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longevity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) AMPK (1) Amyloid-β (1) Apoptosis (1) Fungal (1) GLUT (1) Isotope-Labeled Compounds (1) NF-κB (1) Parasite (1) Proteasome (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (2)

11

Inhibitors & Agonists

2

Peptides

5

Natural
Products

1

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

MOTS-c(human) acetate	AMPK GLUT	Metabolic Disease
MOTS-c(human) acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity. MOTS-c(human) acetate has implications in the regulation of obesity, diabetes, exercise, and longevity .

Bistrifluron	Others	Cardiovascular Disease
Bistrifluron has insecticidal effects on the larval stage, and also has an effect on adult longevity, reproduction, and hatchability. Bistrifluron is used for the control of a variety of Lepidopterous pests .

(25S)-Δ7-Dafachronic acid Dafachronic acid A; Δ7-Dafachronic acid	Others	Others
(25S)-Δ7-Dafachronic acid is a ligand and activator of DAF-12 receptor. DAF-12 is a nuclear hormone receptor that regulates larval diapause, developmental age, and adult longevity in Caenorhabditis elegans .

24-Methylenecholesterol Ostreasterol	Acyltransferase	Inflammation/Immunology
24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .

HY-N12360

2,3-Dehydrosilybin A

Amyloid-β Neurological Disease

2,3-Dehydrosilybin A is a pro-longevity and anti-aggregation compound .

Galactinol dihydrate	Others	Others
Galactinol dihydrate is a marker for seed longevity. Galactinol dihydrate can scavenge hydroxyl radicals and protect plant cells from oxidative damage caused by MV treatment, salinity, or chilling .

18α-Glycyrrhetinic acid	Proteasome NF-κB Apoptosis	Neurological Disease Inflammation/Immunology Cancer
18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis .

Isolappaol A	Others	Others
Isolappaol A is a natural product that can be isolated from the Arctium lappa. Isolappaol A upregulates the expression of jnk-1, which may promote longevity and stress resistance of C. elegans through the JNK-1-DAF-16 cascade .

HY-133968S1

24-Methylenecholesterol-13C Ostreasterol-¹³C	Isotope-Labeled Compounds	Others
24-Methylenecholesterol- ¹³C (Ostreasterol- ¹³C)is the ¹³C labeled24-Methylenecholesterol(HY-133968) . 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .

α-Terpinene Terpilene	Fungal Parasite	Infection
α-Terpinene (Terpilene) is a monoterpene found in the essential oils of a large variety of foods and aromatic plants such as Mentha piperita. α-Terpinene is active against *Trypanosoma evansi* and has the potential for trypanosomosis treatment. α-Terpinene has antioxidant and antifungal properties .

(2E,4E,6Z)-Methyl deca-2,4,6-trienoate Methyl (2E,4E,6Z)-decatrienoate
(2E,4E,6Z)-Methyl deca-2,4,6-trienoate (Methyl (2E,4E,6Z)-decatrienoate) is the aggregation pheromone of the brown-winged green bug, Plautia stali. (2E,4E,6Z)-Methyl deca-2,4,6-trienoate exposed to daylight in solutions and/or on dispensers used for field trapping can readily isomerize to form complex mixtures of isomers, thus causing a concern about lure stability and longevity .

Cat. No.	Product Name	Category	Target	Chemical Structure

18α-Glycyrrhetinic acid	Triterpenes Classification of Application Fields Neurological Disease Leguminosae Terpenoids Source classification Plants Disease Research Fields Inflammation/Immunology Glycyrrhiza uralensis Fisch.	Proteasome NF-κB Apoptosis
18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis .

α-Terpinene Terpilene	Infection Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields Biological Pesticide Research Agricultural Research	Fungal Parasite
α-Terpinene (Terpilene) is a monoterpene found in the essential oils of a large variety of foods and aromatic plants such as Mentha piperita. α-Terpinene is active against *Trypanosoma evansi* and has the potential for trypanosomosis treatment. α-Terpinene has antioxidant and antifungal properties .

24-Methylenecholesterol Ostreasterol	Structural Classification Classification of Application Fields Anti-aging Source classification Marine natural products Other marine organisms Plants other families Microorganisms Animals Inflammation/Immunology Disease Research Fields Steroids	Acyltransferase
24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .

2,3-Dehydrosilybin A	Structural Classification Flavonols Flavonoids Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Amyloid-β
2,3-Dehydrosilybin A is a pro-longevity and anti-aggregation compound .

Isolappaol A	Structural Classification Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants Compositae Caesalpinia magnifoliolata Metc.	Others
Isolappaol A is a natural product that can be isolated from the Arctium lappa. Isolappaol A upregulates the expression of jnk-1, which may promote longevity and stress resistance of C. elegans through the JNK-1-DAF-16 cascade .

Cat. No.	Product Name	Chemical Structure

HY-133968S1

24-Methylenecholesterol-13C
24-Methylenecholesterol- ¹³C (Ostreasterol- ¹³C)is the ¹³C labeled24-Methylenecholesterol(HY-133968) . 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .

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