Search Result

Results for "

hypolipidemic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (2) Amylases (1) Apoptosis (1) ATP Citrate Lyase (2) Bacterial (1) COX (1) Dipeptidyl Peptidase (1) Drug Metabolite (3) Endogenous Metabolite (2) ERK (1) Glucosidase (1) Isotope-Labeled Compounds (2) NF-κB (1) PPAR (9)
By Research Areas:	Cancer (1) Cardiovascular Disease (11) Inflammation/Immunology (4) Metabolic Disease (19) Neurological Disease (3)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-137318

BM 15766 sulfate	Others	Metabolic Disease
BM 15766 sulfate is an inhibitor of 7-dehydrocholesterol δ7-reductase and reduces plasma cholesterol levels. BM 15766 sulfate is a hypolipidemic agent .

HY-34781

4'-Trifluoromethyl-2-biphenyl carboxylic acid

Others Cardiovascular Disease Metabolic Disease

4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent .

4'-Trifluoromethyl-2-biphenyl carboxylic acid	Others	Cardiovascular Disease Metabolic Disease
4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent .

HY-121776

Nicomol	Others	Cardiovascular Disease
Nicomol is an orally active hypolipidemic agent that can increase the high density lipoprotein cholesterol (HDL-C) level. Nicomol inhibits the rapid rise of plasma free fatty acids .

HY-N1214S

Squalene-d6 Super Squalene-d₆; trans-Squalene-d₆; AddaVax-d₆	Isotope-Labeled Compounds	Others
Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-121755

Tibric acid CP 18524	Others	Metabolic Disease
Tibric acid (CP 18524) has similar effects to those of hypolipidemic agents. Tibric acid has orally active triglyceride-lowering effects. Tibric acid can be used for research of hypertriglyceridemia .

HY-119964

Cetaben	Others	Cardiovascular Disease
Cetaben is a PPARα-independent peroxisome proliferator. Cetaben is a non-fibrate hypolipidemic agent and potently reduces the concentration of cholesterol and triglycerides .

HY-N6642

Ankaflavin	PPAR Apoptosis	Inflammation/Immunology Cancer
Ankaflavin, isolated from Monascus-Fermented red rice, is an orally active PPARγ agonist. Ankaflavin exhibits selective cytotoxic effect and induces cell death through apoptosis on cancer cells. Ankaflavin has anti-inflammatory, anti-cancer, antiatherosclerotic, and hypolipidemic effects .

HY-116699

CP-868388 free base	PPAR	Neurological Disease Metabolic Disease Inflammation/Immunology
CP-868388 free base is a potent, selective and orally active PPARα agonist with a K_i value of 10.8 nM. CP-868388 free base has little or no affinity for PPARβ (K_i of 3.47 μM) and PPARγ. CP-868388 free base has hypolipidemic and anti-inflammatory actions .

HY-147246

Berberine ursodeoxycholate HTD1801; BUDCA	Others	Metabolic Disease
Berberine ursodeoxycholate (HTD1801), an ionic salt of Berberine and Ursodeoxycholic acid, is an orally active and potent *hypolipidemic* agent. Berberine ursodeoxycholate shows significantly great reduction in liver fat content. Berberine ursodeoxycholate has a broad spectrum of metabolic activity. Berberine ursodeoxycholate can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes .

HY-N0652

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside 1 Publications Verification 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside	ERK NF-κB	Cardiovascular Disease Neurological Disease
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions .

HY-115914

Lipid-lowering agent-1	Others	Others
Lipid-lowering agent-1 is a potent lipid-lowering agent. Lipid-lowering agent-1 has significant pharmacological effects on the inhibition of low-density lipoprotein cholesterol (LDLC) and promotion of high-density lipoprotein cholesterol (HDLC) production. Lipid-lowering agent-1 shows potent hypolipidemic effect in high-fat diet rats .

HY-100144

Pirozadil

Others Metabolic Disease

Pirozadil is a hypolipidemic agent.
HY-19030

TA-1801

Others Metabolic Disease

TA-1801 is a hypolipidemic agent.
HY-100334

Pirinixil

BR-931
Others Metabolic Disease

Pirinixil is a hypolipidemic agent of low toxicity.
HY-100258

Y-9738

Others Cardiovascular Disease

Y-9738 is a hypolipidemic agent.
HY-N8206

Chrysophanol tetraglucoside

Bacterial Metabolic Disease Inflammation/Immunology

Chrysophanol tetraglucoside possesses anti-hypolipidemic and antibacterial activities .
HY-113873

10-Thiastearic acid

Others Metabolic Disease

10-Thiastearic acid inhibits desaturation of? stearate to oleate. 10-Thiastearic acid has hypolipidemic effect .

Pirozadil	Others	Metabolic Disease
Pirozadil is a hypolipidemic agent.

TA-1801	Others	Metabolic Disease
TA-1801 is a hypolipidemic agent.

Pirinixil BR-931	Others	Metabolic Disease
Pirinixil is a hypolipidemic agent of low toxicity.

