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Results for "

seed

" in MCE Product Catalog:

142

Inhibitors & Agonists

1

Biochemical Assay Reagents

122

Natural
Products

10

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas
  • HY-N7072
    Grape seed extract

    Apoptosis Cancer Metabolic Disease Inflammation/Immunology
    Grape seed extract is a natural product, with anti-inflammatory and anti-proliferative effects. Grape seed extract shows inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase. Grape seed extract induces apoptotic in human colorectal cancer cells.
  • HY-N10343
    epi-Progoitrin

    Others Others
    epi-Progoitrin is the major thioglucoside of Crambe abyssinica seed.
  • HY-107210
    Avenasterol

    Others Others
    Avenasterol is a natural sterol isolated from seed oils of Testouri and Jebali cultivars.
  • HY-W008927A
    (Z)-Fluoxastrobin

    Fungal Infection
    (Z)-Fluoxastrobin is fungicide agent. (Z)-Fluoxastrobin has excellent control of important seed and soilborne pathogens.
  • HY-N10369
    1,2,3,7-Tetrahydroxy-8-methoxy-6-methyl-9,10-anthraquinone

    Others Others
    1,2,3,7-Tetrahydroxy-8-methoxy-6-methyl-9,10-anthraquinone is an anthraquinone compound isolated from the seeds of Cassia obtusifolia.
  • HY-N3761
    Dimethylmatairesinol

    (-)-Maculatin; Methylarctigenin

    Others Others
    Dimethylmatairesinol (compound 8) is a lignan compound isolated from the seed of Hernandia nymphaeifolia. Dimethylmatairesinol shows cytotoxicity against the KKU-M156 and HepG2 cell line with IC50s of 5.4 μM (Emax 59%) and 5.2 μM (Emax 78%), respectively.
  • HY-N4073
    6"-O-Malonyldaidzin

    Others Inflammation/Immunology
    6"-O-Malonyldaidzin is a malonylated isoflavone isolated from soybean seeds. 6"-O-Malonyldaidzin may has protective effect on eye.
  • HY-N9454
    Garcinoic acid

    Others Cancer
    Garcinoic acid is the vitamin E analogue extracted from Garcinia Kola seeds. Garcinoic acid shows a marked antiproliferative effect on glioma C6 cancer cells.
  • HY-N7443
    Gibberellin A1

    Others Others
    Gibberellin A1 is a kind of plant hormones. Gibberellin A1 is a growth-promoting acids isolated from immature seed of Phaseolus multiflorus.
  • HY-136240
    Tioxazafen

    Parasite Infection
    Tioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton.
  • HY-139066
    Punicic acid

    Trichosanic acid

    Others Metabolic Disease
    Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated α-linolenic acid and a ω-5 polyunsaturated fatty acid. Punicic acid has the potential for the research of various chronic diseases.
  • HY-N0728
    α-Linolenic acid

    PI3K Akt Cancer Cardiovascular Disease
    α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.
  • HY-N8486
    β-Escin

    Others Cardiovascular Disease
    β-Escin is the major active compound of Aesculus hippocastanum L. seeds. β-Escin exerts inhibitory effect on the basic fibroblast growth factor (bFGF)-induced proliferation, migration and tube formation, as well as CAM angiogenesis in vivo. β-Escin has the potential for the research of studying the molecular mechanism underlying the anti-angiogenic effect.
  • HY-N7604
    Isorubrofusarin-6-O-β-gentiobioside

    Isorubrofusarin gentiobioside

    Others Others
    Isorubrofusarin-6-O-β-gentiobioside (Isorubrofusarin gentiobioside) is a naphthopyrone glycoside isolated from Cassia obtusifolia Linn seeds.
  • HY-115051
    2-Hydroxymethyltetrahydropyran

    Others Others
    2-Hydroxymethyltetrahydropyran is a volatile compound in Sambucus williamsii (SW) seed oil. SW seed oil has potential antioxidant activity.
  • HY-B2053
    Tolclofos-methyl

