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Results for "

serine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ASCT (3) Ser/Thr Protease (54) SHMT (5) SRPK (2) 5-HT Receptor (1) Adrenergic Receptor (1) Akt (1) Amino Acid Derivatives (79) Anaplastic lymphoma kinase (ALK) (2) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (3) Antifolate (3) Apoptosis (20) ATM/ATR (2) Aurora Kinase (1) Autophagy (6) Bacterial (11) Bcl-2 Family (4) Beta-lactamase (4) Biochemical Assay Reagents (2) c-Fms (1) c-Kit (1) c-Met/HGFR (2) Calcineurin (1) Caspase (3) Cathepsin (7) CDK (9) Complement System (2) COX (3) Dengue virus (1) Dipeptidyl Peptidase (2) DNA/RNA Synthesis (1) Dopamine Transporter (1) EAAT (2) EGFR (1) Elastase (3) Endogenous Metabolite (27) Eukaryotic Initiation Factor (eIF) (1) FAAH (6) Factor Xa (5) FAK (2) Flavivirus (4) FLT3 (1) Fluorescent Dye (3) Fungal (2) GCGR (2) GSK-3 (2) HCV (2) HCV Protease (2) HDAC (1) HPV (1) HSP (2) IGF-1R (1) IKK (3) Influenza Virus (2) Insulin Receptor (2) Interleukin Related (1) Isotope-Labeled Compounds (21) JAK (1) LIM Kinase (LIMK) (1) Liposome (8) Lipoxygenase (1) MAGL (6) MAP4K (9) MAPKAPK2 (MK2) (2) mGluR (2) Mixed Lineage Kinase (2) MNK (1) Mucin (1) NF-κB (4) NO Synthase (1) PAI-1 (5) PD-1/PD-L1 (1) PDGFR (1) Penicillin-binding protein (PBP) (1) Phosphatase (4) Phosphoglycerate Dehydrogenase (PHGDH) (6) Phospholipase (2) Pim (1) PKA (2) PKC (1) Prolyl Endopeptidase (PREP) (1) PROTACs (2) Protease Activated Receptor (PAR) (3) Proteasome (1) Ras (2) RIP kinase (6) SARS-CoV (6) SGK (2) Small Interfering RNA (siRNA) (2) Thrombin (4) TMV (2) TNF Receptor (3) VEGFR (2) Virus Protease (4) Wnt (1)
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Liposome (8)

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mGluR (2)

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PROTACs (2)

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By Research Areas:

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350

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

129

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

223

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: SRPK SHMT Ser/Thr Protease STK33 ASCT Enteropeptidase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0650

L-Serine 3 Publications Verification serine	Endogenous Metabolite Bacterial	Cancer
L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-153433

Serine Hydrolase inhibitor-21	Others	Neurological Disease
Serine Hydrolase inhibitor-21 (compound 8), a pyridine, is a serine hydrolase inhibitor with a K_i of 429 nM for BuChE. Serine Hydrolase inhibitor-21 has the potential for Alzheimer's disease research .

HY-N0650S8

*L-Serine-d3* (-)-serine-d₃; (S)-serine-d₃	Endogenous Metabolite	Cancer
L-Serine-d₃ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S11

*L-Serine-d7* (-)-serine-d₇; (S)-serine-d₇	Isotope-Labeled Compounds Endogenous Metabolite
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S7

*L-Serine-d2* (-)-serine-d₂; (S)-serine-d₂	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
L-Serine-d₂ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S1

*L-Serine-13C* (-)-serine-¹³C; (S)-serine-¹³C	Endogenous Metabolite	Cancer
L-Serine- ¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S10

*L-Serine-15N* (-)-serine-¹⁵N; (S)-serine-¹⁵N	Endogenous Metabolite	Cancer
L-Serine- ¹⁵N is the ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S2

*L-Serine-1-13C* (-)-serine-1-¹³C; (S)-serine-1-¹³C	Endogenous Metabolite	Cancer
L-Serine-1- ¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S4

