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Results for "

hemolytic

" in MedChemExpress (MCE) Product Catalog:

55

Inhibitors & Agonists

4

Biochemical Assay Reagents

23

Peptides

2

Inhibitory Antibodies

15

Natural
Products

2

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2824

    Others Cardiovascular Disease
    Streptokinase, β-hemolytic streptococcus (Lancefield Group C) is a bacteria-derived protein and a plasminogen activator. Streptokinase is widely used for the research of the blood-clotting disorders. Streptokinase improves reperfusion blood flow after coronary artery occlusion .
    Streptokinase, β-<em>hemolytic</em> streptococcus (Lancefield Group C)
  • HY-Y0641

    m-Phenoxybenzaldehyde

    Complement System Inflammation/Immunology
    3-Phenoxybenzaldehyde has weak complement classical pathway inhibition and hemolytic activity .
    3-Phenoxybenzaldehyde
  • HY-N7666

    Others Metabolic Disease Cancer
    Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties .
    Prosaikogenin F
  • HY-P5682

    Bacterial Infection
    Maximin 41 is an antimicrobial peptide. Maximin 41 has antibacterial activity against S. aureus (MIC: 75 μg/mL). Maximin 41 has hemolytic activities against human red cells .
    Maximin 41
  • HY-P5685

    Bacterial Infection
    Maximin 49 is an antimicrobial peptide. Maximin 49 has antibacterial activity against S. aureus (MIC: 18.8 μg/mL). Maximin 49 has hemolytic activities against human and rabbit red cells .
    Maximin 49
  • HY-P5683

    Bacterial Infection
    Maximin 45 is an antimicrobial peptide. Maximin 41 has antibacterial activity against S. aureus, E. coli, B. subtilis (MIC: 4.7, 9.4, 75 μg/mL). Maximin 45 has hemolytic activities against human and rabbit red cells .
    Maximin 45
  • HY-P5686

    Bacterial Infection
    Maximin 78 is an antimicrobial peptide. Maximin 78 has antibacterial activity against C. albicans, S. aureus, B. subtilis (MIC: 37.5, 4.7, 37.5 μg/mL). Maximin 78 has hemolytic activities against human and rabbit red cells .
    Maximin 78
  • HY-P5684

    Bacterial Infection
    Maximin H39 is an antimicrobial peptide. MaximinH39 has antibacterial activity against C. albicans, S. aureus, B. subtilis (MIC: 9.4, 9.4, 18.8 μg/mL). Maximin H39 has hemolytic activities against human and rabbit red cells .
    Maximin H39
  • HY-N1446A

    Endogenous Metabolite Others
    Glycerol Monoleate is a nontoxic, biodegradable and biocompatible, lipophilic glycerol fatty acid ester. Glycerol monooleate has hemolytic properties. glycerol monooleate is used as an emulsifier and an absorption enhancer in combination with bile salts. Glycerol Monoleate can be used in drug delivery systems and siRNA delivery in Vitro .
    Glycerol Monoleate
  • HY-P5713

    Bacterial Infection
    Des(8-14)brevinin-1PMa is a host-defense peptide that exhibits antimicrobial activity against Staphylococcus aureus and Echerichia coli. Des(8-14)brevinin-1PMa also shows hemolytic activity .
    Des(8-14)brevinin-1PMa
  • HY-114524

    4-ONE

    TRP Channel Cardiovascular Disease
    (E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist .
    (E)-4-Oxo-2-nonenal
  • HY-P99365

    ALXN1210

    Complement System Metabolic Disease
    Ravulizumab (ALXN1210) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis .
    Ravulizumab
  • HY-146595

    Bacterial Infection
    FtsZ-IN-1 is a potent FtsZ inhibitor with quinolinium ring. FtsZ-IN-1 has stronger antibacterial activity against Gram-positive bacteria with MICs of 0.5-8 μg/mL. FtsZ-IN-1 significantly causes cell elongation of B. subtilis by enhancing FtsZ polymerization. FtsZ-IN-1 exhibits low hemolytic toxicity and low tendency to induce agent resistance. FtsZ-IN-1 has against drug-resistant bacteria activity .
    FtsZ-IN-1
  • HY-P2853

