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Results for "

homolog

" in MedChemExpress (MCE) Product Catalog:

38

Inhibitors & Agonists

1

Screening Libraries

1

Biochemical Assay Reagents

4

Peptides

1

Inhibitory Antibodies

287

Recombinant Proteins

2

Isotope-Labeled Compounds

141

Antibodies

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Cat. No. Compare Product Name Species Source
  • HY-P72106
    BMP-1 Protein, Human (His)

    BMP 1; BMP-1; BMP1; BMP1_HUMAN; Bone morphogenetic protein 1; Mammalian tolloid protein; mTld; OI13; PCOLC; PCP; PCP2; Procollagen C endopeptidase; Procollagen C proteinase; Procollagen C-proteinase; TLD; Tolloid; Drosophila; homolog of

    		 Human E. coli
    Bone morphogenetic protein 1 (BMP-1), also known as metalloproteinases, belongs to the BMP-1/tolloidlike proteinases (BTP) family. BMP-1 is also a signature extracellular matrix (ECM) protein associated with high metastatic potential in breast tumors. BMP-1 processes growth factors, including TGF-β, BMP-2, BMP-4, and GFD8, regulates morphogenesis, and mediates the cleavage of COOH-terminal propeptide of type I procollagen (CICP) in the extracellular space. The total length of human BMP-1 protein is 986 amino acids (M1-K986), with 4 glycosylation domains. BMP-1 Protein, Human (His) has a total length of 866 amino acids (A121-K986), is expressed in E. coli cells with a N-terminal *His-tag.
  • HY-P701698
    HIPK3 Protein, Human (Sf9, GST)

    HIPK3; Homeodomain-interacting protein kinase 3; Androgen receptor-interacting nuclear protein kinase; ANPK; Fas-interacting serine/threonine-protein kinase; FIST; homolog of protein kinase YAK1

    		 Human Sf9 insect cells
    HIPK3 is a multifaceted serine/threonine protein kinase that plays multiple roles in transcriptional regulation, apoptosis, and steroidogenic gene expression. It phosphorylates the transcription factors JUN and RUNX2, contributing to complex gene expression control. HIPK3 Protein, Human (Sf9, GST) is the recombinant human-derived HIPK3 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of HIPK3 Protein, Human (Sf9, GST) is 402 a.a., .
  • HY-P702731
    ITK Protein, Human (620a.a, sf9, GST)

    ITK; IL2-inducible T-cell kinase; tyrosine-protein kinase ITK/TSK; EMT; LYK; PSCTK2; kinase EMT; T-cell-specific kinase; tyrosine-protein kinase LYK; IL-2-inducible T cell kinase; IL-2-inducible T-cell kinase; homolog of mouse T-cell itk/tsk; interleukin-2-inducible T cell kinase; interleukin-2-inducible T-cell kinase; MGC126257; MGC126258

    		 Human Sf9 insect cells
  • HY-P72096
    ATP5F1A Protein, Human (His-SUMO)

    ATP synthase alpha chain; ATP synthase alpha chain; mitochondrial; ATP synthase subunit alpha; ATP synthase subunit alpha mitochondrial; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit 1; cardiac muscle; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; 1; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; isoform 1; cardiac muscle; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; isoform 2; non-cardiac muscle-like 2; ATP sythase F1 ATPase; alpha subunit; ATP5A; Atp5a1; ATP5AL2; ATPA_HUMAN; ATPM; Epididymis secretory sperm binding protein Li 123m; hATP1; HEL-S-123m; MC5DN4; mitochondrial; Mitochondrial ATP synthetase; Mitochondrial ATP synthetase oligomycin resistant; Modifier of Min 2; Modifier of Min 2 mouse homolog; Modifier of Min 2; mouse; homolog of; MOM2; OMR; ORM; OTTHUMP00000163475

    		 Human E. coli
    ATP5F1A is an important component of mitochondrial ATP synthase (complex V) that coordinates ATP production from ADP by utilizing the transmembrane proton gradient. As part of the F-type ATPase, the α and β subunits of ATP5F1A form the catalytic core to achieve ATP hydrolysis. ATP5F1A Protein, Human (His-SUMO) is the recombinant human-derived ATP5F1A protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of ATP5F1A Protein, Human (His-SUMO) is 510 a.a., with molecular weight of ~71.2 kDa.
  • HY-P78009
    Notch3 Protein, Human (HEK293, Fc)

    CADASIL; CASILneurogenic locus notch homolog protein 3; Notch (Drosophila) homolog 3; notch 3Notch homolog 3 (Drosophila); Notch homolog 3; Notch3; Notch-3

