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Results for "

homology

" in MedChemExpress (MCE) Product Catalog:

By Targets:	SHP2 (1) Adrenergic Receptor (1) Akt (4) Antibiotic (1) Apoptosis (9) ATM/ATR (2) Bcr-Abl (1) Btk (1) CRISPR/Cas9 (3) DNA-PK (1) DNA/RNA Synthesis (2) Fluorescent Dye (1) Gap Junction Protein (1) GCGR (1) Integrin (1) JAK (3) Neuropeptide Y Receptor (1) Phosphatase (2) Ras (2) Ser/Thr Protease (2) Src (2) STAT (3)
By Research Areas:	Cancer (24) Cardiovascular Disease (1) Endocrinology (3) Infection (1) Inflammation/Immunology (5) Metabolic Disease (1) Neurological Disease (7)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Targets Recommended: SHP2

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15369

FPA-124	Akt Apoptosis	Cancer
FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC₅₀ of 0.1 μM. FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis .

HY-14722A

NVP-BSK805 dihydrochloride 1 Publications Verification	JAK	Cancer
NVP-BSK805 dihydrochloride is an ATP-competitive JAK2 inhibitor, with IC₅₀s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively .

HY-14722

NVP-BSK805 1 Publications Verification	JAK	Cancer
NVP-BSK805 is an ATP-competitive JAK2 inhibitor, with IC₅₀s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively .

HY-110013

Terreic acid	Btk Antibiotic	Infection Inflammation/Immunology
Terreic acid, a quinone epoxide antibiotic, acts as an effective Btk inhibitor. Terreic acid blocks the interaction between PKC and the pleckstrin homology domain of Btk. Terreic acid inhibits the binding of GST-BtkPH to PKC in lysates of HMC-1 human mast cells with an IC₅₀ of approximately 100 μM .

HY-14722C

NVP-BSK805 trihydrochloride	JAK	Cancer
NVP-BSK805 trihydrochloride trihydrochloride is an ATP-competitive JAK2 inhibitor, with IC₅₀s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively .

HY-19820A

NSC45586 sodium	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 sodium is an inhibitor of *pleckstrin homology* domain and leucine-rich repeat protein phosphatase (PHLPP)**. NSC45586 sodium targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 sodium can activate AKT in neurons .

HY-19820

NSC45586	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 is an inhibitor of *pleckstrin homology* domain and leucine-rich repeat protein phosphatase (PHLPP)**. NSC45586 targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons .

HY-N2521

Tetramethylcurcumin FLLL31	STAT Apoptosis	Inflammation/Immunology Cancer
Tetramethylcurcumin (FLLL31), derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects .

HY-19977

YU238259

DNA-PK Cancer

YU238259 is an inhibitor of homology-dependent DNA repair (HDR), used for cancer research.

YU238259	DNA-PK	Cancer
YU238259 is an inhibitor of homology-dependent DNA repair (HDR), used for cancer research.

HY-12063

PHT-427 1 Publications Verification	Akt Apoptosis	Cancer
PHT-247 is an inhibitor of the pleckstrin homology (PH) domain of Akt, and it is also an inhibitor of PDPK1 with K_is of 2.7 µM and 5.2 µM and for Akt and PDPK1, respectively.

HY-P3279

EPQpYEEIPIYL 1 Publications Verification	Src	Cancer
EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains .

HY-P0139

Gap 27 5 Publications Verification	Gap Junction Protein	Cardiovascular Disease
Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment .

HY-117693

Mirin 1 Publications Verification	ATM/ATR	Cancer
Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor. Mirin prevents MRN-dependent activation of ATM (IC₅₀=12 μM) without affecting ATM protein kinase activity, and it inhibits Mre11-associated exonuclease activity. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells. Mirin prevents ATM activation in response to DNA double-strand breaks (DSBs) and blocks homology-directed repair (HDR) in mammalian cells .

