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Results for "

transfection

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Bacterial (2) Biochemical Assay Reagents (3) c-Kit (1) DNA/RNA Synthesis (2) Endogenous Metabolite (1) Fluorescent Dye (2) Liposome (20) PROTAC Linkers (1) RET (7) VEGFR (1)
By Research Areas:	Cancer (9) Infection (4) Inflammation/Immunology (2) Metabolic Disease (2)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

MCE Kits

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112301A

trans-Pralsetinib trans-BLU-667	RET	Cancer
trans-Pralsetinib (trans-BLU-667) is a *rearranged during transfection* (RET)** inhibitor extracted from patent US20170121312A1, Compound Example 129 .

HY-112754A

DOTAP chloride 2 Publications Verification 1,2-Dioleoyl-3-trimethylammonium-propane chloride	Liposome	Cancer
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .

HY-139200

DOTMA	Liposome	Others
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .

HY-W800783

DSTAP chloride CDESA	Liposome	Others
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .

HY-142997

DOSPA

Liposome Others

DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .

DOSPA	Liposome	Others
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .

HY-144015

14:1 EPC trifluoromethanesulfonate	Liposome	Others
14:1 EPC trifluoromethanesulfonate is ethyl-phosphatidylcholine (EPC) with monounsaturated 14:1 chains. 14:1 EPC trifluoromethanesulfonate shows transfection activity. 14:1 EPC trifluoromethanesulfonate can be used for drug delivery .

HY-149037

GL67 N4-Spermine cholesteryl carbamate	Liposome	Others
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-112005

DOPE dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	Liposome Endogenous Metabolite	Inflammation/Immunology
DOPE (dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-149037A

GL67 pentahydrochloride N4-Spermine cholesteryl carbamate pentahydrochloride	Liposome	Others
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-P0311

LAH4	Bacterial	Infection
LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .

HY-P0311A

LAH4 TFA	Bacterial	Infection
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .

HY-W250110

Polyethylenimine (branched) 2 Publications Verification	Biochemical Assay Reagents	Infection Others
Polyethylenimine (PEI) branched is a organic macromolecule with high cationic-charge-density potential. PEI can ensnare DNA as well as attach to cell membrane, PEI also retains a substantial buffering capacity at virtually any pH. PEI is widely used as transfection reagent .

HY-153082

Firefly Luciferase circRNA	Fluorescent Dye	Others
Firefly Luciferase circRNA will express a luciferase protein, originally isolated from the Photinus pyralis (Firefly). Firefly Luciferase circRNA is ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.

HY-W590549

Dioleyldimethylammonium chloride

DODAC
Others Others

Dioleyldimethylammonium chloride (DODAC) is a cationic lipid that can be used as transfection reagent .

Dioleyldimethylammonium chloride DODAC	Others	Others
Dioleyldimethylammonium chloride (DODAC) is a cationic lipid that can be used as transfection reagent .

HY-W127378

DOTAP methylsulfate 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate	Biochemical Assay Reagents	Others
DOTAP Transfection Reagent is a cationic derivative of trimethylammonium attached to two 18-carbon fatty acid tails, each with a single alkene group. 18:1 TAP is a cationic liposome-forming compound useful for the transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.

HY-144022

16:0 DAP

Biochemical Assay Reagents Others

16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .

16:0 DAP	Biochemical Assay Reagents	Others
16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .

HY-153081

eGFP circRNA	Fluorescent Dye	Others
The eGFP circRNA will express green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. The eGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence with an emission peak at 509 nm. The eGFP circRNA is therefore ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.

HY-34595

Pyrazoloadenine

RET Cancer

Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity .

Pyrazoloadenine	RET	Cancer
Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity .

HY-W800776

DORI 1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide	Liposome	Others
DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .

HY-145024

RET-IN-6

RET Cancer

RET-IN-6 is a potent RET (rearranged during transfection) inhibitor with an IC₅₀ of 4.57 nM (CN113461670A, compound 321) .
HY-125529

DMPAC-Chol

Chol-T
Liposome Others

DMPAC-Chol (Chol-T) is used for liposome formation. DMPAC-Chol (Chol-T) liposomes exhibits great transfection effciencies .
HY-148842

C14-4

Liposome Others

C14-4 is an ionizable lipid for lipid nanoparticles (LNPs) formulation. C14-4 was identified for its potent transfection and low cytotoxicity.

RET-IN-6	RET	Cancer
RET-IN-6 is a potent RET (rearranged during transfection) inhibitor with an IC₅₀ of 4.57 nM (CN113461670A, compound 321) .