    		 Human HEK293
    Notch 3 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and plays a crucial regulatory role in cell fate determination. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes within the enhancer of the cleavage site. Notch3 Protein, Human (HEK293, Fc) is the recombinant human-derived Notch3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Notch3 Protein, Human (HEK293, Fc) is 428 a.a., with molecular weight of 75-83 kDa.
  • HY-P73637
    SMAD2 Protein, Mouse (sf9, His-GST)

    Mothers against decapentaplegic homolog 2; MAD homolog 2; hMAD-2; SMAD2; MADH2; MADR2

    		 Mouse Sf9 insect cells
    SMAD2 protein interacts with multiple partners, such as CREB-binding protein (CBP), EP300, SNON, and others. These interactions contribute to diverse cellular processes, including TGF-beta signaling and transcriptional regulation. SMAD2 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived SMAD2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of SMAD2 Protein, Mouse (sf9, His-GST) is 466 a.a., with molecular weight of ~90 kDa.
  • HY-P702075
    PELI2 Protein, Human

    PELI2; E3 ubiquitin-protein ligase pellino homolog 2; Pellino-2; RING-type E3 ubiquitin transferase pellino homolog 2

    		 Human E. coli
    PELI2 protein is an E3 ubiquitin ligase that links ubiquitin to substrate proteins. PELI2 Protein, Human is the recombinant human-derived PELI2 protein, expressed by E. coli , with tag free. The total length of PELI2 Protein, Human is 419 a.a., .
  • HY-P71323
    SMAD3 Protein, Human (Flag-His)
    1 Publications Verification

    Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3; SMAD3; MADH3

    		 Human E. coli
    The SMAD3 protein acts as a receptor-regulated SMAD (R-SMAD), transducing signals from TGF-β and activin type 1 receptor kinase. After being activated by antigen-presenting cells, SMAD3 binds to the TRE element in the gene promoter and forms a complex with SMAD4 to activate transcription. SMAD3 Protein, Human (Flag-His) is the recombinant human-derived SMAD3 protein, expressed by E. coli , with N-6*His, N-Flag labeled tag. The total length of SMAD3 Protein, Human (Flag-His) is 424 a.a., with molecular weight of 50-60 kDa.
  • HY-P702002
    MRE11A Protein, Human (His, GST)

    MRE11; Double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A

    		 Human E. coli
    The MRE11A protein is an important component of the DNA double-strand break repair mechanism and participates in the homologous recombination (HR) pathway. It interacts with RAD50 and NBS1 to form the MRN complex, which is essential for sensing and repairing DNA damage. MRE11A Protein, Human (His, GST) is the recombinant human-derived MRE11A protein, expressed by E. coli , with N-6*His, N-GST labeled tag. The total length of MRE11A Protein, Human (His, GST) is 411 a.a., .
  • HY-P71324
    SMAD4 Protein, Human (His)

    Mothers Against Decapentaplegic homolog 4; MAD homolog 4; Mothers Against DPP homolog 4; Deletion Target in Pancreatic Carcinoma 4; SMAD Family Member 4; SMAD 4; Smad4; hSMAD4; SMAD4; DPC4; MADH4

    		Human E. coli
    SMAD4 is a class of common mediator SMAD (Co-SMAD), which belongs to the dwarfin/SMAD family. It conducts cell signals through the SMAD4/TGF-β pathway and plays an important role in promoting bone development and tissue homeostasis. SMAD4 induces chondrogenesis of human bone marrow mesenchymal stem cells, and specifically targets stem cells to participate in self-renewal of hematopoietic stem cells. SMAD4 can also protect cell apoptosis and inhibit epithelial cell proliferation, showing antitumor effects. SMAD4 Protein, Human (His) has the 552 a.a. sequence (M1-D552), produced in E.coli with C-terminal 6*His-tag.
  • HY-P71606
    Lysyl oxidase homolog 4 Protein, Mouse (His)

    Loxl4; Loxc; Lysyl oxidase homolog 4; EC 1.4.3.-; Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C

    		 Mouse E. coli
    LOXL4 Protein potentially modulates collagenous extracellular matrix formation, suggesting a role in regulating assembly or stability of collagen fibers. Its involvement indicates a contribution to the structural integrity of tissues. The specific mechanisms and contexts of LOXL4 in collagen matrix modulation are areas of interest, emphasizing its potential significance in tissue development and maintenance. Lysyl oxidase homolog 4 Protein, Mouse (His) is the recombinant mouse-derived Lysyl oxidase homolog 4 protein, expressed by E. coli , with N-His labeled tag. The total length of Lysyl oxidase homolog 4 Protein, Mouse (His) is 732 a.a., with molecular weight of ~85.9 kDa.
  • HY-P74595
    ROBO2 Protein, Human (HEK293, His)

