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Results for "

tetracyclic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (3) ADC Cytotoxin (1) Adrenergic Receptor (2) Akt (1) Antibiotic (4) Apoptosis (1) Autophagy (5) Bacterial (3) COX (2) Endogenous Metabolite (2) Histamine Receptor (4) HIV (2) Integrin (1) Isotope-Labeled Compounds (3) MAGL (1) NF-κB (1) Parasite (1) Phospholipase (2) ROS Kinase (1) Somatostatin Receptor (1)
By Research Areas:	Cancer (8) Endocrinology (3) Infection (5) Inflammation/Immunology (6) Neurological Disease (20)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N8137

Cucurbitacin Q1

Others Others

Cucurbitacin Q1 is a tetracyclic triterpene that can be found in Cucumis prophetarum .

Cucurbitacin Q1	Others	Others
Cucurbitacin Q1 is a tetracyclic triterpene that can be found in Cucumis prophetarum .

HY-32329A

Setiptiline maleate MO-8282	5-HT Receptor	Neurological Disease
Setiptiline maleate (MO-8282 maleate) is a serotonin receptor antagonist. Setiptiline maleate is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline maleate acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT_2A, 5-HT_2C, and/or 5-HT₃ subtypes, as well as an H1 receptor inverse agonist/antihistamine .

HY-N2556

Tirucallol	Others	Inflammation/Immunology
Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages .

HY-113818

Kadsuracoccinic acid A	HIV	Infection
Kadsuracoccinic acid A is a tetracyclic natural compound that can be isolated from the stems of Kadsura coccinea. Kadsuracoccinic acid A has vitro anti-HIV-1 activitiy with an EC₅₀ value of 68.7 μM .

HY-137309

4-Deoxy-4α-phorbol	HIV	Others
4-Deoxy-4α-phorbol is a tetracyclic diterpene found in E. desmondi. It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters .

HY-N0901

Corynoxine	Autophagy	Neurological Disease Cancer
Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .

HY-N0901B

Corynoxine hydrochloride	Autophagy	Neurological Disease Cancer
Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .

HY-125664

Lucialdehyde B	Antibiotic	Cancer
Lucialdehyde B is a tetracyclic triterpene isolated from the substrates of Ganoderma lucidum with antiviral and cytotoxic activities. Lucialdehyde B has cytotoxic effects against Lewis lung cancer (LLC), T-47D, Sarcoma 180 and Meth-A tumor cell lines .

HY-142774

Lp-PLA2-IN-6	Phospholipase	Neurological Disease
Lp-PLA2-IN-6 (compound 18), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC₅₀ of 10.0 for rhLp-PLA2. Lp-PLA2-IN-6 has the potential for neurodegenerative related diseases research .

HY-142777

Lp-PLA2-IN-9	Phospholipase	Neurological Disease
Lp-PLA2-IN-9 (compound 17), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC₅₀ of 10.1 for rhLp-PLA2. Lp-PLA2-IN-9 has the potential for neurodegenerative related diseases research .

HY-106338

Polyketomycin	Bacterial ADC Cytotoxin Parasite	Infection Cancer
Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 µg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities .

HY-B0444

Maprotiline hydrochloride 1 Publications Verification	Autophagy	Neurological Disease
Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.

HY-B0188

Mianserin

Mianserine
Histamine Receptor Neurological Disease Endocrinology

Mianserin is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.
HY-19081

KB-5246

Bacterial Antibiotic Infection

KB-5246 is a tetracyclic quinolone and displays antibacterial activities.

Mianserin Mianserine	Histamine Receptor	Neurological Disease Endocrinology
Mianserin is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.

KB-5246	Bacterial Antibiotic	Infection
KB-5246 is a tetracyclic quinolone and displays antibacterial activities.

HY-122300

R-(-)-Oxaprotiline hydrochloride Levoprotiline hydrochloride	Others	Neurological Disease
R-(-)-Oxaprotiline (Levoprotiline) hydrochloride is the R-enantiomer of Oxaprotiline. Oxaprotiline is a tetracyclic antidepressant agent .

HY-133194

Taxinine M

Others Others

Taxinine M, a tetracyclic taxane, can be isolated from Taxus brevifolia .
HY-N1542

Prionitin

Prionitin is a tetracyclic diterpene that can be isolated from the roots of S. prionitis Hance .

