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αMβ2

" in MedChemExpress (MCE) Product Catalog:

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Cat. No. Compare Product Name Species Source
  • HY-P700759
    Integrin alpha M beta 2 Protein, Human (HEK293, His)

    αMβ2; ITGAM&ITGB2; ITGAM; ITGB2; Mac-1; complement receptor-3 (CR3)

    		 Human HEK293
    Integrin α M β 2 (ITGAM/ITGB2) mediates adhesion of monocytes and granulocytes and promotes uptake of complement-coated particles and pathogens. As a receptor for iC3b and fibrinogen, it regulates neutrophil migration, contributes to CD177-PRTN3-mediated activation, and may influence phagocytosis-induced apoptosis. Integrin alpha M beta 2 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha M beta 2 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha M beta 2 Protein, Human (HEK293, His), has molecular weight of 140-160 kDa (ITGAM) & 90-100 kDa (ITGB2), respectively.
  • HY-P76143
    AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST)

    5'-AMP-activated protein kinase; AMPK; AMPK (α1, β2, γ1) Protein

    		 Human Sf9 insect cells
    The AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), a crucial regulator of cellular energy metabolism. Activated by low ATP levels, it enhances energy production while suppressing biosynthetic processes and cell growth. The gamma subunit mediates AMP, ADP, and ATP binding, influencing AMPK activation or inhibition. Allosteric AMP binding activates the alpha subunit, while ADP stimulates phosphorylation, and ATP promotes dephosphorylation, rendering AMPK inactive. Additionally, AMPK modulates cellular polarity and interacts with FNIP1 and FNIP2. AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 2/alpha 1 Heterotrimer protein, expressed by Sf9 insect cells, with N-His, N-GST labeled tag. AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~35 & 37 & 95 KDa, respectively.
  • HY-P701702
    AMP Kinase β2 Protein, Human (His)

    PRKAB2; 5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2

    		 Human E. coli
    AMP kinase β2 protein is the non-catalytic subunit of AMP-activated protein kinase (AMPK), which regulates cellular energy metabolism. When a decrease in ATP levels is detected, AMPK activates energy-generating pathways and inhibits biosynthesis and cell growth. AMP Kinase β2 Protein, Human (His) is the recombinant human-derived AMP Kinase β2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of AMP Kinase β2 Protein, Human (His) is 271 a.a., .
  • HY-P78521
    SIRP gamma Protein, Human (HEK293, His-Avi)

    CD172g; FLJ42230; SIRP beta 2; SIRP gamma; SIRP-B2; SIRPG; Cripto-1; bA77C3.1; SIRP β 2

    		 Human HEK293
    SIRP gamma Protein, a probable immunoglobulin-like cell surface receptor, mediates cell-cell adhesion by binding with CD47. This interaction enhances antigen-specific T-cell proliferation and provides costimulatory signals for T-cell activation, highlighting SIRP gamma's role in modulating immune responses. The intricate interactions with CD47 underscore SIRP gamma's significance as a cell surface receptor, crucial in cellular adhesion and regulating T-cell activation pathways. SIRP gamma Protein, Human (HEK293, His-Avi) is the recombinant human-derived SIRP gamma protein, expressed by HEK293, with C-His, C-Avi labeled tag. The total length of SIRP gamma Protein, Human (HEK293, His-Avi) is 332 a.a., with molecular weight of 47-49 kDa.
  • HY-P78210
    SIRP gamma Protein, Human (Biotinylated, HEK293, His-Avi)

    CD172g; FLJ42230; SIRP beta 2; SIRP gamma; SIRP-B2; SIRPG; Cripto-1; bA77C3.1; SIRP β 2

    		 Human HEK293
    SIRP γ protein is a possible immunoglobulin-like cell surface receptor that mediates cell-cell adhesion by binding to CD47. This interaction enhances antigen-specific T cell proliferation and provides costimulatory signals for T cell activation, highlighting the role of SIRP gamma in regulating immune responses. SIRP gamma Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived SIRP gamma protein, expressed by HEK293 , with C-His, C-Avi labeled tag. The total length of SIRP gamma Protein, Human (Biotinylated, HEK293, His-Avi) is 332 a.a., with molecular weight of 48-53 kDa.
  • HY-P76144
    AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST)

