Search Result

Results for "

reproductive

" in MCE Product Catalog:

By Targets:	Androgen Receptor (1) Antibiotic (2) Antifolate (2) Apoptosis (2) Bacterial (4) Caspase (1) Dopamine Receptor (2) Endogenous Metabolite (8) Estrogen Receptor/ERR (2) Ferroptosis (1) Fluorescent Dye (1) Fungal (1) Kisspeptin Receptor (2) Lipoxygenase (1) nAChR (1) Neurokinin Receptor (1) Parasite (3) Progesterone Receptor (1) Reactive Oxygen Species (2) RET (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (2) Endocrinology (13) Infection (8) Inflammation/Immunology (7) Metabolic Disease (2) Neurological Disease (6)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas

HY-B0823

Acetamiprid	nAChR	Neurological Disease
Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders.

HY-127170

3-Hydroxycoumarin	Lipoxygenase	Others
3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage.

HY-B1866

Linuron	Androgen Receptor	Endocrinology
Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a K_i of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor.

HY-147089

PRRSV/CD163-IN-1	Bacterial Endogenous Metabolite	Infection Inflammation/Immunology
PRRSV/CD163-IN-1 is a PRRSV/CD163 inhibitor. PRRSV/CD163-IN-1 can inhibit the interaction between the PRRSV glycoprotein (GP2a or GP4) and the CD163-SRCR5 domain. PRRSV/CD163-IN-1 can be used for the research of porcine reproductive and respiratory syndrome (PRRS) .

HY-134400

Follicle-stimulating hormone	Others	Endocrinology
Follicle-stimulating hormone is a heterodimer glycoprotein expressed by gonadotropin in the anterior pituitary gland. Follicle-stimulating hormone affects the fertility and reproductive efficiency of animals.

HY-B0847

Propiconazole	Fungal Reactive Oxygen Species	Infection
Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals.

HY-148163

Polystyrene	Others	Others
Polystyrene forms Polystyrene microplastics (PS-MPs), a hazardous material with potential toxicity. Polystyrene microplastics is harm to zebrafish heart and induces male reproductive toxicity in mice.

HY-N6710

α-Zearalenol	Estrogen Receptor/ERR	Inflammation/Immunology
α-Zearalenol is a Mycotoxin with high affinity for the estrogen receptors (ER), α-Zearalenol is the derivative of zearalenone (ZEN), causes reproductive disorders in animals, due to its xenoestrogenic effects.

HY-14959

Ulipristal CDB-3236; Deacetyl CDB-2914	Progesterone Receptor	Cancer Endocrinology
Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system.

HY-N6740

Beta-Zearalanol	Apoptosis	Metabolic Disease
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid.

HY-N11346

Echis Ocellatus Venom West African Carpet Viper Venom	Others	Inflammation/Immunology
Echis Ocellatus Venom (West African Carpet Viper Venom) is a snake venom that can be obtained from West African Carpet Viper. Echis Ocellatus Venom can induce reproductive dysfunction in male by oxidative stress and pro-Inflammatory cytokines.

HY-D0342

Disperse Red 1
Fluorescent Dye Others

Disperse Red 1, an azobenzene derivative, is an azo textile dye extensively used for dyeing polyester fabrics in textile industry.

Disperse Red 1	Fluorescent Dye	Others
Disperse Red 1, an azobenzene derivative, is an azo textile dye extensively used for dyeing polyester fabrics in textile industry.

HY-B0806

Proguanil	Parasite Antifolate	Infection
Proguanil, an antimalarial prodrug, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase (DHFR) inhibitor.

HY-B0806A

Proguanil hydrochloride	Parasite Antifolate	Infection
Proguanil hydrochloride, an antimalarial prodrug, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.

HY-P1197

Kisspeptin-10, rat	Kisspeptin Receptor	Inflammation/Immunology Cardiovascular Disease
Kisspeptin-10, rat is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, rat is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound.

