Search Result
Results for "
orally
" in MedChemExpress (MCE) Product Catalog:
9455
Inhibitors & Agonists
57
Biochemical Assay Reagents
686
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-14401
-
CLTX-305
|
CaSR
|
Others
|
Encaleret (CLTX-305) is an orally active CaSR antagonist .
|
-
-
- HY-147136
-
|
YAP
|
Cancer
|
MYF-03-176 is an orally active and potent anticancer agent. MYF-03-176 shows strong antitumor efficacy in MPM mouse xenograft model via oral administration .
|
-
-
- HY-12422B
-
|
CDK
|
Cancer
|
(2S,3R)-Voruciclib hydrochloride is the enantiomer of Voruciclib hydrochloride. Voruciclib is an orally active CDK inhibitor.
|
-
-
- HY-162877
-
-
-
- HY-127028
-
M-7204
|
Parasite
|
Infection
|
Tripynadine is an anti-malarial compound with oral activity .
|
-
-
- HY-125441
-
-
-
- HY-125694
-
|
Fungal
|
Infection
|
MFB-1041 is an orally active antifungal agent, but exhibits poor oral absorption. MFB-1041 induces the binding of drug to serum albumin .
|
-
-
- HY-W023144
-
Tris(1-chloropropan-2-yl) phosphate
|
Others
|
Others
|
Tris(1-chloro-2-propyl) phosphate is an orally active flame retardant .
|
-
-
- HY-123452
-
-
-
- HY-19596
-
|
Others
|
Inflammation/Immunology
|
Fenprinast is a cromotyn-like bronchodilator used for the research of allergy and exercise-induced asthma. Fenprinast has oral bioactivity .
|
-
-
- HY-120730
-
-
-
- HY-W764737
-
|
Isotope-Labeled Compounds
|
Cancer
|
Methylboronic acid pinacol ester is an orally administered compound that inhibits the activity of peptidases and imidazole derivatives. Methylboronic acid pinacol ester is used as a medicinal preparation for cancer .
|
-
-
- HY-124208
-
-
-
- HY-124208A
-
-
-
- HY-105216
-
-
-
- HY-N7718
-
-
-
- HY-129661
-
|
Opioid Receptor
|
Neurological Disease
|
AH 7959 is an orally active N-substituted cyclohexyl methyl benzamide compound that has analgesic effects, the oral and subcutaneous ED50 of AH 7959 in mice is greater than 100 mg/kg .
|
-
-
- HY-141711
-
|
mAChR
|
Neurological Disease
|
VU6028418 is a potent, highly selective and orally bioavailable M4 mAChR antagonist with an IC50 of 4.1 nM against hM4 .
|
-
-
- HY-119844
-
-
-
- HY-119844A
-
-
-
- HY-131433
-
|
Parasite
|
Infection
|
Teroxalene hydrochloride is an orally active schistosomiasis agent .
|
-
-
- HY-119169
-
|
Microtubule/Tubulin
|
Cancer
|
Tubulozole is an orally active synthetic microtubule inhibitor. Tubulozole can be used for the research of tumor .
|
-
-
- HY-123631
-
-
-
- HY-A0232
-
Medomin
|
Drug Derivative
|
Neurological Disease
|
Heptabarbital (Medomin) is an oral activity Barbituric acid derivative. Heptabarbital has the potential for the research of insomnia .
|
-
-
- HY-B0224
-
-
-
- HY-B0224A
-
-
-
- HY-164138
-
|
17β-HSD
|
Cancer
|
17β-HSD5 inhibitor 3 (Compound 31) is an orally active inhibitor for 17β-HSD5 with an IC50 of 69 nM .
|
-
-
- HY-76511
-
-
-
- HY-107787
-
-
-
- HY-18966
-
-
-
- HY-124419
-
|
mGluR
|
Neurological Disease
|
RO0711401 is a selective and orally active positive allosteric modulator of mGlu1 receptor with an EC50 of 56 nM .
|
-
-
- HY-164648
-
-
-
- HY-120703
-
|
Androgen Receptor
|
Endocrinology
|
RU 58642 is an orally active non-steroidal antiandrogen, which displays a strong and selective affinity for androgen receptor .
|
-
-
- HY-132824
-
-
-
- HY-77591
-
-
-
- HY-106499
-
-
-
- HY-136842
-
-
-
- HY-124225
-
-
-
- HY-15531
-
ABT-199; GDC-0199; RG7601
|
Bcl-2 Family
Autophagy
|
Cancer
|
Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM. Venetoclax induces autophagy .
|
-
-
- HY-13723A
-
SDZ-ASM 981 hydrate
|
Phosphatase
|
Inflammation/Immunology
|
Pimecrolimus hydrate (SDZ-ASM 981 hydrate) is a potent, nonsteroid and orally active calcineurin inhibitor. Pimecrolimus hydrate shows anti-inflammatory activity. Pimecrolimus hydrate has the potential for the research of atopic dermatitis and oral erosive lichen planus .
|
-
-
- HY-105440
-
-
-
- HY-106141
-
UR 9825
|
Fungal
|
Infection
|
Albaconazole (UR 9825) is a broad-spectrum triazole and oral activity antifungal agent .
|
-
-
- HY-W173220
-
-
-
- HY-137442
-
EOS-850
|
Adenosine Receptor
|
Cancer
|
Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity .
|
-
-
- HY-16259
-
Ricainide hydrochloride; LY 135837
|
Sodium Channel
|
Cardiovascular Disease
|
Indecainide hydrochloride is a potent and orally active class I local anesthetic antiarrhythmic agent. Indecainide hydrochloride has Na +-channel-blocking activity .
|
-
-
- HY-A0175
-
-
-
- HY-106571
-
Ro 19-5248; T-2588
|
Bacterial
Antibiotic
|
Infection
|
Cefteram pivoxil (Ro 19-5248), an orally active cephalosporin antibiotic, is used for bacterial infections .
