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Results for "

phosphatidylinositol

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PI4K (4) PIKfyve (1) ADC Antibody (1) Apoptosis (1) Arp2/3 Complex (2) Atg8/LC3 (1) Autophagy (1) Biochemical Assay Reagents (1) CaSR (1) Endogenous Metabolite (1) Endothelin Receptor (1) Fluorescent Dye (1) HCV (1) IGF-1R (1) Isotope-Labeled Compounds (4) P-glycoprotein (1) p62 (1) Phospholipase (1) PI3K (7) PI5P4K (3) PKC (1) Reverse Transcriptase (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (3) Endocrinology (2) Infection (4) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: PIKfyve PI4K

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-139533

Phosphatidylinositols, soya, sodium salts	Others	Others
Phosphatidylinositols, soya, sodium salts is a mixture of phosphatidylinositols. Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids between the different compartments of eukaryotic cells. They act by recruiting and/or activating effector proteins and thus are involved in regulating various cellular functions, such as vesicular budding, membrane fusion and cytoskeleton dynamics .

HY-P2856

Phosphatidylinositol phosphodiesterase	Endogenous Metabolite	Metabolic Disease
Phosphatidylinositol phosphodiesterase hydrolyzes phosphatidylinositol to diacylglycerols and a mixture of myoinositol 1- and 1, 2-cyclic phosphates .

HY-114457

Phosphatidylinositol 4,5-bisphosphate L-alpha-phosphatidylinositol-4,5-bisphosphate	PI3K	Others
Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger .

HY-W854295

Phosphatidylinositol-1,2-dioctanoyl sodium PtdIns-(1,2-dioctanoyl) (sodium)	P-glycoprotein	Cancer
Phosphatidylinositol-1,2-dioctanoyl sodium significantly inhibits transmembrane P-gp transport in a reproducible, cell line-independent, and substrate-independent manner. Phosphatidylinositol-1,2-dioctanoyl sodium plays an important role in signal transduction and cell movement .

HY-146949S

D-Myo-phosphatidylinositol diC16-d5

Isotope-Labeled Compounds Others

D-Myo-phosphatidylinositol diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol diC16.

*D-Myo-phosphatidylinositol* diC16-d5**	Isotope-Labeled Compounds	Others
D-Myo-phosphatidylinositol diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol diC16.

HY-146947S

*D-Myo-phosphatidylinositol* 4-phosphate diC16-d5**	Isotope-Labeled Compounds	Others
D-Myo-phosphatidylinositol 4-phosphate diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol 4-phosphate diC16.

HY-146948S

*D-Myo-phosphatidylinositol* 4,5-bisphosphate diC16-d5**	Isotope-Labeled Compounds	Others
D-Myo-phosphatidylinositol 4,5-bisphosphate diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol 4,5-bisphosphate diC16.

HY-146946S

*D-Myo-phosphatidylinositol* 3,4,5-trisphosphate diC16-d5**	Isotope-Labeled Compounds	Others
D-Myo-phosphatidylinositol 3,4,5-trisphosphate diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol 3,4,5-trisphosphate diC16.

HY-127008

N-Butylfluorescein	Fluorescent Dye	Others
N-Butylfluorescein is an alkyl-substituted fluorescein, can be used for synthesis of fluorogenic substrates for assaying phosphatidylinositol-specific phospholipase C .

HY-W127317

Inositol 1,3,4,5-tetraphosphate

Others Others

Inositol 1,3,4,5-tetraphosphate is the head group of PIP3 (phosphatidylinositol 3,4,5-trisphosphate) .

Inositol 1,3,4,5-tetraphosphate	Others	Others
Inositol 1,3,4,5-tetraphosphate is the head group of PIP3 (phosphatidylinositol 3,4,5-trisphosphate) .

