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  4. Shishijimicin A

Shishijimicin A 

Cat. No.: HY-N10537
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Shishijimicin A is a novel antitumor agent found from the Ascidian Didemnum proliferum. Shishijimicin A shows anti-tumor activity with highly potent cytotoxicities.

For research use only. We do not sell to patients.

Shishijimicin A Chemical Structure

Shishijimicin A Chemical Structure

CAS No. : 503860-50-2

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Description

Shishijimicin A is a novel antitumor agent found from the Ascidian Didemnum proliferum. Shishijimicin A shows anti-tumor activity with highly potent cytotoxicities[1][2].

In Vitro

Shishijimicin A (compound 1) (0.47-2.0 pg/mL) shows high cytotoxicity for 3Y1, Hela and P388 cells[1].
Shishijimicin A (0.13-1000 nM) shows high cytotoxicity for MES SA, MES SA DX and HEK 293T cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: 3Y1, Hela and P388 cells
Concentration: 0.47-2.0 pg/mL
Incubation Time:
Result: Showed IC50 values of 2.0, 1.8, and 0.47 pg/mL for 3Y1, Hela and P388 cells, respectively.

Cell Cytotoxicity Assay[2]

Cell Line: MES SA, MES SA DX and HEK 293T cells
Concentration: 0.13-1000 nM
Incubation Time:
Result: Showed IC50 values of 0.13, >1000, and 0.016 nM for MES SA, MES SA DX and HEK 293T cells, respectively.
Molecular Weight

981.18

Formula

C46H52N4O12S4

CAS No.
SMILES

O=C(C1=C(NC2=CC=C3O)C(C2=C3)=CC=N1)[[email protected]@]([[email protected]@H]([[email protected]]4O[[email protected]](OC[[email protected]@H]5NC(C)C)C[[email protected]@H]5OC)O)([[email protected]](O[[email protected]]4O[[email protected]@H](C#C/C=C\C#C[[email protected]@]6(C7)O)C(/C6=C\CSSSC)=C(C7=O)NC(OC)=O)C)SC

Structure Classification
Source

Didemnum proliferum

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Shishijimicin A
Cat. No.:
HY-N10537
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