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Inhibitors & Agonists


MCE Kits



Cat. No. Product Name Target Research Areas
  • HY-106681

    Fungichromin; Pentamycin; Cogomycin

    Antibiotic Fungal Cancer
    Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to drug resistance.
  • HY-112663

    Antibiotic Infection
    Monazomycin is a polyene-like antibiotic produced by Streptomyces. Monazomycin molecular weight is about 1200.
  • HY-B0221
    Amphotericin B

    Fungal Antibiotic Infection
    Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
  • HY-B0221A
    Amphotericin B trihydrate

    Antibiotic Fungal Infection Inflammation/Immunology
    Amphotericin B trihydrate, a polyene antibiotic, is first isolated from fermenter cultures of Streptomyces nodosus. Amphotericin B trihydrate also possesses antileishmanial activity.
  • HY-135327
    Amphotericin B methyl ester

    HIV Fungal Infection
    Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disrupts HIV-1 particle production and potently inhibits HIV-1 replication.
  • HY-17409

    Fungal Antibiotic Apoptosis Infection
    Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion. Nystatin is a cholesterol-sequestering agent, partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis.