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Pathways Recommended:	Metabolic Enzyme/Protease

Results for "

protease

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ClpP (7) HCV Protease (30) HIV Protease (79) Protease Activated Receptor (PAR) (43) Ser/Thr Protease (59) Virus Protease (36) ADAMTS (1) ADC Linker (2) Amino Acid Derivatives (1) Amyloid-β (1) Angiotensin-converting Enzyme (ACE) (2) Antibiotic (3) Antibody-Drug Conjugates (ADCs) (3) Apoptosis (39) Atg4 (2) Aurora Kinase (3) Autophagy (13) Bacterial (16) Bcl-2 Family (1) Beta-lactamase (1) Beta-secretase (2) Biochemical Assay Reagents (5) Bradykinin Receptor (1) Carbonic Anhydrase (1) Carboxypeptidase (1) Caspase (5) Cathepsin (29) CCR (1) CDK (2) Ceramidase (1) Complement System (3) COX (1) Cytochrome P450 (6) Dengue virus (8) Deubiquitinase (25) Dipeptidyl Peptidase (3) DNA Methyltransferase (1) DNA Stain (1) DNA/RNA Synthesis (7) Drug Metabolite (3) Drug-Linker Conjugates for ADC (2) E1/E2/E3 Enzyme (5) EBV (1) Elastase (4) Endogenous Metabolite (17) Enterovirus (2) Epigenetic Reader Domain (2) Eukaryotic Initiation Factor (eIF) (1) FAAH (1) Factor Xa (10) Fatty Acid Synthase (FASN) (2) Filovirus (1) Flavivirus (11) Fluorescent Dye (20) Free Fatty Acid Receptor (1) Fungal (2) Glucosidase (1) Glutathione Peroxidase (1) HCV (21) HIF/HIF Prolyl-Hydroxylase (1) HIV (55) HMG-CoA Reductase (HMGCR) (1) HPV (1) HSV (4) IKK (1) Indoleamine 2,3-Dioxygenase (IDO) (3) Influenza Virus (2) Isotope-Labeled Compounds (19) Legumain (1) Liposome (6) MALT1 (17) MDM-2/p53 (2) Microtubule/Tubulin (1) Mitochondrial Metabolism (2) MMP (4) NF-κB (4) Nucleoside Antimetabolite/Analog (1) P-glycoprotein (5) PAI-1 (8) Parasite (14) PKC (2) Potassium Channel (1) PROTACs (5) Proteasome (10) Ras (1) Renin (3) Reverse Transcriptase (1) SARS-CoV (136) Separase (1) Small Interfering RNA (siRNA) (2) Thrombin (10) TNF Receptor (3) Topoisomerase (1) TRP Channel (1) γ-secretase (2)
By Research Areas:	Cancer (148) Cardiovascular Disease (41) Endocrinology (3) Infection (289) Inflammation/Immunology (100) Metabolic Disease (31) Neurological Disease (22)
Click Chemistry:	Alkynes (1)

586

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

132

Peptides

MCE Kits

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201

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Isotope-Labeled Compounds

Antibodies

Click Chemistry

Protease-Activated Receptor-2, amide 2 Publications Verification	Protease Activated Receptor (PAR)	Cancer
Protease-Activated Receptor-2, amide (SLIGKV-NH₂) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.

Proteinase K 5 Publications Verification protease K	Ser/Thr Protease	Others
Proteinase K (Protease K) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures. Proteinase K can be use for promoting methods of viral nucleic acid extraction, and detection .

Protease-Activated Receptor-4	Protease Activated Receptor (PAR)	Others
Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).

Protease-Activated Receptor-1 antagonist 2	Protease Activated Receptor (PAR)	Cardiovascular Disease
Protease-Activated Receptor-1 antagonist 2 is an orally active protease-activated receptor-1 (PAR-1) antagonist, with an IC₅₀ value of 7 nM. Protease-Activated Receptor-1 antagonist 2 has favorable pharmacokinetic properties which is useful in the research of cardiovascular disease (CVD), such as atherosclerosis and restenosis .

Protease-Activated Receptor-1 antagonist 1	Protease Activated Receptor (PAR)	Cardiovascular Disease
Protease-Activated Receptor-1 antagonist 1 (Compound 13) is a protease-activated receptor-1 (PAR-1) antagonist with the IC₅₀ of 3 nM by FLIPR technology. Protease-Activated Receptor-1 antagonist 1 can be used for the research of thrombotic cardiovascular, myocardial infarction, and peripheral arterial disease .

Protease-Activated Receptor-1 antagonist 3	Protease Activated Receptor (PAR)	Cardiovascular Disease
Protease-Activated Receptor-1 antagonist 3 is a potent protease-activated receptor-1 antagonist with an IC₅₀ value of 7 nM. Protease-Activated Receptor-1 antagonist 3 shows binding affinity for hERG K ⁺ channel with an IC₅₀ value of 9 µM .

SLIGRL-NH2 protease-Activated Receptor-2 Activating Peptide	Protease Activated Receptor (PAR)	Inflammation/Immunology
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2) .

SLIGRL-NH2 TFA protease-Activated Receptor-2 Activating Peptide TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
SLIGRL-NH2 TFA (Protease-Activated Receptor-2 Activating Peptide TFA) is an agonist of Protease-Activated Receptor-2 (PAR-2) .

Protease-Activated Receptor-1, PAR-1 Agonist	Protease Activated Receptor (PAR)	Inflammation/Immunology
Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor .

Protease-Activated Receptor-1, PAR-1 Agonist TFA	Protease Activated Receptor (PAR)	Cancer
Protease-Activated Receptor-1, PAR-1 Agonist TFA is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist TFA corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor .

Protease-Activated Receptor-3 (PAR-3) (1-6), human	Protease Activated Receptor (PAR)	Inflammation/Immunology
Protease-Activated Receptor-3 (PAR-3) (1-6), human is a proteinase-activated receptor (PAR-3) agonist peptide .

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a proteinase-activated receptor (PAR-3) agonist peptide .

Recombinant Kex2 protease	Ser/Thr Protease	Others
Recombinant Kex2 protease is a membrane-bound, Ca ²⁺-dependent serine protease. Recombinant Kex2 protease specifically recognize and cleave the carboxyl-terminal peptide bonds of dibasic amino acids .

*HIV Protease* Substrate IV**	HIV Protease	Infection
HIV Protease Substrate IV is a substrate of HIV protease. HIV Protease Substrate IV can be used to measure the activity of HIV (human immunodeficiency virus) -1 protease .

*HIV-1 protease-IN-12*	HIV Protease	Infection
HIV-1 protease-IN-12 (compound 35b) is a HIV-1 protease inhibitor with an IC₅₀ of 0.51 nM. HIV-1 protease-IN-12 also inhibits drug-resistant variant .

*HIV Protease* Substrate 1**	HIV Protease	Infection
HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .

*HIV-1 protease-IN-11*	HIV Protease	Infection
HIV-1 protease-IN-11 (compound 34a) is a HIV-1 protease inhibitor with an IC₅₀ of 0.41 nM. HIV-1 protease-IN-11 also exhibits significant activity against drug-resistant variant .

*HIV-1 protease-IN-3*	HIV HIV Protease	Infection
HIV-1 protease-IN-3 (compound 14) is a potent inhibitor of HIV-1 protease (IC₅₀=71 nM; EC₅₀=0.86 μM) .

*HIV-1 protease-IN-1*	HIV	Infection
HIV-1 protease-IN-1 (Compound 1e) is a potent inhibitor of HIV-1 protease with an IC₅₀ of 90 pM. HIV-1 protease-IN-1 demonstrates antiviral activity with EC₅₀ value of 89 nM against B-HIV. HIV-1 protease-IN-1 exhibits activity with EC₅₀ value of 13.59 nM against C-HIV strain ZM246. HIV-1 protease-IN-1 shows remarkable activity with EC₅₀ value of 8.23 nM against C-HIV strain Indie ^[1].

*HIV-1 protease-IN-5*	HIV Protease	Infection
HIV-1 protease-IN-5 (Compound 13c) is a HIV-1 protease inhibitor with an IC₅₀ of 1.64 nM. HIV-1 protease-IN-5 shows remarkable activity against wild-type and DRV-resistant HIV-1 variants .

*HIV Protease* Substrate 1 TFA**	HIV Protease	Infection
HIV Protease Substrate 1 TFA, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .

*Hepatitis Virus C NS3 Protease* Inhibitor 2**	HCV Protease HCV	Infection
Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor of hepatitis C virus (HCV) NS3 protease, with a K_i of 41 nM .

*HIV-1 protease-IN-4*	HIV	Infection
HIV-1 protease-IN-4 (Compound II-22) is a potent HIV-1 protease inhibitor. HIV-1 protease-IN-4 is a proagent of atazanavir. HIV-1 protease-IN-4 as a proagent that delivers the parent 1 to rat plasma with a 5-fold higher AUC and 67-fold higher C24 when compared to oral administration of the parent agent .

*HIV-1 protease-IN-13*	HIV Protease	Infection
HIV-1 protease-IN-13 (compound 18d) is a potent HIV-1 protease inhibitor with an IC₅₀ value of 0.54 nM. HIV-1 protease-IN-13 also shows potent activity against HIV-1DRVRS (DRV-resistant mutation) and HIV-1NL4_3 variant (wild type) .

*HIV-1 protease-IN-8*	HIV Protease	Infection
HIV-1 protease-IN-8 (compound 34b) is a potent HIV-1 protease inhibitor with an IC₅₀ value of 0.32 nM. HIV-1 protease-IN-8 displays IC₅₀s of 0.29 μM and 1.90 μM for wild-type HIV-1 (HIV-1_NL4-3) and drug-resistant variant (HIV-1_MDR), respectively. HIV-1 protease-IN-8 displays robust antiviral activity against both wild-type HIV-1 and drug-resistant variant .

*Cysteine Protease* inhibitor** 3 Publications Verification	Cathepsin	Others
Cysteine Protease inhibitor is an inhibitor of cysteine protease.

*Cysteine Protease* inhibitor hydrochloride** 3 Publications Verification	Cathepsin	Others
Cysteine Protease inhibitor hydrochloride is an inhibitor of cysteine protease.

*HIV Protease* Substrate I**	HIV Protease	Infection
HIV Protease Substrate I is a chromogenic substrate of HIV-1 protease. HIV Protease Substrate I has the cleavage site of HIV protease .

Glutamic acid protease	Endogenous Metabolite	Others
Glutamic acid protease only can be found in fungi. Glutamic protease is a proteolytic enzyme containing a glutamic acid residue .

