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Results for "

oocyte

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aquaporin (1) Autophagy (1) Bacterial (2) Biochemical Assay Reagents (1) Calcium Channel (1) CDK (1) DNA/RNA Synthesis (1) Endogenous Metabolite (1) Estrogen Receptor/ERR (1) Fluorescent Dye (1) GABA Receptor (2) Histamine Receptor (1) HIV (1) iGluR (6) Isotope-Labeled Compounds (2) Microtubule/Tubulin (1) nAChR (10) Potassium Channel (12) Reactive Oxygen Species (1) Sodium Channel (5) URAT1 (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (6) Endocrinology (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (3) Neurological Disease (30)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0872

DIPSO	Biochemical Assay Reagents	Others
DIPSO is a biological zwitterionic buffer with the useful pH range from 7.0 to 8.2. DIPSO can interfere meiotic regulation in mouse oocytes. DIPSO also has surfactant activity at 10 mM .

HY-B0942

Benzethonium chloride	nAChR Bacterial	Neurological Disease
Benzethonium chloride inhibits nicotinic acetylcholine receptors in human recombinant α7 and α4β2 neurons in Xenopus laevis oocytes.

HY-W011711

Benzarone Fragivix	URAT1	Metabolic Disease
Benzarone (Fragivix) is a potent human uric acid transporter 1 (hURAT1) inhibitor, with an IC₅₀ of 2.8 μM in oocyte. Benzarone could lower uric acid serum levels .

HY-P5823

Azemiopsin	nAChR	Neurological Disease
Azemiopsin is a potent nicotinic acetylcholine receptor (nAChR) inhibitor with IC₅₀s of 0.18 μM and 22 μM against T. californica nAChR and human α7 nAChR, respectively. Azemiopsin blocks acetylcholine-induced currents in Xenopus oocytes heterologously expressing human muscle-type nAChR .

HY-103067

A1899 S20951	Potassium Channel	Cardiovascular Disease Neurological Disease
A1899 is a potent and highly selective blocker of the K_2P channel TASK-1. A1899 has IC₅₀ values of 35.1 nM and 7 nM for TASK-1 channels expressed in oocytes and CHO cells, respectively. A1899 is also an I_Kur blocker that can be used for the research of cardiovascular diseases .

HY-134124

Glutathione ethyl ester	Reactive Oxygen Species	Inflammation/Immunology
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-18600A

Azimilide dihydrochloride 2 Publications Verification NE-10064 dihydrochloride	Potassium Channel	Cardiovascular Disease
Azimilide (NE-10064) dihydrochloride is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

HY-18600

Azimilide NE-10064	Potassium Channel	Cardiovascular Disease
Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

HY-B0942S

Benzethonium-d7 chloride	Isotope-Labeled Compounds nAChR	Neurological Disease
Benzethonium-d7 chloride is the deuterium labeled Benzethonium chloride. Benzethonium chloride inhibit human recombinant α7 and α4β2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes.

HY-12151

NS 1738 NSC 213859	nAChR	Neurological Disease
NS 1738 (NSC 213859) is a novel positive allosteric modulator of the α7 nAChR, with respect to positive modulation of α7 nAChR (EC₅₀=3.4 μM in oocyte experiments).

HY-110200

TC AQP1 1 m-Phenylenediacrylic acid; m-Benzenediacrylic acid	Aquaporin	Metabolic Disease Cancer
TC AQP1 1 (m-Phenylenediacrylic acid) is a potent AQP1 inhibitor. TC AQP1 1 inhibits AQP1-mediated water flux in oocytes, with an IC₅₀ of 8 μM .

HY-B0942R

Benzethonium chloride (Standard)	nAChR Bacterial	Neurological Disease
Benzethonium (chloride) (Standard) is the analytical standard of Benzethonium (chloride). This product is intended for research and analytical applications. Benzethonium chloride inhibits nicotinic acetylcholine receptors in human recombinant α7 and α4β2 neurons in Xenopus laevis oocytes.

HY-122504

Linoleoyl glycine	Potassium Channel	Neurological Disease
Linoleoyl glycine is a modified polyunsaturated fatty acid. Linoleoyl glycine has activating effects on human KCNQ1/KCNE1 (hKCNQ1/hKCNE1) channels expressed in Xenopus oocytes .

