1. Anti-infection
    Metabolic Enzyme/Protease
  2. Parasite
    Drug Metabolite
  3. Thalifendine chloride

Thalifendine chloride 

Cat. No.: HY-N2023A
Handling Instructions

Thalifendine chloride is a metabolite of Berberine (HY-N0716), with antiplasmodial and antiamoebic activities. Thalifendine chloride shows activity against P. falciparum and E. histolytica with IC50s of 7.91 μM and 116 μM, respectively.

For research use only. We do not sell to patients.

Thalifendine chloride Chemical Structure

Thalifendine chloride Chemical Structure

CAS No. : 4668-19-3

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Description

Thalifendine chloride is a metabolite of Berberine (HY-N0716), with antiplasmodial and antiamoebic activities. Thalifendine chloride shows activity against P. falciparum and E. histolytica with IC50s of 7.91 μM and 116 μM, respectively[1][2].

IC50 & Target

IC50: 7.91μM (P. falciparum), 116 μM (E. histolytica)[2]

Molecular Weight

357.79

Formula

C₁₉H₁₆ClNO₄

CAS No.

4668-19-3

SMILES

COC1=C(O)C=CC2=CC3=[N+](C=C21)CCC(C3=C4)=CC5=C4OCO5.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

ThalifendineParasiteDrug MetaboliteCYP450BerberinemetaboliteantiplasmodialP. falciparum,antiamoebicE. histolyticaThalictrumfoliolosumInhibitorinhibitorinhibit

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Thalifendine chloride
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