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TREM2 agonist-1 

Cat. No.: HY-148094
Handling Instructions

TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells 2 (TREM2) agonist (EC50 between 3.0 μM and 100 μM).

For research use only. We do not sell to patients.

TREM2 agonist-1 Chemical Structure

TREM2 agonist-1 Chemical Structure

CAS No. : 2738486-70-7

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TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells 2 (TREM2) agonist (EC50 between 3.0 μM and 100 μM)[1].

In Vitro

TREM2 agonist-1 (0-100 μM; 16 h) treatment activates hTREM2 in HEK293 cell[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: HEK293 cells
Concentration: 0-100 μM
Incubation Time: 16 hours
Result: Showed an EC50 value between 3.0 μM and 100 μM.
Molecular Weight





FC1=C(C=CC(Cl)=C1)C2=NC([[email protected]@H]3C[[email protected]@H](C4=CN(N=C4)C)OCC3)=CC5=C2N=CC(C)=N5


Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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