survivin

By Targets:	Survivin (13) Akt (2) Antibiotic (1) Apoptosis (9) Arp2/3 Complex (1) Autophagy (4) Bcl-2 Family (2) Caspase (1) DNA/RNA Synthesis (1) EGFR (1) Endogenous Metabolite (1) Eukaryotic Initiation Factor (eIF) (1) Ferroptosis (1) FXR (1) HSP (2) IAP (2) JNK (1) NADPH Oxidase (1) Notch (1) Phosphatase (1) Pim (1) Reactive Oxygen Species (1) STAT (3) Wnt (2) YAP (1) β-catenin (3)
By Research Areas:	Cancer (29) Infection (2)

Targets Recommended: Survivin

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136538

LQZ-7I	Survivin	Cancer
LQZ-7I is a *survivin*-targeting inhibitor. LQZ-7I inhibits survivin dimerization. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors .

HY-122678

LQZ-7F	Survivin Apoptosis	Cancer
LQZ-7F, a survivin dimerization inhibitor, induces spontaneous apoptosis and synergizes with Docetaxel in prostate cancer cells. LQZ-7F dose-dependently inhibits survival of both PC-3 and C4-2 cells with IC₅₀s of 2.99 and 2.47 µM, respectively .

HY-162041

AQIM-I	Survivin	Cancer
AQIM-I is an inhibitor of survivin via inhibits survivin expression and colony formation. AQIM-I induces ROS production, apoptosis, cell cycle arrest, DNA damage, and autophagy. AQIM-I inhibits nonsmall cell lung cancer cells A549 with an IC₅₀ value of 9 nM .

HY-10194A

Sepantronium hydrochloride YM-155 hydrochloride	Survivin Autophagy	Cancer
Sepantronium hydrochloride (YM-155 hydrochloride) is a novel *survivin* suppressant with an IC₅₀ of 0.54 nM for the inhibition of survivin promoter activity .

HY-125964

LLP-3	Survivin	Cancer
LLP-3 is a potent *Survivin* inhibitor that disrupts the Survivin-Ran interaction in cancer cells. LLP-3 can be used in the research of Glioblastoma multiforme (GBM) .

HY-10194

Sepantronium bromide

10+ Cited Publications

YM-155
Survivin Autophagy Cancer

Sepantronium bromide (YM-155) is a survivin inhibitor with an IC₅₀ of 0.54 nM .

Sepantronium bromide 10+ Cited Publications YM-155	Survivin Autophagy	Cancer
Sepantronium bromide (YM-155) is a *survivin* inhibitor with an IC₅₀ of 0.54 nM .

HY-U00177

GDP366 1 Publications Verification	Survivin	Cancer
GDP366, a dual inhibitor of *survivin* and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells.

HY-P1750

Shepherdin (79-87)	HSP Survivin	Cancer
Shepherdin (79-87) is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity .

HY-P1750A

Shepherdin (79-87) (TFA)	HSP Survivin	Cancer
Shepherdin (79-87) TFA is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity .

HY-N1988

Cucurbitacin IIa Hemslecin A	Survivin Apoptosis	Cancer
Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of *survivin*, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells .

HY-137843

NSC 80467	DNA/RNA Synthesis	Cancer
NSC 80467, a DNA damaging agent, selectively inhibits survivin. NSC 80467 preferentially inhibits DNA synthesis and results in induction of γH2AX and pKAP1, two markers of DNA damage .

HY-160438B

PBX-7011 TFA	Others	Cancer
PBX-7011 TFA is a derivative of camptothecin (HY-16560), which inhibits expressions of the cancer related survival genes DDX5, Survivin, Mcl-1 and XIAP in cells FaDu, degrades DDX5 proteins and exhibits anticancer activity .

HY-112799

DK419	Wnt β-catenin	Cancer
DK419 is a potent and orally active Wnt/β-catenin signaling inhibitor, with an IC₅₀ of 0.19 μM. DK419 reduces protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK .

HY-162148

HNPMI	EGFR	Cancer
HNPMI is an inhibitor of EGFR and has cytotoxic effects on tumor cells. HNPMI can downregulate the protein levels of osteopontin, survivin and cathepsin S, leading to apoptosis. HNPMI also regulates BCL-2/BAX and p53 in CRC cell lines to inhibit tumorigenesis .

HY-162324

MX106-4C	Survivin	Cancer
MX106-4C is a survivin inhibitor that selectively kills ABCB1-positive colorectal cancer cells. MX106-4C can exert synergistic anticancer effects with Doxorubicin or resensitize drug-resistant ABCB1 cells to Doxorubicin .