    5'-AMP-activated protein kinase; AMPK; AMPK (α2, β2, γ1) Protein

    		 Human Sf9 insect cells
    The AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), a crucial regulator of cellular energy metabolism. Activated by low ATP levels, it enhances energy production while suppressing biosynthetic processes and cell growth. The gamma subunit mediates AMP, ADP, and ATP binding, influencing AMPK activation or inhibition. Allosteric AMP binding activates the alpha subunit, while ADP stimulates phosphorylation, and ATP promotes dephosphorylation, rendering AMPK inactive. Additionally, AMPK modulates cellular polarity and interacts with FNIP1 and FNIP2. AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 2/alpha 2 Heterotrimer protein, expressed by Sf9 insect cells, with N-His, N-GST labeled tag. AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~35 & 37 & 95 KDa, respectively.
  • HY-P73304
    NRG1-beta 2 Protein, Human

    NRG-1 EGF-like domain beta 2; Beta2; Neuregulin-1 beta 2

    		 Human E. coli
    NRG1-alpha protein acts as a direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concurrently recruiting ERBB1 and ERBB2 coreceptors, thereby inducing ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The diverse functions of its multiple isoforms encompass the induction of growth and differentiation in various cell types, including epithelial, glial, neuronal, and skeletal muscle cells. NRG1-alpha is also involved in the expression of acetylcholine receptors during neuromuscular junction formation, the stimulation of lobuloalveolar budding and milk production in the mammary gland, and the induction of differentiation in mammary tumor cells. Furthermore, it stimulates Schwann cell proliferation and plays a role in myocardial development, specifically contributing to the trabeculation of the developing heart. Isoform 10 is implicated in motor and sensory neuron development. NRG1-alpha binds to ERBB4 and ERBB3, acting as a ligand for integrins and forming a ternary complex with integrins and ERBB3, a crucial step in NRG1-ERBB signaling. It induces the phosphorylation and activation of MAPK3/ERK1, MAPK1/ERK2, and AKT1. Additionally, NRG1-alpha participates in ligand-dependent ERBB4 endocytosis, essential for the activation of these kinases in neurons, and interacts with the LIM domain region of LIMK1. It also forms a ternary complex with ERBB3 and integrins ITGAV:ITGB3 or ITGA6:ITGB4 and interacts with NRDC and BACE1. NRG1-beta 2 Protein, Human is the recombinant human-derived NRG1-beta 2 protein, expressed by E. coli , with tag free. The total length of NRG1-beta 2 Protein, Human is 61 a.a., with molecular weight of ~7.0 kDa.
  • HY-P71315
    SIRP beta 2 Protein, Human (HEK293, Fc)

    dJ776F14.2; PTPN1L; PTPNS1L3; Signal-Regulatory Protein Beta 2; Signal-Regulatory Protein Beta-2; SIRP beta 2; SIRP-beta-2; SIRPG

    		 Human HEK293
    SIRP beta 2 Protein, a novel positive regulator of innate immunotherapy, is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP beta 2 is expressed on myeloid cells at protein level and enhanced adhesion, differentiation, cancer cell phagocytosis and T cell activation in an in vitro setting. DAP12 is responsible for SIRP beta 2 signaling, and is recruited through a single, positive lysine residue in the transmembrane domain of SIRP beta 2. SIRP beta 2 Protein, Human (HEK293, Fc) is the recombinant human-derived SIRP beta 2 protein, expressed by HEK293, with C-hFc labeled tag. The total length of SIRP beta 2 Protein, Human (HEK293, Fc) is 255 a.a., with molecular weight of 80-95 kDa.
  • HY-P7119
    TGF beta 2/TGFB2 Protein, Human
    5 Publications Verification

    TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2

    		 Human HEK293
    Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Human is produced in HEK293 cells, and consists of 112 amino acids (A303-S414).
  • HY-P700857
    GARP&Latent TGF Beta 2 Complex Protein, Human (HEK293, His-Avi)

    Garpin; GARP; LRRC32; D11S833E; GARP&Latent TGF B; GARP&TGF B; Cetermin; G-TSF; LAP; TGF-beta-2; TGF Beta 2; GARP&Latent TGF Beta 2

    		 Human HEK293
    LRRC32, a key regulator of TGF-beta activation, maintains TGFB1, TGFB2, and TGFB3 in a latent state during extracellular storage by binding to Latency-associated peptide (LAP). Competing with LTBP1 for LAP binding, LRRC32 effectively modulates integrin-dependent TGF-beta activation. Its significance spans the regulation of TGF-beta-1 (TGFB1) on activated Tregs' surface and the control of TGF-beta-3 (TGFB3) during palate development, emphasizing LRRC32's intricate role in fine-tuning TGF-beta signaling. Interactions with TGFB1, TGFB2, TGFB3, and LAPTM4B contribute to its regulatory functions. GARP&Latent TGF Beta 2 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP&Latent TGF Beta 2 Complex protein, expressed by HEK293, with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 2 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 72-77 kDa(GARP) & 13 kDa & 46-48 kDa(Latent TGF Beta 2), respectively.
  • HY-P700785
    TGF beta 2/TGFB2 Protein, Human (HEK293, Avi)
    1 Publications Verification