*L-Serine-2-13C* (-)-serine-2-¹³C; (S)-serine-2-¹³C	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
L-Serine-2- ¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S

*L-Serine-13C3* (-)-serine-¹³C₃; (S)-serine-¹³C₃	Endogenous Metabolite	Cancer
L-Serine- ¹³C₃ is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S9

*L-Serine-15N,d3* (-)-serine-¹⁵N,d₃; (S)-serine-¹⁵N,d₃	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
L-Serine- ¹⁵N,d₃ is the deuterium and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S6

*L-Serine1-13C,15N* (-)-serine-¹³C,¹⁵N; (S)-serine-¹³C,¹⁵N	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
L-Serine1- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S5

*L-Serine-13C3,15N* (-)-serine-¹³C₃,¹⁵N; (S)-serine-¹³C₃,¹⁵N	Endogenous Metabolite	Cancer
L-Serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S3

*L-Serine-13C3,15N,d3* (-)-serine-¹³C₃,¹⁵N,d₃; (S)-serine-¹³C₃,¹⁵N,d₃	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
L-Serine- ¹³C₃, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-A0183

Phosphatidylserine Phospholipids, phosphatidylserines; serine glycerophosphatides
Phosphatidylserine is a conserved anti-inflammatory and immunosuppressive signal that is highly dysregulated in the tumor microenvironment and autoimmune diseases. During apoptosis and cellular stress，the related disrupting enzymes Xkr8 and TMEM16 mediate Phosphatidylserine externalization. Phosphatidylserine externalization produces a "eat me" signal that initiates endocytosis and helps clear the body of apoptotic cells. When pathogens use Phosphatidylserine and apoptotic mimicry to evade host immune responses，targeting Phosphatidylserine strategies can stimulate immune activity .

HY-W005308

*N-BOC-DL-serine* methyl ester**	Amino Acid Derivatives	Cancer
N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity .

HY-W048674

Fmoc-Ser(Ac)-OH Fmoc-O-acetyl-L-serine	Amino Acid Derivatives	Infection
Fmoc-Ser(Ac)-OH (Fmoc-O-acetyl-L-serine) is a Serine derivative. Fmoc-Ser(Ac)-OH can be used for the preparation of broad-spectrum coronavirus membrane fusion inhibitor .

HY-W039102

N-Fmoc-N,O-dimethyl-L-serine	Amino Acid Derivatives	Cancer
N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells .

HY-Y0507

DL-Serine 1 Publications Verification
DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .

HY-131894

DL-Serine hydroxamate

Amino Acid Derivatives Others

DL-Serine hydroxamate is a serine derivative .
HY-32687A

L-Serine methyl ester hydrochloride

L-Serine methyl ester (hydrochloride) is a serine derivative .
HY-Z0711

L-Serine isopropyl ester hydrochloride

Amino Acid Derivatives Others

L-Serine isopropyl ester hydrochloride is a serine derivative .

*DL-Serine* hydroxamate**	Amino Acid Derivatives	Others
DL-Serine hydroxamate is a serine derivative .

*L-Serine* methyl ester hydrochloride**
L-Serine methyl ester (hydrochloride) is a serine derivative .

*L-Serine* isopropyl ester hydrochloride**	Amino Acid Derivatives	Others
L-Serine isopropyl ester hydrochloride is a serine derivative .

HY-W718796

*DL-Serine-15N*	Isotope-Labeled Compounds TMV	Cancer
DL-Serine- ¹⁵N is ¹⁵N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).

HY-15129

O-Phospho-L-serine L-serine O-phosphate; L-SOP	mGluR Endogenous Metabolite	Neurological Disease
O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2 .

HY-W009908

O-Benzyl-D-serine

Amino Acid Derivatives Others

O-Benzyl-D-serine is a serine derivative .
HY-W002294

(tert-Butoxycarbonyl)-D-serine

Amino Acid Derivatives Others

(tert-Butoxycarbonyl)-D-serine is a serine derivative .