Taxinine M	Others	Others
Taxinine M, a tetracyclic taxane, can be isolated from Taxus brevifolia .

Prionitin
Prionitin is a tetracyclic diterpene that can be isolated from the roots of S. prionitis Hance .

HY-B0991

Amoxapine 2 Publications Verification CL-67772	Others	Neurological Disease
Amoxapine is a tetracyclic antidepressant of the dibenzoxazepine family, although it is generally classified as a secondary amine tricyclic antidepressant.

HY-N1281

Sendanolactone

Others Others

Sendanolactone is a new tetracyclic triterpenoid from the bark of M. azedarach L. var. japonica Makino .
HY-P1695

Cinnamycin

Ro 09-0198
Antibiotic Bacterial Infection

Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .

Sendanolactone	Others	Others
Sendanolactone is a new tetracyclic triterpenoid from the bark of M. azedarach L. var. japonica Makino .

Cinnamycin Ro 09-0198	Antibiotic Bacterial	Infection
Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .

HY-B0188A

Mianserin hydrochloride Org GB 94	Histamine Receptor	Neurological Disease Endocrinology
Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.

HY-N3924

Ganoderiol F

Others Others

Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines .

Ganoderiol F	Others	Others
Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines .

HY-N9737

(−)-Acutumine	Others	Neurological Disease
(−)-Acutumine is a tetracyclic chloroalkaloid that exhibits selective cytotoxicity to cultured human T cells and memory-enhancing properties in the Wistar rat model .

HY-B0444S

Maprotiline-d5 hydrochloride	Autophagy	Neurological Disease
Maprotiline-d₅ (hydrochloride) is the deuterium labeled Maprotiline hydrochloride. Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant[1][2].

HY-B0991S

Amoxapine-d8 CL-67772-d₈	Isotope-Labeled Compounds	Neurological Disease
Amoxapine-d₈ is the deuterium labeled Amoxapine. Amoxapine is a tetracyclic antidepressant of the dibenzoxazepine family, though it is often classified as a secondary amine tricyclic antidepressant.

HY-B0188AS

Mianserin-d3 hydrochloride Org GB 94-d₃	Histamine Receptor	Neurological Disease Endocrinology
Mianserin-d₃ (hydrochloride) is the deuterium labeled Mianserin hydrochloride. Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.

HY-B0188S

Mianserin-d3 Mianserine-d₃	Histamine Receptor Isotope-Labeled Compounds	Neurological Disease
Mianserin-d3 is the deuterium labeled Mianserin (HY-B0188). Mianserin? is a Histamine 1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant .

HY-B0991R

Amoxapine (Standard) CL-67772 (Standard)	Others	Neurological Disease
Amoxapine (Standard) is the analytical standard of Amoxapine. This product is intended for research and analytical applications. Amoxapine is a tetracyclic antidepressant of the dibenzoxazepine family, although it is generally classified as a secondary amine tricyclic antidepressant.

HY-N0481

Roburic acid	COX	Inflammation/Immunology
Roburic acid, a tetracyclic triterpenoid found in Gentiana macrophylla, acts as an inhibitor of COX, with IC₅₀s of 5 and 9 μM for COX-1 and COX-2, respectively .

HY-N3188

Niloticin	Akt NF-κB	Infection
Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways .

HY-N6252

Gypenoside XLVI	Others	Cancer
Gypenoside XLVI is one of the major dammarane-type triterpenoid saponins from Gynostamma pentaphallum . Gypenoside XLVI has a tetracyclic triterpene structure and possess potent non-small cell lung carcinoma A549 cell inhibitory activity .

HY-N0829

Shionone	Others	Inflammation/Immunology
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-156843

Antiproliferative agent-38	Others	Cancer
Antiproliferative agent-38 (com 18) is a tetracyclic ring, but its most reactive ring nitrogen (probably the quinoline moiety) cannot undergo N-alkylation. Antiproliferative agent-38 lacks anti-malarial activity and lacks anti-cancer cell proliferation activity .

HY-N0416

Cucurbitacin B Maximum Cited Publications 7 Publications Verification	Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX	Others Neurological Disease Inflammation/Immunology Cancer
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-N0313

Euphol	MAGL Endogenous Metabolite	Inflammation/Immunology
Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC₅₀=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .

HY-N1511

Ganoderic acid D 1 Publications Verification
Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .

HY-P10027

Clovibactin	Antibiotic	Inflammation/Immunology
Clovibactin is a new antibiotic. Clovibactin efficiently kills drug-resistant bacterial pathogens without detectable resistance. Clovibactin can be isolated from uncultured soil bacteria .

HY-32329

Setiptiline Org-8282	5-HT Receptor Adrenergic Receptor	Neurological Disease
Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.

HY-P1206

CH 275	Somatostatin Receptor	Neurological Disease
CH 275 is a peptide analog of somatostatin and binds preferably to somatostatin receptor 1 (sst₁) with a K_i of 52 nM . CH 275 acts as a potent and selective sst₁ agonist (IC₅₀=30.9 nM) and also displays IC₅₀ values of 345 nM, >1 μM, >10 μM, >10 μM for human sst₃, sst₄, sst₂ and sst₅, respectively . CH 275 can be used for the research of alzheimer’s disease .

HY-32329S

Setiptiline-d3	Isotope-Labeled Compounds 5-HT Receptor Adrenergic Receptor	Neurological Disease
Setiptiline-d₃ is the deuterium labeled Setiptiline. Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine[1][2].

CH 275	Somatostatin Receptor	Neurological Disease
CH 275 is a peptide analog of somatostatin and binds preferably to somatostatin receptor 1 (sst₁) with a K_i of 52 nM . CH 275 acts as a potent and selective sst₁ agonist (IC₅₀=30.9 nM) and also displays IC₅₀ values of 345 nM, >1 μM, >10 μM, >10 μM for human sst₃, sst₄, sst₂ and sst₅, respectively . CH 275 can be used for the research of alzheimer’s disease .

Cyclic nona-L-arginine hydrochloride	Peptides	Others
Cyclic nona-L-arginine hydrochloride, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .

Cyclic nona-L-arginine TFA	Peptides	Others
Cyclic nona-L-arginine TFA, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .

Cyclic PSAP peptide	Peptides	Cancer
Cyclic PSAP peptide is a cyclic pentapeptide (DWLPK). Cyclic PSAP peptide exhibits agent-like properties and could inhibit metastatic spread and restrain tumor development in general in vivo .

Clovibactin	Antibiotic	Inflammation/Immunology
Clovibactin is a new antibiotic. Clovibactin efficiently kills drug-resistant bacterial pathogens without detectable resistance. Clovibactin can be isolated from uncultured soil bacteria .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8137

Cucurbitacin Q1	Triterpenes other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Others
Cucurbitacin Q1 is a tetracyclic triterpene that can be found in Cucumis prophetarum .

HY-N2556

Tirucallol	Triterpenes Classification of Application Fields Euphorbia boetica Terpenoids Source classification Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology	Others
Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages .

HY-N0901

Corynoxine	Uncaria rhynchophylla (Miq.) Miq. ex Havil. Alkaloids Source classification Rubiaceae Plants Indole Alkaloids	Autophagy
Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .

HY-113818

Kadsuracoccinic acid A	Structural Classification Natural Products Source classification Plants Kadsura coccinea (Lem.) A. C. Smith Schisandraceae	HIV
Kadsuracoccinic acid A is a tetracyclic natural compound that can be isolated from the stems of Kadsura coccinea. Kadsuracoccinic acid A has vitro anti-HIV-1 activitiy with an EC₅₀ value of 68.7 μM .

HY-137309

4-Deoxy-4α-phorbol	Structural Classification Terpenoids Source classification Euphorbia cooperi N. E. Br. ex A. Berger Diterpenoids Euphorbiaceae Plants	HIV
4-Deoxy-4α-phorbol is a tetracyclic diterpene found in E. desmondi. It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters .

HY-N0901B

Corynoxine hydrochloride	Uncaria rhynchophylla (Miq.) Miq. ex Havil. Alkaloids Source classification Rubiaceae Plants Indole Alkaloids	Autophagy
Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .

HY-125664

Lucialdehyde B	Triterpenes Structural Classification Microorganisms Classification of Application Fields Terpenoids Disease Research Fields Cancer	Antibiotic
Lucialdehyde B is a tetracyclic triterpene isolated from the substrates of Ganoderma lucidum with antiviral and cytotoxic activities. Lucialdehyde B has cytotoxic effects against Lewis lung cancer (LLC), T-47D, Sarcoma 180 and Meth-A tumor cell lines .

