hemolysis

By Targets:	Bacterial (1) Complement System (2) DNA/RNA Synthesis (1) Fungal (4) HMG-CoA Reductase (HMGCR) (1) Phospholipase (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (5) Inflammation/Immunology (3) Metabolic Disease (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7692

Polyporusterone A	Others	Others
Polyporusterone A is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone A has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-N7693

Polyporusterone B	Others	Others
Polyporusterone B is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone B has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-P99786

Pozelimab REGN3918	Complement System	Metabolic Disease
Pozelimab (REGN3918) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab can be used for the research of complement-mediated diseases .

HY-147297

Pelecopan BCX9930	Complement System	Inflammation/Immunology
Pelecopan (BCX9930) is a potent, selective, orally active inhibitor of complement factor D with an IC₅₀ value of 14.3 nM. Pelecopan can target factor D to prevent both intravascular and extravascular hemolysis in PNH. Pelecopan also be used for other alternative pathway (AP) mediated diseases .

HY-162113

Antibacterial agent 174	Bacterial	Infection
Antibacterial agent 174 (Compound 5g) is a antibacterial agent. Antibacterial agent 174 has potent anti-infective potential in vivo and appreciable pharmacokinetic profiles. Highly active antibacterial agent 174 has favorable biofilm removal performance, low hemolysis and acceptable mammalian cell toxicity .

HY-N1449

Neonuezhenide

Neonuezhenide exhibits strong antioxidant effect against hemolysis of red blood cells induced by free radicals .

Neonuezhenide
Neonuezhenide exhibits strong antioxidant effect against hemolysis of red blood cells induced by free radicals .

HY-Y0525

AAPH 2,2'-Azodiisobutyramidine dihydrochloride
AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis .

HY-N0026

2'-Acetylacteoside 2'-AA	Others	Others
2'-Acetylacteoside is a phenylethanoid glycoside isolated from Brandisia hancei, inhibits free radical-induced hemolysis of red blood cells and exhibits free radical scavenging activity .

HY-N1947

Ligurobustoside N
Ligurobustoside N (compound 2) is an antioxidative glycoside that can be isolated from the Leaves of Ligustrum robustum. Ligurobustoside N shows antioxidant effects and shows inhibition for AAPH (HY-Y0525) induced hemolysis .

HY-123962

G6PD activator AG1 1 Publications Verification	Others	Metabolic Disease
G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) activator with an EC₅₀ of 3 µΜ . G6PD activator AG1 reduces hemolysis of human erythrocytes .

HY-135738

Convicine	Others	Others
Convicine is a pyrimidine glycoside. Convicine, as well as Vicine, is the precursor of the aglycones Divicine and Isouramil. Convicine is the main factors of favism, which is a genetic condition leading to severe hemolysis after faba bean ingestion. Convicine can be isolated from the faba bean .

HY-151437

Antifungal agent 40	Fungal	Infection
Antifungal agent 40 is an antifungal agent which extends into the narrow hydrophobic pocket II of C.alb. CYP51. Antifungal agent 40 has an inhibitory effect on lanosterol 14α-demethylase (CYP51). Antifungal agent 40 inhibits biofilm formation .

HY-151440

Antifungal agent 42	Fungal	Infection
Antifungal agent 42 is an antifungal agent. Antifungal agent 42 has an inhibitory effect on lanosterol 14α-demethylase (CYP51) of C.alb.. Antifungal agent 42 inhibits biofilm formation .

HY-151442

Antifungal agent 43	Fungal	Infection
Antifungal agent 43 (compound B05) is an antifungal agent. Antifungal agents 43 has antifungal activity by inhibiting biofilm formation. Antifungal agent 43 has low toxicity in human cancer cell lines .

HY-134082A

(Z)-Oleyloxyethyl phosphorylcholine	Phospholipase	Inflammation/Immunology
(Z)-Oleyloxyethyl phosphorylcholine ((Z)-OPC) is an isomer of Oleyloxyethyl phosphorylcholine (OPC). Oleyloxyethyl phosphorylcholine is an inhibitor of secreted Phospholipase A2 (sPLA2), which is involved in the biosynthesis of proinflammatory lipid media. Oleyloxyethyl phosphorylcholine can be used to study inflammatory diseases. Oleyloxyethyl phosphorylcholine also modified the red blood membrane and was used to bind the oxygen-carrying liquid perfluorocarbons as an antivenom agent to reduce toxin-induced hemolysis .

HY-N2923

β-Amyrin acetate	HMG-CoA Reductase (HMGCR) Fungal	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology
β-Amyrin acetate is a triterpenoid with potent anti-inflammatory, antifungal, anti-diabetic, anti-hyperlipidemic activities. β-Amyrin acetate can inhibit HMG-CoA reductase activity by locating in the hydrophobic binding cleft of HMG CoA reductase .

HY-151292

Antitumor agent-74	DNA/RNA Synthesis	Cancer
Antitumor agent-74 (compound 13da) is a quinoxalines derivative, an antitumor agent. Antitumor agent-74 exhibits more potent efficacy on tumor inhibition, mixed with regioisomer Antitumor agent-75 (HY-151295, compound 14 da) (mriBIQ 13da/14da). mriBIQ 13da/14da attests cell cycle at S phase, inhibits DNA synthesis, and induces mithochondrial apoptosis .

Cat. No.	Product Name	Target	Research Area

HY-P99786

Pozelimab REGN3918	Complement System	Metabolic Disease
Pozelimab (REGN3918) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab can be used for the research of complement-mediated diseases .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7692

Polyporusterone A	Classification of Application Fields Source classification Polyporaceae Other Diseases Poria cocos Plants Disease Research Fields Steroids	Others
Polyporusterone A is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone A has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-N7693

Polyporusterone B	Classification of Application Fields Source classification Polyporaceae Other Diseases Poria cocos Plants Disease Research Fields Steroids	Others
Polyporusterone B is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone B has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-N0026

2'-Acetylacteoside 2'-AA	Classification of Application Fields Simple Phenylpropanols Source classification Other Diseases Scrophulariaceae Phenylpropanoids Plants Disease Research Fields Brandisia hancei Hook. f.	Others
2'-Acetylacteoside is a phenylethanoid glycoside isolated from Brandisia hancei, inhibits free radical-induced hemolysis of red blood cells and exhibits free radical scavenging activity .

HY-N2923

β-Amyrin acetate	Triterpenes Structural Classification Ficus exasperata Vahl Source classification Plants Moraceae	HMG-CoA Reductase (HMGCR) Fungal
β-Amyrin acetate is a triterpenoid with potent anti-inflammatory, antifungal, anti-diabetic, anti-hyperlipidemic activities. β-Amyrin acetate can inhibit HMG-CoA reductase activity by locating in the hydrophobic binding cleft of HMG CoA reductase .

HY-135738

Convicine	Structural Classification Leguminosae Source classification Plants Vicia faba L. Saccharides Monosaccharides	Others
Convicine is a pyrimidine glycoside. Convicine, as well as Vicine, is the precursor of the aglycones Divicine and Isouramil. Convicine is the main factors of favism, which is a genetic condition leading to severe hemolysis after faba bean ingestion. Convicine can be isolated from the faba bean .

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hemolysis

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