O-Benzyl-D-serine	Amino Acid Derivatives	Others
O-Benzyl-D-serine is a serine derivative .

(tert-Butoxycarbonyl)-D-serine	Amino Acid Derivatives	Others
(tert-Butoxycarbonyl)-D-serine is a serine derivative .

HY-136276

DMNB-caged-Serine	Others	Others
DMNB-caged-Serine is a photocaged amino acid. DMNB-caged-Serine can be used as a catalytic residue, hydrogen bonding partner or site of post-translational modification. DMNB-caged-Serine can be used for the control of protein phosphorylation .

HY-100808S

*D-Serine-d3* (R)-serine-d₃	Isotope-Labeled Compounds	Neurological Disease
D-Serine-d₃ ((R)-Serine-d₃) is a deuterium labeled D-Serine (HY-100808). D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration .

HY-W010156

O-(tert-Butyl)-L-serine

Amino Acid Derivatives Others

O-(tert-Butyl)-L-serine is a serine derivative .

O-(tert-Butyl)-L-serine	Amino Acid Derivatives	Others
O-(tert-Butyl)-L-serine is a serine derivative .

HY-100808

D-Serine 1 Publications Verification (R)-serine
D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration .

HY-N0650S12

*L-Serine-d3,15n*	Bacterial Endogenous Metabolite	Cancer
L-Serine- ¹⁵N,d₃ is the deuterium and ¹⁵N labeled L-Serine[1]. L-Serine ((-)-Serine;(S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation[2].

HY-Y0507S

*DL-Serine-2,3,3-d3*	TMV Isotope-Labeled Compounds	Infection Cancer
DL-Serine-2,3,3-d₃ is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].

HY-W004064

N-Boc-O-Benzyl-D-serine

Amino Acid Derivatives Others

N-Boc-O-Benzyl-D-serine is a serine derivative .

N-Boc-O-Benzyl-D-serine	Amino Acid Derivatives	Others
N-Boc-O-Benzyl-D-serine is a serine derivative .

HY-124081

N-Oleoyl-L-serine	Apoptosis	Metabolic Disease
N-Oleoyl-L-Serine is an endogenous amide of long-chain fatty acids with ethanolamine (N-acyl amides). N-Oleoyl-L-Serine is a lipid regulator of bone remodeling and stimulates osteoclast apoptosis. N-Oleoyl-L-Serine can be used for antiosteoporotic drug discovery development .

HY-W142081

N-(2,4-Dinitrophenyl)-L-serine

Amino Acid Derivatives Others

N-(2,4-Dinitrophenyl)-L-serine is a serine derivative .
HY-101409A

O-Acetyl-L-serine hydrochloride

Endogenous Metabolite Metabolic Disease

O-Acetyl-L-serine hydrochloride is an endogenous metabolite.

N-(2,4-Dinitrophenyl)-L-serine	Amino Acid Derivatives	Others
N-(2,4-Dinitrophenyl)-L-serine is a serine derivative .

*O-Acetyl-L-serine* hydrochloride**	Endogenous Metabolite	Metabolic Disease
O-Acetyl-L-serine hydrochloride is an endogenous metabolite.

HY-W142092

N-Acetyl-DL-serine	Bacterial	Others
N-Acetyl-DL-serine is a hydrophobic amino acid that is synthesized in the body and can be found as a free form or as a salt with malonate, phosphate, or acetate. N-Acetyl-DL-serine has antimicrobial activity against Bacillus cereus and Staphylococcus aureus. N-Acetyl-DL-serine has also been used for the immobilization of DNA fragments on solid surfaces and can be used for protein synthesis and optical detection of DNA strands .

HY-W011354

O-tert-Butyl-N-carbobenzoxy-L-serine methyl ester

Amino Acid Derivatives Others

O-tert-Butyl-N-carbobenzoxy-L-serine methyl ester is a serine derivative .
HY-W013793

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-serine

Amino Acid Derivatives Others

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-serine is a serine derivative .

