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Results for "

retrograde

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Fluorescent Dye

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-122571
    Retro-2

    		Filovirus Parasite Autophagy Infection Cancer
    Retro-2 is a selective inhibitor of retrograde protein trafficking at the endosome-trans-Golgi network interface. Retro-2 is an ebolavirus (EBOV) infection inhibitor with an EC50 of 12.2 µM in HeLa cells. Retro-2 induces cell autophagy .
    <em>Retro</em>-2
  • HY-D1161
    True Blue

    NCI 240899

    		 Fluorescent Dye Neurological Disease
    True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival .
    True Blue
  • HY-137896
    4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium

    		Fluorescent Dye Others
    4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium is a fluorescent dye. 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium can be used to demonstrate retrograde axonal transport to label secondary antibodies and as a fluorescent whole cell stain .
    4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium
  • HY-108166
    Hydroxystilbamidine

    		Fluorescent Dye Inflammation/Immunology
    Hydroxystilbamidine, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine is a retrograde fluorescent tracer and a histochemical stain [1]
    Hydroxystilbamidine
  • HY-123601
    DHQZ 36

    		Parasite Infection
    DHQZ 36 is a potent inhibitor of retrograde trafficking. DHQZ 36 inhibits Leishmania amazonensis infection in macrophages with an EC50 of 13.63 μM. DHQZ 36 has potent anti-parasite activity .
    DHQZ 36
  • HY-114698
    Retro-2 cycl

    RN 1-001

    		 Virus Protease Arenavirus HPV Infection
    Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC50s of 54 μM and 160 μM, respectively . Antiviral agent .
    <em>Retro</em>-2 cycl
  • HY-101884
    Biocytin
    1 Publications Verification

    (+)-Biocytin

    		 Endogenous Metabolite Neurological Disease
    Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the ϵ-amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays .
    Biocytin
  • HY-P1446
    Cholera toxin
    5+ Cited Publications

    Choleragen

    		 Adenylate Cyclase Inflammation/Immunology
    Cholera toxin (Choleragen), an AB(5)-subunit toxin, enters host cells by binding the ganglioside GM1 at the plasma membrane (PM) and travels retrograde through the trans-Golgi Network into the endoplasmic reticulum (ER) . Choleragen activates adenylate cyclase by catalyzing ADP-ribosylation of Gs alpha, the stimulatory guanine nucleotide-binding protein .
    Cholera toxin

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