Search Result

Results for "

healing

" in MedChemExpress (MCE) Product Catalog:

By Targets:	15-PGDH (1) Akt (1) Amino Acid Derivatives (2) Angiotensin Receptor (2) Antibiotic (1) Apoptosis (5) Arp2/3 Complex (1) Bacterial (10) Biochemical Assay Reagents (2) Cannabinoid Receptor (1) Carbonic Anhydrase (1) CXCR (1) E1/E2/E3 Enzyme (1) EGFR (3) Endogenous Metabolite (4) ERK (2) Estrogen Receptor/ERR (2) FAK (1) Fluorescent Dye (1) Free Fatty Acid Receptor (1) Fungal (1) GPR55 (1) GSK-3 (1) HIF/HIF Prolyl-Hydroxylase (2) Histamine Receptor (3) HSP (1) Influenza Virus (1) Interleukin Related (2) Leukotriene Receptor (2) Liposome (1) Microtubule/Tubulin (1) MMP (2) Myosin (1) Neuropeptide Y Receptor (1) PAI-1 (1) Phosphodiesterase (PDE) (1) PKA (1) Potassium Channel (1) Prostaglandin Receptor (6) Protease Activated Receptor (PAR) (3) Reactive Oxygen Species (1) ROCK (1) Separase (1) Ser/Thr Protease (2) VEGFR (1)
By Research Areas:	Cancer (19) Cardiovascular Disease (6) Endocrinology (9) Infection (16) Inflammation/Immunology (34) Metabolic Disease (11) Neurological Disease (6)

By Targets:

15-PGDH (1)

Akt (1)

Amino Acid Derivatives (2)

Angiotensin Receptor (2)

Antibiotic (1)

Apoptosis (5)

Arp2/3 Complex (1)

Bacterial (10)

Biochemical Assay Reagents (2)

Cannabinoid Receptor (1)

Carbonic Anhydrase (1)

CXCR (1)

E1/E2/E3 Enzyme (1)

EGFR (3)

Endogenous Metabolite (4)

ERK (2)

Estrogen Receptor/ERR (2)

FAK (1)

Fluorescent Dye (1)

Free Fatty Acid Receptor (1)

Fungal (1)

GPR55 (1)

GSK-3 (1)

HIF/HIF Prolyl-Hydroxylase (2)

Histamine Receptor (3)

HSP (1)

Influenza Virus (1)

Interleukin Related (2)

Leukotriene Receptor (2)

Liposome (1)

Microtubule/Tubulin (1)

MMP (2)

Myosin (1)

Neuropeptide Y Receptor (1)

PAI-1 (1)

Phosphodiesterase (PDE) (1)

PKA (1)

Potassium Channel (1)

Prostaglandin Receptor (6)

Protease Activated Receptor (PAR) (3)

Reactive Oxygen Species (1)

ROCK (1)

Separase (1)

Ser/Thr Protease (2)

VEGFR (1)

By Research Areas:

Cancer (19)

Cardiovascular Disease (6)

Endocrinology (9)

Infection (16)

Inflammation/Immunology (34)

Metabolic Disease (11)

Neurological Disease (6)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2540

(±)-Pinocembrin (±)-5,7-Dihydroxyflavanone; NSC 43318	Free Fatty Acid Receptor	Others
(±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line .

HY-P1960A

Epidermal growth factor (EGF) (phosphate) 3 Publications Verification	EGFR	Metabolic Disease Cancer
Epidermal growth factor (EGF) is a potent epidermal growth factor, stimulates the proliferation of epidermal cells and is used in wound healing applications .

HY-112362

3-(4-Pyridyl)indole Rockout; 3-(4-Pyridinyl)-1H-indole; Rho Kinase Inhibitor III, Rockout	ROCK	Inflammation/Immunology
3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC₅₀ of 25 μM. 3-(4-Pyridyl)indole can inhibit blebbing and cause dissolution of actin stress fibers in a wound healing assay .

HY-N3190

Nigracin

Poliothyrsoside; Xylosmoside
Others Others

Nigracin (Poliothyrsoside) is a phenolic glycoside compound with a wound healing activity .
HY-108281

Enfenamic acid

Tromaril; RH 8
Others Inflammation/Immunology

Enfenamic acid is a nonsteroidal anti-inflammatory agent. Enfenamic acid suppresses wound healing .

