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  4. Shishijimicin B

Shishijimicin B 

Cat. No.: HY-N10538
Handling Instructions

Shishijimicin B is an active compound of the enediyne class. Shishijimicin B shows extremely potent cytotoxicity with IC50 values of 2.0-3.3 nM. Shishijimicin B has antitumor activity and can be used for the research of cancer.

For research use only. We do not sell to patients.

Shishijimicin B Chemical Structure

Shishijimicin B Chemical Structure

CAS No. : 503860-51-3

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Description

Shishijimicin B is an active compound of the enediyne class. Shishijimicin B shows extremely potent cytotoxicity with IC50 values of 2.0-3.3 nM. Shishijimicin B has antitumor activity and can be used for the research of cancer[1].

IC50 & Target

IC50: 3.1 nM (3Y1 cells); 3.3 nM (Hela cells); 2.0 nM (P388 cells)[1]

In Vitro

Shishijimicin B (compound 2) has high cytotoxicity for 3Y1, Hela and P388 cells with IC50 values of 3.1 nM, 3.3 nM and 2.0 nM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

935.09

Formula

C45H50N4O12S3

CAS No.
SMILES

CSSSC/C=C([[email protected]]1(C2)O)\C([[email protected]](C#C/C=C\C#C1)O[[email protected]](O[[email protected]@H]3C)[[email protected]@H]([[email protected]]([[email protected]@H]3C(C4=C(NC5=CC=C6O)C(C5=C6)=CC=N4)=O)O)O[[email protected]](OC[[email protected]@H]7NC(C)C)C[[email protected]@H]7OC)=C(C2=O)NC(OC)=O

Structure Classification
Source

Didemnum proliferum

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
Shishijimicin B
Cat. No.:
HY-N10538
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