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Results for "

long-acting

" in MCE Product Catalog:

144

Inhibitors & Agonists

13

Peptides

1

Inhibitory Antibodies

7

Natural
Products

29

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas
  • HY-A0285
    Norethisterone enanthate

    Norigest

    Progesterone Receptor Endocrinology
    Norethisterone enanthate is a long-acting parenteral progestogen. Norethisterone enanthate is orally active.
  • HY-17404
    Cilnidipine

    FRC-8653

    Calcium Channel Cardiovascular Disease
    Cilnidipine is a long-acting, second-generation dihydropyridine Ca 2+-channel blocker on L and N-type Ca 2+ channel. Antihypertensive effects.
  • HY-B1904
    Fluphenazine decanoate

    Dopamine Receptor Neurological Disease
    Fluphenazine decanoate is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. Fluphenazine decanoate is also a high and continuous dopamine D2 receptor blocker.
  • HY-B1667
    Isopropamide iodide

    Others Metabolic Disease
    Isopropamide iodide is a long-acting quaternary anticholinergic agent. Isopropamide iodide is used in peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.
  • HY-106541
    Neticonazole

    Fungal Cancer Infection
    Neticonazole is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole has anti-infection and anti-cancer effects.
  • HY-128365
    Neticonazole hydrochloride

    Fungal Cancer Infection
    Neticonazole hydrochloride is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole hydrochloride has anti-infection and anti-cancer effects.
  • HY-108908
    (Rac)-Modipafant

    UK-74505

    Others Infection Inflammation/Immunology
    (Rac)-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist. (Rac)-Modipafant prevents dengue infection.
  • HY-B0743A
    Pipecuronium bromide

    nAChR Neurological Disease
    Pipecuronium bromide is a potent long-acting nondepolarizing steroidal neuromuscular blocking agent (NMBA), and a bisquaternary ammonium compound. Pipecuronium bromide is a powerful competitive nAChR antagonist with a Kd of 3.06 μM.
  • HY-A0019A
    Paliperidone palmitate

    9-Hydroxyrisperidone palmitate

    Dopamine Receptor 5-HT Receptor Neurological Disease
    Paliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester prodrug of Paliperidone. Paliperidone is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class. Paliperidone palmitate shows efficacy against schizophrenia.
  • HY-13568
    Benoxaprofen

    LRCL 3794

    COX Inflammation/Immunology
    Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound. Benoxaprofen is a relatively weak inhibitor of cyclooxygenase in in vitro systems, inhibits lipoxygenase in other systems, and inhibits monocyte migration in some animal models of inflammation.
  • HY-P3291
    Dapiglutide

    ZP7570

    GCGR Metabolic Disease
    Dapiglutide (ZP7570) is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist. Dapiglutide can be used for short bowel syndrome (SBS) research.
  • HY-B0328
    Triamcinolone

    Glucocorticoid Receptor Cancer Inflammation/Immunology Endocrinology
    Triamcinolone is a long-acting synthetic corticosteroid.
  • HY-120423
    AM-6538

    Cannabinoid Receptor Neurological Disease
    AM6538 is a long-acting, high affinity and pseudo-irreversible cannabinoid (CB) antagonist. AM6538 is a structural analog of rimonabant. AM6538 can be effectively used to evaluate the apparent efficacy of cannabinoid full and partial agonists. AM6538 may be useful in future studies that require temporary reductions in cannabinoid receptor availability.
  • HY-A0071
    Tildipirosin

    Bacterial Antibiotic Infection
    Tildipirosin, a long-acting macrolide, has antibiotic activity.
  • HY-A0250
    Tasosartan

    WAY-ANA 756

    Angiotensin Receptor Cardiovascular Disease Endocrinology
    Tasosartan is a long-acting angiotensin II (AngII) receptor antagonist.
  • HY-B2168
    Mequitazine

    LM-209

    Histamine Receptor Inflammation/Immunology Endocrinology
    Mequitazine is a potent, and long-acting histamine H1 antagonist.
  • HY-B1387
    Sulfamethoxypyridazine

    PD-1/PD-L1 Bacterial Antibiotic Infection
    Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic, for treatment of Dermatitis herpetiformis.
  • HY-14751
    Rolapitant

    SCH619734

    Neurokinin Receptor Cancer Neurological Disease
    Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model.
  • HY-B0917
    Bromindione

    Fluidane; Halinone

    Others Cardiovascular Disease
    Bromindione is a potent, long-acting, inandione-derived, oral anticoagulant compound.
  • HY-119447
    Mavacoxib