HY-P5785

Heteropodatoxin-2	Potassium Channel	Neurological Disease
Heteropodatoxin-2, a peptides of 30-amino acid, is a heteropodatoxin. Heteropodatoxin-2 blocks Kv4.2 current expressed in Xenopus laevis oocytes in a voltage-dependent manner, with less block at more positive potentials .

HY-B1167

Ajmaline Cardiorythmine; (+)-Ajmaline	Sodium Channel	Cardiovascular Disease
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC₅₀ of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia .

HY-P1269

α-Conotoxin AuIB	nAChR	Neurological Disease
α-Conotoxin AuIB, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC₅₀ of 0.75 μM .

HY-18600AS

Azimilide-d8 dihydrochloride NE-10064-dd₈ dihydrochloride	Isotope-Labeled Compounds Potassium Channel	Cardiovascular Disease
Azimilide-d₈ (dihydrochloride) is the deuterium labeled Azimilide dihydrochloride. Azimilide Dihydrochloride (NE-10064 Dihydrochloride) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

HY-P5785A

Heteropodatoxin-2 TFA	Potassium Channel	Neurological Disease
Heteropodatoxin-2 (TFA), a peptides of 30-amino acid, is a heteropodatoxin. Heteropodatoxin-2 blocks Kv4.2 current expressed in Xenopus laevis oocytes in a voltage-dependent manner, with less block at more positive potentials .

HY-108235

Lanicemine AZD6765	iGluR	Neurological Disease
Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (K_i of 0.56-2.1 μM for NMDA receptor; IC₅₀s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .

HY-P1269A

α-Conotoxin AuIB TFA 1 Publications Verification	nAChR	Neurological Disease
α-Conotoxin AuIB TFA, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC₅₀ of 0.75 μM .

HY-108235A

Lanicemine dihydrochloride AZD6765 dihydrochloride; ARL 15896AR	iGluR	Neurological Disease
Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker (K_i of 0.56-2.1 μM for NMDA receptor; IC₅₀s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .

HY-P3894

P34cdc2 Kinase Fragment	Microtubule/Tubulin	Others
P34cdc2 Kinase Fragment is associated with the completion of DNA replication in yeast mitosis. P34cdc2 Kinase can phosphorylate mitogen-activated protein 2 (MAP2) to regulate microtubules polymerization in Xenopus oocytes meiosis .

HY-P5788

Hemitoxin	Potassium Channel	Neurological Disease
Hemitoxin, a scorpion-venom peptide, is a K ⁺ channel blocker. Hemitoxin blocks rat Kv1.1, Kv1.2 and Kv1.3 channels expressed in Xenopus oocytes with IC₅₀ values of 13 nM, 16 nM and 2 nM, respectively .

HY-P5828

κM-Conotoxin RIIIJ

κM-RIIIJ
Potassium Channel Cardiovascular Disease

κM-Conotoxin RIIIJ (κM-RIIIJ) is a selective Kv1.2 inhibitor with an IC₅₀ of 33 nM .
HY-P5847

α-Conotoxin GIC

nAChR Neurological Disease

α-Conotoxin GIC is a potent and selective α3β2 nicotinic antagonist with an IC₅₀ of 1.1 nM .

κM-Conotoxin RIIIJ κM-RIIIJ	Potassium Channel	Cardiovascular Disease
κM-Conotoxin RIIIJ (κM-RIIIJ) is a selective Kv1.2 inhibitor with an IC₅₀ of 33 nM .

α-Conotoxin GIC	nAChR	Neurological Disease
α-Conotoxin GIC is a potent and selective α3β2 nicotinic antagonist with an IC₅₀ of 1.1 nM .

HY-116483

MPX-007	iGluR	Neurological Disease
MPX-007 is a GluN2A antagonist (IC₅₀: 27 nM). MPX-007 is a tools to probe GluN2A physiology, and to study neuropsychiatric and developmental disorders .

HY-P5180

Hainantoxin-III	Sodium Channel	Neurological Disease
Jingzhaotoxin-V is a peptide that inhibits potassium currents in Xenopus laevis oocytes with an IC₅₀ value of 604.2 nM. Jingzhaotoxin-V also inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC₅₀ values of 27.6 and 30.2 nM, respectively .