    Bacterial Infection
    Tolclofos-methyl is a broad-spectrum aromatic hydrocarbon fungicide that is used as a see treatment for protection against soil-borne and seed borne fungal pathogens that caused seed decay and seedling blights.
  • HY-N5119
    Kaempferol-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside

    Others Others
    Kaempferol-3-O-(2''-O-β-D-glucopyl)-β-D-rutinoside is a natural glycoside that could be found in Camellia oleifera seeds.
  • HY-B2064
    Carboxin

    Carboxine; Fenoxan

    Fungal Antibiotic Infection
    Carboxin (Carboxine) is a systemic agricultural fungicide and seed protectant.
  • HY-N7055
    Trierucin

    Endogenous Metabolite Metabolic Disease
    Trierucin is a trierucic acid triglyceride from the seed oil.
  • HY-N2834
    Akuammiline

    Others Cancer
    Akuammiline, is isolated from the seeds of Picralima klaineana.
  • HY-N6999
    Soyasaponin Ac

    Others Metabolic Disease
    Soyasaponin Ac is a triterpenoid isolated from the seeds of Glycine max.
  • HY-N2249
    Hosenkoside A

    Others Inflammation/Immunology
    Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina.
  • HY-N2243
    Hosenkoside K

    Others Inflammation/Immunology
    Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina.
  • HY-N2241
    Hosenkoside F

    (+)-Hosenkoside F

    Others Inflammation/Immunology
    Hosenkoside F is a baccharane glycoside isolated from the seeds of impatiens balsamina.
  • HY-N2244
    Hosenkoside M

    (+)-Hosenkoside M

    Others Inflammation/Immunology
    Hosenkoside M is a baccharane glycoside isolated from the seeds of impatiens balsamina.
  • HY-121236
    Bavachromene

    Others Others
    Bavachromene is a chromenochalcone from the seeds of Psoralea corylifolia with estrogenic activities .
  • HY-N2250
    Hosenkoside B

    Others Inflammation/Immunology
    Hosenkoside B is a baccharane glycoside isolated from the seeds of impatiens balsamina.
  • HY-107246
    Segetalin A

    Vaccarin D

    Others Others
    Segetalin A is the compound isolated from the seeds of Vaccaria hispanica.
  • HY-N7189
    Yadanzioside C

    Others Cancer
    Yadanzioside C is a quassinoid glucoside found in seeds of Brucea amarissima.
  • HY-N2186
    Leucoside

    Others Others
    Leucoside is a natural compound isolated from tea seed extract.
  • HY-N0764
    Isobergapten

    Others Inflammation/Immunology
    Isobergapten is an allelopathic inhibitor isolated from seeds of Hevacleum laciniatum.
  • HY-N5001
    Euphorbia Factor L2

    Apoptosis Cancer
    Euphorbia factor L2, a lathyrane diterpenoid isolated from caper euphorbia seed (the seeds of Euphorbia lathyris L.), has been traditionally applied to treat cancer. Euphorbia factor L2 shows potent cytotoxicity and induces apoptosis via a mitochondrial pathway.
  • HY-N0235
    Bakuchiol

    (S)-(+)-Bakuchiol

    p38 MAPK Autophagy Cancer
    Bakuchiol is a phytoestrogen isolated from the seeds of Psoralea corylifolia L; has anti-tumor effects.
  • HY-N2251
    Hosenkoside C

    Others Others
    Hosenkoside C is a baccharane glycoside isolated from the seeds of Impatiens balsamina.
  • HY-N8119
    Euphorbia factor L8

    Others Others
    Euphorbia factor L(8) is a diterpenoid from the seeds of Euphorbia lathyris.
  • HY-N2495A
    (R)-Isomucronulatol

    (-)-Isomucronulatol; 2H-1-Benzopyran-7-ol

    Others Others
    (R)-Isomucronulatol is a natural flavonoid that could be isolated from the seeds of sphaerophysa salsula.
  • HY-N2524
    Camelliaside A

    Others Inflammation/Immunology
    Camelliaside A is a flavonoid from the methanol extract of tea (Camellia oleifera) seed pomace.
  • HY-N3852
    Erysotrine