HY-P1197A

Kisspeptin-10, rat TFA	Kisspeptin Receptor	Inflammation/Immunology Cardiovascular Disease
Kisspeptin-10, rat TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, rat TFA is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 TFA reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound.

HY-B1066

Butylhydroxyanisole Butylated hydroxyanisole; BHA; E320	Reactive Oxygen Species Ferroptosis	Inflammation/Immunology Neurological Disease
Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development. Butylhydroxyanisole is a ferroptosis inducer.

HY-N6678

Zearalanone	Estrogen Receptor/ERR	Endocrinology
Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system.

HY-P3069

γ-Neuropeptide (rabbit)	Neurokinin Receptor	Endocrinology Neurological Disease
γ-Neuropeptide (rabbit) can be isolated from rabbit intestine. γ-Neuropeptide is an endogenous neurokinin peptide that acts as a neurokinin 2 (NK2) receptor agonist. γ-Neuropeptide mediates hypothalamic-pituitary-adrenal (HPA) axis, as well as reproductive hormone release.

HY-18260

Bisphenol A	Endogenous Metabolite	Endocrinology
Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders.

HY-P2315

Human β-defensin-1 HβD-1	Antibiotic Bacterial	Infection
Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria.

HY-N6801

Nivalenol	Caspase Bacterial Apoptosis Antibiotic	Infection Inflammation/Immunology
Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect.

HY-18260S1

Bisphenol A-d6	Endogenous Metabolite	Endocrinology
Bisphenol A-d₆ is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3].

HY-N1581

Quassin Nigakilactone D	Parasite	Infection Endocrinology
Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits *P. falciparum* with an IC₅₀ of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity.

HY-18260S

Bisphenol A-d16	Endogenous Metabolite	Endocrinology
Bisphenol A-d₁₆ is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].

HY-18260S4

Bisphenol A-d4	Endogenous Metabolite	Endocrinology
Bisphenol A-d₄ is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].

HY-18260S5

Bisphenol A-d4-1	Endogenous Metabolite	Endocrinology
Bisphenol A-d₄-1 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].

HY-18260S3

Bisphenol A-4d	Endogenous Metabolite	Endocrinology
Bisphenol A-d₈ is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3][4].

HY-143546

RET-IN-9	RET	Cancer
RET-IN-9 is a potent inhibitor of RET. RET kinase is a single-pass transmembrane receptor tyrosine kinase that plays an important role in the development of the kidney and enteric nervous system, and the maintenance of homeostasis in the nervous, endocrine, hematopoietic, and male reproductive systems. RET-IN-9 has the potential for the research of RET-related disease including non-small cell lung cancer and medullary thyroid cancer (extracted from patent WO2021115457A1, compound 29).

HY-P2317A

Cecropin P1, porcine acetate	Bacterial Endogenous Metabolite	Infection
Cecropin P1, porcine acetate is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine acetate shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine acetate shows antiviral activity and inhibits PRRSV infection.

HY-B1904

Fluphenazine decanoate	Dopamine Receptor	Neurological Disease
Fluphenazine decanoate is a dopamine D₂ receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research.

HY-B1904A

Fluphenazine decanoate dihydrochloride	Dopamine Receptor	Neurological Disease
Fluphenazine decanoate dihydrochloride is a dopamine D₂ receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research.