HY-19334

L755507 1 Publications Verification	Adrenergic Receptor CRISPR/Cas9	Endocrinology Cancer
L755507 is a potent, selective agonist of β₃-AR with an IC₅₀ of 35 nM. L755507 enhances the homology-directed repair (HDR)-mediated genome editing in CRISPR/Cas9 nickase system .

HY-P1816

Fibronectin CS1 Peptide	Integrin	Cancer
The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models .

HY-N12613

Sydowimide A	Phosphatase	Inflammation/Immunology
Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC₅₀ values of 1.5, 2.4 and 18.83 μM, respectively .

HY-153992

STAT6-IN-3	STAT	Inflammation/Immunology
STAT6-IN-3 (Compound 18a) is a STAT6 inhibitor (IC₅₀= 44 nM). STAT6-IN-3 targets the Src Homology 2 (SH2) domain of STAT6. STAT6-IN-3 can be used for research of inflammation such as asthma .

HY-115739

RTIL 13	Ras	Neurological Disease Cancer
RTIL 13 is a potent inhibitor of dynamin GTPase, with an IC₅₀ of 2.3 µM for dynamin I GTPase. RTIL 13 also targets *pleckstrin homology* lipid binding domain. RTIL 13 can inhibit receptor-mediated and synaptic vesicle endocytosis, with IC₅₀**s of 9.3 μM and 7.1 μM, respectively .

HY-P3463

Beinaglutide GLP-1 (human)	GCGR	Metabolic Disease Inflammation/Immunology
Beinaglutide is a human GLP-1 polypeptide that shares almost 100% homology with human GLP-1 (7–36). Beinaglutide displays does-dependent effects in glycemic control, inhibiting food intake and gastric empty and promoting weight loss. Beinaglutide has the potential for the research of overweight/obesity and nonalcoholic steatohepatitis (NASH) .

HY-148384

UHMCP1	Others	Cancer
UHMCP1 is a chemical probe of *U2AF homology* motifs (UHM) with a K_d** of 79 μM. UHMCP1 prevents the SF3b155/U2AF65 interaction, impacts RNA splicing and cell viability. UHMCP1 has potential anticancer properties .

HY-157507

JC-010a

SHP2 Apoptosis Cancer

JC-010a is a selective SHP2 allosteric inhibitor. JC-010a inhibits cancer cells proliferation. JC-010a can be used for the research of cancer .

JC-010a	SHP2 Apoptosis	Cancer
JC-010a is a selective SHP2 allosteric inhibitor. JC-010a inhibits cancer cells proliferation. JC-010a can be used for the research of cancer .

HY-128590

PHT-7.3 1 Publications Verification	Ras	Cancer
PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (K_d=4.7 μM). PHT-7.3 inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling. PHT-7.3 has antitumor activity .

HY-50868

Bafetinib 5+ Cited Publications INNO-406; NS-187	Bcr-Abl Src Apoptosis	Cancer
Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph ⁺ leukemia cells. Bafetinib has antitumor activity .

HY-107845

SCR7 pyrazine Maximum Cited Publications 10 Publications Verification	CRISPR/Cas9 DNA/RNA Synthesis Apoptosis	Cancer
SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine is also a CRISPR/Cas9 enhancer which increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity .

HY-P3677

Neuropeptide Y (2-36) (porcine)	Neuropeptide Y Receptor	Neurological Disease
Neuropeptide Y (2-36) (porcine) is a porcine-derived neuropeptide with 97.14% homology to rat/human origin. Neuropeptide Y (2-36) (porcine) is also a rat neuropeptide receptor agonist, with EC₅₀ values of 1.2, 1.6 and 3.4 nM for receptor of Y5, Y2 and Y1 respectively. Neuropeptide Y (2-36) (porcine) can be used in studies related to obesity and eating disorders .