*O-tert-Butyl-N-carbobenzoxy-L-serine* methyl ester**	Amino Acid Derivatives	Others
O-tert-Butyl-N-carbobenzoxy-L-serine methyl ester is a serine derivative .

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-serine	Amino Acid Derivatives	Others
(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-serine is a serine derivative .

HY-P2942

Chymotrypsinogen	Ser/Thr Protease	Inflammation/Immunology
Chymotrypsinogen is an inactive precursor of Chymotrypsin (HY-108910). Chymotrypsin is a serine protease produced by the pancreas .

HY-147278

Manusiran

Small Interfering RNA (siRNA) Ser/Thr Protease Others

Manusiran is a potent TMPRSS6 (transmembrane protease serine 6) synthesis reducer .
HY-147278A

Manusiran sodium

Ser/Thr Protease Small Interfering RNA (siRNA) Others

Manusiran sodium is a potent TMPRSS6 (transmembrane protease serine 6) synthesis reducer .

Manusiran	Small Interfering RNA (siRNA) Ser/Thr Protease	Others
Manusiran is a potent TMPRSS6 (transmembrane protease serine 6) synthesis reducer .

Manusiran sodium	Ser/Thr Protease Small Interfering RNA (siRNA)	Others
Manusiran sodium is a potent TMPRSS6 (transmembrane protease serine 6) synthesis reducer .

HY-101409

O-Acetylserine O-Acetyl-L-serine	Endogenous Metabolite	Others
O-Acetylserine (O-Acetyl-L-serine) is an intermediate in the biosynthesis of the amino acid cysteine in bacteria and plants.

HY-W008977

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-L-serine

Amino Acid Derivatives Others

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-L-serine is a serine derivative .
HY-W008308

H-Ser(Bzl)-OH

O-Benzyl-L-serine
Amino Acid Derivatives Others

H-Ser(Bzl)-OH is a serine derivative .
HY-W022226

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-D-serine

Amino Acid Derivatives Others

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-D-serine is a serine derivative .

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-L-serine	Amino Acid Derivatives	Others
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-L-serine is a serine derivative .

H-Ser(Bzl)-OH O-Benzyl-L-serine	Amino Acid Derivatives	Others
H-Ser(Bzl)-OH is a serine derivative .

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-D-serine	Amino Acid Derivatives	Others
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-D-serine is a serine derivative .

HY-15129S

*O-Phospho-L-serine-13C3,15N* L-serine O-phosphate-¹³C₃,¹⁵N; L-SOP-¹³C₃,¹⁵N	mGluR Endogenous Metabolite	Neurological Disease
O-Phospho-L-serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].

HY-W072598

N-(tert-Butoxycarbonyl)-O-(tetrahydro-2H-pyran-2-yl)-L-serine

Amino Acid Derivatives Others

N-(tert-Butoxycarbonyl)-O-(tetrahydro-2H-pyran-2-yl)-L-serine is a serine derivative .
HY-W053702

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-D-serine

Amino Acid Derivatives Others

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-D-serine is a serine derivative .

HY-108904

Urokinase, Human urine Urokinase-type plasminogen activator; Uronase; Win 22005; Win-Kinase	Ser/Thr Protease	Cardiovascular Disease Cancer
Urokinase (peptidolytic) (EC 3.4.21.73) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0650

L-Serine 3 Publications Verification serine	Structural Classification Classification of Application Fields Anti-aging Source classification Endocrine diseases Amino acids Endogenous metabolite Microorganisms Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder Cancer	Endogenous Metabolite Bacterial
L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-15129

O-Phospho-L-serine L-serine O-phosphate; L-SOP	Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite	mGluR Endogenous Metabolite
O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2 .

HY-101409A

*O-Acetyl-L-serine* hydrochloride**	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
O-Acetyl-L-serine hydrochloride is an endogenous metabolite.

HY-101409

O-Acetylserine O-Acetyl-L-serine	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
O-Acetylserine (O-Acetyl-L-serine) is an intermediate in the biosynthesis of the amino acid cysteine in bacteria and plants.