|
-
-
- HY-117891
-
-
-
- HY-147041A
-
(2S)-GB1211
|
Galectin
|
Cancer
|
(2S)-Selvigaltin is the S-enantiomer of Selvigaltin (HY-147041). Selvigaltin is an orally active galectin-3 (Gal-3) inhibitor .
|
-
-
- HY-107647A
-
-
- HY-106067
-
UK 37248 free base
|
Others
|
|
Dazoxiben is a potent and orally active thromboxane synthetase inhibitor. Dazoxiben has the potential for the research of Raynaud's syndrome .
|
-
- HY-155652
-
|
BCRP
|
Cancer
|
ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice .
|
-
- HY-59059
-
|
Monoamine Oxidase
|
Neurological Disease
|
5-(2-Aminopropyl)indole is an orally active psychoactive substance, that shows inhibitory activity against monoamine oxidase (MAO) and long-lasting stimulatory properties .
|
-
- HY-10913A
-
GAP-134 Hydrochloride; ZP 1609 Hydrochloride
|
Gap Junction Protein
|
Cardiovascular Disease
|
Danegaptide Hydrochloride (GAP-134 Hydrochloride) is a potent, selective and orally active gap-junction modifier with an antiarrhythmic effect .
|
-
- HY-15383
-
|
Others
|
Others
|
Glyparamide is an orally active chlorophenyl-containing sulfonylurea. Glyparamide shows hypoglycemic activity and rarely causes hepatic injury .
|
-
- HY-10913
-
-
- HY-154436
-
-
- HY-114929
-
-
- HY-168047
-
|
Virus Protease
|
Infection
|
EBOV-IN-10 is an orally active Ebola virus (EBOV) inhibitor with an EC50 value of 0.19 μM .
|
-
- HY-105332
-
|
CRFR
|
Neurological Disease
|
CRA1000 is an orally active, selective and competitive CRF1 receptor antagonist with anxiolytic- and antidepressant-like properties .
|
-
- HY-100411
-
|
LRRK2
|
Neurological Disease
|
MLi-2 is an orally active and highly selective LRRK2 inhibitor with an IC50 of 0.76 nM. MLi-2 has the potential for Parkinson’s disease .
|
-
- HY-76511S
-
MK-679-d6; L 668019-d6
|
Leukotriene Receptor
|
Inflammation/Immunology
|
Verlukast-d6 is a deuterium labeled Verlukast. Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma[1].
|
-
- HY-139346
-
-
- HY-107533
-
|
GnRH Receptor
|
Endocrinology
|
T-98475 (Compound 26d) is a potent, orally active, non-peptide luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.2 nM .
|
-
- HY-120486
-
-
- HY-16735
-
BCX4161
|
Kallikrein
|
Others
|
Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research .
|
-
- HY-139566
-
3-Nitroxypropanol; 3-NOP
|
Others
|
Others
|
Abrucomstat (3-Nitroxypropanol) is an orally active methyl coenzyme M reductase inhibitor. Abrucomstat decreases ruminal methanogenesis .
|
-
- HY-110274
-
-
- HY-106769
-
-
- HY-162911
-
|
Phosphodiesterase (PDE)
|
Cancer
|
Enpp-1-IN-22 is an orally bioavailable prodrug of the potent ENPP1 inhibitor paraformaldehyde with antitumor activity .
|
-
- HY-106769C
-
GR50360 hydrochloride
|
Adrenergic Receptor
|
Neurological Disease
|
Fluparoxan hydrochloride is an orally active, selective and competitive alpha 2-adrenoceptor antagonist. Fluparoxan hydrochloride is an anti-depressant agent .
|
-
- HY-B1343
-
-
- HY-B1343A
-
-
- HY-145704
-
|
Parasite
|
Infection
|
Antimalarial agent 8 (Compound 7e) is a novel orally active class of antimalarials. Antimalarial agent 8 is potent in vitro against P. falciparum and is orally efficacious (40 mg/kg) in an in vivo mouse model of malaria .
|
-
- HY-B1316
-
-
- HY-155299
-
-
- HY-W011651
-
-
- HY-106538
-
-
- HY-15531R
-
|
Bcl-2 Family
Autophagy
|
Cancer
|
Venetoclax (Standard) is the analytical standard of Venetoclax. This product is intended for research and analytical applications. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM. Venetoclax induces autophagy .
|
-
- HY-124560
-
|
Others
|
Metabolic Disease
|
Lifibrol is a potent and oral activity hypolipidemic agent. Lifibrol decreases the plasma total cholesterol. Lifibrol has the potential for the research of hypercholesterolemia .
|
-
- HY-132894
-
|
Influenza Virus
|
Infection
|
Pixavir marboxilo is an orally active cap-dependent endonuclease inhibitor with high potency. Pixavir marboxilo can be used for the research of influenza .
|
-
- HY-107072A
-
-
- HY-161106
-
|
GPR84
|
Inflammation/Immunology
Cancer
|
OX04528 (compound 68) is a potent, G-protein biased, and orally active GPR84 agonist. OX04528 no cytotoxicity. OX04528 inhibits cAMP production with an EC50 value of 0.00598 nM .
|
-
- HY-118635
-
-
- HY-112736
-
-
- HY-A0165
-
-
- HY-126038
-
-
- HY-106115
-
RGH 2981; RT-3003
|
Others
|
Cardiovascular Disease
|
Vintoperol (RGH 2981; RT-3003) is a potent and orally active antithrombotic agent. Vintoperol interferes with platelet aggregation and shows antithrombotic effects .
|
-
- HY-100704A
-
-
- HY-101566S
-
BAY 1895344-d3
|
ATM/ATR
|
Cancer
|
Elimusertib-d3 (BAY 1895344-d3) is the deuterium labeled Elimusertib (BAY 1895344). Elimusertib is a potent, orally active and selective ATR inhibitor and has anti-tumor activity .