*HIV protease-IN-1*	HIV Protease	Infection
HIV protease-IN-1 (compound 1·succinate) is a potent HIV protease non-peptidic inhibitor, can be used to research AIDS .

*HIV-1 protease-IN-9*	HIV Protease	Infection
HIV-1 protease-IN-9 (compound 5b) is a HIV-1 protease inhibitor, with a K_i of 0.028 nM. HIV-1 protease-IN-9 shows potent antiviral activity, with an IC₅₀ of 66.8 nM .

*Cysteine protease* inhibitor-3**	Parasite	Infection
Cysteine protease inhibitor-3 (Compound 15) is a Cysteine protease inhibitor. Cysteine protease inhibitor-3 inhibits Pf3D7, PfW2, PfFP2 and PfFP3 with IC₅₀s of 0.74 μM, 1.05 μM, 3.5 μM, and 4.9 μM, respectively. Cysteine protease inhibitor-3 has anti-plasmodial efficacy against both drug-sensitive and drug-resistant parasites .

*HIV-1 protease-IN-2*	HIV Protease	Infection
HIV-1 protease-IN-2 is a potent HIV-1 protease inhibitor with an IC₅₀ of 2.53 nM. HIV-1 protease-IN-2 shows antiviral activity against DRV (Darunavir)-sensitive or DRV-resistant HIV-1 variants .

*HIV-1, HIV-2 Protease* Substrate**	HIV Protease	Infection
HIV-1, HIV-2 Protease Substrate is the substrate of HIV-1, HIV-2 protease. And there are 4 residues for conservative substitutions of the substrate binding residues of HIV-1 and *HIV-2 protease* .**

Pepstatin 25+ Cited Publications Pepstatin A	HIV Protease Autophagy	Infection Inflammation/Immunology
Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease .

Pepstatin Trifluoroacetate 25+ Cited Publications Pepstatin A Trifluoroacetate	HIV Protease Autophagy	Infection Inflammation/Immunology
Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Trifluoroacetate also inhibits HIV protease .

Pepstatin acetate Pepstatin A acetate	HIV Protease Autophagy	Infection Inflammation/Immunology
Pepstatin (Pepstatin A) acetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin acetate also inhibits HIV protease .

Pepstatin Ammonium 25+ Cited Publications Pepstatin A Ammonium	HIV Protease Autophagy	Infection Inflammation/Immunology
Pepstatin (Pepstatin A) Ammonium is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Ammonium also inhibits HIV protease .

*HIV-1 protease-IN-6*	HIV Protease HIV	Infection Inflammation/Immunology
HIV-1 protease-IN-6 (compound 17d) is a potent HIV-1 protease inhibitor, with an IC₅₀ of 21 pM and a K_i of 4.7 pM, respectively. HIV-1 protease-IN-6 exhibits potent antiviral activity to DRV (darunavir)-resistant variant, even more than wild type virus .

α-Lytic protease alphaLP	Ser/Thr Protease	Others
α-Lytic protease (alphaLP) is a serine endopeptidase. α-Lytic protease can cleave substrate at the carboxyl terminal side of alanine, serine, threonine, and valine amino acid residues .

*HSV-1 Protease* substrate**	HSV	Infection
HSV-1 Protease substrate is a peptide substrate for HSV-1 (Herpes Simplex Virus Type 1) protease, and the specificity constant (k_cat/K_m) at pH 7.5 for cleavage is 5.2 M ^-1 s ^-1 .

DEPN-8	Dengue virus	Infection
DEPN-8 is a WNV protease substrate. DEPN-8 is used for dengue virus protease inhibitor development .

*HIV-1 protease-IN-7*	HIV Protease	Infection
HIV-1 protease-IN-7 (compound 16) is an orally active HIV-1 protease inhibitor (IC₅₀=3.52 nM, EC₅₀=37 nM) .

*HIV-1 protease-IN-10*	HIV PKC	Infection
HIV-1 protease-IN-10 (Compound 2) has HIV-1 latency reversing activity (IC₅₀: 0.22 μM). HIV-1 protease-IN-10 binds to the PKCδ C1b domain (IC₅₀: 0.69 μM). HIV-1 protease-IN-10 has stability against esterase-mediated hydrolysis .

*Neutral protease, Paenibacillus polymyxa* Dispase II, Dispase	Endogenous Metabolite	Metabolic Disease
Neutral protease, Paenibacillus polymyxa (Dispase II, Dispase) is a neutral protease and potent fibronectinase and type IV collagenase. Neutral protease, Paenibacillus polymyxa can be used to separate the intact epidermis from the dermis and intact epithelial sheets in culture from the substratum .

Leupeptin	Ser/Thr Protease Virus Protease Cathepsin	Infection Inflammation/Immunology
Leupeptin is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin potently inhibits serine, cysteine and threonine proteases. Leupeptin inhibits M ^pro (the main *protease* of SARS-CoV-2) and also has anti-inflammatory activity .

Cat. No.	Product Name

HY-L147

Protease Inhibitor Library

595 Compounds compounds

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. Proteases play important roles in regulating multiple biological processes in all living organisms, such as regulating the fate, localization, and activity of many proteins, modulating protein-protein interactions, creating new bioactive molecules, contributing to the processing of cellular information, and generating, transducing, and amplifying molecular signals.

Proteases are important targets in drug discovery. Some protease inhibitors are often used as anti-virus drugs and anti-cancer drugs. MCE offers a unique collection of 595 protease inhibitors. MCE Protease Inhibitor Library is critical for drug discovery and development.

HY-L012

Metabolism/Protease Compound Library

4515 compounds

Metabolism is the set of life-sustaining chemical reactions in organisms. Metabolic pathways are enzyme-mediated biochemical reactions that lead to biosynthesis (anabolism) or breakdown (catabolism) of natural product small molecules within a cell or tissue. Acting as catalysts, enzymes are crucial to metabolism - they allow a reaction to proceed more rapidly - and they also allow the regulation of the rate of a metabolic reaction. Proteases are used throughout an organism for various metabolic processes. Proteases control a great variety of physiological processes that are critical for life, including the immune response, cell cycle, cell death, wound healing, food digestion, and protein and organelle recycling. Imbalances in metabolic activities have been found to be critical in a number of pathologies, such as cardiovascular diseases, inflammation, cancer, and neurodegenerative diseases.

MCE designs a unique collection of 4515 Metabolism/Protease-related small molecules that act as a useful tool for drug discovery of metabolism-related diseases.

HY-L052

Anti-COVID-19 Compound Library

1485 compounds

COVID-19 poses a serious threat to people's health, and it is urgent to develop drugs to treat COVID-19 quickly. The screening of anti-COVID-19 drugs by using the clinical and approved compounds can greatly shorten the research and development cycle. In addition, the virtual screening technology can effectively narrow the scope of screening and improve the screening efficiency in the pre-screening of new drugs.

Taking advantage of our virtual screening, we conduct virtual screening of approved compound library and clinical compound library based on the 3CL protease (PDB ID: 6LU7), Spike Glycoprotein (PDB ID: 6VSB), NSP15 (PDB ID: 6VWW), RDRP, PLPro and ACE2 (Angiotensin Converting Enzyme 2) structure. We design a unique collection of 1485 compounds which may have anti-COVID-19 activity. Anti-COVID-19 Compound Library will be a powerful tool for screening new anti-COVID-19 activity drugs.

Cat. No.	Product Name	Type

HY-D1080

EDANS 1 Publications Verification 1,5-EDANS	Fluorescent Dyes/Probes
EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET) .

HY-W027544

MCA	Fluorescent Dyes/Probes
MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .

HY-P2065

Ac-VEID-AMC

Fluorescent Dyes/Probes

Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .

HY-148073

MeO-Succ-Arg-Pro-Tyr-AMC	Chromogenic Substrates
MeO-Succ-Arg-Pro-Tyr-AMC is an analogue of 7-amido-4-methylcoumarin (HY-D0027). MeO-Succ-Arg-Pro-Tyr-AMC is a sensitive fluorescent substrate chymotrypsin-like protease. (λ_ex=341 nm, λ_em=441 nm).

HY-W141825

N-Acetyl-DL-phenylalanine β-naphthyl ester	Chromogenic Substrates
N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin .

HY-P2628

Dabcyl-YVADAPV-EDANS	Fluorescent Dyes/Probes
Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K ⁺ deprivation-induced apoptosis of cerebellar granule neurons .

HY-110210

BODIPY-FL NHS ester BODIPY FL,SE	Fluorescent Dyes/Probes
BODIPY-FL NHS ester (BODIPY FL, SE) is an amine-reactive fluorescent probe. The maximum excitation/emission values are 502/511 nm. BODIPY-FL NHS ester can be used to synthesize protease substrates .

HY-P4039

Ac-EEVVAC-pNA	Chromogenic Substrates
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .

HY-134435

Z-Arg-AMC hydrochloride	Fluorescent Dyes/Probes
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .

Cat. No.	Product Name	Type

HY-108717

Proteinase K 5 Publications Verification protease K	Biochemical Assay Reagents
Proteinase K (Protease K) is a nonspecific serine protease that is useful for general digestion of proteins. Proteinase K is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures. Proteinase K can be use for promoting methods of viral nucleic acid extraction, and detection .

HY-P2973

Aspergillopepsin I Aspergillus acid protease	Biochemical Assay Reagents
Aspergillopepsin I (Aspergillus acid protease) is an aspartic endopeptidase that catalyses the hydrolysis of peptide bonds in proteins, with broad specificity .

HY-P1635

Pepsin EC 3.4.23.1	Biochemical Assay Reagents
Pepsin is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin contributes to proteolysis of food proteins in the vertebrate stomach .

HY-P2935

Glutamic acid protease

Biochemical Assay Reagents

Glutamic acid protease only can be found in fungi. Glutamic protease is a proteolytic enzyme containing a glutamic acid residue .

HY-P2990

Enteropeptidase TMPRSS15	Biochemical Assay Reagents
Enteropeptidase (TMPRSS15), a type II transmembrane serine protease and a physiological activator of trypsinogen. Enteropeptidase is associated with the brush border membrane (BBM) of the enterocytes in the upper small intestine. Trypsinogen is the primary substrate for Enteropeptidase. Enteropeptidase is involved in digestion in humans and animals .

HY-108883

Plasmin Fibrinolysins; Serum tryptase; TAL 05-00018	Biochemical Assay Reagents
Plasmin is an important protease present in blood that degrades many plasma proteins, including fibrin clots. Plasmin can also act as a potent regulator of the immune process and can directly interact with various cell types, including monocytes, macrophages, and dendritic cells .