    COX Inflammation/Immunology
    Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID). Mavacoxib is used to treat pain and inflammation associated with degenerative joint disease in dogs.
  • HY-U00018
    (±)-Tazifylline

    Histamine Receptor Neurological Disease Endocrinology
    (±)-Tazifylline is a potent, selective and long-acting histamine H1 receptor antagonist.
  • HY-U00044
    Anipamil

    Calcium Channel Cardiovascular Disease
    Anipamil is a long-acting calcium channel blocker, used for the treatment of cardiovascular disease.
  • HY-A0130
    Sulfalene

    Sulfametopyrazine; AS-18908

    Parasite Bacterial Antibiotic Infection
    Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial.
  • HY-B0901
    Bromperidol

    R-11333

    5-HT Receptor Neurological Disease
    Bromperidol is a butyrophenone derivative, is a potent and long-acting neuroleptic, used as an antipsychotic in the treatment of schizophrenia.
  • HY-139858
    TGFβR-IN-1

    TGF-β Receptor Cancer
    TGFβR-IN-1 is a long-acting tumor-activated prodrug of a TGFβR inhibitor.
  • HY-105218
    Ifetroban

    Prostaglandin Receptor Cardiovascular Disease Endocrinology
    Ifetroban is a long-acting thromboxane A2 receptor antagonist, with antiplatelet activity.
  • HY-14463
    Onalespib

    AT13387

    HSP Cancer
    Onalespib (AT13387) is a long-acting second-generation Hsp90 inhibitor with a Kd of 0.71 nM.
  • HY-117766
    PC945

    Fungal Cytochrome P450 Infection
    PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 μM and 0.22 μM, respectively.
  • HY-119447S
    Mavacoxib-d4

    COX Inflammation/Immunology
    Mavacoxib-d4 is the deuterium labeled Mavacoxib. Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID). Mavacoxib is used to treat pain and inflammation associated with degenerative joint disease in dogs.
  • HY-U00103
    Triamcinolone hexacetonide

    Others Inflammation/Immunology
    Triamcinolone hexacetonide is a commonly used long-acting steroids in treatment of subacute and chronic inflammatory joint diseases.
  • HY-107947
    Fluphenazine enanthate

    Others Neurological Disease
    Fluphenazine enanthate is the first long-acting injectable (LAI) antipsychotic for the treatment of schizophrenia.
  • HY-17365
    Octreotide acetate

    SMS 201-995 acetate

    Somatostatin Receptor Inflammation/Immunology Cardiovascular Disease Endocrinology Cancer
    Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
  • HY-141862
    Zanamivir-Cholesterol Conjugate

    Influenza Virus Infection
    Zanamivir–cholesterol conjugate is a long-acting neuraminidase inhibitor with potent efficacy against drug-resistant influenza viruses.
  • HY-108719
    Insulin glargine

    Insulin Receptor Metabolic Disease
    Insulin glargine is a long-acting insulin analog. Insulin glargine can be used for the diabetes mellitus.
  • HY-15592
    Cabotegravir

    GSK-1265744; S/GSK1265744

    HIV HIV Integrase Infection
    Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection.
  • HY-U00131
    Sulfabrom

    N 3517; Sulfabromomethazine

    Bacterial Infection
    Sulfabrom (N 3517; Sulfabromomethazine) is a long-acting Sulfonamide that is used for the treatment of coccidiosis and various bacterial infections in the poultry, swine and cattle.
  • HY-P0098
    [D-Ala2]leucine-enkephalin

    Opioid Receptor Cancer
    [D-Ala2]leucine-enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin.
  • HY-16762
    Artefenomel

    OZ439

    Parasite Ferroptosis Infection
    Artefenomel (OZ439) is a synthetic antimalarial agent with the artemisinin pharmacophore. Artefenomel (OZ439) is a long-acting artemisinin-related agent.
  • HY-B0901S
    Bromperidol-d4

    5-HT Receptor Neurological Disease
    Bromperidol-d4 is the deuterium labeled Bromperidol. Bromperidol is a butyrophenone derivative, is a potent and long-acting neuroleptic, used as an antipsychotic in the treatment of schizophrenia.
  • HY-13443
    Exendin-4

    Exenatide

    GCGR Metabolic Disease
    Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM.
  • HY-13443A
    Exendin-4 acetate

    Exenatide acetate

    GCGR Metabolic Disease
    Exendin-4 acetate (Exenatide acetate), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM.
  • HY-B0130
    Perindopril

    S-9490

    Angiotensin-converting Enzyme (ACE) Cancer Cardiovascular Disease
    Perindopril (S-9490) is a long-acting ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.
  • HY-P0165
    Taspoglutide

    ITM077; R1583; BIM51077

    GCGR Metabolic Disease
    Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist developed for treatment of type 2 diabetes, with an EC50 value of 0.06 nM.
  • HY-145786
    Abiraterone decanoate

    Cytochrome P450 Cancer
    Abiraterone decanoate is a potent Abiraterone prodrug. Abiraterone decanoate provide a controlled release of Abiraterone and long-acting CYP17 inhibition with intramuscular (IM) delivery.
  • HY-B1655
    Fluspirilene

    R 6218; Redeptin

    Calcium Channel Neurological Disease
    Fluspirilene is a non-competitive antagonist of L-type calcium channels with an IC50 of 0.03 μM. Fluspirileneis a long-acting injectable depot antipsychotic drug used for schizophrenia.
  • HY-100640
    Roflumilast Impurity E

    Phosphodiesterase (PDE) Inflammation/Immunology
    Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a drug which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM.
  • HY-16183
    Echothiopate iodide

    Echothiophate iodide

    Cholinesterase (ChE) Neurological Disease
    Echothiopate iodide is a potent hBChE (human butyrylcholinesterase) inhibitor. Echothiopate iodide is a long-acting anticholinesterase agent. Echothiopate iodide can be used for glaucoma research.
  • HY-B0213
    Sulfameter

    Sulfametoxydiazine; 5-Methoxysulfadiazine

    Antibiotic Bacterial Infection
    Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis.
  • HY-A0130S
    Sulfalene-13C6

    Sulfametopyrazine-13C6; AS-18908-13C6

    Parasite Bacterial Antibiotic Infection
    Sulfalene-13C6 is the 13C6 labeled Sulfalene. Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial.
  • HY-131579
    Deschloro Cetirizine dihydrochloride

    Others Inflammation/Immunology
    Deschloro Cetirizine Dihydrochloride is a Cetirizine impurity. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist.
  • HY-15981
    Omarigliptin

    MK-3102

    Dipeptidyl Peptidase Metabolic Disease
    Omarigliptin(MK-3102) is a potent, selective and long-acting DPP-4 inhibitor with IC50 of 1.6 nM; highly selective over all proteases tested (IC50 > 67 μM).
  • HY-114118
    Semaglutide

    GCGR Metabolic Disease
    Semaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide has the potential for type 2 diabetes treatment.
  • HY-B1130
    Isoxicam

    COX Inflammation/Immunology
    Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis. Isoxicam is a nonselective inhibitor of COX-1 and COX-2.
  • HY-B0921
    Succinylsulfathiazole

    Succinylsulphathiazole

    Bacterial Antibiotic Infection
    Succinylsulfathiazole is a sulfonamide, it is an ultra long acting drug.
  • HY-14296
    PF-610355

    Adrenergic Receptor Inflammation/Immunology
    PF-610355 is a long-acting inhaled β2-adrenoreceptor agonist, with an EC50 of 0.26 nM. PF-610355 has the potential for the study of asthma and COPD.
  • HY-114118A
    Semaglutide TFA

    GCGR Metabolic Disease
    Semaglutide TFA, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.
  • HY-U00112
    Estradiol 3-sulfamate

    BLE 00084; E2MATE; ES-J 995

    Others Cancer
    Estradiol 3-sulfamate (BLE 00084; E2MATE; ES-J 995) is a potent, long-acting, and orally active steroid sulfatase inhibitor; inhibits estrone sulfatase with an IC50 of 251 nM and a Ki of 133 nM.
  • HY-131256A
    Cetirizine Impurity C dihydrochloride

    Histamine Receptor Endocrinology Inflammation/Immunology
    Cetirizine Impurity C dihydrochloride is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1] [2] .
  • HY-14144
    Aclidinium Bromide

    LAS 34273; LAS-W 330

    mAChR Inflammation/Immunology
    Aclidinium Bromide (LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist. Aclidinium Bromide has the potential for chronic obstructive pulmonary disease (COPD) research.
  • HY-131256
    Cetirizine Impurity C

    Histamine Receptor Endocrinology Inflammation/Immunology
    Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1] [2] .
  • HY-108582
    Y-27152

    Potassium Channel Cardiovascular Disease
    Y-27152, a prodrug of the KATP (Kir6) channel opener Y-26763, is a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state.
  • HY-15445
    CTEP

    RO 4956371; mGluR5 inhibitor

    mGluR Neurological Disease
    CTEP (RO 4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, and shows > 1000-fold selectivity over other mGlu receptors.
  • HY-B0231A
    Enalaprilat