    Roundabout homolog 2; ROBO2; KIAA1568

    		 Human HEK293
    ROBO2 Protein, a receptor for SLIT2 and likely SLIT1, acts as a molecular guidance cue in cellular migration, especially in axonal navigation and axonal projection during neuronal development. Its interaction with SLIT2 underscores its crucial role in mediating responses to these molecular cues, indicating its essential involvement in guiding cellular movements and axonal patterning. ROBO2 Protein, Human (HEK293, His) is the recombinant human-derived ROBO2 protein, expressed by HEK293 , with C-His labeled tag. The total length of ROBO2 Protein, Human (HEK293, His) is 838 a.a., with molecular weight of ~116 kDa.
  • HY-P74880
    HN1 Protein, Mouse (His)

    Jupiter microtubule associated homolog 1; Jpt1; Hn1

    		 Mouse E. coli
    HN1 protein negatively regulates AKT-mediated GSK3B signaling and induces the phosphorylation and degradation of CTNNB1 at “Ser-33”. This effect inhibits the “Ser-9” phosphorylation of GSK3B, inhibits the activity of APC:CTNNB1:GSK3B complex and blocks its interaction with CDH1. HN1 Protein, Mouse (His) is the recombinant mouse-derived HN1 protein, expressed by E. coli , with N-His labeled tag. The total length of HN1 Protein, Mouse (His) is 154 a.a., with molecular weight of ~18.3 kDa.
  • HY-P71391
    TWSG1 Protein, Human (HEK293, His)

    Twisted Gastrulation Protein homolog 1; TWSG1; TSG

    		 Human HEK293
    The TWSG1 protein plays a dual role in BMP signaling, acting as both an antagonist and an agonist. It forms a ternary complex with CHRD and BMP, blocking BMP receptor binding, thereby antagonizing BMP signaling. TWSG1 Protein, Human (HEK293, His) is the recombinant human-derived TWSG1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TWSG1 Protein, Human (HEK293, His) is 198 a.a., with molecular weight of ~35.0 kDa.
  • HY-P77267
    TWSG1 Protein, Mouse (HEK293, His)

    Twisted Gastrulation Protein homolog 1; TWSG1; TSG

    		 Mouse HEK293
    The TWSG1 protein may contribute to the formation of the dorsal-ventral axis by counteracting BMP signaling and forming a ternary complex with CHRD and BMP to prevent BMP from binding to the receptor. Notably, TWSG1 exhibits anti-BMP and pro-BMP activities. TWSG1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TWSG1 protein, expressed by HEK293 , with C-His labeled tag. The total length of TWSG1 Protein, Mouse (HEK293, His) is 198 a.a., with molecular weight of ~34 kDa.
  • HY-P72105
    BLM Protein, Mouse (His-Myc)

    BlmBloom syndrome protein homolog; mBLM; EC 3.6.4.12; RecQ helicase homolog

    		 Mouse E. coli
    BLM is an ATP-dependent DNA helicase that can unwind single- and double-stranded DNA in the 3'-5' direction and actively participates in the DNA replication and repair process. Notably, BLM plays a critical role in 5' end resection during double-strand break repair, recruiting DNA2 to cleave 5'-ssDNA. BLM Protein, Mouse (His-Myc) is the recombinant mouse-derived BLM protein, expressed by E. coli , with N-10*His, C-Myc labeled tag. The total length of BLM Protein, Mouse (His-Myc) is 176 a.a., with molecular weight of ~24.7 kDa.
  • HY-P76839
    CNPY2 Protein, Human (HEK293, His)

    Protein canopy homolog 2; MSAP; TMEM4; ZSIG9

    		 Human HEK293
    CNPY2 Protein, a positive regulator of neurite outgrowth, stabilizes the myosin regulatory light chain (MRLC) by preventing MIR-mediated ubiquitination and proteasomal degradation. The interaction with MYLIP/MIR highlights CNPY2's crucial role in facilitating MRLC stability and promoting neurite outgrowth. CNPY2 Protein, Human (HEK293, His) is the recombinant human-derived CNPY2 protein, expressed by HEK293 , with C-His labeled tag. The total length of CNPY2 Protein, Human (HEK293, His) is 178 a.a., with molecular weight of ~19 kDa.
  • HY-P75679
    CMBL Protein, Human (His)