HY-12486

FL118 10,11-(Methylenedioxy)-20(S)-camptothecin	Survivin Apoptosis IAP	Cancer
FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin (HY-16560) analogue, is a potent and orally active *survivin* inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer .

HY-136658

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea 1 Publications Verification	STAT Apoptosis	Cancer
STAT3-IN-7 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-7 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-7 does not inhibit kinase activity and has anticancer effects .

HY-15191

Sabutoclax BI-97C1	Bcl-2 Family	Cancer
Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC₅₀s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively. Sabutoclax increases Bax, Bim, PUMA and survivin expression .

HY-12830

M-110	Pim	Cancer
M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC₅₀=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC₅₀s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC₅₀s of 0.6 to 0.9 μM .

HY-13425

Deguelin 5 Publications Verification (-)-Deguelin; (-)-cis-Deguelin	Akt Autophagy Apoptosis	Cancer
Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.

HY-N6064

Polygalacin D 1 Publications Verification	Apoptosis IAP	Cancer
Polygalacin D (PGD) is a bioactive compound isolated from Platycodon grandiflorum with anticancer and anti-proliferative properties. PGD suppresses the expression of the IAP family of proteins including survivin, cIAP-1 and cIAP-2 and blocks the PI3K/Akt pathway by inhibiting the phosphorylation of GSK3β, Akt and the expression of PI3K. Polygalacin D induces apoptosis

HY-N0060B

(E)-Ferulic acid (E)-Coniferic acid
(E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-N8146

Bruceantinol	STAT	Infection Cancer
Bruceantinol, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper . Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC₅₀=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc .

HY-W010995

2,5-Dimethylcelecoxib	Wnt Survivin β-catenin	Cancer
2,5-Dimethylcelecoxib is an analogue of celecoxib (HY-14398) with anticancer activity but without COX-2 inhibitory activity. 2,5-Dimethylcelecoxib exerts its anti-cancer cell proliferation effect by inhibiting the core mechanism of the Wnt/β-catenin signaling pathway. 2,5-Dimethylcelecoxib also inhibits T-cell factor-dependent transcriptional activity and inhibits expression of the Wnt/β-catenin target gene products cyclin D1 and survivin .

HY-12803

Fulvene-5	NADPH Oxidase Reactive Oxygen Species	Cancer
Fulvene-5 is a potent NADPH oxidase 4 (NOX4) inhibitor with antioxidant properties. Fulvene-5 is a reactive oxygen species (ROS) modifying agent and a potent radioprotector. Fulvene-5 has antitumor activity .

HY-N6682

Cytochalasin D Maximum Cited Publications 40 Publications Verification Zygosporin A; NSC 209835	Arp2/3 Complex Antibiotic YAP	Infection
Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap .

HY-149007

STAT3-IN-11 1 Publications Verification	STAT Apoptosis	Cancer
STAT3-IN-11 (7a) is a selective STAT3 inhibitor that inhibits the phosphorylation of STAT3 at site pTyr705. STAT3-IN-11 inhibits the phosphorylation of downstream genes (Survivin and Mcl-1) without affecting its upstream tyrosine kinases (Src and JAK2) levels and p-STAT1 expression. STAT3-IN-11 can induce cancer cell apoptosis, which is potential for the discovery of effective STAT3 inhibitors and antitumor agents against cancers .

HY-123931

ZLDI-8 1 Publications Verification	Notch Phosphatase Apoptosis	Cancer
ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition (EMT) related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase (Lyp) inhibitor with an IC₅₀ of 31.6 μM and a K_i of 26.22 μM. ZLDI-8 inhibits the growth of MHCC97-H cells with an IC₅₀ of 5.32 μM .

HY-N0060BS

(E)-Ferulic acid-d3 (E)-Coniferic acid-d₃	β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite	Cancer
(E)-Ferulic acid-d₃ is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].

HY-107738

Guggulsterone 5+ Cited Publications Z/E-Guggulsterone	Apoptosis JNK Akt Caspase FXR Autophagy	Cancer
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt . Guggulsterone, a farnesoid X receptor (FXR) antagonist, decreases CDCA-induced FXR activation with IC₅₀s of 17 and 15 μM for Z- and E-Guggulsterone, respectively .

HY-19831A

(Z)-4EGI-1	Eukaryotic Initiation Factor (eIF)	Cancer
(Z)-4EGI-1 is the Z-isomer of 4EGI-1 and is an inhibitor of eIF4E/eIF4G interaction and of translation initiation. (Z)-4EGI-1 effectively binds to eIF4E with an IC₅₀ of 43.5 μM and a K_d value of 8.74 μM. (Z)-4EGI-1 has anticancer activity .