Y-9738	Others	Cardiovascular Disease
Y-9738 is a hypolipidemic agent.

Chrysophanol tetraglucoside	Bacterial	Metabolic Disease Inflammation/Immunology
Chrysophanol tetraglucoside possesses anti-hypolipidemic and antibacterial activities .

10-Thiastearic acid	Others	Metabolic Disease
10-Thiastearic acid inhibits desaturation of? stearate to oleate. 10-Thiastearic acid has hypolipidemic effect .

HY-N9725

16-Hydroxycleroda-3,13-dien-15,16-olide 16ξ-Hydroxycleroda-3,13-dien-15,16-olide	Dipeptidyl Peptidase	Metabolic Disease
16-Hydroxycleroda-3,13-dien-15,16-olide (16ξ-Hydroxycleroda-3,13-dien-15,16-olide; HCD), a clerodane diterpene, is a potent serine protease dipeptidyl peptidase 4 (DPP-4) inhibitor. 16-Hydroxycleroda-3,13-dien-15,16-olide down-regulates LPS-induced ERK phosphorylation in myocyte but blocks GLP-1 induced PKA expression. 16-Hydroxycleroda-3,13-dien-15,16-olide exhibits hypolipidemic, hepatoprotective, hypoglycemic efficacy .

HY-A0127

Etofibrate	Others	Metabolic Disease
Etofibrate is the ethandiol-1,2 diester of the nicotinic and clofibric acids. Etofibrate has been shown to be a potent hypolipidemic agent in animal and human.

HY-N1214

Squalene Super Squalene; trans-Squalene; AddaVax
Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-B1415

Clofibric acid Chlorofibrinic acid	PPAR Drug Metabolite	Others
Clofibric acid (Chlorofibrinic acid), the pharmaceutically active metabolite of lipid regulators Clofibrate, Etofibrate and Etofyllinclofibrate, is a PPARα agonist which exhibits hypolipidemic effects. Clofibric acid also is an herbicide .

HY-105008

Secoisolariciresinol diglucoside 4 Publications Verification (S,S)-SDG; (S,S)-LGM2605	Others	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects .

HY-117549

Ibrolipim NO-1886	Others	Cardiovascular Disease
Ibrolipim (NO-1886) is an orally active lipoprotein lipase (LPL)-promoting agent. Ibrolipim decreases plasma triglycerides, increases high-density lipoprotein cholesterol levels. Ibrolipim has renoprotective and hypolipidemic effects .

HY-N7729

Sekikaic acid	Amylases Glucosidase	Metabolic Disease
Sekikaic acid is an α-glucosidase (Glucosidase) and α-amylase (Amylases) inhibitor with hypolipidemic, antioxidant and antidiabetic activities. Sekikaic acid significantly reduces LDL, total cholesterol, and total glyceride levels and causes pancreatic beta cell regeneration .

HY-W012946

2-Furoic acid Furan-2-carboxylic acid	ATP Citrate Lyase Acyltransferase Endogenous Metabolite	Metabolic Disease
2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation . 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats .

HY-B1415S

Clofibric acid-d4 Chlorofibrinic acid-d₄	PPAR Drug Metabolite	Others
Clofibric acid-d₄ is the deuterium labeled Clofibric acid. Clofibric acid (Chlorofibrinic acid), the pharmaceutically active metabolite of lipid regulators Clofibrate, Etofibrate and Etofyllinclofibrate, is a PPARα agonist which exhibits hypolipidemic effects. Clofibric acid also is an herbicide[1][2][3].

HY-N6993

25-O-Methylalisol A	Others	Metabolic Disease
25-O-Methylalisol A is a protostane triterpenoids isolated from Alisma orientale. The dried rhizomes of the aquatic plant Alisma orientale known as Rhizoma Alismatis is a common traditional Chinese medicine used for diuretic, anti-inflammatory, and hypolipidemic purposes, as well as the treatment of diabetes .

HY-B1415R

Clofibric acid (Standard) Chlorofibrinic acid (Standard)	PPAR Drug Metabolite	Others
Clofibric acid (Standard) is the analytical standard of Clofibric acid. This product is intended for research and analytical applications. Clofibric acid (Chlorofibrinic acid), the pharmaceutically active metabolite of lipid regulators Clofibrate, Etofibrate and Etofyllinclofibrate, is a PPARα agonist which exhibits hypolipidemic effects. Clofibric acid also is an herbicide .

HY-14739

Choline Fenofibrate ABT-335	PPAR COX	Cardiovascular Disease
Choline Fenofibrate (ABT-335), a choline salt of Fenofibric acid (HY-B0760), releases free Fenofibric acid in the gastrointestinal tract. Fenofibric acid is a PPAR activator with antihyperlipidemic effect .

HY-B0637

Bezafibrate 5 Publications Verification BM15075	PPAR	Cardiovascular Disease Metabolic Disease
Bezafibrate is an agonist of PPAR, with EC₅₀s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.