    MK-422 anhydrous

    Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    Enalaprilat (MK-422 anhydrous), the active metabolite of the oral prodrug Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat can be used for the research of hypertension.
  • HY-B2158
    Chlorotrianisene

    Estrogen Receptor/ERR COX Endocrinology Cardiovascular Disease
    Chlorotrianisene is a long-acting non-steroidal estrogen and an orally active estrogen receptor modulator. Chlorotrianisene exhibits antiestrogenic activity. Chlorotrianisene potently inhibits the enzyme COX-1 and inhibits platelet aggregation in whole blood.
  • HY-15553B
    Mibefradil dihydrochloride hydrate

    Ro 40-5967 dihydrochloride hydrate

    Calcium Channel Cardiovascular Disease
    Mibefradil dihydrochloride hydrate (Ro 40-5967 dihydrochloride hydrate) is a effectively long-acting calcium channel antagonist, used as an antihypertensive agent. Mibefradil dihydrochloride hydrate acts via a higher affinity block for low-voltage-activated (T) than for high-voltage-activated (L) calcium channels.
  • HY-B0213S1
    Sulfameter-13C6

    Sulfametoxydiazine-13C6; 5-Methoxysulfadiazine-13C6

    Antibiotic Bacterial Infection
    Sulfameter-13C6 is the 13C6 labeled Sulfameter. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis.
  • HY-B0231
    Enalaprilat dihydrate

    MK-422

    Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    Enalaprilat dihydrate (MK-422), the active metabolite of the oral prodrug Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat dihydrate can be used for the research of hypertension.
  • HY-B0130S
    Perindopril-d4 erbumine

    Angiotensin-converting Enzyme (ACE) Cancer Cardiovascular Disease
    Perindopril-d4 t-butylamine salt is the deuterium labeled Perindopril t-butylamine salt. Perindopril t-butylamine salt is a long-acting ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.
  • HY-17042A
    Cetirizine dihydrochloride

    P071

    Histamine Receptor Inflammation/Immunology Endocrinology
    Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine dihydrochloride marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
  • HY-17404S
    Cilnidipine-d7

    FRC-8653-d7

    Calcium Channel Cardiovascular Disease
    Cilnidipine-d7 is deuterium labeled Cilnidipine. Cilnidipine is a long-acting, second-generation dihydropyridine Ca2+-channel blocker on L and N-type Ca2+ channel. Antihypertensive effects.
  • HY-17042
    Cetirizine

    Histamine Receptor Inflammation/Immunology Endocrinology
    Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
  • HY-14299
    Indacaterol

    Adrenergic Receptor Neurological Disease Endocrinology
    Indacaterol(Onbrez; Arcapta) is an ultra-long-acting β-adrenoceptor agonist.
  • HY-101759
    Isoxsuprine-monoester-1

    Others Cardiovascular Disease
    Isoxsuprine-monoester-1, a monoester of isoxsuprine, is a long acting peripheral vasodilator.
  • HY-14299A
    Indacaterol maleate

    QAB149

    Adrenergic Receptor Endocrinology
    Indacaterol (QAB149) maleate is an ultra-long-acting β-adrenoceptor agonist.
  • HY-14818A
    Laninamivir octanoate

    CS-8958

    Influenza Virus Infection
    Laninamivir octanoate (CS-8958), a prodrug of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses.
  • HY-147257
    Cofrogliptin

    HSK7653

    Dipeptidyl Peptidase Metabolic Disease
    Cofrogliptin (HSK7653) (compound 2), a tetrahydropyran derivative, is a potent oral dipeptidyl aminopeptidase 4 (DPP-4) inhibitor with Long-acting antidiabetic efficacy. Cofrogliptin (compound 2) has a great potential for type 2 diabetes mellitus (T2DM) .
  • HY-100660A
    Cetirizine Impurity B dihydrochloride

    Others Others
    Cetirizine Impurity B dihydrochloride is an impurity of Cetirizine dihydrochloride. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
  • HY-100661
    Cetirizine Impurity D

    Histamine Receptor Endocrinology Inflammation/Immunology
    Cetirizine Impurity D is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
  • HY-A0145
    Phenprocoumon

    Others Others
    Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K.
  • HY-B1424
    Benzthiazide

    Carbonic Anhydrase Cardiovascular Disease Cancer
    Benzthiazide is a long-acting diuretic and a hypertension agent. Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9), with Kis of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells.
  • HY-B0104
    Glimepiride

    Glimperide; HOE-490

    Others Metabolic Disease
    Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.
  • HY-B2158S
    Chlorotrianisene-d9