HY-109198

Zandelisib ME-401; PWT-143	PI3K	Cancer
Zandelisib (ME-401) is a phosphatidylinositol 3-kinase (PI3K) inhibitor extracted from patent WO2019183226 A1, Compound Example 1. Zandelisib selectively inhibits p110δ with an IC₅₀ of 3.5 nM. Zandelisib functions as an antineoplastic .

HY-132276

PtdIns-(3,4,5)-P3-biotin sodium	Others	Others
PtdIns-(3,4,5)-P3-biotin sodium is a Biotin-labeled PtdIns-(3,4,5)-P3 (PI(3,4,5)P3). PI(3,4,5)P3 is a substrate of nuclear phosphatidylinositol 5-phosphatase (PIP5Pase). PI(3,4,5)P3 binds to the N-terminus of RAP1 (repressor activator protein 1) and controls its DNA binding activity .

HY-135283

ABT-546 A-216546	Endothelin Receptor	Cardiovascular Disease Endocrinology
ABT-546 (A-216546) is a potent, highly selective and active endothelin ET_A receptor antagonist with a K_i of 0.46 nM for [ ¹²⁵I]endothelin-1 binding to cloned human endothelin ET_A. ABT-546 is >25,000-fold more selective for the ET_A receptor than for the ET_B receptor. ABT-546 blocks endothelin-1-induced arachidonic acid release and phosphatidylinositol hydrolysis with IC₅₀ of 0.59 nM and 3 nM, respectively .

HY-153526

PI5P4Ks-IN-2	PI5P4K	Others
PI5P4Ks-IN-2 is a inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ). PI5P4Ks-IN-2 targets to PI5P4K isoforms with pIC₅₀ values of <4.3 (PI5P4Kα), <4.6 (PI5P4Kβ), 6.2 (PI5P4Kγ), 0.32 (PI5P4Kγ+), respectively .

HY-139041

Palmitoylcholine chloride	Others	Others
Palmitoylcholine chloride reduces membrane stress and reduces enzyme activity by Ca(2+)-dependent phosphatidylinositol phosphodiesterase (EC 3.1.4.10) hydrolysis of phosphatidylinositol monolayers .

HY-125118

GSK-A1	PI4K HCV	Infection
GSK-A1 is a selective *type III phosphatidylinositol* 4-kinase PI4KA (PI4KIIIα) inhibitor with a pIC₅₀ of 8.5-9.8. GSK-A1 inhibits PtdIns(4,5)P2 resynthesis with an IC₅₀ of about 3 nM. GSK-A1 potently decreases the levels of PtdIns(4)P with a negligible effect on PtdIns(4,5)P2. GSK-A1 has the potential for anti-hepatitis C virus (HCV**) research .

HY-124348

DM-PIT-1 3,5-Dimethyl PIT-1	PI3K	Cancer
DM-PIT-1 is a PIP3/PH (phosphatidylinositol-3,4,5-triphosphate/Pleckstrin) interaction inhibitor . DM-PIT-1 has the potential for the research of ovarian cancer .

HY-15784

NPPM 6748-481

Others Others

NPPM 6748-481 is a selective inhibitor of the yeast phosphatidylinositol transfer protein (PITP) Sec14 .

NPPM 6748-481	Others	Others
NPPM 6748-481 is a selective inhibitor of the yeast phosphatidylinositol transfer protein (PITP) Sec14 .

HY-126083

17β-Hydroxywortmannin Wortmannin-17β-ol	PI3K	Others Cancer
17β-Hydroxywortmannin (Wortmannin-17β-ol) is an orally active inhibitor for phosphatidylinositol-3-kinase (PI-3-kinase) with an IC₅₀ of 0.5 nM, suppresses the osteoclast resorption with an IC₅₀ of 10 nM . 17β-Hydroxywortmannin exhibits antitumor activity .

HY-U00426

BF738735

2 Publications Verification

PI4K Reverse Transcriptase Infection

BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC₅₀ of 5.7 nM.

BF738735 2 Publications Verification	PI4K Reverse Transcriptase	Infection
BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC₅₀ of 5.7 nM.