HY-19959

(Z)-Mirin 5 Publications Verification	ATM/ATR Apoptosis	Cancer
(Z)-Mirin is an MRN (Mre11-Rad50-Nbs1) inhibitor. (Z)-Mirin prevents MRN-dependent activation of ATM without affecting ATM protein kinase activity. (Z)-Mirin inhibits Mre11-associated exonuclease activity. (Z)-Mirin increases apoptosis, triggers a G2/M checkpoint and strongly inhibits homology-directed repair (HDR) .

HY-12742

SCR7	DNA/RNA Synthesis CRISPR/Cas9 Apoptosis	Cancer
SCR7 is an unstable form that can be autocyclized into a stable form SCR7 pyrazine. SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine is also a CRISPR/Cas9 enhancer which increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity .

HY-D2204

SHP1-IN-1	Phosphatase Fluorescent Dye	Cancer
SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe ³⁺ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM) .

HY-151411

RUNX1/ETO tetramerization-IN-1	Others	Cancer
RUNX1/ETO tetramerization-IN-1 is a small-molecule inhibitor of RUNX1/ETO tetramerization, exhibits anti-leukemic effect. RUNX1/ETO tetramerization-IN-1 specifically targets to NHR2 of RUNX1/ETO (EC₅₀=0.25 μM), restores gene expression down-regulated by RUNX1/ETO. RUNX1/ETO tetramerization-IN-1 inhibits the proliferation of RUNX1/ETO-depending SKNO-1 cells, and reduces the RUNX1/ETO-related tumor growth in a mouse model .

HY-151577

STAT3-SH2 domain inhibitor 1	STAT Apoptosis	Cancer
STAT3-SH2 domain inhibitor 1 is a potent *Src Homology* 2 (SH2) Domain of STAT3 (STAT3-SH2 domain) inhibitor with a K_d value of 1.57 μM. STAT3-SH2 domain inhibitor 1 inhibits STAT3 signaling transduction and transcriptional activation. STAT3-SH2 domain inhibitor 1 induces apoptosis** in gastric cancer cells. STAT3-SH2 domain inhibitor 1 can be used in research of cancer .

Cat. No.	Product Name

HY-L055

*Medicine Food Homology* Compound Library**	1714 compounds
Medicine Food Homology (MFH) means that some food themselves are medicines and there is no absolute boundary between them. MFH theory combines the function of food and medicine together scientifically and MFH materials can be used both for food and medicine. Besides nutritional value, MFH materials also have the functions in the prevention and treatment of disease and many other healthcare effects. Food as medicines has many benefits because of their safety while taking drugs will bring inevitable side effect to people. In order to ensure the safe use of functional food, National Health Commission of People's Republic of China made specific provisions on MFH items. More than 100 kinds of widely used MFH materials have been released. Based on MFH items released by National Health Commission, PRC, MCE carefully designs a unique collection of 1714 Medicine Food Homology Compounds with high safety that can be used for high throughput and high content screening for drug discovery.

Medicine Food Homology Compound Library

1714 compounds

Medicine Food Homology (MFH) means that some food themselves are medicines and there is no absolute boundary between them. MFH theory combines the function of food and medicine together scientifically and MFH materials can be used both for food and medicine. Besides nutritional value, MFH materials also have the functions in the prevention and treatment of disease and many other healthcare effects. Food as medicines has many benefits because of their safety while taking drugs will bring inevitable side effect to people. In order to ensure the safe use of functional food, National Health Commission of People's Republic of China made specific provisions on MFH items. More than 100 kinds of widely used MFH materials have been released.

Based on MFH items released by National Health Commission, PRC, MCE carefully designs a unique collection of 1714 Medicine Food Homology Compounds with high safety that can be used for high throughput and high content screening for drug discovery.

Cat. No.	Product Name	Type

HY-D2204

SHP1-IN-1	Fluorescent Dyes/Probes
SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe ³⁺ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM) .