Nigracin Poliothyrsoside; Xylosmoside	Others	Others
Nigracin (Poliothyrsoside) is a phenolic glycoside compound with a wound healing activity .

Enfenamic acid Tromaril; RH 8	Others	Inflammation/Immunology
Enfenamic acid is a nonsteroidal anti-inflammatory agent. Enfenamic acid suppresses wound healing .

HY-N11901

Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside	Others	Others
Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside can be isolated from the aerial parts of the fern Ophioglossum vulgatum L and has wound healing activity .

HY-P2821

Plasminogen, Human plasma	Others	Inflammation/Immunology
Plasminogen, Human plasma is a secreted protein that upon cleavage by urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA) is converted to plasmin, a broad range protease capable of cleaving fibrin and other ECM components. Plasminogen also is a proinflammatory regulator that accelerates the healing of acute and diabetic wounds. Plasminogen can be used in studies of wound healing, inflammation and hypoplasminogenemia .

HY-N1507

Tracheloside	Estrogen Receptor/ERR	Cancer
Tracheloside is an antiestrogenic lignin. Tracheloside promotes keratinocyte proliferation through ERK1/2 stimulation. Tracheloside is a good candidate to promote wound healing .

HY-163458

Anti-inflammatory agent 77	Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 77 (C12) is a β-cycloacinamide derived mono-carbonyl curcumin analog and an inhibitor of interleukin-6 (IL-6). Anti-inflammatory agent 77 can be used in the study of wound healing .

HY-116198

15-PGDH-IN-2	15-PGDH	Metabolic Disease
15-PGDH-IN-2 (Compound 2) is a 15-PGDH inhibitor with an IC₅₀ value of 0.274 nM. 15-PGDH-IN-2 can be used in research on hair loss, bone formation, gastric ulcer healing, and dermal wound healing .

HY-135627

JBP485 cyclo(L-Hyp-L-Ser)	Endogenous Metabolite	Others
JBP485 (cyclo-trans-4-L-hydroxyprolyl-L-serine) is a dipeptide with anti-hepatotoxic and wound healing properties. JBP485 can be used for research of various kinds of corneal epithelial diseases .

HY-13710

Dimethindene	Histamine Receptor Potassium Channel Endogenous Metabolite	Neurological Disease
Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K ⁺ currents .

HY-P2463

Fequesetide	Arp2/3 Complex	Inflammation/Immunology
Fequesetide, a peptide segment, is the active site within the protein thymosin β₄ responsible for actin binding, cell migration and wound healing .

HY-134570

ZINC40099027	FAK	Metabolic Disease
ZINC40099027 is a FAK activator. ZINC40099027 promotes FAK phosphorylation, inducing mucosal healing in murine models. ZINC40099027 can be used for Gastroduodenal ulcer disease research .

HY-N2351

Paeonoside	Others	Infection Metabolic Disease Inflammation/Immunology
Paeonoside is a bioactive compound identified in P. suffruticosa that promotes wound healing and migration in osteoblast differentiation. Paeonoside has also been reported to have some antidiabetic activity and may prevent sepsis-induced lethality .

HY-124373

ND-336	MMP	Metabolic Disease
ND-336 is a selective inhibitor of matrix metalloproteinase (MMP)-2, MMP-9, and MMP-14, with K_is of 85, 150, and 120 nM, respectively. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound .

HY-W041988

Fmoc-Glu-OMe	Bacterial	Infection
Fmoc-Glu-OMe, a glutamic acid derivative, shows antibacterial activity and gelation property in AgNO₃ solution. Fmoc-Glu-OMe is a mouldable wound healing biomaterial .

HY-134636

PAPA NONOate	Endogenous Metabolite	Endocrinology
PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential research for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site .

HY-110050

GP1a	Cannabinoid Receptor	Neurological Disease Inflammation/Immunology
GP1a is a potent agonist of cannabinoid receptor 2 (CB2). Gp1a is beneficial to skin wound healing. GP1a inhibits inflammation and fibrogenesis while promoting re-epithelialization .