HY-151473

PIKfyve-IN-1	PIKfyve	Infection Cancer
PIKfyve-IN-1 is a highly potent and cell-active chemical probe that inhibits phosphatidylinositol-3phosphate 5-kinase (PIKfyve) with IC₅₀ value of 6.9 nM. PIKfyve-IN-1 can be used for the research of PIKfyve in virology . PIKfyve-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-108313

T-00127_HEV1

2 Publications Verification

PI4K Infection

T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC₅₀ of 60 nM.

T-00127_HEV1 2 Publications Verification	PI4K	Infection
T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC₅₀ of 60 nM.

HY-130405

PtdIns-(1,2-dipalmitoyl) (ammonium)	Others	Metabolic Disease
PtdIns-(1,2-dipalmitoyl) ammonium (DPPI) is a derivative of phosphatidylinositol (PtdIns) that contains C16:0 fatty acyl chains .

HY-101423

NIH-12848

PI5P4K Cardiovascular Disease

NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor with an IC₅₀ of 1 μM.

NIH-12848	PI5P4K	Cardiovascular Disease
NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor with an IC₅₀ of 1 μM.

HY-115769

1,2-Didecanoylglycerol	PKC	Endocrinology
1,2-Didecanoylglycerol, a synthetic diacylglycerol, is metabolized by platelets to 1,2-didecanoylphosphatidic acid (PA₁₀) and activates protein kinase C (PKC) .

HY-109029

Dezapelisib INCB040093	PI3K	Cancer
Dezapelisib (NCB040093) is a potent inhibitor of phosphatidylinositol 3-kinase δ (PI3Kδ). Dezapelisib is a promising research strategy for select R/R B-cell lymphomas .

HY-135680

I-OMe-Tyrphostin AG 538 I-OMe-AG 538	IGF-1R	Metabolic Disease Cancer
I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells. I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC₅₀ of 1 µM .

HY-152155

ARUK2001607	PI5P4K	Inflammation/Immunology Cancer
ARUK2001607 is a selective phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor with a K_d of 7.1 nM. ARUK2001607 shows high selectivity over other >150 kinases .

HY-122819

Calindol hydrochloride	CaSR	Cardiovascular Disease
Calindol hydrochloride is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC₅₀ of 132 nM .

HY-130592

Compound 48/80 trihydrochloride C48/80 trihydrochloride	Phospholipase	Neurological Disease
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets .

HY-103489

PI-273 4 Publications Verification	PI4K Apoptosis	Cancer
PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC₅₀ of 0.47 μM. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis .

HY-103224

PIT-1	PI3K	Cancer
PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo .

HY-147419

Vulolisib	PI3K	Cancer
Vulolisib is a potent and orally active phosphatidylinositol 3-kinase (PI3K) inhibitor, with IC₅₀ values of 0.2 nM, 168 nM, 90 nM and 49 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively. Antiproliferative and antineoplastic activity .

HY-163001

Microcolin H	Autophagy p62 Atg8/LC3	Cancer
Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models .

HY-P99506

Tamrintamab SC-003 mAb; SC-Mab003; SC34.28ss1	ADC Antibody	Cancer
Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 (DPEP3 or MBD3). DPEP3 is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research .

HY-P1045

187-1, N-WASP inhibitor 1 Publications Verification	Arp2/3 Complex	Others
187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

HY-P1045A

187-1, N-WASP inhibitor TFA	Arp2/3 Complex	Others
187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

HY-124187

Pinolenic acid ethyl ester Ethyl pinolenate	Biochemical Assay Reagents	Others
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

Pinolenic acid ethyl ester Ethyl pinolenate	Biochemical Assay Reagents
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

Phosphatidylinositol phosphodiesterase	Biochemical Assay Reagents
Phosphatidylinositol phosphodiesterase hydrolyzes phosphatidylinositol to diacylglycerols and a mixture of myoinositol 1- and 1, 2-cyclic phosphates .

