1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. Tipiracil hydrochloride

Tipiracil hydrochloride 

Cat. No.: HY-A0063 Purity: 99.94%
Handling Instructions

Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.

For research use only. We do not sell to patients.

Tipiracil hydrochloride Chemical Structure

Tipiracil hydrochloride Chemical Structure

CAS No. : 183204-72-0

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in Water USD 66 In-stock
Estimated Time of Arrival: December 31
5 mg USD 60 In-stock
Estimated Time of Arrival: December 31
10 mg USD 90 In-stock
Estimated Time of Arrival: December 31
50 mg USD 180 In-stock
Estimated Time of Arrival: December 31
100 mg USD 240 In-stock
Estimated Time of Arrival: December 31
200 mg USD 312 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Tipiracil hydrochloride:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.

In Vitro

Tipiracil has antiangiogenic effect, and inhibits proliferation of endothelial cells[1]. Tipiracil is a potent inhibitor of thymidine phosphorylase, which is the enzyme that degrades FTD[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

279.12

Formula

C₉H₁₂Cl₂N₄O₂

CAS No.

183204-72-0

SMILES

[H]Cl.O=C1C(Cl)=C(CN2C(CCC2)=N)NC(N1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (179.13 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

DMF : < 1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5827 mL 17.9134 mL 35.8269 mL
5 mM 0.7165 mL 3.5827 mL 7.1654 mL
10 mM 0.3583 mL 1.7913 mL 3.5827 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.94%

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Keywords:

TipiracilNucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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Product Name:
Tipiracil hydrochloride
Cat. No.:
HY-A0063
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