    Endogenous Metabolite Infection Inflammation/Immunology Cancer
    Hemocyanin is a large copper-containing respiratory protein. Hemocyanin is an important non-specific innate immune defense molecule with phenoloxidase, antiviral, antibacterial, hemolytic, and antitumor activities .
    Hemocyanin
  • HY-149223

    Bacterial Infection
    FtsZ-IN-5 is a potent FtsZ inhibitor, to promote FtsZ polymerization and inhibit GTPase activity of FtsZ. Thus, FtsZ-IN-5 inhibits bacterial division to lead to death of bacterial cells. FtsZ-IN-5 shows bactericidal activity with no significant tendency to trigger bacterial resistance as well as rapid bactericidal properties. And FtsZ-IN-5 shows low hemolytic activity and cytotoxicity to mammalian cells .
    FtsZ-IN-5
  • HY-149224

    Bacterial Infection
    FtsZ-IN-6 is a potent FtsZ inhibitor, to promote FtsZ polymerization and inhibit GTPase activity of FtsZ. Thus, FtsZ-IN-6 inhibits bacterial division to lead to death of bacterial cells. FtsZ-IN-6 shows bactericidal activity with no significant tendency to trigger bacterial resistance as well as rapid bactericidal properties. And FtsZ-IN-6 shows low hemolytic activity and cytotoxicity to mammalian cells .
    FtsZ-IN-6
  • HY-149225

    Bacterial Infection
    FtsZ-IN-7 is a potent FtsZ inhibitor, to promote FtsZ polymerization and inhibit GTPase activity of FtsZ. Thus, FtsZ-IN-7 inhibits bacterial division to lead to death of bacterial cells. FtsZ-IN-7 shows bactericidal activity with no significant tendency to trigger bacterial resistance as well as rapid bactericidal properties. And FtsZ-IN-7 shows low hemolytic activity and cytotoxicity to mammalian cells .
    FtsZ-IN-7
  • HY-149226

    Bacterial Infection
    FtsZ-IN-8 is a potent FtsZ inhibitor, to promote FtsZ polymerization and inhibit GTPase activity of FtsZ. Thus, FtsZ-IN-8 inhibits bacterial division to lead to death of bacterial cells. FtsZ-IN-8 shows bactericidal activity with no significant tendency to trigger bacterial resistance as well as rapid bactericidal properties. And FtsZ-IN-8 shows low hemolytic activity and cytotoxicity to mammalian cells .
    FtsZ-IN-8
  • HY-N9403

    Others Others
    Prosaikogenin H is an intestinal metabolite of saikosaponin with a weak hemolytic activity .
    Prosaikogenin H
  • HY-N2297

    Antibiotic Infection
    Kaji-ichigoside F1 is isolated from S. cuneata with hemolytic and in vitro antiviral activity.
    Kaji-ichigoside F1
  • HY-P1763

    Uru-TK II

    Bacterial Infection
    Urechistachykinin II (Uru-TK II), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .
    Urechistachykinin II
  • HY-P1768

    Uru-TK I

    Bacterial Infection
    Urechistachykinin I (Uru-TK I), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .
    Urechistachykinin I
  • HY-P5689

    Bacterial Infection
    Maximin 42 is an antimicrobial peptide. Maximin 42 has antibacterial activity against S. aureus (MIC: 37.5 μg/mL). Maximin 42 has hemolytic activities against human red cells .
    Maximin 42
  • HY-P5692

    Bacterial Infection
    Maximin 77 is an antimicrobial peptide. Maximin 77 has antibacterial activity against S. aureus (MIC: 18.8 μg/mL). Maximin 77 has hemolytic activities against human red cells .
    Maximin 77
  • HY-P5718

    Bacterial Infection
    Brevinin-1PMa is a host-defense peptide that exhibits antimicrobial activity against Staphylococcus aureus and Echerichia coli. Brevinin-1PMa also shows hemolytic activity .
    Brevinin-1PMa
  • HY-P5687

