1. Apoptosis
    Cell Cycle/DNA Damage
  2. Apoptosis
    DNA/RNA Synthesis
  3. T-​2 Toxin

T-​2 Toxin (Synonyms: T-2 Mycotoxin)

Cat. No.: HY-N6792
Handling Instructions

T-2 Toxin (T-2 Mycotoxin) is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains, LD50 values of T-2 Toxin in mice and rats are 5.2 and 1.5 mg/kg BWa,respectively . T-2 Toxin (T-2 Mycotoxin) can be transformed into a variety of metabolite, the typical metabolites of T-2 toxin in animals are HT-2 toxin and T-2-triol, which are hydrolysates. T-2 Toxin (T-2 Mycotoxin) is an inhibitor of protein synthesis resulting from binding peptidyltransferase, which is an integral part of the 60s ribosomal subunit. T-2 Toxin (T-2 Mycotoxin) inhibits the synthesis of DNA and RNA, interferes with the metabolism of membrane phospholipids, and increases the level of liver lipid peroxides. T-2 Toxin (T-2 Mycotoxin) induces apoptosis in the immune system, gastrointestinal tissues, and fetal tissues.

For research use only. We do not sell to patients.

T-​2 Toxin Chemical Structure

T-​2 Toxin Chemical Structure

CAS No. : 21259-20-1

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Description

T-2 Toxin (T-2 Mycotoxin) is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains, LD50 values of T-2 Toxin in mice and rats are 5.2 and 1.5 mg/kg BWa,respectively [1]. T-2 Toxin (T-2 Mycotoxin) can be transformed into a variety of metabolite, the typical metabolites of T-2 toxin in animals are HT-2 toxin and T-2-triol, which are hydrolysates[1]. T-2 Toxin (T-2 Mycotoxin) is an inhibitor of protein synthesis resulting from binding peptidyltransferase, which is an integral part of the 60s ribosomal subunit. T-2 Toxin (T-2 Mycotoxin) inhibits the synthesis of DNA and RNA, interferes with the metabolism of membrane phospholipids, and increases the level of liver lipid peroxides[1]. T-2 Toxin (T-2 Mycotoxin) induces apoptosis in the immune system, gastrointestinal tissues, and fetal tissues[2].

Molecular Weight

468.54

Formula

C₂₄H₃₆O₉

CAS No.

21259-20-1

SMILES

CC12C3(CO3)[[email protected]@](O[[email protected]@](/C=C(C)\[[email protected]@H](OC(CC(C)C)=O)C)([H])[[email protected]]2COC(C)=O)([H])[[email protected]](O)[[email protected]]1OC(C)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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T-​2 Toxin
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