HY-P2780

Cathepsin B	Biochemical Assay Reagents
Cathepsin B is a cysteine protease and is involved in multiple kinds of programmed cell death (including apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death) .

HY-P2895

Clostripain Clostridiopeptidase B	Biochemical Assay Reagents
Clostripain (Clostridiopeptidase B) is a proteolytic enzyme isolated from Clostridium histolyticum with esterase, amidase and protease activities and is a highly specific carboxypeptide targeting arginine key protease .

HY-108910

Chymotrypsin EC 3.4.21.1; Chymotrypsin A	Biochemical Assay Reagents
Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids .

HY-B2196

Gastric mucin 2 Publications Verification	Native Proteins
Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma.

HY-108848

Reteplase BM 06.022	Biochemical Assay Reagents
Reteplase (BM 06.022) is a recombinant plasminogen activator, consists of the kringle 2 and protease domains of human tissue-type plasminogen activator .

HY-P2729

Subtilisin EC 3.4.21.14	Biochemical Assay Reagents
Subtilisin, or rubinase, is a bacterial serine protease. Subtilisin can be used as a detergent additive with thermal stability, pH tolerance, and calcium dependent stability .

HY-137840

Hippuryl-L-phenylalanine	Biochemical Assay Reagents
Hippuryl-L-phenylalanine is a substrate of carboxypeptidase. Carboxypeptidase is a protease enzyme that related with obesity, epilepsy and neurodegeneration. Hippuryl-L-phenylalanine can be used for the determination of carboxypeptidase activity .

HY-W087937

Benzamidine hydrochloride hydrate 2 Publications Verification Benzenecarboximidamide hydrochloride hydrate	Biochemical Assay Reagents
Benzamidine (Benzenecarboximidamide) hydrochloride hydrate is a reversible competitive trypsin-like serine proteases inhibitor with K_is of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively .

HY-155909

m-PEG-NHS ester (MW 3400) mPEG-SC (MW 3400); mPEG-Succinimidyl ester (MW 3400)	Drug Delivery
m-PEG-NHS ester (MW 3400) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-155909A

m-PEG-NHS ester (MW 1000) mPEG-SC (MW 1000); mPEG-Succinimidyl ester (MW 1000)	Drug Delivery
m-PEG-NHS ester (MW 1000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-155909B

m-PEG-NHS ester (MW 550) mPEG-SC (MW 550); mPEG-Succinimidyl ester (MW 550)	Drug Delivery
m-PEG-NHS ester (MW 550) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-155909C

m-PEG-NHS ester (MW 350) mPEG-SC (MW 350); mPEG-Succinimidyl ester (MW 350)	Drug Delivery
m-PEG-NHS ester (MW 350) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-W591424

m-PEG-NHS ester (MW 2000) mPEG-SC (MW 2000); mPEG-Succinimidyl ester (MW 2000)	Drug Delivery
m-PEG-NHS ester (MW 2000) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.

HY-P3028

Ficain Ficin	Biochemical Assay Reagents
Ficain is an enzyme extract composed of several proteases that can be isolated from Ficus hispida L. and the latex of fig (Ficus carica). Ficain has different specificities in different proportions during fruit ripening. Ficain is widely used in protein hydrolysis, food, production of bioactive peptides and antibody fragments .

HY-138540

1-Dodecylimidazole 1 Publications Verification N-Dodecylimidazole	Cell Assay Reagents
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity .

HY-P2969

Complement factor I	Biochemical Assay Reagents
Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) .

HY-E70018

Picornain 3C

Biochemical Assay Reagents

Picornain 3C is a protease found in picornaviruses, which cleaves peptide bonds of non-terminal sequences. Picornain 3C is an intermediate between the serine peptidase chymotrypsin and the cysteine peptidase papain. Picornain 3C shows endopeptidase activity by selectively cleaving Gln-Gly bonds in the polyprotein of poliovirus and with substitution of Glu for Gln, and Ser or Thr for Gly in other picornaviruses .

HY-129047

Trypsin

4 Publications Verification

Biochemical Assay Reagents

Trypsin is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. Trypsin activates PAR2 and PAR4. Trypsin induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. Trypsin also promotes cell proliferation and differentiation. Trypsin can be used in the research of wound healing and neurogenic inflammation .

Cat. No.	Product Name	Target	Research Area

HY-P0283

Protease-Activated Receptor-2, amide 2 Publications Verification	Protease Activated Receptor (PAR)	Cancer
Protease-Activated Receptor-2, amide (SLIGKV-NH₂) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.

HY-P0297

Protease-Activated Receptor-4

Protease Activated Receptor (PAR) Others

Protease-Activated Receptor-4 is the agonist of proteinase-activated receptor-4 (PAR4).

HY-P1308

SLIGRL-NH2 protease-Activated Receptor-2 Activating Peptide	Protease Activated Receptor (PAR)	Inflammation/Immunology
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2) .

HY-P2518

Protease-Activated Receptor-1, PAR-1 Agonist	Protease Activated Receptor (PAR)	Inflammation/Immunology
Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor .

HY-P1308A

SLIGRL-NH2 TFA protease-Activated Receptor-2 Activating Peptide TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
SLIGRL-NH2 TFA (Protease-Activated Receptor-2 Activating Peptide TFA) is an agonist of Protease-Activated Receptor-2 (PAR-2) .

HY-P2518A

Protease-Activated Receptor-1, PAR-1 Agonist TFA	Protease Activated Receptor (PAR)	Cancer
Protease-Activated Receptor-1, PAR-1 Agonist TFA is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist TFA corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor .

HY-P2519

Protease-Activated Receptor-3 (PAR-3) (1-6), human	Protease Activated Receptor (PAR)	Inflammation/Immunology
Protease-Activated Receptor-3 (PAR-3) (1-6), human is a proteinase-activated receptor (PAR-3) agonist peptide .

HY-P2519A

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA	Protease Activated Receptor (PAR)	Inflammation/Immunology
Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a proteinase-activated receptor (PAR-3) agonist peptide .

HY-P4018

*HIV Protease* Substrate IV**	HIV Protease	Infection
HIV Protease Substrate IV is a substrate of HIV protease. HIV Protease Substrate IV can be used to measure the activity of HIV (human immunodeficiency virus) -1 protease .

HY-P2344

HIV Protease Substrate 1

HIV Protease Infection

HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .
HY-P2344A

HIV Protease Substrate 1 TFA

HIV Protease Infection

HIV Protease Substrate 1 TFA, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .

HY-P2502

*Hepatitis Virus C NS3 Protease* Inhibitor 2**	HCV Protease HCV	Infection
Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor of hepatitis C virus (HCV) NS3 protease, with a K_i of 41 nM .

HY-P3934

HIV Protease Substrate I

HIV Protease Infection

HIV Protease Substrate I is a chromogenic substrate of HIV-1 protease. HIV Protease Substrate I has the cleavage site of HIV protease .

HY-P3980

*HIV-1, HIV-2 Protease* Substrate**	HIV Protease	Infection
HIV-1, HIV-2 Protease Substrate is the substrate of HIV-1, HIV-2 protease. And there are 4 residues for conservative substitutions of the substrate binding residues of HIV-1 and *HIV-2 protease* .**

HY-P0018

Pepstatin 25+ Cited Publications Pepstatin A	HIV Protease Autophagy	Infection Inflammation/Immunology
Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease .

HY-P0018A

Pepstatin Trifluoroacetate 25+ Cited Publications Pepstatin A Trifluoroacetate	HIV Protease Autophagy	Infection Inflammation/Immunology
Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Trifluoroacetate also inhibits HIV protease .

HY-P0018C

Pepstatin acetate Pepstatin A acetate	HIV Protease Autophagy	Infection Inflammation/Immunology
Pepstatin (Pepstatin A) acetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin acetate also inhibits HIV protease .

HY-P0018B

Pepstatin Ammonium 25+ Cited Publications Pepstatin A Ammonium	HIV Protease Autophagy	Infection Inflammation/Immunology
Pepstatin (Pepstatin A) Ammonium is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Ammonium also inhibits HIV protease .

HY-P4773

*HSV-1 Protease* substrate**	HSV	Infection
HSV-1 Protease substrate is a peptide substrate for HSV-1 (Herpes Simplex Virus Type 1) protease, and the specificity constant (k_cat/K_m) at pH 7.5 for cleavage is 5.2 M ^-1 s ^-1 .

HY-151250

HIV-1 protease-IN-7

HIV Protease Infection

HIV-1 protease-IN-7 (compound 16) is an orally active HIV-1 protease inhibitor (IC₅₀=3.52 nM, EC₅₀=37 nM) .

HY-18234

Leupeptin	Ser/Thr Protease Virus Protease Cathepsin	Infection Inflammation/Immunology
Leupeptin is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin potently inhibits serine, cysteine and threonine proteases. Leupeptin inhibits M ^pro (the main *protease* of SARS-CoV-2) and also has anti-inflammatory activity .

HY-P3949

Fluorescent Substrate for Glu-Specific Proteases

Fluorescent Dye Others

Fluorescent Substrate for Glu-Specific Proteases is a V8 protease-Specific chromogenic substrate .

HY-P2942

Chymotrypsinogen	Ser/Thr Protease	Inflammation/Immunology
Chymotrypsinogen is an inactive precursor of Chymotrypsin (HY-108910). Chymotrypsin is a serine protease produced by the pancreas .

HY-P4243

Dansyl-Glu-Gly-Arg-Chloromethylketone	Ser/Thr Protease	Others
Dansyl-Glu-Gly-Arg-Chloromethylketone is a *protease* inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone inhibits activated porcine factor IX .

HY-P4466

Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2	HIV Protease	Infection
Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate of HIV-1 protease. Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 can be used to test HIV-1 protease activity .

HY-P5312

Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr	Peptides	Infection
Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr is a DEN NS2B-NS3 protease substrate. Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr is used for DEN NS2B-NS3 protease substrate peptide selective inhibitor development .

HY-P4517

Z-Tyr-Lys-Arg-pNA

Peptides Others

Z-Tyr-Lys-Arg-pNA is a chromogenic substrate. Z-Tyr-Lys-Arg-pNA can be used to detect the activity of subtilisin-type and yapsin-like proteases .
HY-18234B

Leupeptin Ac-LL

Peptides Metabolic Disease Inflammation/Immunology Cancer

Leupeptin Ac-LL is a protease inhibitor from actinomycetes. Leupeptin Ac-LL has antiplasmin activity .

HY-P3437

Dabcyl-KTSAVLQSGFRKM-Glu(Edans)-NH2	Virus Protease	Others
Dabcyl-KTSAVLQSGFRKM-Glu(Edans)-NH2 is a fluorogenic peptide, as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKM-Glu(Edans)-NH2 can be used for researching 2019-nCoV (COVID-19) infection.