    TGFB2; TGFBR2; TGFR2; TbetaR-II; TGFβR2; BB105277; TGF-beta 2; TβR-II; TGF-β 2

    		 Human HEK293
    In the TGF-beta-2 pathway, TGF beta 2/TGFB2 protein acts as a precursor for Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2), regulating their formation. Crucially, TGF beta 2/TGFB2 maintains TGF-beta-2 in a latent state within the extracellular matrix, forming non-covalent associations with TGF-beta-2. Interactions with 'milieu molecules' like LTBP1 and LRRC32/GARP finely tune TGF-beta-2 activation, playing a pivotal role in controlling this critical signaling pathway. TGF beta 2/TGFB2 Protein, Human (HEK293, Avi) is the recombinant human-derived TGF beta 2/TGFB2 protein, expressed by HEK293, with C-Avi labeled tag. The total length of TGF beta 2/TGFB2 Protein, Human (HEK293, Avi) is 112 a.a., with molecular weight of 14.53 kDa.
  • HY-P72596
    IL-12R beta 2 Protein, Mouse (HEK293, Fc)

    Interleukin-12 receptor subunit beta-2; IL-12R-beta-2; IL-12RB2

    		 Mouse HEK293
    IL-12R beta 2 protein is an IL-12 cytokine surface receptor that activates the Jak-Stat signaling cascade pathway and is involved in IL-12-mediated immune regulation. IL-12R beta 2 Protein, Mouse (HEK293, Fc) is expressed by HEK 293 cells with a transmembrane region (W638-I658) and a hFc tag at the C-terminus.
  • HY-P73863
    Integrin alpha X beta 2 Protein, Human (HEK293, His)

    Integrin alpha X beta 2; CD11c; ITGAX; CD18; ITGB2

    		 Human HEK293
    Integrin alpha-X/beta-2, a receptor for fibrinogen, crucially recognizes the G-P-R sequence. It plays a pivotal role in inflammatory responses, especially in monocyte adhesion and chemotaxis. Structurally, forming a heterodimer, the alpha-X subunit associates with the beta-2 subunit. This receptor's fibrinogen recognition underscores its significance in immune responses, emphasizing its role in regulating monocyte functions and cell migration during inflammation. Integrin alpha X beta 2 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha X beta 2 Protein, Human (HEK293, His), has molecular weight of 130-150 kDa (ITGAX) & 85-96 kDa (ITGB2), respectively.
  • HY-P74834
    IL-12R beta 2 Protein, Mouse (HEK293, His)

    Interleukin-12 receptor subunit beta-2; IL-12R-beta-2; IL-12RB2

    		 Mouse HEK293
    IL-12R beta 2 protein is an IL-12 cytokine surface receptor that activates the Jak-Stat signaling cascade pathway and is involved in IL-12-mediated immune regulation. IL-12R beta 2 Protein, Mouse (HEK293, His) is expressed by HEK 293 cells with a transmembrane region (W638-I658) and a His tag at the C-terminus.
  • HY-P702206
    ADRB2 Protein, Human (Cell-Free, His, SUMO)

    Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor

    		 Human E. coli Cell-free
    ADRB2 protein is an important member of the β-adrenergic receptor family and mediates catecholamine-induced adenylyl cyclase activation through G protein action. It has 30 times greater affinity for epinephrine and plays a crucial role in cellular responses to sympathetic nervous system stimulation. ADRB2 Protein, Human (Cell-Free, His, SUMO) is the recombinant human-derived ADRB2 protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag and G16R, E27Q, , , mutation. The total length of ADRB2 Protein, Human (Cell-Free, His, SUMO) is 413 a.a., with molecular weight of 65 kDa.
  • HY-P73864
    Integrin alpha X beta 2 Protein, Human (HEK293, Flag-His)