Cat. No.	Product Name	Target	Research Area

HY-P1045

187-1, N-WASP inhibitor 1 Publications Verification	Arp2/3 Complex	Others
187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

HY-P2856

Phosphatidylinositol phosphodiesterase	Endogenous Metabolite	Metabolic Disease
Phosphatidylinositol phosphodiesterase hydrolyzes phosphatidylinositol to diacylglycerols and a mixture of myoinositol 1- and 1, 2-cyclic phosphates .

HY-P1834

MARCKS Peptide(151-175), Phosphorylated	Peptides	Inflammation/Immunology
MARCKS Peptide(151-175), Phosphorylated is a phosphorylated peptide corresponding to the basic effector domain of myristoylated alanine-rich protein kinase C substrate protein (MARCKS). Phosphorylation of MARCKS Peptide (151-175) reverses its inhibition of phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) .

HY-163001

Microcolin H	Autophagy p62 Atg8/LC3	Cancer
Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models .

HY-P1045A

187-1, N-WASP inhibitor TFA	Arp2/3 Complex	Others
187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-114457

Phosphatidylinositol 4,5-bisphosphate L-alpha-phosphatidylinositol-4,5-bisphosphate	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	PI3K
Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger .

HY-163001

Microcolin H	Microorganisms Source classification	Autophagy p62 Atg8/LC3
Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models .

Species:	Human (7)
Tag:	His (6) Tag Free (1) GST (3)
Source:	HEK293 (1) Sf9 insect cells (3) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P700597

	PIP4K2B Protein, Human (His) PIP4K2B; phosphatidylinositol-5-phosphate 4-kinase, type II, beta; phosphatidylinositol 4 phosphate 5 kinase, type II, beta , PIP5K2B; phosphatidylinositol-5-phosphate 4-kinase type-2 beta; PIP5KIIB; PIP5KIIbeta; PIP4KII-beta; PTDINS(4)P-5-kinase; PI(5)P 4-kinase type II beta; diphosphoinositide kinase 2-beta; ptdIns(5)P-4-kinase isoform 2-beta; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; phosphatidylinositol-4-phosphate 5-kinase, type II, beta; PI5P4KB; PIP5K2B	Human	E. coli
	PIP4K2B Protein actively synthesizes phosphatidylinositol 4,5-bisphosphate, preferring GTP over ATP in PI(5)P phosphorylation, with enzymatic activity linked to physiological GTP levels. Its unique GTP-sensing ability critically aids metabolic adaptation. PIP4K2B, part of PIP4Ks, negatively influences insulin signaling via a catalytic-independent mechanism, interacting with PIP5Ks to suppress PIP5K-mediated PtdIns(4,5)P2 synthesis, hindering insulin-dependent conversion to PtdIns(3,4,5)P3. This multifaceted role emphasizes PIP4K2B's significance in modulating key signaling pathways for cellular homeostasis and metabolic responsiveness. PIP4K2B Protein, Human (His) is the recombinant human-derived PIP4K2B protein, expressed by E. coli, with N-10*His labeled tag. The total length of PIP4K2B Protein, Human (His) is 415 a.a., with molecular weight of 53.3 kDa.

HY-P701750

	PIP4K2C Protein, Human PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; phosphatidylinositol 5-phosphate 4-kinase type II gamma; PI(5)P 4-kinase type II gamma; PIP4KII-gamma	Human	E. coli
	PIP4K2C protein is a low-activity phosphatidylinositol 5-phosphate 4-kinase that functions as a GTP sensor, and its GTP-dependent kinase activity is higher than ATP-dependent activity. In addition to its catalytic role, PIP4K2C independently negatively regulates insulin signaling by interacting with PIP5K and inhibits PIP5K-mediated PtdIns(4,5)P2 synthesis. PIP4K2C Protein, Human is the recombinant human-derived PIP4K2C protein, expressed by E. coli , with tag free. The total length of PIP4K2C Protein, Human is 420 a.a., .