    Bacterial Infection
    Erysotrine, isolated from seed pods of Erythrina latissima, shows antibacterial activities.
  • HY-N1276
    Secoisolariciresinol Monoglucoside

    Others Neurological Disease
    Secoisolariciresinol Monoglucoside is a natural product isolated from the seeds of Linum usitatissimum L..
  • HY-N7026
    Celosin I

    Others Metabolic Disease
    Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice.
  • HY-N8121
    Euphorbia factor L7a

    Others Others
    Euphorbia factor L7a, as a natural product, is a diterpenoid from the seeds of Euphorbia lathyris.
  • HY-N2605
    Camelliaside B

    Others Inflammation/Immunology
    Camelliaside B is a flavonoid from the methanol extract of tea (Camellia oleifera) seed pomace.
  • HY-N0750
    Monocrotaline

    Crotaline

    Others Metabolic Disease Cancer
    Monocrotaline is an pyrrolizidine alkaloid extracted from the seeds of the Crotalaria spectabilis plant to induce pulmonary hypertension in rodents.
  • HY-N5062
    7,22,25-Stigmastatrienol

    Others Others
    7,22,25-Stigmastatrienol is one of sterols of Berrettina pumpkin seed oil.
  • HY-N4132
    17-Hydroxyisolathyrol

    Others Infection Inflammation/Immunology
    17-Hydroxyisolathyrol is a macrocychc lathyrol derivative isolated from seeds of Euphorbla luthyrrs.
  • HY-W040264
    24,25-Dihydrolanosterol

    Lanostenol

    Others Others
    24,25-Dihydrolanosterol (Lanostenol) is a component of the seeds of red pepper (Capsicum annuum).
  • HY-N1605
    17α-Neriifolin

    Others Others
    17α-Neriifolin is a compound isolated from a methylene chloride extract of the seeds of Cerbera odollam.
  • HY-N6873
    GL3

    Others Others
    GL3, the major component of O. fragrans seeds, is a derivative based on both phenylethanoid and methyloleoside.
  • HY-N1436
    L-(+)-Abrine

    L-Abrine; L-N-Methyltryptophan; N-α-Methyl-L-tryptophan

    Others Inflammation/Immunology
    L-(+)-Abrine, a lethal albumin found in Abrus precatorius seeds, is an acute toxic alkaloid and chemical marker for abrin.
  • HY-N0428
    Obacunone

    Apoptosis Cancer
    Obacunone, isolated from seeds of Marsh White grapefruit, exhibits anti-tumor activity by the induction of apoptosis.
  • HY-W067358
    2-Methylpyrazine

    Others Others
    2-Methylpyrazine is a kind of alkylpyrazine that can be identified in roasted red pepper seed oils.
  • HY-W007140
    2-Hydroxymethyl-5-hydroxypyridine

    Others Others
    2-Hydroxymethyl-5-hydroxypyridine is isolated from the the matured, ripened and dried seeds of S. lychnophora.
  • HY-N2046
    Jujuboside D

    Jujuboside A1

    Others Others
    Jujuboside D (Jujuboside A1) is a dammarane-type saponin that can be isolated from the seeds of Ziziphus jujube.
  • HY-N4177
    Rubrofusarin gentiobioside

    Others Metabolic Disease
    Rubrofusarin gentiobioside is isolated from the seeds of Cassia tora L. Rubrofusarin gentiobioside has a radical scavenging effect.
  • HY-N2242
    Hosenkoside G

    Others Cancer
    Hosenkoside G, a baccharane glycoside isolated from the seeds of Impatiens Balsamina L., possesses anti-tumor activity.
  • HY-N7832
    Petunidin-3-O-glucoside chloride

    Others Metabolic Disease
    Petunidin-3-O-glucoside chloride is a flavonoid isolated from Phaseolus vulgaris L. seed, has antioxidant activity
  • HY-W015580
    (+)-Fenchone

    Others Others
    (+)-Fenchone exists in fennel seed oil (Foenicufum vulgare Mill.) and in the oil of Lavandula stoechas. Fenchone is used as a flavor in foods and in perfumery.
  • HY-N0015
    Astragalin