    Estrogen Receptor/ERR COX Endocrinology Cardiovascular Disease
    Chlorotrianisene-d9 is the deuterium labeled Chlorotrianisene. Chlorotrianisene is a long-acting non-steroidal estrogen and an orally active estrogen receptor modulator. Chlorotrianisene exhibits antiestrogenic activity. Chlorotrianisene potently inhibits the enzyme COX-1 and inhibits platelet aggregation in whole blood.
  • HY-103374
    Phenserine

    (-)-Eseroline phenylcarbamate; (-)-Phenserine

    Cholinesterase (ChE) Amyloid-β Neurological Disease
    Phenserine ((-)-Eseroline phenylcarbamate) is a derivative of Physostigmine and is a potent, noncompetitive, long-acting and selective AChE inhibitor. Phenserine reduces β-amyloid precursor protein (APP) and β-amyloid peptide (Aβ) formation. Phenserine improves cognitive performance and attenuates the progression of Alzheimer's disease.
  • HY-14301
    Olodaterol

    BI1744

    Adrenergic Receptor Inflammation/Immunology Endocrinology
    Olodaterol (BI1744) is a selective, long acting β2-adrenoceptor2-AR) agonist (EC50=0.1 nM and pKi= 9.14 for human β2-adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis.
  • HY-14301A
    Olodaterol hydrochloride

    BI1744 hydrochloride

    Adrenergic Receptor Endocrinology Inflammation/Immunology
    Olodaterol (BI1744) hydrochloride is a selective, long acting β2-adrenoceptor2-AR) agonist (EC50=0.1 nM and pKi= 9.14 for human β2-adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis.
  • HY-17042AS
    Cetirizine D4 dihydrochloride

    Histamine Receptor Inflammation/Immunology
    Cetirizine D4 dihydrochloride is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
  • HY-17042S
    Cetirizine D4

    Histamine Receptor Inflammation/Immunology
    Cetirizine D4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
  • HY-17042S1
    Cetirizine D8

    Histamine Receptor Inflammation/Immunology
    Cetirizine D8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
  • HY-U00302
    CHF5407

    mAChR Inflammation/Immunology
    CHF5407 is a selective, long-acting and competitive muscarinic M3 receptor antagonist. CHF5407 shows subnanomolar affinities for human muscarinic M1 (hM1), M2 (hM2) and M3 (hM3) receptors. CHF5407 shows a prolonged antibronchospastic activity.
  • HY-17042AS1
    Cetirizine D8 dihydrochloride

    Histamine Receptor Inflammation/Immunology
    Cetirizine D8 dihydrochloride is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
  • HY-B1810
    Tulobuterol

    C-78 free base

    Adrenergic Receptor Inflammation/Immunology Endocrinology
    Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength.
  • HY-16952A
    Bepridil hydrochloride hydrate

    (±)-Bepridil hydrochloride hydrate; Org 5730 hydrochloride hydrate

    Calcium Channel Cardiovascular Disease
    Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca + channel antagonist and Na +, K + channel inhibitor, with antianginal and type I antiarrhythmic effects. Bepridil hydrochloride hydrate also acts as a cardiac Na +/Ca2 + exchange (NCX1) inhibitor. Bepridil hydrochloride hydrate can be used for the research of cardiovascular disorders.
  • HY-W224327
    Pheniprazine

    β-Phenylisopropylhydrazine

    Monoamine Oxidase Neurological Disease
    Pheniprazine is a potent and long acting inhibitor of monoamine oxidase. Pheniprazine has the potential for the research of depression.
  • HY-15592S
    Cabotegravir-d3

    GSK-1265744-d3; S/GSK1265744-d3

    HIV HIV Integrase Infection
    Cabotegravir-d3 (GSK-1265744-d3) is the deuterium labeled Cabotegravir. Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection. Cabotegravir is an inhibitor of OAT1 (IC50 0.81 μM) and OAT3 (IC50 0.41 μM).
  • HY-B1424S
    Benzthiazide-d7

    Carbonic Anhydrase Cardiovascular Disease Cancer
    Benzthiazide-d7 is the deuterium labeled Benzthiazide. Benzthiazide is a long-acting diuretic and a hypertension agent. Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9), with Kis of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells.
  • HY-18698
    L-701324

    iGluR Neurological Disease
    L-701324 is an orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor.
  • HY-103374S
    Phenserine-d5