    Carboxymethylenebutenolidase homolog; CMBL

    		 Human E. coli
    The CMBL protein is a cysteine hydrolase that converts olmesartan medoxomil to its active form olmesartan, an angiotensin receptor blocker. It may also activate beta-lactam antibiotics such as faropenem etexil and renamcillin. CMBL Protein, Human (His) is the recombinant human-derived CMBL protein, expressed by E. coli , with N-His labeled tag. The total length of CMBL Protein, Human (His) is 245 a.a., with molecular weight of ~28 kDa.
  • HY-P74134
    Frizzled-6 Protein, Human (HEK293, His)

    Frizzled homolog 6 (Drosophila); Frizzled-6; fz-6; FZD6

    		 Human HEK293
    Frizzled-6 is a Wnt receptor that complexly activates signaling pathways that converge primarily on the β-catenin canonical pathway. This triggers disorganized protein activation, GSK-3 kinase inhibition, nuclear β-catenin accumulation, and Wnt target gene activation. Frizzled-6 Protein, Human (HEK293, His) is the recombinant human-derived Frizzled-6 protein, expressed by HEK293 , with C-His labeled tag. The total length of Frizzled-6 Protein, Human (HEK293, His) is 135 a.a., with molecular weight of ~20-28 kDa.
  • HY-P74135
    Frizzled-6 Protein, Human (HEK293, Fc)

    Frizzled homolog 6 (Drosophila); Frizzled-6; fz-6; FZD6

    		 Human HEK293
    Frizzled-6 is a Wnt receptor that complexly activates signaling pathways that converge primarily on the β-catenin canonical pathway. This triggers disorganized protein activation, GSK-3 kinase inhibition, nuclear β-catenin accumulation, and Wnt target gene activation. Frizzled-6 Protein, Human (HEK293, Fc) is the recombinant human-derived Frizzled-6 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of Frizzled-6 Protein, Human (HEK293, Fc) is 135 a.a., with molecular weight of ~42 kDa.
  • HY-P74492
    TRIB2 Protein, Human (sf9, His-GST)

    Tribbles homolog 2; TRB-2; TRIB2; TRB2

    		 Human Sf9 insect cells
    TRIB2 protein regulates MAP kinase activation by interacting with MAPK kinase, acting as a regulator without intrinsic kinase activity. Emphasizing its role in fine-tuning the MAP kinase signaling pathway. TRIB2 Protein, Human (sf9, His-GST) is the recombinant human-derived TRIB2 protein, expressed by Sf9 insect cells , with C-His, N-GST labeled tag. The total length of TRIB2 Protein, Human (sf9, His-GST) is 343 a.a., with molecular weight of ~66 kDa.
  • HY-P74540
    SMAD5 Protein, Mouse (sf9)

    Mothers against decapentaplegic homolog 5; Dwarfin-C; SMAD 5

    		 Mouse Sf9 insect cells
    SMAD5 (dwarfin C, JV5-1, MAD5) is a receptor activated Smad (R-Smad) belonging to the dwarfin/SMAD family. SMAD5 protein is activated by TGF-β receptor type I and binds to SMAD4 to form a trimer active form. SMAD5 is involved in BMP signaling pathway, regulates osteogenesis and is related to embryonic development. SMAD5 can up-regulate Runx2 expression and target osteocalcin and alkaline phosphatase (ALP) to function. SMAD5 Protein, Mouse (sf9) has 464 amino acids expressed by sf9 insect cells with tag free.
  • HY-P71262
    ROBO4 Protein, Human (HEK293, Fc)

    Roundabout homolog 4; Magic roundabout; ROBO4; UNQ421/PRO3674

    		 Human HEK293
    ROBO4 protein is a receptor for Slit proteins (especially SLIT2) and plays a crucial regulatory role in angiogenesis and blood vessel patterning. It mediates the inhibition of primary endothelial cell migration by Slit protein and helps regulate the angiogenic process. ROBO4 Protein, Human (HEK293, Fc) is the recombinant human-derived ROBO4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ROBO4 Protein, Human (HEK293, Fc) is 440 a.a., with molecular weight of ~87.0 kDa.
  • HY-P76009
    ROBO4 Protein, Human (HEK293, His)

    Roundabout homolog 4; Magic roundabout; ROBO4; UNQ421/PRO3674

    		 Human HEK293
    ROBO4 protein is a receptor for Slit proteins (especially SLIT2) and plays a crucial regulatory role in angiogenesis and blood vessel patterning. It mediates the inhibition of primary endothelial cell migration by Slit protein and helps regulate the angiogenic process. ROBO4 Protein, Human (HEK293, His) is the recombinant human-derived ROBO4 protein, expressed by HEK293 , with C-His labeled tag. The total length of ROBO4 Protein, Human (HEK293, His) is 422 a.a., with molecular weight of 55-65 kDa.
  • HY-P77339
    CNPY4/PRAT4B Protein, Human (HEK293, His)

