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polar

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60

Inhibitors & Agonists

3

Screening Libraries

17

Fluorescent Dye

12

Biochemical Assay Reagents

1

Peptides

11

Natural
Products

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116425
    N-1-Naphthylphthalamic acid

    Alanap 1

    		 Others Others
    N-1-Naphthylphthalamic acid (Alanap 1) is a modulator of polar auxin transport that competes with auxin (indole-3-acetic acid, IAA) for membrane binding sites. N-1-Naphthylphthalamic acid also disrupts maize leaf initiation, KNOX protein regulation, and leaf margin formation .
    N-1-Naphthylphthalamic acid
  • HY-B2246
    L-Carnitine hydrochloride
    5+ Cited Publications

    (R)-Carnitine hydrochloride; Levocarnitine hydrochloride

    		 Endogenous Metabolite Metabolic Disease Cancer
    L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .
    L-Carnitine hydrochloride
  • HY-115756
    4-Maleimidosalicylic acid

    		Others Others
    4-Maleimidosalicylic acid is a polar maleimide, and does not suppress IL-2 production in JURKAT T cells .
    4-Maleimidosalicylic acid
  • HY-157950
    DSPE-PEG2000-triGalNAc ammonium

    		Liposome Cancer
    DSPE-PEG2K-triGalNAc is a polar lipid composed of DSPE and tri-N-acetylgalactosamine that can be used to construct liposomes target to asialoglycoprotein receptor (ASGPR).
    DSPE-PEG2000-triGalNAc ammonium
  • HY-N12540
    Monogalactosyldiacylglycerol

    MGDG

    		 Others Others
    Monogalactosyldiacylglycerol (MGDG) is a polar lipid that does not form a bilayer and is found, for example, in the chloroplast thylakoid of aerobic photosynthetic organisms. Monogalactosyldiacylglycerol lacks charge and is highly unsaturated, which provides a fluid environment that facilitates the diffusion process of electron transfer in photosynthesis and may be used in the packaging of natural proteins. The galactolipid Monogalactosyldiacylglycerol has anti-inflammatory effects in vivo ..
    Monogalactosyldiacylglycerol
  • HY-D1767
    Tempocholine

    		Fluorescent Dye Others
    Tempocholine is a polar tracer.
    Tempocholine
  • HY-21226
    Levoglucosenone

    Levoglucosenone Levoglucosenone has unique chemical properties that make it an important intermediate in the production of a wide variety of chemicals, including pharmaceuticals, fragrances and flavorings. Due to its ability to dissolve polar and non-polar compounds, it can also be used as a solvent or fuel additive.
    Levoglucosenone
  • HY-117289
    AKOS B018304

    		Others Others
    AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position.
    AKOS B018304
  • HY-D1754
    Lucifer yellow CH ammonium

    LYCH ammonium

    		 Fluorescent Dye Others
    Lucifer yellow CH (LYC) ammonium is a thiol-reactive fluorescent polar tracer.
    Lucifer yellow CH ammonium
  • HY-N4254
    Distearoylphosphatidylserine

    DSPS

    		 Liposome Metabolic Disease
    Distearoylphosphatidylserine (DSPS) acts as a monolayer. Phosphatidylserine is a phospholipid with a polar serine found in phosphoester linkage to diacylglycerol .
    Distearoylphosphatidylserine
  • HY-Y0873L
    PEG800

    Polyethylene glycol 800

    		 Biochemical Assay Reagents Others
    PEG800 (Polyethylene glycol 800) is a nonionic surfactant that is soluble in water and many polar solvents .
    PEG800
  • HY-133803
    Z-Ala-Ala-OH

    		Amino Acid Derivatives Others
    Z-Ala-Ala-OH is a non-polar amino acid that can be used in enzymatic peptide synthesis .
    Z-Ala-Ala-OH
  • HY-113116
    Sphinganine 1-phosphate

    D-erythro-Dihydrosphingosine 1-phosphate

    		 Endogenous Metabolite Inflammation/Immunology Cancer
    Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiological processes .
    Sphinganine 1-phosphate
  • HY-124190
    Isopropyl myristate

    		Others Others
    Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate (IPM) is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired .
    Isopropyl myristate
  • HY-D1777
    Pyrromethene 605

    PM605

    		 Fluorescent Dye Others
    Pyrromethene 605 (PM605) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
    Pyrromethene 605
  • HY-W248118
    Pyrromethene 556

    PM556

    		 Fluorescent Dye Others
    Pyrromethene 556 (PM556) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
    Pyrromethene 556
  • HY-W248583
    Pyrromethene 650

    PM650

    		 Fluorescent Dye Others
    Pyrromethene 650 (PM650) is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.
    Pyrromethene 650
  • HY-N12551
    2-O-β-D-Glucopyranosylcucurbitacin F 25-acetate

    		Others Others
    2-O-β-D-Glucopyranosylcucurbitacin F 25-acetate is a cucurbitacin glucoside that can isolated from the more polar fractions of the MeOH extract of Cigarrilla mexicana .
    2-O-β-D-Glucopyranosylcucurbitacin F 25-acetate
  • HY-133653
    3,3-Dibromopropenoic acid