HY-101043

4-PPBP maleate
4-PPBP maleate is a potent σ 1 receptor ligand and agonist. 4-PPBP maleate is a non-competitive, selective NR1a/2B NMDA receptors (expressed in Xenopus oocytes) antagonist. 4-PPBP maleate provides neuroprotection .

HY-N7710

FF-MAS	Others	Metabolic Disease
FF-MAS is a potent meiotic maturation agonist. FF-MAS promotes meiotic maturation and preimplantation development of mouse oocytes maturing in vitro. FF-MAS promotes the completion of meiotic maturation to metaphase II (MII) and improves competence to complete the 2-cell stage to blastocyst transition .

HY-108235B

(Rac)-Lanicemine (Rac)-AZD6765	iGluR	Neurological Disease
(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (K_i of 0.56-2.1 μM for NMDA receptor; IC₅₀s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .

HY-D0152

Tetramethylrhodamine-6-maleimide	Fluorescent Dye	Others
Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time .

HY-P5809

Pe1b

μ-TrTx-Pe1b
Sodium Channel Neurological Disease

Pe1b (μ-TrTx-Pe1b) is a selective Na_v1.7 inhibitor with an IC₅₀ of 167 nM .

Pe1b μ-TrTx-Pe1b	Sodium Channel	Neurological Disease
Pe1b (μ-TrTx-Pe1b) is a selective Na_v1.7 inhibitor with an IC₅₀ of 167 nM .

HY-P5810

Ceratotoxin-2 CcoTx2; β-TRTX-cm1b	Sodium Channel	Neurological Disease
Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC₅₀s of 8 nM and 88 nM against Na_v1.2/β₁ and Na_v1.3/β₁, respectively .

HY-108235C

(R)-Lanicemine (R)-AZD6765	iGluR	Neurological Disease
(R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (K_i of 0.56-2.1 μM for NMDA receptor; IC₅₀s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .

HY-P5871

Jingzhaotoxin-XII JzTx-XII	Potassium Channel	Others
Jingzhaotoxin-XII (JzTx-XII) is a specific Kv4.1 channel inhibitor with an IC₅₀ of 0.363 μM. Jingzhaotoxin-XII interacts with the channels by modifying the gating behavior .

HY-P5770

Jingzhaotoxin-V	Sodium Channel	Neurological Disease
Jingzhaotoxin-V, a 29-residue polypeptide, is derived from the venom of the spider Chilobrachys jingzhao. Jingzhaotoxin-V inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC₅₀ values of 27.6 nM and 30.2 nM, respectively. Jingzhaotoxin-V also inhibits Kv4.2 potassium currents expressed in Xenpus Laevis oocytes (IC₅₀ of 604.2 nM) .

HY-B0463

Clomiphene citrate 4 Publications Verification Clomifene citrate	Estrogen Receptor/ERR	Neurological Disease Endocrinology Cancer
Clomiphene citrate (Clomifene citrate) is an orally active estrogen-receptor modulator. Clomiphene citrate has anti-cancer actixity, induces perturbations during meiotic maturation and cytogenetic abnormalities and ameliorates in managing psychiatric and cognitive impairment .

HY-16916

NS1643 1 Publications Verification	Potassium Channel Autophagy	Cancer
NS1643 is a partial agonist of human ether-a-go-go-related gene (hERG) K ⁺ channels with an EC₅₀ of 10.5 μM. NS1643 inhibits the growth of breast cancer tumors in TNBC mouse models. NS1643 inhibits cell migration and invasion of breast cancer cells .

HY-103066

Br-PBTC	nAChR	Neurological Disease
Br-PBTC is a potent, 2/4 subtype-selective positive allosteric modulator of nAChRs (nicotinic acetylcholine receptors) with α2β2，α2β4，α4β2，α4β4，(α4β2)₂α4 and (α4β2)₂β2 EC₅₀ ranges from 0.1~0.6 μM. Br-PBTC acts from the c-tail of an α subunit .

HY-128036B

ddATP trisodium 2',3'-Dideoxyadenosine 5'-triphosphate trisodium	DNA/RNA Synthesis HIV	Infection
ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection .

HY-13710

Dimethindene	Histamine Receptor Potassium Channel Endogenous Metabolite	Neurological Disease
Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K ⁺ currents .