    Astragaline; 3-Glucosylkaempferol; Kaempferol 3-β-D-glucopyranoside

    Apoptosis Inflammation/Immunology Cancer
    Astragalin (kaempferol-3-O-glucoside) is a flavonoid with anti-inflammatory activity and newly found in persimmon leaves and green tea seeds.
  • HY-121481
    Cucurbitadienol

    10α-Cucurbitadienol

    Others Inflammation/Immunology
    Cucurbitadienol (10α-Cucurbitadienol) is a natural product that can be found in the seeds of Trichosanthes kirilowii. Cucurbitadienol exhibits anti-inflammatory effect.
  • HY-107227
    12-O-Tiglylphorbol-13-isobutyrate

    Others Others
    12-O-Tiglylphorbol-13-isobutyrate is a phorbol diester constituent of Croton tiglium L. seed oil (croton oil).
  • HY-N7640
    Deoxylimonin

    Others Cancer Inflammation/Immunology
    Desoxylimonin is a triterpenoid compound isolated from grapefruit seed. Desoxylimonin derivatives has better anticancer, analgesic and anti-inflammatory activitythan the lead compound.
  • HY-N0556
    Isoescin IA

    HIV Protease Infection
    Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity.
  • HY-B0647
    Butylphthalide

    3-n-Butylphthalide; 3-Butylphthalide

    Others Neurological Disease
    Butylphthalide(3-n-Butylphthalide) is an anti-cerebral-ischemia drug; first isolated from the seeds of celery, showed efficacy in animal models of stroke.
  • HY-N4179
    Aurantio-obtusin β-D-glucoside

    Glucoaurantio-obtusin

    Others Metabolic Disease
    Aurantio-obtusin β-D-glucoside (Glucoaurantio-obtusin), isolated from Cassiae Semen (seeds of Cassia tora), is a glucoside of aurantio-obtusin.
  • HY-N7401
    Entadamide-A-β-D-glucopyranoside

    Others Others
    Entadamide-A-β-D-glucopyranoside is one of the major components in the seeds of Entada phaseoloides. Entadamide-A-β-D-glucopyranoside has anti-complement activitie.
  • HY-133589
    Fulvine

    Others Metabolic Disease Cardiovascular Disease
    Fulvine is a pyrrolizidine alkaloid isolated from the seeds of Crotalaria fulva. Fulvine is hepatotoxic and can be used to induce hypertensive pulmonary vascular disease in vivo.
  • HY-N1470
    Plantagoside

    Others Metabolic Disease
    Plantagoside, isolated from the seeds of Plantago asiatica, is a specific and non-competitive inhibitor for jack bean α-mannosidase, with an IC50 of 5 μM.
  • HY-118115
    Pyrabactin

    Others Others
    Pyrabactin is a seed-selective abscisic acid (ABA) agonist that acts through Pyrabactin Resistance 1 (PYR1). Pyrabactin is used as a synthetic plant growth inhibitor.
  • HY-N5093
    Glucodigifucoside

    Others Cancer
    Glucodigifucoside, a cardenolide glycoside that could be isolated from the seeds of Digitalis purpurea, exhibits potent cytotoxicity against human renal adenocarcinoma cell line ACHN.
  • HY-B2033
    Pyrimethanil

    Fungal Infection
    Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection.
  • HY-N7603
    Rubrofusarin triglucoside

    Monoamine Oxidase Neurological Disease
    Rubrofusarin triglucoside is a glycoside compound isolated from Cassia obtusifolia Linn seeds. Rubrofusarin triglucoside inhibits human monoamine oxidase A (hMAO-A) with an IC50 of 85.5 μM.
  • HY-118824A
    N-Feruloylserotonin

    (E/Z)-Moschamine

    Others Cardiovascular Disease
    N-Feruloylserotonin, an antioxidative component and bioactive serotonin derivative, from the Seed of Carthamus tinctorius L., ameliorates atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.
  • HY-N0779A
    Silybin

    Apoptosis Cancer Inflammation/Immunology
    Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity.
  • HY-N0233
    Bavachin