    3,3-Dibromoacrylic acid

    		 Others Others
    3,3-Dibromopropenoic acid is a 3,3-dibromo product based on propenoic acid. 3,3-Dibromopropenoic acid is a polar aromatic brominated disinfection byproduct during chlorination in water .
    3,3-Dibromopropenoic acid
  • HY-W020798
    1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine

    		Fluorescent Dye Others
    1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine is a fluorescent probe with a polar phosphatidylethanolamine head group for the determination of surface lipid oxidation in lipoproteins and plasma .
    1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine
  • HY-D0837
    Imidazole
    2 Publications Verification

    Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene

    		 Endogenous Metabolite Others
    Imidazole, a highly polar compound containing planar five-membered rings, has been widely used as a corrosion inhibitor. Derivatives of Imidazole have antimicrobial, anti-inflammatory, and antitumor activities .
    Imidazole
  • HY-124891
    1-Phenylpyrrole

    N-Phenylpyrrole

    		 Others Others
    1-Phenylpyrrole (N-Phenylpyrrole) has dual fluorescent properties. 1-Phenylpyrrole displays a single band in nonpolar solvents and a second red-shifted fluorescent band in polar solvents .
    1-Phenylpyrrole
  • HY-125734
    DMHAPC-Chol

    		Liposome Others
    DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .
    DMHAPC-Chol
  • HY-N4275
    Oleaside A

    		Others Cancer
    Oleaside A is a polar cardenolide monoglycoside isolated from Nerium oleander, inhibits the induction of ICAM-1 induced by IL-1α and TNF-α, and has anti-tumor activity .
    Oleaside A
  • HY-Y1275
    N-Methylpyrrolidone

    NMP
    N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an organic polar solvent. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals .
    N-Methylpyrrolidone
  • HY-D1757
    Lucifer yellow ethylenediamine

    LYen; PAsp- LY

    		 Fluorescent Dye Others
    Lucifer yellow ethylenediamine (LYen; PAsp- LY) is a polar tracer that can be coupled with aldehydes and ketones to form Schiff bases, which can be reduced to stable amine derivatives by sodium borohydride (NaBH4) or sodium cyanide borohydride (NaCNH3).
    Lucifer yellow ethylenediamine
  • HY-113116S
    Sphinganine 1-phosphate-d7

    		Isotope-Labeled Compounds Endogenous Metabolite Inflammation/Immunology Cancer
    Sphinganine 1-phosphate-d7 is deuterium labeled Sphinganine 1-phosphate. Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiologic
    Sphinganine 1-phosphate-d7
  • HY-W115738
    PAR

    		Biochemical Assay Reagents Others
    PAR is an azo dye widely used as a colorimetric reagent for metal ions. PAR forms stable chelates with different metal ions. PAR can also complex with heavy metal ions in polar organic solvent like ethanol .
    PAR
  • HY-N2687
    5-n-Tricosylresorcinol

    		Others Others
    5-n-Tricosylresorcinolthe is the first cyst lipid. 5-n-Tricosylresorcinolthe has metahydroxyl group which allows it to self-associate forming a staggered-chain conformation in which the polar head groups have heaxagonal symmetry .
    5-n-Tricosylresorcinol
  • HY-D1745
    Liptracker-Green

    fac-[Re(CO)3(phen)L]

    		 Fluorescent Dye Others
    Liptracker-green (fac-[Re(CO)3(phen)L]) is a cell-permeable fluorogenic probe that localizes to polar lipids, and can be used to label lipid droplets and other high lipid-content compartments in live and fixed cells using fluorescent microscopy.
    Liptracker-Green
  • HY-112076
    Atropine methyl bromide

    Methylatropine bromide

    		 mAChR Neurological Disease
    Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine .
    Atropine methyl bromide
  • HY-133654
    2,3,3-Tribromopropenoic acid

    		Others Others
    2,3,3-Tribromopropenoic acid is a 2,3,3-Tribromo product based on propenoic acid. 2,3,3-Tribromopropenoic acid is a polar aromatic brominated disinfection byproduct during chlorination in water and shows cytotoxic potency in mammalian cell chronic cytotoxicity experiments .
    2,3,3-Tribromopropenoic acid
  • HY-N10510
    Blood group A antigen tetraose type 5

    A-Tetrasaccharide

    		 Others Others
    Blood group A antigen tetraose type 5 (A-Tetrasaccharide) is a tetrasaccharide and a blood group specific oligosaccharide, inhibits the binding of anti-A antibody to blood group A substance. Blood group A antigen tetraose type 5 can be isolated from polar bear milk samples .
    Blood group A antigen tetraose type 5
  • HY-Y0320
    Dimethyl sulfoxide
    Maximum Cited Publications
    89 Publications Verification

    DMSO
    Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
    MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).
    Dimethyl sulfoxide
  • HY-D1672
    TMR Biocytin