|
-
- HY-170362
-
|
Cyclic GMP-AMP Synthase
|
Inflammation/Immunology
|
cGAS-IN-4 (Compound 36) is an orally active inhibitor for cyclic GMP-AMP synthase (cGAS) with IC50 of 32 nM and 5.8 nM for h-cGAS and m-cGAS. cGAS-IN-4 inhibits the cGAMP in THP-1 cell with an IC50 of 60 nM, which improves the cellular potency. cGAS-IN-4 exhibits anti-inflammatory efficacy in Concanavalin A (HY-P2149)-induced acute liver injury in mouse models .
orally active, THP-1, C57Bl/6 mouse, orally active
|
-
- HY-14560
-
|
Others
|
Neurological Disease
|
Reboxetine is an orally active, potent and selective noradrenaline uptake blocker. Reboxetine can be used for antidepressant research .
|
-
- HY-W017758
-
|
Others
|
Others
|
1,3-Propanediol is produced in nature by the fermentation of glycerol in microorganism, which has orally active .
|
-
- HY-107318
-
-
- HY-101245
-
SUN-1165; Pilzicainide(hydrochloride)
|
Sodium Channel
|
Cardiovascular Disease
|
Pilsicainide hydrochloride (SUN-1165) is an orally active sodium channel blocker and potent class Ic antiarrhythmic agent .
|
-
- HY-W010593
-
|
Drug Metabolite
|
Cancer
|
Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active .
|
-
- HY-N12595
-
|
Others
|
Others
|
22,23-dihydroergosterol is an orally active natural product that can be isolated from Flammulina velutipes .
|
-
- HY-131914A
-
|
Sigma Receptor
|
Neurological Disease
|
EST64454 hydrochloride is a selective and orally active sigma-1 receptor antagonist with a Ki of 22 nM. EST64454 hydrochloride has the potential for the research of the pain .
|
-
- HY-101234
-
|
Histamine Receptor
|
Inflammation/Immunology
|
ICI 162846 is an orally active antagonist of H2 receptor. ICI 162846 inhibits acid production accompanied by an increase in the secretion of histamine in chronic duodenal ulcer (CDU) models. ICI 162846 is effective in preventing CDU .
|
-
- HY-10162
-
AZD2281; KU0059436
|
PARP
Autophagy
Mitophagy
|
Cancer
|
Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator .
|
-
- HY-151141
-
|
Glycosidase
|
Metabolic Disease
|
α-Glucosidase-IN-17 (Compound 12B) is a potent, orally active α-glucosidase inhibitor with an IC50 of 3.79 μM. α-Glucosidase-IN-17 shows antidiabetic activity .
|
-
- HY-170428
-
|
Molecular Glues
Ras
|
Cancer
|
IPS-06061 is an orally active molecule glue, that forms a ternary complex of CRBN-KRASG12D-IPS06061, and degrades KRAS G12D with a DC50 <500 nM .
|
-
- HY-120192
-
|
GABA Receptor
|
Neurological Disease
|
CGP 62349 is a selective and orally active GABAB receptor antagonist that improves cognitive performance in multiple learning paradigms .
|
-
- HY-120634
-
|
HCV
|
Infection
|
BMS-929075 is a potent and orally active HCV NS5B replicase palm site allosteric inhibitor. BMS-929075 shows high oral bioavailability. BMS-929075 shows cytotoxicity .
|
-
- HY-148684
-
|
AMPK
|
Metabolic Disease
|
AMPK activator 10 is an orally active, potent AMPK activator with EC150 of 44.3 nM by cell-ELISA. AMPK activator 10 increases the phosphorylation levels of ACC. AMPK activator 10 exhibits a glucose lowering effect .
|
-
- HY-153113
-
DJT1116PG
|
SGLT
|
Endocrinology
|
Rongliflozin (DJT1116PG) is a selective and orally active inhibitor of sodium-glucose co-transporter-2 (SGLT-2). Rongliflozin can be used for the research of type 2 diabetes mellitus (T2DM) .
|
-
- HY-163300
-
-
- HY-131705
-
|
Btk
|
Inflammation/Immunology
|
BTK inhibitor 17 is a potent and orally active irreversible BTK inhibitor with an IC50 of 2.1 nM. BTK inhibitor 17 can be used for rheumatoid arthritis research .
|
-
- HY-163082
-
|
Galectin
|
Cancer
|
GB1490 is an orally active galectin inhibitor with Kd values of 0.4 μM and 2.7 μM for galectin-1 and galectin-3, respectively .
|
-
- HY-77591R
-
-
- HY-A0165R
-
|
Phosphodiesterase (PDE)
|
Neurological Disease
|
Tofisopam (Standard) is the analytical standard of Tofisopam. This product is intended for research and analytical applications. Tofisopam, a 2,3-benzodiazepine compound, is an orally active anxiolytic agent .
|
-
- HY-10320G
-
BIRB 796 (GMP)
|
p38 MAPK
|
Cancer
|
Doramapimod GMP (BIRB 796 GMP) is an orally active inhibitor for p38 MAPK, with IC50s of 38, 65, 200 and 520 nM, for p38α, p38β, p38γ, p38δ. Doramapimod exhibits cytotoxicity and antitumor activity against multiple myeloma, synergizes with multidrug resistance protein 1 (ABCB1) and aurora kinase inhibitor VX680, promoting their antitumor efficacy against oral epidermoid carcinoma and cervical cancer. Doramapimod also exhibits anti-inflammatory activity .
|
-
- HY-B1682
-
|
Antibiotic
Bacterial
|
Infection
|
Loracarbef, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .
|
-
- HY-B1682A
-
|
Antibiotic
Bacterial
|
Infection
|
Loracarbef hydrate, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .
|
-
- HY-124073
-
|
TRP Channel
|
Metabolic Disease
|
Dihydrocapsiate, as a compound of capsinoid family, is an orally active TRPV1 agonist. Dihydrocapsiate can be used for the research of metabolism disease .
|
-
- HY-106506
-
BW A515U
|
HSV
Apoptosis
Antibiotic
Bacterial
|
Infection
|
Desciclovir is a potent and orally active proagent of the antiherpetic agent Acyclovir (ACV). Desciclovir is converted to acyclovir in vivo by xanthine oxidase .