    Protein canopy homolog 4; CNPY4; PSEC0237

    		 Human HEK293
    CNPY4/PRAT4B Protein crucially modulates TLR4 cell surface expression, impacting innate immune system regulation. Its direct interaction with TLR4 shapes Toll-like receptor signaling dynamics, essential for pathogen-associated molecular pattern recognition. By regulating TLR4 expression, CNPY4/PRAT4B fine-tunes immune cell responsiveness, contributing to the delicate balance between activation and regulation in host defense and inflammation. CNPY4/PRAT4B Protein, Human (HEK293, His) is the recombinant human-derived CNPY4/PRAT4B protein, expressed by HEK293 , with C-His labeled tag. The total length of CNPY4/PRAT4B Protein, Human (HEK293, His) is 248 a.a., with molecular weight of ~30 kDa.
  • HY-P78010
    Notch 3 Protein, Human (HEK293, His-Avi)

    CADASIL; Notch homolog 3; Notch-3; NOTCH3

    		 Human HEK293
    Notch 3 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and plays a crucial regulatory role in cell fate determination. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes within the enhancer of the cleavage site. Notch 3 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Notch 3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Notch 3 Protein, Human (HEK293, His-Avi) is 428 a.a., with molecular weight of 53-60 kDa.
  • HY-P701533
    BACH2 Protein, Human (Sf9)

    BACH2; Transcription regulator protein BACH2; BTB and CNC homolog 2

    		 Human Sf9 insect cells
    BACH2 is a multifunctional transcriptional regulator that acts as both a repressor and an activator and recognizes Maf recognition elements (MAREs) to coordinate the transcriptional regulation of MAFKs. During oxidative stress, BACH2 induces apoptosis by inhibiting HMOX1. BACH2 Protein, Human (Sf9) is the recombinant human-derived BACH2 protein, expressed by Sf9 insect cells , with tag free. The total length of BACH2 Protein, Human (Sf9) is 840 a.a., .
  • HY-P70138
    DLK-1 Protein, Human (S260N, HEK293, His)

    rHuDelta-like 1 homolog/DLK-1, His; Protein Delta homolog 1; DLK-1; pG2; DLK1; DLK

    		 Human HEK293
    DLK-1 Protein is implicated in neuroendocrine differentiation, signifying its role in cellular specialization. It acts as an inhibitor of adipocyte differentiation, regulating adipogenesis. Structurally, DLK-1 exists as a monomer, defining its molecular composition in these processes. Interactions with SH3RF2 underscore its engagement with cellular components and potential regulatory pathways. DLK-1 Protein, Human (S260N, HEK293, His) is the recombinant human-derived DLK-1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of DLK-1 Protein, Human (S260N, HEK293, His) is 274 a.a., with molecular weight of 35-45 kDa.
  • HY-P70918
    FZD2 Protein, Mouse (HEK293, Fc)

    Frizzled-2; Fz-2; mFz2; Fzd2; frizzled (Drosophila) homolog 2

    		 Mouse HEK293
    FZD2 is a Wnt receptor that primarily activates the β-catenin classical pathway, involving disheveled protein, GSK-3 kinase inhibition, nuclear β-catenin accumulation, and Wnt target gene activation. Although some family members exhibit second PKC and calcium flux pathways, the precise differentiation and integration with the canonical pathways remains unclear. FZD2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived FZD2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FZD2 Protein, Mouse (HEK293, Fc) is 140 a.a., with molecular weight of 55-60 kDa.
  • HY-P71167
    NOTCH2 Protein, Human (HEK293, His)

    AGS2; hN2; Notch homolog 2; Notch2; Notch-2; HJCYS

    		 Human HEK293
    NOTCH2 protein is a receptor for ligands such as JAG1, JAG2 and DLL1 and is critical for cell fate determination. Ligand activation promotes cleavage and releases NICD, which forms a transcription activator complex with RBPJ/RBPSUH, affecting cell differentiation, proliferation and apoptosis. NOTCH2 Protein, Human (HEK293, His) is the recombinant human-derived NOTCH2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of NOTCH2 Protein, Human (HEK293, His) is 505 a.a., with molecular weight of 60-70 kDa.
  • HY-P74146
    Frizzled-10/CD350 Protein, Human (HEK293, His)