HY-W008956

Myoseverin	Microtubule/Tubulin	Inflammation/Immunology
Myoseverina, a microtubule-binding molecule, induces the reversible fission of multinucleated myotubes into mononucleated fragments. Myoseverina affects the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes, consistent with the activation of pathways involved in wound healing and tissue regeneration .

HY-P3259

AY254	Protease Activated Receptor (PAR)	Inflammation/Immunology Cancer
AY254 is an analogue of AY77 (HY-138951). AY254 is ERK-biased PAR2 agonist with an EC₅₀ of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling

HY-114910

11-Deoxy Prostaglandin E2	Prostaglandin Receptor	Cancer
11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC₅₀ of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions .

HY-N6580

Ginsenoside Rg4	Bacterial	Infection Metabolic Disease Inflammation/Immunology
Ginsenoside Rg4 is a major protopanaxatriol type ginsenoside isolated from the leaves of Panax ginseng C. A. Meyer. The protopanaxatriol type ginsenosides (such as Ginsenoside Rg4) exhibits various biological activities including anti-septic, anti-diabetic, wound healing, immune-stimulatory, and anti-antioxidant activity .

HY-117522

Sepin-1	Separase	Cancer
Sepin-1 is a potent separase inhibitor with an IC₅₀ value of 14.8 µM. Sepin-1 inhibits cell proliferation, migration and wound healing. Sepin-1 decreases the expression of FoxM1 protein and mRNA level. Sepin-1 shows anti-tumor activity .

HY-142521

BLT2 probe 1	Leukotriene Receptor	Metabolic Disease
BLT2 probe 1 (compound 13) is a fluorescent probe based on the synthetic BLT2 agonist CAY10583. BLT2 is a promising target for diabetic wound healing and gastrointestinal lesions. BLT2 probe 1 is suitable to investigate the pharmacology of BLT2 receptor ligands in a variety of assay systems .

HY-149837

PRO-F	Fluorescent Dye	Inflammation/Immunology
PRO-F is a photoactivable H₂S donor with ROS scavenging ability. PRO-F can be activated by light to produce fluorescent signal, for real-time tracking of released H₂S. PRO-F activation doesn’t consume endogenous substances. deliver H₂S in an intracellular environment to protect cells from excessive reactive oxygen species (ROS) induced damage. PRO-F shows enhancement on chronic wound healing, researched in diabetic models as well .

HY-16697

CID 16020046 1 Publications Verification	GPR55	Cancer
CID 16020046 is a potent and selective GPR55 antagonist and inhibits GPR55 constitutive activity with an IC₅₀ of 0.15 μM. CID 16020046 inhibits GPR55-mediated Ca ²⁺ signaling and GPR55-mediated ERK1/2 phosphorylation. CID 16020046 reduces wound healing in endothelial cells and is involved in the regulation of platelet function .

HY-B2149

Quadrol N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine; EDTP	Others	Inflammation/Immunology
Quadrol is an immunostimulant and has been implicated as a potentially useful agent in accelerated wound healing.

HY-N6577

Astragaloside VI

EGFR Neurological Disease Inflammation/Immunology

Astragaloside VI could activate EGFR/ERK signalling pathway to improve wound healing.

Astragaloside VI	EGFR	Neurological Disease Inflammation/Immunology
Astragaloside VI could activate EGFR/ERK signalling pathway to improve wound healing.

HY-106054

Nocloprost	Prostaglandin Receptor	Metabolic Disease Inflammation/Immunology
Nocloprost, a prostaglandin E2 (PGE2) analog, is an orally active EP1- and EP3-receptor agonist. Nocloprost inhibits evoked [ ³H]ACh release. Nocloprost has gastroprotective and ulcer-healing properties. Nocloprost accelerates the healing of chronic gastric ulcerations and enhances mucosal growth in rats .

HY-N6929

Angelic acid	Others	Neurological Disease
Angelic Acid is a substance found in Angelica sinensis, and it exists in an ester form. Angelic acid aids in wound healing and exhibits psychotropic properties .

