1. Metabolic Enzyme/Protease
  2. Phosphatase
  3. SHP2-IN-6

SHP2-IN-6 

Cat. No.: HY-131132
Handling Instructions

SHP2-IN-6 is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM.

For research use only. We do not sell to patients.

SHP2-IN-6 Chemical Structure

SHP2-IN-6 Chemical Structure

CAS No. : 2169223-48-5

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Description

SHP2-IN-6 is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM[1].

In Vitro

SHP2-IN-6 inhibits the proliferation of KYSE-520 cells with an IC50 of 2.17 μM[1].

Molecular Weight

476.54

Formula

C₂₂H₂₆F₂N₆O₂S

CAS No.

2169223-48-5

SMILES

CC(N1CC(F)(F)C2=C1C=CC=C2SC3=NC=C(N(CC4)CCC54[[email protected]](N)COC5)N=C3N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

SHP2-IN-6Phosphatasenon-receptorproteintyrosinephosphatasePTPN11cancerInhibitorinhibitorinhibit

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SHP2-IN-6
Cat. No.:
HY-131132
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