    CD350; Frizzled homolog 10 (Drosophila); Frizzled-10; FZ-10

    		 Human HEK293
    The Frizzled-10/CD350 gene is a member of the Frizzled gene family, encoding a 7-transmembrane domain protein that acts as a receptor for the Wingless-type MMTV integration site family signaling protein. Most Frizzled receptors, including Frizzled-10/CD350, are involved in cell signaling, specifically the β-catenin classical pathway. Frizzled-10/CD350 Protein, Human (HEK293, His) is the recombinant human-derived Frizzled-10/CD350 protein, expressed by HEK293 , with C-His labeled tag. The total length of Frizzled-10/CD350 Protein, Human (HEK293, His) is 141 a.a., with molecular weight of 20-25 kDa.
  • HY-P74147
    Frizzled-10/CD350 Protein, Human (HEK293, Fc)

    CD350; Frizzled homolog 10 (Drosophila); Frizzled-10; FZ-10

    		 Human HEK293
    Frizzled-10/CD350 belongs to the G-protein coupled receptor Fz/Smo family. Frizzled-10/CD350 Protein, Human (HEK293, Fc) is the recombinant human-derived Frizzled-10/CD350 protein, expressed by HEK293, with C-hFc labeled tag. The total length of Frizzled-10/CD350 Protein, Human (HEK293, Fc) is 161 a.a., with molecular weight of ~48.7 kDa.
  • HY-P74539
    SMAD5 Protein, Mouse (sf9, His-GST)

    Mothers against decapentaplegic homolog 5; Dwarfin-C; SMAD 5

    		 Mouse Sf9 insect cells
    SMAD5 (dwarfin C, JV5-1, MAD5) is a receptor activated Smad (R-Smad) belonging to the dwarfin/SMAD family. SMAD5 protein is activated by TGF-β receptor type I and binds to SMAD4 to form a trimer active form. SMAD5 is involved in BMP signaling pathway, regulates osteogenesis and is related to embryonic development. SMAD5 can up-regulate Runx2 expression and target osteocalcin and alkaline phosphatase (ALP) to function. SMAD5 Protein, Mouse (sf9, His-GST) has 464 amino acids expressed by sf9 insect cells with N-terminal His- and GST-tag.
  • HY-P74771
    LOXL2 Protein, Human (CHO, His)

    Lysyl oxidase homolog 2; Lysyl oxidase-related protein WS9-14; LOXL2

    		 Human CHO
    LOXL2 protein mediates post-translational oxidative deamination of lysine residues, leading to the formation of allysine. It specifically deaminates H3K4me3, inhibits TFIID-dependent transcription, represses E-cadherin, activates the IRE1-XBP1 pathway, and promotes cross-linking of extracellular matrix proteins. LOXL2 is involved in EMT, tumor progression, angiogenesis regulation, and chondrocyte differentiation. LOXL2 Protein, Human (CHO, His) is the recombinant human-derived LOXL2 protein, expressed by CHO , with C-His labeled tag. The total length of LOXL2 Protein, Human (CHO, His) is 774 a.a., with molecular weight of ~85.5 kDa.
  • HY-P75970
    Pellino-1 Protein, Human (sf9, His-GST)

    E3 ubiquitin-protein ligase pellino homolog 1; PELI1; PRISM

    		 Human Sf9 insect cells
    Pellino-1 protein is an E3 ubiquitin ligase that links ubiquitin to substrate proteins. Pellino-1 Protein, Human (sf9, His-GST) is the recombinant human-derived Pellino-1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Pellino-1 Protein, Human (sf9, His-GST) is 418 a.a., with molecular weight of ~74.1 kDa.
  • HY-P76519
    NOTCH2 Protein, Human (sf9, His)

    AGS2; hN2; Notch homolog 2; Notch2; Notch-2; HJCYS

    		 Human Sf9 insect cells
    NOTCH2 protein is a receptor for ligands such as JAG1, JAG2 and DLL1 and is critical for cell fate determination. Ligand activation promotes cleavage and releases NICD, which forms a transcription activator complex with RBPJ/RBPSUH, affecting cell differentiation, proliferation and apoptosis. NOTCH2 Protein, Human (sf9, His) is the recombinant human-derived NOTCH2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of NOTCH2 Protein, Human (sf9, His) is 530 a.a., with molecular weight of ~55.5 KDa.
  • HY-P700803
    Notch 3 Protein, Human (Biotinylated, HEK293, His-Avi)

    CADASIL; Notch homolog 3; Notch-3; NOTCH3

    		 Human HEK293
    Notch 3 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and plays a crucial regulatory role in cell fate determination. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes within the enhancer of the cleavage site. Notch 3 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Notch 3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Notch 3 Protein, Human (Biotinylated, HEK293, His-Avi) is 428 a.a., with molecular weight of 55-65 kDa.
  • HY-P700804
    Notch 3 Protein, Human (HEK293, C-His-Avi)