HY-P71207

	PITPNA Protein, Human (His) phosphatidylinositol Transfer Protein Alpha Isoform; PI-TP-Alpha; PtdIns Transfer Protein Alpha; PtdInsTP Alpha; PITPNA; PITPN	Human	E. coli
	PITPNA Protein catalyzes phosphatidylinositol (PI) and phosphatidylcholine (PC) transfer between membranes, displaying a preference for shorter saturated or monosaturated acyl chains at sn-1 and sn-2 positions. For PC, the preference order is C16:1 > C16:0 > C18:1 > C18:0 > C20:4, and for PI, it is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3. PITPNA Protein, Human (His) is the recombinant human-derived PITPNA protein, expressed by E. coli , with N-6*His labeled tag. The total length of PITPNA Protein, Human (His) is 270 a.a., with molecular weight of 16 & 22 & 38 kDa, respectively.

HY-P71206

	PIP4K2A Protein, Human (HEK293, His) 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; PIP5KIII; phosphatidylinositol 5-phosphate 4-kinase type II alpha; PtdIns(4)P-5-kinase B isoform; PtdIns(4)P-5-kinase C isoform; PtdIns(5)P-4-kinase isoform 2-alpha	Human	HEK293
	The PIP4K2A protein phosphorylates phosphatidylinositol 5-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP4K2A Protein, Human (HEK293, His) is the recombinant human-derived PIP4K2A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PIP4K2A Protein, Human (HEK293, His) is 406 a.a., with molecular weight of 52-58 kDa.

HY-P701752

	PK3C3 Protein, Human (Sf9, His, GST) PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3; PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34	Human	Sf9 insect cells
	The PI3KC3 protein is the catalytic subunit of the PI3K complex and mediates the formation of phosphatidylinositol 3-phosphate. PI3KC3-C1 initiates autophagosomes, whereas PI3KC3-C2 promotes autophagosome maturation and endocytosis. PK3C3 Protein, Human (Sf9, His, GST) is the recombinant human-derived PK3C3 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of PK3C3 Protein, Human (Sf9, His, GST) is 886 a.a., .

HY-P701744

	PIK3R3 Protein, Human (Sf9, His, GST) PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma; PI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma; p55PIK	Human	Sf9 insect cells
	PIK3R3 protein, through its SH2 domain, interacts with phosphorylated protein-tyrosine kinases, crucially regulating their kinase activity. During insulin stimulation, PIK3R3 binds to IRS-1. Operating as a heterodimer with a p110 catalytic subunit, it interacts with AXL, expanding its functional network. PIK3R3 Protein, Human (Sf9, His, GST) is the recombinant human-derived PIK3R3 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of PIK3R3 Protein, Human (Sf9, His, GST) is 460 a.a., .

HY-P701742

	PI4KB Protein, Human (Sf9, His, GST) PI4KB; phosphatidylinositol 4-kinase beta; PI4K-beta; PI4Kbeta; PtdIns 4-kinase beta; NPIK; PI4K92; PI4KIII	Human	Sf9 insect cells
	The PI4KB protein is a key enzyme that initiates the production of 1,4,5-trisphosphate inositol (PIP) by phosphorylating phosphatidylinositol (PI). In addition to myo-inositol signaling, it is involved in mitotic Golgi disassembly and Golgi-to-plasma membrane trafficking, which is critical for cell membrane dynamics. PI4KB Protein, Human (Sf9, His, GST) is the recombinant human-derived PI4KB protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of PI4KB Protein, Human (Sf9, His, GST) is 815 a.a., .

Cat. No.	Product Name	Chemical Structure

HY-146949S

D-Myo-phosphatidylinositol diC16-d5

D-Myo-phosphatidylinositol diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol diC16.
HY-146947S

D-Myo-phosphatidylinositol 4-phosphate diC16-d5

D-Myo-phosphatidylinositol 4-phosphate diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol 4-phosphate diC16.
HY-146948S

D-Myo-phosphatidylinositol 4,5-bisphosphate diC16-d5

D-Myo-phosphatidylinositol 4,5-bisphosphate diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol 4,5-bisphosphate diC16.
HY-146946S

D-Myo-phosphatidylinositol 3,4,5-trisphosphate diC16-d5

D-Myo-phosphatidylinositol 3,4,5-trisphosphate diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol 3,4,5-trisphosphate diC16.