    Cholinesterase (ChE) Amyloid-β Neurological Disease
    Phenserine-d5 is the deuterium labeled Phenserine. Phenserine ((-)-Eseroline phenylcarbamate) is a derivative of Physostigmine and is a potent, noncompetitive, long-acting and selective AChE inhibitor. Phenserine reduces β-amyloid precursor protein (APP) and β-amyloid peptide (Aβ) formation. Phenserine improves cognitive performance and attenuates the progression of Alzheimer's disease.
  • HY-79135
    Pasireotide ditrifluoroacetate

    SOM230 ditrifluoroacetate; Pasireotide TFA salt

    Somatostatin Receptor Endocrinology Cancer
    Pasireotide (SOM230) ditrifluoroacetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide ditrifluoroacetate exhibits antisecretory, antiproliferative, and proapoptotic activity.
  • HY-B0946
    Sulfamonomethoxine

    Bacterial Antibiotic Infection
    Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
  • HY-P9914
    Eculizumab

    Anti-Human C5, Humanized Antibody

    Complement System Cardiovascular Disease
    Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research.
  • HY-106961
    ONO 1301

    ONO-AP 500-02

    Prostaglandin Receptor Cardiovascular Disease
    ONO 1301 (ONO-AP 500-02), a prostaglandin (PG) I2 mimetic, is an orally active, long-acting prostacyclin agonist with thromboxane-synthase inhibitory activity. ONO 1301 promotes production of hepatocyte growth factor (HGF) from various cell types and ameliorates ischemia-induced left ventricle dysfunction in the mouse, rat and pig.
  • HY-108768
    Pasireotide pamoate

    SOM230 pamoate

    Somatostatin Receptor Cancer Endocrinology
    Pasireotide (SOM230) pamoate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity.
  • HY-W011733
    Tulobuterol hydrochloride

    C-78

    Adrenergic Receptor Influenza Virus Antibiotic Infection Endocrinology Inflammation/Immunology
    Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength. Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation.
  • HY-114641A
    BIIL-260 hydrochloride

    Leukotriene Receptor Inflammation/Immunology
    BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1.7 nM.
  • HY-79136
    Pasireotide L-aspartate salt

    SOM230 L-aspartate

    Somatostatin Receptor Cancer Endocrinology
    Pasireotide (SOM230) L-aspartate salt, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide L-aspartate salt exhibits antisecretory, antiproliferative, and proapoptotic activity.
  • HY-17501
    Bambuterol

    (±)-Bambuterol; KWD-2183

    Adrenergic Receptor Endocrinology
    Bambuterol ((±)-Bambuterol; KWD-2183) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.
  • HY-17501A
    Bambuterol hydrochloride

    (±)-Bambuterol hydrochloride; KWD-2183 hydrochloride

    Adrenergic Receptor Endocrinology
    Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.
  • HY-19664
    Pranidipine

    OPC-13340

    Calcium Channel Cardiovascular Disease
    Pranidipine (OPC-13340) is a potent, long acting 1,4-dihydropyridine calcium channel blocker with antihypertensive activity.
  • HY-14818AS
    Laninamivir octanoate-d3

    CS-8958-d3

    Influenza Virus Infection
    Laninamivir octanoate-d3 (CS-8958-d3) is the deuterium labeled Laninamivir octanoate. Laninamivir octanoate (CS-8958), a prodrug of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses.
  • HY-B1810S
    Tulobuterol-D9 hydrochloride

    C-78-D9

    Adrenergic Receptor Inflammation/Immunology Endocrinology
    Tulobuterol-D9 hydrochloride (C-78-D9) is the deuterium labeled Tulobuterol. Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength.
  • HY-14300A
    Vilanterol trifenatate

    GW642444 trifenatate

    Adrenergic Receptor Inflammation/Immunology Endocrinology
    Vilanterol trifenatate (GW642444 trifenatate) is a long-acting β2-adrenoceptor2-AR) agonist with inherent 24-hour activity. The pEC50s for β2-AR, β1-AR and β3-AR are 10.37, 6.98 and 7.36, respectively.
  • HY-B0563C
    Ropivacaine mesylate

    Sodium Channel Potassium Channel Neurological Disease Cardiovascular Disease
    Ropivacaine mesylate is a long-acting amide local anaesthetic agent for a spinal block and effectively blocks neuropathic pain. Ropivacaine blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibressup>[1]. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane.
  • HY-108795
    Albiglutide

    GLP Receptor Metabolic Disease
    Albiglutide, a glucagon-like peptide-1 (GLP-1) mimetic, is a long-acting GLP-1 receptor agonist. Albiglutide significantly reduces glycosylated hemoglobin (A1C). Albiglutide can be used for type 2 diabetes (T2D) research. Albiglutide is generated by the genetic fusion of a DPP-4-resistant GLP-1 dimer to human albumin.
  • HY-14300
    Vilanterol