    Corylifolin

    Estrogen Receptor/ERR Cancer
    Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
  • HY-N8405
    Isolimonexic acid

    Aromatase Cancer
    Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties.
  • HY-N0555
    Escin IB

    Others Metabolic Disease
    Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity.
  • HY-N2618
    3-​O-​Acetyloleanolic acid

    Apoptosis Cancer
    3-O-Acetyloleanolic acid (3AOA), an oleanolic acid derivative isolated from the seeds of Vigna sinensis K., induces in cancer and also exhibits anti-angiogenesis activity.
  • HY-B2114
    Escin

    Apoptosis Inflammation/Immunology Cancer
    Escin, a natural compound of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.
  • HY-N9165
    15,16-Epoxy-12R-hydroxylabda-8(17),13(16),14-triene

    Others Others
    15,16-Epoxy-12R-hydroxylabda-8(17),13(16),14-triene is a compound isolated from the seeds of Aframomum aulacocarpos.
  • HY-N4309
    Lotusine

    Others Cardiovascular Disease
    Lotusine is a pure alkaloid extracted from the green seed embryo of Nelumbo nucifera Gaertn. Lotusine shows effects on the action potentials in myocardium and slow inward current in cardiac Purkinje fibers.
  • HY-N3916
    Galanolactone

    (+)-Galanolactone

    Fungal Infection
    Galanolactone is a natural product that can be isolated from the seeds of Alpinia galanga. Galanolactone shows antifungal activitie. Galanolactone shows cytotoxicity against KB cells with an EC50 of 38.5 µg/ml.
  • HY-N1964
    Gibberellic acid

    Gibberellin A3

    Others Others
    Gibberellic Acid is named after a fungus Gibberella fujikuroi . Gibberellic Acid regulates processes of plant development and growth, including seed development and germination, stem and root growth, cell division, and flowering time.
  • HY-123026
    Salannin

    Bacterial Infection
    Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria.
  • HY-N0053
    Psoralen

    Ficusin

    Apoptosis HIV Influenza Virus Cancer
    Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al.
  • HY-123918
    JMS-17-2

    Others Cancer Endocrinology
    JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 impairs metastatic seeding and colonization of breast cancer cells.
  • HY-N6931
    Usaramine

    Bacterial Infection
    Usaramine is a pyrrolizidine alkaloid isolated from seeds of Crolatalaria pallida. Usaramine demonstrates a highlighted antibiofilm activity against Staphylococcus epidermidis by reducing more than 50% of biofilm formation without killing the bacteria.
  • HY-123918A
    JMS-17-2 hydrochloride

    Others Cancer Endocrinology
    JMS-17-2 hydrochloride is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 hydrochloride impairs metastatic seeding and colonization of breast cancer cells.
  • HY-N7628
    Cassiaside C

    Toralactone 9-O-β-D-gentiobioside

    Endogenous Metabolite Metabolic Disease
    Cassiaside C (Toralactone 9-O-β-D-gentiobioside) is a naphthopyrone isolated from the seed of Cassia tora and has inhibitory activity on advanced glycation end products (AGE) formation in vitro.
  • HY-N0770
    Isoliensinine

    Apoptosis Cancer Inflammation/Immunology
    Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells.
  • HY-N4210
    Yadanziolide A

    Others Cancer Infection
    Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects.
  • HY-129459
    α-Tocotrienol

    Others Endogenous Metabolite Neurological Disease Cardiovascular Disease
    α-Tocotrienol is an isoform of vitamin E and found in vegetables, fruits, seeds, nuts, grains, and oils. Vitamin E plays a role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection.
  • HY-107248
    Escin IIa

    Others Inflammation/Immunology
    Escin IIa, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIa has gastroprotections on ethanol-induced gastric mucosal lesions in rats.
  • HY-N6858
    4-Hydroxyisoleucine

    4-​Hydroxy-​L-​isoleucine

    Others Metabolic Disease
    4-Hydroxyisoleucine (4-​Hydroxy-​L-​isoleucine) is an amino acid which can be extracted and purified from fenugreek seeds. 4-Hydroxyisoleucine (4-​Hydroxy-​L-​isoleucine) displays an insulinotropic activity of great interest.
  • HY-N0034
    Arctiin