Cat. No.	Product Name	Target	Research Area

HY-P1183

Locustatachykinin I	Peptides	Neurological Disease Endocrinology
Locustatachykinin I is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I is also a substrate for a deamidase .

HY-P3279

EPQpYEEIPIYL 1 Publications Verification	Src	Cancer
EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains .

HY-P0139

Gap 27 5 Publications Verification	Gap Junction Protein	Cardiovascular Disease
Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment .

HY-P3633

Locustatachykinin II Lom-TK II	Peptides	Neurological Disease
Locustatachykinin II (Lom-TK II) is an insect neuropeptide with homology to peptides of the vertebrate tachykinin family. Locustatachykinin II can be used for the research of insect endocrine .

HY-P1183A

Locustatachykinin I TFA	Peptides	Neurological Disease Endocrinology
Locustatachykinin I TFA is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I TFA exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I TFA is also a substrate for a deamidase .

HY-P1816

Fibronectin CS1 Peptide	Integrin	Cancer
The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models .

HY-P3463

Beinaglutide GLP-1 (human)	GCGR	Metabolic Disease Inflammation/Immunology
Beinaglutide is a human GLP-1 polypeptide that shares almost 100% homology with human GLP-1 (7–36). Beinaglutide displays does-dependent effects in glycemic control, inhibiting food intake and gastric empty and promoting weight loss. Beinaglutide has the potential for the research of overweight/obesity and nonalcoholic steatohepatitis (NASH) .

HY-P3677

Neuropeptide Y (2-36) (porcine)	Neuropeptide Y Receptor	Neurological Disease
Neuropeptide Y (2-36) (porcine) is a porcine-derived neuropeptide with 97.14% homology to rat/human origin. Neuropeptide Y (2-36) (porcine) is also a rat neuropeptide receptor agonist, with EC₅₀ values of 1.2, 1.6 and 3.4 nM for receptor of Y5, Y2 and Y1 respectively. Neuropeptide Y (2-36) (porcine) can be used in studies related to obesity and eating disorders .

HY-P5387

Connexin mimetic peptide 40,37GAP26	Peptides	Others
Connexin mimetic peptide 40,37GAP26 is a biological active peptide. (This peptide corresponds to the GAP26 domain of the extracellular loop of the major vascular connexins (Cx37, Cx40), designated as 37, 40Gap 26 according to Cx homology. It was used to investigate the role of gap junctions in the spread of endothelial hyperpolarizations evoked by cyclopiazonic acid (CPA) through the wall of the rodent iliac artery. The gap junction plaques constructed from Cx37 and Cx40 were abundant in the endothelium. This peptide provides inhibitory effects against subintimal hyperpolarization.)

Tetramethylcurcumin FLLL31	other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields Inflammation/Immunology	STAT Apoptosis
Tetramethylcurcumin (FLLL31), derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects .

Species:	Virus (3) Human (7) Mouse (2) Rat (2)
Tag:	His (9) Tag Free (3) Fc (2)
Source:	HEK293 (8) Sf9 insect cells (3) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P75814

	*Glycoprotein/G Protein, HRSV (95% Homology, HEK293, His)* Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G / RSV-G Protein (95% homology)	Virus	HEK293
	A glycoprotein/G protein critical in the immune response forms the interleukin-31 receptor with OSMR. This receptor activates STAT3 and, to a lesser extent, STAT1 and STAT5, playing a critical role in skin immunity and mediating IL31-induced itch, possibly involving TRPA1 and TRPV1. Glycoprotein/G Protein, HRSV (95% Homology, HEK293, His) is the recombinant Virus-derived Glycoprotein/G protein, expressed by HEK293 , with C-His labeled tag. The total length of Glycoprotein/G Protein, HRSV (95% Homology, HEK293, His) is 232 a.a., with molecular weight of ~50-100 kDa.