HY-103522

AA29504	GABA Receptor	Neurological Disease
AA29504 is a ethyl carbamate with γ-aminobutyric acid (GABA_A(HY-L120) receptor activity. AA29504 inhibits the delivery of the neurotransmitter gamma-aminobutyric acid in the central nervous system. AA29504 can be used to research anxiety, insomnia and other neuropsychiatric diseases .

HY-P5860

MmTx1 toxin Micrurotoxin 1	GABA Receptor	Neurological Disease
MmTx1 toxin (Micrurotoxin 1) is an allosteric GABA_A receptor modulator that increases GABA_A receptor susceptibility to agonist .

HY-P5805

ω-Conotoxin CVIE

Calcium Channel Neurological Disease

ω-Conotoxin CVIE is a voltage-gated Ca ²⁺ channel (Ca_v2.2) selective inhibitor .

ω-Conotoxin CVIE	Calcium Channel	Neurological Disease
ω-Conotoxin CVIE is a voltage-gated Ca ²⁺ channel (Ca_v2.2) selective inhibitor .

HY-148939

MPX-004	iGluR	Neurological Disease
MPX-004 is a potent GluN2A antagonist. MPX-004 inhibits GluN2A-containing NMDA receptors expressed in HEK cells with an IC₅₀ of 79 nM. MPX-004 has no inhibitory effect on GluN2B or GluN2D receptor-mediated responses. MPX-004 has the potential for neuropsychiatric and developmental disorders research .

HY-19411

SSR180711 hydrochloride	nAChR	Neurological Disease
SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR (K_i=22 nM; IC₅₀=30 nM) and human α7 n-AChR (K_i=14 nM; IC₅₀=18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus .

HY-W011428

Olomoucine	CDK	Others
Olomoucine is an ATP competitive inhibitor of CDKs. Olomoucine is a purine (HY-34431) derivative and inhibits CDC2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E (both IC₅₀=7 µM), CDK/p35 kinase (IC₅₀=3 µM) and ERK1/p44 MAP kinase (IC₅₀=25 µM) . Olomoucine regulates cell cycle and shows anti-melanin tumor activity .

Cat. No.	Product Name	Target	Research Area

HY-134124

Glutathione ethyl ester	Reactive Oxygen Species	Inflammation/Immunology
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-P5785A

Heteropodatoxin-2 TFA	Potassium Channel	Neurological Disease
Heteropodatoxin-2 (TFA), a peptides of 30-amino acid, is a heteropodatoxin. Heteropodatoxin-2 blocks Kv4.2 current expressed in Xenopus laevis oocytes in a voltage-dependent manner, with less block at more positive potentials .

HY-P5823

Azemiopsin	nAChR	Neurological Disease
Azemiopsin is a potent nicotinic acetylcholine receptor (nAChR) inhibitor with IC₅₀s of 0.18 μM and 22 μM against T. californica nAChR and human α7 nAChR, respectively. Azemiopsin blocks acetylcholine-induced currents in Xenopus oocytes heterologously expressing human muscle-type nAChR .

HY-P5785

Heteropodatoxin-2	Potassium Channel	Neurological Disease
Heteropodatoxin-2, a peptides of 30-amino acid, is a heteropodatoxin. Heteropodatoxin-2 blocks Kv4.2 current expressed in Xenopus laevis oocytes in a voltage-dependent manner, with less block at more positive potentials .

HY-P1269

α-Conotoxin AuIB	nAChR	Neurological Disease
α-Conotoxin AuIB, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC₅₀ of 0.75 μM .

HY-P1269A

α-Conotoxin AuIB TFA 1 Publications Verification	nAChR	Neurological Disease
α-Conotoxin AuIB TFA, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC₅₀ of 0.75 μM .

HY-P3894

P34cdc2 Kinase Fragment	Microtubule/Tubulin	Others
P34cdc2 Kinase Fragment is associated with the completion of DNA replication in yeast mitosis. P34cdc2 Kinase can phosphorylate mitogen-activated protein 2 (MAP2) to regulate microtubules polymerization in Xenopus oocytes meiosis .

HY-P5788

Hemitoxin	Potassium Channel	Neurological Disease
Hemitoxin, a scorpion-venom peptide, is a K ⁺ channel blocker. Hemitoxin blocks rat Kv1.1, Kv1.2 and Kv1.3 channels expressed in Xenopus oocytes with IC₅₀ values of 13 nM, 16 nM and 2 nM, respectively .

