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Vasomera is a stable long-acting vasoactive intestinal peptide (VIP) agonist. Vasomera acts on the G-protein-coupled VPAC2-receptors. Vasomera can be used for the research of cardiomyopathy associated with dystrophinopathies.

For research use only. We do not sell to patients.

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Vasomera Chemical Structure

Vasomera Chemical Structure

CAS No. : 1416067-68-9

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Description

Vasomera is a stable long-acting vasoactive intestinal peptide (VIP) agonist. Vasomera acts on the G-protein-coupled VPAC2-receptors. Vasomera can be used for the research of cardiomyopathy associated with dystrophinopathies[1].

In Vivo

Vasomera (i.v.; 7.5 μg/kg/min; single) improves arterial elastance and ventriculo-arterial coupling and improves indices of diastolic function (i.e., lusitropy) in animals with chronic renoprival hypertension mimicking heart failure with preserved ejection fraction (HFpEF)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rats[1]
Dosage: 7.5 μg/kg
Administration: IV, 7.5 μg/kg/min, single
Result: Decreased the estimated arterial elastance, improved ventriculo-arterial coupling, reduced filling pressures, accelerated the time-constant of relaxation and improved compliance.
Clinical Trial
CAS No.
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Keywords:

Vasomera1416067-68-9Otherslong-actingvasoactive intestinal peptide (VIP)G-proteindystrophinopathiesInhibitorinhibitorinhibit

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