HY-P75813

	*glycoprotein/G Protein, HRSV (93% Homology, HEK293, His)* Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G / RSV-G Protein (93% homology)	Virus	HEK293
	The glycoprotein/G Protein, crucial in the immune response, forms the interleukin-31 receptor with OSMR. This receptor activates STAT3, and to a lesser extent, STAT1 and STAT5, playing a vital role in skin immunity and mediating IL31-induced itch, potentially involving TRPA1 and TRPV1. It positively regulates myeloid progenitor cell numbers and cycling status in the bone marrow, enhancing survival. Acting in viral infection, the glycoprotein/G Protein attaches the virion to the host cell membrane, interacts with heparan sulfate, modulates the immune response through CX3CR1, and aids in escaping antibody-dependent restriction by acting as an antigen decoy. glycoprotein/G Protein, HRSV (93% Homology, HEK293, His) is the recombinant Virus-derived glycoprotein/G protein, expressed by HEK293, with C-His labeled tag. The total length of glycoprotein/G Protein, HRSV (93% Homology, HEK293, His) is 232 a.a., with molecular weight of 60-90 kDa.

HY-P75812

	glycoprotein/G Protein, HRSV (sf9, His) Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G / RSV-G Protein (93% homology)	Virus	Sf9 insect cells
	The glycoprotein/G Protein, crucial in the immune response, forms the interleukin-31 receptor with OSMR. This receptor activates STAT3, and to a lesser extent, STAT1 and STAT5, playing a vital role in skin immunity and mediating IL31-induced itch, potentially involving TRPA1 and TRPV1. It positively regulates myeloid progenitor cell numbers and cycling status in the bone marrow, enhancing survival. Acting in viral infection, the glycoprotein/G Protein attaches the virion to the host cell membrane, interacts with heparan sulfate, modulates the immune response through CX3CR1, and aids in escaping antibody-dependent restriction by acting as an antigen decoy. glycoprotein/G Protein, HRSV (sf9, His) is the recombinant Virus-derived glycoprotein/G protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of glycoprotein/G Protein, HRSV (sf9, His) is 232 a.a., with molecular weight of 40-55 kDa.

HY-P75744

	EphA6 Protein, Mouse (HEK293, Fc) Ephrin type-A receptor 6; EPH homology kinase 2; EHK-2; Epha6	Mouse	HEK293
	EphA6 Protein, a receptor tyrosine kinase, engages in promiscuous binding with GPI-anchored ephrin-A ligands, facilitating contact-dependent bidirectional signaling. EphA6 mediates intricate signaling exchanges between cells, playing a crucial role in diverse cellular processes through both forward and reverse signaling pathways. EphA6 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EphA6 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EphA6 Protein, Mouse (HEK293, Fc) is 546 a.a., with molecular weight of ~110 kDa.

HY-P75745

	EphA6 Protein, Mouse (HEK293, His) Ephrin type-A receptor 6; EPH homology kinase 2; EHK-2; Epha6	Mouse	HEK293
	EphA6 Protein, a receptor tyrosine kinase, engages in promiscuous binding with GPI-anchored ephrin-A ligands, facilitating contact-dependent bidirectional signaling. EphA6 mediates intricate signaling exchanges between cells, playing a crucial role in diverse cellular processes through both forward and reverse signaling pathways. EphA6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphA6 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphA6 Protein, Mouse (HEK293, His) is 524 a.a., with molecular weight of ~65-70 kDa.

