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trihydrate

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34

Inhibitors & Agonists

6

Biochemical Assay Reagents

3

Natural
Products

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16568

    (+)-Irinotecan hydrochloride trihydrate; CPT-11 hydrochloride trihydrate

    Topoisomerase Autophagy Cancer
    Irinotecan hydrochloride trihydrate ((+)-Irinotecan hydrochloride trihydrate) is a topoisomerase I inhibitor with antitumor activity .
    Irinotecan hydrochloride <em>trihydrate</em>
  • HY-101634A

    HCV Infection
    ABT-072 (potassium trihydrate) is an orally active and potent non-nucleoside HCV NS5B polymerase inhibitor (HCV GT1a EC50=1 nM; HCV GT1b EC50=0.3 nM) .
    ABT-072 potassium <em>trihydrate</em>
  • HY-B0639A
    Amifostine trihydrate
    5 Publications Verification

    WR2721 trihydrate

    MDM-2/p53 HIF/HIF Prolyl-Hydroxylase Cancer
    Amifostine trihydrate (WR2721 trihydrate) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine trihydrate selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine trihydrate is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine trihydrate protects cells from damage by scavenging oxygen-derived free radicals. Amifostine trihydrate reduces renal toxicity and has antiangiogenic action .
    Amifostine <em>trihydrate</em>
  • HY-Y1325E

    Sodium acetate trihydrate (Pharmaceutical primary standard, USP)

    Biochemical Assay Reagents Others
    Sodium acetate trihydrate, United States Pharmacopeia (USP) Reference Standard is an inorganic salt that can be used for life science related research .
    Sodium acetate <em>trihydrate</em>, United States Pharmacopeia (USP) Reference Standard
  • HY-17507E

    Proton Pump Bacterial Infection
    S-Pantoprazole (sodium trihydrate) is related to Pantoprazole (HY-17507) that plays an important roles in gastric acid secretion disorder-related diseases, or as proton pump inhibitor .
    S-Pantoprazole sodium <em>trihydrate</em>
  • HY-B1381A

    FR-17027 trihydrate; FK-027 trihydrate; CL-284635 trihydrate

    Antibiotic Bacterial Infection Inflammation/Immunology Cancer
    Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .
    Cefixime <em>trihydrate</em>
  • HY-17022

    (S)-Omeprazole magnesium trihydrate; (-)-Omeprazole magnesium trihydrate

    Proton Pump Endocrinology Cancer
    Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent and orally active H +, K +-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research . Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H +-ATPases .
    Esomeprazole magnesium <em>trihydrate</em>
  • HY-B0011A
    Docetaxel Trihydrate
    Maximum Cited Publications
    81 Publications Verification

    RP-56976 trihydrate

    Microtubule/Tubulin Apoptosis Cancer
    Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM . Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis .
    Docetaxel <em>Trihydrate</em>
  • HY-B2176A
    ATP disodium trihydrate
    50+ Cited Publications

    Adenosine-5'-triphosphate disodium trihydrate

    Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .
    ATP disodium <em>trihydrate</em>
  • HY-W013766

    Bacterial Antibiotic Infection
    Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections .
    Pipemidic acid <em>trihydrate</em>
  • HY-B0522B
    Ampicillin trihydrate
    30+ Cited Publications

    D-(-)-α-Aminobenzylpenicillin trihydrate

    Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
    Ampicillin <em>trihydrate</em>
  • HY-17015
    Peramivir trihydrate
    5+ Cited Publications

    RWJ 270201 trihydrate; BCX 1812 trihydrate

    Influenza Virus Infection
    Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes .
    Peramivir <em>trihydrate</em>
  • HY-B0343BS

    A-56620-d8 hydrochloride trihydrate

    Bacterial Inflammation/Immunology
    Sarafloxacin-d8 (hydrochloride trihydrate) is the deuterium labeled Sarafloxacin hydrochloride trihydrate. Sarafloxacin hydrochloride trihydrate is a quinolone antibiotic compound[1][2].
    Sarafloxacin-d8 hydrochloride <em>trihydrate</em>
  • HY-W013075
    Rutin trihydrate
    5+ Cited Publications

    Rutoside trihydrate; Quercetin 3-O-rutinoside trihydrate

    Apoptosis Endogenous Metabolite Neurological Disease Cancer
    Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities .
    Rutin <em>trihydrate</em>
  • HY-B0011AS

    RP-56976-d5 trihydrate

    Isotope-Labeled Compounds Microtubule/Tubulin Apoptosis Cancer
    Docetaxel-d5 (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis[1][3].
    Docetaxel-d5 <em>trihydrate</em>
  • HY-U00087

    Bacterial Infection
    Tosylchloramide sodium trihydrate (Chloramine T sodium trihydrate) is a disinfectant agent widely used in laboratories, kitchens and hospitals. It is also used as a biocide in air fresheners and deodorants.
    Tosylchloramide sodium <em>trihydrate</em>
  • HY-B1359
    Methylene blue trihydrate
    10+ Cited Publications

    C.I. Basic Blue 9 trihydrate

    Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue trihydrate is a vasopressor and is often used as a dye in several medical procedures. Methylene blue trihydrate has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue trihydrate has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment .
    Methylene blue <em>trihydrate</em>
  • HY-13678A
    Meropenem trihydrate
    10+ Cited Publications

    SM 7338 trihydrate

    Penicillin-binding protein (PBP) Bacterial Antibiotic Infection Cancer
    Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
    Meropenem <em>trihydrate</em>
  • HY-B0442B
    Vardenafil hydrochloride trihydrate
    1 Publications Verification

    Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride trihydrate shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4 . Vardenafil hydrochloride trihydrate competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels . Vardenafil hydrochloride trihydrate can be used for the research of erectile dysfunction, hepatitis, diabetes [1]-[6].
    Vardenafil hydrochloride <em>trihydrate</em>
  • HY-W094581

    Biochemical Assay Reagents Others
    Gold (III) chloride trihydrate is a reducing agent. Gold (III) chromium trihydrate can be used for chemical synthesis of gold nanoparticles (NP) and spirochromene derivatives .
    Gold(III) chloride <em>trihydrate</em>
  • HY-B0221A

    Antibiotic Fungal Bacterial Parasite Infection Inflammation/Immunology Cancer
    Amphotericin B trihydrate, a polyene antibiotic, is first isolated from fermenter cultures of Streptomyces nodosus. Amphotericin B trihydrate also possesses antileishmanial activity .
    Amphotericin B <em>trihydrate</em>
  • HY-B2155

    Acotiamide monohydrochloride trihydrate is an orally active, selective and reversible acetylcholinesterase (AChE) inhibitor, with IC50 of 1.79 μM. Acotiamide monohydrochloride trihydrate can enhance gastric contractility and accelerate delayed gastric emptying. Acotiamide monohydrochloride trihydrate has the potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory .
    Acotiamide monohydrochloride <em>trihydrate</em>
  • HY-14542B

    CP-88059 mesylate trihydrate

    5-HT Receptor Dopamine Receptor Neurological Disease
    Ziprasidone (CP-88059) mesylate trihydrate is an orally active combined 5-HT and dopamine receptor antagonist . Ziprasidone mesylate trihydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM) .
    Ziprasidone mesylate <em>trihydrate</em>
  • HY-13074
    VO-Ohpic trihydrate
    25+ Cited Publications

    PTEN Autophagy Cancer
    VO-Ohpic trihydrate is a highly potent inhibitor of PTEN with an IC50 of 46±10 nM.
    VO-Ohpic <em>trihydrate</em>
  • HY-122818
    bpV(phen) trihydrate
    2 Publications Verification

    PTEN Phosphatase Parasite Apoptosis Infection Metabolic Disease Inflammation/Immunology Cancer
    bpV(phen) trihydrate, a insulin-mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-β and PTP-1B, respectively. bpV(phen) trihydrate inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) trihydrate strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFNγ). bpV(phen) trihydrate can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity .
    bpV(phen) <em>trihydrate</em>
  • HY-B0589E

    HMG-CoA Reductase (HMGCR) Autophagy Metabolic Disease Inflammation/Immunology
    Atorvastatin hemicalcium trihydrate is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium trihydrate inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively .
    Atorvastatin hemicalcium <em>trihydrate</em>
  • HY-W088069

    Biochemical Assay Reagents Others
    Dipotassium hydrogen phosphate trihydrate, which is commonly used as a buffer and source of phosphorus and potassium in various applications, such as fertilizers, food processing, and pharmaceuticals, in biochemistry and molecular biology, Dipotassium hydrogen phosphate trihydrate is used in the preparation of cell culture media And reagent buffer system, in addition, it has been used in analytical chemistry as a reagent for the determination of calcium and magnesium ions in water samples.
    Dipotassium hydrogen phosphate <em>trihydrate</em>
  • HY-121272AS

    Bacterial Antibiotic Infection Inflammation/Immunology
    Difloxacin-d3 (hydrochloride trihydrate) is a deuterium labeled Difloxacin. Difloxacin is an antimicrobial agent[1].
    Difloxacin-d3 hydrochloride <em>trihydrate</em>
  • HY-131165

    Antibiotic Bacterial Infection
    Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
    Amoxicillin <em>trihydrate</em> mixture with potassium clavulanate (4:1)
  • HY-B0467B
    Amoxicillin trihydrate
    10+ Cited Publications

    Amoxycillin trihydrate

    Bacterial Antibiotic Infection
    Amoxicillin (Amoxycillin) trihydrateis an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin trihydrateis inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth .
    Amoxicillin <em>trihydrate</em>
  • HY-W127447

    Maleic acid sodium

    Biochemical Assay Reagents Others
    Maleic acid sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Maleate <em>trihydrate</em> sodium
  • HY-W008145

    Sodium tetrachloropalladate(II) trihydrate

    Biochemical Assay Reagents Others
    Sodium tetrachloropalladate(II) is an organic compound commonly used as a catalyst and as a raw material for dye production. It can be used to catalyze or promote reactions in certain chemical reactions, and is widely used in the fields of organic synthesis and dye preparation. In addition, the compound is also used for metallization, silver plating and electroplating of circuit boards.
    Sodium tetrachloropalladate(II)
  • HY-14542
    Ziprasidone
    1 Publications Verification

    CP-88059

    5-HT Receptor Dopamine Receptor Neurological Disease
    Ziprasidone (CP-88059), an orally active antipsychotic agent, is a combined 5-HT and dopamine receptor antagonist . Ziprasidone mesylate trihydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM) .
    Ziprasidone
  • HY-101634

    HCV Infection
    ABT-072 is an orally active and potent non-nucleoside HCV NS5B polymerase inhibitor (HCV GT1a EC50=1 nM; HCV GT1b EC50=0.3 nM) .
    ABT-072

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