HY-P2296

Abz-FRLKGGAPIKGV-EDDNP TFA	Fluorescent Dye	Others
Abz-FRLKGGAPIKGV-EDDNP TFA is a fluorogenic substrate used to measure the enzymatic activities of protease forms, such as papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV). Abz-FRLKGGAPIKGV-EDDNP TFA has the potential for study 2019-nCoV (COVID-19) infection .

HY-P4035

HCV NS4A Protein (18-40) (JT strain)	HCV	Infection
HCV NS4A Protein (18-40) (JT strain) is an HCV NS4A peptide, which comprised residues 18 to 40 of the NS4A protein and is known to increase the catalytic efficiency of NS3 protease .

HY-P2065

Ac-VEID-AMC

Fluorescent Dye Others

Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .
HY-P1436

Acetyl-pepstatin

HIV Infection

Acetyl-pepstatin is a potent classical inhibitor of aspartic proteases (PRs) with XMRV PR and HIV-1 PR K_i values of 712 nM and 13 nM .

HY-P2794

G0775	Bacterial	Infection Neurological Disease Inflammation/Immunology
G0775 is a molecule with potent, broad-spectrum activity against Gram-negative bacteria. G0775 is active against MDR bacteria. G0775 binds the LepB protease domain .

HY-P5510

Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 HCV NS3 protease substrate	Peptides	Others
Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. (This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM. Upon cleavage of this substrate, fluorescence can be monitored at Abs/Em = 355/500 nm.)

HY-P5975

Z-Leu-Leu-Leu-fluoromethyl ketone Z-LLL-FMK	Cathepsin SARS-CoV	Infection
Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) is a cysteine protease inhibitor. Z-Leu-Leu-Leu-fluoromethyl ketone inhibits SARS infection. Z-Leu-Leu-Leu-fluoromethyl ketone also protects mice against a T. crassiceps challenge .

HY-P3159

VPM peptide	Biochemical Assay Reagents	Others
VPM peptide is a dithiol protease-cleavable peptide cross-linker. VPM peptide can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel .

HY-122542

PPACK	PAI-1	Cardiovascular Disease
PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors .

HY-P3159A

VPM peptide TFA	Biochemical Assay Reagents	Others
VPM peptide TFA is a dithiol protease-cleavable peptide cross-linker. VPM peptide TFA can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel .

HY-W790014

Z-FG-NHO-BzOME

Cathepsin Infection

Z-FG-NHO-BzOME is a cysteine protease inhibitor that selectively inhibits cathepsin B, cathepsin L, cathepsin S, and papain .

HY-P2990

Enteropeptidase TMPRSS15	Ser/Thr Protease	Metabolic Disease
Enteropeptidase (TMPRSS15), a type II transmembrane serine protease and a physiological activator of trypsinogen. Enteropeptidase is associated with the brush border membrane (BBM) of the enterocytes in the upper small intestine. Trypsinogen is the primary substrate for Enteropeptidase. Enteropeptidase is involved in digestion in humans and animals .

HY-P0078

TRAP-6 4 Publications Verification PAR-1 agonist peptide; Thrombin Receptor Activator Peptide 6	Protease Activated Receptor (PAR)	Inflammation/Immunology
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4 .

HY-P2780

Cathepsin B	Peptides	Others
Cathepsin B is a cysteine protease and is involved in multiple kinds of programmed cell death (including apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death) .

HY-P2295

Dabcyl-KTSAVLQSGFRKME-Edans TFA 1 Publications Verification	SARS-CoV	Others
Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection .

HY-124237

N-Octanoyl-DL-homoserine lactone	Peptides	Others
N-Octanoyl-DL-homoserine lactone is a member of N-acyl homoserine lactones (AHLs) family, also one of the signal molecule of quorum-sensing (QS) signals. N-Octanoyl-DL-homoserine lactone can regulate the production of siderophores and present positive correlation in Aeromonas sobria strain AS7. N-Octanoyl-DL-homoserine lactone can also regulate the secretion of proteases and stimulate the production of total volatile basic nitrogen (TVB-N) .

HY-P3948

Fluorescent Substrate for Pro-Specific Proteases	Fluorescent Dye	Others
Fluorescent Substrate for Pro-Specific Proteases is a fluorescent substrate of pro-specific proteases. Fluorescent Substrate for Pro-Specific Proteases can be used to detect the hydrolysis rate and activity of target enzyme .

HY-P4443

Ac-GAK-AMC	Peptides	Others
Ac-GAK-AMC is a fluorescent substrate that can be used to measure protease activity. AMC (7-amino-4-methylcoumarin) is a fluorescent group. In the presence of protease, the protease will hydrolyze Ac-GAK-AMC into a fluorescent product .

HY-P4349

Pyr-Arg-Thr-Lys-Arg-AMC	Peptides	Others
Pyr-Arg-Thr-Lys-Arg-AMC is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors .

HY-P4349A

Pyr-Arg-Thr-Lys-Arg-AMC TFA	Peptides	Others
Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors .

HY-P2054

Mvt-101	HIV Protease	Infection
Mvt-101 is a hexapeptide-based inhibitor of HIV-1 protease. Mvt-101 is also reduced-peptide-bond inhibitor. Mvt-101 inhibits reproduction of the HIV virus by blocking protease action .

Cat. No.	Product Name

HY-K0012

Protease Inhibitor Cocktail, Bacteria (EDTA-Free, 100× in DMSO)
MCE Protease Inhibitor Cocktail, Bacteria (EDTA-Free, 100× in DMSO) protects proteins from degradation by endogenous proteases released during protein extraction and purification.

HY-K0013

Protease and Phosphatase Inhibitor Cocktail (EDTA-Free, 10× in ddH2O) 40+ Cited Publications
MCE Protease and Phosphatase Inhibitor Cocktail (EDTA-Free, 10× in ddH2O) protects protein from degradation by endogenous proteases released during protein extraction and purification.

HY-K0010

Protease Inhibitor Cocktail Maximum Cited Publications 978 Publications Verification
Protease inhibitor cocktail is used in cell lysates or tissue extracts to increase protein stability.

HY-K0011

Protease Inhibitor Cocktail, mini-Tablet

185+ Cited Publications

Protease inhibitor cocktail is used in cell lysates or tissue extracts to increase protein stability.

Cat. No.	Product Name	Target	Research Area

HY-P99593

Sofituzumab vedotin DMUC5754A	Antibody-Drug Conjugates (ADCs)	Cancer
Sofituzumab vedotin (DMUC5754A) is a MMAE-containing anti-MUC16 antibody-drug conjugate (ADC) with a protease-cleavable linker. Sofituzumab vedotin can be used for the research of cancer .

HY-P99283

Concizumab NN 7415; mAb 2021; Anti-TFPI Recombinant Antibody	Inhibitory Antibodies	Others
Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that binds to the Kunitz-type protease inhibitor (KPI) 2 structural domain of TFPI, thereby blocking the interaction of this structural domain with the FXa active site. Concizumab can be used in the study of haemophilia .

HY-P99050

Sutimlimab	Complement System	Cardiovascular Disease Inflammation/Immunology
Sutimlimab, a first-in-class complement protein component 1, s subcomponent (C1s) inhibitor, can be used for the research of cold agglutinin disease. C1s is a serine protease which cleaves C4 and C2 to form the C3 convertase .

HY-P99593A

Sofituzumab vedotin (solution) DMUC5754A (solution)	Antibody-Drug Conjugates (ADCs)	Cancer
Sofituzumab vedotin (DMUC5754A) (solution) is an antibody-drug conjugate (ADC) that contains the humanized IgG1 anti-MUC16 monoclonal antibody and a potent anti-mitotic agent, monomethyl auristatin E (MMAE), linked through a protease-cleavable linker .

Species:	Human (133) Virus (12) Mouse (37) Rat (6) Bovine (1) E.coli (5) Cynomolgus (1) Staphylococcus aureus (1) Pig (2)
Tag:	His (134) SUMO (2) Tag Free (39) Strep (2) Avi (4) Myc (2) GST (19) HA (1) Flag (6) B2M (1) Fc (7)
Source:	HEK293 (82) E. coli Cell-free (1) Sf9 insect cells (34) P. pastoris (9) E. coli (75)

Cat. No.	Compare	Product Name	Species	Source

HY-P70887

	Kallikrein-6 Protein, Human (HEK293, His) Kallikrein-6; Neurosin; protease M; SP59; Serine protease 18; Serine protease 9; Zyme; KLK6; PRSS18; PRSS9	Human	HEK293
	Kallikrein-6 is a serine protease that exhibits substrate preference and activity against different substrates. It degrades alpha-synuclein, plays a role in synucleinopathies, and may regulate axonal growth after spinal cord injury. Kallikrein-6 Protein, Human (HEK293, His) is the recombinant human-derived Kallikrein-6 protein, expressed by HEK 293 , with C-6*His labeled tag. The total length of Kallikrein-6 Protein, Human (HEK293, His) is 228 a.a., with molecular weight of 32 & 20 & 10 kDa, respectively.

HY-P71483

	Protease 7/OmpT Protein, E.coli (His) ompT; b0565; JW0554; protease 7; EC 3.4.23.49; Omptin; Outer membrane protein 3B; protease A; protease VII	E.coli	E. coli
	Protease 7/OmpT protein is a multifunctional enzyme that can cleave a variety of substrates, such as T7 RNA polymerase, ferric enterobactin receptor protein (FEP), and the antimicrobial peptide protamine. Its unique specificity for paired basic residues suggests a preference for specific amino acid configurations. Protease 7/OmpT Protein, E.coli (His) is the recombinant E. coli-derived Protease 7/OmpT protein, expressed by E. coli , with N-6*His labeled tag. The total length of Protease 7/OmpT Protein, E.coli (His) is 297 a.a., with molecular weight of ~37.5 kDa.

HY-P71290

	SENP8 Protein, Human (His) Sentrin-Specific protease 8; Deneddylase-1; NEDD8-Specific protease 1; protease Cysteine 2; Sentrin/SUMO-Specific protease SENP8; SENP8; DEN1; NEDP1; PRSC2	Human	E. coli
	SENP8 protein, a pivotal protease in the NEDD8 pathway, plays a dual role in catalyzing the processing of full-length NEDD8 into its mature form and facilitating the deconjugation of NEDD8 from specific target proteins, including cullins and p53. SENP8's dual functionality underscores its crucial role in regulating NEDD8 modification, impacting various cellular pathways and functions. SENP8 Protein, Human (His) is the recombinant human-derived SENP8 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SENP8 Protein, Human (His) is 212 a.a., with molecular weight of ~22.0 kDa.