    Arctii; NSC 315527; Arctigenin-4-glucoside

    Others Cancer
    Arctiin(NSC 315527), a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis.
  • HY-N1404
    Sodium aescinate

    NF-κB Cancer Inflammation/Immunology
    Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.
  • HY-122778
    δ-Tocotrienol

    Others Cancer Neurological Disease Cardiovascular Disease
    δ-Tocotrienol is a Vitamin E in vegetables, fruits, seeds, nuts, grains and oils. Vitamin E has become well known for its role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection.
  • HY-107247
    Escin IIb

    Others Inflammation/Immunology
    Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions.
  • HY-N2581
    Phytic acid sodium salt

    myo-Inositol, hexakis(dihydrogen phosphate) sodium salt; Inositol hexaphosphate sodium salt

    Endogenous Metabolite Others
    Phytic acid sodium salt (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphat) is often present in legume seeds with antinutritional effects. Phytic acid sodium salt is a [PO4] 3- storage depot and precursor for other inositol phosphates and pyrophosphates. phytic acid is hydrolyzed by phytases in a stepwise manner in the plant.
  • HY-N3015
    Bruceine E

    Others Metabolic Disease
    Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ)-induced diabetic rats at lower dose.
  • HY-N9506
    Anisatin

    GABA Receptor Neurological Disease
    Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10 μM.
  • HY-N7038
    Phytohemagglutinin

    PHA-M

    Others Inflammation/Immunology
    Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, accumulates in the parenchyma cells of the cotyledons. Phytohemagglutinin is a T-cell activator. Stimulation of human mononuclear leukocytes by Phytohemagglutinin induces the expression of ChAT mRNA, and potentiated ACh synthesis.
  • HY-N6884
    Bixin

    Reactive Oxygen Species Cancer Inflammation/Immunology Cardiovascular Disease
    Bixin (BX), isolated from the seeds of Bixa orellana, is a carotenoid, possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation.
  • HY-N6057
    Obtusin

    Monoamine Oxidase Neurological Disease
    Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15 μM. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression.
  • HY-N0651
    Spinosin

    Others Neurological Disease
    Spinosyn a C-glycoside flavonoid isolated from the seeds of Zizyphus jujube, with neuroprotective effects. Spinosin inhibits Aβ1-42 production and aggregation via activating Nrf2/HO-1 pathway.
  • HY-N0720
    Neobavaisoflavone

    Apoptosis DNA/RNA Synthesis Cancer
    Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation.
  • HY-N2203
    Vitexin2''-​O-​p-​coumarate

    Others Others
    Vitexin2''-O-p-coumarate is isolated from fenugreek seeds. Vitexin2''-O-p-coumarate strongly promotes 2BS cell proliferation induced by H2O2.
  • HY-N7148
    γ-Tocopherol

    D-γ-Tocopherol; (+)-γ-Tocopherol

    COX Cancer Inflammation/Immunology
    γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity.
  • HY-N2160
    6‴-Feruloylspinosin

    Others Neurological Disease
    6‴-Feruloylspinosin is a flavonoid isolated from seeds of Ziziphus jujuba. 6‴-Feruloylspinosin can across the blood-brain barrier and enhance the expression of GABAAα1, GABAAα5, and GABABR1 mRNA in rat hippocampal neurons.
  • HY-N0484
    Liensinine

    Autophagy Mitophagy Apoptosis Cancer Cardiovascular Disease
    Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc.
  • HY-N7598
    Chrysophanol-1-O-β-gentiobioside

    Monoamine Oxidase Neurological Disease
    Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside isolated from Cassia obtusifolia seeds. Chrysophanol-1-O-β-gentiobioside shows selective inhibition of hMAO-A isozyme activity (IC50=96.15 μM).
  • HY-W098556
    4-Hydroxyhygric acid