|
-
- HY-106325
-
-
- HY-114638A
-
BRL 40015 hydrochloride
|
Calcium Channel
|
Cardiovascular Disease
|
Diproteverine hydrochloride is an oral activity calcium channel blocker. Diproteverine hydrochloride embryonic toxicity. Diproteverine hydrochloride also shows antianginal properties .
|
-
- HY-135655A
-
SPR720; pVXc-486
|
Bacterial
|
Infection
|
Fobrepodacin (SPR720) is an orally active and potent phosphate proagent of SPR719 (VXc-486; HY-12930). Fobrepodacin has potent bactericidal activities in vivo .
|
-
- HY-137463
-
-
- HY-163669
-
-
- HY-169953
-
|
Pyk2
|
Metabolic Disease
|
BT-Amide is the orally active inhibitor for Pyk2 kinase with IC50 of 44.69 nM. BT-Amide prevents glucocorticoid-induced bone loss, exhibits bone protective activity in C57BL/6 mouse .
|
-
- HY-123571
-
-
- HY-117507
-
|
5-HT Receptor
|
Neurological Disease
|
U92016A hydrochloride is a potent, metabolically stable, orally acitive 5-HT1A receptor agonist with an exceptionally high degree of intrinsic activity . U92016A hydrochloride binds with high affinity to human 5-HT1A receptors expressed in Chinese hamster ovary cells (Ki=0.2 nM) .
|
-
- HY-12177S
-
-
- HY-142618
-
-
- HY-W013378
-
|
Endogenous Metabolite
|
Neurological Disease
|
Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures .
|
-
- HY-138453
-
LPA1 receptor antagonist 2
|
LPL Receptor
|
Inflammation/Immunology
|
ACT-1016-0707 (Compound 49) is an orally active and selective LPA1 receptor antagonist. ACT-1016-0707 can be used for the research of fibrotic diseases .
|
-
- HY-129914
-
KY-109 free base
|
Bacterial
|
Infection
|
Cefcanel daloxate (KY-109 (free base)) is an orally active cephalosporin prodrug against Gram-positive bacteria and Haemophilus influenzae. Cefcanel daloxate is promising for research of uremia .
|
-
- HY-129708
-
|
Drug Metabolite
|
Neurological Disease
|
LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h .
|
-
- HY-132815
-
MIV-818
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
Fostroxacitabine bralpamide (MIV-818) is an orally active Troxacitabine-based nucleotide proagent. Fostroxacitabine bralpamide has anticancer effects .
|
-
- HY-108685
-
Alendronic acid monosodium salt
|
Others
|
Metabolic Disease
Cancer
|
Alendronate sodium is an orally active nitrogen-containing bisphosphonate. Alendronate sodium potently inhibits bone resorption. Alendronate sodium is used for the research of postmenopausal osteoporosis .
|
-
- HY-14486
-
PRT060128 potassium
|
P2Y Receptor
|
Inflammation/Immunology
|
Elinogrel (PRT060128) potassium is a reversible, competitive and orally active P2Y12 antagonist. Elinogrel potassium inhibits thrombosis .
|
-
- HY-118234
-
|
Bacterial
|
Others
|
(Rac)-PD 138312 is the racemate of PD 138312. PD 138312 is a potent and orally active antibacterial agent against Gram-positive bacteria .
|
-
- HY-159962
-
|
Glutaminase
|
Metabolic Disease
|
TGase2-IN-1 (Compound 22) is an orally active inhibitor for TGase2 with an IC50 of 1.12 μM. TGase2-IN-1 inhibits TGase2 in human retinal microvascular endothelial cells with an IC50 of 0.07 μM. TGase2-IN-1 exhibits 74.6% oral bioavailability. TGase2-IN-1 inhibits retinal vascular leakage in mouse Streptozotocin (HY-13753)-induced diabetic model .
|
-
- HY-120662
-
|
mGluR
|
Neurological Disease
|
GSK1331268 is a selective, orally active agonist for mGluR2 with a pEC50 of 6.9. GSK1331268 exhibits good blood-brain barrier penetration. GSK1331268 regulates glutamate signaling, and can be used in research of neurodegenerative and neuropsychiatric diseases .
|
-
- HY-137979
-
|
UGT
|
Neurological Disease
|
Flunitrazolam is an orally active designer Benzodiazepine. Flunitrazolam is biologically toxic, class in psychoactive substances .
|
-
- HY-17597
-
|
Parasite
|
Infection
|
Febantel is an oral dewormer used to treat gastrointestinal nematodes in sheep, as well as roundworm and tapeworm infections in poultry and livestock, and it also inhibits the embryonic development of mouse hairworms and whipworm eggs .
|
-
- HY-14383
-
-
- HY-133013
-
|
CFTR
|
Inflammation/Immunology
|
GLPG-3221 is a potent, orally active corrector of CFTR (cystic fibrosis transmembrane conductance regulator), with an EC50 of 105 nM. GLPG-3221 can be uesd for the treatment of cystic fibrosis .
|
-
- HY-147993
-
|
Aurora Kinase
|
Cancer
|
Aurora kinase inhibitor-10 (Compound 6c) is an orally active Aurora B inhibitor with an IC50 of 8 nM. Aurora kinase inhibitor-10 shows antitumor activity .
|
-
- HY-109099
-
INCB054828
|
FGFR
|
Cancer
|
Pemigatinib (INCB054828) is an orally active, selective FGFR inhibitor with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma .
|
-
- HY-114638
-
BRL 40015
|
Calcium Channel
|
Cardiovascular Disease
|
Diproteverine (BRL 40015) is an oral activity calcium channel blocker. Diproteverine embryonic toxicity. Diproteverine also shows antianginal properties .
|
-
- HY-50856A
-
S-Ruxolitinib; S-INCB18424
|
JAK
|
Cancer
|
Ruxolitinib (S enantiomer) (S-Ruxolitinib) is the S-enantiomer of Ruxolitinib (HY-50856). Ruxolitinib (S enantiomer) is an orally active, potent JAK inhibitor .