HY-P71474

	Protease 7/OmpT Protein, E.coli (His-SUMO) ompT; Z1931; ECs1663; protease 7; EC 3.4.23.49; Omptin; Outer membrane protein 3B; protease A; protease VII	E.coli	E. coli
	Protease 7, or OmpT, displays unique proteolytic capabilities, cleaving diverse substrates like T7 RNA polymerase, ferric enterobactin receptor protein (FEP), and protamine. With specificity for paired basic residues, it selectively targets substrates with such motifs, highlighting its pivotal role in diverse biological processes and protein regulation. Protease 7/OmpT Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Protease 7/OmpT protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of Protease 7/OmpT Protein, E.coli (His-SUMO) is 297 a.a., with molecular weight of ~49.5 kDa.

HY-P71294

	Serpin E2 Protein, Mouse (HEK293, His) Glia-derived nexin; GDN; Peptidase inhibitor 7; PI-7; protease nexin 1; PN-1; protease nexin I; Serine protease-inhibitor 4; Serpin E2; Pi7; Pn1; Spi4	Mouse	HEK293
	Serpin E2, a serine protease inhibitor, inhibits thrombin, trypsin, and urokinase, with a notable role in promoting neurite extension by specifically inhibiting thrombin. Its ability to bind heparin underscores interactions with glycosaminoglycans. The multifaceted inhibitory functions of Serpin E2 highlight its significance in regulating serine protease activities and potential impact on cellular processes, particularly in neurodevelopment. Serpin E2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin E2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Serpin E2 Protein, Mouse (HEK293, His) is 378 a.a., with molecular weight of ~48 kDa.

HY-P71456

	PRSS3/Trypsin-3 Protein, Human (His) Brain trypsinogen; Mesotrypsin; Mesotrypsinogen; MTG; Pancreatic trypsinogen III; protease, serine, 3; PRSS3; PRSS4; Serine protease 3; Serine protease 4; T9; TRY3; TRY3_HUMAN; TRY4; Trypsin 3; Trypsin III; Trypsin IV; Trypsin-3; Trypsinogen 4; Trypsinogen 5; Trypsinogen IV	Human	E. coli
	PRSS3/Trypsin-3 is a digestive protease with specific substrate preference that cleaves proteins after Arg residues. This enzymatic activity is combined with its ability to exhibit proteolytic effects on Kunitz-type trypsin inhibitors. PRSS3/Trypsin-3 Protein, Human (His) is the recombinant human-derived PRSS3/Trypsin-3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PRSS3/Trypsin-3 Protein, Human (His) is 223 a.a., with molecular weight of ~28.2 kDa.

HY-P71294Y

	Serpin E2 Protein, Mouse (HEK293, His, solution) Glia-derived nexin; GDN; Peptidase inhibitor 7; PI-7; protease nexin 1; PN-1; protease nexin I; Serine protease-inhibitor 4; Serpin E2; Pi7; Pn1; Spi4	Mouse	HEK293
	Serpin E2, a serine protease inhibitor, inhibits thrombin, trypsin, and urokinase, with a notable role in promoting neurite extension by specifically inhibiting thrombin. Its ability to bind heparin underscores interactions with glycosaminoglycans. The multifaceted inhibitory functions of Serpin E2 highlight its significance in regulating serine protease activities and potential impact on cellular processes, particularly in neurodevelopment. Serpin E2 Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Serpin E2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Serpin E2 Protein, Mouse (HEK293, His, solution) is 378 a.a., with molecular weight of approximately 48 kDa.

HY-P72780

	Staphylokinase Protein, S. aureus Staphylokinase; Neutral proteinase; protease III; SakSTAR; sak	Staphylococcus aureus	E. coli
	Staphylokinase Protein efficiently converts plasminogen into active plasmin, a key enzyme in fibrinolysis. It forms a 1:1 complex with plasmin, activating additional plasminogen molecules and amplifying the fibrinolytic cascade. Staphylokinase Protein, S. aureus is the recombinant Staphylococcus aureus-derived Staphylokinase protein, expressed by E. coli , with tag free. The total length of Staphylokinase Protein, S. aureus is 136 a.a., with molecular weight of ~15.6 kDa.

HY-P70897

	Legumain Protein, Human (HEK293, His) Legumain; Asparaginyl Endopeptidase; protease Cysteine 1; LGMN; PRSC1	Human	HEK293
	Legumain proteins can slowly cleave aspartyl bonds, especially under acidic conditions. Legumain Protein, Human (HEK293, His) is the recombinant human-derived Legumain protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Legumain Protein, Human (HEK293, His) is 416 a.a., with molecular weight of 52-60 kDa.

HY-P71085

	Serpin E2 Protein, Human (HEK293, His) Glia-derived Nexin; GDN; Peptidase inhibitor 7; PI-7; protease nexin 1; PN-1; protease nexin I; Serpin E2; SERPINE2; PI7; PN1	Human	HEK293
	Serpin E2 is a serine protease inhibitor that inhibits thrombin, trypsin, and urokinase. Its unique role in promoting neurite extension involves specific inhibition of thrombin activity. Serpin E2 Protein, Human (HEK293, His) is the recombinant human-derived Serpin E2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin E2 Protein, Human (HEK293, His) is 378 a.a., with molecular weight of ~50.0 kDa.

HY-P75511

	Amyloid Precursor/Beta-APP40 Protein, Human (His-GST) Amyloid-beta precursor protein; APP; protease Nexin II; PreA4	Human	E. coli
	There is no specific Pubmed ID mentioned in the paragraph. Amyloid Precursor/Beta-APP40 Protein, Human (His-GST) is the recombinant human-derived Amyloid Precursor/Beta-APP40 protein, expressed by E. coli , with N-His, N-GST labeled tag. The total length of Amyloid Precursor/Beta-APP40 Protein, Human (His-GST) is 40 a.a., with molecular weight of ~33 kDa.

HY-P77438

	Legumain Protein, Pig (416a.a, HEK293, His) Legumain; Asparaginyl Endopeptidase; protease Cysteine 1; LGMN; PRSC1	Pig	HEK293
	Legumain proteins can slowly cleave aspartyl bonds, especially under acidic conditions. Legumain Protein, Pig (416a.a, HEK293, His) is the recombinant pig-derived Legumain protein, expressed by HEK293 , with N-His labeled tag. The total length of Legumain Protein, Pig (416a.a, HEK293, His) is 416 a.a., with molecular weight of ~52.5 kDa.

HY-P77439

	Legumain Protein, Pig (433a.a, HEK293, His) Legumain; Asparaginyl Endopeptidase; protease Cysteine 1; LGMN; PRSC1	Pig	HEK293
	Legumain proteins can slowly cleave aspartyl bonds, especially under acidic conditions. Legumain Protein, Pig (433a.a, HEK293, His) is the recombinant pig-derived Legumain protein, expressed by HEK293 , with C-His labeled tag. The total length of Legumain Protein, Pig (433a.a, HEK293, His) is 433 a.a., with molecular weight of ~53.7 kDa.

HY-P77199

	Serpin D1 Protein, Human (HEK293, His) Heparin cofactor 2; Heparin cofactor II; HC-II; protease inhibitor leuserpin-2	Human	HEK293
	Serpin D1 protein is a thrombin inhibitor activated by glycosaminoglycans such as heparin or dermatan sulfate. It replaces antithrombin III and becomes the main thrombin inhibitor in the presence of dermatan sulfate. In addition to thrombin inhibition, serpin D1 also has glycosaminoglycan-independent chymotrypsin inhibitory activity. Serpin D1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin D1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Serpin D1 Protein, Human (HEK293, His) is 480 a.a., with molecular weight of ~75-80 kDa.

HY-P70216A

	Legumain Protein, Mouse (HEK293, C-His) rMuLegumain/Asparaginyl Endopeptidase, His; Legumain; Lgmn; Asparaginyl endopeptidase; protease cysteine 1; Prsc1	Mouse	HEK293
	Legumain proteins can slowly cleave aspartyl bonds, especially under acidic conditions. Legumain Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Legumain protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Legumain Protein, Mouse (HEK293, C-His) is 418 a.a., with molecular weight of ~60.0 kDa.

HY-P70216B

	Legumain Protein, Mouse (HEK293, C-6His) rMuLegumain/Asparaginyl Endopeptidase, His; Legumain; Lgmn; Asparaginyl endopeptidase; protease cysteine 1; Prsc1	Mouse	HEK293
	Legumain proteins can slowly cleave aspartyl bonds, especially under acidic conditions. Legumain Protein, Mouse (HEK293, C-6His) is the recombinant mouse-derived Legumain protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Legumain Protein, Mouse (HEK293, C-6His) is 418 a.a., with molecular weight of ~54.8 kDa.

HY-P7694

	PRADC1 Protein, Human (HEK293, His) rHuPRADC1, His; protease-associated domain-containing protein 1; PRADC1; C2orf7	Human	HEK293
	PRADC1 Protein, Human (HEK293, His) is a recombinant human protease-associated domain-containing 1 (PRADC1) produced in HEK293 cells, with His tag. PRADC1 is a metabolic-responsive secretory protein that modulates physical activity and adiposity.

HY-P71293

	Serpin D1 Protein, Mouse (HEK293, His) Heparin cofactor 2; Heparin cofactor II; HC-II; protease inhibitor leuserpin-2; Serpin D1	Mouse	HEK293
	Serpin D1 is a thrombin inhibitor that is activated by glycosaminoglycans such as heparin or dermatan sulfate. In the presence of dermatan sulfate, HC-II surpasses antithrombin III (AT) as the primary thrombin inhibitor. Serpin D1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin D1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin D1 Protein, Mouse (HEK293, His) is 455 a.a., with molecular weight of 70-90 kDa.

HY-P73612

	Thrombin Receptor/PAR1 Protein, Human (HEK293, His) Cf2r; CF2RHTR; F2R; HTR; PAR1; protease-Activated Receptor 1	Human	HEK293
	The thrombin receptor/PAR1 protein is a high-affinity receptor for activated thrombin that is coupled to G proteins to stimulate phosphoinositide hydrolysis. This signaling mechanism suggests its involvement in platelet activation, which is critical for hemostasis and thrombosis. Thrombin Receptor/PAR1 Protein, Human (HEK293, His) is the recombinant human-derived Thrombin Receptor/PAR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Thrombin Receptor/PAR1 Protein, Human (HEK293, His) is 81 a.a., with molecular weight of ~10.2 kDa.