HY-B0637S

Bezafibrate-d6	PPAR	Cardiovascular Disease Metabolic Disease
Bezafibrate-d₆ is the deuterium labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.

HY-B0637S1

Bezafibrate-d4 BM15075-d₄	Isotope-Labeled Compounds PPAR	Cardiovascular Disease Metabolic Disease
Bezafibrate-d₄ is deuterium labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.

HY-W012946S

2-Furoic acid-d3	Acyltransferase ATP Citrate Lyase Endogenous Metabolite	Metabolic Disease
2-Furoic acid-d₃ is the deuterium labeled 2-Furoic acid[1]. 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[2]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[3].

HY-N1934

Dihydroberberine
Dihydroberberine is a naturally occurring isoquinoline alkaloid with anti-inflammatory, anti-atherosclerotic, hypolipidemic and anti-tumor activities. Dihydroberberine inhibits the human ether-related gene (hERG) channel and significantly reduces the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine also blocks the TLR4/MyD88/NF-κB signaling pathway to reduce pro-inflammatory cytokines and immunoglobulins, and has inhibitory effects on DSS (HY-116282C)-induced experimental colitis. Dihydroberberine also increases the sensitivity of lung cancer to sunitinib (HY-10255A), with synergistic efficacy .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6642

Ankaflavin	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields	PPAR Apoptosis
Ankaflavin, isolated from Monascus-Fermented red rice, is an orally active PPARγ agonist. Ankaflavin exhibits selective cytotoxic effect and induces cell death through apoptosis on cancer cells. Ankaflavin has anti-inflammatory, anti-cancer, antiatherosclerotic, and hypolipidemic effects .

HY-N0652

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside 1 Publications Verification 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside	Structural Classification Stilbenes Classification of Application Fields Polygonaceae Source classification Other Diseases Phenols Polyphenols Fallopia multiflora (Thunb.) Harald. Plants Disease Research Fields	ERK NF-κB
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside isolats from the roots of Polygonaceae species, inhibits the formation of 5-HETE, HHT and thromboxane B2. 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside has hypotensive, anti-ageing, anti-inflammatory, hypolipidemic, cardioprotective, and neuroprotective actions .

HY-N8206

Chrysophanol tetraglucoside	Quinones Structural Classification Monophenols other families Classification of Application Fields Anthraquinones Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Bacterial
Chrysophanol tetraglucoside possesses anti-hypolipidemic and antibacterial activities .

HY-105008

Secoisolariciresinol diglucoside 4 Publications Verification (S,S)-SDG; (S,S)-LGM2605	Cardiovascular Disease Classification of Application Fields Neurological Disease Source classification Lignans Plants Linum usitatissimum Linn. Microorganisms Linaceae Phenols Polyphenols Phenylpropanoids Disease Research Fields	Others
Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects .

HY-N7729

Sekikaic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Amylases Glucosidase
Sekikaic acid is an α-glucosidase (Glucosidase) and α-amylase (Amylases) inhibitor with hypolipidemic, antioxidant and antidiabetic activities. Sekikaic acid significantly reduces LDL, total cholesterol, and total glyceride levels and causes pancreatic beta cell regeneration .

HY-W012946

2-Furoic acid Furan-2-carboxylic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	ATP Citrate Lyase Acyltransferase Endogenous Metabolite
2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation . 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats .

HY-N6993

25-O-Methylalisol A	Triterpenes Structural Classification Alisma plantago-aquatica Linn. Classification of Application Fields Terpenoids Source classification Metabolic Disease Plants Alismataceae Disease Research Fields	Others
25-O-Methylalisol A is a protostane triterpenoids isolated from Alisma orientale. The dried rhizomes of the aquatic plant Alisma orientale known as Rhizoma Alismatis is a common traditional Chinese medicine used for diuretic, anti-inflammatory, and hypolipidemic purposes, as well as the treatment of diabetes .

Cat. No.	Product Name	Chemical Structure

HY-N1214S

Squalene-d6
Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .

HY-B0637S

Bezafibrate-d6
Bezafibrate-d₆ is the deuterium labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.

HY-B1415S

Clofibric acid-d4
Clofibric acid-d₄ is the deuterium labeled Clofibric acid. Clofibric acid (Chlorofibrinic acid), the pharmaceutically active metabolite of lipid regulators Clofibrate, Etofibrate and Etofyllinclofibrate, is a PPARα agonist which exhibits hypolipidemic effects. Clofibric acid also is an herbicide[1][2][3].

HY-B0637S1

Bezafibrate-d4
Bezafibrate-d₄ is deuterium labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, 20 μM for human PPARα, PPARγ and PPARδ, and 90 μM, 55 μM, 110 μM for murine PPARα, PPARγ and PPARδ, respectively; Bezafibrate is used as an hypolipidemic agent.

HY-W012946S

2-Furoic acid-d3
2-Furoic acid-d₃ is the deuterium labeled 2-Furoic acid[1]. 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[2]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[3].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

hypolipidemic

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products