    GW642444

    Adrenergic Receptor Inflammation/Immunology Endocrinology
    Vilanterol (GW642444) is a long-acting β2-adrenoceptor2-AR) agonist with 24 h activity. The pEC50s for β2-AR,β1-AR and β3-AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively.
  • HY-B0439
    Sulfadoxine

    Sulphadoxine

    Parasite HIV Antibiotic Infection
    Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract and malarial infections. Sulfadoxine inhibits HIV replication in peripheral blood mononuclear cells.
  • HY-B0946S1
    Sulfamonomethoxine-d3

    Bacterial Antibiotic Infection
    Sulfamonomethoxine-d3 is the deuterium labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
  • HY-B1069
    Molsidomine

    SIN-10; Morsydomine

    Drug Metabolite Cardiovascular Disease
    Molsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine, which is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound.
  • HY-14300AS
    Vilanterol-d4 trifenatate

    GW642444-d4 trifenatate

    Adrenergic Receptor Inflammation/Immunology Endocrinology
    Vilanterol-d4 (trifenatate) is deuterium labeled Vilanterol (trifenatate). Vilanterol trifenatate (GW642444 trifenatate) is a long-acting β2-adrenoceptor (β2-AR) agonist with inherent 24-hour activity. The pEC50s for β2-AR, β1-AR and β3-AR are 10.37, 6.98 and 7.36, respectively.
  • HY-16381A
    Pasireotide acetate

    SOM230 acetate

    Somatostatin Receptor Cancer Endocrinology
    Pasireotide (SOM230) acetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide acetate can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide acetate also exhibits antisecretory, antiproliferative, and proapoptotic activity.
  • HY-14532
    Brincidofovir

    CMX001; HDP-CDV

    CMV HSV Orthopoxvirus Infection
    Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo..
  • HY-16381
    Pasireotide

    SOM230

    Somatostatin Receptor Cancer Endocrinology
    Pasireotide (SOM230), a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide also exhibits antisecretory, antiproliferative, and proapoptotic activity.
  • HY-B0946S
    Sulfamonomethoxine-d4

    Bacterial Infection
    Sulfamonomethoxine-d4 is a deuterium labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
  • HY-B0653
    Levobupivacaine

    (S)-(-)-Bupivacaine

    Sodium Channel Ferroptosis Cancer Neurological Disease
    Levobupivacaine ((S)-(-)-Bupivacaine) is a long-acting amide local anaesthetic. Levobupivacaine exerts anaesthetic and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer.
  • HY-B0653A
    Levobupivacaine hydrochloride

    (S)-(-)-Bupivacaine monohydrochloride

    Sodium Channel Ferroptosis Neurological Disease Cancer
    Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a long-acting amide local anaesthetic. Levobupivacaine hydrochloride exerts anaesthetic and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine hydrochloride can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine hydrochloride is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine hydrochloride can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer.
  • HY-17501S
    Bambuterol-d9 hydrochloride

    (±)-Bambuterol-d9 hydrochloride; KWD-2183-d9 hydrochloride

    Adrenergic Receptor Endocrinology
    Bambuterol-D9 ((±)-Bambuterol-D9) hydrochloride is the deuterium labeled Bambuterol. Bambuterol ((±)-Bambuterol) hydrochloride is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.
  • HY-107837
    L-Ascorbic acid 2-phosphate trisodium

    2-Phospho-L-ascorbic acid trisodium

    Phosphatase Reactive Oxygen Species Endogenous Metabolite Metabolic Disease
    L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation.
  • HY-B0439S1
    Sulfadoxine D3

    Sulphadoxine D3

    Parasite HIV Antibiotic Infection
    Sulfadoxine D3 is a deuterium labeled Sulfadoxine. Sulfadoxine is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract and malarial infections. Sulfadoxine inhibits HIV replication in peripheral blood mononuclear cells.
  • HY-B0946S2
    Sulfamonomethoxine-13C6

    Bacterial Antibiotic Infection
    Sulfamonomethoxine-13C6 is the 13C6 labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
  • HY-108751
    Aripiprazole Lauroxil

    Others Neurological Disease
    Aripiprazole lauroxil, an N-acyloxymethyl prodrug of aripiprazole, is a Long-acting injectable (LAI) typical antipsychotic for schizophrenia. Aripiprazole lauroxil is cleaved by body’s enzyme esterase to N-hydroxymethyl aripiprazole (plus lauric acid) and then to aripiprazole (plus formaldehyde), no toxicity.
  • HY-B0439S
    Sulfadoxine-d4