Cat. No.	Product Name

HY-L003

Apoptosis Compound Library	2211 compounds
Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions, which is also called programmed cell death (PCD). Apoptosis plays a crucial role in developing and maintaining the health of the body by eliminating old cells, unhealthy cells and unnecessary cells. Too little or too much apoptosis contribute to many diseases. When apoptosis does not work correctly, cells that should be eliminated may persist and become immortal, for example, in cancer and leukemia. When apoptosis works overly well, it kills too many cells and inflicts grave tissue damage. This is the case in strokes and neurodegenerative disorders such as Alzheimer's, Huntington's, and Parkinson's disease. MCE designs a unique collection of 2211 apoptosis-related compounds mainly focusing on the key targets in the apoptosis signaling pathway and can be used in the research of apoptosis signal pathway and related diseases.

Apoptosis Compound Library

2211 compounds

Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions, which is also called programmed cell death (PCD). Apoptosis plays a crucial role in developing and maintaining the health of the body by eliminating old cells, unhealthy cells and unnecessary cells. Too little or too much apoptosis contribute to many diseases. When apoptosis does not work correctly, cells that should be eliminated may persist and become immortal, for example, in cancer and leukemia. When apoptosis works overly well, it kills too many cells and inflicts grave tissue damage. This is the case in strokes and neurodegenerative disorders such as Alzheimer's, Huntington's, and Parkinson's disease.

MCE designs a unique collection of 2211 apoptosis-related compounds mainly focusing on the key targets in the apoptosis signaling pathway and can be used in the research of apoptosis signal pathway and related diseases.

Cat. No.	Product Name	Target	Research Area

HY-P1750A

Shepherdin (79-87) (TFA)	HSP Survivin	Cancer
Shepherdin (79-87) TFA is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity .

HY-P1750

Shepherdin (79-87)	HSP Survivin	Cancer
Shepherdin (79-87) is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1988

Cucurbitacin IIa Hemslecin A	Triterpenes Classification of Application Fields Terpenoids Source classification Cucurbitaceae Plants Hemsleya chinensis Cogn. ex Forbes et Hemsl. Disease Research Fields Cancer	Survivin Apoptosis
Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of *survivin*, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells .

HY-13425

Deguelin 5 Publications Verification (-)-Deguelin; (-)-cis-Deguelin	Structural Classification Flavonoids Classification of Application Fields Leguminosae Isoflavanones Source classification Derris trifoliata Lour. Plants Disease Research Fields Biological Pesticide Research Cancer Agricultural Research	Akt Autophagy Apoptosis
Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.

HY-N6064

Polygalacin D 1 Publications Verification	Triterpenes Classification of Application Fields Terpenoids Source classification Platycodon grandiflorus (Jacq.) A. DC. Campanulaceae Plants Disease Research Fields Cancer	Apoptosis IAP
Polygalacin D (PGD) is a bioactive compound isolated from Platycodon grandiflorum with anticancer and anti-proliferative properties. PGD suppresses the expression of the IAP family of proteins including survivin, cIAP-1 and cIAP-2 and blocks the PI3K/Akt pathway by inhibiting the phosphorylation of GSK3β, Akt and the expression of PI3K. Polygalacin D induces apoptosis

HY-N8146

Bruceantinol	Infection Triterpenes Simaroubaceae Classification of Application Fields Brucea antidysenterica J.F.Mill. Terpenoids Source classification Plants Disease Research Fields Cancer Brucea javanica (L.) Merr.	STAT
Bruceantinol, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper . Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC₅₀=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc .

HY-N6682

Cytochalasin D Maximum Cited Publications 40 Publications Verification Zygosporin A; NSC 209835	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Arp2/3 Complex Antibiotic YAP
Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap .

HY-107738

Guggulsterone 5+ Cited Publications Z/E-Guggulsterone	Triterpenes Structural Classification Classification of Application Fields Terpenoids Plants Burseraceae Disease Research Fields Commiphora wightii Cancer	Apoptosis JNK Akt Caspase FXR Autophagy
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt . Guggulsterone, a farnesoid X receptor (FXR) antagonist, decreases CDCA-induced FXR activation with IC₅₀s of 17 and 15 μM for Z- and E-Guggulsterone, respectively .

Species:	Human (8) Mouse (1)
Tag:	SUMO (1) His (8) Tag Free (1) Avi (6)
Source:	HEK293 (6) P. pastoris (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P7645

	BIRC5 Protein, Human rHuBIRC5; Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor 4; BIRC5; survivin; BIRC5	Human	E. coli
	BIRC5 Protein, Human, a protein in the intrinsic apoptotic pathway that interacts with XIAP and DIABLO leading to caspase-3 and caspase-9 inactivation. BIRC5 (survivin) is also involved in stabilizing the microtubule-kinetochore dynamics.

