1. Anti-infection
    Antibody-drug Conjugate/ADC Related
  2. Fungal
    Antibiotic
    ADC Cytotoxin
  3. Tolytoxin

Tolytoxin 

Cat. No.: HY-130998
Handling Instructions

Tolytoxin, a bioactive metabolite from cyanobacteria, is a potent antifungal antibiotic, exhibiting MICs of 0.25-8 nmol. Tolytoxin is a cyanobacterial macrolide that targets actin by inhibition of its polymerization. Tolytoxin has cytotoxic effects in cancer cells.

For research use only. We do not sell to patients.

Tolytoxin Chemical Structure

Tolytoxin Chemical Structure

CAS No. : 127999-44-4

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Description

Tolytoxin, a bioactive metabolite from cyanobacteria, is a potent antifungal antibiotic, exhibiting MICs of 0.25-8 nmol. Tolytoxin is a cyanobacterial macrolide that targets actin by inhibition of its polymerization. Tolytoxin has cytotoxic effects in cancer cells[1].

In Vivo

Tolytoxin is highly toxic to mice, exhibiting an LD50 (ip) of 1.5 mg/kg.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

850.09

Formula

C₄₆H₇₅NO₁₃

CAS No.

127999-44-4

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

TolytoxinFungalAntibioticADC CytotoxinInhibitorinhibitorinhibit

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Product Name:
Tolytoxin
Cat. No.:
HY-130998
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