    CADASIL; Notch homolog 3; Notch-3; NOTCH3

    		 Human HEK293
    Notch 3 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and plays a crucial regulatory role in cell fate determination. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes within the enhancer of the cleavage site. Notch 3 Protein, Human (HEK293, C-His-Avi) is the recombinant human-derived Notch 3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Notch 3 Protein, Human (HEK293, C-His-Avi) is 263 a.a., with molecular weight of 27-30 kDa & 10-12 kDa, respectively.
  • HY-P74491
    TRIB3 Protein, Human (sf9, GST)

    Tribbles homolog 3; TRB-3; SINK; C20orf97; NIPK; SKIP3

    		 Human Sf9 insect cells
    TRIB3 protein is an inactive kinase that centrally regulates the integrated stress response (ISR) and inhibits DDIT3/CHOP transcriptional activity. It causes DDIT3/CHOP-dependent cell death during endoplasmic reticulum (ER) stress, particularly in programmed neuronal cell death. TRIB3 Protein, Human (sf9, GST) is the recombinant human-derived TRIB3 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of TRIB3 Protein, Human (sf9, GST) is 358 a.a., with molecular weight of ~65.8 kDa.
  • HY-P74769
    LOXL2 Protein, Mouse (HEK293, His)

    Lysyl oxidase homolog 2; Lysyl oxidase-related protein WS9-14; LOXL2

    		 Mouse HEK293
    LOXL2 proteins play multifaceted roles in cellular processes by mediating post-translational oxidative deamination of lysine residues, leading to lysine formation. As a transcriptional corepressor, it specifically deaminates histone H3 trimethylated at "Lys-4" (H3K4me3), which is associated with transcriptional activation. LOXL2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived LOXL2 protein, expressed by HEK293 , with C-His labeled tag. The total length of LOXL2 Protein, Mouse (HEK293, His) is 751 a.a., with molecular weight of 90-100 kDa.
  • HY-P74770
    LOXL2 Protein, Human (HEK293, His)

    Lysyl oxidase homolog 2; Lysyl oxidase-related protein WS9-14; LOXL2

    		 Human HEK293
    LOXL2 protein mediates post-translational oxidative deamination of lysine residues, leading to the formation of allysine. It specifically deaminates H3K4me3, inhibits TFIID-dependent transcription, represses E-cadherin, activates the IRE1-XBP1 pathway, and promotes cross-linking of extracellular matrix proteins. LOXL2 is involved in EMT, tumor progression, angiogenesis regulation, and chondrocyte differentiation. LOXL2 Protein, Human (HEK293, His) is the recombinant human-derived LOXL2 protein, expressed by HEK293 , with C-His labeled tag. The total length of LOXL2 Protein, Human (HEK293, His) is 774 a.a., with molecular weight of ~110 kDa.
  • HY-P701534
    BACH2 Protein, Human (Sf9, His, Strep)

    BACH2; Transcription regulator protein BACH2; BTB and CNC homolog 2

    		 Human Sf9 insect cells
    BACH2 is a multifunctional transcriptional regulator that acts as both a repressor and an activator and recognizes Maf recognition elements (MAREs) to coordinate the transcriptional regulation of MAFKs. During oxidative stress, BACH2 induces apoptosis by inhibiting HMOX1. BACH2 Protein, Human (Sf9, His, Strep) is the recombinant human-derived BACH2 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of BACH2 Protein, Human (Sf9, His, Strep) is 840 a.a., .
  • HY-P70096
    COQ7 Protein, Human (HEK293, His)

    rHu5-demethoxyubiquinone hydroxylase, mitochondrial/COQ7, His; Ubiquinone Biosynthesis Protein COQ7 homolog; Coenzyme Q Biosynthesis Protein 7 homolog; Timing Protein Clk-1 homolog; COQ7

    		 Human HEK293
    The COQ7 protein is a key enzyme in lipid A biosynthesis and catalyzes a key hydrolysis step involving UDP-3-O-myristoyl-N-acetylglucosamine. This activity leads to the formation of UDP-3-O-myristoylglucosamine and acetate, which is a decisive point in lipid A synthesis. COQ7 Protein, Human (HEK293, His) is the recombinant human-derived COQ7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of COQ7 Protein, Human (HEK293, His) is 181 a.a., with molecular weight of 19-22 kDa.
  • HY-P70052
    CXADR Protein, Mouse (HEK293, Fc)

    rMuCoxsackievirus and adenovirus receptor homolog/CXADR, Fc; Coxsackievirus and adenovirus receptor homolog; CAR; Cxadr; CVB3 BP