    Others Infection
    4-Hydroxyhygric acid is a compound isolated from leaves of five species of the leguminous tropical tree Copuiferq. 4-Hydroxyhygric acid is the inhibitor of larval development of the seed-feeding bruchid beetle Callosobruchus maculatus and to have significant feeding deterrence of the leaf-feeding lepidopteran Spodoprera littoralis.
  • HY-N7109
    Erucic acid

    PI3K Endogenous Metabolite Neurological Disease
    Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia .
  • HY-N0479
    Licarin B

    (-)-Licarin B

    PPAR GLUT Metabolic Disease
    Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway.
  • HY-N0729
    Linoleic acid

    Endogenous Metabolite Metabolic Disease Cardiovascular Disease
    Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
  • HY-N7681
    Taxifolin 7-O-β-D-glucoside

    Taxifolin 7-O-glucoside

    Others Others
    Taxifolin 7-O-β-D-glucoside (Taxifolin 7-O-glucoside) is one of the main metabolites at the seed germination stage in Scutellaria baicalensis. Taxifolin 7-O-β-D-glucoside, a flavonoid, mainly exists in the episperm and participates in defending against pathogens and UV-damage.
  • HY-N7437
    Akuammidine

    Opioid Receptor Inflammation/Immunology Neurological Disease
    Akuammidine, isolated from the seeds of Picralima nitida, shows a preference for μ-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 μM at μ-, σ- and κ-opioid binding sites, respectively. Akuammidine possesses anti-inflammatory and anti-asthmatic properties.
  • HY-N2098
    Obtusifolin

    NF-κB Cancer
    Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein.
  • HY-N7384
    Vitamin B15

    Pangamic Acid

    Others Cancer Metabolic Disease Inflammation/Immunology Neurological Disease
    Vitamin B15 (Pangamic Acid) is a natural, ubiquitously in plant seeds substance and can used be as an agent stimulating cellular respiration. Vitamin B15 contains D-gluconodimethyl amino acetic acid. Vitamin B15 is also a immune-correcting agent. Vitamin B15 can be used for wide range of diseases.
  • HY-N2450
    Sulforaphene

    Apoptosis EGFR ERK NF-κB Cancer
    Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.
  • HY-N0814B
    Hexasodium phytate

    Phytic acid hexasodium; SNF-472; Hexasodium fytate

    Others Inflammation/Immunology Neurological Disease
    Hexasodium phytate (Phytic acid hexasodium) is a phosphorus storage compound of seeds and cereal grains. Hexasodium phytate has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Hexasodium phytate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
  • HY-N7140
    Gamma-Linolenic acid

    γ-Linolenic acid

    Endogenous Metabolite Metabolic Disease
    Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from human milk and several botanical seed oils. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease.
  • HY-N5077
    Sinapine

    AChE P-glycoprotein Cancer Inflammation/Immunology Neurological Disease
    Sinapine is an alkaloid isolated from seeds of the cruciferous species. Sinapine exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease.
  • HY-133108
    Azadirachtin B

    Parasite Phosphatase Influenza Virus Cancer Infection Metabolic Disease Inflammation/Immunology
    Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica. Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties.
  • HY-N0814
    Phytic acid

    Inositol hexaphosphate; myo-Inositol, hexakis(dihydrogen phosphate)

    Xanthine Oxidase Endogenous Metabolite Inflammation/Immunology Neurological Disease
    Phytic acid is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
  • HY-N5077B
    Sinapine hydroxide

    AChE P-glycoprotein Cancer Inflammation/Immunology Neurological Disease
    Sinapine hydroxide is an alkaloid isolated from seeds of the cruciferous species. Sinapine hydroxide exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine hydroxide is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease.
  • HY-N0450
    Sinapine thiocyanate

    P-glycoprotein AChE Cancer
    Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species. Sinapine thiocyanate exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease.
  • HY-N0814A
    Phytic acid dodecasodium salt hydrate

    Inositol hexaphosphate dodecasodium salt hydrate; myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate

    Xanthine Oxidase Endogenous Metabolite Inflammation/Immunology Neurological Disease
    Phytic acid dodecasodium salt hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium salt hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
  • HY-N0729S
    Linoleic Acid-d4

