quinine

By Targets:	Bacterial (2) Cytochrome P450 (1) Dengue virus (5) Flavivirus (5) Parasite (9) Potassium Channel (7)
By Research Areas:	Cardiovascular Disease (1) Infection (9)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0143

*Quinine* 2 Publications Verification	Flavivirus Dengue virus Parasite Potassium Channel	Infection
Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-B0433A

Quinine hydrochloride dihydrate 2 Publications Verification	Flavivirus Dengue virus Parasite Potassium Channel	Infection
Quinine hydrochloride dihydrate (Qualaquin) is an orally active and can be used in anti-malarial studies. Quinine hydrochloride dihydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-W010668

Quinine sulfate hydrate 2 Publications Verification	Flavivirus Dengue virus Parasite Potassium Channel	Others
Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-D0143A

Quinine dihydrochloride	Flavivirus Dengue virus Parasite Potassium Channel	Infection
Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-B0433B

Quinine hemisulfate	Flavivirus Dengue virus Parasite Potassium Channel	Infection
Quinine hemisulfate is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine hemisulfate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-B1401

Euquinine quinine ethyl carbonate	Others	Infection
Euquinine is an odorless salt that can be used as a substitute for quinine. Euquinine has anti-Plasmodium falciparum activity. Euquinine can be used for the study of multidrug resistance and bioavailability of Plasmodium falciparum .

HY-D0143B

Quinine hemisulfate hydrate	Parasite Potassium Channel	Infection
Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV, with an IC₅₀ of 169 μM .

HY-B1751B

Quinine sulfate
Quinidine sulfate is an antiarrhythmic agent. Quinidine sulfate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine sulfate is also a K ⁺ channel blocker with an IC₅₀ of 19.9 μM. Quinidine sulfate can be used for malaria research .

HY-B1751C

Quinine hydrobromide	Parasite Cytochrome P450 Potassium Channel	Infection
Quinidine hydrobromide is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine hydrobromide is also a K ⁺ channel blocker with an IC₅₀ of 19.9 μM. Quinidine hydrobromide can be used for malaria research .

HY-W048510

Epiquinidine

Others Others

Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM .
HY-N7354

Quininic acid

Others Cardiovascular Disease

Quininic acid, purified from Eucalyptus globulus, cinchona bark, and other plant products, is the most abundant organic acid .

Epiquinidine	Others	Others
Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM .

Quininic acid	Others	Cardiovascular Disease
Quininic acid, purified from Eucalyptus globulus, cinchona bark, and other plant products, is the most abundant organic acid .

HY-136429

Ethylhydrocupreine Optochin	Bacterial Parasite	Infection
Ethylhydrocupreine (Optochin) is a quinine derivate with antimicrobial activity against *S. pneumoniae. Ethylhydrocupreine also possesses antimalarial activity against Plasmodium falciparum, with an IC₅₀* of 25.75 nM. Ethylhydrocupreine is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist .

HY-136429A

Ethylhydrocupreine hydrochloride Optochin hydrochloride	Bacterial Parasite	Infection
Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a quinine derivate with antimicrobial activity against *S. pneumoniae. Ethylhydrocupreine hydrochloride also possesses antimalarial activity against Plasmodium falciparum, with an IC₅₀* of 25.75 nM. Ethylhydrocupreine hydrochloride is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist .

Cat. No.	Product Name

HY-L071

Alkaloids Library	530 compounds
Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds. MCE designs a unique collection of 530 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Alkaloids Library

530 compounds

Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds.

MCE designs a unique collection of 530 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D0143

*Quinine* 2 Publications Verification	Infection Cinchona succirubra Pav. ex Klotzsch Alkaloids Structural Classification Classification of Application Fields Source classification Rubiaceae Quinoline Alkaloids Plants Disease Research Fields	Flavivirus Dengue virus Parasite Potassium Channel
Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-B0433A

Quinine hydrochloride dihydrate 2 Publications Verification	Infection Alkaloids Structural Classification Classification of Application Fields Source classification Rubiaceae Quinoline Alkaloids Plants Disease Research Fields Cinchona ledgeriana (Howard) Moens et Trim	Flavivirus Dengue virus Parasite Potassium Channel
Quinine hydrochloride dihydrate (Qualaquin) is an orally active and can be used in anti-malarial studies. Quinine hydrochloride dihydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-W010668

Quinine sulfate hydrate 2 Publications Verification	Source classification Plants	Flavivirus Dengue virus Parasite Potassium Channel
Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-D0143A

Quinine dihydrochloride	Cinchona succirubra Pav. ex Klotzsch Natural Products Source classification Rubiaceae Plants	Flavivirus Dengue virus Parasite Potassium Channel
Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-B0433B

Quinine hemisulfate	Cinchona succirubra Pav. ex Klotzsch Source classification Rubiaceae Quinoline Alkaloids Plants	Flavivirus Dengue virus Parasite Potassium Channel
Quinine hemisulfate is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine hemisulfate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM .

HY-D0143B

Quinine hemisulfate hydrate	Infection Alkaloids Classification of Application Fields Source classification Rubiaceae Quinoline Alkaloids Plants Disease Research Fields Cinchona ledgeriana (Howard) Moens et Trim	Parasite Potassium Channel
Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV, with an IC₅₀ of 169 μM .

HY-W048510

Epiquinidine	Alkaloids Structural Classification other families Classification of Application Fields Source classification Other Diseases Quinoline Alkaloids Plants Disease Research Fields	Others
Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM .

HY-N7354

Quininic acid	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Rubiaceae Plants Disease Research Fields Cinchona ledgeriana (Howard) Moens et Trim	Others
Quininic acid, purified from Eucalyptus globulus, cinchona bark, and other plant products, is the most abundant organic acid .

Cat. No.	Compare	Product Name	Species	Source

HY-P702259

	CYP3A4 Protein, Human (Cell-Free, His) sulfoxide-forming; ; Albendazole sulfoxidase; CYPIIIA3; CYPIIIA4; Cholesterol 25-hydroxylase; Cytochrome P450 3A3; Cytochrome P450 HLp; Cytochrome P450 NF-25; Cytochrome P450-PCN1; Nifedipine oxidase; quinine 3-monooxygenase	Human	E. coli Cell-free
	CYP3A4 Protein, a cytochrome P450 monooxygenase, catalyzes diverse substrate metabolism, including sterols, hormones, and fatty acids. Mechanistically, it employs molecular oxygen for hydroxylation, impacting androgen metabolism, cholesterol, and retinoid pathways. Notably, it contributes to drug metabolism and regulates vitamin D catabolism, essential for calcium homeostasis. CYP3A4 Protein, Human (Cell-Free, His) is the recombinant human-derived CYP3A4 protein, expressed by E. coli Cell-free, with N-10*His labeled tag. The total length of CYP3A4 Protein, Human (Cell-Free, His) is 502 a.a., with molecular weight of 63.3 kDa.


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Screening Libraries

Natural
Products

Recombinant Proteins