HY-108249

Tribenoside	Others	Inflammation/Immunology
Tribenoside is a vasoprotective agent, can be used for the research of hemorrhoids. Tribenoside has mild anti-inflammatory, analgesic, and wound healing properties .

HY-B2191

Sodium gualenate Guaiazulenesulfonate sodium	Others	Inflammation/Immunology
Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.

HY-B1620

Polyvinylpyrrolidone PVP; Polyvidone; Povidone	Biochemical Assay Reagents	Infection
Polyvinylpyrrolidone is a compound which has been widely tested and used in human and veterinary medicine as an effective wound healing accelerator and disinfectant when combined with iodine and other compounds.

HY-N11910

Kaempferol-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside	Biochemical Assay Reagents	Others
Kaempferol-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside (Compound 3) is a wound healing agent with dose-dependent wound healing ability. Kaempferol-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside can be used for wound repair research .

HY-N2682A

(E)-Dehydrodiconiferyl alcohol	Carbonic Anhydrase	Cancer
(E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors . And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area .

HY-19864

Aganepag AGN 210937
Aganepag is a potent Prostanoid EP2 receptor agonist, with an EC₅₀ of 0.19 nM, and shows no activity at EP4 receptor. Aganepag can be used in the research of wound healing, scar reduction, scar prevention and wrinkle treatment and prevention.

HY-E70127

Serratiopeptidase Brasan; Dasen	Others	Infection
Serratiopeptidase is an anti-inflammatory agent. Serratiopeptidase has anti-inflammatory, anti-biofilm, mucolytic, fibrinolytic, and wound-healing properties. Serratiopeptidase can be used for combat COVID-19-induced respiratory syndrome research .

HY-129471

Arbaprostil	Endogenous Metabolite	Inflammation/Immunology
Arbaprostil is an orally active PGE1 (HY-B0131) analog. Arbaprostil protects the gastrointestinal mucosa from stomach acid and other irritants, promotes healing rate of gastric ucler through the antisecretory effect .

HY-15761

AZD2858 5+ Cited Publications	GSK-3	Neurological Disease
AZD2858 is a potent, orally active GSK-3 inhibitor, with IC₅₀s of 0.9 and 5 nM for GSK-3α and GSK-3β, respectively, used in the research of fracture healing.

HY-N1419

Vaccarin
Vaccarin is an active flavonoid glycoside associated with various biological functions. Vaccarin significantly promote wound healing and endothelial cells and fibroblasts proliferation in the wound site. Vaccarin ameliorates insulin resistance and steatosis by activating the AMPK signaling pathway .

HY-P5558

KLTWQELYQLKYKGI	VEGFR	Inflammation/Immunology
KLTWQELYQLKYKGI (QK) is a VEGF mimicking peptide, binds to the VEGF receptors and competes with VEGF. KLTWQELYQLKYKGI is active in gastric ulcer healing in rodents when administered either orally or systemically. KLTWQELYQLKYKGI shows the ability to induce capillary formation and organization in vitro .

HY-13813

Blebbistatin 10+ Cited Publications	Myosin	Others
Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration .

HY-P3497

Fmoc-Cys-Asp10	Amino Acid Derivatives	Others
Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .

HY-P3497A

Fmoc-Cys-Asp10 TFA	Amino Acid Derivatives	Others
Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .

HY-B0310

Nizatidine	Histamine Receptor	Inflammation/Immunology Endocrinology Cancer
Nizatidine is a potent and orally active histamine H₂ receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models .

HY-17505

Candesartan Cilexetil 2 Publications Verification TCV-116	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology
Candesartan Cilexetil (TCV-116) is an angiotensin II receptor inhibitor. Candesartan Cilexetil ameliorates the pulmonary fibrosis and has antiviral and skin wound healing effect. Candesartan Cilexetil can be used for the research of high blood pressure .

HY-B1074

Ethamsylate Etamsylate	Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Ethamsylate (Etamsylate) is an orally active anti-hemorrhagic compound. Ethamsylate inhibits biosynthesis and action of prostaglandins. Ethamsylate has the potential to maintain early hemostasis as well as restores capillary resistance. Ethamsylate acts as an antiangiogenic factor, inhibiting wound healing and matrigel tubulogenesis. .

