1. THAM acetate

THAM acetate  (Synonyms: Tris acetate; Tris(hydroxymethyl)aminomethane acetate)

Cat. No.: HY-D0227B Purity: ≥99.0%
COA Handling Instructions

Trometamol acetate (Tromethamine acetate) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol acetate is an effective amine compound for pH control in the physiological range.

For research use only. We do not sell to patients.

THAM acetate Chemical Structure

THAM acetate Chemical Structure

CAS No. : 6850-28-8

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Other Forms of THAM acetate:

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Description

Trometamol acetate (Tromethamine acetate) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol acetate is an effective amine compound for pH control in the physiological range[1].

Clinical Trial
Molecular Weight

181.19

Formula

C6H15NO5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCC(CO)(N)CO.OC(C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (551.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.5191 mL 27.5953 mL 55.1907 mL
5 mM 1.1038 mL 5.5191 mL 11.0381 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.5191 mL 27.5953 mL 55.1907 mL 137.9767 mL
5 mM 1.1038 mL 5.5191 mL 11.0381 mL 27.5953 mL
10 mM 0.5519 mL 2.7595 mL 5.5191 mL 13.7977 mL
15 mM 0.3679 mL 1.8397 mL 3.6794 mL 9.1984 mL
20 mM 0.2760 mL 1.3798 mL 2.7595 mL 6.8988 mL
25 mM 0.2208 mL 1.1038 mL 2.2076 mL 5.5191 mL
30 mM 0.1840 mL 0.9198 mL 1.8397 mL 4.5992 mL
40 mM 0.1380 mL 0.6899 mL 1.3798 mL 3.4494 mL
50 mM 0.1104 mL 0.5519 mL 1.1038 mL 2.7595 mL
60 mM 0.0920 mL 0.4599 mL 0.9198 mL 2.2996 mL
80 mM 0.0690 mL 0.3449 mL 0.6899 mL 1.7247 mL
100 mM 0.0552 mL 0.2760 mL 0.5519 mL 1.3798 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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THAM acetate
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HY-D0227B
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