1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. Tipiracil hydrochloride

Tipiracil hydrochloride 

Cat. No.: HY-A0063 Purity: 98.77%
COA Handling Instructions

Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.

For research use only. We do not sell to patients.

Tipiracil hydrochloride Chemical Structure

Tipiracil hydrochloride Chemical Structure

CAS No. : 183204-72-0

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 73 In-stock
Solution
10 mM * 1 mL in Water USD 73 In-stock
Solid
5 mg USD 66 In-stock
10 mg USD 99 In-stock
50 mg USD 198 In-stock
100 mg USD 264 In-stock
200 mg USD 343 In-stock
500 mg   Get quote  
1 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 5 publication(s) in Google Scholar

Other Forms of Tipiracil hydrochloride:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.

In Vitro

Tipiracil has antiangiogenic effect, and inhibits proliferation of endothelial cells[1].
Tipiracil is a potent inhibitor of thymidine phosphorylase, which is the enzyme that degrades FTD[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

279.12

Formula

C9H12Cl2N4O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[H]Cl.O=C1C(Cl)=C(CN2C(CCC2)=N)NC(N1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (179.13 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

DMF : < 1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5827 mL 17.9134 mL 35.8269 mL
5 mM 0.7165 mL 3.5827 mL 7.1654 mL
10 mM 0.3583 mL 1.7913 mL 3.5827 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (89.57 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: 98.86%

References
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Tipiracil hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Tipiracil hydrochloride
Cat. No.:
HY-A0063
Quantity:
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