HY-P1222

LL-37, human 2 Publications Verification	Bacterial	Infection
LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing .

HY-120435

Tyrothricin	Bacterial Fungal Influenza Virus Antibiotic	Infection
Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin shows activity against bacteria, fungi and some viruses. Tyrothricin containing formulations are used in sore throat agents and in agents for the healing of infected superficial and small-area wounds .

Cat. No.	Product Name

HY-L007

Immunology/Inflammation Compound Library

5006 compounds

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. Inflammation is also the body's attempt at self-protection to remove harmful stimuli and begin the healing process. It’s part of the body's immune response. The immune system recognizes damaged cells, irritants, and pathogens, and inflammation begins the healing process. Inflammatory abnormalities are a large group of disorders that underlie a vast variety of human diseases. The immune system is often involved with inflammatory disorders, demonstrated in both allergic reactions and some myopathies, with many immune system disorders resulting in abnormal inflammation.

MCE designs a unique collection of 5006 compounds that are useful tool for Immunology/Inflammation research or autoimmune inflammatory diseases drug discovery.

HY-L012

Metabolism/Protease Compound Library

4431 compounds

Metabolism is the set of life-sustaining chemical reactions in organisms. Metabolic pathways are enzyme-mediated biochemical reactions that lead to biosynthesis (anabolism) or breakdown (catabolism) of natural product small molecules within a cell or tissue. Acting as catalysts, enzymes are crucial to metabolism - they allow a reaction to proceed more rapidly - and they also allow the regulation of the rate of a metabolic reaction. Proteases are used throughout an organism for various metabolic processes. Proteases control a great variety of physiological processes that are critical for life, including the immune response, cell cycle, cell death, wound healing, food digestion, and protein and organelle recycling. Imbalances in metabolic activities have been found to be critical in a number of pathologies, such as cardiovascular diseases, inflammation, cancer, and neurodegenerative diseases.

MCE designs a unique collection of 4431 Metabolism/Protease-related small molecules that act as a useful tool for drug discovery of metabolism-related diseases.

HY-L088

1984 compounds

Angiogenesis is the physiological process through which new blood vessels are formed from pre-existing vessels. It occurs in various physiological processes e.g. embryonic development, menstrual cycle, exercise and wound healing etc. Angiogenesis is regulated by both endogenous activators and inhibitors. Some key activators of angiogenesis include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), angiogenin, TGF-β, etc. whereas angiogenesis inhibitors are angiostatin, endostatin, interferon, platelet factor 4, etc. The loss of balance between these opposing signals leads to life threatening diseases like cancer, cardiovascular and ischemic diseases etc. which are thus controlled by exogenous angiogenesis activators (for cardiovascular/ischemic disorders) and inhibitors (for cancer).

MCE offers a unique collection of 1984 compounds with validated angiogenesis targets modulating properties. MCE angiogenesis-related compound library is an effective tool for angiogenesis research and discovery of angiogenesis-related drugs.

HY-L174

Macrophage Related Compound Library

153 compounds

Macrophages are effector cells of the innate immune system, engulfing bacteria and secreting pro-inflammatory and antibacterial mediators. They are an important component of the first line defense against pathogens and tumor cells. In addition, macrophages play an important role in eliminating damaged cells through programmed cell death. Like all immune cells, macrophages originate from pluripotent hematopoietic stem cells in the bone marrow. Macrophages play key functions in many physiological processes beyond homeostasis and innate immunity, including metabolic function, cell debris clearance, tissue repair, and remodeling. In order to fulfill their different functional roles, macrophages can polarize into a series of phenotypes, including classic (pro inflammatory, M1) and alternative (anti-inflammatory, healing promoting, M2) activation states, as well as a wide range of regulatory phenotypes and subtypes. Macrophages exist in all vertebrate tissues and have a dual function in host protection and tissue damage, maintaining a good balance.

MCE designs a unique collection of 153 macrophage related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.

Cat. No.	Product Name	Target	Research Area

HY-P1960A

Epidermal growth factor (EGF) (phosphate) 3 Publications Verification	EGFR	Metabolic Disease Cancer
Epidermal growth factor (EGF) is a potent epidermal growth factor, stimulates the proliferation of epidermal cells and is used in wound healing applications .