    Integrin alpha X beta 2; CD11c; ITGAX; CD18; ITGB2

    		 Human HEK293
    Integrin alpha-X/beta-2, a receptor for fibrinogen, crucially recognizes the G-P-R sequence. It plays a pivotal role in inflammatory responses, especially in monocyte adhesion and chemotaxis. Structurally, forming a heterodimer, the alpha-X subunit associates with the beta-2 subunit. This receptor's fibrinogen recognition underscores its significance in immune responses, emphasizing its role in regulating monocyte functions and cell migration during inflammation. Integrin alpha X beta 2 Protein, Human (HEK293, Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha X beta 2 protein, expressed by HEK293, with C-His, C-Flag labeled tag. Integrin alpha X beta 2 Protein, Human (HEK293, Flag-His), has molecular weight of ~95 & 130 kDa, respectively.
  • HY-P73614
    TGF beta 2/TGFB2 Protein, Canine (HEK293, His)

    TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2

    		 Canine HEK293
    Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Canine (HEK293, His) is produced in HEK293 cells  with a C-Terminal His-tag. It and consists of 414 amino acids (M1-S414).
  • HY-P78240
    B2M/Beta-2 microglobulin Protein, Mouse (HEK293, Fc)

    Beta-2-microglobulin; B2M; β-2-microglobulin

    		 Mouse HEK293
    Beta-2 microglobulin (B2M) is vital in presenting antigens to the immune system through MHC class I molecules. It forms a heterodimer with an alpha chain to create MHC class I molecules. B2M also forms a heterotrimer with MR1 and a metabolite antigen, enhancing antigen presentation and immune recognition. B2M's molecular interactions facilitate immune system functioning and foreign substance recognition. B2M/Beta-2 microglobulin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Mouse (HEK293, Fc) is 99 a.a., with molecular weight of 40-50 kDa.
  • HY-P73613
    TGF beta 2/TGFB2 Protein, Rhesus Macaque (HEK293, His)

    TGF-beta-2; Cetermin; G-TSF; TGFB2; Polyergin; rHuTGF-β2

    		 Rhesus Macaque HEK293
    Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Rhesus Macaque (HEK293, His) is produced in HEK293 cells  with a C-Terminal His-tag. It and consists of 414 amino acids (M1-S414).
  • HY-P7299
    TGF beta 2/TGFB2 Protein, Mouse/Rat (HEK293)-1

    rMuTGF-β2; TGFB2; LAP

    		 Mouse HEK293
    TGFB2 Protein, Mouse/Rat (HEK293) performs many cellular functions and has a vital role during embryonic development.
  • HY-P70649
    TGF beta 2/TGFB2 Protein, Mouse/Rat (HEK293)
    1 Publications Verification

    TGFB2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; MGC116892; Polyergin; TGF-beta2; TGF-beta-2; transforming growth factor beta-2

    		 Mouse;Rat HEK293
    Transforming growth factor-beta 2 (TGF-β2), an extracellular glycosylated protein, is a member of the TGF-β superfamily. TGFβ2 controls key physiological processes including cell migration, proliferation and differentiation via signalling through type I and type II receptors (TGFβR1 and TGFβR2). TGF-β2 is an immune suppressor involved in the development of immune tolerance, and also regulates embryonic development. TGF beta 2/TGFB2 Protein, Mouse/Rat (HEK293) is produced in HEK293 cells, and consists of 112 amino acids (A303-S414).
  • HY-P74403
    B2M/Beta-2 microglobulin Protein, Mouse (HEK293, His)

    Beta-2-microglobulin; B2M

    		 Mouse HEK293
    Beta-2 microglobulin (B2M) is vital in presenting antigens to the immune system through MHC class I molecules. It forms a heterodimer with an alpha chain to create MHC class I molecules. B2M also forms a heterotrimer with MR1 and a metabolite antigen, enhancing antigen presentation and immune recognition. B2M's molecular interactions facilitate immune system functioning and foreign substance recognition. B2M/Beta-2 microglobulin Protein, Mouse (HEK293, His) is the recombinant mouse-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Mouse (HEK293, His) is 99 a.a., with molecular weight of ~14.5 kDa.
  • HY-P74404
    B2M/Beta-2 microglobulin Protein, Human (HEK293, His, solution)

    Beta-2-microglobulin; B2M

    		 Human HEK293
    B2M is a component of MHC class I complexes that present peptide antigens to the immune system. B2M/Beta-2 microglobulin Protein, Human (HEK293, His, solution) is the recombinant human-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Human (HEK293, His, solution) is 99 a.a., with molecular weight of ~13.5 kDa.
  • HY-P7625
    B2M/Beta-2-microglobulin Protein, Human (His)

    rHuBeta-2-microglobulin, His; Beta-2-Microglobulin; B2M

    		 Human E. coli
    B2M/Beta-2-microglobulin Protein, Human (His), a recombinant human Beta-2-microglobulin produced in E. coli, has a His tag. Beta-2-microglobulin acts as a modulator of lymphocyte surface and as a potential regulator of the immune system.
  • HY-P74402
    B2M/Beta-2 microglobulin Protein, Rat (119a.a, HEK293, His)