HY-119759

Lipoxamycin	Infection Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields Other Antibiotics	Fungal
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM .

HY-134222A

N-Acetylserine N-Acetyl-L-serine	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Acetylserine (N-Acetyl-L-serine) can bind to CysB apoprotein. N-acetylserine is the physiological inducer of cysteine biosynthesis. N-Acetylserine can stimulate in vitro cysJIH transcription .

HY-N4332

Rivulariapeptolides 1121	Natural Products Microorganisms Source classification	Ser/Thr Protease
Rivulariapeptolides 1121 is a high potent and selective serine protease inhibitor with IC₅₀ values of 35.52 nM, 13.24 nM and 48.05 nM for chymotrypsin, elastase and proteinase K, respectively .

HY-113013

Hydroxypyruvic acid β-Hydroxypyruvic acid; 3-Hydroxypyruvic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxypyruvic acid (β-Hydroxypyruvic acid) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

HY-113013A

Hydroxypyruvic acid lithium hydrate β-Hydroxypyruvic acid lithium hydrate; 3-Hydroxypyruvic acid lithium hydrate	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

HY-N4331

Rivulariapeptolides 1185	Natural Products Microorganisms Source classification	Ser/Thr Protease
Rivulariapeptolides 1185 is a high potent and selective serine protease inhibitor with IC₅₀ values of 13.17 nM, 23.59 nM and 55.26 nM for chymotrypsin, elastase and proteinase K, respectively .

HY-N4333

Rivulariapeptolides 988	Natural Products Microorganisms Source classification	Ser/Thr Protease
Rivulariapeptolides 988 is a high potent and selective serine protease inhibitor with IC₅₀ values of 95.46 nM, 15.29 nM and 85.50 nM for chymotrypsin, elastase and proteinase K, respectively .

HY-18234A

Leupeptin hemisulfate Maximum Cited Publications 29 Publications Verification	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Cathepsin Ser/Thr Protease Virus Protease
Leupeptin hemisulfate is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin hemisulfate potently inhibits *serine, cysteine* and threonine proteases. Leupeptin hemisulfate inhibits M ^pro (the main protease of SARS-CoV-2) and also has anti-inflammatory activity .

HY-15130

DL-O-Phosphoserine	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-O-Phosphoserine, a normal metabolite in human biofluid, is an ester of serine and phosphoric acid.

HY-126034

3,4-Dichloroisocoumarin	Structural Classification Animals Source classification Coumarins Phenylpropanoids	Ser/Thr Protease
3,4-Dichloroisocoumarin is a potent *serine-protease* inhibitor that inhibits chymotrypsin-like activity .

HY-139568

Deutarserine CTP-692	Structural Classification Neurological Disease Classification of Application Fields Source classification Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Deutarserine is a deuterium modified analog of endogenous D-serine (CTP 692), which is used in the research of adults with schizophrenia .

HY-N4330

Rivulariapeptolides 1155	Natural Products Microorganisms Source classification	Ser/Thr Protease
Rivulariapeptolides 1155 is a potent serine protease inhibitor with IC₅₀s of 41.84, 4.94, 56.54 nM for chymotrypsin, elastase, prpteinase K, respectively .

HY-P0219

Microcystin-LA	Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	Phosphatase
Microcystin LA, a natural toxin, exerts its cytotoxic exects by inhibiting the serine-threonine protein phosphatases PP1 and PP2A with IC₅₀s of 0.3 and 0.3 nM, respectively .

HY-N10223

Phostriecin	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Inflammation/Immunology Disease Research Fields Other Antibiotics	Antibiotic Phosphatase
Phostriecin is an antitumor antibiotic produced by Streptomyces pulveraceus. Phostriecin is a strong inhibitor of type 2A (PP2A) and a weak inhibitor of type 1 (PP1) serine/threonine protein phosphatases with IC₅₀s of 3.2 nM and 131 μM, respectively. Phostriecin has the potential for the research of cancer .