    Bacterial Infection
    Im5, an antimicrobial peptide, has antibacterial (MIC: 10, 2.5-5, 0.5-1 μM for E. coli, S. aureus, B. subtilis respectively) and hemolytic activity (EC50: 28 μM) .
    Im5
  • HY-P4211

    Bacterial Infection
    PSM-β is a active peptide , which can be isolated from Staphylococcus epidermidis. PSM-β is an analog of staphylococcal toxins, as well as a termed phenol-soluble modulin. PSM-β has bacteriostatic and poorly hemolytic properties .
    PSM-β
  • HY-155546

    Bacterial Infection
    Antimicrobial agent-22 (THI 6c) is a multi-target broad-spectrum antibacterial agent. Antimicrobial agent-22 has low cytotoxicity, hemolytic property, rapid bactericidal ability and good anti-biofilm activity .
    Antimicrobial agent-22
  • HY-P3914

    Oct-CA(1-7)M(2-9)

    Bacterial Infection
    Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .
    Cecropin A (1-7)-Melittin A (2-9)
  • HY-146428

    Bacterial Infection
    Anti-MRSA agent 4 (compound 7a) is a potent and selective growth inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA), with MIC ≤ 0.26 µM. Anti-MRSA agent 4 exhibits no cytotoxic and no hemolytic activity in HEK293 cells .
    Anti-MRSA agent 4
  • HY-119491

    Biochemical Assay Reagents Others
    Ethyl Tricosanoate is a long-chain saturated fatty acid ethyl ester, which exists in small amounts in C. conicum and C. conicum. Free acid reduces the hemolytic activity of Staphylococcus aureus delta toxin on human erythrocytes. Both ethyl ester and free acid can be used as standards for the analysis of lipid mixtures.
    Ethyl tricosanoate
  • HY-P5016

    Antibiotic Bacterial Fungal Infection Cancer
    CRAMP-18 (mouse) is an antibiotic peptide without hemolytic activity. CRAMP-18 (mouse) has good inhibitory activity against Gram-negative bacteria, such as S. typhimurium and P. aeruginosa. CRAMP-18 (mouse) has the potential to study antifungal, antibacterial and antitumor .
    CRAMP-18 (mouse)
  • HY-N2980

    Cabraleone

    Bacterial Infection
    Ocotillone ((24S)-20,24-Epoxy-25-hydroxydammaran-3-one) is a triterpenoids that can be isolated from the fruits of Dysoxylum richii. Ocotillone has antibacterial activities against P. aeruginosa and S. typhimurium without hemolytic activity .
    Ocotillone
  • HY-E70075

    GDH-TIM; GDH-TPI

    Transketolase Metabolic Disease
    α-Glycerophosphate Dehydrogenase-Triosephosphate (GDH-TIM) is an enzyme mixture composed of glycerol phosphate dehydrogenase (GDH) and triphosphate isomerase (TIM). α-Glycerophosphate Dehydrogenase-Triosephosphate can be used to determine the activity of transketolase (TK) in hemolytic substances of red blood cells to evaluate vitamin B deficiency .
    α-Glycerophosphate Dehydrogenase-Triosephosphate
  • HY-P5688

    Bacterial Infection
    Maximin 68 is an antimicrobial peptide. Maximin 68 has antibacterial activity against C. albicans, S. aureus, E. coli, B. subtilis (MIC: 18.8, 9.4, 37.5, 9.4 μg/mL). Maximin 68 has hemolytic activities against human and rabbit red cells .
    Maximin 68
  • HY-10545

    HBV HCV Infection
    Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin, is a ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia .
    Taribavirin
  • HY-10545A

    HBV HCV Infection
    Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia .
    Taribavirin hydrochloride
  • HY-147087

    Liposome Cancer
    YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo .
    YSK 05
  • HY-135884

    AG-946; PKR activator 2

    Pyruvate Kinase Cardiovascular Disease
    Tebapivat (PKR activator 2) is a potent pyruvate kinase-R (PKR) activator extracted from patent WO2019035863A1, compound 385 .
    Tebapivat
  • HY-129555
    Surfactin
    5 Publications Verification