Cat. No.	Product Name	Application	Reactivity

HY-P80868

PI3 Kinase p85 beta Antibody (YA688) p85; p85 beta; p85-BETA; P85B; P85B_HUMAN; phosphatidylinositol 3 kinase; phosphatidylinositol 3 kinase regulatory beta subunit; phosphatidylinositol 3 kinase regulatory subunit beta; phosphatidylinositol 3 kinase regulatory subunit polypeptide 2; Phospha	WB	Human, Mouse, Rat
PI3 Kinase p85 beta Antibody (YA688) is a non-conjugated and Mouse origined monoclonal antibody about 82 kDa, targeting to PI3 Kinase p85 beta (8D9). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P81872

PI3 Kinase p110 delta Antibody (YA1617) PIK3CD; phosphatidylinositol 4; 5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3-kinase subunit delta; PI3K-delta; PI3Kdelta; PtdIns-3-kinase subunit delta; phosphatidylinositol 4; 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; PtdIns-3-kinase subunit p110-delta; p110delta	WB, ICC/IF	Human, Mouse, Rat

HY-P81162

PIK3CA Antibody PI3 kinase p110 subunit alpha; caPI3K; MGC142161; MGC142163; p110 alpha; phosphatidylinositol 3 kinase catalytic alpha polypeptide; phosphatidylinositol 3 kinase catalytic 110 KD alpha; phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform; Phosphoinositide 3 kinase catalytic alpha polypeptide; PI3 kinase p110 subunit alpha; PI3K; PI3KC A; PIK3C A; PK3CA; PtdIns 3 kinase p110; PI3-kinase P110α; PI3-kinase p110 subunit alpha; PI 3 Kinase catalytic subunit alpha; PK3CA_HUMAN; PI3 kinase P110α.	WB; ELISA; IHC-P; IHC-F; ICC; IF	Human, Mouse, Rat(predicted: Chicken, Cow, Rabbit)
PIK3CA Antibody is an unconjugated, approximately 117 kDa, rabbit-derived, anti-PIK3CA polyclonal antibody. PIK3CA Antibody can be used for: WB, ELISA, IHC-P, IHC-F, ICC, IF expriments in human, mouse, rat, and predicted: chicken, cow, rabbit background without labeling.

HY-P81229

PI3 Kinase p110 beta Antibody PI3-kinase p110 subunit beta; p110 BETA; p110Beta; PI3K beta; phosphatidylinositol 3 kinase catalytic beta polypeptide; phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit beta; phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit beta isoform; phosphatidylinositol-4; Phosphoinositide 3 kinase catalytic beta polypeptide; PI3 kinase p110 subunit beta; PI3-kinase subunit beta; PI3K; PI3K beta; PI3K-beta; PI3Kbeta; PI3KCB; PIK3C1; Pik3cb; PK3CB_HUMAN; PtdIns 3 kinase p110; PtdIns-3-kinase subunit beta; PtdIns-3-kinase subunit p110-beta; 5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; 5-bisphosphate 3-kinase catalytic subunit beta isoform.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; ICC; IF	Human, Mouse, Rat(predicted: Dog, Cow, Horse, Rabbit)
PI3 Kinase p110 beta Antibody is an unconjugated, approximately 123 kDa, rabbit-derived, anti-PI3 Kinase p110 beta polyclonal antibody. PI3 Kinase p110 beta Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, and predicted: dog, cow, horse, rabbit background without labeling.