    Beta-2-microglobulin; B2M

    		 Rat HEK293
    Beta-2 microglobulin protein (B2M) is crucial in presenting antigens, aiding immune surveillance. B2M forms a complex with an alpha chain, creating MHC class I molecules for antigen recognition. It also participates in a heterotrimer with MR1, expanding its role in antigen presentation and immune signaling pathways. B2M's intricate interactions underscore its significance in orchestrating immune responses. B2M/Beta-2 microglobulin Protein, Rat (119a.a, HEK293, His) is the recombinant rat-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Rat (119a.a, HEK293, His) is 119 a.a., with molecular weight of ~15 kDa.
  • HY-P75592
    B2M/Beta-2 microglobulin Protein, Cynomolgus (119a.a, HEK293, His)

    Beta-2-microglobulin; B2M

    		 Cynomolgus HEK293
    B2M protein is essential for MHC class I complex, presenting antigens and enabling immune recognition. B2M forms heterodimers with alpha chains, constituting MHC class I molecules. Its participation ensures immune system function and foreign substance recognition. B2M/Beta-2 microglobulin Protein, Cynomolgus (119a.a, HEK293, His) is the recombinant cynomolgus-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Cynomolgus (119a.a, HEK293, His) is 119 a.a., with molecular weight of ~13 kDa.
  • HY-P78625
    B2M/Beta-2 microglobulin Protein, Rat (99a.a, HEK293, His)

    Beta-2-microglobulin; B2M

    		 Rat HEK293
    B2M or Beta-2 microglobulin binds to MHC class II protein complexes and forms homodimers. It responds to cadmium ions and exogenous stimuli and is present in the extracellular space. B2M/Beta-2 microglobulin Protein, Rat (99a.a, HEK293, His) is the recombinant rat-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Rat (99a.a, HEK293, His) is 99 a.a., with molecular weight of approximately 13 kDa.
  • HY-P700758
    Integrin alpha L beta 2 Protein, Mouse (HEK293, His)

    αLβ2; ITGAL&ITGB2; ITGAL; ITGB2

    		 Mouse HEK293
    Integrin alpha L beta 2 Protein, a receptor for ICAM1, ICAM2, ICAM3, ICAM4, and F11R, participates in immune phenomena, including leukocyte-endothelial cell interaction, cytotoxic T-cell killing, and antibody-dependent killing. It contributes to natural killer cell cytotoxicity and leukocyte adhesion and transmigration. Essential for common lymphoid progenitor cell generation, indicating a role in lymphopoiesis. In association with ICAM3, it contributes to apoptotic neutrophil phagocytosis by macrophages. Interacts with THBD. Integrin alpha L beta 2 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha L beta 2 protein, expressed by HEK293, with C-His labeled tag. Integrin alpha L beta 2 Protein, Mouse (HEK293, His), has molecular weight of 160-180 kDa (ITGAL) & 90-105 kDa (ITGB2), respectively.
  • HY-P73744
    NRG1-beta 2 Protein, Human (HEK293, His)

    Pro-NRG1; Neuregulin-1; ARIA; HRG; NRG1

    		 Human HEK293
    NRG1-alpha protein acts as a direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concurrently recruiting ERBB1 and ERBB2 coreceptors, thereby inducing ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The diverse functions of its multiple isoforms encompass the induction of growth and differentiation in various cell types, including epithelial, glial, neuronal, and skeletal muscle cells. NRG1-alpha is also involved in the expression of acetylcholine receptors during neuromuscular junction formation, the stimulation of lobuloalveolar budding and milk production in the mammary gland, and the induction of differentiation in mammary tumor cells. Furthermore, it stimulates Schwann cell proliferation and plays a role in myocardial development, specifically contributing to the trabeculation of the developing heart. Isoform 10 is implicated in motor and sensory neuron development. NRG1-alpha binds to ERBB4 and ERBB3, acting as a ligand for integrins and forming a ternary complex with integrins and ERBB3, a crucial step in NRG1-ERBB signaling. It induces the phosphorylation and activation of MAPK3/ERK1, MAPK1/ERK2, and AKT1. Additionally, NRG1-alpha participates in ligand-dependent ERBB4 endocytosis, essential for the activation of these kinases in neurons, and interacts with the LIM domain region of LIMK1. It also forms a ternary complex with ERBB3 and integrins ITGAV:ITGB3 or ITGA6:ITGB4 and interacts with NRDC and BACE1. NRG1-beta 2 Protein, Human (HEK293, His) is the recombinant human-derived NRG1-beta 2 protein, expressed by HEK293 , with C-His labeled tag. The total length of NRG1-beta 2 Protein, Human (HEK293, His) is 219 a.a., with molecular weight of ~25.3 kDa.
  • HY-P73745
    NRG1-beta 2 Protein, Human (HEK293, Fc)

