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By Targets:	Dopamine Receptor (1) Fluorescent Dye (1) Histamine Receptor (2) Histone Methyltransferase (1)
By Research Areas:	Cancer (1) Neurological Disease (4)

6

Inhibitors & Agonists

1

Fluorescent Dye

14

Recombinant Proteins

8

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Fast Green FCF FD&C Green No. 3; Food green 3; C.I. 42053	Fluorescent Dye	Others
Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF is carcinogenic and acts as a presynaptic locus by inhibiting the release of neurotransmitters in the nervous system .

MS37452	Histone Methyltransferase	Cancer
MS37452 is a potent inhibitor of CBX7 chromodomain binding to H3K27me3, with a K_d of 27.7 μM. MS37452 can derepress transcription of polycomb repressive complex target gene p16/CDKN2A by displacing CBX7 binding to the INK4A/ARF locus in prostate cancer cells .

SKF 38393 hydrobromide (±)-SKF-38393 hydrobromide	Dopamine Receptor	Neurological Disease
SKF 38393 ((±)-SKF-38393) hydrobromide is a selective agonist of the dopamine D1 receptor (D1DR) with an IC₅₀ of 110 nM .

JNJ10191584 maleate VUF6002 maleate	Histamine Receptor	Neurological Disease
JNJ10191584 (VUF6002) maleate (compound 40) is an orally active and selective histamine H₄ receptor antagonist with a K_i value of 26 nM. JNJ10191584 maleate shows 540-fold selectivity to H₄ receptor over the H₃ receptor with a K_i value of 14.1 μM. JNJ10191584 maleate inhibits chemotaxis of eosinophils and mast cells with IC₅₀ values of 530 nM and 138 nM, respectively .

JNJ10191584 VUF6002	Histamine Receptor	Neurological Disease
JNJ10191584 (VUF6002) is an orally active and selective histamine H₄ receptor antagonist with a K_i value of 26 nM. JNJ10191584 shows 540-fold selectivity to H₄ receptor over H₃ receptor with a K_i value of 14.1 μM. JNJ10191584 inhibits chemotaxis of eosinophils and mast cells with IC₅₀ values of 530 nM and 138 nM, respectively .

DSP-4 hydrochloride 1 Publications Verification Neurotoxin DSP 4 hydrochloride	Others	Neurological Disease
DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons .

Species:	Human (9) Mouse (5)
Tag:	His (10) SUMO (2) Tag Free (1) Fc (3)
Source:	HEK293 (6) E. coli Cell-free (1) Sf9 insect cells (1) Sf9 insect cells (1) P. pastoris (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P702582

LY6D Protein, Human (HEK293, Fc)

Ly-6D; lymphocyte antigen 6 complex; locus D
Human HEK293
HY-P702479

TYR/Tyrosinase Protein, Mouse (Cell-Free, His)

Tyrosinase; Albino locus protein; Monophenol monooxygenase
Mouse E. coli Cell-free

	NOTCH4 Protein, Human (sf9, His) Neurogenic locus notch homolog protein 4; hNotch4; INT3	Human	Sf9 insect cells
	NOTCH4 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH4 Protein, Human (sf9, His) is the recombinant human-derived NOTCH4 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of NOTCH4 Protein, Human (sf9, His) is 637 a.a., with molecular weight of ~66.1 kDa.

	NOTCH1 Protein, Mouse (HEK293, His) Neurogenic locus notch homolog protein 1; Notch 1; Motch A; mT14	Mouse	HEK293
	NOTCH1 Protein acts as a receptor for membrane-bound ligands (JAG1, JAG2, and DLL1), determining cell fate. Upon activation, NICD forms a transcriptional activator complex, influencing differentiation, proliferation, and apoptosis. NOTCH1 negatively regulates angiogenesis, endothelial cell behavior, and impacts various developmental processes. It interacts with multiple partners, illustrating its involvement in signaling networks. NOTCH1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived NOTCH1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of NOTCH1 Protein, Mouse (HEK293, His) is 509 a.a., with molecular weight of ~70.0 kDa.

	NOTCH1 Protein, Mouse (sf9, His) Neurogenic locus notch homolog protein 1; Notch 1; Motch A; mT14	Mouse	Sf9 insect cells
	NOTCH1 Protein acts as a receptor for membrane-bound ligands (JAG1, JAG2, and DLL1), determining cell fate. Upon activation, NICD forms a transcriptional activator complex, influencing differentiation, proliferation, and apoptosis. NOTCH1 negatively regulates angiogenesis, endothelial cell behavior, and impacts various developmental processes. It interacts with multiple partners, illustrating its involvement in signaling networks. NOTCH1 Protein, Mouse (sf9, His) is the recombinant mouse-derived NOTCH1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of NOTCH1 Protein, Mouse (sf9, His) is 508 a.a., with molecular weight of ~80 kDa.

	NOTCH1 Protein, Human (HEK293, Fc) Neurogenic locus notch homolog protein 1; Notch 1; Motch A; mT14	Human	HEK293
	NOTCH1 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH1 Protein, Human (HEK293, Fc) is the recombinant human-derived NOTCH1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of NOTCH1 Protein, Human (HEK293, Fc) is 508 a.a., with molecular weight of ~79.7 kDa.