|
-
- HY-B0467S
-
-
- HY-144110
-
|
HCV
|
Infection
|
HCV-IN-37 (Compound 3d) is a potent inhibitor of HCV. HCV-IN-37 is orally available and long-lasting in rat plasma after oral administration to rats by a single dose of 15 mg/kg. The high potency of active derivative HCV-IN-37 is primarily driven by the inhibitory effect on the virus entry stage .
|
-
- HY-106571R
-
|
Bacterial
Antibiotic
|
Infection
|
Cefteram pivoxil (Standard) is the analytical standard of Cefteram pivoxil. This product is intended for research and analytical applications. Cefteram pivoxil (Ro 19-5248), an orally active cephalosporin antibiotic, is used for bacterial infections .
|
-
- HY-144393
-
|
BCRP
|
Cancer
|
P-gp/BCRP-IN-1 (compound 19) is a potential, relatively safe, orally active and efficient efflux transporter (P-gp and BCRP) inhibitor. P-gp/BCRP-IN-1 exerts resistance reversal by inhibiting the efflux function of P-gp and BCRP. P-gp/BCRP-IN-1 can overcome the resistance and improve the oral bioavailability of PTX (Paclitaxel) .
|
-
- HY-B1800
-
-
- HY-106816
-
-
- HY-171174
-
|
CDK
STAT
Wnt
|
Cancer
|
CDK8-IN-16 (Compound 51) is an orally active dual inhibitor for CDK8 and CDK19 wih IC50 of 5.1 nM and 5.6 nM. CDK8-IN-16 inhibits the phospho-STAT1 SER727 with an IC50 of 17.9 nM in SW620 cell, inhibits WNT signaling pathway with an IC50 of 7.2 nM in 7dF3 cell. CDK8-IN-16 exhibits good pharmacokinetic characteristics in rat models with an oral bioavailability of 57% .
|
-
- HY-13236
-
-
- HY-B0487
-
Pregneninolone; 17α-Ethynyltestosterone
|
Estrogen Receptor/ERR
|
Endocrinology
|
Ethisterone (Pregneninolone), a synthetic steroidal estrogen, is an orally active steroidal contraceptive agent. Ethisterone is reported for androgenic activity, used for the research of the gynecological disorders .
|
-
- HY-108504
-
V 102862
|
Sodium Channel
|
Neurological Disease
|
Co 102862 (V 102862) is a potent, broad-spectrum, state-dependent Na + channel blocker. Co 102862 is also an orally active anticonvulsant .
|
-
- HY-148348
-
|
HBV
|
Infection
|
AB-836 is an orally active HBV capsid inhibitor. AB-836 inhibits viral replication by interacting with HBV core protein .
|
-
- HY-14230
-
|
CCR
HIV
|
Infection
|
INCB9471 is a potent, selective and orally active CCR5 antagonist. INCB9471 shows anti-HIV-1 activity .
|
-
- HY-167894
-
-
- HY-19947
-
Glucagon receptor antagonists-4
|
GCGR
|
Metabolic Disease
|
PF-06291874 is a highly potent, non-peptide and orally active glucagon receptor antagonist. PF-06291874 is under the study for type 2 diabetes mellitus (T2DM) .
|
-
- HY-106578
-
LM 208
|
5-HT Receptor
|
Neurological Disease
|
Quinupramine is an orally active antidepressant. Quinupramine can penetrate into the CNS and affect some of the processes of neurotransmission. The antidepressant activity of quinupramine is associated with the central serotonin system, but not with the β-adrenergic system[1][2].
|
-
- HY-17359
-
ICL 670
|
Bacterial
Ferroptosis
|
Cancer
|
Deferasirox (ICL 670) is an orally available iron chelator used for the management of transfusional iron overload .
|
-
- HY-101820
-
|
EGFR
|
Cancer
|
Simotinib is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 19.9 nM. Antineoplastic activities .
|
-
- HY-101820A
-
|
EGFR
|
Cancer
|
Simotinib hydrochloride is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 19.9 nM. Antineoplastic activities .
|
-
- HY-A0252
-
-
- HY-B1363
-
Bendrofluazide
|
Others
|
Cardiovascular Disease
|
Bendroflumethiazide is an orally active diuretic. Bendroflumethiazide is an antihypertensive agent. Bendroflumethiazide has the potential for the research of arterial hypertensive disease .
|
-
- HY-W013331
-
|
Others
|
Inflammation/Immunology
|
Deoxy artemisinin, a orally bioavailable compound separated from Artemisinin annua L., shows anti-inflammatory and antiulcer activities .
|
-
- HY-W392925
-
d-Aminoglutethimide
|
Cytochrome P450
|
Cancer
|
(R)-(+)-Aminoglutethimide is a potent and orally active aromatase inhibitor. (R)-(+)-Aminoglutethimide has the potential for the research of breast cancer .
|
-
- HY-145483
-
KYM-001; PROTAC IRAK4 degrader-7
|
PROTACs
IRAK
Apoptosis
|
Cancer
|
KT-474 (KYM-001) is an orally active PROTAC IRAK4 degrader with antitumor activities . KT-474 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-132196
-
|
Btk
|
Inflammation/Immunology
|
BTK inhibitor 18 is a potent, selective,orally active and covalent Btk inhibitor with a IC50 of 142 nM. BTK inhibitor 18 has anti-inflammatory activities .
|
-
- HY-129695
-
|
Renin
|
Cardiovascular Disease
|
PD 132002 is an orally active, potent renin inhibitor. PD 132002 weakly inhibits pepsin. PD 132002 produces substantial reductions in blood pressure .
|
-
- HY-116746
-
|
Calcium Channel
|
Neurological Disease
|
Clopimozide is an orally active antischizophrenic agent that inhibits [ 3H]nitrendipine binding with IC50 value of 17 nM. Clopimozide is a calcium channel antagonist. Clopimozide can be used for the research of negative and positive schizophrenic symptoms .
