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viability

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179

Inhibitors & Agonists

10

Fluorescent Dye

8

Biochemical Assay Reagents

10

Peptides

5

MCE Kits

2

Inhibitory Antibodies

37

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0163
    Methyl Green

    		DNA Stain Others
    Methyl Green is a potent fluorescent dye. Methyl Green is a DNA stains of cells and electrophoretic gels. Methyl Green can be used as a stain for direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm .
    Methyl Green
  • HY-D0950A
    Methyl Green zinc chloride

    		DNA Stain Others
    Methyl Green zinc chloride is a potent fluorescent dye. Methyl Green zinc chloride is a DNA stains of cells and electrophoretic gels. Methyl Green zinc chloride can be used as direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm .
    Methyl Green zinc chloride
  • HY-N10131
    Biatractylolide

    (+)-Biatractylolide

    		 Apoptosis Neurological Disease Cancer
    Biatractylolide is a compound isolated from the ethyl acetate extract of Atractylodes macrocephala. Biatractylolide has antitumor and antioxidant activities. Biatractylolide improves cell viability, inhibits the apoptosis of cells induced by glutamate, and reduces the activity of LDH. Biatractylolide has neuroprotective effects .
    Biatractylolide
  • HY-143461
    CK2 inhibitor 3

    		Casein Kinase Cancer
    CK2 inhibitor 3 is a potent CK2 inhibitor with IC50 value of 280 nM. CK2 inhibitor 3 inhibits endocellular CK2, significantly affects viability of tumour cells and shows remarkable selectivity on a panel of 320 kinases .
    CK2 inhibitor 3
  • HY-119994
    DFPM

    		Others Others
    DFPM activates plant resistance protein signaling in roots, and triggers root growth arrest. DFPM decreases root cell viability in accession Col-0. DFPM is light sensitive in aqueous solutions. DFPM becomes bioactive during light and oxygen-dependent modification .
    DFPM
  • HY-N8481
    3,6-Dihydroxyflavone

    3,6-DHF

    		 Apoptosis Cancer
    3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation .
    3,6-Dihydroxyflavone
  • HY-120046
    YF479

    		HDAC Cancer
    YF479 is a potent inhibitor of histone deacetylase. YF479 abates cell viability, suppresses colony formation and tumor cell motility. YF479 significantly inhibits breast tumor growth and metastasis. YF479 has the potential for the research of clinical trials for breast cancer .
    YF479
  • HY-118540
    Resazurin

    Diazoresorcinol

    		 Fluorescent Dye Others
    Resazurin (Diazoresorcinol) is a water-soluble, non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) .
    Resazurin
  • HY-144775
    AChE-IN-10

    		Cholinesterase (ChE) Neurological Disease
    AChE-IN-10 (Compound 24r) is a potent inhibitor of AChE (IC50 = 2.4 nM). AChE-IN-10 potently inhibits AChE, reduces tau phosphorylation at S396 residue, provides neuroprotection by rescuing neuronal morphology and increasing cell viability. AChE-IN-10 is also found to reduce amyloid aggregation in the presence of AChE .
    AChE-IN-10
  • HY-162274
    Oxazepine

    		Hedgehog Antibiotic Infection Cancer
    Oxazepine (compound 4a) has antimicrobial viability via binding OMPA/ exo-1,3-beta-glucanase proteins. Oxazepine is a hedgehog signaling inhibitor with antitumor viability .
    Oxazepine
  • HY-107992
    Iotrolan

    		Others Others
    Iotrolan is a tradiocontrast agent. Iotrolan has no effect on NP cell viability or induce apoptosis .
    Iotrolan
  • HY-137949
    Formoxanthone A

    		Apoptosis Cancer
    Formoxanthone A is an apoptosis inducing compound that can significantly reduce the viability of HeLa cells at 25 μM .
    Formoxanthone A
  • HY-N1447
    Ganoderic acid A
    4 Publications Verification

    		 Apoptosis Autophagy Endogenous Metabolite Cancer
    Ganoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.
    Ganoderic acid A
  • HY-118495
    Cardol diene

    		Parasite Infection
    Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .
    Cardol diene
  • HY-111391
    Resazurin sodium
    3 Publications Verification

    Diazoresorcinol sodium

    		 Bacterial Others
    Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.
    Resazurin sodium
  • HY-N8293
    Eupalinolide I

    		Others Cancer
    Eupalinolide I inhibits the viability of breast cancer cells. Eupalinolide I can be isolated from Eupatorium lindleyanum .
    Eupalinolide I
  • HY-12808
    STF-118804
    1 Publications Verification

    		 NAMPT Apoptosis Cancer
    STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.
    STF-118804
  • HY-153235
    COVID-19 Spike Protein mRNA-LNP

    		SARS-CoV Liposome Infection
    COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing COVID-19 Spike Protein, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. COVID-19 Spike Protein is the novel coronavirus pneumonia spike protein located on the membrane surface. COVID-19 Spike Protein undertakes the functions of virus binding to host cell membrane receptors and membrane fusion, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design .
    COVID-19 Spike Protein mRNA-LNP
  • HY-120766
    NCDM-32B

    		Histone Demethylase Cancer
    NCDM-32B is a potent and selective KDM4 inhibitor that impaires viability and transforming phenotypes of breast cancer .
    NCDM-32B
  • HY-118961
    SR31527 chloride

    		Kinesin Cancer
    SR31527 chloride is a potent KIFC1 inhibitor with an IC50 value of 6.6 µM. SR31527 chloride decreases cell viability and colony formation .
    SR31527 chloride
  • HY-153745
    Protein kinase inhibitor 5

    		Trk Receptor Cancer
    Protein kinase inhibitor 5 is a potent TRK-A inhibitor with an IC50 value of 1.8 nM. Protein kinase inhibitor 5 inhibits cell viability .
    Protein kinase inhibitor 5
  • HY-P2576
    Polistes mastoparan

    		Bacterial Infection
    Polistes mastoparan is an antimicrobial peptide. Polistes mastoparan increases S. aureus cell K + efflux and inhibits cell viability with EC50 of 5 μM .
    Polistes mastoparan
  • HY-124866
    PDI-IN-3

    		PDI Neurological Disease
    PDI-IN-3 (compound 16F16) is a protein disulfide isomerase (PDI) inhibitor. PDI-IN-3 inhibits cell viability .
    PDI-IN-3
  • HY-P5205
    Garvicin KS, GakA

    		Bacterial Infection
    Garvicin KS, GakA is a peptide at sizes of 34 amino acids to form bacteriocin garvicin KS (GarKS), with other 2 peptides, GakB, and GakC. Garvicin KS, GakA inhibits fibroblast viability and proliferation. Garvicin KS, GakA with GakB, is a potent combination with good peptide stability, antimicrobial efficacy, and fibroblast viability/proliferation effects. Garvicin KS peptides inhibit MSSA with MIC values in the order GakB >GakC >GakA .
    Garvicin KS, GakA
  • HY-P5206
    Garvicin KS, GakB

    		Bacterial Infection
    Garvicin KS, GakB is a peptide at sizes of 34 amino acids to form bacteriocin garvicin KS (GarKS), with other 2 peptides, GakA, and GakC. Garvicin KS, GakB inhibits fibroblast viability and proliferation. Garvicin KS, GakB with GakA, is a potent combination with good peptide stability, antimicrobial efficacy, and fibroblast viability/proliferation effects. Garvicin KS peptides inhibit MSSA with MIC values in the order GakB >GakC >GakA .
    Garvicin KS, GakB
  • HY-12444
    Y15
    15+ Cited Publications

    FAK Inhibitor 14

    		 FAK Cancer
    Y15 is a potent and specific inhibitor of focal adhesion kinase (FAK) that inhibits its autophosphorylation activity, decreases the viability of cancer cells, and blocks tumor growth.
    Y15
  • HY-19832
    SC66
    5 Publications Verification

    		 Akt Apoptosis Cancer
    SC66 is an Akt inhibitor, reduces cell viability in a dose- and time-dependent manner, inhibits colony formation and induces apoptosis in hepatocellular carcinoma (HCC) cells.
    SC66
  • HY-78884
    Anticancer agent 9

    		Amino Acid Derivatives Cancer
    Anticancer agent 9, a glycine derivative, is an anticancer agent. Anticancer agent 9 can inhibit tumor cells viability of myelogenous leukemia and human prostate cancer .
    Anticancer agent 9
  • HY-122131
    XTT sodium

    		Others Others
    XTT (sodium) is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble XTT to a water-soluble, orange colored formazan product.
    XTT sodium
  • HY-153745A
    Protein kinase inhibitor 5 sulfate hydrate

    		Trk Receptor Cancer
    Protein kinase inhibitor 5 sulfate hydrate is a potent TRK-A inhibitor with an IC50 value of 1.8 nM. Protein kinase inhibitor 5 sulfate hydrate inhibits cell viability .
    Protein kinase inhibitor 5 sulfate hydrate
  • HY-P9962
    Efungumab

    		Fungal Infection
    Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC) .
    Efungumab
  • HY-D0830
    Calcein (tetraethyl ester)

    Fluorexon tetraethyl ester

    		 Fluorescent Dye Others
    Calcein tetraethyl ester is a fluorescent dye, is used in biology as it can be transported through the cellular membrane into live cells, which makes it useful for testing of cell viability and for short-term labeling of cells.
    Calcein (tetraethyl ester)
  • HY-N2140
    Herpetone

    Herpetone, the ethylacetate extract, is a lignan compound. Herpetone can be isolated from the seeds of Herpetospermum caudigerum. Herpetone significantly improved the cell viability, and has a protective effect on hepatocytes in vitro .
    Herpetone
  • HY-100932
    ML-9
    2 Publications Verification

    		 Myosin Cancer
    ML-9 is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity . ML-9 inhibits inhibits MLCK, PKA and PKC activity with Ki values of 4, 32 and 54 μM, respectively . ML-9 induces autophagy by stimulating autophagosome formation and inhibiting their degradation .
    ML-9
  • HY-100932A
    ML-9 Free Base

    		Myosin Cancer
    ML-9 (Free Base) is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity . ML-9 (Free Base) inhibits inhibits MLCK, PKA and PKC activity with Ki values of 4, 32 and 54 μM, respectively . ML-9 (Free Base) induces autophagy by stimulating autophagosome formation and inhibiting their degradation .
    ML-9 Free Base
  • HY-145111
    TNK2-IN-1

    		Tyrosinase Cancer
    TNK2-IN-1 is a TNK2 inhibitor. TNK2-IN-1 has an IC50 of 224 nM for TNK2. TNK2-IN-1 can be used for the research of cancer .
    TNK2-IN-1
  • HY-N7678
    Gypenoside LXXV
    1 Publications Verification

    		 Others Cancer
    Gypenoside LXXV, isolated from Gynostemma pentaphyllum, is one of the deglycosylated shapes of ginsenoside Rb1. Gypenoside LXXV significantly reduces cancer cell viability and displays an anti-cancer effect .
    Gypenoside LXXV
  • HY-N7825
    Gomisin L1

    		Others Cancer
    Gomisin L1 is a lignan, shows inhibitory effect on cell viability of A2780 and Ishikawa cells, with IC50s of 39.06 μM and 74.16 μM, respectively .
    Gomisin L1
  • HY-156883
    Dasatinib analog-1

    		Cytochrome P450 Others
    Dasatinib analog-1 (compound 5826) inhibits CYP3A4 viability with a Ki value of 5.4 μM. Dasatinib analog-1 blocks the formation of glutathione adducts .
    Dasatinib analog-1
  • HY-D1116
    MitoMark Red I

    		Fluorescent Dye Others
    MitoMark Red I is a fluorescent mitochondrial marker. MitoMark Red I is a red fluorescent dye which accumulates in mitochondria in viable cells and has an excitation wavelength of 578 nm and emission of 599 nm .
    MitoMark Red I
  • HY-N10563
    Coleon-U-quinone

    		P-glycoprotein Cancer
    Coleon-U-quinone is a potent P-gp inhibitor. Coleon-U-quinone can inhibit cancer cells viability and sensitize multidrug resistance cancer cells to Doxorubicin (HY-15142A) .
    Coleon-U-quinone
  • HY-146810
    PRMT4-IN-1

    		Histone Methyltransferase Cancer
    PRMT4-IN-1 is a selective inhibitor of PRMT4 (IC50=3.2 nM). PRMT4-IN-1 inhibits MCF7 relative viability .
    PRMT4-IN-1
  • HY-143334
    Antifungal agent 84

    		Fungal Infection
    Antibacterial agent 84 is an antifungal compound. Antibacterial agent 84 inhibits candidiasis in a CNB1-dependent way. Antibacterial agent 84 inhibits the C. albicans biofilm's viability .
    Antifungal agent 84
  • HY-156502
    TINK-IN-1

    		Others Cancer
    TINK-IN-1 (Compound 9) is a potent and selective Traf2- and Nck-interacting kinase (TNIK) inhibitor with an IC50 of 8 nM. TINK-IN-1 inhibits colorectal cancer cells viability .
    TINK-IN-1
  • HY-12461
    WS6

    		Others Inflammation/Immunology
    WS6 is a novel small molecule that promotes β cell proliferation in rodent and human primary islets with EC50 of 0.28 uM(R7T1 cell viability).
    WS6
  • HY-120495
    EP6

    		Lipoxygenase Cancer
    EP6 is a potent 5-Lipoxygenase (5-LO) inhibitor. EP6 inhibits the cell viability of tumor cells without mutagenic activity. EP6 can be used in research of cancer .
    EP6
  • HY-N8754
    (7S)-Dalbergiphenol

    		Others Cardiovascular Disease Cancer
    (7S)-Dalbergiphenol is a cytotoxic compound that can be isolated from Brazilian red propoli. (7S)-Dalbergiphenol inhibits cancer cell viability. Brazilian red propoli has cardioprotective activity .
    (7S)-Dalbergiphenol
  • HY-161252
    PBD-monoamide

    		ADC Cytotoxin Cancer
    PBD-monoamide, a modified PBD (pyrrolobenzodiazepine) dimer, is an ADC Cytotoxin. PBD-monoamide can be used for synthesis of DHES0815A (an HER2 ADC). PBD-monoamide has DNA-binding activity and reduces cell viability .
    PBD-monoamide
  • HY-139971
    Antibacterial agent 64

    		Bacterial Infection
    Antibacterial agent 64 (compound 62) is a potent YycG inhibitor (IC50=6.1 µM) and an antibacterial agent. Antibacterial agent 64 combines with ampicillin could synergistically eradicate the biofilm-embedded viable bacteria .
    Antibacterial agent 64
  • HY-162164
    Neuroprotective agent 3

    		Others Neurological Disease
    Neuroprotective agent 3 (Compound 21a) is an antioxidant that exhibits neuroprotective effects. Neuroprotective agent 3 significantly increases neuronal viability and induces neuroprotection, as well as improves neurological deficit scores in an in vivo model of transient cerebral ischemia .
    Neuroprotective agent 3

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