HY-131384

8,11,14-Eicosatriynoic Acid 8,11,14-Icosatriynoic acid		Others
8,11,14-Eicosatriynoic Acid, as an inhibitor of prostaglandins, leukotriene biosynthesis and arachidonic acid-induced platelet aggregation, blocks human 12-lipoxygenase (12-LO), cyclooxygenation The enzyme (COX) and 5-lipoxygenase (5-LO) IC50 values were 0.46 μM, 14 μM and 25 μM, respectively. In addition, it inhibits the action of slow-reacting substances of allergic reactions with IC50 values of 10 μM [1,2]. Lipoxygenase is widely found in fungi, plants and animals, and its content is very high. 12-LO is involved in many important disease states and may play a role in oxidative glutamate toxicity. COX enzymes play complex roles in human physiology and pathology involving the neuronal, immune, renal, cardiovascular, gastrointestinal and reproductive systems. COX enzymes are blocked by aspirin and various other NSAIDs, making them clinically important [3]. 5-LO is involved in cancer pathology. It is expressed by a variety of cancer cells, including colon, lung, breast, and prostate cancers, and promotes cancer cell growth and neovascularization. In vitro: As of now, in vitro studies of 8,11,14-eicosatriynoic acid are still under development. In vivo: To date, in vivo studies of 8,11,14-eicosatriynoic acid are in the development stage. References: [1]. Goetz, J., Sprecher, H., Cornwell, D. and Panganamala, R . Inhibition of prostaglandin biosynthesis by triynoic acid. . prostaglandins. 1976;12(2):187-192. [2]. Sun, F., McGuire, J., Morton, D., Pike, J., Sprecher, H. and Kunau, W. Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds effect. prostaglandins. 1981;21(2):333-343. [3]. Fitzpatrick, F. Cyclooxygenase: regulation and function. Current Drug Design. 2004;10(6):577-588.

Cat. No.	Product Name

HY-L087

Anti-Obesity Compound Library	1988 compounds
Obesity is widely recognized as the largest and fastest growing public health problem and is associated with numerous chronic disorders including osteoarthritis, obstructive sleep apnea, gallstones, fatty liver disease, reproductive and gastrointestinal cancers, dyslipidemia, hypertension, type 2 diabetes, heart failure, coronary artery disease, stroke, etc. Although obesity has long been associated with serious health issues, it has only recently been regarded as a disease in the sense of being a specific target for medical therapy. Obesity may be viewed as the dysregulation of two physiological functions, appetite regulation and energy metabolism, which combine to create disordered energy balance. Consequently, developing obesity treatments that target novel pathways is a growing focus for both biopharmaceutical industries. MCE Anti-Obesity Compound Library owns a unique collection of 1988 compounds, which mainly target signaling pathway of controlling appetite, fatty acid metabolism and energy expenditure, etc. This library is a useful tool for discovery anti-obesity drugs.

Anti-Obesity Compound Library

1988 compounds

Obesity is widely recognized as the largest and fastest growing public health problem and is associated with numerous chronic disorders including osteoarthritis, obstructive sleep apnea, gallstones, fatty liver disease, reproductive and gastrointestinal cancers, dyslipidemia, hypertension, type 2 diabetes, heart failure, coronary artery disease, stroke, etc. Although obesity has long been associated with serious health issues, it has only recently been regarded as a disease in the sense of being a specific target for medical therapy. Obesity may be viewed as the dysregulation of two physiological functions, appetite regulation and energy metabolism, which combine to create disordered energy balance. Consequently, developing obesity treatments that target novel pathways is a growing focus for both biopharmaceutical industries.

MCE Anti-Obesity Compound Library owns a unique collection of 1988 compounds, which mainly target signaling pathway of controlling appetite, fatty acid metabolism and energy expenditure, etc. This library is a useful tool for discovery anti-obesity drugs.

Cat. No.	Product Name	Type

HY-D0342

Disperse Red 1
Dyes

Disperse Red 1, an azobenzene derivative, is an azo textile dye extensively used for dyeing polyester fabrics in textile industry.

Disperse Red 1	Dyes
Disperse Red 1, an azobenzene derivative, is an azo textile dye extensively used for dyeing polyester fabrics in textile industry.