|
-
- HY-107730
-
|
Neuropeptide Y Receptor
|
Neurological Disease
|
NPY5RA-972 is an orally active, central nervous system (CNS) penetrating, potent and selective NPY Y5 receptor antagonist that prevents feeding driven by activation of this receptor .
|
-
- HY-129347
-
T-2636E
|
Antibiotic
Bacterial
|
Infection
|
Lankacyclinol A is an orally active antibiotic isolated from Streptomyces rochei. Lankacyclinol A has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Lankacyclinol A exhibits low toxicity in mice .
|
-
- HY-159642
-
|
FGFR
|
Cancer
|
TYRA-300 is an orally active, selective inhibitor for FGFR3 with an IC50 of 11 nM in Ba/F3. TYRA-300 exhibits antitumor efficacy against urothelial cancers and solid tumors .
|
-
- HY-12104
-
|
Cannabinoid Receptor
|
Metabolic Disease
|
PF-514273 is an orally active, selective antagonist for cannabinoid-1 receptor (CB1) with IC50 of 1 nM. PF-514273 reduces the food uptake in mice, and can be used for obesity research .
|
-
- HY-121080
-
|
TRP Channel
|
Neurological Disease
|
AMG8163 is an orally active antagonist for TRPV1. AMG8163 inhibits Capsaicin (HY-10448)-induced flinch in rats models, and exhibits anti-hyperalgesia effects in multiple pain models .
|
-
- HY-12586
-
|
Others
|
Others
|
AZD6564 is an orally active inhibitor for fibrinolysis through disruption of plasma kinase-fibrin interaction. AZD6564 dissolves human plasma clot with an IC50 of 0.44 μM. AZD6564 ameliorates hemorrhage in rats with EC50 of 1.62 μM, and exhibits good pharmacokinetic characteristics in rats .
|
-
- HY-161573A
-
|
YAP
|
Cancer
|
(7S)-BAY-593 is the S-enantiomer of BAY-593 (HY-161573). BAY-593 is an orally active GGTase-I inhibitor. BAY-593 can block YAP1/TAZ signaling in animals and has antitumor activity .
|
-
- HY-114766
-
|
Phosphodiesterase (PDE)
|
Inflammation/Immunology
|
Pumafentrine is an orally active, potent dual PDE3/PDE4 inhibitor. Pumafentrine dose-dependently ameliorates the clinical score and colonic TNFα production in murine Dextran sulphate sodium (DSS; HY-116282C)-induced colitis in a preventive setting .
|
-
- HY-116437
-
|
EGFR
|
Cancer
|
Selatinib is a reversible and orally active dual EGFR and ErbB2 inhibitor with IC50s of 13 nM and 22.5 nM, respectively. Selatinib has anticancer effects .
|
-
- HY-109022
-
MK-8031; AGN-241689
|
CGRP Receptor
|
Neurological Disease
|
Atogepant (MK-8031) is an orally active and selective calcitonin gene–related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine .
|
-
- HY-B1343R
-
|
Cholinesterase (ChE)
|
Neurological Disease
|
Pridinol (mesylate) (Standard) is the analytical standard of Pridinol (mesylate). This product is intended for research and analytical applications. Pridinol mesylate is an orally active and potent central anticholinergic agent, and acts as muscle relaxant .
|
-
- HY-17487
-
Y 0213; Y 9213
|
COX
|
Neurological Disease
Inflammation/Immunology
|
Miroprofen (Y 0213) is an orally active nonsteroidal anti-inflammatory analgesic (NSAID). Miroprofen exhibits anti-inflammatory, analgesic and anti-platelet activities .
|
-
- HY-120474
-
|
Drug Derivative
|
Neurological Disease
|
Ro 23-0364 is an oral active imidazobenzodiazepine agent with mixed benzodiazepine. Ro 23-0364 shows sedative and can be used for study of neurological disease .
|
-
- HY-161731
-
|
Others
|
Cancer
|
DS08701581 is an inhibitor of FER tyrosine kinase with IC50. DS08701581 has anti-tumor activity and oral activity .
|
-
- HY-113671
-
|
Calcium Channel
Acyltransferase
|
Others
|
Belfosdil is an orally active and highly specific calcium channel blocker that also inhibits the activity of acyl coenzyme A cholesterol acyltransferase .
|
-
- HY-153711
-
|
TRP Channel
|
Inflammation/Immunology
|
TRPA1-IN-2 (compound 1) is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM. TRPA1-IN-2 shows anti-inflammation activity .
|
-
- HY-A0107
-
MK-801 maleate
|
Bacterial
Antibiotic
|
Infection
Cancer
|
Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .
|
-
- HY-146075
-
|
Beta-lactamase
Bacterial
|
Infection
|
β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate β-lactamase inhibitor. β-Lactamase-IN-8 can be used for researching antibacteria .
|
-
- HY-151135
-
|
Glycosidase
|
Metabolic Disease
|
α-Glucosidase-IN-15 (Compound 14B) is a potent, orally active α-glucosidase inhibitor with an IC50 of 3.34 μM. α-Glucosidase-IN-15 shows antidiabetic activity .
|
-
- HY-162892
-
|
Others
|
Cancer
|
BRD4-IN-9 is an orally active BRD4 inhibitor with an IC50 value of 9.4 nM. BRD4-IN-9 can suppress tumor growth in a mouse melanoma xenograft model .
|
-
- HY-169423
-
|
DNA/RNA Synthesis
|
Cancer
|
WRN inhibitor 17 (Compound 250) is an orally active Werner Syndrome ATP dependent helicase enzyme (WRN) inhibitor, in particular inhibit WRN helicase domain activity. WRN inhibitor 17 is promising for research of cancers .