HY-P702495

	BIRC5 Protein, Human (His-SUMO) rHuBIRC5; Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor 4; BIRC5; survivin; BIRC5	Human	E. coli
	The BIRC5 protein has dual roles in cell proliferation and prevention of apoptosis. It is an important CPC component and guides chromosome alignment and segregation during mitosis. It directs CPC movement, contributes to central spindle organization, and recruits CPC to centromeres. BIRC5 Protein, Human (His-SUMO) is the recombinant human-derived BIRC5 protein, expressed by E. coli , with labeled tag. The total length of BIRC5 Protein, Human (His-SUMO) is 142 a.a., with molecular weight of 32.5 kDa.

HY-P700944

	*HLA-A0201 Survivin Complex Protein, Human (Biotinylated, LMLGEFLKL, HEK293, His-Avi)** survivin; MHC; MHC I; BIRC5; API4; EPR-1; IAP4; survivin variant 3 alpha	Human	HEK293
	HLA-A0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A0201 Survivin Complex Protein, Human (Biotinylated, LMLGEFLKL, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A0201 Survivin Complex protein, expressed by HEK293, with C-Avi, C-His labeled tag. HLA-A*0201 Survivin Complex Protein, Human (Biotinylated, LMLGEFLKL, HEK293, His-Avi), has molecular weight of 55-63 kDa.

HY-P77770

	*HLA-A0201 Survivin Complex Tetramer Protein, Human (HEK293, His-Avi)** survivin; MHC; MHC I; BIRC5; API4; EPR-1; IAP4; survivin variant 3 alpha	Human	HEK293
	HLA-A0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A0201 Survivin Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A0201 Survivin Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 Survivin Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.

HY-P77769

	*HLA-A0201 Survivin Complex Protein, Human (HEK293, His-Avi)** survivin; MHC; MHC I; BIRC5; API4; EPR-1; IAP4; survivin variant 3 alpha	Human	HEK293
	HLA-A0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A0201 Survivin Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A0201 Survivin Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 Survivin Complex Protein, Human (HEK293, His-Avi), has molecular weight of 53-60 kDa.

HY-P700946

HLA-A*2402 Survivin 2B Complex Protein, Human (AYACNTSTL, HEK293, His-Avi)

svn-2B; survivin-2B; svn 2B
Human HEK293
HY-P700945

HLA-A*2402 Survivin 2B Complex Protein, Human (Biotinylated, AYACNTSTL, HEK293, His-Avi)

svn-2B; survivin-2B; svn 2B
Human HEK293
HY-P700947

HLA-A*2402 Survivin 2B Complex Tetramer Protein, Human (AYACNTSTL, HEK293, His-Avi)

svn-2B; survivin-2B; svn 2B
Human HEK293

HY-P71717

	Apoptosis inhibitor 4/Birc5 Protein, Mouse (P.pastoris, His) Birc5; Api4; Iap4Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin; TIAP	Mouse	P. pastoris
	Apoptosis inhibitor 4/Birc5 has the dual effects of promoting cell proliferation and inhibiting apoptosis. As an important component of the chromosomal channel protein complex (CPC), Birc5 coordinates chromosome alignment and segregation during mitosis and cytokinesis. Apoptosis inhibitor 4/Birc5 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Apoptosis inhibitor 4/Birc5 protein, expressed by P. pastoris , with N-His labeled tag. The total length of Apoptosis inhibitor 4/Birc5 Protein, Mouse (P.pastoris, His) is 140 a.a., with molecular weight of ~18.3 kDa.

Cat. No.	Product Name	Chemical Structure

HY-N0060BS

(E)-Ferulic acid-d3

(E)-Ferulic acid-d₃ is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].

Cat. No.	Product Name	Application	Reactivity

HY-P80352

Survivin Antibody (YA045)	WB, ICC/IF, IHC-P, FC	Human, Mouse
Survivin Antibody (YA045) is a non-conjugated and Rabbit origined monoclonal antibody about 16 kDa, targeting to Survivin. It can be used for WB,ICC/IF,IHC-P,FC assays with tag free, in the background of Human, Mouse.

HY-P80906

Survivin Antibody (YA665) BIRC5; API4; IAP4; Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin	WB, IHC-P	Human, Rat
Survivin Antibody (YA665) is a non-conjugated and Mouse origined monoclonal antibody about 16 kDa, targeting to Survivin (8B9). It can be used for WB,IHC-P assays with tag free, in the background of Human, Rat.


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