HY-P702708

	EphA7 Protein, Human (sf9) EPHA7; EPH receptor A7; EphA7; ephrin type-A receptor 7; Hek11; EK11; EHK-3; EPH-like kinase 11; EPH homology kinase 3; Eph homology kinase-3; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3; EHK3; HEK11	Human	Sf9 insect cells

HY-P76319

	EphA7 Protein, Rat (HEK293, Fc) Ephrin Type-A Receptor 7; EPH homology Kinase 3; EHK-3; EPH-Like Kinase 11; EK11; EPHA7; HEK11	Rat	HEK293
	The EphA7 protein is a receptor tyrosine kinase that participates in bidirectional signaling with GPI-anchored ephrin A ligands (such as EFNA5). It affects brain development by regulating cell-cell adhesion and repulsion. EphA7 Protein, Rat (HEK293, Fc) is the recombinant rat-derived EphA7 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EphA7 Protein, Rat (HEK293, Fc) is 539 a.a., with molecular weight of ~58.9 KDa.

HY-P76320

	EphA7 Protein, Rat (HEK293, His) Ephrin Type-A Receptor 7; EPH homology Kinase 3; EHK-3; EPH-Like Kinase 11; EK11; EPHA7; HEK11	Rat	HEK293
	The EphA7 protein is a receptor tyrosine kinase that participates in bidirectional signaling with GPI-anchored ephrin A ligands (such as EFNA5). It affects brain development by regulating cell-cell adhesion and repulsion. EphA7 Protein, Rat (HEK293, His) is the recombinant rat-derived EphA7 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphA7 Protein, Rat (HEK293, His) is 512 a.a., with molecular weight of ~65-72 KDa.

HY-P70842

	EphA7 Protein, Human (HEK293, His) Ephrin Type-A Receptor 7; EPH homology Kinase 3; EHK-3; EPH-Like Kinase 11; EK11; hEK11; EPHA7; EHK3; HEK11	Human	HEK293
	The EphA7 protein is a receptor tyrosine kinase that promiscuously binds to the GPI-anchored ephrin-A ligand to initiate bidirectional signaling. It participates in forward and reverse signaling pathways, uses EFNA5 as a functional ligand, regulates brain development and affects cell adhesion and repulsion. EphA7 Protein, Human (HEK293, His) is the recombinant human-derived EphA7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EphA7 Protein, Human (HEK293, His) is 529 a.a., with molecular weight of ~72.0 kDa.

HY-P71340

	STUB1 Protein, Human E3 Ubiquitin-Protein Ligase CHIP; Antigen NY-CO-7; CLL-Associated Antigen KW-8; Carboxy Terminus of Hsp70-Interacting Protein; STIP1 homology and U Box-Containing Protein 1; STUB1; CHIP	Human	E. coli
	STUB1 protein is an E3 ubiquitin protein ligase that cooperates with ATXN3 to regulate ubiquitin chain length on substrates and prevent chain extension. It ubiquitinates NOS1 through Hsp70/Hsp40 and regulates chaperone complexes (Hsp70, Hsc70, Hsp90). STUB1 Protein, Human is the recombinant human-derived STUB1 protein, expressed by E. coli , with tag free. The total length of STUB1 Protein, Human is 303 a.a., with molecular weight of ~33.0 kDa.

HY-P71202

	PHLDA2 Protein, Human (His) Pleckstrin homology-Like Domain Family A Member 2; Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate Gene C Protein; Imprinted in Placenta and Liver Protein; Tumor-Suppressing STF cDNA 3 Protein; Tumor-Suppressing Subchromosomal Transferable Fragment	Human	E. coli
	PHLDA2 protein regulates placenta growth, potentially through its PH domain, which competes with other PH domain-containing proteins, hindering their binding to membrane lipids. PHLDA2 Protein, Human (His) is the recombinant human-derived PHLDA2 protein, expressed by E. coli , with C-6*His labeled tag. The total length of PHLDA2 Protein, Human (His) is 152 a.a., with molecular weight of 14-25 kDa.