|
-
- HY-B1209
-
7-(β-Hydroxyethyl)theophylline
|
Phosphodiesterase (PDE)
|
Cardiovascular Disease
Inflammation/Immunology
|
Etofylline (7-(β-Hydroxyethyl) theophylline) is an oral bronchodilator with anti-inflammatory effects. Etofylline inhibits phosphodiesterase and prevents the degradation of cAMP (cyclic adenosine monophosphate), leading to smooth muscle relaxation, reducing inflammatory responses and improving respiratory function. Etofylline affects the development of zebrafish embryos .
|
-
- HY-10162R
-
|
PARP
Autophagy
Mitophagy
|
Cancer
|
Olaparib (Standard) is the analytical standard of Olaparib. This product is intended for research and analytical applications. Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator .
|
-
- HY-B0996
-
NSC-17764
|
Bacterial
Fungal
|
Infection
Inflammation/Immunology
|
Hexetidine (NSC-17764) is an orally active antibacterial and antifungal agent with broad antibacterial and antifungal activity. Hexetidine combined with IPBC potentiates strong fungal growth inhibition properties. Hexetidine at concentrations greater than 0.1% can cause oral ulceration. Additionally, Hexetidine improves its plaque inhibiting activities combined with zinc and has been confirmed the effectiveness on purulent wound along with ultrasound. Hexetidine is a promising candidate for research in fungus-related diseases and soft tissue purulent-inflammatory
|
-
- HY-W115798
-
Magnesium citrate tribasic nonahydrate, 99%
|
Biochemical Assay Reagents
|
Others
|
Trimagnesium dicitrate nonahydrate, 99% (Magnesium citrate tribasic nonahydrate, 99%) is an orally active magnesium salt of citric acid in the nonahydrate form. Trimagnesium dicitrate nonahydrate, 99% used as a stabilizer and anticaking agent in food supplements in solid and chewable forms .
|
-
- HY-162853
-
|
Bacterial
|
Infection
|
Mtb-IN-8 (compound 5jb) is an orally active inhibitor of Mycobacterium tuberculosis (Mtb) with MIC values of 0.03 μg/mL for H37Rv and 0.125-0.06 μg/mL for MDR-Mtb, respectively .
|
-
- HY-B0714R
-
|
COX
|
Neurological Disease
|
Dexketoprofen (trometamol) (Standard) is the analytical standard of Dexketoprofen (trometamol). This product is intended for research and analytical applications. Dexketoprofen trometamol (Dexketoprofen tromethamine salt) is an orally active non-selective COX inhibitor. Dexketoprofen trometamol has a pain-relieving effect .
|
-
- HY-119245
-
BMS-986166
|
LPL Receptor
|
Inflammation/Immunology
|
Udifitimod (BMS-986166) is a potent, selective and orally active S1P1R modulator. Udifitimod has the potential for the research of autoimmune diseases .
|
-
- HY-42990
-
HSPC
|
Liposome
|
Others
|
Hydrogenated soya phosphatidylcholines is a natural product. Hydrogenated soya phosphatidylcholines can extend drug release in regard to drug loading and solubility for oral drug delivery of watersoluble drugs .
|
-
- HY-W011651R
-
|
Phosphatase
|
Metabolic Disease
|
Carbutamide (Standard) is the analytical standard of Carbutamide. This product is intended for research and analytical applications. Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity .
|
-
- HY-109155
-
CRN00808
|
Somatostatin Receptor
|
Endocrinology
Cancer
|
Paltusotine (CRN00808) is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist. Paltusotine has the potential for maintaining GH and IGF-1 levels after depot somatostatin receptor ligand therapy.Paltusotine can be used in research on acromegaly and neuroendocrine tumors .
|
-
- HY-109155A
-
CRN00808 hydrochloride
|
Somatostatin Receptor
|
Neurological Disease
Endocrinology
|
Paltusotine (CRN00808) hydrochloride is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist. Paltusotine hydrochloride has the potential for maintaining GH and IGF-1 levels after depot somatostatin receptor ligand therapy.Paltusotine hydrochloride can be used in research on acromegaly and neuroendocrine tumors .
|
-
- HY-168522
-
|
Integrin
|
Inflammation/Immunology
|
αvβ6-IN-2 (compound 20) is a potent and orally active αvβ6 integrin inhibitor with a pIC50 value of 7.8. αvβ6-IN-2 has the potential for the research of idiopathic pulmonary fibrosis .
|
-
- HY-18345
-
-
- HY-B1656
-
-
- HY-B1481B
-
Isoetarine hydrochloride
|
Adrenergic Receptor
|
Infection
|
Isoetharine hydrochloride is selective, short-acting and orally active β-agonist which is widely used as a bronchodilator in the research of inhalation research .
|
-
- HY-122075
-
|
Others
|
Metabolic Disease
|
FR 78844 is a potent and orally active bone resorption inhibitor. FR 78844 has the potential for the research of diabetes associated osteopenia .
|
-
- HY-119270
-
|
Biochemical Assay Reagents
|
Cancer
|
PD 130908 is an orally active hypoxic cell radiosensitizer with potent radiosensitizing activity. PD 130908 can be utilized in cancer research .
|
-
- HY-W099437
-
|
Biochemical Assay Reagents
|
Others
|
Diethylene glycol monobutyl ether acetate is an orally available high molecular weight glycol ether solvent that can be used as a coalescing agent for polyvinyl acetate (latex) coatings, the acute oral LD in mice and rats is about 7 g/kg .
|
-
- HY-103459
-
PD156707
|
Endothelin Receptor
|
Cardiovascular Disease
|
CI-1020 (PD156707) is an orally active and selective antagonist targeting endothelin (ETA) with an IC50 value of 0.3 nM. CI-1020 blocks intimal hyperplasia in human saphenous veins completely in organ culture. CI 1020 inhibits hypoxic pulmonary hypertension and blocks ET-1-induced pressor responses following oral administration .
|
-
- HY-155787
-
|
CDK
|
Cancer
|
SHR5428 is a potent, orally active, selective and noncovalent inhibitor of CDK7 with highly potent CDK7 enzymatic activity (IC50=2.3 nM). SHR5428 inhibits triple negative breast cancer cellular activity on MDA-MB-468 cell (IC50=6.6 nM) .
