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Results for "

levofloxacin

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

6

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0330
    Levofloxacin
    5 Publications Verification

    (-)-Ofloxacin

    		 Topoisomerase DNA/RNA Synthesis Antibiotic Bacterial Orthopoxvirus Infection Cancer
    Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity .
    <em>Levofloxacin</em>
  • HY-133787
    Levofloxacin N-oxide

    		Drug Metabolite Infection
    Levofloxacin N-oxide is a minor metabolite of Levofloxacin (HY-B0330). Levofloxacin N-oxide does not exhibit significantly genotoxic risks. Levofloxacin is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria .
    <em>Levofloxacin</em> N-oxide
  • HY-B0330A
    Levofloxacin hydrate
    5 Publications Verification

    levofloxacin hemihydrate

    		 Bacterial Antibiotic Topoisomerase DNA/RNA Synthesis Orthopoxvirus Infection Cancer
    Levofloxacin hydrate (Levofloxacin hemihydrate) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrate inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrate can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin hydrate shows anti-orthopoxvirus activity .
    <em>Levofloxacin</em> hydrate
  • HY-B0330BS
    Levofloxacin-d8 hydrochloride

    		Antibiotic
    Levofloxacin-d8 (hydrochloride) is deuterium labeled Levofloxacin (hydrochloride).
    <em>Levofloxacin</em>-d8 hydrochloride
  • HY-B0330B
    Levofloxacin hydrochloride
    5 Publications Verification

    (-)-Ofloxacin hydrochloride
    Levofloxacin ((-)-Ofloxacin) hydrochloride is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrochloride can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin hydrochloride shows anti-orthopoxvirus activity .
    <em>Levofloxacin</em> hydrochloride
  • HY-B0330C
    Levofloxacin sodium

    (-)-Ofloxacin sodium

    		 Antibiotic Orthopoxvirus Bacterial DNA/RNA Synthesis Topoisomerase Infection Inflammation/Immunology
    Levofloxacin ((-)-Ofloxacin) sodium is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin sodium inhibits the DNA gyrase and topoisomerase IV. Levofloxacin sodium can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin sodium shows anti-orthopoxvirus activity .
    <em>Levofloxacin</em> sodium
  • HY-B0330S
    Levofloxacin-d8

    (-)-Ofloxacin-d8

    		 Bacterial Antibiotic Infection
    Levofloxacin-d8 is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
    <em>Levofloxacin</em>-d8
  • HY-B0330S2
    Levofloxacin-13C,d3

    (-)-Ofloxacin-13C,d3

    		 Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Levofloxacin- 13C,d3 is the 13C- and deuterium labeled Levofloxacin.
    <em>Levofloxacin</em>-13C,d3
  • HY-135389
    Desmethyl Levofloxacin

    		Drug Metabolite Antibiotic Infection
    Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication .
    Desmethyl <em>Levofloxacin</em>
  • HY-135389S
    Desmethyl Levofloxacin-d8 hydrochloride

    		Isotope-Labeled Compounds Drug Metabolite Antibiotic Infection
    Desmethyl Levofloxacin-d8 hydrochloride is the deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication .
    Desmethyl <em>Levofloxacin</em>-d8 hydrochloride
  • HY-135389S1
    Desmethyl Levofloxacin-d8

    		Isotope-Labeled Compounds Drug Metabolite Antibiotic Infection
    Desmethyl Levofloxacin-d8 is deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication[1].
    Desmethyl <em>Levofloxacin</em>-d8
  • HY-123319
    Antofloxacin hydrochloride

    		Bacterial Antibiotic Infection
    Antofloxacin hydrochloride is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin hydrochloride shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Antofloxacin hydrochloride is a weak, reversible inhibitor of CYP1A2 for the research of infections caused by a diverse group of bacterial species .
    Antofloxacin hydrochloride
  • HY-123319A
    Antofloxacin

    		Bacterial Antibiotic Infection
    Antofloxacin is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Antofloxacin is a weak, reversible inhibitor of CYP1A2 for the research of infections caused by a diverse group of bacterial species .
    Antofloxacin
  • HY-B0330S1
    (S)-Ofloxacin-d3

    		Bacterial Antibiotic Infection
    (S)-Ofloxacin-d3 is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
    (S)-<em>Ofloxacin</em>-d3
  • HY-157533
    AcrB-IN-5

    		Bacterial Others
    AcrB-IN-5 (compound 8) inhibits AcrB and blocks the efflux pump in a dose-dependent manner .
    AcrB-IN-5
  • HY-162144
    BDM91288

    		Bacterial Infection
    BDM91288 is an orally active AcrB efflux pump inhibitor of pyridinium piperazine. BDM91288 can enhance the in vivo efficacy of levofloxacin (HY-B0330) in the treatment of Klebsiella pneumoniae pulmonary infection in mouse models .
    BDM91288
  • HY-149809
    AcrB-IN-1

    		Bacterial Infection
    AcrB-IN-1 (Compound H6) is a potent AcrB inhibitor. AcrB-IN-1 can be used for the reversal of bacterial multidrug resistance .
    AcrB-IN-1
  • HY-143236
    DHFR-IN-1

    		Bacterial Fungal Infection
    DHFR-IN-1 (compound 12) is a potent and selective DHFR (dihydrofolate reductase)inhibitor, with an IC50 of 40.71 nM. DHFR-IN-1 exhibits promising antibacterial activity against gram-positive and gram-negative bacteria. DHFR-IN-1 exhibits moderate antifungal activities. DHFR-IN-1 exhibits a high synergistic effect with Levofloxacin (HY-B0330), where the FIC (fractional inhibitory concentration index) value is 0.249 .
    DHFR-IN-1

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