    Pro-NRG1; Neuregulin-1; ARIA; HRG; NRG1

    		 Human HEK293
    NRG1-beta 2 is an important membrane glycoprotein that mediates intercellular signaling and affects the growth and development of organ systems. This gene produces multiple isoforms (types I-VI) with tissue-specific expression. NRG1-beta 2 Protein, Human (HEK293, Fc) is the recombinant human-derived NRG1-beta 2 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of NRG1-beta 2 Protein, Human (HEK293, Fc) is 61 a.a., with molecular weight of ~35.5 kDa.
  • HY-P74402A
    B2M/Beta-2 microglobulin Protein, Rat (119a.a, HEK293, C-His)

    Beta-2-microglobulin; B2M

    		 Rat HEK293
    Beta-2 microglobulin protein (B2M) is crucial in presenting antigens, aiding immune surveillance. B2M forms a complex with an alpha chain, creating MHC class I molecules for antigen recognition. It also participates in a heterotrimer with MR1, expanding its role in antigen presentation and immune signaling pathways. B2M's intricate interactions underscore its significance in orchestrating immune responses. B2M/Beta-2 microglobulin Protein, Rat (119a.a, HEK293, C-His) is the recombinant rat-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-6*His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Rat (119a.a, HEK293, C-His) is 119 a.a., with molecular weight of ~15 kDa.
  • HY-P71131
    Tryptase beta-2 Protein, Mouse (HEK293, His)
    1 Publications Verification

    Tryptase beta-2; Tryptase-2; Mast cell protease 6; mMCP-6

    		 Mouse HEK293
    Tryptase beta-2, a neutral protease abundant in mast cells, plays a key role in innate immunity. As the primary proteolytic enzyme released during mast cell activation, Tryptase beta-2 contributes significantly to immune functions. Its involvement underscores its importance in mediating cellular responses linked to innate immunity, highlighting its role in the intricate defense mechanisms of the immune system. Tryptase beta-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Tryptase beta-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Tryptase beta-2 Protein, Mouse (HEK293, His) is 255 a.a., with molecular weight of 32-38 kDa.
  • HY-P70046
    B2M/Beta-2-microglobulin Protein, Human (99a.a, HEK293, His)

    rHuBeta-2-microglobulin/B2M, His; Beta-2-Microglobulin; B2M

    		 Human HEK293
    B2M is a component of MHC class I complexes that present peptide antigens to the immune system. B2M/Beta-2-microglobulin Protein, Human (99a.a, HEK293, His) is the recombinant human-derived B2M/Beta-2-microglobulin protein, expressed by HEK293 , with C-6*His labeled tag. The total length of B2M/Beta-2-microglobulin Protein, Human (99a.a, HEK293, His) is 99 a.a., with molecular weight of ~14.0 kDa.
  • HY-P70086
    B2M/Beta-2 microglobulin Protein, Cynomolgus (99a.a, HEK293, His)

    rCynBeta-2-microglobulin/B2M, His; Beta-2-Microglobulin; B2M

    		 Cynomolgus HEK293
    B2M, also known as Beta-2 microglobulin, is a key component of the class I major histocompatibility complex (MHC) and plays a crucial role in presenting peptide antigens to the immune system (by similarity) . The protein forms a heterodimer with the α chain and specifically constitutes (by similarity) the β chain of major histocompatibility complex class I molecules. B2M/Beta-2 microglobulin Protein, Cynomolgus (99a.a, HEK293, His) is the recombinant cynomolgus-derived B2M/Beta-2 microglobulin protein, expressed by HEK293 , with C-6*His labeled tag. The total length of B2M/Beta-2 microglobulin Protein, Cynomolgus (99a.a, HEK293, His) is 99 a.a., with molecular weight of ~14.0 kDa.
  • HY-P71447
    GABRB2 Protein, Human (His)