|
-
- HY-118911
-
|
ATM/ATR
|
Cancer
|
ATM Inhibitor-10 (compound 74), a 3-quinoline carboxamide, is a highly selective and orally active ATM inhibitor (IC50: 0.6 nM). ATM Inhibitor-10 has anti-tumor activity in SW620 xenograft models. ATM Inhibitor-10 is synergistic with Top I inhibitors .
|
-
- HY-160532
-
|
Casein Kinase
|
Cancer
|
CK1α degrader-1 (Compound 82) is an orally active CK1α degrader with a DC50 of 0.105 μM. CK1α degrader-1 can be used for the research of cancer .
|
-
- HY-W105835
-
Trimagnesium dicitrate
|
Toll-like Receptor (TLR)
|
Neurological Disease
|
Magnesium citrate is a magnesium salt form that provides efficient penetration into brain and muscle tissue. Magnesium citrate increases pain threshold and reduces TLR4 concentration in the brain. Orally active .
|
-
- HY-146223
-
|
Ras
|
Cancer
|
AZD4625 (Compound 21) is a highly potent, selective, covalent and allosteric inhibitor of the mutant GTPase KRAS G12C. AZD4625 has high oral bioavailability .
|
-
- HY-147411
-
MK-8507
|
Reverse Transcriptase
HIV
|
Infection
|
Ulonivirine (MK-8507) is an orally active non-nucleoside reverse transcriptase inhibitor with high antiviral activity. Ulonivirine can be used for the research of HIV-1 infection .
|
-
- HY-162553
-
|
Ligands for E3 Ligase
|
Cancer
|
GNE7599 is a high-affinity and orally active von Hippel-Lindau (VHL) ligand with a Kd of 540 pM. GNE7599 can be connected to the ligand for protein by a linker to form PROTACs .
|
-
- HY-163832
-
|
Others
|
Metabolic Disease
|
FPPS-IN-2 (compound 4a) is a potent and orally active HFPPS inhibitor with an IC50 value of 1.108 µM. FPPS-IN-2 has the potential for the research of osteoporosis .
|
-
- HY-B1429
-
-
- HY-139588
-
-
- HY-N10379
-
-
- HY-151568
-
|
Parasite
|
Infection
|
UCB7362 is an orally active and potent antimalarial plasmepsin X (PMX) inhibitor, with an IC50 of 7 nM. UCB7362 inhibits parasite growth .
|
-
- HY-119605
-
|
GABA Receptor
|
Neurological Disease
|
DAA-1097 is an orally active and selective agonist for the peripheral benzodiazepine receptor (PBR). DAA-1097 has anxiolytic effects .
|
-
- HY-10267
-
PD-0348292
|
Factor Xa
|
Cardiovascular Disease
|
Eribaxaban (PD-0348292) is an orally active and selective FXa inhibitor with a Ki value of 0.32 nM. Eribaxaban reduces thrombus formation .
|
-
- HY-N7557
-
|
Others
|
Cancer
|
(E)-2'-Hydroxy-3,4-dimethoxychalcone (compound 7) is a Chalcone derivative with orally active. (E)-2'-Hydroxy-3,4-dimethoxychalcone has anti-tumour activities .
|
-
- HY-122661
-
MPH
|
PARP
Apoptosis
|
Cancer
|
Mefuparib hydrochloride (MPH) is an orally active, substrate-competitive and selective PARP1/2 inhibitor with IC50s of 3.2 nM and 1.9 nM, respectively. Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo .
|
-
- HY-143200
-
-
- HY-103179
-
WAG-994; N6-Cyclohexy-2'-0-methyladenosine
|
Adenosine Receptor
|
Cardiovascular Disease
|
SDZ-WAG994 (WAG-994) is a stable, long-acting, selective and orally active A1-adenosine receptor agonist with a KD of 23 nM. SDZ-WAG994 can be used for the research of atrial fibrillation .
|
-
- HY-167675
-
|
5-HT Receptor
|
Others
|
R-137696 is an orally active serotonin-1A (5-HT1A) receptor agonist which relaxes the proximal stomach. R-137696 can be utilized in research related to functional dyspepsia .
|
-
- HY-N12353
-
|
Phosphatase
|
Metabolic Disease
|
Stevisalioside A (Compound 2) can be isolated from Stevia serrata roots. Stevisalioside A is an orally active antidiabetic agent. Stevisaliosides A inhibits PTP1B (IC50: 526.8 μM). Stevisalioside A reduces blood glucose levels and the postprandial peak in oral glucose and insulin tolerance tests in Streptozotocin (HY-13753) induced hyperglycemic mice .
|
-
- HY-139585
-
LC350189
|
Xanthine Oxidase
|
Metabolic Disease
|
Tigulixostat (LC350189) is an orally active, non-purine selective xanthine oxidase inhibitor. Tigulixostat lowers the production of uric acid. Tigulixostat can be used for gout and hyperuricemia study .
|
-
- HY-142687
-
|
SGK
|
Inflammation/Immunology
|
SGK1-IN-4 (compound 17a) is a highly selective, orally active SGK1 inhibitor. SGK1-IN-4 can be used for osteoarthritis research .
|
-
- HY-121776
-
|
Drug Derivative
|
Cardiovascular Disease
|
Nicomol is an orally active hypolipidemic agent that can increase the high density lipoprotein cholesterol (HDL-C) level. Nicomol inhibits the rapid rise of plasma free fatty acids .
|
-
- HY-W010593R
-
|
Drug Metabolite
|
Cancer
|
Ethylenethiourea (Standard) is the analytical standard of Ethylenethiourea. This product is intended for research and analytical applications. Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active .
|
-
- HY-116726
-
|
Glutathione S-transferase
|
Cancer
|
Crambene is an orally active cyanide compound isolated from cruciferous vegetables. Crambene has a cancer-preventive effect and induces significant upregulation of quinone reductase and glutathione S-transferase in vitro and in vivo .
|
-
- HY-117858
-