HY-P5828

κM-Conotoxin RIIIJ

κM-RIIIJ
Potassium Channel Cardiovascular Disease

κM-Conotoxin RIIIJ (κM-RIIIJ) is a selective Kv1.2 inhibitor with an IC₅₀ of 33 nM .
HY-P5847

α-Conotoxin GIC

nAChR Neurological Disease

α-Conotoxin GIC is a potent and selective α3β2 nicotinic antagonist with an IC₅₀ of 1.1 nM .

HY-P5180

Hainantoxin-III	Sodium Channel	Neurological Disease
Jingzhaotoxin-V is a peptide that inhibits potassium currents in Xenopus laevis oocytes with an IC₅₀ value of 604.2 nM. Jingzhaotoxin-V also inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC₅₀ values of 27.6 and 30.2 nM, respectively .

HY-P5809

Pe1b

μ-TrTx-Pe1b
Sodium Channel Neurological Disease

Pe1b (μ-TrTx-Pe1b) is a selective Na_v1.7 inhibitor with an IC₅₀ of 167 nM .

HY-P5810

Ceratotoxin-2 CcoTx2; β-TRTX-cm1b	Sodium Channel	Neurological Disease
Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC₅₀s of 8 nM and 88 nM against Na_v1.2/β₁ and Na_v1.3/β₁, respectively .

HY-P5871

Jingzhaotoxin-XII JzTx-XII	Potassium Channel	Others
Jingzhaotoxin-XII (JzTx-XII) is a specific Kv4.1 channel inhibitor with an IC₅₀ of 0.363 μM. Jingzhaotoxin-XII interacts with the channels by modifying the gating behavior .

HY-P5770

Jingzhaotoxin-V	Sodium Channel	Neurological Disease
Jingzhaotoxin-V, a 29-residue polypeptide, is derived from the venom of the spider Chilobrachys jingzhao. Jingzhaotoxin-V inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC₅₀ values of 27.6 nM and 30.2 nM, respectively. Jingzhaotoxin-V also inhibits Kv4.2 potassium currents expressed in Xenpus Laevis oocytes (IC₅₀ of 604.2 nM) .

HY-P5860

MmTx1 toxin Micrurotoxin 1	GABA Receptor	Neurological Disease
MmTx1 toxin (Micrurotoxin 1) is an allosteric GABA_A receptor modulator that increases GABA_A receptor susceptibility to agonist .

HY-P5805

ω-Conotoxin CVIE

Calcium Channel Neurological Disease

ω-Conotoxin CVIE is a voltage-gated Ca ²⁺ channel (Ca_v2.2) selective inhibitor .

HY-P1137

10Panx	Peptides	Others
10Panx is a biological active peptide. (This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-1b (IL-1b) in response to P2X7R activation.)

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1167

Ajmaline Cardiorythmine; (+)-Ajmaline	Apocynaceae Cardiovascular Disease Alkaloids Piperidine Alkaloids Structural Classification Rauvolfia serpentina Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids	Sodium Channel
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC₅₀ of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia .

HY-N7710

FF-MAS	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Animals Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Others
FF-MAS is a potent meiotic maturation agonist. FF-MAS promotes meiotic maturation and preimplantation development of mouse oocytes maturing in vitro. FF-MAS promotes the completion of meiotic maturation to metaphase II (MII) and improves competence to complete the 2-cell stage to blastocyst transition .

HY-13710

Dimethindene	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Source classification Pyridine Alkaloids Endogenous metabolite Disease Research Fields	Histamine Receptor Potassium Channel Endogenous Metabolite
Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K ⁺ currents .

Cat. No.	Product Name	Chemical Structure

HY-B0942S

Benzethonium-d7 chloride
Benzethonium-d7 chloride is the deuterium labeled Benzethonium chloride. Benzethonium chloride inhibit human recombinant α7 and α4β2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes.

HY-18600AS

Azimilide-d8 dihydrochloride
Azimilide-d₈ (dihydrochloride) is the deuterium labeled Azimilide dihydrochloride. Azimilide Dihydrochloride (NE-10064 Dihydrochloride) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

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