Cat. No.	Product Name	Type

HY-131384

8,11,14-Eicosatriynoic Acid 8,11,14-Icosatriynoic acid	Biochemical Assay Reagents
8,11,14-Eicosatriynoic Acid, as an inhibitor of prostaglandins, leukotriene biosynthesis and arachidonic acid-induced platelet aggregation, blocks human 12-lipoxygenase (12-LO), cyclooxygenation The enzyme (COX) and 5-lipoxygenase (5-LO) IC50 values were 0.46 μM, 14 μM and 25 μM, respectively. In addition, it inhibits the action of slow-reacting substances of allergic reactions with IC50 values of 10 μM [1,2]. Lipoxygenase is widely found in fungi, plants and animals, and its content is very high. 12-LO is involved in many important disease states and may play a role in oxidative glutamate toxicity. COX enzymes play complex roles in human physiology and pathology involving the neuronal, immune, renal, cardiovascular, gastrointestinal and reproductive systems. COX enzymes are blocked by aspirin and various other NSAIDs, making them clinically important [3]. 5-LO is involved in cancer pathology. It is expressed by a variety of cancer cells, including colon, lung, breast, and prostate cancers, and promotes cancer cell growth and neovascularization. In vitro: As of now, in vitro studies of 8,11,14-eicosatriynoic acid are still under development. In vivo: To date, in vivo studies of 8,11,14-eicosatriynoic acid are in the development stage. References: [1]. Goetz, J., Sprecher, H., Cornwell, D. and Panganamala, R . Inhibition of prostaglandin biosynthesis by triynoic acid. . prostaglandins. 1976;12(2):187-192. [2]. Sun, F., McGuire, J., Morton, D., Pike, J., Sprecher, H. and Kunau, W. Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds effect. prostaglandins. 1981;21(2):333-343. [3]. Fitzpatrick, F. Cyclooxygenase: regulation and function. Current Drug Design. 2004;10(6):577-588.

8,11,14-Eicosatriynoic Acid

8,11,14-Icosatriynoic acid

Biochemical Assay Reagents

8,11,14-Eicosatriynoic Acid, as an inhibitor of prostaglandins, leukotriene biosynthesis and arachidonic acid-induced platelet aggregation, blocks human 12-lipoxygenase (12-LO), cyclooxygenation The enzyme (COX) and 5-lipoxygenase (5-LO) IC50 values were 0.46 μM, 14 μM and 25 μM, respectively. In addition, it inhibits the action of slow-reacting substances of allergic reactions with IC50 values of 10 μM [1,2]. Lipoxygenase is widely found in fungi, plants and animals, and its content is very high. 12-LO is involved in many important disease states and may play a role in oxidative glutamate toxicity. COX enzymes play complex roles in human physiology and pathology involving the neuronal, immune, renal, cardiovascular, gastrointestinal and reproductive systems. COX enzymes are blocked by aspirin and various other NSAIDs, making them clinically important [3]. 5-LO is involved in cancer pathology. It is expressed by a variety of cancer cells, including colon, lung, breast, and prostate cancers, and promotes cancer cell growth and neovascularization. In vitro: As of now, in vitro studies of 8,11,14-eicosatriynoic acid are still under development. In vivo: To date, in vivo studies of 8,11,14-eicosatriynoic acid are in the development stage. References: [1]. Goetz, J., Sprecher, H., Cornwell, D. and Panganamala, R . Inhibition of prostaglandin biosynthesis by triynoic acid. . prostaglandins. 1976;12(2):187-192. [2]. Sun, F., McGuire, J., Morton, D., Pike, J., Sprecher, H. and Kunau, W. Inhibition of platelet arachidonic acid 12-lipoxygenase by acetylenic acid compounds effect. prostaglandins. 1981;21(2):333-343. [3]. Fitzpatrick, F. Cyclooxygenase: regulation and function. Current Drug Design. 2004;10(6):577-588.

Cat. No.	Product Name	Target	Research Area

HY-P0243

Luteinizing Hormone Releasing Hormone (LH-RH), salmon Salmon GnRH; Salmon gonadotropin-releasing hormone; sGnRH	Peptides	Metabolic Disease
Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.

HY-P1905

[Gln8]-C517 (LH-RH), chicken	Peptides	Endocrinology
[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.