    Sulphadoxine-d4

    Parasite HIV Antibiotic Endogenous Metabolite Infection
    Sulfadoxine-d4 (Sulphadoxine-d4) is the deuterium labeled Sulfadoxine. Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract and malarial infections. Sulfadoxine inhibits HIV replication in peripheral blood mononuclear cells.
  • HY-14277A
    Levocabastine hydrochloride

    R 50547 hydrochloride

    Histamine Receptor Neurotensin Receptor Inflammation/Immunology
    Levocabastine (R 50547) hydrochloride is a long acting, highly potent and selective histamine H1-receptor antagonist with anti-allergic activity. Levocabastine hydrochloride is also a selective, high affinity neurotensin receptor subtype 2 (NTR2) antagonist, with a Ki of 17 nM for mNTR2.
  • HY-103416
    A-77636 hydrochloride

    Dopamine Receptor Neurological Disease
    A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor.
  • HY-B1069S
    Molsidomine-d5

    SIN-10-d5; Morsydomine-d5

    Drug Metabolite Cardiovascular Disease
    Molsidomine-d5 (SIN-10-d5) is the deuterium labeled Molsidomine. Molsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine, which is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound.
  • HY-19304
    Amelubant

    BIIL 284

    Leukotriene Receptor Inflammation/Immunology
    Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 receptor, with Kis of 221 nM and 230 nM in vital cells and membranes. Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity.
  • HY-10791
    Ritanserin

    R 55667

    5-HT Receptor Histamine Receptor Dopamine Receptor Adrenergic Receptor Neurological Disease
    Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors.
  • HY-13625
    Ertapenem sodium

    L-749345; MK-826

    Bacterial Antibiotic Infection Cancer
    Ertapenem sodium (L-749345) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract.
  • HY-A0294A
    Ertapenem disodium

    MK-0826 disodium

    Bacterial Antibiotic Infection
    Ertapenem (MK-0826) disodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract.
  • HY-14277AS
    Levocabastine-d4 hydrochloride

    R 50547-d4 hydrochloride

    Histamine Receptor Neurotensin Receptor Inflammation/Immunology
    Levocabastine-d4 (R 50547-d4) hydrochlorideis the deuterium labeled Levocabastine hydrochloride. Levocabastine (R 50547) hydrochloride is a long acting, highly potent and selective histamine H1-receptor antagonist with anti-allergic activity. Levocabastine hydrochloride is also a selective, high affinity neurotensin receptor subtype 2 (NTR2) antagonist, with a Ki of 17 nM for mNTR2.
  • HY-108795A
    Albiglutide TFA

    GLP Receptor Metabolic Disease
    Albiglutide TFA, a glucagon-like peptide (GLP)-1 mimetic, is a long acting GLP-1 receptor agonist. Albiglutide TFA significantly reduces glycosylated hemoglobin (A1C). Albiglutide TFA can be used for type 2 diabetes (T2D) research. Albiglutide TFA is generated by the genetic fusion of a DPP-4-resistant GLP-1 dimer to human albumin.
  • HY-103701
    L-Ascorbic acid 2-phosphate

    2-Phospho-L-ascorbic acid

    Phosphatase Reactive Oxygen Species Endogenous Metabolite Metabolic Disease
    L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation.
  • HY-103701A
    L-Ascorbic acid 2-phosphate magnesium

    2-Phospho-L-ascorbic acid magnesium

    Phosphatase Reactive Oxygen Species Endogenous Metabolite Metabolic Disease
    L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation.
  • HY-76772
    Cevimeline hydrochloride hemihydrate

    SNI-2011; AF102B hydrochloride hemihydrate

    mAChR Neurological Disease
    Cevimeline hydrochloride hemihydrate (SNI-2011) is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. Cevimeline hydrochloride hemihydrate stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia. Cevimeline hydrochloride hemihydrate can cross the blood-brain barrier (BBB).
  • HY-70020B
    Cevimeline hydrochloride

    AF102B hydrochloride

    mAChR Neurological Disease
    Cevimeline hydrochloride (AF102B hydrochloride) is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. Cevimeline hydrochloride stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia. Cevimeline hydrochloride can cross the blood-brain barrier (BBB).
  • HY-70020
    Cevimeline

    AF102B

    mAChR Neurological Disease
    Cevimeline (AF-102B) is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. Cevimeline stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia. Cevimeline can cross the blood-brain barrier (BBB).