HY-P70143

	Kallikrein-10 Protein, Human (HEK293, His) rHuKallikrein-10/KLK10, His ; Kallikrein-10; Normal Epithelial Cell-Specific 1; protease Serine-Like 1; KLK10; NES1; PRSSL1	Human	HEK293
	Kallikrein-10 protein has a tumor suppressive effect, especially in breast and prostate cancer, by inhibiting NES1. This emphasizes its importance in mitigating tumorigenesis in these specific types of cancer. Kallikrein-10 Protein, Human (HEK293, His) is the recombinant human-derived Kallikrein-10 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Kallikrein-10 Protein, Human (HEK293, His) is 246 a.a., with molecular weight of ~34.0 kDa.

HY-P71638

	Elastase IIIB/CELA3B Protein, Mouse (Myc, His) Cela3b; Ela3; Ela3b; Chymotrypsin-like elastase family member 3B; EC 3.4.21.70; Elastase IIIB; Elastase-3B; protease E	Mouse	E. coli
	The elastase IIIB/CELA3B protein exhibits remarkable efficiency as a protease, showing a clear preference for alanine specificity while exhibiting limited elastolytic activity. This unique zymogram makes this protein a promising candidate for precise substrate cleavage, especially when processing alanine-rich substrates. Elastase IIIB/CELA3B Protein, Mouse (Myc, His) is the recombinant mouse-derived Elastase IIIB/CELA3B protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of Elastase IIIB/CELA3B Protein, Mouse (Myc, His) is 242 a.a., with molecular weight of ~31.1 kDa.

HY-P70133

	CELA3A Protein, Human (HEK293, His) rHuChymotrypsin-like elastase family member 3A/CELA3A, His; Chymotrypsin-Like Elastase Family Member 3A; Elastase IIIA; Elastase-3A; protease E; CELA3A; ELA3; ELA3A	Human	HEK293
	CELA3A Protein, an efficient alanine-specific protease, exhibits minimal elastolytic activity. CELA3A Protein, Human (HEK293, His) is the recombinant human-derived CELA3A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CELA3A Protein, Human (HEK293, His) is 255 a.a., with molecular weight of ~31.0 kDa.

HY-P70316

	Elafin/Trappin-2 Protein, Human (HEK293, His) rHuElafin, His; Elafin; Elastase-Specific Inhibitor; ESI; Peptidase Inhibitor 3; PI-3; protease inhibitor WAP3; Skin-Derived Antileukoproteinase; SKALP; WAP Four-Disulfide Core Domain Protein 14; PI3; WAP3; WFDC14	Human	HEK293
	Elafin/Trappin-2, a skin-specific inhibitor of neutrophil and pancreatic elastase, safeguards tissues against elastase-mediated proteolysis. Its inhibitory range extends to the alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor. Elafin/Trappin-2 also weakly inhibits Kv11.1/KCNH2/ERG1 and transient receptor potential cation channel subfamily V member 1 (TRPV1), as reported in studies. Elafin/Trappin-2 Protein, Human (HEK293, His) is the recombinant human-derived Elafin/Trappin-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Elafin/Trappin-2 Protein, Human (HEK293, His) is 95 a.a., with molecular weight of 13-15 kDa.

HY-P702648

	PKN1 Protein, Human (sf9, His, Flag) PKN1; protein kinase N1; PRKCL1, protein kinase C like 1; serine/threonine-protein kinase N1; DBK; MGC46204; PAK1; PKN; PRK1; protein kinase C-like 1; protein kinase PKN-alpha; protein kinase C-like PKN; serine-threonine kinase N; protease-activated kinase 1; protein kinase C-related kinase 1; protein-kinase C-related kinase 1; serine-threonine protein kinase N; serine/threonine protein kinase N; PAK-1; PRKCL1; PKN-ALPHA	Human	Sf9 insect cells

HY-P701468

	SENP3 Protein, Human SENP3; Sentrin-specific protease 3; SUMO-1-specific protease 3; Sentrin/SUMO-specific protease SENP3	Human	E. coli
	The SENP3 protein is a key protease in protein sumoylation and can efficiently release SUMO2 and SUMO3 from substrates but is less active on SUMO1 conjugates. Its regulatory effects span multiple cellular processes, including dissociation of SUMO2 from MEF2D, enhancing its transcriptional activation, and dissociation from CDCA8, affecting cellular dynamics. SENP3 Protein, Human is the recombinant human-derived SENP3 protein, expressed by E. coli , with tag free. The total length of SENP3 Protein, Human is 274 a.a., .

HY-P701469

	SENP3 Protein, Human (GST) SENP3; Sentrin-specific protease 3; SUMO-1-specific protease 3; Sentrin/SUMO-specific protease SENP3	Human	E. coli
	The SENP3 protein is a key protease in protein sumoylation and can efficiently release SUMO2 and SUMO3 from substrates but is less active on SUMO1 conjugates. Its regulatory effects span multiple cellular processes, including dissociation of SUMO2 from MEF2D, enhancing its transcriptional activation, and dissociation from CDCA8, affecting cellular dynamics. SENP3 Protein, Human (GST) is the recombinant human-derived SENP3 protein, expressed by E. coli , with N-GST labeled tag. The total length of SENP3 Protein, Human (GST) is 274 a.a., .

HY-P701473

	SENP6 Protein, Human (GST) SENP6; Sentrin-specific protease 6; SUMO-1-specific protease 1; Sentrin/SUMO-specific protease SENP6	Human	E. coli
	SENP6 protein is a key protease in protein sumoylation and is specifically responsible for dissociating SUMO1, SUMO2 and SUMO3 from target proteins. Its remarkable activity in processing SUMO2 and SUMO3 polymer chains highlights its selectivity among the SUMO series. SENP6 Protein, Human (GST) is the recombinant human-derived SENP6 protein, expressed by E. coli , with N-GST labeled tag. The total length of SENP6 Protein, Human (GST) is 485 a.a., .

HY-P701472

	SENP6 Protein, Human (sf9) SENP6; Sentrin-specific protease 6; SUMO-1-specific protease 1; Sentrin/SUMO-specific protease SENP6	Human	Sf9 insect cells
	SENP6 protein is a key protease in protein sumoylation and is specifically responsible for dissociating SUMO1, SUMO2 and SUMO3 from target proteins. Its remarkable activity in processing SUMO2 and SUMO3 polymer chains highlights its selectivity among the SUMO series. SENP6 Protein, Human (sf9) is the recombinant human-derived SENP6 protein, expressed by Sf9 insect cells , with tag free. The total length of SENP6 Protein, Human (sf9) is 485 a.a., .

HY-P77153

	Prostasin/PRSS8 Protein, Human (HEK293, His) Channel-activating protease 1; CAP1; Serine protease 8	Human	HEK293
	Prostasin/PRSS8, with trypsin-like cleavage specificity, crucially activates the epithelial sodium channel (ENaC) by cleaving its gamma subunits (SCNN1G). This protein forms a heterodimeric complex, consisting of light and heavy chains connected by a disulfide bond. Prostasin/PRSS8 Protein, Human (HEK293, His) is the recombinant human-derived Prostasin/PRSS8 protein, expressed by HEK293 , with C-His labeled tag. The total length of Prostasin/PRSS8 Protein, Human (HEK293, His) is 293 a.a., with molecular weight of ~40 kDa.

HY-P77154

	Prostasin/PRSS8 Protein, Mouse (sf9, His) Channel-activating protease 1; CAP1; Serine protease 8	Mouse	Sf9 insect cells
	Prostasin/PRSS8 Protein, featuring trypsin-like cleavage specificity, crucially activates the epithelial sodium channel (ENaC) by cleaving gamma subunits (SCNN1G) and modulating ion transport. Structurally, it forms a disulfide bond-linked heterodimer with light and heavy chains, highlighting its intricate role in cellular responses. Prostasin/PRSS8 Protein, Mouse (sf9, His) is the recombinant mouse-derived Prostasin/PRSS8 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Prostasin/PRSS8 Protein, Mouse (sf9, His) is 260 a.a., with molecular weight of ~35 kDa.

HY-P77155

	Prostasin/PRSS8 Protein, Rat (HEK293, His) Channel-activating protease 1; CAP1; Serine protease 8	Rat	HEK293
	Prostasin/PRSS8 Protein, featuring trypsin-like cleavage specificity, crucially activates the epithelial sodium channel (ENaC) by cleaving gamma subunits (SCNN1G) and modulating ion transport. Structurally, it forms a disulfide bond-linked heterodimer with light and heavy chains, highlighting its intricate role in cellular responses. Prostasin/PRSS8 Protein, Rat (HEK293, His) is the recombinant rat-derived Prostasin/PRSS8 protein, expressed by HEK293 , with C-His labeled tag. The total length of Prostasin/PRSS8 Protein, Rat (HEK293, His) is 293 a.a., with molecular weight of ~32.9 KDa.

HY-P702804

	SENP6 Protein, Human (sf9, GST) SENP6; Sentrin-specific protease 6; SUMO-1-specific protease 1; Sentrin/SUMO-specific protease SENP6	Human	Sf9 insect cells
	SENP6 protein is a key protease in protein sumoylation and is specifically responsible for dissociating SUMO1, SUMO2 and SUMO3 from target proteins. Its remarkable activity in processing SUMO2 and SUMO3 polymer chains highlights its selectivity among the SUMO series. SENP6 Protein, Human (sf9, GST) is the recombinant human-derived SENP6 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of SENP6 Protein, Human (sf9, GST) is 485 a.a., .

HY-P70108

	BSSP-4 Protein, Human (HEK293, His) rHuBrain-specific serine protease 4/BSSP-4, His; Brain-Specific Serine protease 4; BSSP-4; Serine protease 22; Serine protease 26; Tryptase Epsilon; PRSS22; BSSP4; PRSS26	Human	HEK293
	BSSP-4 Protein is notable for its specific preference in cleaving the synthetic substrate H-D-Leu-Thr-Arg-pNA over tosyl-Gly-Pro-Arg-pNA. This enzymatic selectivity indicates BSSP-4's potential modulation of specific peptide sequences, emphasizing its relevance in biological processes. BSSP-4 Protein, Human (HEK293, His) is the recombinant human-derived BSSP-4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of BSSP-4 Protein, Human (HEK293, His) is 285 a.a., with molecular weight of 33-35 kDa.