HY-106338

Polyketomycin	Infection Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Naphthalene Quinones Disease Research Fields	Bacterial ADC Cytotoxin Parasite
Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 µg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities .

HY-133194

Taxinine M	Structural Classification Natural Products Taxus cuspidata Siebold & Zucc. Source classification Taxaceae Plants	Others
Taxinine M, a tetracyclic taxane, can be isolated from Taxus brevifolia .

HY-N1281

Sendanolactone	Triterpenes Structural Classification Melia azedarach Linn. Terpenoids Source classification Plants Meliaceae	Others
Sendanolactone is a new tetracyclic triterpenoid from the bark of M. azedarach L. var. japonica Makino .

HY-B0188A

Mianserin hydrochloride Org GB 94	Alkaloids Structural Classification Neurological Disease Classification of Application Fields Leguminosae Source classification Plants Crotalaria pallida Ait. Disease Research Fields Endocrinology	Histamine Receptor
Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.

HY-N3924

Ganoderiol F	Triterpenes Microorganisms Terpenoids Source classification	Others
Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines .

HY-N9737

(−)-Acutumine	Structural Classification Alkaloids Pyrrole Alkaloids Source classification Plants Menispermaceae	Others
(−)-Acutumine is a tetracyclic chloroalkaloid that exhibits selective cytotoxicity to cultured human T cells and memory-enhancing properties in the Wistar rat model .

HY-N0481

Roburic acid	Triterpenes Gentiana macrophylla Pall. Classification of Application Fields Terpenoids Source classification Gentianaceae Plants Disease Research Fields Inflammation/Immunology	COX
Roburic acid, a tetracyclic triterpenoid found in Gentiana macrophylla, acts as an inhibitor of COX, with IC₅₀s of 5 and 9 μM for COX-1 and COX-2, respectively .

HY-N3188

Niloticin	Infection Triterpenes Structural Classification Phellodendron chinense Schneid. Classification of Application Fields Terpenoids Source classification Rutaceae Plants Disease Research Fields	Akt NF-κB
Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways .

HY-N6252

Gypenoside XLVI	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Cucurbitaceae Plants Disease Research Fields Gynostemma pentaphyllum (Thunb.) Makino Cancer	Others
Gypenoside XLVI is one of the major dammarane-type triterpenoid saponins from Gynostamma pentaphallum . Gypenoside XLVI has a tetracyclic triterpene structure and possess potent non-small cell lung carcinoma A549 cell inhibitory activity .

HY-N0829

Shionone	Structural Classification Classification of Application Fields Terpenoids Diterpenoids Plants Compositae Inflammation/Immunology Disease Research Fields Sesbania vesicaria (Jacq.) Elliott	Others
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .

HY-N0416

Cucurbitacin B 5+ Cited Publications	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Cucurbitaceae Trichosanthes cucumerina L. Plants Endogenous metabolite Disease Research Fields Cancer	Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-N0313

Euphol	Triterpenes Structural Classification Classification of Application Fields Terpenoids Euphorbiaceae Plants Inflammation/Immunology Disease Research Fields	MAGL Endogenous Metabolite
Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC₅₀=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .

Cat. No.	Product Name	Chemical Structure

HY-B0444S

Maprotiline-d5 hydrochloride
Maprotiline-d₅ (hydrochloride) is the deuterium labeled Maprotiline hydrochloride. Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant[1][2].

HY-B0991S

Amoxapine-d8
Amoxapine-d₈ is the deuterium labeled Amoxapine. Amoxapine is a tetracyclic antidepressant of the dibenzoxazepine family, though it is often classified as a secondary amine tricyclic antidepressant.

HY-B0188AS

Mianserin-d3 hydrochloride
Mianserin-d₃ (hydrochloride) is the deuterium labeled Mianserin hydrochloride. Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.

HY-B0188S

Mianserin-d3
Mianserin-d3 is the deuterium labeled Mianserin (HY-B0188). Mianserin? is a Histamine 1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant .

HY-32329S

Setiptiline-d3

Setiptiline-d₃ is the deuterium labeled Setiptiline. Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine[1][2].

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tetracyclic

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
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