HY-P702622

LY6G6D Protein, Mouse (HEK293, His)

Lymphocyte antigen 6 complex locus protein G6d; Ng25
Mouse HEK293

	Notch3 Protein, Human (HEK293, Fc) CADASIL; CASILneurogenic locus notch homolog protein 3; Notch (Drosophila) homolog 3; notch 3Notch homolog 3 (Drosophila); Notch homolog 3; Notch3; Notch-3	Human	HEK293
	Notch 3 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and plays a crucial regulatory role in cell fate determination. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes within the enhancer of the cleavage site. Notch3 Protein, Human (HEK293, Fc) is the recombinant human-derived Notch3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Notch3 Protein, Human (HEK293, Fc) is 428 a.a., with molecular weight of 75-83 kDa.

	CCL27 Protein, Human rHuCCL27; C-C Motif Chemokine 27; CC Chemokine ILC; Cutaneous T-Cell-Attracting Chemokine; CTACK; Eskine; IL-11 R-Alpha-locus Chemokine; Skinkine; Small-Inducible Cytokine A27; CCL27; ILC; SCYA27	Human	E. coli
	CCL27 Protein, Human is a CC chemokine that binds to the chemokine receptor CCR10, attracts skin-associated memory T lymphocytes, mediates lymphocyte homing to skin sites, and plays a key role in skin inflammation. CCL27 Protein, Human a recombinant human CCL27(F25-G112) protein expressed by E. coli.

	LY6G6D Protein, Human (P.pastoris, His) LY66D_HUMAN; Ly6g6d; Lymphocyte antigen 6 complex locus protein G6d; Megakaryocyte-enhanced gene transcript 1 protein; Protein Ly6-D	Human	P. pastoris
	LY6G6D Protein is a leukocyte antigen-6 (LY6) gene cluster located in the Major Histocompatibility complex (MHC) Class III region of chromosome 6. LY6G6D Protein is involved in the JAK-STAT5 and RAS-MEK-ERK signaling pathways, and is a selective expression of colorectal cancer antigen. Therapeutic T-cell responses can be targeted through T-cell adaptors. LY6G6D Protein, Human (P.pastoris, His) is the recombinant human-derived LY6G6D protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of LY6G6D Protein, Human (P.pastoris, His) is 85 a.a., with homodimer molecular weight of 11 & 22 kDa, respectively.

	CCL27 Protein, Human (N-His) rHuCCL27; C-C Motif Chemokine 27; CC Chemokine ILC; Cutaneous T-Cell-Attracting Chemokine; CTACK; Eskine; IL-11 R-Alpha-locus Chemokine; Skinkine; Small-Inducible Cytokine A27; CCL27; ILC; SCYA27	Human	E. coli
	CCL27 protein selectively attracts skin-associated memory T-lymphocytes, mediating their homing to cutaneous sites through CCR10 binding. Crucial for skin immunity regulation, CCL27 exists as a monomer, dimer, and tetramer, with heparin promoting its oligomerization. Interaction with TNFAIP6, particularly through its Link domain, implies regulatory roles in skin immune responses and inflammation within the skin microenvironment. CCL27 Protein, Human (N-His) is the recombinant human-derived CCL27 protein, expressed by E. coli , with N-His labeled tag. The total length of CCL27 Protein, Human (N-His) is 88 a.a., with molecular weight of ~14 kDa.

	DCT Protein, Mouse (His-SUMO) Dct; Tyrp-2; Tyrp2; L-dopachrome tautomerase; DCT; DT; EC 5.3.3.12; DOPAchrome conversion factor; DOPAchrome isomerase; DOPAchrome oxidoreductase; L-dopachrome Delta-isomerase; SLATY locus protein; Tyrosinase-related protein 2; TRP-2; TRP2	Mouse	E. coli
	DCT (Dopachrome tautomerase) is pivotal in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a critical step in melanin synthesis. DCT's enzymatic activity is integral to the complex processes governing melanin production, emphasizing its role in skin pigmentation and the regulation of melanin-related functions. DCT Protein, Mouse (His-SUMO) is the recombinant mouse-derived DCT protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag. The total length of DCT Protein, Mouse (His-SUMO) is 449 a.a., with molecular weight of ~69.7 kDa.

	HLA-G Protein, Human (HEK293, His) B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA class I histocompatibility antigen alpha chain G; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC G; T-cell A locus; TCA	Human	HEK293
	HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. HLA-G Protein, Human (HEK293, His) is the recombinant human-derived HLA-G protein, expressed by HEK293 , with N-His labeled tag. The total length of HLA-G Protein, Human (HEK293, His) is 314 a.a., with molecular weight of ~39.6 kDa.

	HLA-G Protein, Human (His-SUMO) B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA class I histocompatibility antigen alpha chain G; HLA class I histocompatibility antigen; alpha chain G; HLA class I molecule; HLA G; HLA G antigen; HLA G histocompatibility antigen class I G; HLA G3; HLA-G; HLA-G histocompatibility antigen; class I; HLA60; HLAG; HLAG_HUMAN; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC G; T-cell A locus; TCA	Human	E. coli
	HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. HLA-G Protein, Human (His-SUMO) is the recombinant human-derived HLA-G protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of HLA-G Protein, Human (His-SUMO) is 314 a.a., with molecular weight of ~51.6 kDa.

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