HY-P71289

	SENP7 Protein, Human Sentrin-Specific protease 7; SUMO-1-Specific protease 2; Sentrin/SUMO-Specific protease SENP7; SENP7; KIAA1707; SSP2; SUSP2	Human	E. coli
	SENP7, a versatile protease, positively regulates the cGAS-STING pathway by desumoylating CGAS, enhancing its DNA-binding and activation. Specific to SUMO2 and SUMO3, SENP7 proficiently deconjugates poly-SUMO2 and poly-SUMO3 chains, dynamically regulating protein sumoylation. While less efficient in processing full-length SUMO proteins, SENP7's role in modulating the cGAS-STING pathway highlights its importance in innate immune responses. SENP7 Protein, Human is the recombinant human-derived SENP7 protein, expressed by E. coli , with tag free. The total length of SENP7 Protein, Human is 170 a.a., with molecular weight of ~22.0 kDa.

HY-P701239AF

Animal-Free SUMO Protease Protein, Saccharomyces cerevisiae (His)

SUMO protease
Others E. coli

HY-P701470

	SENP5 Protein, Human SENP5; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5	Human	E. coli
	The SENP5 protein is critical in the SUMO pathway and promotes the regulation of SUMOylation through two key functions. First, it processes full-length SUMO3 into its mature form, facilitating the maturation of this ubiquitin-like modifier. SENP5 Protein, Human is the recombinant human-derived SENP5 protein, expressed by E. coli , with tag free. The total length of SENP5 Protein, Human is 220 a.a., .

HY-P701471

	SENP5 Protein, Human (GST) SENP5; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5	Human	E. coli
	The SENP5 protein is critical in the SUMO pathway and promotes the regulation of SUMOylation through two key functions. First, it processes full-length SUMO3 into its mature form, facilitating the maturation of this ubiquitin-like modifier. SENP5 Protein, Human (GST) is the recombinant human-derived SENP5 protein, expressed by E. coli , with N-GST labeled tag. The total length of SENP5 Protein, Human (GST) is 220 a.a., .

HY-P7381

	Kallikrein-11 Protein, Human (Sf9) rHuKallikrein-11; TLSP; hK11; Hippostasin; Trypsin-like protease; Serine protease 20	Human	Sf9 insect cells
	Kallikrein 11 Protein, Human (Sf9) is a possible multifunctional protease and efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin.

HY-P73263

	Kallikrein-11 Protein, Human (HEK293, His) Kallikrein-11; TLSP; hK11; Hippostasin; Trypsin-like protease; Serine protease 20	Human	HEK293
	Kallikrein-11 protein is suggested to be a multifunctional protease, efficiently cleaving the substrate 'bz-Phe-Arg-4-methylcoumaryl-7-amide' and showing weak cleavage activity toward other kallikrein and trypsin substrates. It predominantly cleaves synthetic peptides after arginine residues rather than lysine residues. Kallikrein-11 Protein, Human (HEK293, His) is the recombinant human-derived Kallikrein-11 protein, expressed by HEK293 , with C-His labeled tag. The total length of Kallikrein-11 Protein, Human (HEK293, His) is 232 a.a., with molecular weight of ~40 kDa.

HY-P73847

	Kallikrein-11 Protein, Mouse (HEK293, His) Kallikrein-11; TLSP; hK11; Hippostasin; Trypsin-like protease; Serine protease 20	Mouse	HEK293
	Kallikrein-11 protein, a potential multifunctional protease, demonstrates efficient cleavage of the substrate 'bz-Phe-Arg-4-methylcoumaryl-7-amide,' specific to kallikrein. It also displays weaker cleavage activity toward other substrates linked to kallikrein and trypsin. This multifunctional characteristic indicates versatility in substrate recognition and cleavage, suggesting a potential role in diverse proteolytic processes. Kallikrein-11 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kallikrein-11 protein, expressed by HEK293 , with C-His labeled tag. The total length of Kallikrein-11 Protein, Mouse (HEK293, His) is 232 a.a., with molecular weight of 35-43 kDa.

HY-P77078

	*Mast Cell Protease-1/MCPT-1 Protein, Mouse (HEK293, His)* Mast cell protease 1; mMCP-1; Mcpt1	Mouse	HEK293
	Mast Cell Protease-1 (MCPT-1) displays chymotrypsin-like enzymatic activity. Mast Cell Protease-1/MCPT-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Mast Cell Protease-1/MCPT-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Mast Cell Protease-1/MCPT-1 Protein, Mouse (HEK293, His) is 228 a.a., with molecular weight of 32-34 kDa.

HY-P71604

	*Transmembrane protease* serine 4 Protein, Mouse (His-SUMO)** Tmprss4; Cap2; Transmembrane protease serine 4; EC 3.4.21.-; Channel-activating protease 2; mCAP2	Mouse	E. coli
	The transmembrane protease serine 4 (TMPRSS4) protein is a plasma membrane-anchored serine protease that is critical for activating molecular pathways. Its proteolytic activity directly processes pro-uPA/PLAU into its active form. Transmembrane protease serine 4 Protein, Mouse (His-SUMO) is the recombinant mouse-derived Transmembrane protease serine 4 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of Transmembrane protease serine 4 Protein, Mouse (His-SUMO) is 384 a.a., with molecular weight of ~57.8 kDa.

HY-P7341AF

Animal-Free Enterokinase Protein, Bovine (His)

Enteropeptidase; Enterokinase; Serine protease 7; Transmembrane protease serine 15; Enteropeptidase; ENTK; PRSS7
Bovine P. pastoris

HY-P72043

	TMPRSS2 Protein, Human (P.pastoris, His) 1 Publications Verification Serine protease 10; PRSS10	Human	P. pastoris
	The TMPRSS2 protein is a plasma membrane-anchored serine protease that plays critical roles in prostate physiology, cancer metastasis, pain modulation, and viral infection. Its lytic activity affects proteolytic cascades involved in prostate function, and androgen-induced activation contributes to cancer progression. TMPRSS2 Protein, Human (P.pastoris, His) is the recombinant human-derived TMPRSS2 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of TMPRSS2 Protein, Human (P.pastoris, His) is 387 a.a., with molecular weight of ~45 kDa.

HY-P76590

SARS-CoV-2 3CLpro/3C-like protease Protein (His-Avi)

3CL protease; 3CL Proteinase; 3C-like main protease; 3CL-Mpro; COVID-19; M Proteinase; Main protease; Mpro
Virus E. coli
HY-P76589

SARS-CoV-2 3CLpro/3C-like protease Protein (sf9, His)

3CL protease; 3CL Proteinase; 3C-like main protease; 3CL-Mpro; COVID-19; M Proteinase; Main protease; Mpro
Virus Sf9 insect cells

HY-P72044

	TMPRSS2 Protein, Human (R255Q, HEK293, His) Serine protease 10	Human	HEK293
	The TMPRSS2 protein is a plasma membrane-anchored serine protease that plays critical roles in prostate physiology, cancer metastasis, pain modulation, and viral infection. Its lytic activity affects proteolytic cascades involved in prostate function, and androgen-induced activation contributes to cancer progression. TMPRSS2 Protein, Human (R255Q, HEK293, His) is the recombinant human-derived TMPRSS2 protein, expressed by HEK293 , with N-10*His labeled tag and R255Q, , , , mutation. The total length of TMPRSS2 Protein, Human (R255Q, HEK293, His) is 387 a.a., with molecular weight of ~46.71 kDa.

HY-P74772

	*Lon Protease* Protein, E. coli (His)** ATP-dependent protease La; lon; capR; deg; lopA; muc	E.coli	E. coli
	Lon Protease, an ATP-dependent serine protease, selectively degrades mutant proteins, short-lived regulators, and specific antitoxins, vital for cellular homeostasis. Crucial for survival during DNA damage and stress-induced changes, it processively degrades polypeptides into 5-10 amino acid fragments. Lon Protease also exhibits site-specific, double-stranded DNA binding. Its substrates include RcsA, SulA, SoxS, UmuD, and type II antitoxins like CcdA, HipB, and MazE. Notably, overproduced Lon Protease selectively hinders translation through pathways, including the YoeB-YefM toxin-antitoxin system. Lon Protease Protein, E. coli (His) is the recombinant E. coli-derived Lon Protease protein, expressed by E. coli, with C-His labeled tag. The total length of Lon Protease Protein, E. coli (His) is 784 a.a., with molecular weight of ~88 kDa.

HY-P79457

	USP2 Catalytic Domain Protein, Human (His) Ubiquitin Specific Peptidase 2; UBP41; Ubiquitin-Specific-Processing protease 2; Ubiquitin Carboxyl-Terminal Hydrolase 2; 41 KDa Ubiquitin-Specific protease; Deubiquitinating Enzyme 2; Ubiquitin-specific protease 2	Human	E. coli
	USP2 catalytic domain proteins act as hydrolases and target polyubiquitinated proteins such as MDM2, MDM4, and CCND1. Both isoform 1 and isoform 4 exhibit ubiquitin-specific peptidase and isopeptidase activities. USP2 Catalytic Domain Protein, Human (His) is the recombinant human-derived USP2 Catalytic Domain protein, expressed by E. coli , with N-6*His labeled tag. The total length of USP2 Catalytic Domain Protein, Human (His) is 347 a.a., .

HY-P70869

	TMPRSS11B Protein, Human (HEK293, His) Transmembrane protease Serine 11B; Airway Trypsin-Like protease 5; TMPRSS11B; HATL5	Human	HEK293
	TMPRSS11B, a serine protease, is susceptible to inhibition by aprotinin, leupeptin, benzamidine, SERPINA1, SPINT1, and SPINT2, highlighting its susceptibility to various regulatory mechanisms. TMPRSS11B Protein, Human (HEK293, His) is the recombinant human-derived TMPRSS11B protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TMPRSS11B Protein, Human (HEK293, His) is 378 a.a., with molecular weight of ~61.0 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P83186

PRSS2 Antibody (YA2931)

Pancreatic anionic trypsinogen; protease; serine; 2; PRSS2; TRYP8
WB Human, Mouse, Rat

HY-P81251

CASP4 Antibody Caspase-4 subunit 2; Caspase-4 subunit p10; Caspase-11; CASP-11; protease ICH-3; Apoptosis related cysteine peptidase; Apoptotic cysteine protease Mih1/TX; CASP 4; CASP 4; CASP-4; CASP4; CASP4_HUMAN; CASP4_MOUSE; Caspase 4 apoptosis related cysteine peptidase; Caspase-4 subunit 2; Caspase4; ICE(rel) II; ICE(rel)-II; ICE(rel)II; ICEREL II; ICERELII; ICH 2; ICH 2 protease; ICH2; Mih1/TX; Mih1/TX; protease ICH-2; protease TX; TX; TX protease; EC:3.4.22.64.	WB, ELISA	Rat (predicted: Mouse)