HY-P2463

Fequesetide	Arp2/3 Complex	Inflammation/Immunology
Fequesetide, a peptide segment, is the active site within the protein thymosin β₄ responsible for actin binding, cell migration and wound healing .

HY-W041988

Fmoc-Glu-OMe	Bacterial	Infection
Fmoc-Glu-OMe, a glutamic acid derivative, shows antibacterial activity and gelation property in AgNO₃ solution. Fmoc-Glu-OMe is a mouldable wound healing biomaterial .

HY-P3529

G-{d-Arg}-GDSPASSK

Peptides Others

G-{d-Arg}-GDSPASSK is a polypeptide that prevents cell adhesion, is used for wound healing, and allows tissue repair .

HY-P3259

AY254	Protease Activated Receptor (PAR)	Inflammation/Immunology Cancer
AY254 is an analogue of AY77 (HY-138951). AY254 is ERK-biased PAR2 agonist with an EC₅₀ of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling

HY-P5263

YYRADDA	Peptides	Others
YYRADDA is a polypeptide. YYRADDA stimulates the growth of collagen in the extracellular matrix of the skin. YYRADDA improves the appearance of the skin and promotes the healing of damaged skin .

HY-106945

Prezatide copper Bisprezatide copper; Iamin; PC 1020	Peptides	Others
Prezatide copper (Bisprezatide copper; Iamin) is used for inhibiting hair loss. Prezatide copper also known as Iamin, is a human growth factor with multiple wound-healing properties .

HY-P4866

Q-Peptide	Peptides	Metabolic Disease
Q-Peptide is the angiopoietin-1 derived peptide (QHREDGS).Q-Peptide increases keratinocyte migration to improve wound healing, in diabetic mouse model. Q-Peptide accelerates wound closure .

HY-P5558

KLTWQELYQLKYKGI	VEGFR	Inflammation/Immunology
KLTWQELYQLKYKGI (QK) is a VEGF mimicking peptide, binds to the VEGF receptors and competes with VEGF. KLTWQELYQLKYKGI is active in gastric ulcer healing in rodents when administered either orally or systemically. KLTWQELYQLKYKGI shows the ability to induce capillary formation and organization in vitro .

HY-P3497

Fmoc-Cys-Asp10	Amino Acid Derivatives	Others
Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .

HY-P3497A

Fmoc-Cys-Asp10 TFA	Amino Acid Derivatives	Others
Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times .

HY-P1222

LL-37, human 2 Publications Verification	Bacterial	Infection
LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing .

HY-P1222B

LL-37, human acetate 2 Publications Verification	Bacterial	Infection Inflammation/Immunology
LL-37, human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human acetate could help protect the cornea from infection and modulates wound healing .

HY-P1222A

LL-37, human TFA 2 Publications Verification	Bacterial	Infection
LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and modulates wound healing .

HY-P1954

Epinecidin-1 Piscidin-1 (22-42)	Bacterial	Infection Cancer
Epinecidin-1 (Piscidin-1 (22-42)) is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .

HY-P1954A

Epinecidin-1 TFA Piscidin-1 (22-42) (TFA)	Bacterial	Infection
Epinecidin-1 (Piscidin-1 (22-42)) TFA is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 TFA has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .

HY-P1884

LL-37, acetylated,amidated	Bacterial	Infection
LL-37, acetylated, amidated is a cathelicidin peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus. The single human cathelicidin peptide LL-37 has antimicrobial and anti-biofilm activity against multiple Gram-positive and Gram-negative human pathogens, and has wound-healing effects on the host .

HY-P5356

H-D-Val-Leu-Lys-AFC Plasmin substrate	Peptides	Others
H-D-Val-Leu-Lys-AFC (Plasmin substrate) is a biological active peptide. (This is a fluorescent plasmin substrate, Abs/Em=380/500 nm.Plasmin belongs to the family of serine proteases. It plays a key role in fibrinolysis by dissolving fibrin in blood clots. Besides fibrinolysis, plasmin is also involved in such physiological and pathological processes as wound healing, liver repair, and the maintenance of liver homeostasis.)