    GABA(A) receptor subunit beta-2

    		 Human E. coli
    GABRB2 protein is an important component of heteropentameric GABA receptors that form ligand-gated chloride channels. It plays a crucial role in establishing functional inhibitory GABAergic synapses, contributing to synaptic depression. GABRB2 Protein, Human (His) is the recombinant human-derived GABRB2 protein, expressed by E. coli , with N-His labeled tag. The total length of GABRB2 Protein, Human (His) is 219 a.a., with molecular weight of ~29.3 kDa.
  • HY-P700749
    IL-6 Protein, Cynomolgus (HEK293, His)

    IFN-beta-2; IL6; IL-6; BSF-2; CDF; MGI-2A; Interleukin-6; HSF; IFNB2; HGF; IFN-β-2

    		 Cynomolgus HEK293
    IL-6 is a cytokine with multiple functions in immunity, tissue regeneration, and metabolism, coordinating complex signaling. Binding to IL6R initiates the IL6 signaling pathway through a complex with the signaling subunit IL6ST/gp130. IL-6 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-6 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-6 Protein, Cynomolgus (HEK293, His) is 185 a.a., with molecular weight of 25-30 kDa.
  • HY-P700660
    Apolipoprotein H/APOH Protein, Cynomolgus (HEK293, His)

    Apo-H; B2GP1; B2G1; APOH; B2GPI; beta(2)GPI; BG; β(2)GPI;

    		Cynomolgus HEK293
    Apolipoprotein H/APOH proteins have multiple functions and can bind to negatively charged substances such as heparin and phospholipids. Its diverse interactions highlight the adaptability that is critical for preventing activation of the intrinsic coagulation cascade by binding to phospholipids on the surface of damaged cells. Apolipoprotein H/APOH Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Apolipoprotein H/APOH protein, expressed by HEK293 , with C-His labeled tag. The total length of Apolipoprotein H/APOH Protein, Cynomolgus (HEK293, His) is 326 a.a., with molecular weight of 50-65 kDa.
  • HY-P7063
    IL-6 Protein, Mouse

    rMuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    		 Mouse E. coli
    IL-6 Protein, Mouse is a multifunctional cytokine that can regulate various immune and inflammatory responses.
  • HY-P7044
    IL-6 Protein, Human
    Maximum Cited Publications
    23 Publications Verification

    rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    		 Human E. coli
    IL-6 Protein, Human is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes.
  • HY-P7044G
    GMP IL-6 Protein, Human
    1 Publications Verification

    Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon Beta-2; IFN-Beta-2; IL6; IFNB2

    		 Human E. coli
    IL-6 protein is a multifunctional cytokine that plays multiple biological functions in immunity, tissue regeneration, and metabolism. After binding to IL6R, the resulting complex binds to the signaling subunit IL6ST/gp130, triggering the intracellular IL6 signaling pathway. GMP IL-6 Protein, Human is the recombinant human-derived IL-6 protein, expressed by E. coli , with tag free. GMP IL-6 Protein, Human, has molecular weight of ~20.0 kDa.
  • HY-P77488
    SIRP gamma Protein, Cynomolgus (HEK293, Fc)

    Signal-Regulatory Protein Gamma; CD172 Antigen-Like Family Member B; Signal-Fegulatory Protein Beta-2; SIRP-b2; SIRP-Beta-2; CD172g; SIRPG; SIRPB2

    		 Cynomolgus HEK293
    SIRP gamma Protein, a member of signal-regulatory protein (SIRP) family, is the only SIRP detected on T cells and activated NK cells. SIRP gamma can bind CD47, providing T cells and NK cells with a cell surface molecule capable of interacting with CD47. SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact, enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion. SIRP gamma Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived SIRP gamma protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SIRP gamma Protein, Cynomolgus (HEK293, Fc) is 360 a.a., with molecular weight of 69-79 kDa.
  • HY-P77489
    SIRP gamma Protein, Cynomolgus (HEK293, His)

    Signal-Regulatory Protein Gamma; CD172 Antigen-Like Family Member B; Signal-Fegulatory Protein Beta-2; SIRP-b2; SIRP-Beta-2; CD172g; SIRPG; SIRPB2

    		 Cynomolgus HEK293
    SIRP gamma Protein, a member of signal-regulatory protein (SIRP) family, is the only SIRP detected on T cells and activated NK cells. SIRP gamma can bind CD47, providing T cells and NK cells with a cell surface molecule capable of interacting with CD47. SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact, enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion. SIRP gamma Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived SIRP gamma protein, expressed by HEK293 , with C-His labeled tag. The total length of SIRP gamma Protein, Cynomolgus (HEK293, His) is 332 a.a., with molecular weight of ~45 kDa.
  • HY-P7044A
    IL-6 Protein, Human (CHO)
    1 Publications Verification

    rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    		 Human CHO
    IL-6 Protein, Human (CHO) is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes.
  • HY-P76051
    SCN2B Protein, Human (HEK293, Fc)