HY-P3924

Agouti-Related Protein (54-82) (human) AGRP (54-82) (human)	Peptides	Neurological Disease
Agouti-Related Protein (54-82) (human) (AGRP (54-82) (human)) is an amino-terminal 54-82 fragment of agouti-related protein (AGRP).

HY-P1197

Kisspeptin-10, rat	Kisspeptin Receptor	Inflammation/Immunology Cardiovascular Disease
Kisspeptin-10, rat is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, rat is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound.

HY-P1197A

Kisspeptin-10, rat TFA	Kisspeptin Receptor	Inflammation/Immunology Cardiovascular Disease
Kisspeptin-10, rat TFA is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, rat TFA is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 TFA reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound.

HY-P3069

γ-Neuropeptide (rabbit)	Neurokinin Receptor	Endocrinology Neurological Disease
γ-Neuropeptide (rabbit) can be isolated from rabbit intestine. γ-Neuropeptide is an endogenous neurokinin peptide that acts as a neurokinin 2 (NK2) receptor agonist. γ-Neuropeptide mediates hypothalamic-pituitary-adrenal (HPA) axis, as well as reproductive hormone release.

HY-P2315

Human β-defensin-1 HβD-1	Antibiotic Bacterial	Infection
Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria.

HY-P2317A

Cecropin P1, porcine acetate	Bacterial Endogenous Metabolite	Infection
Cecropin P1, porcine acetate is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine acetate shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine acetate shows antiviral activity and inhibits PRRSV infection.

Cat. No.	Product Name	Target	Category

HY-127170

3-Hydroxycoumarin	Lipoxygenase	Phenylpropanoids Coumarins Classification of Application Fields Disease Research Fields Other Diseases Source classification Plants other families
3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage.

HY-N6740

Beta-Zearalanol	Apoptosis	Phenols Polyphenols Antibiotics Macrolide Antibiotics Classification of Application Fields Disease Research Fields Metabolic Disease Source classification Microorganisms
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid.

HY-N11346

Echis Ocellatus Venom West African Carpet Viper Venom	Others	Snake Venoms Animals Animal Venoms
Echis Ocellatus Venom (West African Carpet Viper Venom) is a snake venom that can be obtained from West African Carpet Viper. Echis Ocellatus Venom can induce reproductive dysfunction in male by oxidative stress and pro-Inflammatory cytokines.

HY-N6678

Zearalanone	Estrogen Receptor/ERR	Phenols Polyphenols Antibiotics Macrolide Antibiotics Classification of Application Fields Disease Research Fields Endocrinology Source classification Microorganisms
Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor, Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system.

HY-18260

Bisphenol A	Endogenous Metabolite	Phenols Polyphenols Classification of Application Fields Disease Research Fields Endocrinology Source classification Endogenous metabolite
Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders.

HY-N6801

Nivalenol	Caspase Bacterial Apoptosis Antibiotic	Sesquiterpenes Terpenoids Inflammation/Immunology Infection Disease Research Fields Classification of Application Fields Source classification Microorganisms
Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect.

HY-N1581

Quassin Nigakilactone D	Parasite	Terpenoids Triterpenes Classification of Application Fields Disease Research Fields Endocrinology Source classification Plants Simaroubaceae Picrasma quassioides(D．Don)Benn．
Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits *P. falciparum* with an IC₅₀ of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity.

Cat. No.	Product Name

HY-18260S1

Bisphenol A-d6

Bisphenol A-d₆ is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3].

HY-18260S

Bisphenol A-d16

Bisphenol A-d₁₆ is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].

HY-18260S4

Bisphenol A-d4

Bisphenol A-d₄ is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].

HY-18260S5

Bisphenol A-d4-1

Bisphenol A-d₄-1 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].

HY-18260S3

Bisphenol A-4d

Bisphenol A-d₈ is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3][4].

reproductive

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products