HY-N1996

Chebulagic acid 2 Publications Verification	Classification of Application Fields Combretaceae Source classification Phenols Polyphenols Terminalia chebula Retz. Plants Inflammation/Immunology Disease Research Fields	COX Lipoxygenase SARS-CoV Influenza Virus
Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid is a *M2 serine* to asparagine 31 mutation (S31N) inhibitor and influenza antiviral. Chebulagic acid also against SARS-CoV-2 viral replication with an EC₅₀** of 9.76 μM.

HY-N6798

Myriocin 4 Publications Verification Thermozymocidin; ISP-I	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	HCV Antibiotic
Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC₅₀ of 3.5 µg/mL for inhibiting HCV infection .

Cat. No.	Product Name	Chemical Structure

HY-N0650S8

*L-Serine-d3*
L-Serine-d₃ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S11

*L-Serine-d7*
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S1

L-Serine-13C

L-Serine- ¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
HY-N0650S10

L-Serine-15N

L-Serine- ¹⁵N is the ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S7

*L-Serine-d2*
L-Serine-d₂ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S2

*L-Serine-1-13C*
L-Serine-1- ¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S4

*L-Serine-2-13C*
L-Serine-2- ¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S

*L-Serine-13C3*
L-Serine- ¹³C₃ is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S9

*L-Serine-15N,d3*
L-Serine- ¹⁵N,d₃ is the deuterium and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S6

*L-Serine1-13C,15N*
L-Serine1- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S5

*L-Serine-13C3,15N*
L-Serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S3

*L-Serine-13C3,15N,d3*
L-Serine- ¹³C₃, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W718796

*DL-Serine-15N*
DL-Serine- ¹⁵N is ¹⁵N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).

HY-100808S

D-Serine-d3

D-Serine-d₃ ((R)-Serine-d₃) is a deuterium labeled D-Serine (HY-100808). D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration .

HY-N0650S12

*L-Serine-d3,15n*
L-Serine- ¹⁵N,d₃ is the deuterium and ¹⁵N labeled L-Serine[1]. L-Serine ((-)-Serine;(S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation[2].

HY-Y0507S

*DL-Serine-2,3,3-d3*
DL-Serine-2,3,3-d₃ is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].

HY-15129S

*O-Phospho-L-serine-13C3,15N*
O-Phospho-L-serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].

HY-115435S

1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine-d54 sodium

1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine-d₅₄ (sodium) is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine.

HY-146820S

*1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine-d7 sodium*
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine-d₇ (sodium) is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium).

HY-146861S

*1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium*
1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d₅ (sodium) is deuterium labeled 1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

HY-146864S

*1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium*
1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d₅ (sodium) is deuterium labeled 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

HY-146865S

*1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium*
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

HY-146866S

*1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146868S

*1-Heptadecanoyl-2-oleoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-oleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-oleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146869S

*1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146870S

*1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146867S

*1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-W007941S1

Fmoc-Ser(tBu)-OH-15N

Fmoc-Ser(tBu)-OH- ¹⁵N is the ¹⁵N labeled Fmoc-Ser(tBu)-OH[1]. Fmoc-Ser(tBu)-OH is a serine derivative[2].

HY-B0190S1

Nafamostat formate salt-13C6
Nafamostat formate salt- ¹³C₆ is the ¹³C labeled Nafamostat[1]. Nafamostat, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis. Nafamostat blocks activation of SARS-CoV-2[2][3][4][5].

HY-136433S

N,N'-Dinitrosopiperazine-d8
N,N'-Dinitrosopiperazine-d₈ is the deuterium labeled N,N'-Dinitrosopiperazine[1]. N,N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine;DNP) is a carcinogen with specificity for nasopharyngeal epithelium and facilitates NPC metastasis. N,N'-Dinitrosopiperazine regulates multiple signaling pathways through protein phosphorylation, including LYRIC at serine 568[2].

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