    Sodium channel subunit beta-2; SCN2B

    		 Human HEK293
    SCN2B protein is a key subunit of voltage-gated sodium channels and plays an important role in regulating channel function by interacting with the pore-forming α subunit. This interaction regulates the flux of sodium ions across the cell membrane, affecting neuronal excitability and action potential propagation. SCN2B Protein, Human (HEK293, Fc) is the recombinant human-derived SCN2B protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SCN2B Protein, Human (HEK293, Fc) is 159 a.a., with molecular weight of 53-57 kDa.
  • HY-P76052
    SCN2B Protein, Human (HEK293, His)

    Sodium channel subunit beta-2; SCN2B

    		 Human HEK293
    SCN2B protein is a key subunit of voltage-gated sodium channels and plays an important role in regulating channel function by interacting with the pore-forming α subunit. This interaction regulates the flux of sodium ions across the cell membrane, affecting neuronal excitability and action potential propagation. SCN2B Protein, Human (HEK293, His) is the recombinant human-derived SCN2B protein, expressed by HEK293 , with C-His labeled tag. The total length of SCN2B Protein, Human (HEK293, His) is 130 a.a., with molecular weight of 21-34 kDa.
  • HY-P700151AF
    Animal-Free TGF beta 2/TGFB2 Protein, Human (His)

    G-TSF; LDS4; TGFB2

    		 Human E. coli
    In the TGF-beta-2 pathway, TGF beta 2/TGFB2 protein acts as a precursor for Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2), regulating their formation. Crucially, TGF beta 2/TGFB2 maintains TGF-beta-2 in a latent state within the extracellular matrix, forming non-covalent associations with TGF-beta-2. Interactions with 'milieu molecules' like LTBP1 and LRRC32/GARP finely tune TGF-beta-2 activation, playing a pivotal role in controlling this critical signaling pathway. Animal-Free TGF beta 2/TGFB2 Protein, Human (His) is the recombinant human-derived animal-FreeTGF beta 2/TGFB2 protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free TGF beta 2/TGFB2 Protein, Human (His) is 112 a.a., with molecular weight of ~13.66 kDa.
  • HY-P7063A
    IL-6 Protein, Mouse (His)

    rMuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    		 Mouse E. coli
    IL-6 protein is involved in various functions such as immunity, tissue regeneration and metabolism. IL-6 Protein, Mouse (His) is the recombinant mouse-derived IL-6 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IL-6 Protein, Mouse (His) is 187 a.a., with molecular weight of ~24 kDa.
  • HY-P71316
    SIRP gamma Protein, Human (HEK293, Fc)

    Signal-Regulatory Protein Gamma; SIRP-Gamma; CD172 Antigen-Like Family Member B; Signal-Fegulatory Protein Beta-2; SIRP-b2; SIRP-Beta-2; CD172g; SIRPG; SIRPB2

    		 Human HEK293
    SIRP γ protein is a possible immunoglobulin-like cell surface receptor that mediates cell-cell adhesion by binding to CD47. This interaction enhances antigen-specific T cell proliferation and provides costimulatory signals for T cell activation, highlighting the role of SIRP gamma in regulating immune responses. SIRP gamma Protein, Human (HEK293, Fc) is the recombinant human-derived SIRP gamma protein, expressed by HEK293 , with C-hFc labeled tag. The total length of SIRP gamma Protein, Human (HEK293, Fc) is 332 a.a., with molecular weight of ~80.0 kDa.
  • HY-P7044AF
    Animal-Free IL-6 Protein, Human (His)

    Interleukin-6; IL-6; B-Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Hybridoma Growth Factor; Interferon Beta-2; IFN-Beta-2; IL6; IFNB2

    		 Human E. coli
    IL-6 protein is a multifunctional cytokine that plays multiple biological functions in immunity, tissue regeneration, and metabolism. After binding to IL6R, the resulting complex binds to the signaling subunit IL6ST/gp130, triggering the intracellular IL6 signaling pathway. Animal-Free IL-6 Protein, Human (His) is the recombinant human-derived animal-FreeIL-6 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-6 Protein, Human (His) is 184 a.a., with molecular weight of ~21.8 kDa.
  • HY-P7103A
    IL-6 Protein, Rat (HEK293)
    2 Publications Verification

    rRtIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    		 Rat HEK293
    IL-6 Protein, Rat (HEK293) is a HEK293 cell derived multifunctional cytokine that can regulate various immune and inflammatory responses.

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