    Endogenous Metabolite Metabolic Disease Cardiovascular Disease
    Linoleic Acid-d4 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
  • HY-N0729S1
    Linoleic acid-d11

    Endogenous Metabolite Metabolic Disease Cardiovascular Disease
    Linoleic acid-d11 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
  • HY-N8214
    Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside

    Others Cardiovascular Disease
    Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside is a bioactive constituent that can be found in the seeds of Lepidium apetalum Willd. Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside exhibits significant triglyceride (TG)-lowering effects in HepG2 cells.
  • HY-N0485
    Liensinine Diperchlorate

    Autophagy Mitophagy Cardiovascular Disease
    Liensinine Diperchlor​ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlor​ate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlor​ate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc.
  • HY-N0729S3
    Linoleic acid-13C1

    Endogenous Metabolite Metabolic Disease Cardiovascular Disease
    Linoleic acid-13C1 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
  • HY-129440
    N-(p-Coumaroyl) Serotonin

    PDGFR Metabolic Disease Inflammation/Immunology
    N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca 2+ release from sarcoplasmic reticulum. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research.
  • HY-N0729S2
    Linoleic acid-13C18

    Endogenous Metabolite Metabolic Disease Cardiovascular Disease
    Linoleic acid-13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
  • HY-N7148S1
    γ-Tocopherol-d4

    COX Cancer Inflammation/Immunology
    γ-Tocopherol-d4 (D-γ-Tocopherol-d4) is the deuterium labeled γ-Tocopherol. γ-Tocopherol (D-γ-Tocopherol) is a potent cyclooxygenase (COX) inhibitor. γ-Tocopherol is a naturally occurring form of Vitamin E in many plant seeds, such as corn oil and soybeans. γ-Tocopherol possesses antiinflammatory properties and anti-cancer activity.
  • HY-119309
    Sucrose octaacetate

    Others Others
    Sucrose octaacetate is an acetylated derivative of sucrose with an intensely bitter tasting and can be used as bitter tasting surrogate. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning. Sucrose octaacetate can also be used as an in situ seed and a soft template to synthesize polyaniline (PANI) nanofibers.
  • HY-N0728S
    α-Linolenic acid-d5

    PI3K Akt Cancer Cardiovascular Disease
    α-Linolenic acid-d5 is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.
  • HY-W016409
    Ethyl 3,4-dihydroxybenzoate

    Ethyl protocatechuate

    HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species NO Synthase Autophagy Apoptosis Cancer Metabolic Disease
    Ethyl 3,4-dihydroxybenzoate (Ethyl protocatechuate), an antioxidant, is a prolyl-hydroxylase inhibitor found in the testa of peanut seeds. Ethyl 3,4-dihydroxybenzoate protects myocardium by activating NO synthase and generating mitochondrial ROS. Ethyl 3,4-dihydroxybenzoate induces cell autophagy and apoptosis in ESCC cells. Ethyl 3,4-dihydroxybenzoate is a collagen synthesis inhibitor and has a bone protecting-effect.
  • HY-N0728S2
    α-Linolenic acid-d14

    PI3K Akt Cancer Cardiovascular Disease
    α-Linolenic acid-d14 is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.
  • HY-N0728S3
    α-Linolenic acid-13C18

    PI3K Akt Cancer Cardiovascular Disease
    α-Linolenic acid-13C18 is the 13C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.
  • HY-N2025
    Oroxin A

    PPAR Glucosidase Metabolic Disease
    Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence.
  • HY-N10091
    2,3-Dihydro-3α-methoxynimbolide

    Apoptosis Others
    2,3-Dihydro-3α-methoxynimbolide is a limonoid compound isolated from the extracts of bark, leaves, roots, and seeds of Azadirachta indica A. Juss. var. siamensis Valeton. 2,3-Dihydro-3α-methoxynimbolide exhibits potent cyto-toxicities against one or more cell lines. 2,3-Dihydro-3α-methoxynimbolide activates caspases-3, -8, and -9, while increases the ratio of Bax/Bcl-2. 2,3-Dihydro-3α-methoxynimbolide induces apoptosis via both mitochondrial and death receptor pathways in AZ521.