HY-P70095

	DCBLD2 Protein, Human (HEK293, His) rHuDiscoidin, CUB and LCCL domain-containing protein 2/ DCBLD2, His; Discoidin; CUB and LCCL domain-containing protein 2; DCBLD2; CUB; LCCL and coagulation factor V/VIII-homology domains protein 1; Endothelial and smooth muscle cell-derived neuropilin-like protein; DCBLD2; CLCP1; ESDN;	Human	HEK293
	DCBLD2 Protein is a novel platelet membrane receptor that recruits TRAF6 through EGFR phosphorylation and stimulates AKT to promote tumorigenesis. The DCBLD2 Protein has multiple functions during development as well as in vascular and tumor biology, such as influencing cell proliferation and tumorigenesis. DCBLD2 Protein, Human (HEK293, His) is the recombinant human-derived DCBLD2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of DCBLD2 Protein, Human (HEK293, His) is 462 a.a., with molecular weight of 80-110 kDa.

HY-P70997

	SUMO1 Protein, Human (His) Small Ubiquitin-Related Modifier 1; SUMO-1; GAP-Modifying Protein 1; GMP1; SMT3 Homolog 3; Sentrin; Ubiquitin-homology Domain Protein PIC1; Ubiquitin-Like Protein SMT3C; Smt3C; Ubiquitin-Like Protein UBL1; SUMO1; SMT3C; SMT3H3; UBL1	Human	E. coli
	SUMO1 Protein is a member of the SUMO (small ubiquitin-like modifier) protein family. SUMO1 binds to target proteins as part of a post-translational modification system. It is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 also regulates the function of several proteins via non-covalent interactions. SUMO1 Protein, Human (His) is the recombinant human-derived SUMO1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SUMO1 Protein, Human (His) is 101 a.a., with molecular weight of 17-19 kDa.

HY-P702705

	TIE-2 Protein, Human (Biotinylated, sf9) TEK; TEK tyrosine kinase, endothelial; venous malformations, multiple cutaneous and mucosal , VMCM; angiopoietin-1 receptor; CD202b; TIE 2; TIE2; VMCM1; hTIE2; p140 TEK; soluble TIE2 variant 1; soluble TIE2 variant 2; endothelial tyrosine kinase; tyrosine-protein kinase receptor TEK; tunica interna endothelial cell kinase; tyrosine-protein kinase receptor TIE-2; tyrosine kinase with Ig and EGF homology domains-2; VMCM; TIE-2; CD202B	Human	Sf9 insect cells

Cat. No.	Product Name	Application	Reactivity

HY-P82537

BLNK Antibody (YA2282) BLNK; BASH; SLP65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa	WB, IP	Human, Mouse, Rat

HY-P82649

SHC Antibody (YA2394) SHC1; SHC; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

HY-P83492

MLK3 Antibody (YA3237) MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase	WB, ICC/IF	Human

HY-P83327

WAVE 2 Antibody (YA3072) WASF2; WAVE2; Wiskott-Aldrich syndrome protein family member 2; WASP family protein member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2	WB, IHC-P	Human, Mouse, Rat

HY-P80905

SUMO1 Antibody (YA047) SUMO1; SMT3C; SMT3H3; UBL1; OK/SW-cl.43; Small ubiquitin-related modifier 1; SUMO-1; GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Smt3C; Ubiquitin-like protein	WB, IHC-P	Human, Mouse, Rat
SUMO1 Antibody (YA047) is a non-conjugated and Rabbit origined monoclonal antibody, targeting to SUMO1. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P81233

DDIT3 Antibody GADD153; CHOP; Growth arrest and DNA damage-inducible 153; C/EBP homologous protein; C/EBP homology Protein; CEBPZ; CHOP10; DDIT 3; DNA Damage Inducible Transcript 3; GADD 153; Growth Arrest and DNA Damage Inducible Protein 153; Growth arrest and DNA damage inducible protein GADD153; MGC4154; DDIT3_HUMAN.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Mouse, Rat(predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep)
DDIT3 Antibody is an unconjugated, approximately 19 kDa, rabbit-derived, anti-DDIT3 polyclonal antibody. DDIT3 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: dog, pig, cow, horse, rabbit, sheep background without labeling.

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