    		 Mouse HEK293
    CXADR protein is a key component of the epithelial apical junction complex, which maintains the integrity of tight junctions and enables leukocyte migration through adhesive interactions with JAML. This interaction activates γ-δ T cells and promotes tissue repair through cell signaling involving PI3 kinase and MAP kinase. CXADR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CXADR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CXADR Protein, Mouse (HEK293, Fc) is 218 a.a., with molecular weight of 50-70 kDa.
  • HY-P73636
    SMAD3 Protein, Human/Mouse/Rat (sf9, His-GST)

    Mothers against decapentaplegic homolog 3; mMad3; Smad3; Madh3

    		 Rat Sf9 insect cells
    The SMAD3 protein is an R-SMAD that acts as an intracellular signal transducer activated by TGF-β and activin type 1 receptor kinase. It binds TRE elements and regulates TGF-β target genes. SMAD3 Protein, Human/Mouse/Rat (sf9, His-GST) is the recombinant rat-derived SMAD3 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of SMAD3 Protein, Human/Mouse/Rat (sf9, His-GST) is 425 a.a., with molecular weight of ~75.9 kDa.
  • HY-P74138
    Frizzled-5 Protein, Human (HEK293, His)

    C2orf31; Frizzled homolog 5 (Drosophila); Frizzled-5; FZ-5; FZD5

    		 Human HEK293
    Frizzled-5 protein is a receptor for Wnt proteins (WNT2, WNT10B, WNT5A), which can activate WNT7A and promote the formation of synapses in neurons. It participates in the canonical Wnt/β-catenin pathway, activating disheveled proteins, inhibiting GSK-3 kinase, and triggering Wnt target genes. Frizzled-5 Protein, Human (HEK293, His) is the recombinant human-derived Frizzled-5 protein, expressed by HEK293 , with C-His labeled tag. The total length of Frizzled-5 Protein, Human (HEK293, His) is 141 a.a., with molecular weight of 25-30 kDa.
  • HY-P74139
    Frizzled-5 Protein, Human (HEK293, Fc)

    C2orf31; Frizzled homolog 5 (Drosophila); Frizzled-5; FZ-5; FZD5

    		 Human HEK293
    Frizzled-5 protein is a receptor for Wnt proteins (WNT2, WNT10B, WNT5A), which can activate WNT7A and promote the formation of synapses in neurons. It participates in the canonical Wnt/β-catenin pathway, activating disheveled proteins, inhibiting GSK-3 kinase, and triggering Wnt target genes. Frizzled-5 Protein, Human (HEK293, Fc) is the recombinant human-derived Frizzled-5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Frizzled-5 Protein, Human (HEK293, Fc) is 141 a.a., with molecular weight of ~42.7 kDa.
  • HY-P702618
    EZH2 Protein, Human (P.pastoris, His)

    ENX-1; Enhancer of zeste homolog 2; Lysine N-methyltransferase 6

    		 Human P. pastoris
  • HY-P71149
    NOV/CCN3 Protein, Mouse (HEK293, His)

    Protein NOV homolog; NovH; CCN family member 3; Nephroblastoma-overexpressed gene protein homolog; Nov

    		 Mouse HEK293
    The NOV/CCN3 protein is an early player that coordinates diverse cellular processes such as proliferation, adhesion, migration, differentiation, and survival. By interacting with membrane receptors such as integrins or NOTCH1, it regulates hematopoietic stem cells and inhibits myogenic differentiation while affecting the expression of cell cycle regulators. NOV/CCN3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived NOV/CCN3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of NOV/CCN3 Protein, Mouse (HEK293, His) is 329 a.a., with molecular weight of ~50.0 kDa.
  • HY-P76840
    PRAT4B/CNPY4 Protein, Mouse (HEK293, His)

    Protein canopy homolog 4; Protein associated with Tlr4; Prat4b

    		 Mouse HEK293
    PRAT4B/CNPY4 Protein is pivotal in regulating TLR4 cell surface expression, actively orchestrating cellular processes. Direct interaction with TLR4 underscores its crucial involvement, emphasizing significance in steering molecular pathways. This dynamic interplay highlights PRAT4B/CNPY4's essential contribution to finely tuning cellular responses, establishing it as a key regulatory factor in immune-related signaling cascades. PRAT4B/CNPY4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PRAT4B/CNPY4 protein, expressed by HEK293 , with C-His labeled tag. The total length of PRAT4B/CNPY4 Protein, Mouse (HEK293, His) is 218 a.a., with molecular weight of ~26.5 KDa.

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