    		Fluorescent Dye Neurological Disease
    TMR Biocytin is a polar tracer used in the research of cell-cell and cell-liposome fusions, as well as membrane permeability and cellular uptake during pinocytosis. TMR Biocytin can be detected using streptavidin, and is an effective neuronal tracer in live tissue (Ex=544 nm, Em=571 nm) .
    TMR Biocytin
  • HY-W440683
    C13-112-tetra-tail

    		Liposome Others
    C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).
    C13-112-tetra-tail
  • HY-W440681
    C13-112-tri-tail

    		Liposome Others
    C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
    C13-112-tri-tail
  • HY-W440684
    C13-113-tetra-tail

    		Liposome Others
    C13-113-tetra tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tetra tail can be formulated into a lipid nanoparticle (LNP).
    C13-113-tetra-tail
  • HY-W440682
    C13-113-tri-tail

    		Liposome Others
    C13-113-tri tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tri tail can be formulated into a lipid nanoparticle (LNP).
    C13-113-tri-tail
  • HY-Y1275S1
    N-Methyl-2-pyrrolidone-d3

    		Isotope-Labeled Compounds Others
    N-Methyl-2-pyrrolidone-d3 is the deuterium labeled N-Methylpyrrolidone[1]. N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an organic polar solvent. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals[2][3].
    N-Methyl-2-pyrrolidone-d3
  • HY-W587663
    4′-DTMP

    		Dihydrofolate reductase (DHFR) Infection
    4 '-DTMP is a DHFR inhibitor with Ki of 5.1 nM (DHFR WT) and 34.3 nM (DHFR L28R), respectively. 4 '-DTMP carries a polar modification that induces additional local interactions with the enzyme. In particular, the hairpin structure on the M20 ring is related to the internal communication of the DHFR. 4 '-DTMP has potential inhibition of E.coli .
    4′-DTMP
  • HY-B0399
    L-Carnitine
    5+ Cited Publications

    (R)-Carnitine; Levocarnitine

    		 Endogenous Metabolite Neurological Disease Cancer
    L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .
    L-Carnitine
  • HY-101461
    Methyl-β-cyclodextrin
    40+ Cited Publications

    Methyl-beta-cyclodextrin

    		 Biochemical Assay Reagents Cancer
    Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .
    Methyl-β-cyclodextrin
  • HY-D0041
    Calcein-AM
    35+ Cited Publications

    Calcein acetoxymethyl ester

    		 Fluorescent Dye Cancer
    Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
    Calcein-AM
  • HY-123622
    CYMAL-5

    		Biochemical Assay Reagents Others
    CYMAL-5 is a cycloalkyl aliphatic saccharide. CYMAL-5 is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5 is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .
    CYMAL-5
  • HY-Y0415
    Tetraethylammonium (fluoride)

    N,N,N-triethylethanaminium (fluoride)
    Tetraethylammonium fluoride is an organic compound containing both ammonium and fluorine functional groups. It is commonly used as a reagent in various chemical synthesis applications, especially as a source of fluoride ions for nucleophilic reactions. Tetraethylammonium fluoride has several properties that make it suitable for these applications, including its high solubility in polar solvents and its ability to selectively activate certain chemical bonds. In addition, it is used as a catalyst for organic reactions and as a surfactant in the production of semiconductors and microelectronics.
    Tetraethylammonium (fluoride)
  • HY-Y0971
    Tetrabutylammonium (fluoride)

    TBAF

    		 Biochemical Assay Reagents Others
    Tetrabutylammonium fluoride is an organic compound containing both ammonium and fluorine functional groups. It is commonly used as a reagent in various chemical synthesis applications, especially as a source of fluoride ions for nucleophilic reactions. Tetrabutylammonium fluoride has several properties that make it suitable for these applications, including its high solubility in polar solvents and its ability to selectively activate certain chemical bonds. In addition, it can be used as a catalyst for organic reactions and as an electrolyte for batteries.
    Tetrabutylammonium (fluoride)
  • HY-N11526
    3-Hydroxy-2-(palmitoyloxy)propyl stearat

    		Others Inflammation/Immunology
    3-Hydroxy-2-(palmitoyloxy)propyl stearat is a non-volatile compound. 3-Hydroxy-2-(palmitoyloxy)propyl stearat can be isolated from less polar fractions of the brown macroalga Fucus virsoides J. Agardh. This part of the substance has a good ability to scavenge free radicals and has a protective effect on the oxidative stress induced by hydrogen peroxide in zebrafish embryos .
    3-Hydroxy-2-(palmitoyloxy)propyl stearat
  • HY-B2246S
    L-Carnitine-d9 chloride

    (R)-Carnitine-d9 (chloride); Levocarnitine-d9 (chloride)

    		 Endogenous Metabolite Metabolic Disease
    L-Carnitine-d9 (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].
    L-Carnitine-d9 chloride
  • HY-W008566
    Norharmane

    Norharman; β-Carboline

    		 Monoamine Oxidase Endogenous Metabolite Infection Neurological Disease Cancer
    Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .
    Norharmane

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