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  2. Virtual Screening
  3. Serine Hydrolase Library

Serine Hydrolase Library

Cat. No.: HY-L0069V

Serine hydrolase library is a library of 12,040 precisely selected compounds able to form covalent bonds with catalytic Serine residue.

Serine Hydrolase Library
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100 μL/well (10 mM solution) Get quote In-stock

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Description
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Advantages

•   A unique library of 12,040 diverse compounds able to form covalent bonds with catalytic serine residue.

•   Serine hydrolases are one of the largest known enzyme classes comprising approximately ~200 enzymes or 1% of the genes in the human proteome.

•   The main criteria of the selection was presence of the electrophilic group (eg. CN, epoxide, carbonyl etc.) which can provide the key interaction with serine in the active site.

•   No PAINS (Pan Assay Interference Compounds), only medchem friendly compounds.

•   Structurally diverse.

•   Molecular properties: 100% Ro5 compliant, and 99.5 % lead-like.

•   NMR and HPLC validated to ensure high purity and quality.

•   All compounds can be readily followed with analogues either from stock or from new syntheses.

•   Databases and compounds are provided by Enamine.

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Serine Hydrolase Library
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