DMPAC-Chol Chol-T	Liposome	Others
DMPAC-Chol (Chol-T) is used for liposome formation. DMPAC-Chol (Chol-T) liposomes exhibits great transfection effciencies .

C14-4	Liposome	Others
C14-4 is an ionizable lipid for lipid nanoparticles (LNPs) formulation. C14-4 was identified for its potent transfection and low cytotoxicity.

HY-W590680

ssPalmM	Liposome	Others
ssPalmM is a SS-cleavable proton-activated lipid-like materials. ssPalmM can be used to form lipid nanoparticles (LNPs) for nuclear targeting of plasmid DNA .

HY-151862

3-Azidopropylamine	ADC Linker	Others
3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA .

HY-144422

RET-IN-15	RET	Cancer
RET-IN-15 is a *rearranged during transfection* (RET) kinase** inhibitor extracted from patent WO2021115457A1 compound 51. RET-IN-15 can be used for the research of cancer .

HY-125734

DMHAPC-Chol	Liposome	Others
DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .

HY-145023

RET-IN-5	RET	Cancer
RET-IN-5 is a potent RET (rearranged during transfection) inhibitor with an IC₅₀s of 0.4 nM and 135.1 nM for RET and VEGFR2, respectively (WO2021213476A1, compound 18) .

HY-144016

16:0 EPC chloride	Liposome	Others
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .

HY-W590676

Tetramyristoylcardiolipin TMCL	Liposome	Others
Tetramyristoylcardiolipin (TMCL) is an anionic lipid. Tetramyristoylcardiolipin can be used to study cell membrane function and drug delivery .

HY-143545

RET-IN-8	RET	Cancer
RET-IN-8 is a *rearranged during transfection* (RET) kinase** inhibitor extracted from patent WO2021093720A1 compound I-1. RET-IN-8 can be used for the research of cancer .

HY-156936

RCB-02-4-8	Liposome	Others
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .

HY-148859

AA-T3A-C12	Liposome	Metabolic Disease Inflammation/Immunology
AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .

HY-W440827

DOPE-PEG-COOH (MW 2000) 1 Publications Verification	PROTAC Linkers	Cancer
DOPE-PEG-COOH (MW 2000) is a PEG-based PROTAC linker. DOPE-PEG-COOH (MW 2000) can be used in the synthesis of PROTACs. DOPE-PEG-COOH (MW 2000) can be used for drug delivery, gene transfection and vaccine delivery .

HY-W598178

93-O17O

Liposome Others

93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .

93-O17O	Liposome	Others
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .

HY-134541

SM-102 Maximum Cited Publications 7 Publications Verification	Liposome	Infection
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-112764

DMG-PEG 2000 4 Publications Verification	Liposome	Metabolic Disease
DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .

HY-145973

3'Ome-m7GpppAmpG	DNA/RNA Synthesis	Others
3'Ome-m7GpppAmpG is a trinucleotide Cap analogue containing a locked nucleic acid (LNA) molecule. 3'Ome-m7GpppAmpG shows a significant translational efficiency. 3'Ome-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .

HY-145973A

3'Ome-m7GpppAmpG ammonium	DNA/RNA Synthesis	Others
3'Ome-m7GpppAmpG ammonium is a trinucleotide Cap analogue containing a locked nucleic acid (LNA) molecule. 3'Ome-m7GpppAmpG ammonium shows a significant translational efficiency. 3'Ome-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .

HY-116116

Tafetinib SIM010603	c-Kit RET VEGFR	Cancer
Tafetinib (SIM010603) is an oral multi-targets receptor tyrosine kinases inhibitor. Tafetinib inhibitsstem cell factor receptor (Kit),vascular endothelial growth factor receptor-2 (VEGFR-2),platelet-derived growth factor receptor-β (PDGFR-β),*glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET)*, andFms-like tyrosine kinase-3 (FLT3)withIC₅₀values between 5.0 and 68.1 nmol/l. Tafetinib inhibits the phosphorylation ofPDGFR-βandVEGFR-2. Tafetinib inhibits endothelial cell proliferation, endothelial cells chemotaxis, and corneal angiogenesis .

Cat. No.	Product Name	Type

HY-112754A

DOTAP chloride 2 Publications Verification 1,2-Dioleoyl-3-trimethylammonium-propane chloride	Drug Delivery
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .

HY-139200

DOTMA	Drug Delivery
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .

DOTMA

Drug Delivery

DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .

HY-142997

DOSPA

Drug Delivery

DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .

DOSPA	Drug Delivery
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .