Search Result

Search Result

Results for "

vinca

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (4) Calcium Channel (3) Drug Metabolite (1) Isotope-Labeled Compounds (2) Microtubule/Tubulin (5)
By Research Areas:	Cancer (9) Cardiovascular Disease (4) Neurological Disease (3)

11

Inhibitors & Agonists

7

Natural
Products

3

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1180

Vinburnine

(-)-Eburnamonine; (-)-vincamone
Drug Metabolite Cardiovascular Disease

Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.
HY-N0687

Vindoline

Microtubule/Tubulin Cancer

Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus, weakly inhibits tubulin self-assembly .

Catharanthine (+)-3,4-Didehydrocoronaridine	Calcium Channel	Cardiovascular Disease Neurological Disease Cancer
Catharanthine ((+)-3,4-Didehydrocoronaridine), a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca ²⁺ channel (VOCC). Catharanthine has IC₅₀s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine lowers blood pressure (BP), heart rate (HR). Catharanthine has anti-cancer activity .

Catharanthine Tartrate (+)-3,4-Didehydrocoronaridine Tartrate	Calcium Channel	Cardiovascular Disease Neurological Disease Cancer
Catharanthine ((+)-3,4-Didehydrocoronaridine) Tartrate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca ²⁺ channel (VOCC). Catharanthine Tartrate has IC₅₀s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Tartrate lowers blood pressure (BP), heart rate (HR). Catharanthine Tartrate has anti-cancer activity .

HY-N1236

Sitsirikine

Sitsirikin

Sitsirikine is a Vinca alkaloid .

Catharanthine Sulfate (+)-3,4-Didehydrocoronaridine Sulfate	Calcium Channel	Cardiovascular Disease Neurological Disease Cancer
Catharanthine ((+)-3,4-Didehydrocoronaridine) Sulfate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca ²⁺ channel (VOCC). Catharanthine Sulfate has IC₅₀s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Sulfate lowers blood pressure (BP), heart rate (HR). Catharanthine Sulfate has anti-cancer activity .

Vincristine sulfate 35+ Cited Publications Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate	Microtubule/Tubulin Apoptosis	Cancer
Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a K_i of 85 nM.

Vincristine-d6 sulfate Leurocristine-d₆ sulfate; NSC-67574-d₆ sulfate; 22-Oxovincaleukoblastine-d₆ sulfate	Isotope-Labeled Compounds Microtubule/Tubulin Apoptosis	Cancer
Vincristine-d₆ (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.

Halichondrin B	Others	Cancer
Halichondrin B is found from the sponge Halichondria okadai. Halichondrin B is a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin (IC₅₀ for tubulin polymerization of 1.2-1.4 μM). Halichondrin B shows anti-tumor activity .

Vincristine-d3 sulfate Leurocristine-d₃ sulfate; NSC-67574-d₃ sulfate; 22-Oxovincaleukoblastine-d₃ sulfate	Isotope-Labeled Compounds Microtubule/Tubulin Apoptosis	Cancer
Vincristine-d₃ (sulfate)is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM[1][2].

Vincristine-d3-ester sulfate Leurocristine-d₃-ester sulfate; NSC-67574-d₃-ester sulfate; 22-Oxovincaleukoblastine-d₃-ester sulfate	Microtubule/Tubulin Apoptosis	Cancer
Vincristine-d₃-ester (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM[1].

Cat. No.	Product Name	Category	Target	Chemical Structure

Vinburnine (-)-Eburnamonine; (-)-vincamone	Apocynaceae Cardiovascular Disease Alkaloids Structural Classification Classification of Application Fields Hunteria zeylanica Source classification Plants Disease Research Fields Indole Alkaloids	Drug Metabolite
Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.

Vindoline	Apocynaceae Alkaloids Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids Cancer Catharanthus roseus (L.) G. Don	Microtubule/Tubulin
Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus, weakly inhibits tubulin self-assembly .

Catharanthine (+)-3,4-Didehydrocoronaridine	Cardiovascular Disease Apocynaceae Alkaloids Structural Classification Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids Catharanthus roseus (L.) G. Don	Calcium Channel
Catharanthine ((+)-3,4-Didehydrocoronaridine), a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca ²⁺ channel (VOCC). Catharanthine has IC₅₀s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine lowers blood pressure (BP), heart rate (HR). Catharanthine has anti-cancer activity .

Catharanthine Tartrate (+)-3,4-Didehydrocoronaridine Tartrate	Cardiovascular Disease Apocynaceae Alkaloids Structural Classification Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids Cancer Catharanthus roseus (L.) G. Don	Calcium Channel
Catharanthine ((+)-3,4-Didehydrocoronaridine) Tartrate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca ²⁺ channel (VOCC). Catharanthine Tartrate has IC₅₀s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Tartrate lowers blood pressure (BP), heart rate (HR). Catharanthine Tartrate has anti-cancer activity .

Catharanthine Sulfate (+)-3,4-Didehydrocoronaridine Sulfate	Cardiovascular Disease Apocynaceae Alkaloids Structural Classification Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids Catharanthus roseus (L.) G. Don	Calcium Channel
Catharanthine ((+)-3,4-Didehydrocoronaridine) Sulfate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca ²⁺ channel (VOCC). Catharanthine Sulfate has IC₅₀s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Sulfate lowers blood pressure (BP), heart rate (HR). Catharanthine Sulfate has anti-cancer activity .

Vincristine sulfate 35+ Cited Publications Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate	Apocynaceae Alkaloids Classification of Application Fields Anti-aging Source classification Plants Disease Research Fields Alkaloid Dimers Cancer Catharanthus roseus (L.) G. Don	Microtubule/Tubulin Apoptosis
Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a K_i of 85 nM.

Halichondrin B	Structural Classification Natural Products Classification of Application Fields Animals Marine natural products Sponge Disease Research Fields Cancer	Others
Halichondrin B is found from the sponge Halichondria okadai. Halichondrin B is a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin (IC₅₀ for tubulin polymerization of 1.2-1.4 μM). Halichondrin B shows anti-tumor activity .

Cat. No.	Product Name	Chemical Structure

Vincristine-d3-ester sulfate
Vincristine-d₃-ester (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM[1].

Vincristine-d6 sulfate
Vincristine-d₆ (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.

Vincristine-d3 sulfate
Vincristine-d₃ (sulfate)is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM[1][2].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

MedChemExpress Magic Cece

MedChemExpress: Contact Us; About Us; Headquarters; Distributors; Statement on False Report; Careers

Customer Support: Technical Support; Service; Ordering Information; Easy Return; Shipping Rates & Policies; Intellectual Property Promise

Resources: Free Sample; Resources; Molarity Calculator; Dilution Calculator; Terms & Conditions; Reconstitution Calculator; Specific Activity Calculator

Subscribe to our E-newsletter

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

Copyright © 2013-2024 MedChemExpress. All Rights Reserved.: Site Map Privacy Policy

Join with us