HY-P81199

phospho-PI3KCA (Tyr317) Antibody PIK3CA(phospho Y317); PI3 kinase p110 subunit alpha; caPI3K; MGC142161; MGC142163; p110 alpha; phosphatidylinositol 3 kinase catalytic alpha polypeptide; phosphatidylinositol 3 kinase catalytic 110 KD alpha; phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform; Phosphoinositide 3 kinase catalytic alpha polypeptide; PI3 kinase p110 subunit alpha; PI3K; PI3KC A; PIK3C A; PIK3CA; PK3CA; PtdIns 3 kinase p110; PI3-kinase P110α; PI3-kinase p110 subunit alpha; PI 3 Kinase catalytic subunit alpha; PK3CA_HUMAN; PI3 kinase P110α.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse(predicted: Rat)
phospho-PI3KCA (Tyr317) Antibody is an unconjugated, approximately 117 kDa, rabbit-derived, anti-phospho-PI3KCA (Tyr317) polyclonal antibody. phospho-PI3KCA (Tyr317) Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, and predicted: rat background without labeling.

HY-P81211

phospho-PI3 Kinase p110 beta (Ser1070) Antibody PI3-kinase p110 subunit beta; p-PI3Kβ(Ser1070); PI 3-kinase C2β; p110 BETA; p110Beta; phosphatidylinositol 3 kinase catalytic beta polypeptide; phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit beta; phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit beta isoform; phosphatidylinositol-4; Phosphoinositide 3 kinase catalytic beta polypeptide; PI3 kinase p110 subunit beta; PI3-kinase subunit beta; PI3K; PI3K beta; PI3K-beta; PI3Kbeta; PI3KCB; PIK3C1; Pik3cb; PK3CB_HUMAN; PtdIns 3 kinase p110; PtdIns-3-kinase subunit beta; PtdIns-3-kinase subunit p110-beta; 5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; 5-bisphosphate 3-kinase catalytic subunit beta isoform.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse, Rat(predicted: Chicken, Dog, Pig, Cow, Horse, Guinea Pig)
phospho-PI3 Kinase p110 beta (Ser1070) Antibody is an unconjugated, approximately 110-123 kDa, rabbit-derived, anti-phospho-PI3 Kinase p110 beta (Ser1070) polyclonal antibody. phospho-PI3 Kinase p110 beta (Ser1070) Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, and predicted: chicken, dog, pig, cow, horse, guinea pig background without labeling.

HY-P80867

PI3 Kinase p85 alpha Antibody (YA689) PIK3R1; GRB1; phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s	WB, IHC-P	Human, Mouse, Rat
PI3 Kinase p85 alpha Antibody (YA689) is a non-conjugated and Mouse origined monoclonal antibody about 84 kDa, targeting to PI3 Kinase p85 alpha (1C8). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P83087

SHIP1 Antibody (YA2832) INPP5D; SHIP; SHIP1; phosphatidylinositol 3; 4; 5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SHIP-1	WB, IHC-P, IP, FC	Human

HY-P80846

Phospho-PI3 Kinase p85/p55 (Tyr467/Tyr199) Antibody 1 Publications Verification PIK3R1; GRB1; phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s	WB, IHC-F, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat, Monkey
Phospho-PI3 Kinase p85/p55 (Tyr467/Tyr199) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 84 kDa, targeting to Phospho-PI3 Kinase p85/p55 (Tyr467/Tyr199). It can be used for WB,IHC-F,IHC-P,ICC/IF,ELISA assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P83344

Phospho-SHIP1 (Tyr1020) Antibody (YA3089) INPP5D; SHIP; SHIP1; phosphatidylinositol 3; 4; 5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SHIP-1	WB, ICC/IF, IP	Human

HY-P83044

PIK3C3 Antibody (YA2789) phosphatidylinositol 3-kinase catalytic subunit type 3 (EC:2.7.1.137); PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34; VPS34 antibodyPIK3C3；	WB, IHC-P	Human, Mouse, Rat

HY-P82949

Phospholipase C beta 3 Antibody (YA2694) PLCB3; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase beta-3; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3	WB, IHC-P	Human

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