1. Cell Cycle/DNA Damage
  2. Deubiquitinase
  3. USP7-IN-5

USP7-IN-5 

Cat. No.: HY-129168
Handling Instructions

USP7-IN-5 is a potent ubiquitin specific protease 7 (USP7) inhibitor extracted from patent WO2017212012A1, example 40, has an IC50 of 49.9 nM.

For research use only. We do not sell to patients.

USP7-IN-5 Chemical Structure

USP7-IN-5 Chemical Structure

CAS No. : 2166599-74-0

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Description

USP7-IN-5 is a potent ubiquitin specific protease 7 (USP7) inhibitor extracted from patent WO2017212012A1, example 40, has an IC50 of 49.9 nM[1].

IC50 & Target

IC50: 49.9 nM (USP7)[1]

In Vitro

USP7-IN-5 (example 40) shows cytotoxicity to MM1S cells, with an IC50 31.5 nM[1].

Molecular Weight

641.76

Formula

C₃₆H₄₃N₅O₆

CAS No.

2166599-74-0

SMILES

O=C(N1C[[email protected]@H](C2=CC=CC=C2)[[email protected]](C(N3CCC(O)(CN(C=NC4=C5C=CN4C6=CC=C(OC)C=C6)C5=O)CC3)=O)CC1)OC(C)(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

USP7-IN-5DeubiquitinaseDUBsMM1ScytotoxicitycellstumorInhibitorinhibitorinhibit

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USP7-IN-5
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