HY-P81385

Amyloid Precursor Protein Antibody (YA1130) APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; protease nexin-II; PN-II	IHC-P	Human

HY-P82823

Phospho-Amyloid Precursor Protein (Thr743) Antibody (YA2568) APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; protease nexin-II; PN-II	WB, ICC/IF, IP	Human, Rat

HY-P83027

Cleaved-Caspase 2 Antibody (YA2772) Caspase-2; Caspase 2; Caspase2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; protease ICH-1; CASP2; ICH1; NEDD2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

HY-P80624

Cleaved-Caspase 8 Antibody CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
Cleaved-Caspase 8 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 55 kDa, targeting to Cleaved-Caspase 8. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P81252

Caspase-5 p20 Antibody Caspase-5 subunit p20; Apoptosis related cysteine protease; CASP 5; CASP5; Caspase-5; Caspase5; Caspase 5 apoptosis related cysteine peptidase; caspase 5 apoptosis related cysteine protease; ICE; ICE(rel) III; ICE(rel)III; ICEREL III; ICERELIII; ICH 3; ICH 3 protease; ICH3; ICH3 protease; MGC141966; TY; TY protease.	WB, IHC-P, IHC-F, IF, ELISA	Human, Mouse (predicted: Rat, Rabbit, Pig, Cow, Dog, Horse)

HY-P82621

Caspase 10 Antibody (YA2366) CASP10; MCH4; Caspase-10; CASP-10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4	WB, IHC-P, IP	Human

HY-P82169

BACE1 Antibody (YA1914) BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2	WB, IP	Human, Mouse, Rat

HY-P82279

SENP2 Antibody (YA2024)

Axam2; Senp2; Sentrin specific protease 2; SMT3 specific isopeptidase 2; Smt3ip2
WB, IHC-P, ICC/IF Human

HY-P81161

CEBP-alpha Antibody Apoptotic cysteine protease; Apoptotic protease Mch 5; C/EBP alpha; CAP4; Caspase 8 precursor; CCAAT Enhancer Binding Protein alpha; CEBP; CEBP A; CEBP alpha; CEBPA; FADD homologous ICE/CED 3 like protease; FADD like ICE; FLICE; ICE like apoptotic protease 5; ICE8; MACH; MCH5; MORT1 associated CED 3 homolog; CEBP α, CEBP-α.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; ICC; IF	Human, Rat(predicted: Mouse, Dog, Pig, Cow, Rabbit, Sheep, Goat)
CEBP-alpha Antibody is an unconjugated, approximately 39 kDa, rabbit-derived, anti-CEBP-alpha polyclonal antibody. CEBP-alpha Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, rat, and predicted: mouse, dog, pig, cow, rabbit, sheep, goat background without labeling.

HY-P81788

Mast Cell Tryptase Antibody (YA1533)

TPS1; TPS2; TPSAB1; TPSB1; MCP 7; Mast cell protease 7; Tryptase alpha 1
WB, IHC-P, IP Human, Mouse, Rat
HY-P82611

Transmembrane Protease Serine 2 Antibody (YA2356)

Epitheliasin; PRSS10; TMPRSS2
WB, IHC-P, ICC/IF, FC Human, Mouse, Rat
HY-P83069

CLPX Antibody (YA2814)

ATP-dependent Clp protease ATP-binding subunit clpX-like; mitochondrial; CLPX
WB, ICC/IF Human, Mouse, Rat, Hamster

HY-P81736

APAF1 Antibody (YA1481) APAF; APAF-1; APAF1; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; Apoptotic protease-activating factor 1; CED4; DKFZp781B1145; KIAA0413	WB, IHC-P, ICC/IF	Human, Mouse

HY-P81812

Caspase 6 Antibody (YA1557)

CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
WB Human, Rat

HY-P80926

USP7 Antibody (YA657) Deubiquitinating enzyme 7; HAUSP; herpes virus associated; Herpes virus associated ubiquitin specific protease; Herpesvirus-associated ubiquitin-specific protease; TEF 1; tef-1; TEF1; Ubiquitin carboxyl terminal hydrolase 7; Ubiquitin carboxyl-terminal hy	WB	Human
USP7 Antibody (YA657) is a non-conjugated and Mouse origined monoclonal antibody about 128 kDa, targeting to USP7 (3E4). It can be used for WB assays with tag free, in the background of Human.

HY-P81697

FAP Antibody (YA1442)

FAP; Seprase; 170 kDa melanoma membrane-bound gelatinase; Fibroblast activation protein alpha; Integral membrane serine protease
FC, ELISA Human

HY-P81345

Fibroblast activation protein, alpha Antibody (YA1090) FAP; Seprase; 170 kDa melanoma membrane-bound gelatinase; Fibroblast activation protein alpha; Integral membrane serine protease	IHC-P	Human

HY-P81377

alpha 1-Antitrypsin Antibody (YA1122)

SERPINA1; AAT; PI; Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1
IHC-P Human

HY-P81215

Neutrophil Elastase Antibody Bone Marrow Serine protease; ELA 2; ELA2; ELANE; Elastase 2; Elastase-2; Elastase 2 neutrophil; Elastase neutrophil expressed; Elastase-2; ELNE_HUMAN; GE antibody Granulocyte derived elastase; HLE; HNE; Human leukocyte elastase; Leukocyte elastase; Leukocyte Elastase Precursor; Medullasin; NE; Neutrophil elastase; Neutrophill elastase; PMN E; PMN Elastase; Polymorphonuclear elastase; SCN1; Serine protease; SERP1.	WB; ELISA; Flow-Cyt;	Human, Mouse, Rat(predicted: Dog)
Neutrophil Elastase Antibody is an unconjugated, approximately 26 kDa, rabbit-derived, anti-Neutrophil Elastase polyclonal antibody. Neutrophil Elastase Antibody can be used for: WB, ELISA, Flow-Cyt, expriments in human, mouse, rat, and predicted: dog background without labeling.

HY-P80623

Cleaved-Caspase 3 p12 Antibody CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1	WB, ICC/IF	Human, Mouse, Rat
Cleaved-Caspase 3 p12 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 32 kDa, targeting to Cleaved-Caspase 3 p12. It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P82235

SERPING1 Antibody (YA1980)

SERPING1; C1IN; C1NH; Plasma protease C1 inhibitor; C1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1
WB, IP Human, Mouse, Rat

HY-P81117

MMP7 Antibody Matrilysin; Matrilysin uterine; Matrin; Matrix Metalloproteinase 7; MMP-7; MMP 7; MMP7; MPSL1; PUMP 1; Pump 1 protease; PUMP1; Uterine Matrilysin; Uterine metalloproteinase; MMP7_HUMAN.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse(predicted: Rat)
MMP7 Antibody is an unconjugated, approximately 30 kDa, rabbit-derived, anti-MMP7 polyclonal antibody. MMP7 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, and predicted: rat background without labeling.

HY-P81738

OTUB1 Antibody (YA1483) OTUB1; OTB1; OTU1; HSPC263; Ubiquitin thioesterase OTUB1; Deubiquitinating enzyme OTUB1; OTU domain-containing ubiquitin aldehyde-binding protein 1; Otubain-1; hOTU1; Ubiquitin-specific-processing protease OTUB1	WB, IP	Human, Mouse, Rat

HY-P81243

F2 Antibody Des-gamma-carboxy (abnormal)prothrombin; Des-Gamma-carboxy-prothrombin; coagulation factor II (thrombin); Coagulation factor II; DCP; Factor II; Prepro coagulation factor II; Prothrombin; prothrombin B-chain; PT; RPRGL2; serine protease; THPH1; THRB; THRB_HUMAN; Thrombin heavy chain.	WB=1:500-2000; ELISA=1:5000-10000; IHC-P=1:100-500; IHC-F=1:100-500; Flow-Cyt=1ug/test; IF=1:100-500	Human, Mouse, Rat

HY-P80557

ATG4A Antibody ATG4A; APG4A; AUTL2; Cysteine protease ATG4A; AUT-like 2 cysteine endopeptidase; Autophagin-2; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; hAPG4A	WB, IHC-P, IP	Human
ATG4A Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 45 kDa, targeting to ATG4A. It can be used for WB,IHC-P,IP assays with tag free, in the background of Human .

HY-P80558

ATG4C Antibody ATG4C; APG4C; AUTL1; AUTL3; Cysteine protease ATG4C; AUT-like 3 cysteine endopeptidase; Autophagin-3; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C	WB, IHC-P	Human
ATG4C Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 52 kDa, targeting to ATG4C. It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P82723

ATG4B Antibody (YA2468) ATG4B; APG4B; AUTL1; KIAA0943; Cysteine protease ATG4B; AUT-like 1 cysteine endopeptidase; Autophagin-1; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B; hAPG4B	WB, FC	Human, Mouse, Rat

HY-P80715

HtrA2 Antibody (YA726) High temperature requirement protein A2; HTRA 2; HtrA like serine protease; HtrA serine peptidase 2; HtrA; E. coli; homolog of; 2; HtrA2; HTRA2_HUMAN; mitochondrial; Omi stress regulated endoprotease; Omi stress-regulated endoprotease; PARK 13; PARK13; Pr	WB, IP	Human
HtrA2 Antibody (YA726) is a non-conjugated and Mouse origined monoclonal antibody about 49 kDa, targeting to HtrA2 (8G11). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P81095

Caspase-12 Antibody UNQ9415; Apoptosis related cysteine protease; CASP 12; casp12; CASP12P1; Caspase 12 pseudogene 1; CASP-12; casp12; caspase 12 (gene/pseudogene); Caspase12; CASPC_HUMAN; OTTHUMP00000207026; OTTHUMP00000207028; OTTHUMP00000207031; OTTHUMP00000207032; OTTHUMP00000219058; UNQ9415.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse, Rat,
Caspase-12 Antibody is an unconjugated, approximately 46 kDa, rabbit-derived, anti-Caspase-12 polyclonal antibody. Caspase-12 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, background without labeling.

HY-P81232

Caspase-1 p20 Antibody caspase-1 isoform alpha p20 subunit; CASP1; ICE; IL1BC; Caspase-1 subunit p20; CASP 1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1_HUMAN; CASP1_MOUSE.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; ICC; IF	Human, Mouse, Rat,
Caspase-1 p20 Antibody is an unconjugated, approximately 20/46 kDa, rabbit-derived, anti-Caspase-1 p20 polyclonal antibody. Caspase-1 p20 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, background without labeling.

Cat. No.	Product Name		Classification

HY-W027544S1

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 5-(Dimethyl-d6-amino)-N-(prop-2-ynyl)naphthalene-1-sulfonamide		Alkynes
(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d₆ is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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