    Bacterial HSV Antibiotic Infection
    Surfactin is a potent cyclic lipopeptide biosurfactants consists of four isomers (Surfactin A, B, C and D), which mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects . Surfactin also has antiviral activity against a variety of enveloped viruses .
    Surfactin
  • HY-117930
    Danicopan
    3 Publications Verification

    ACH-4471

    Complement System Inflammation/Immunology
    Danicopan (ACH-4471), a selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits alternative pathway of complement (APC) activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
    Danicopan
  • HY-149844

    Fungal Infection
    S-F24 is an antifungal agent with excellent broad-spectrum. S-F24 inhibits CYP3A4 with an IC50 value of 0.4 μM. S-F24 displays a good safety profile with high selectivity, low hemolytic effects, and low tendency to induce resistance. S-F24 can be used for research on fungal infections .
    S-F24
  • HY-149881

    Bacterial Infection
    Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum Sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum Sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1 .
    Quorum Sensing-IN-2
  • HY-135883

    Pyruvate Kinase Cardiovascular Disease
    PKR activator 1 is a potent pyruvate kinase-R (PKR) activator extracted from patent WO2019035865A1, compound E7-93 .
    PKR activator 1
  • HY-P5697

    Bacterial Infection
    Tilapia piscidin 3 is an antimicrobial peptide with antibacterial activity against gram-positive and -negative bacteria (MIC: 2.44, 2.44, 9.78, 19.55, 0.61 μg/mL for V. vulnificus 204, V. alginolyticus, S. agalactiae 819, E. faecalis BCRC 10066, S. agalactiae BCRC 10787). Tilapia piscidin 3 has hemolytic activity in fish red blood cells .
    Tilapia piscidin 3
  • HY-149734

    Bacterial Infection
    MA220607 is an antibacterial agent with low hemolytic toxicity and a dual-target mechanism of action (MOA). MA220607 promotes FtsZ protein polymerization, also increases the permeability of bacterial membranes and inhibits biofilm formation. The resistance rate of MA220607 is low, and the MICs against Gram-positive bacteria and Gram-negative bacteria are Table 0.062-2 μg/mL and 0.5-4 μg/mL, respectively) .
    MA220607
  • HY-147546

    Bacterial Infection
    Antibacterial agent 107 (compound 14) is a potent antibacterial agent. Antibacterial agent 107 shows potent antibacterial activity against Gram-positive bacteria, with a MIC of 1.56 μg/mL (MRSA). Antibacterial agent 107 exhibits low hemolytic activity, high membrane selectivity, and rapid bactericidal activity. Antibacterial agent 107 shows effective in vivo efficacy in the murine model of bacterial keratitis caused by Staphylococcus aureus ATCC29213 .
    Antibacterial agent 107
  • HY-147755

    Bacterial Infection
    C16-K-cBB1 is a potent and selective antimicrobial agent for MRSA (Methicillin resistant Staphylococcus aureus), with a MIC of 1 µg/mL. C16-K-cBB1 has very good selectivity, as it has weak hemolytic activity. C16-K-cBB1 is able to kill MRSA cells in a matter of 120 min at a concentration of 12.5 μg/mL .
    C16-K-cBB1
  • HY-P5557

    Bacterial Necroptosis Cancer
    TP4 (Nile tilapia piscidin) is an orally active piscidin-like antimicrobial peptide. TP4 inhibits multiple gram positive and negative strains (MIC: 0.03-10 μg/mL). TP4 shows hemolytic activities. TP4 enhances immune response, antioxidant activity, and intestinal health against bacterial infections. TP4 also has anti-tumor effect, and induces necrosis by triggering mitochondrial dysfunction in cancer cells .
    TP4 (Nile tilapia piscidin)
  • HY-161258

    Bacterial Infection
    Antibacterial agent 181 (Compound 3f) is a potent ciprofloxacin cationic antibacterial agent with low cytotoxicity. The MIC values of Antibacterial agent 181 against Staphylococcus aureus and Escherichia coli are both 2 μg/mL .
    Antibacterial agent 181

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