class with aggregation behavior. Ceramide 3B has a variety of physiological functions and can serve as a penetration enhancer and auxiliary emulsifier, playing an important role in barrier function stability .
    Ceramide 3B
  • HY-B1005
    8-Hydroxyquinoline

    8-Quinolinol

    		 Bacterial Antibiotic Cancer
    8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice .
    8-Hydroxyquinoline
  • HY-108952
    17,17-(Ethylenedioxy)androst-4-en-3-one

    		Others Endocrinology
    17,17-(Ethylenedioxy)androst-4-en-3-one (4-​androstene-​3,​17-​dione-​17-​cyclic ethylene ketal) is an effective ingredient in cosmetics, which can be used for acne and promote hair growth research. 17,17-(Ethylenedioxy)androst-4-en-3-one can inhibit the reductase activity and inhibit the bond of a receptor protein and 5α-DHT .
    17,17-(Ethylenedioxy)androst-4-en-3-one
  • HY-13973A
    GSK-3 inhibitor 1
    1 Publications Verification

    		 GSK-3 Metabolic Disease
    GSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.g. induces stem/progenitor cell proliferation while maintaining the ability to differentiate into tissue cells in the progeny) .
    GSK-3 inhibitor 1
  • HY-D1434
    FM1-43
    1 Publications Verification

    		 Fluorescent Dye Neurological Disease
    FM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.
    FM1-43

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