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Results for "

uncoating

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Fluorescent Dye

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125713

    Glucosidase Enterovirus Infection
    Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating .
    Ganoderic acid Y
  • HY-N6025

    Influenza Virus Infection Inflammation/Immunology
    Clemastanin B, a lignin, has potent anti-influenza activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities .
    Clemastanin B
  • HY-19952

    VP 63843; Win 63843

    Enterovirus Infection
    Pleconaril is a picornavirus capsid binding inhibitor that prevents attachment and/or virus uncoating. Pleconaril has potential for use in rhinoviruses and enteroviruses research .
    Pleconaril
  • HY-104074
    Pocapavir
    3 Publications Verification

    SCH-48973; V-073

    Enterovirus Infection
    Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections .
    Pocapavir
  • HY-103078A

    HIV Infection
    I-XW-053 sodium is a potent HIV-1 inhibitor with an IC50 value of 164.2 μM. I-XW-053 sodium is a novel antiviral that targets a unique site on the HIV-1 CA protein and inhibits by affecting virus uncoating [1] .
    I-XW-053 sodium
  • HY-128382

    E 151

    Enterovirus Infection
    Brilliant black BN (E151) is an azo dye and a food colorant . Brilliant black BN is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A. Brilliant black BN has the potential for the investigation of contagious disease .
    Brilliant Black BN
  • HY-104074S

    SCH-48973-d3; V-073-d3

    Isotope-Labeled Compounds Others
    Pocapavir-d3 (SCH-48973-d3; V-073-d3)is the deuterium labeledPocapavir(HY-104074) . Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections .
    Pocapavir-d3
  • HY-120072
    PF-3450074
    3 Publications Verification

    PF-74

    HIV Infection
    PF-3450074 (PF-74) is a specifical inhibitor of HIV-1 capsid protein (CA) and displays a broad-spectrum inhibition of HIV isolates with submicromolar potency (EC50=8-640 nM). PF-3450074 (PF-74) acts at an early stage of HIV-1 infection, inhibits viral replication by directly competing with the binding of CPSF6 and NUP153, and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle . CPSF6: nuclear host factors cleavage and polyadenylation specific factor 6; NUP153: nucleoporin 153.
    PF-3450074

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