HY-P5256

Oligopeptide-20

Bacterial Others

Oligopeptide-20 is a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient .
HY-P5257

Oligopeptide-24

CG-EDP3
Peptides Others

Oligopeptide-24 (CG-EDP3) s a bioactive peptide with skin repair effect and has been reported used as a cosmetic ingredient .

HY-P5351

Hyaluronan-binding peptide, biotin labeled	Peptides	Others
Hyaluronan-binding peptide, biotin labeled is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.)

HY-P5254

Hexapeptide-3

Peptides Metabolic Disease

Hexapeptide-3isa bioactive peptide with repair skin effect and has been reported used as a cosmetic ingredient .

HY-P3513

β-Neo-Endorphin	ERK MMP	Neurological Disease
β-Neo-Endorphin is an endogenous opioid peptide. β-Neo-Endorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. β-Neo-Endorphin shows activation of the Erk1/2, MMP-2 and MMP-9 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2540

(±)-Pinocembrin (±)-5,7-Dihydroxyflavanone; NSC 43318	Pinus strobusLinn. Flavonoids Classification of Application Fields Pinaceae Flavonones Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Free Fatty Acid Receptor
(±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line .

HY-N1507

Tracheloside	Structural Classification other families Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Disease Research Fields Cancer	Estrogen Receptor/ERR
Tracheloside is an antiestrogenic lignin. Tracheloside promotes keratinocyte proliferation through ERK1/2 stimulation. Tracheloside is a good candidate to promote wound healing .

HY-N3190

Nigracin Poliothyrsoside; Xylosmoside	Structural Classification Monophenols Source classification Phenols Flacourtiaceae Plants Xylosma racemosum (Sieb. et Zucc.) Miq.	Others
Nigracin (Poliothyrsoside) is a phenolic glycoside compound with a wound healing activity .

HY-N11901

Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside	Structural Classification Ophioglossum vulgatum L. Source classification Ophioglossaceae Phenols Polyphenols Plants	Others
Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside can be isolated from the aerial parts of the fern Ophioglossum vulgatum L and has wound healing activity .

HY-13710

Dimethindene	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Source classification Pyridine Alkaloids Endogenous metabolite Disease Research Fields	Histamine Receptor Potassium Channel Endogenous Metabolite
Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K ⁺ currents .

HY-N2351

Paeonoside	Ranunculaceae Plants Delphinium staphisagria L.	Others
Paeonoside is a bioactive compound identified in P. suffruticosa that promotes wound healing and migration in osteoblast differentiation. Paeonoside has also been reported to have some antidiabetic activity and may prevent sepsis-induced lethality .

HY-134636

PAPA NONOate	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential research for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site .

HY-N6580

Ginsenoside Rg4	Panax ginseng C. A. Meyer Triterpenes Classification of Application Fields Terpenoids Source classification Metabolic Disease Plants Disease Research Fields Inflammation/Immunology Araliaceae	Bacterial
Ginsenoside Rg4 is a major protopanaxatriol type ginsenoside isolated from the leaves of Panax ginseng C. A. Meyer. The protopanaxatriol type ginsenosides (such as Ginsenoside Rg4) exhibits various biological activities including anti-septic, anti-diabetic, wound healing, immune-stimulatory, and anti-antioxidant activity .

HY-N6577

Astragaloside VI	Triterpenes other families Leguminosae Terpenoids Source classification Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants	EGFR
Astragaloside VI could activate EGFR/ERK signalling pathway to improve wound healing.

HY-N6929

Angelic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Umbelliferae Echinacea angustifolia DC.	Others
Angelic Acid is a substance found in Angelica sinensis, and it exists in an ester form. Angelic acid aids in wound healing and exhibits psychotropic properties .

HY-N11910

Kaempferol-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside	Structural Classification Flavonoids Ophioglossum vulgatum L. Flavones Source classification Ophioglossaceae Phenols Polyphenols Plants	Biochemical Assay Reagents
Kaempferol-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside (Compound 3) is a wound healing agent with dose-dependent wound healing ability. Kaempferol-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside can be used for wound repair research .

HY-N2682A

(E)-Dehydrodiconiferyl alcohol	Monophenols Glycine soya Classification of Application Fields Source classification Lignans Phenols Cyamopsis tetragonoloba (L.) Taub. Phenylpropanoids Plants Compositae Disease Research Fields Cancer	Carbonic Anhydrase
(E)-Dehydrodiconiferyl alcohol behaves as good hCA IX and hCA XII dual inhibitors . And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area .

HY-120435

Tyrothricin	Infection Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Antiviral Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Fungal Influenza Virus Antibiotic
Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin shows activity against bacteria, fungi and some viruses. Tyrothricin containing formulations are used in sore throat agents and in agents for the healing of infected superficial and small-area wounds .

HY-N2551

Vitamin U chloride S-Methylmethionine sulfonium chloride	Plants Compositae	Others
Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration .

HY-N6613

Polygalacturonic acid Galacturonic acid polymer	Infection Structural Classification Natural Products Polysaccharides Classification of Application Fields Malus pumila Mill. Rosaceae Plants Inflammation/Immunology Disease Research Fields Saccharides	Others
Polygalacturonic acid (Galacturonic acid polymer) is transparent colloid, is a major component of the cell wall. Polygalacturonic acid can be used to prepare silver nanoparticles (AgNPs), as an antioxidant and anti-inflammatory that protect cells from destructive effect of elevated ROS and accelerate wound healing. Polygalacturonic acid nanoparticles also displays anti-bacterial activity .

HY-N6052

(+)-Medicarpin	Monophenols other families Classification of Application Fields Terpenoids Source classification Phenols Diterpenoids Plants Disease Research Fields Cancer	Estrogen Receptor/ERR
(+)-Medicarpin, a pterocarpan, is a type of isoflavonoid isolated from several medicinal plant species with various biological effects, including Sophora japonica, Zollernia paraensis and Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, and so on. (+)-Medicarpin potently inhibits osteoclastogenesis and promotes bone healing and increases bone mass by osteoblast differentiation with estrogen receptor (ER) β-mediated osteogenic action .

HY-119358

Traumatic Acid	Structural Classification Classification of Application Fields Source classification Plants Phaseolus vulgaris Linn. Cytokinin Agricultural Research Microorganisms Leguminosae Ketones, Aldehydes, Acids Phytohormone Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species Apoptosis
Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic Acid can be used in studies of cancer, circulatory disorders (including arterial hypertension), and skin diseases associated with oxidative stress and impaired collagen biosynthesis .

HY-N6613R

Polygalacturonic acid (Standard) Galacturonic acid polymer (Standard)	Structural Classification Natural Products Polysaccharides Malus pumila Mill. Rosaceae Plants Saccharides	Others
Polygalacturonic acid (Standard) is the analytical standard of Polygalacturonic acid. This product is intended for research and analytical applications. Polygalacturonic acid (Galacturonic acid polymer) is transparent colloid, is a major component of the cell wall. Polygalacturonic acid can be used to prepare silver nanoparticles (AgNPs), as an antioxidant and anti-inflammatory that protect cells from destructive effect of elevated ROS and accelerate wound healing. Polygalacturonic acid nanoparticles also displays anti-bacterial activity .

HY-113599

Isoprocurcumenol	Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Source classification Other Diseases Cosmetic Research Plants Disease Research Fields Zingiberaceae Curcuma comosa Roxb.	EGFR ERK Akt
Isoprocurcumenol is a guaiane type sesquiterpene, that can be isolated from Curcuma comosa. Isoprocurcumenol can activate EGFR signaling. Isoprocurcumenol increases the phosphorylation of ERK and AKT. Isoprocurcumenol promotes the proliferation of keratinocytes .

HY-N0976

1,11b-Dihydro-11b-hydroxymedicarpin 11b-Hydroxy-11b,1-dihydromedicarpin	Structural Classification Natural Products Classification of Application Fields Leguminosae Source classification Derris robusta Plants Inflammation/Immunology Disease Research Fields	Interleukin Related
1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative . Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways . Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice .

Cat. No.	Product Name	Chemical Structure

HY-B0310S

Nizatidine-d3
Nizatidine-d₃ is the deuterium labeled Nizatidine. Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models[1].

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